CY2458B1 - Novel benzofuran-4-carboxamides. - Google Patents

Novel benzofuran-4-carboxamides.

Info

Publication number
CY2458B1
CY2458B1 CY0400046A CY0400046A CY2458B1 CY 2458 B1 CY2458 B1 CY 2458B1 CY 0400046 A CY0400046 A CY 0400046A CY 0400046 A CY0400046 A CY 0400046A CY 2458 B1 CY2458 B1 CY 2458B1
Authority
CY
Cyprus
Prior art keywords
carboxamides
novel benzofuran
benzofuran
novel
substituted
Prior art date
Application number
CY0400046A
Other languages
English (en)
Inventor
Wolf-Ruediger Ulrich
Dieter Flockerzi
Beate Degutterer
Ulrich Thibaut
Armin Hatzelmann
Christian Schudt
Dietrich Haefner
Hans-Peter Kley
Hermann Amschler
Rolf Beume
Original Assignee
Byk Gulden Lomberg Chem Fab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Byk Gulden Lomberg Chem Fab filed Critical Byk Gulden Lomberg Chem Fab
Publication of CY2458B1 publication Critical patent/CY2458B1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Table Devices Or Equipment (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Furan Compounds (AREA)
CY0400046A 1996-08-19 2004-06-08 Novel benzofuran-4-carboxamides. CY2458B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19633052 1996-08-19

Publications (1)

Publication Number Publication Date
CY2458B1 true CY2458B1 (en) 2005-06-03

Family

ID=7802799

Family Applications (1)

Application Number Title Priority Date Filing Date
CY0400046A CY2458B1 (en) 1996-08-19 2004-06-08 Novel benzofuran-4-carboxamides.

Country Status (11)

Country Link
US (1) US6211203B1 (xx)
EP (1) EP0923568B9 (xx)
JP (1) JP4309475B2 (xx)
AT (1) ATE229516T1 (xx)
AU (1) AU4454597A (xx)
CY (1) CY2458B1 (xx)
DE (1) DE69717827T2 (xx)
DK (1) DK0923568T5 (xx)
ES (1) ES2188983T4 (xx)
PT (1) PT923568E (xx)
WO (1) WO1998007715A1 (xx)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ371998A3 (cs) * 1996-05-20 1999-03-17 Darwin Discovery Limited Benzofuranové karboxamidy a jejich terapeutické použití
JP2002502851A (ja) * 1998-02-09 2002-01-29 ダーウィン・ディスカバリー・リミテッド ベンゾフラン−４−カルボキサミドとその治療的使用
TW555759B (en) * 1998-06-08 2003-10-01 Darwin Discovery Ltd Heterocyclic compounds and their therapeutic use
DE59906365D1 (de) * 1998-06-10 2003-08-28 Altana Pharma Ag Benzamide mit tetrahydrofuranyloxy-substituenten als inhibitoren der phosphodiesterase 4
CA2345459A1 (en) * 1998-11-12 2000-05-18 Regine Bohacek Bicyclic signal transduction inhibitors, compositions containing them & uses thereof
DE19924340A1 (de) 1999-05-27 2000-11-30 Basf Ag Verfahren zur selektiven Hydrierung von ethylenisch ungesättigten Doppelbindungen in Polymeren
KR100701904B1 (ko) 1999-08-21 2007-04-02 알타나 파마 아게 Ｐｄｅ 억제제 및 베타 2 아드레날린수용체 작동제의상승적 조합
GB0003257D0 (en) 2000-02-11 2000-04-05 Darwin Discovery Ltd Heterocyclic compounds and their therapeutic use
CA2620333A1 (en) 2005-08-26 2007-03-01 Braincells, Inc. Neurogenesis by muscarinic receptor modulation
EP2258359A3 (en) 2005-08-26 2011-04-06 Braincells, Inc. Neurogenesis by muscarinic receptor modulation with sabcomelin
EP2377530A3 (en) 2005-10-21 2012-06-20 Braincells, Inc. Modulation of neurogenesis by PDE inhibition
WO2007053596A1 (en) 2005-10-31 2007-05-10 Braincells, Inc. Gaba receptor mediated modulation of neurogenesis
US20100216734A1 (en) 2006-03-08 2010-08-26 Braincells, Inc. Modulation of neurogenesis by nootropic agents
US7842713B2 (en) * 2006-04-20 2010-11-30 Pfizer Inc Fused phenyl amido heterocyclic compounds
JP2009536669A (ja) 2006-05-09 2009-10-15 ブレインセルス，インコーポレイティド アンジオテンシン調節による神経新生
EP2026813A2 (en) 2006-05-09 2009-02-25 Braincells, Inc. 5 ht receptor mediated neurogenesis
KR20090064418A (ko) 2006-09-08 2009-06-18 브레인셀즈 인코퍼레이션 4-아실아미노피리딘 유도체 포함 조합물
US20100184806A1 (en) 2006-09-19 2010-07-22 Braincells, Inc. Modulation of neurogenesis by ppar agents
PE20110303A1 (es) 2008-09-11 2011-05-21 Pfizer Derivados de heteroaril acetamidas como activadores de glucoquinasa
AR074760A1 (es) 2008-12-18 2011-02-09 Metabolex Inc Agonistas del receptor gpr120 y usos de los mismos en medicamentos para el tratamiento de diabetes y el sindrome metabolico.
US20100216805A1 (en) 2009-02-25 2010-08-26 Braincells, Inc. Modulation of neurogenesis using d-cycloserine combinations
PT2406253E (pt) 2009-03-11 2013-09-11 Pfizer Derivados de benzofuranilo utilizados como inibidores de glucocinase
RU2446143C2 (ru) * 2010-05-19 2012-03-27 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Ярославский государственный технический университет" (ЯГТУ) Способ получения эфиров замещенных 5,6-дицианобензофуран-2-карбоновых кислот
ES2526124T3 (es) * 2010-06-16 2015-01-07 Cymabay Therapeutics, Inc. Agonistas del receptor GPR120 y sus usos
US8299117B2 (en) 2010-06-16 2012-10-30 Metabolex Inc. GPR120 receptor agonists and uses thereof
US20150119399A1 (en) 2012-01-10 2015-04-30 President And Fellows Of Harvard College Beta-cell replication promoting compounds and methods of their use
US11390614B2 (en) 2017-11-10 2022-07-19 Jiangsu Hengrui Medicine Co., Ltd. Method for preparing benzofuran derivative

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0706513T3 (da) * 1993-07-02 2002-09-09 Altana Pharma Ag Fluoralkoxysubstituerede benzamider og anvendelse deraf som cyklisk-nukleotid phosphodiesteraseinhibitorer
NZ290420A (en) * 1994-07-22 1999-01-28 Byk Gulden Lomberg Chem Fab Phenyl or pyridyl-amide substituted dihydro benzofurans; medicaments
DE69636086T2 (de) * 1995-05-19 2006-11-30 Kyowa Hakko Kogyo Co., Ltd. Sauerstoff enthaltende heterocyclische verbindungen
HUP9903797A3 (en) * 1995-12-05 2001-08-28 Darwin Discovery Ltd Milton Ro Benzofuran carboxamides and sulphonamides, their use for producing medicaments and such medicaments
CZ371998A3 (cs) * 1996-05-20 1999-03-17 Darwin Discovery Limited Benzofuranové karboxamidy a jejich terapeutické použití

Also Published As

Publication number Publication date
DE69717827D1 (de) 2003-01-23
EP0923568B9 (en) 2003-08-13
ES2188983T4 (es) 2004-06-01
JP4309475B2 (ja) 2009-08-05
ATE229516T1 (de) 2002-12-15
WO1998007715A1 (en) 1998-02-26
DK0923568T3 (da) 2003-04-07
DE69717827T2 (de) 2003-09-04
AU4454597A (en) 1998-03-06
WO1998007715A9 (en) 1999-04-29
DK0923568T5 (da) 2003-11-03
EP0923568A1 (en) 1999-06-23
JP2000516932A (ja) 2000-12-19
ES2188983T3 (es) 2003-07-01
EP0923568B1 (en) 2002-12-11
US6211203B1 (en) 2001-04-03
PT923568E (pt) 2003-04-30

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