DE69122427T2 - Imidazonaphthyridinderivate - Google Patents

Imidazonaphthyridinderivate

Info

Publication number
DE69122427T2
DE69122427T2 DE69122427T DE69122427T DE69122427T2 DE 69122427 T2 DE69122427 T2 DE 69122427T2 DE 69122427 T DE69122427 T DE 69122427T DE 69122427 T DE69122427 T DE 69122427T DE 69122427 T2 DE69122427 T2 DE 69122427T2
Authority
DE
Germany
Prior art keywords
lower alkyl
substituted
represents hydrogen
hydroxy
unsubstituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69122427T
Other languages
English (en)
Other versions
DE69122427D1 (de
Inventor
Fumio Suzuki
Takeshi Kuroda
Shigeto Kitamura
Kenji Ohmori
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KH Neochem Co Ltd
Original Assignee
Kyowa Hakko Kogyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyowa Hakko Kogyo Co Ltd filed Critical Kyowa Hakko Kogyo Co Ltd
Publication of DE69122427D1 publication Critical patent/DE69122427D1/de
Application granted granted Critical
Publication of DE69122427T2 publication Critical patent/DE69122427T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Luminescent Compositions (AREA)
DE69122427T 1990-06-01 1991-05-31 Imidazonaphthyridinderivate Expired - Fee Related DE69122427T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP14346090 1990-06-01
JP33465790 1990-11-30

Publications (2)

Publication Number Publication Date
DE69122427D1 DE69122427D1 (de) 1996-11-07
DE69122427T2 true DE69122427T2 (de) 1997-03-06

Family

ID=26475184

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69122427T Expired - Fee Related DE69122427T2 (de) 1990-06-01 1991-05-31 Imidazonaphthyridinderivate

Country Status (9)

Country Link
US (3) US5364859A (de)
EP (1) EP0459505B1 (de)
JP (1) JP3016905B2 (de)
AT (1) ATE143661T1 (de)
CA (1) CA2043715C (de)
DE (1) DE69122427T2 (de)
DK (1) DK0459505T3 (de)
ES (1) ES2094772T3 (de)
GR (1) GR3021971T3 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0459505T3 (da) * 1990-06-01 1996-11-18 Kyowa Hakko Kogyo Kk Imidazonaphthyridinderivater
JPH05194515A (ja) * 1991-07-31 1993-08-03 Kyowa Hakko Kogyo Co Ltd 縮合ナフチリジン誘導体
US5281610A (en) * 1991-07-31 1994-01-25 Kyowa Hakko Kogyo Co., Ltd. Condensed naphthyridine derivatives
CA2124120A1 (en) * 1991-11-25 1993-06-10 Fumio Suzuki Imidazonaphthyridine derivatives
WO1994002481A1 (en) * 1992-07-20 1994-02-03 Kyowa Hakko Kogyo Co., Ltd. Imidazonaphthyridine derivative
US6365231B2 (en) 1998-06-26 2002-04-02 Kabushiki Kaisha Toshiba Ammonium halide eliminator, chemical vapor deposition system and chemical vapor deposition process
JP2000119271A (ja) * 1998-08-12 2000-04-25 Hokuriku Seiyaku Co Ltd １ｈ―イミダゾピリジン誘導体
AU777012B2 (en) 1999-08-21 2004-09-30 Takeda Gmbh Synergistic combination of PDE inhibitors and beta 2 adrenoceptor agonist
US6949247B2 (en) 2000-12-28 2005-09-27 Unilever Home & Personal Care Usa Division Of Conopco, Inc. Stable skin care compositions containing a retinoid and a retinoid booster system
MXPA03010679A (es) 2001-05-23 2004-03-02 Tanabe Seiyaku Co Una composicion para acelerar la cicatrizacion de fractura osea.
US20040180900A1 (en) 2001-05-23 2004-09-16 Masaharu Takigawa Therapeutic composition for repairing chondropathy
US7087631B2 (en) * 2002-07-18 2006-08-08 Inotek Pharmaceuticals Corporation Aryltetrazole compounds, and compositions thereof
AU2004226353A1 (en) 2003-04-01 2004-10-14 Laboratoires Serono Sa Inhibitors of phosphodiesterases in infertility
CN101268073B (zh) 2005-09-15 2011-10-19 Aska制药株式会社 杂环化合物、制备方法及其用途
EP2367821B1 (de) 2008-12-17 2015-09-16 Merck Patent GmbH Am c-ring modifizierte tricyclische benzonaphthyridinone als proteinkinaseinhibitoren und deren verwendung

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RO66801A (fr) * 1973-05-25 1979-08-15 Lepetit Spa Procede pour obtenir des derives des triazoloizoquinolines
US4059584A (en) * 1974-08-07 1977-11-22 Pfizer 2-Acylamino-3-[3-(dialkylamino)propyl]imidazo[4,5-b]pyridines
CA1271477A (en) * 1983-11-18 1990-07-10 John F. Gerster 1h-imidazo[4,5-c]quinolin-4-amines
ZA848968B (en) * 1983-11-18 1986-06-25 Riker Laboratories Inc 1h-imidazo(4,5-c)quinolines and 1h-imidazo(4,5-c)quinolin-4-amines
IL73534A (en) * 1983-11-18 1990-12-23 Riker Laboratories Inc 1h-imidazo(4,5-c)quinoline-4-amines,their preparation and pharmaceutical compositions containing certain such compounds
US4760073A (en) * 1986-04-11 1988-07-26 Schering Corporation Aryl-substituted naphthyridine and pyridopyrazine derivatives, useful as anti-allergic agents
WO1989000571A2 (en) * 1987-07-22 1989-01-26 Schering Corporation Bicyclic compounds, their use as pharmaceuticals, their preparation, and intermediates useful in their preparation
DK0459505T3 (da) * 1990-06-01 1996-11-18 Kyowa Hakko Kogyo Kk Imidazonaphthyridinderivater

Also Published As

Publication number Publication date
DK0459505T3 (da) 1996-11-18
JP3016905B2 (ja) 2000-03-06
EP0459505A1 (de) 1991-12-04
CA2043715A1 (en) 1991-12-02
CA2043715C (en) 1997-01-07
JPH04226985A (ja) 1992-08-17
GR3021971T3 (en) 1997-03-31
US5364859A (en) 1994-11-15
EP0459505B1 (de) 1996-10-02
US5536730A (en) 1996-07-16
US5468756A (en) 1995-11-21
DE69122427D1 (de) 1996-11-07
ATE143661T1 (de) 1996-10-15
ES2094772T3 (es) 1997-02-01

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee