BR9611897A - Benzofurano carboxamidas e sulfonamidas - Google Patents

Benzofurano carboxamidas e sulfonamidas

Info

Publication number
BR9611897A
BR9611897A BR9611897-0A BR9611897A BR9611897A BR 9611897 A BR9611897 A BR 9611897A BR 9611897 A BR9611897 A BR 9611897A BR 9611897 A BR9611897 A BR 9611897A
Authority
BR
Brazil
Prior art keywords
sulfonamides
carboxamides
benzofuran carboxamides
benzofuran
benzofurano
Prior art date
Application number
BR9611897-0A
Other languages
English (en)
Inventor
Hazel Joan Dyke
Hannah Jayne Kendall
Christopher Lowe
John Gary Montana
Original Assignee
Darwin Discovery Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9524832.4A external-priority patent/GB9524832D0/en
Priority claimed from GBGB9610515.0A external-priority patent/GB9610515D0/en
Priority claimed from GBGB9610712.3A external-priority patent/GB9610712D0/en
Application filed by Darwin Discovery Ltd filed Critical Darwin Discovery Ltd
Publication of BR9611897A publication Critical patent/BR9611897A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/80—Radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/86—Benzo [b] furans; Hydrogenated benzo [b] furans with an oxygen atom directly attached in position 7
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Patente de Invenção: <B>"BENZOFURANO CARBOXAMIDAS E SULFONAMIDAS"<D>. As benzofurano carboxamidas e sulfonamidas possuem utilidade terapêuticas, por exemplo, no tratamento de inflamações e asma, em virtude de sua capacidade de inibir as fosfodiesterases e o fator de necrose de tumores.
BR9611897-0A 1995-12-05 1996-12-05 Benzofurano carboxamidas e sulfonamidas BR9611897A (pt)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GBGB9524832.4A GB9524832D0 (en) 1995-12-05 1995-12-05 Novel compounds
GBGB9610515.0A GB9610515D0 (en) 1996-05-20 1996-05-20 Novel compounds
GBGB9610712.3A GB9610712D0 (en) 1995-12-05 1996-05-22 Novel compounds
PCT/GB1996/003012 WO1997020833A1 (en) 1995-12-05 1996-12-05 Benzofuran carboxamides and sulphonamides

Publications (1)

Publication Number Publication Date
BR9611897A true BR9611897A (pt) 1999-12-28

Family

ID=27268015

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9611897-0A BR9611897A (pt) 1995-12-05 1996-12-05 Benzofurano carboxamidas e sulfonamidas

Country Status (16)

Country Link
US (1) US5773467A (pt)
EP (1) EP0873331B1 (pt)
JP (1) JP2000501411A (pt)
KR (1) KR19990071894A (pt)
CN (1) CN1100773C (pt)
AT (1) ATE215540T1 (pt)
AU (1) AU697976B2 (pt)
BR (1) BR9611897A (pt)
CA (1) CA2238376C (pt)
CZ (1) CZ292443B6 (pt)
DE (1) DE69620458T2 (pt)
ES (1) ES2172695T3 (pt)
HU (1) HUP9903797A3 (pt)
NO (1) NO982570L (pt)
PL (1) PL327181A1 (pt)
WO (1) WO1997020833A1 (pt)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2162467C2 (ru) * 1996-05-20 2001-01-27 Дарвин Дискавери Лимитед Карбоксамиды бензофурана и их фармацевтическая композиция
DE69717827T2 (de) * 1996-08-19 2003-09-04 Altana Pharma Ag Benzofuran-4-carboxamide
ATE237612T1 (de) * 1997-10-01 2003-05-15 Kyowa Hakko Kogyo Kk Benzofuranderivate
WO1999037640A1 (fr) * 1998-01-26 1999-07-29 Kyowa Hakko Kogyo Co., Ltd. Composes heterocycliques oxygenes
WO1999040085A1 (en) * 1998-02-09 1999-08-12 Darwin Discovery Limited Benzofuran-4-carboxamides and their therapeutic use
FR2778662B1 (fr) * 1998-05-12 2000-06-16 Adir Nouveaux composes cycliques substitues, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
TW555759B (en) * 1998-06-08 2003-10-01 Darwin Discovery Ltd Heterocyclic compounds and their therapeutic use
JP2002517495A (ja) * 1998-06-10 2002-06-18 ビイク グルデン ロンベルク ヒエーミツシエ フアブリーク ゲゼルシヤフト ミツト ベシユレンクテル ハフツング ホスホジエステラーゼ４の阻害剤としてのテトラヒドロフラニルオキシ置換基を有するベンズアミド
DE60043318D1 (de) 1999-08-21 2010-01-14 Nycomed Gmbh Synergistische kombination von pumafentrine und salmeterol
US7217722B2 (en) 2000-02-01 2007-05-15 Kirin Beer Kabushiki Kaisha Nitrogen-containing compounds having kinase inhibitory activity and drugs containing the same
GB0011802D0 (en) * 2000-05-16 2000-07-05 Smithkline Beecham Method for enhancing cognitive function
FR2903106B1 (fr) * 2006-07-03 2010-07-30 Sanofi Aventis Utilisations de 2-benzoyl-imidazopyridines en therapeutique
EP2196465A1 (en) 2008-12-15 2010-06-16 Almirall, S.A. (3-oxo)pyridazin-4-ylurea derivatives as PDE4 inhibitors
AR074760A1 (es) * 2008-12-18 2011-02-09 Metabolex Inc Agonistas del receptor gpr120 y usos de los mismos en medicamentos para el tratamiento de diabetes y el sindrome metabolico.
EP2226323A1 (en) 2009-02-27 2010-09-08 Almirall, S.A. New tetrahydropyrazolo[3,4-c]isoquinolin-5-amine derivatives
EP2380890A1 (en) 2010-04-23 2011-10-26 Almirall, S.A. New 7,8-dihydro-1,6-naphthyridin-5(6h)-one-derivatives as PDE4 inhibitors
EP2394998A1 (en) 2010-05-31 2011-12-14 Almirall, S.A. 3-(5-Amino-6-oxo-1,6-dihydropyridazin-3-yl)-biphenyl derivatives as PDE4 inhibitors
CN103003270B (zh) 2010-07-22 2014-11-12 扶桑药品工业株式会社 苯并呋喃酮化合物以及含有该化合物的药物组合物
EP3242661B1 (en) 2015-01-05 2019-08-21 The U.S.A. as represented by the Secretary, Department of Health and Human Services Myc g-quadruplex stabilizing small molecules and their use
CN114149457B (zh) * 2021-11-03 2024-04-12 湖北民族大学 一种苯并[c][1,2]氧杂硼戊环-1(3H)-醇类合物及其用途

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES8705871A1 (es) * 1984-12-29 1987-05-16 Kaken Pharma Co Ltd Un procedimiento para preparar un derivado de benzofurano
DE69507197T2 (de) * 1994-05-31 1999-05-27 Bayer Ag, 51373 Leverkusen Aminobenzofuryl- und -thienylderivate
ATE196765T1 (de) * 1994-07-22 2000-10-15 Byk Gulden Lomberg Chem Fab Dihydrobenzofurane
AU705690B2 (en) * 1995-05-19 1999-05-27 Kyowa Hakko Kogyo Co. Ltd. Oxygen-containing heterocyclic compounds
RU2162467C2 (ru) * 1996-05-20 2001-01-27 Дарвин Дискавери Лимитед Карбоксамиды бензофурана и их фармацевтическая композиция

Also Published As

Publication number Publication date
HUP9903797A2 (hu) 2001-04-28
CN1208411A (zh) 1999-02-17
HUP9903797A3 (en) 2001-08-28
ES2172695T3 (es) 2002-10-01
CZ292443B6 (cs) 2003-09-17
NO982570D0 (no) 1998-06-04
DE69620458D1 (de) 2002-05-08
CA2238376C (en) 2006-08-15
WO1997020833A1 (en) 1997-06-12
US5773467A (en) 1998-06-30
PL327181A1 (en) 1998-11-23
CN1100773C (zh) 2003-02-05
EP0873331A1 (en) 1998-10-28
KR19990071894A (ko) 1999-09-27
AU1038697A (en) 1997-06-27
AU697976B2 (en) 1998-10-22
CZ171498A3 (cs) 1998-10-14
MX9804466A (es) 1998-12-31
JP2000501411A (ja) 2000-02-08
EP0873331B1 (en) 2002-04-03
DE69620458T2 (de) 2002-10-02
CA2238376A1 (en) 1997-06-12
ATE215540T1 (de) 2002-04-15
NO982570L (no) 1998-08-04

Similar Documents

Publication Publication Date Title
BR9611897A (pt) Benzofurano carboxamidas e sulfonamidas
EA200100524A1 (ru) Амиды антраниловой кислоты и их применение в качестве лекарственных средств
BRPI0113286B8 (pt) pirazóis substituídos e composição farmacêutica compreendendo os mesmos.
MXPA04005376A (es) Composiciones farmaceuticas y sus usos.
EE03969B1 (et) (Metüülsulfonüül)fenüül-2-(5H)-furanoonid, nende kasutamine ja farmatseutilised kompositsioonid
CA2400217A1 (en) Pteridine compounds for the treatment of psoriasis
YU83502A (sh) Nova farmaceutska smeša
BR9917038A (pt) Composto, composição farmacêutica, método de modulação da atividade receptora de quimocinas, método de tratamento ou prevenção de doenças inflamatórias, método de tratamento ou prevenção de asma e método de tratamento ou prevenção de disfunções inflamatórias
BR0206985A (pt) Anticorpos modificados e métodos de uso
BR9813028A (pt) Agonistas de prostaglandina e seu uso para tratar distúrbios nos ossos
ZA98214B (en) Treatment of multiple sclerosis through ingestion or inhalation of copolymer-1.
BR0114344A (pt) Retinóides para o tratamento de enfisema
ATE438618T1 (de) Inhibitoren von humanem adam-10
CA2415354A1 (en) Phospholipid derivatives of valproic acid and mixtures thereof
BRPI0414215A (pt) tienopirazóis
PT832081E (pt) Compostos biciclicos aromaticos
CA2451519A1 (en) Tablet comprising cetirizine and pseudoephedrine
ES2088128T3 (es) Aminosulfonilureas inhibidoras de acat.
ID28365A (id) Turunan produk alami yang baru
BR0206819A (pt) Uso de inibidores de il-18 para o tratamento e/ou para a prevenção de doença cardìaca
BR9814945A (pt) Utilização de fanquinona para o tratamento de doença de alzheimer, composição farmacêutica e kit
TR200200278T2 (tr) Kalsilitik bileşimler
BR0010560A (pt) 3-piridil-4-arilpirrois substituìdos e métodos terapêuticos e profiláticos relacionados
AP9701142A0 (en) 4,4-(Disubstituted) cyclohexan-1-ols monomers and related compounds.
DE60003074D1 (de) Fusidinsäure-derivate

Legal Events

Date Code Title Description
FB36 Technical and formal requirements: requirement - article 36 of industrial property law
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 8A E 9A ANUIDADES.