ATE229516T1 - Benzofuran-4-carboxamide - Google Patents

Benzofuran-4-carboxamide

Info

Publication number
ATE229516T1
ATE229516T1 AT97942858T AT97942858T ATE229516T1 AT E229516 T1 ATE229516 T1 AT E229516T1 AT 97942858 T AT97942858 T AT 97942858T AT 97942858 T AT97942858 T AT 97942858T AT E229516 T1 ATE229516 T1 AT E229516T1
Authority
AT
Austria
Prior art keywords
benzofuran
carboxamide
substituted
optionally
flourine
Prior art date
Application number
AT97942858T
Other languages
English (en)
Inventor
Wolf-Ruediger Ulrich
Dieter Flockerzi
Beate Schmidt
Ulrich Thibaut
Armin Hatzelmann
Christian Schudt
Rolf Beume
Dietrich Haefner
Hans-Peter Kley
Hermann Amschler
Original Assignee
Altana Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Altana Pharma Ag filed Critical Altana Pharma Ag
Application granted granted Critical
Publication of ATE229516T1 publication Critical patent/ATE229516T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
AT97942858T 1996-08-19 1997-08-13 Benzofuran-4-carboxamide ATE229516T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19633052 1996-08-19
PCT/EP1997/004398 WO1998007715A1 (de) 1996-08-19 1997-08-13 Novel benzofuran-4-carboxamides

Publications (1)

Publication Number Publication Date
ATE229516T1 true ATE229516T1 (de) 2002-12-15

Family

ID=7802799

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97942858T ATE229516T1 (de) 1996-08-19 1997-08-13 Benzofuran-4-carboxamide

Country Status (11)

Country Link
US (1) US6211203B1 (de)
EP (1) EP0923568B9 (de)
JP (1) JP4309475B2 (de)
AT (1) ATE229516T1 (de)
AU (1) AU4454597A (de)
CY (1) CY2458B1 (de)
DE (1) DE69717827T2 (de)
DK (1) DK0923568T5 (de)
ES (1) ES2188983T4 (de)
PT (1) PT923568E (de)
WO (1) WO1998007715A1 (de)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ332340A (en) * 1996-05-20 2000-04-28 Darwin Discovery Ltd 4-(aryl or heteroaryl) substituted benzofurancarboxamide derivatives and medicaments
EP1054884A1 (de) * 1998-02-09 2000-11-29 Darwin Discovery Limited Benzofuran-4-carboxamide und ihre therapeutische anwendung
TW555759B (en) * 1998-06-08 2003-10-01 Darwin Discovery Ltd Heterocyclic compounds and their therapeutic use
PT1086096E (pt) 1998-06-10 2003-12-31 Altana Pharma Ag Benzamidas com substituintes etra-hidrofuraniloxi como inibidores da fosfodiesterase 4
EP1129068A1 (de) * 1998-11-12 2001-09-05 Ariad Pharmaceuticals, Inc. Bizyclische inhibitoren von signal-transduktion, sie enthaltende zusammensetzungen und ihre verwendungen
DE19924340A1 (de) 1999-05-27 2000-11-30 Basf Ag Verfahren zur selektiven Hydrierung von ethylenisch ungesättigten Doppelbindungen in Polymeren
JP5038568B2 (ja) 1999-08-21 2012-10-03 ニコメッド ゲゼルシャフト ミット ベシュレンクテル ハフツング 協力剤の組合せ物
GB0003257D0 (en) * 2000-02-11 2000-04-05 Darwin Discovery Ltd Heterocyclic compounds and their therapeutic use
EP2258359A3 (de) 2005-08-26 2011-04-06 Braincells, Inc. Neurogenese durch Modulation des Muscarinrezeptors mit Sabcomelin
JP2009506069A (ja) 2005-08-26 2009-02-12 ブレインセルス，インコーポレイティド ムスカリン性受容体調節による神経発生
AU2006304787A1 (en) 2005-10-21 2007-04-26 Braincells, Inc. Modulation of neurogenesis by PDE inhibition
CA2625210A1 (en) 2005-10-31 2007-05-10 Braincells, Inc. Gaba receptor mediated modulation of neurogenesis
US20100216734A1 (en) 2006-03-08 2010-08-26 Braincells, Inc. Modulation of neurogenesis by nootropic agents
US7842713B2 (en) * 2006-04-20 2010-11-30 Pfizer Inc Fused phenyl amido heterocyclic compounds
EP2026813A2 (de) 2006-05-09 2009-02-25 Braincells, Inc. 5-ht-rezeptor-vermittelte neurogenese
EP2377531A2 (de) 2006-05-09 2011-10-19 Braincells, Inc. Neurogenese mittels Angiotensin-Modulation
US7998971B2 (en) 2006-09-08 2011-08-16 Braincells Inc. Combinations containing a 4-acylaminopyridine derivative
US20100184806A1 (en) 2006-09-19 2010-07-22 Braincells, Inc. Modulation of neurogenesis by ppar agents
EP2344458A1 (de) 2008-09-11 2011-07-20 Pfizer Inc. Heteroarylamidderivate und ihre verwendung als glucokinase-aktivatoren
AR074760A1 (es) * 2008-12-18 2011-02-09 Metabolex Inc Agonistas del receptor gpr120 y usos de los mismos en medicamentos para el tratamiento de diabetes y el sindrome metabolico.
US20100216805A1 (en) 2009-02-25 2010-08-26 Braincells, Inc. Modulation of neurogenesis using d-cycloserine combinations
EA018894B1 (ru) * 2009-03-11 2013-11-29 Пфайзер Инк. N,n-диметил-5-(2-метил-6-((5-метилпиразин-2-ил)карбамоил)бензо-фуран-4-илокси)пиримидин-2-карбоксамид, используемый в качестве активатора глюкокиназы, и содержащая его фармацев-тическая композиция
RU2446143C2 (ru) * 2010-05-19 2012-03-27 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Ярославский государственный технический университет" (ЯГТУ) Способ получения эфиров замещенных 5,6-дицианобензофуран-2-карбоновых кислот
US8299117B2 (en) 2010-06-16 2012-10-30 Metabolex Inc. GPR120 receptor agonists and uses thereof
CA2801182A1 (en) * 2010-06-16 2011-12-22 Metabolex, Inc. Gpr120 receptor agonists and uses thereof
EP2804603A1 (de) 2012-01-10 2014-11-26 President and Fellows of Harvard College Betazellen-replikation für promoterverbindungen und verwendungsverfahren dafür
EP3708567A4 (de) * 2017-11-10 2021-07-07 Jiangsu Hengrui Medicine Co., Ltd. Verfahren zur herstellung eines benzofuranderivats

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ290266B6 (cs) * 1993-07-02 2002-06-12 Byk Gulden Lomberg Chemische Fabrik Gmbh Substituované benzamidy, způsob jejich výroby a farmaceutické prostředky s jejich obsahem
US6121274A (en) * 1994-07-22 2000-09-19 Byk Gulden Lomberg Chemische Fabrik Gmbh Dihydrobenzofurane
JP4172817B2 (ja) * 1995-05-19 2008-10-29 協和醗酵工業株式会社 含酸素複素環化合物
HUP9903797A3 (en) * 1995-12-05 2001-08-28 Darwin Discovery Ltd Milton Ro Benzofuran carboxamides and sulphonamides, their use for producing medicaments and such medicaments
NZ332340A (en) * 1996-05-20 2000-04-28 Darwin Discovery Ltd 4-(aryl or heteroaryl) substituted benzofurancarboxamide derivatives and medicaments

Also Published As

Publication number Publication date
JP4309475B2 (ja) 2009-08-05
WO1998007715A1 (de) 1998-02-26
WO1998007715A9 (de) 1999-04-29
CY2458B1 (en) 2005-06-03
DK0923568T3 (da) 2003-04-07
ES2188983T3 (es) 2003-07-01
ES2188983T4 (es) 2004-06-01
EP0923568B1 (de) 2002-12-11
US6211203B1 (en) 2001-04-03
EP0923568A1 (de) 1999-06-23
JP2000516932A (ja) 2000-12-19
PT923568E (pt) 2003-04-30
DE69717827D1 (de) 2003-01-23
EP0923568B9 (de) 2003-08-13
DK0923568T5 (da) 2003-11-03
AU4454597A (en) 1998-03-06
DE69717827T2 (de) 2003-09-04

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