ATE215540T1 - Benzofuran-carboxamide und -sulfonamide - Google Patents

Benzofuran-carboxamide und -sulfonamide

Info

Publication number
ATE215540T1
ATE215540T1 AT96941138T AT96941138T ATE215540T1 AT E215540 T1 ATE215540 T1 AT E215540T1 AT 96941138 T AT96941138 T AT 96941138T AT 96941138 T AT96941138 T AT 96941138T AT E215540 T1 ATE215540 T1 AT E215540T1
Authority
AT
Austria
Prior art keywords
sulfonamides
benzofuran
benzofuran carboxamides
carboxamides
carboxides
Prior art date
Application number
AT96941138T
Other languages
English (en)
Inventor
Hazel Joan Dyke
Hannah Jayne Kendall
Christopher Lowe
John Gary Montana
Original Assignee
Darwin Discovery Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9524832.4A external-priority patent/GB9524832D0/en
Priority claimed from GBGB9610515.0A external-priority patent/GB9610515D0/en
Priority claimed from GBGB9610712.3A external-priority patent/GB9610712D0/en
Application filed by Darwin Discovery Ltd filed Critical Darwin Discovery Ltd
Application granted granted Critical
Publication of ATE215540T1 publication Critical patent/ATE215540T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/80Radicals substituted by oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/86Benzo [b] furans; Hydrogenated benzo [b] furans with an oxygen atom directly attached in position 7
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
AT96941138T 1995-12-05 1996-12-05 Benzofuran-carboxamide und -sulfonamide ATE215540T1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GBGB9524832.4A GB9524832D0 (en) 1995-12-05 1995-12-05 Novel compounds
GBGB9610515.0A GB9610515D0 (en) 1996-05-20 1996-05-20 Novel compounds
GBGB9610712.3A GB9610712D0 (en) 1995-12-05 1996-05-22 Novel compounds
PCT/GB1996/003012 WO1997020833A1 (en) 1995-12-05 1996-12-05 Benzofuran carboxamides and sulphonamides

Publications (1)

Publication Number Publication Date
ATE215540T1 true ATE215540T1 (de) 2002-04-15

Family

ID=27268015

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96941138T ATE215540T1 (de) 1995-12-05 1996-12-05 Benzofuran-carboxamide und -sulfonamide

Country Status (16)

Country Link
US (1) US5773467A (de)
EP (1) EP0873331B1 (de)
JP (1) JP2000501411A (de)
KR (1) KR19990071894A (de)
CN (1) CN1100773C (de)
AT (1) ATE215540T1 (de)
AU (1) AU697976B2 (de)
BR (1) BR9611897A (de)
CA (1) CA2238376C (de)
CZ (1) CZ292443B6 (de)
DE (1) DE69620458T2 (de)
ES (1) ES2172695T3 (de)
HU (1) HUP9903797A3 (de)
NO (1) NO982570L (de)
PL (1) PL327181A1 (de)
WO (1) WO1997020833A1 (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TR199802386T2 (xx) * 1996-05-20 1999-02-22 Darwin Discovery Limited Benzofuran karboksamidler ve bunlar�n terap�tik kullan�m�.
WO1998007715A1 (de) * 1996-08-19 1998-02-26 Byk Gulden Lomberg Chemische Fabrik Gmbh Novel benzofuran-4-carboxamides
EP1029860B1 (de) * 1997-10-01 2003-04-16 Kyowa Hakko Kogyo Co., Ltd. Benzofuranderivate
AU1983599A (en) * 1998-01-26 1999-08-09 Kyowa Hakko Kogyo Co. Ltd. Oxygenic heterocyclic compounds
CN1290266A (zh) * 1998-02-09 2001-04-04 达尔文发现有限公司 苯并呋喃-4-甲酰胺和其治疗用途
FR2778662B1 (fr) * 1998-05-12 2000-06-16 Adir Nouveaux composes cycliques substitues, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
TW555759B (en) * 1998-06-08 2003-10-01 Darwin Discovery Ltd Heterocyclic compounds and their therapeutic use
ATE245642T1 (de) * 1998-06-10 2003-08-15 Altana Pharma Ag Benzamide mit tetrahydrofuranyloxy-substituenten als inhibitoren der phosphodiesterase 4
SK287231B6 (sk) 1999-08-21 2010-04-07 Nycomed Gmbh Liečivo zahŕňajúce PDE inhibítor a agonistu beta2 adrenoreceptora
US7217722B2 (en) * 2000-02-01 2007-05-15 Kirin Beer Kabushiki Kaisha Nitrogen-containing compounds having kinase inhibitory activity and drugs containing the same
GB0011802D0 (en) * 2000-05-16 2000-07-05 Smithkline Beecham Method for enhancing cognitive function
FR2903106B1 (fr) * 2006-07-03 2010-07-30 Sanofi Aventis Utilisations de 2-benzoyl-imidazopyridines en therapeutique
EP2196465A1 (de) 2008-12-15 2010-06-16 Almirall, S.A. (3-oxo)pyridazin-4-ylurea-Derivate als PDE4 Hemmern
AR074760A1 (es) * 2008-12-18 2011-02-09 Metabolex Inc Agonistas del receptor gpr120 y usos de los mismos en medicamentos para el tratamiento de diabetes y el sindrome metabolico.
EP2226323A1 (de) 2009-02-27 2010-09-08 Almirall, S.A. Neuartige Tetrahydropyrazol[3,4-c]isochinolin-5-amin-Derivate
EP2380890A1 (de) 2010-04-23 2011-10-26 Almirall, S.A. Neue 7,8-Dihydro-1,6-Naphthyridin-5(6H)-on-Derivate als PDE4 Inhibitoren
EP2394998A1 (de) 2010-05-31 2011-12-14 Almirall, S.A. 3-(5-Amino-6-oxo-1,6-dihydropyridazin-3-yl)-biphenyl Derivate als PDE4 Inhibitoren
JP5648058B2 (ja) 2010-07-22 2015-01-07 扶桑薬品工業株式会社 ベンゾフラノン化合物およびそれを含む医薬組成物
WO2016112036A1 (en) 2015-01-05 2016-07-14 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Myc g-quadruplex stabilizing small molecules and their use
CN114149457B (zh) * 2021-11-03 2024-04-12 湖北民族大学 一种苯并[c][1,2]氧杂硼戊环-1(3H)-醇类合物及其用途

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1260947A (en) * 1984-12-29 1989-09-26 Yoshitaka Ohishi Benzofuran derivative, process for preparing the same and pharmaceutical composition containing the same
ES2127966T3 (es) * 1994-05-31 1999-05-01 Bayer Ag Derivados de amino-benzofurilo y -benzotienilo.
US6121274A (en) * 1994-07-22 2000-09-19 Byk Gulden Lomberg Chemische Fabrik Gmbh Dihydrobenzofurane
JP4172817B2 (ja) * 1995-05-19 2008-10-29 協和醗酵工業株式会社 含酸素複素環化合物
TR199802386T2 (xx) * 1996-05-20 1999-02-22 Darwin Discovery Limited Benzofuran karboksamidler ve bunlar�n terap�tik kullan�m�.

Also Published As

Publication number Publication date
KR19990071894A (ko) 1999-09-27
AU697976B2 (en) 1998-10-22
CZ292443B6 (cs) 2003-09-17
CN1100773C (zh) 2003-02-05
PL327181A1 (en) 1998-11-23
NO982570D0 (no) 1998-06-04
HUP9903797A3 (en) 2001-08-28
AU1038697A (en) 1997-06-27
CZ171498A3 (cs) 1998-10-14
EP0873331A1 (de) 1998-10-28
US5773467A (en) 1998-06-30
WO1997020833A1 (en) 1997-06-12
CN1208411A (zh) 1999-02-17
CA2238376A1 (en) 1997-06-12
BR9611897A (pt) 1999-12-28
ES2172695T3 (es) 2002-10-01
DE69620458D1 (de) 2002-05-08
NO982570L (no) 1998-08-04
HUP9903797A2 (hu) 2001-04-28
JP2000501411A (ja) 2000-02-08
CA2238376C (en) 2006-08-15
MX9804466A (es) 1998-12-31
DE69620458T2 (de) 2002-10-02
EP0873331B1 (de) 2002-04-03

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Legal Events

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UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee