|
US20120196370A1
(en)
|
2010-12-03 |
2012-08-02 |
Fyodor Urnov |
Methods and compositions for targeted genomic deletion
|
|
US20110239315A1
(en)
|
2009-01-12 |
2011-09-29 |
Ulla Bonas |
Modular dna-binding domains and methods of use
|
|
EP2206723A1
(en)
|
2009-01-12 |
2010-07-14 |
Bonas, Ulla |
Modular DNA-binding domains
|
|
EP2449135B1
(en)
*
|
2009-06-30 |
2016-01-06 |
Sangamo BioSciences, Inc. |
Rapid screening of biologically active nucleases and isolation of nuclease-modified cells
|
|
NO2510096T3
(enExample)
|
2009-12-10 |
2015-03-21 |
|
|
|
US20110203012A1
(en)
*
|
2010-01-21 |
2011-08-18 |
Dotson Stanton B |
Methods and compositions for use of directed recombination in plant breeding
|
|
WO2011100058A1
(en)
*
|
2010-02-09 |
2011-08-18 |
Sangamo Biosciences, Inc. |
Targeted genomic modification with partially single-stranded donor molecules
|
|
EP2563918B1
(en)
*
|
2010-04-26 |
2016-11-23 |
Sangamo BioSciences, Inc. |
Genome editing of a rosa locus using zinc-finger nucleases
|
|
CN103025344B
(zh)
|
2010-05-17 |
2016-06-29 |
桑格摩生物科学股份有限公司 |
新型dna-结合蛋白及其用途
|
|
BR122021005283B1
(pt)
|
2010-06-02 |
2022-02-22 |
Evolva, Inc |
Hospedeiro recombinante que compreende genes recombinantes para produção deesteviol ou glicosídeo de esteviol, método para produzir esteviol, glicosídeo de esteviol ou composição de glicosídeo de esteviol e método para sintetizar esteviol ou glicosídeo de esteviol
|
|
EP2392208B1
(en)
*
|
2010-06-07 |
2016-05-04 |
Helmholtz Zentrum München Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) |
Fusion proteins comprising a DNA-binding domain of a Tal effector protein and a non-specific cleavage domain of a restriction nuclease and their use
|
|
EP2580331A4
(en)
*
|
2010-06-14 |
2013-11-27 |
Univ Iowa State Res Found Inc |
NUCLEASE ACTIVITY OF THE TAL EFFECTOR AND FUSION PROTEIN FOKI
|
|
US8945868B2
(en)
|
2010-07-21 |
2015-02-03 |
Sangamo Biosciences, Inc. |
Methods and compositions for modification of a HLA locus
|
|
US20240397918A1
(en)
*
|
2011-02-25 |
2024-12-05 |
Recombinetics, Inc. |
Non-meiotic allele introgression
|
|
US10920242B2
(en)
|
2011-02-25 |
2021-02-16 |
Recombinetics, Inc. |
Non-meiotic allele introgression
|
|
US9528124B2
(en)
|
2013-08-27 |
2016-12-27 |
Recombinetics, Inc. |
Efficient non-meiotic allele introgression
|
|
CA2828239C
(en)
*
|
2011-02-25 |
2020-10-06 |
Recombinetics, Inc. |
Genetically modified animals and methods for making the same
|
|
KR101982360B1
(ko)
*
|
2011-04-05 |
2019-05-24 |
셀렉티스 |
콤팩트 tale-뉴클레아제의 발생 방법 및 이의 용도
|
|
JP6158170B2
(ja)
|
2011-04-27 |
2017-07-12 |
アミリス, インコーポレイテッド |
ゲノム修飾のための方法
|
|
TR201802544T4
(tr)
|
2011-06-06 |
2018-03-21 |
Bayer Cropscience Nv |
Önceden seçilmiş bir bölgede bir bitki genomunu modifiye için yöntemler ve araçlar.
|
|
CA2841710C
(en)
*
|
2011-07-15 |
2021-03-16 |
The General Hospital Corporation |
Methods of transcription activator like effector assembly
|
|
EP2734621B1
(en)
|
2011-07-22 |
2019-09-04 |
President and Fellows of Harvard College |
Evaluation and improvement of nuclease cleavage specificity
|
|
US9161995B2
(en)
|
2011-07-25 |
2015-10-20 |
Sangamo Biosciences, Inc. |
Methods and compositions for alteration of a cystic fibrosis transmembrane conductance regulator (CFTR) gene
|
|
US9370551B2
(en)
|
2011-07-27 |
2016-06-21 |
The Broad Institute, Inc. |
Compositions and methods of treating head and neck cancer
|
|
EP2737066B1
(en)
*
|
2011-07-29 |
2017-11-08 |
Cellectis |
High throughput method for assembly and cloning polynucleotides comprising highly similar polynucleotidic modules
|
|
WO2013019745A1
(en)
*
|
2011-07-29 |
2013-02-07 |
Georgia Health Sciences University |
Methods and compositions for genetically modifiying cells
|
|
CN102787125B
(zh)
*
|
2011-08-05 |
2013-12-04 |
北京大学 |
一种构建tale重复序列的方法
|
|
BR122021015509B1
(pt)
|
2011-08-08 |
2022-03-29 |
Evolva Sa |
Método para produzir um glicosídeo de esteviol alvo
|
|
BR122014004140B8
(pt)
|
2011-08-22 |
2023-03-28 |
Bayer Cropscience Ag |
Vetor recombinante ou construção recombinante, bem como métodos para obter e produzir uma planta de algodão ou célula vegetal tolerante a um inibidor de hppd, e para cultivar um campo de plantas de algodão
|
|
EP3498833B1
(en)
|
2011-09-21 |
2023-08-16 |
Sangamo Therapeutics, Inc. |
Methods and compositions for regulation of transgene expression
|
|
WO2013050611A1
(en)
|
2011-10-07 |
2013-04-11 |
Basf Plant Science Company Gmbh |
Method of producing plants having increased resistance to pathogens
|
|
WO2013050593A1
(en)
|
2011-10-07 |
2013-04-11 |
Basf Plant Science Company Gmbh |
Method of producing plants having increased resistance to pathogens
|
|
WO2013050318A1
(en)
|
2011-10-07 |
2013-04-11 |
Basf Plant Science Company Gmbh |
Method of producing plants having increased resistance to pathogens
|
|
WO2013053711A1
(en)
|
2011-10-10 |
2013-04-18 |
Basf Plant Science Company Gmbh |
Method of producing plants having increased resistance to pathogens
|
|
WO2013053686A1
(en)
|
2011-10-10 |
2013-04-18 |
Basf Plant Science Company Gmbh |
Method of producing plants having increased resistance to pathogens
|
|
BR112014008895A2
(pt)
|
2011-10-12 |
2019-09-24 |
Bayer Cropscience Ag |
plantas com atividade diminuída de uma enzima de desfosforilação do amido
|
|
BR112014008723A2
(pt)
|
2011-10-12 |
2019-09-24 |
Bayer Cropscience Ag |
plantas com diminuição da atividade de uma enzima de desforilação de àmido
|
|
US9513283B2
(en)
|
2011-10-21 |
2016-12-06 |
Kyushu University, National University Corporation |
Method for designing RNA binding protein utilizing PPR motif, and use thereof
|
|
CA2852955C
(en)
|
2011-10-27 |
2021-02-16 |
Sangamo Biosciences, Inc. |
Methods and compositions for modification of the hprt locus
|
|
MX2014005212A
(es)
|
2011-10-31 |
2014-11-25 |
Pioneer Hi Bred Int |
Mejoramiento de la tolerancia a la sequia, eficiencia de uso de nitrogeno y rendimiento de una planta.
|
|
CA2854819C
(en)
|
2011-11-16 |
2022-07-19 |
Sangamo Biosciences, Inc. |
Modified dna-binding proteins and uses thereof
|
|
US8450107B1
(en)
|
2011-11-30 |
2013-05-28 |
The Broad Institute Inc. |
Nucleotide-specific recognition sequences for designer TAL effectors
|
|
US20130137173A1
(en)
*
|
2011-11-30 |
2013-05-30 |
Feng Zhang |
Nucleotide-specific recognition sequences for designer tal effectors
|
|
US10801017B2
(en)
|
2011-11-30 |
2020-10-13 |
The Broad Institute, Inc. |
Nucleotide-specific recognition sequences for designer TAL effectors
|
|
US8497124B2
(en)
|
2011-12-05 |
2013-07-30 |
Factor Bioscience Inc. |
Methods and products for reprogramming cells to a less differentiated state
|
|
MX354995B
(es)
|
2011-12-05 |
2018-03-27 |
Factor Bioscience Inc |
Metodos y productos para transfeccion de celulas.
|
|
BR112014014105B1
(pt)
|
2011-12-16 |
2023-10-10 |
Targetgene Biotechnologies Ltd |
Método para modificar um sítio-alvo predeterminado no interior de um ácido nucleico genômico ou organelar alvo em uma célula hospedeira eucariótica por um complexo núcleoproteína
|
|
DE102011122267A1
(de)
|
2011-12-23 |
2013-06-27 |
Kws Saat Ag |
Neue aus Pflanzen stammende cis-regulatorische Elemente für die Entwicklung Pathogen-responsiver chimärer Promotoren
|
|
US9688997B2
(en)
|
2011-12-29 |
2017-06-27 |
Iowa State University Research Foundation, Inc. |
Genetically modified plants with resistance to Xanthomonas and other bacterial plant pathogens
|
|
GB201122458D0
(en)
|
2011-12-30 |
2012-02-08 |
Univ Wageningen |
Modified cascade ribonucleoproteins and uses thereof
|
|
EP2612918A1
(en)
|
2012-01-06 |
2013-07-10 |
BASF Plant Science Company GmbH |
In planta recombination
|
|
WO2013136274A1
(en)
|
2012-03-13 |
2013-09-19 |
University Of Guelph |
Myb55 promoter and use thereof
|
|
CA2865531A1
(en)
|
2012-03-13 |
2013-09-19 |
University Of Guelph |
Methods of increasing tolerance to heat stress and amino acid content of plants
|
|
DK2825190T3
(en)
*
|
2012-03-15 |
2017-02-27 |
Cellectis |
REPEAT VARIABLE DIRESTS FOR TARGETING NUCLEOTIDES
|
|
SG11201405956SA
(en)
|
2012-03-23 |
2014-11-27 |
Cellectis |
Method to overcome dna chemical modifications sensitivity of engineered tale dna binding domains
|
|
CN102628037B
(zh)
*
|
2012-03-31 |
2013-07-24 |
西南大学 |
家蚕油蚕基因BmBlos2遗传改造系统及其制备方法和应用
|
|
US20130274129A1
(en)
*
|
2012-04-04 |
2013-10-17 |
Geneart Ag |
Tal-effector assembly platform, customized services, kits and assays
|
|
WO2013158309A2
(en)
|
2012-04-18 |
2013-10-24 |
The Board Of Trustees Of The Leland Stanford Junior University |
Non-disruptive gene targeting
|
|
EP2841581B2
(en)
|
2012-04-23 |
2023-03-08 |
BASF Agricultural Solutions Seed US LLC |
Targeted genome engineering in plants
|
|
SG11201406547YA
(en)
|
2012-04-25 |
2014-11-27 |
Regeneron Pharma |
Nuclease-mediated targeting with large targeting vectors
|
|
EP2841572B1
(en)
|
2012-04-27 |
2019-06-19 |
Duke University |
Genetic correction of mutated genes
|
|
JP6352250B2
(ja)
|
2012-05-02 |
2018-07-04 |
ダウ アグロサイエンシィズ エルエルシー |
リンゴ酸デヒドロゲナーゼの標的改変
|
|
CA2871524C
(en)
*
|
2012-05-07 |
2021-07-27 |
Sangamo Biosciences, Inc. |
Methods and compositions for nuclease-mediated targeted integration of transgenes
|
|
US11120889B2
(en)
|
2012-05-09 |
2021-09-14 |
Georgia Tech Research Corporation |
Method for synthesizing a nuclease with reduced off-site cleavage
|
|
US9834783B2
(en)
|
2012-05-25 |
2017-12-05 |
Eg Crop Science, Inc. |
Dirigent gene EG261 and its orthologs and paralogs and their uses for pathogen resistance in plants
|
|
DK3473707T3
(da)
*
|
2012-05-25 |
2025-03-17 |
Cellectis |
Fremgangsmåder til engineering af allogen og immunsuppressiv resistent t-celle til immunoterapi
|
|
SI3401400T1
(sl)
|
2012-05-25 |
2019-10-30 |
Univ California |
Postopki in sestavki za RNA usmerjeno modifikacijo tarčne DNA in za RNA usmerjeno modulacijo prepisovanja
|
|
US9605274B2
(en)
|
2012-05-25 |
2017-03-28 |
Evolutionary Genomics, Inc. |
Dirigent gene EG261 and its orthologs and paralogs and their uses for pathogen resistance in plants
|
|
US9890364B2
(en)
|
2012-05-29 |
2018-02-13 |
The General Hospital Corporation |
TAL-Tet1 fusion proteins and methods of use thereof
|
|
WO2013182910A2
(en)
*
|
2012-06-05 |
2013-12-12 |
Cellectis |
New transcription activator-like effector (tale) fusion protein
|
|
CA2875945A1
(en)
|
2012-06-07 |
2013-12-12 |
The Children's Hospital Of Philadelphia |
Controlled gene expression methods
|
|
EP2858486A4
(en)
|
2012-06-12 |
2016-04-13 |
Hoffmann La Roche |
METHOD AND COMPOSITIONS FOR GENERATING ALLELES WITH CONDITIONAL KNOCKOUT
|
|
BR112014031260A2
(pt)
|
2012-06-15 |
2019-08-20 |
Du Pont |
métodos e composições que envolvem variantes de als com preferência de substrato nativo
|
|
BR112014031891A2
(pt)
|
2012-06-19 |
2017-08-01 |
Univ Minnesota |
direcionamento genético nas plantas utilizando vírus de dna
|
|
AR091482A1
(es)
*
|
2012-06-21 |
2015-02-04 |
Recombinetics Inc |
Celulas modificadas geneticamente y metodos par su obtencion
|
|
WO2013191769A1
(en)
*
|
2012-06-22 |
2013-12-27 |
Mayo Foundation For Medical Education And Research |
Genome editing
|
|
AU2013285840A1
(en)
|
2012-07-06 |
2015-02-05 |
National Institute Of Agrobiological Sciences |
Wheat with increased grain-bearing number and method for producing same, and chemical for increasing grain-bearing number of wheat
|
|
CA2875618C
(en)
|
2012-07-11 |
2021-04-27 |
Sangamo Biosciences, Inc. |
Methods and compositions for the treatment of lysosomal storage diseases
|
|
US20150104873A1
(en)
*
|
2012-07-11 |
2015-04-16 |
University of Nevada, Las Vegas |
Genome Surgery with Paired, Permeant Endonuclease Construct
|
|
US10883119B2
(en)
|
2012-07-11 |
2021-01-05 |
Sangamo Therapeutics, Inc. |
Methods and compositions for delivery of biologics
|
|
EP2687605A1
(en)
|
2012-07-19 |
2014-01-22 |
Biogemma |
Method for performing homologous recombination
|
|
US20140230083A1
(en)
|
2012-07-24 |
2014-08-14 |
Cellectis |
Modular base-specific nucleic acid binding domains from burkholderia rhizoxinica proteins
|
|
CN105188767A
(zh)
*
|
2012-07-25 |
2015-12-23 |
布罗德研究所有限公司 |
可诱导的dna结合蛋白和基因组干扰工具及其应用
|
|
US10058078B2
(en)
|
2012-07-31 |
2018-08-28 |
Recombinetics, Inc. |
Production of FMDV-resistant livestock by allele substitution
|
|
SG11201500852WA
(en)
|
2012-08-29 |
2015-04-29 |
Sangamo Biosciences Inc |
Methods and compositions for treatment of a genetic condition
|
|
EP2893016B1
(en)
*
|
2012-09-03 |
2019-06-19 |
Cellectis |
Methods for modulating tal specificity
|
|
JP6442406B2
(ja)
|
2012-09-04 |
2018-12-19 |
ザ スクリプス リサーチ インスティテュート |
標的結合特異性を有するキメラポリペプチド
|
|
UA119135C2
(uk)
|
2012-09-07 |
2019-05-10 |
ДАУ АГРОСАЙЄНСІЗ ЕлЕлСі |
Спосіб отримання трансгенної рослини
|
|
UA118090C2
(uk)
|
2012-09-07 |
2018-11-26 |
ДАУ АГРОСАЙЄНСІЗ ЕлЕлСі |
Спосіб інтегрування послідовності нуклеїнової кислоти, що представляє інтерес, у ген fad2 у клітині сої та специфічний для локусу fad2 білок, що зв'язується, здатний індукувати спрямований розрив
|
|
HK1217732A1
(zh)
|
2012-09-07 |
2017-01-20 |
美国陶氏益农公司 |
Fad3性能基因座及相應的能夠誘導靶向斷裂的靶位點特異性結合蛋白
|
|
EP2895620B1
(en)
|
2012-09-11 |
2017-08-02 |
Life Technologies Corporation |
Nucleic acid amplification
|
|
WO2014043143A1
(en)
|
2012-09-11 |
2014-03-20 |
Life Technologies Corporation |
Nucleic acid amplification
|
|
EP3789405A1
(en)
|
2012-10-12 |
2021-03-10 |
The General Hospital Corporation |
Transcription activator-like effector (tale) - lysine-specific demethylase 1 (lsd1) fusion proteins
|
|
EP2914714A4
(en)
*
|
2012-10-30 |
2016-09-21 |
Recombinetics Inc |
CONTROLLING GENDER TREATMENT IN ANIMALS
|
|
US20150291967A1
(en)
|
2012-10-31 |
2015-10-15 |
Luc Mathis |
Coupling herbicide resistance with targeted insertion of transgenes in plants
|
|
KR102315098B1
(ko)
|
2012-11-01 |
2021-10-21 |
팩터 바이오사이언스 인크. |
세포에서 단백질을 발현시키는 방법들과 생성물들
|
|
US20140120578A1
(en)
|
2012-11-01 |
2014-05-01 |
Medicago Inc. |
Plants for production of therapeutic proteins
|
|
EP2922959A4
(en)
*
|
2012-11-20 |
2016-04-20 |
Simplot Co J R |
TAL-MEDIATED TRANSFER DNA INTRODUCTION
|
|
EP2929017A4
(en)
|
2012-12-05 |
2016-09-28 |
Sangamo Biosciences Inc |
METHOD AND COMPOSITIONS FOR REGULATING METABOLISM DISEASES
|
|
EP3138911B1
(en)
|
2012-12-06 |
2018-12-05 |
Sigma Aldrich Co. LLC |
Crispr-based genome modification and regulation
|
|
WO2014093701A1
(en)
|
2012-12-12 |
2014-06-19 |
The Broad Institute, Inc. |
Functional genomics using crispr-cas systems, compositions, methods, knock out libraries and applications thereof
|
|
BR112015013784A2
(pt)
|
2012-12-12 |
2017-07-11 |
Massachusetts Inst Technology |
aplicação, manipulação e otimização de sistemas, métodos e composições para manipulação de sequência e aplicações terapêuticas
|
|
CN103013954B
(zh)
*
|
2012-12-17 |
2014-03-05 |
中国科学院遗传与发育生物学研究所 |
水稻基因badh2的定点敲除系统及其应用
|
|
US9708589B2
(en)
|
2012-12-18 |
2017-07-18 |
Monsanto Technology Llc |
Compositions and methods for custom site-specific DNA recombinases
|
|
EP2934097B1
(en)
*
|
2012-12-21 |
2018-05-02 |
Cellectis |
Potatoes with reduced cold-induced sweetening
|
|
WO2014100525A2
(en)
|
2012-12-21 |
2014-06-26 |
Pioneer Hi-Bred International, Inc. |
Compositions and methods for auxin-analog conjugation
|
|
CN105051195B
(zh)
|
2013-02-06 |
2019-09-06 |
埃沃尔瓦公司 |
用于提高莱鲍迪苷d和莱鲍迪苷m之产生的方法
|
|
EP2954042B1
(en)
*
|
2013-02-07 |
2017-12-06 |
The General Hospital Corporation |
Tale transcriptional activators
|
|
MX2015010098A
(es)
|
2013-02-11 |
2016-04-19 |
Evolva Sa |
Producción eficiente de glicosidos de esteviol en huéspedes recombinantes.
|
|
CN103319574A
(zh)
*
|
2013-02-16 |
2013-09-25 |
清华大学 |
分离的多肽及其应用
|
|
CN109913495B
(zh)
|
2013-02-20 |
2022-11-25 |
瑞泽恩制药公司 |
大鼠的遗传修饰
|
|
US20150353885A1
(en)
|
2013-02-21 |
2015-12-10 |
Cellectis |
Method to counter-select cells or organisms by linking loci to nuclease components
|
|
EP2958996B1
(en)
|
2013-02-25 |
2019-10-16 |
Sangamo Therapeutics, Inc. |
Methods and compositions for enhancing nuclease-mediated gene disruption
|
|
US9393257B2
(en)
*
|
2013-03-01 |
2016-07-19 |
Regents Of The University Of Minnesota |
TALEN-based gene correction
|
|
CN105473721A
(zh)
|
2013-03-11 |
2016-04-06 |
先锋国际良种公司 |
采用磺酰脲类依赖型稳定化结构域的方法和组合物
|
|
BR112015023286A2
(pt)
|
2013-03-14 |
2018-03-06 |
Arzeda Corp |
polipeptídeo recombinante com atividade da dicamba descarboxilase, construto de polinucleotídeo, célula, método de produção de uma célula hospedeira compreendendo um polinucleotídeo heterólogo que codifica um polipeptídeo tendo atividade da dicamba descarboxilase, método para descarboxilar dicamba, um derivado de dicamba ou um metabolito de dicamba, método para a detecção de um polipeptideo e método para a detecção da presença de um polinucleotideo que codifica um polipeptideo tendo atividade da dicamba descarboxilase
|
|
US20140315985A1
(en)
|
2013-03-14 |
2014-10-23 |
Caribou Biosciences, Inc. |
Compositions and methods of nucleic acid-targeting nucleic acids
|
|
EP2970995A1
(en)
|
2013-03-14 |
2016-01-20 |
Pioneer Hi-Bred International, Inc. |
Compositions having dicamba decarboxylase activity and methods of use
|
|
CN105246324B
(zh)
*
|
2013-03-15 |
2018-08-28 |
塞尔克蒂斯股份有限公司 |
通过靶向敲除fad2-1a/1b基因来改良大豆油成分
|
|
WO2014144155A1
(en)
*
|
2013-03-15 |
2014-09-18 |
Regents Of The University Of Minnesota |
Engineering plant genomes using crispr/cas systems
|
|
US11039586B2
(en)
|
2013-03-15 |
2021-06-22 |
Monsanto Technology Llc |
Creation and transmission of megaloci
|
|
US10113162B2
(en)
|
2013-03-15 |
2018-10-30 |
Cellectis |
Modifying soybean oil composition through targeted knockout of the FAD2-1A/1B genes
|
|
WO2014144094A1
(en)
*
|
2013-03-15 |
2014-09-18 |
J.R. Simplot Company |
Tal-mediated transfer dna insertion
|
|
US10793867B2
(en)
|
2013-03-15 |
2020-10-06 |
Monsanto Technology, Llc |
Methods for targeted transgene-integration using custom site-specific DNA recombinases
|
|
US9828582B2
(en)
|
2013-03-19 |
2017-11-28 |
Duke University |
Compositions and methods for the induction and tuning of gene expression
|
|
CN105121650A
(zh)
|
2013-04-02 |
2015-12-02 |
拜尔作物科学公司 |
真核生物中的靶向基因组工程
|
|
UA121197C2
(uk)
|
2013-04-05 |
2020-04-27 |
Доу Агросайенсіс Ллс |
Нуклеаза "цинкові пальці" для модифікацїї гена ahas та спосіб її використання
|
|
CN105008536A
(zh)
*
|
2013-04-16 |
2015-10-28 |
深圳华大基因科技服务有限公司 |
分离的寡核苷酸及其用途
|
|
SG10201808935WA
(en)
|
2013-04-16 |
2018-11-29 |
Regeneron Pharma |
Targeted modification of rat genome
|
|
SG11201508730TA
(en)
|
2013-04-22 |
2015-11-27 |
Univ Kyushu Nat Univ Corp |
Dna-binding protein using ppr motif, and use thereof
|
|
EP2796558A1
(en)
|
2013-04-23 |
2014-10-29 |
Rheinische Friedrich-Wilhelms-Universität Bonn |
Improved gene targeting and nucleic acid carrier molecule, in particular for use in plants
|
|
CN103233004B
(zh)
*
|
2013-04-28 |
2015-04-29 |
新疆农垦科学院 |
一种人工dna分子及检测目标基因表达的方法
|
|
WO2014186435A2
(en)
|
2013-05-14 |
2014-11-20 |
University Of Georgia Research Foundation, Inc. |
Compositions and methods for reducing neointima formation
|
|
CN105531372A
(zh)
|
2013-06-14 |
2016-04-27 |
塞尔克蒂斯股份有限公司 |
植物中非转基因基因组编辑方法
|
|
EP3011033B1
(en)
|
2013-06-17 |
2020-02-19 |
The Broad Institute, Inc. |
Functional genomics using crispr-cas systems, compositions methods, screens and applications thereof
|
|
EP3011030B1
(en)
|
2013-06-17 |
2023-11-08 |
The Broad Institute, Inc. |
Optimized crispr-cas double nickase systems, methods and compositions for sequence manipulation
|
|
DK3011031T3
(da)
|
2013-06-17 |
2020-12-21 |
Broad Inst Inc |
Fremføring og anvendelse af crispr-cas-systemerne, vektorer og sammensætninger til levermålretning og -terapi
|
|
EP2818867A1
(en)
|
2013-06-27 |
2014-12-31 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Antibodies conjugated to at least one nucleic acid molecule and their use in multiplex immuno-detection assays
|
|
US20160369268A1
(en)
*
|
2013-07-01 |
2016-12-22 |
The Board Of Regents Of The University Of Texas System |
Transcription activator-like effector (tale) libraries and methods of synthesis and use
|
|
US10563225B2
(en)
|
2013-07-26 |
2020-02-18 |
President And Fellows Of Harvard College |
Genome engineering
|
|
CA2920253A1
(en)
|
2013-08-02 |
2015-02-05 |
Enevolv, Inc. |
Processes and host cells for genome, pathway, and biomolecular engineering
|
|
US10006011B2
(en)
|
2013-08-09 |
2018-06-26 |
Hiroshima University |
Polypeptide containing DNA-binding domain
|
|
JP5931022B2
(ja)
|
2013-08-09 |
2016-06-08 |
国立大学法人広島大学 |
Dna結合ドメインを含むポリペプチド
|
|
US20150044192A1
(en)
|
2013-08-09 |
2015-02-12 |
President And Fellows Of Harvard College |
Methods for identifying a target site of a cas9 nuclease
|
|
SI3041345T1
(sl)
|
2013-09-04 |
2024-08-30 |
KWS SAAT SE & Co. KGaA |
Rastlina, odporna na helminthosporium turcicum
|
|
DE102013014637A1
(de)
|
2013-09-04 |
2015-03-05 |
Kws Saat Ag |
HELMlNTHOSPORlUM TURClCUM-RESlSTENTE PFLANZE
|
|
US9340800B2
(en)
|
2013-09-06 |
2016-05-17 |
President And Fellows Of Harvard College |
Extended DNA-sensing GRNAS
|
|
IL312865B2
(en)
|
2013-09-11 |
2025-06-01 |
Eagle Biologics Inc |
Liquid protein formulations containing viscosity-lowering agents
|
|
US10526616B2
(en)
*
|
2013-09-23 |
2020-01-07 |
Rensselaer Polytechnic Institute |
Nanoparticle-mediated gene delivery, genomic editing and ligand-targeted modification in various cell populations
|
|
CN105874062B
(zh)
|
2013-10-18 |
2021-07-20 |
先锋国际良种公司 |
草甘膦-n-乙酰转移酶(glyat)序列以及使用方法
|
|
MX388563B
(es)
|
2013-10-25 |
2025-03-20 |
Livestock Improvement Corporation Ltd |
Marcadores geneticos y usos de los mismos.
|
|
US10449254B2
(en)
|
2013-11-03 |
2019-10-22 |
The Regents Of The University Of California |
Ionic liquids for transdermal drug delivery
|
|
EP3862434A1
(en)
|
2013-11-04 |
2021-08-11 |
Dow AgroSciences LLC |
Optimal soybean loci
|
|
UA120503C2
(uk)
|
2013-11-04 |
2019-12-26 |
Дау Агросайєнсиз Елелсі |
Спосіб одержання трансгенної клітини рослини кукурудзи
|
|
MX362066B
(es)
|
2013-11-04 |
2019-01-07 |
Dow Agrosciences Llc |
Loci óptimos de soya.
|
|
UY35812A
(es)
|
2013-11-04 |
2015-05-29 |
Dow Agrosciences Llc |
?loci de maíz óptimos?.
|
|
EP3067419B1
(en)
|
2013-11-06 |
2021-03-17 |
Hiroshima University |
Vector for nucleic acid insertion
|
|
WO2015070062A1
(en)
*
|
2013-11-07 |
2015-05-14 |
Massachusetts Institute Of Technology |
Cell-based genomic recorded accumulative memory
|
|
EP2878667A1
(en)
|
2013-11-29 |
2015-06-03 |
Institut Pasteur |
TAL effector means useful for partial or full deletion of DNA tandem repeats
|
|
CN103710360A
(zh)
*
|
2013-12-03 |
2014-04-09 |
南方医科大学珠江医院 |
提高HepGL肝癌细胞氨基甲酰磷酸合成酶表达的方法
|
|
SMT201800653T1
(it)
|
2013-12-11 |
2019-01-11 |
Regeneron Pharma |
Metodi e composizioni per la modificazione indirizzata a bersaglio di un genoma
|
|
JP6174811B2
(ja)
|
2013-12-11 |
2017-08-02 |
リジェネロン・ファーマシューティカルズ・インコーポレイテッドRegeneron Pharmaceuticals, Inc. |
ゲノムの標的改変のための方法及び組成物
|
|
IL289736B2
(en)
|
2013-12-12 |
2025-09-01 |
Massachusetts Inst Technology |
Administration, use and therapeutic applications of CRISPR–Cas gene editing systems and gene editing preparations
|
|
KR20160089530A
(ko)
|
2013-12-12 |
2016-07-27 |
더 브로드 인스티튜트, 인코퍼레이티드 |
Hbv 및 바이러스 질병 및 질환을 위한 crisprcas 시스템 및 조성물의 전달,용도 및 치료적 적용
|
|
WO2015089351A1
(en)
|
2013-12-12 |
2015-06-18 |
The Broad Institute Inc. |
Compositions and methods of use of crispr-cas systems in nucleotide repeat disorders
|
|
WO2015089486A2
(en)
|
2013-12-12 |
2015-06-18 |
The Broad Institute Inc. |
Systems, methods and compositions for sequence manipulation with optimized functional crispr-cas systems
|
|
WO2015089473A1
(en)
|
2013-12-12 |
2015-06-18 |
The Broad Institute Inc. |
Engineering of systems, methods and optimized guide compositions with new architectures for sequence manipulation
|
|
US20160333063A1
(en)
|
2013-12-13 |
2016-11-17 |
The General Hospital Corporation |
Soluble high molecular weight (hmw) tau species and applications thereof
|
|
WO2015092460A1
(en)
|
2013-12-18 |
2015-06-25 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
New gene mutations for the diagnosis of arthrogryposis multiplex congenita and congenital peripheral neuropathies disease
|
|
AU2014368982B2
(en)
|
2013-12-19 |
2021-03-25 |
Amyris, Inc. |
Methods for genomic integration
|
|
US10233456B2
(en)
*
|
2014-01-30 |
2019-03-19 |
The Board Of Trustees Of The University Of Arkansas |
Method, vectors, cells, seeds and kits for stacking genes into a single genomic site
|
|
RU2714404C2
(ru)
|
2014-01-31 |
2020-02-14 |
Фэктор Байосайенс Инк. |
Способы и продукты для получения и доставки нуклеиновых кислот
|
|
DK3102673T3
(da)
|
2014-02-03 |
2020-07-06 |
Sangamo Therapeutics Inc |
Fremgangsmåder og sammensætninger til behandling af beta-talassæmi
|
|
CN104844696A
(zh)
*
|
2014-02-19 |
2015-08-19 |
北京大学 |
一种转录激活子样效应因子功能蛋白设计、合成及其应用
|
|
TW201538518A
(zh)
|
2014-02-28 |
2015-10-16 |
Dow Agrosciences Llc |
藉由嵌合基因調控元件所賦予之根部特異性表現
|
|
SG11201609211VA
(en)
*
|
2014-03-05 |
2016-12-29 |
Nat Univ Corp Univ Kobe |
Genomic sequence modification method for specifically converting nucleic acid bases of targeted dna sequence, and molecular complex for use in same
|
|
MX392639B
(es)
|
2014-03-21 |
2025-03-24 |
Univ Leland Stanford Junior |
Vectores virales recombinantes para la integración de transgenes
|
|
JP6815986B2
(ja)
|
2014-03-26 |
2021-01-20 |
ユニバーシティ オブ メリーランド, カレッジ パーク |
大型家畜の接合体における標的化ゲノム編集
|
|
WO2015153889A2
(en)
*
|
2014-04-02 |
2015-10-08 |
University Of Florida Research Foundation, Incorporated |
Materials and methods for the treatment of latent viral infection
|
|
US9522936B2
(en)
|
2014-04-24 |
2016-12-20 |
Sangamo Biosciences, Inc. |
Engineered transcription activator like effector (TALE) proteins
|
|
BR112016024945A2
(pt)
|
2014-04-28 |
2017-10-24 |
Recombinetics Inc |
edição de gene multiplex em suínos
|
|
CN104611365B
(zh)
*
|
2014-07-17 |
2017-06-16 |
清华大学 |
利用tale转录抑制子在哺乳动物细胞中模块化构建合成基因线路
|
|
WO2015165275A1
(zh)
*
|
2014-04-30 |
2015-11-05 |
清华大学 |
利用tale转录抑制子在哺乳动物细胞中模块化构建合成基因线路
|
|
WO2015165276A1
(zh)
*
|
2014-04-30 |
2015-11-05 |
清华大学 |
利用tale转录抑制子在哺乳动物细胞中模块化构建合成基因线路的试剂盒
|
|
DE102014106327A1
(de)
|
2014-05-07 |
2015-11-12 |
Universitätsklinikum Hamburg-Eppendorf (UKE) |
TAL-Effektornuklease zum gezielten Knockout des HIV-Korezeptors CCR5
|
|
WO2015172149A1
(en)
|
2014-05-09 |
2015-11-12 |
Yale University |
Hyperbranched polyglycerol-coated particles and methods of making and using thereof
|
|
US11918695B2
(en)
|
2014-05-09 |
2024-03-05 |
Yale University |
Topical formulation of hyperbranched polymer-coated particles
|
|
WO2015175642A2
(en)
|
2014-05-13 |
2015-11-19 |
Sangamo Biosciences, Inc. |
Methods and compositions for prevention or treatment of a disease
|
|
MX385689B
(es)
|
2014-06-06 |
2025-03-18 |
Regeneron Pharma |
Métodos y composiciones para modificar un locus dirigido.
|
|
WO2015188870A1
(en)
|
2014-06-12 |
2015-12-17 |
Sesvanderhave N.V. |
Use of selectable marker gene in sugar beet protoplasts transformation method and system
|
|
US20170121723A1
(en)
|
2014-06-12 |
2017-05-04 |
Sesvanderhave N.V. |
Transformation method of sugar beet protoplasts by talen platform technology
|
|
EP3158072B1
(en)
|
2014-06-20 |
2021-01-13 |
Cellectis |
Potatoes with reduced granule-bound starch synthase
|
|
US9738897B2
(en)
|
2014-06-23 |
2017-08-22 |
Regeneron Pharmaceuticals, Inc. |
Nuclease-mediated DNA assembly
|
|
WO2015200805A2
(en)
|
2014-06-26 |
2015-12-30 |
Regeneron Pharmaceuticals, Inc. |
Methods and compositions for targeted genetic modifications and methods of use
|
|
WO2016000237A1
(en)
|
2014-07-03 |
2016-01-07 |
Pioneer Overseas Corporation |
Plants having enhanced tolerance to insect pests and related constructs and methods involving insect tolerance genes
|
|
WO2016022363A2
(en)
|
2014-07-30 |
2016-02-11 |
President And Fellows Of Harvard College |
Cas9 proteins including ligand-dependent inteins
|
|
BR112017002783A2
(pt)
|
2014-08-11 |
2017-12-19 |
Evolva Sa |
produção de glicosídeos de esteviol em hospedeiros recombinantes
|
|
CN107429241B
(zh)
|
2014-08-14 |
2025-10-24 |
百奥赛图(北京)医药科技股份有限公司 |
Dna敲入系统
|
|
CN105367628B
(zh)
*
|
2014-08-19 |
2019-07-26 |
深圳华大基因农业控股有限公司 |
一对高效编辑水稻waxy基因的talen其识别打靶位点及其应用
|
|
CN105367631B
(zh)
*
|
2014-08-25 |
2019-05-14 |
深圳华大基因科技有限公司 |
一种转录激活子样效应因子核酸酶及其编码基因和应用
|
|
IL292575A
(en)
|
2014-09-07 |
2022-06-01 |
Selecta Biosciences Inc |
Methods and preparations for weakening immune responses by modulating gene expression in an antiviral transfer system
|
|
US10612064B2
(en)
|
2014-09-09 |
2020-04-07 |
Evolva Sa |
Production of steviol glycosides in recombinant hosts
|
|
KR101528812B1
(ko)
*
|
2014-09-18 |
2015-06-15 |
강원대학교산학협력단 |
SETDB1 HMTase 발현 저해방법
|
|
CN105440111B
(zh)
*
|
2014-09-30 |
2019-08-13 |
深圳华大基因研究院 |
一对转录激活子样效应因子核酸酶及其编码序列与应用
|
|
MX391067B
(es)
|
2014-10-01 |
2025-03-21 |
Eagle Biologics Inc |
Formulaciones de polisacáridos y ácido nucleico que contienen agentes de reducción de viscosidad.
|
|
CN104357440B
(zh)
*
|
2014-10-09 |
2017-06-13 |
中山大学 |
一对靶向斑马鱼Forkhead box n1基因的Talen识别序列及其mRNA制备方法
|
|
AU2015330699B2
(en)
|
2014-10-10 |
2021-12-02 |
Editas Medicine, Inc. |
Compositions and methods for promoting homology directed repair
|
|
EP3561052A1
(en)
|
2014-10-15 |
2019-10-30 |
Regeneron Pharmaceuticals, Inc. |
Methods and compositions for generating or maintaining pluripotent cells
|
|
WO2016066671A1
(en)
|
2014-10-29 |
2016-05-06 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Method for treating resistant cancers using progastrin inhibitors
|
|
PT3216867T
(pt)
|
2014-11-04 |
2020-07-16 |
Univ Kobe Nat Univ Corp |
Método para modificar a sequência de genoma para introduzir mutação específica a sequência de adn alvo por reação de remoção de bases, e complexo molecular nele utilizado
|
|
CN107532142A
(zh)
*
|
2014-11-11 |
2018-01-02 |
应用干细胞有限公司 |
使用同源重组改造间充质干细胞
|
|
WO2016077429A1
(en)
|
2014-11-12 |
2016-05-19 |
Recombinetics, Inc. |
Heterozygous modifications of tumor suppressor genes and swine model of neurofibromatosis type 1
|
|
DE102014016667B4
(de)
|
2014-11-12 |
2024-03-07 |
Kws Saat Se |
Haploideninduktoren
|
|
US20160138040A1
(en)
*
|
2014-11-13 |
2016-05-19 |
Cellectis |
Brassica engineered to confer herbicide tolerance
|
|
EP3985115A1
(en)
|
2014-12-12 |
2022-04-20 |
The Broad Institute, Inc. |
Protected guide rnas (pgrnas)
|
|
US20170327834A1
(en)
|
2014-12-15 |
2017-11-16 |
Syngenta Participations Ag |
Pesticidal microrna carriers and use thereof
|
|
MX388784B
(es)
|
2014-12-19 |
2025-03-20 |
Regeneron Pharma |
Métodos y composiciones para la modificación genética dirigida a través de direccionamiento múltiple de una sola etapa.
|
|
CA2969151A1
(en)
|
2014-12-23 |
2016-06-30 |
Syngenta Participations Ag |
Methods and compositions for identifying and enriching for cells comprising site specific genomic modifications
|
|
EP3702456A1
(en)
|
2014-12-24 |
2020-09-02 |
The Broad Institute, Inc. |
Crispr having or associated with destabilization domains
|
|
WO2016118560A1
(en)
*
|
2015-01-20 |
2016-07-28 |
Mayo Foundation For Medical Education And Research |
Methods and materials for assembling nucleic acid constructs
|
|
CN114058582A
(zh)
|
2015-01-26 |
2022-02-18 |
菲特治疗公司 |
用于诱导造血细胞分化的方法和组合物
|
|
CA2973674A1
(en)
|
2015-01-30 |
2016-08-04 |
Evolva Sa |
Production of steviol glycosides in recombinant hosts
|
|
CN107709551A
(zh)
|
2015-02-02 |
2018-02-16 |
塞尔克蒂斯股份有限公司 |
无t‑dna整合的农杆菌介导的基因组修饰
|
|
WO2016124918A1
(en)
|
2015-02-03 |
2016-08-11 |
The Institute Of Genetics And Developmental Biology |
Plants with increased seed size
|
|
WO2016124920A1
(en)
|
2015-02-03 |
2016-08-11 |
The Institute Of Genetics And Developmental Biology |
Rice plants with altered seed phenotype and quality
|
|
WO2016130600A2
(en)
|
2015-02-09 |
2016-08-18 |
Duke University |
Compositions and methods for epigenome editing
|
|
US20180031579A1
(en)
|
2015-02-12 |
2018-02-01 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for predicting the responsiveness of a patient affected with malignant hematological disease to chemotherapy treatment and methods of treatment of such disease
|
|
CA2976376A1
(en)
|
2015-02-13 |
2016-08-18 |
Factor Bioscience Inc. |
Nucleic acid products and methods of administration thereof
|
|
JP6590333B2
(ja)
*
|
2015-02-26 |
2019-10-16 |
学校法人東京理科大学 |
Dna結合ドメイン組込み用ベクターおよびそのセット、融合タンパク質コーディングベクターおよびそのセットならびにその製造方法、デスティネーションベクター、植物細胞用発現ベクターおよびその製造方法、植物細胞用発現ベクター作製用キット、形質転換方法、ならびにゲノム編集方法
|
|
US11261466B2
(en)
|
2015-03-02 |
2022-03-01 |
Sinai Health System |
Homologous recombination factors
|
|
WO2016142427A1
(en)
|
2015-03-10 |
2016-09-15 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Method ank kit for reprogramming somatic cells
|
|
US10604743B2
(en)
|
2015-03-16 |
2020-03-31 |
Dsm Ip Assets B.V. |
UDP-glycosyltransferases
|
|
WO2016155482A1
(zh)
*
|
2015-03-16 |
2016-10-06 |
中国科学院遗传与发育生物学研究所 |
一种利用非遗传物质对植物基因组进行定点改造的方法
|
|
WO2016153305A1
(ko)
*
|
2015-03-26 |
2016-09-29 |
한국생명공학연구원 |
표적 유전자 특이적 핵산 프로브 및 Fok Ι 제한효소 이량체를 이용하여 세포 내에서 표적 유전자를 특이적으로 편집하기 위한 조성물 및 이의 용도
|
|
US11046959B2
(en)
*
|
2015-03-30 |
2021-06-29 |
The Board Of Regents Of The Nevada System Of Higher Education On Behalf Of The University Of Nevada, Las Vegas |
Compositions comprising TALENs and methods of treating HIV
|
|
AU2016243052C1
(en)
|
2015-04-03 |
2022-11-24 |
Dana-Farber Cancer Institute, Inc. |
Composition and methods of genome editing of B-cells
|
|
PT3289080T
(pt)
|
2015-04-30 |
2021-11-19 |
Univ Columbia |
Terapia genética para doenças autossómicas dominantes
|
|
WO2016178207A1
(en)
|
2015-05-04 |
2016-11-10 |
Ramot At Tel-Aviv University Ltd. |
Methods and kits for fragmenting dna
|
|
EP3095870A1
(en)
|
2015-05-19 |
2016-11-23 |
Kws Saat Se |
Methods for the in planta transformation of plants and manufacturing processes and products based and obtainable therefrom
|
|
WO2016205759A1
(en)
|
2015-06-18 |
2016-12-22 |
The Broad Institute Inc. |
Engineering and optimization of systems, methods, enzymes and guide scaffolds of cas9 orthologs and variants for sequence manipulation
|
|
TWI813532B
(zh)
|
2015-06-18 |
2023-09-01 |
美商博得學院股份有限公司 |
降低脱靶效應的crispr酶突變
|
|
ES2594486B1
(es)
|
2015-06-19 |
2017-09-26 |
Biopraxis Research Aie |
Molécula de ácido nucleico, proteína de fusión y método para modificar el material genético de una célula
|
|
US11193131B2
(en)
|
2015-06-30 |
2021-12-07 |
Regents Of The University Of Minnesota |
Haploid inducer line for accelerated genome editing
|
|
AU2016295291A1
(en)
|
2015-07-17 |
2018-02-08 |
Institute Of Genetics And Developmental Biology Chinese Academy Of Sciences |
Wheat plants resistant to powdery mildew
|
|
US20190024073A1
(en)
*
|
2015-07-23 |
2019-01-24 |
Mayo Foundation For Medical Education And Research |
Editing mitochondrial dna
|
|
CA2995067A1
(en)
|
2015-08-07 |
2017-02-16 |
Evolva Sa |
Production of steviol glycosides in recombinant hosts
|
|
EP3337908A4
(en)
|
2015-08-18 |
2019-01-23 |
The Broad Institute, Inc. |
METHOD AND COMPOSITIONS FOR CHANGING THE FUNCTION AND STRUCTURE OF CHROMATIN GRINDING AND / OR DOMAINS
|
|
CA2995582A1
(en)
*
|
2015-08-19 |
2017-02-23 |
Children's Research Institute, Children's National Medical Center |
Compositions and methods for treating graft versus host disease
|
|
US10767173B2
(en)
|
2015-09-09 |
2020-09-08 |
National University Corporation Kobe University |
Method for converting genome sequence of gram-positive bacterium by specifically converting nucleic acid base of targeted DNA sequence, and molecular complex used in same
|
|
US10837024B2
(en)
|
2015-09-17 |
2020-11-17 |
Cellectis |
Modifying messenger RNA stability in plant transformations
|
|
WO2017066497A2
(en)
|
2015-10-13 |
2017-04-20 |
Duke University |
Genome engineering with type i crispr systems in eukaryotic cells
|
|
US11207393B2
(en)
|
2015-10-16 |
2021-12-28 |
President And Fellows Of Harvard College |
Regulatory T cell PD-1 modulation for regulating T cell effector immune responses
|
|
IL258821B
(en)
|
2015-10-23 |
2022-07-01 |
Harvard College |
Nucleobase editors and their uses
|
|
WO2017075261A1
(en)
|
2015-10-27 |
2017-05-04 |
Recombinetics, Inc. |
Engineering of humanized car t-cells and platelets by genetic complementation
|
|
EP3368157B1
(en)
|
2015-10-29 |
2022-06-29 |
Dana-Farber Cancer Institute, Inc. |
Methods for identification, assessment, prevention, and treatment of metabolic disorders using pm20d1 and n-lipidated amino acids
|
|
WO2017079428A1
(en)
|
2015-11-04 |
2017-05-11 |
President And Fellows Of Harvard College |
Site specific germline modification
|
|
ES2953925T3
(es)
|
2015-11-04 |
2023-11-17 |
Fate Therapeutics Inc |
Ingeniería genómica de células pluripotentes
|
|
CN115927199A
(zh)
|
2015-11-04 |
2023-04-07 |
菲特治疗公司 |
用于诱导造血细胞分化的方法和组合物
|
|
US11001622B2
(en)
|
2015-11-19 |
2021-05-11 |
The Brigham And Women's Hospital, Inc. |
Method of treating autoimmune disease with lymphocyte antigen CD5-like (CD5L) protein
|
|
US11220693B2
(en)
|
2015-11-27 |
2022-01-11 |
National University Corporation Kobe University |
Method for converting monocot plant genome sequence in which nucleic acid base in targeted DNA sequence is specifically converted, and molecular complex used therein
|
|
ES2899176T3
(es)
|
2015-11-27 |
2022-03-10 |
Kws Saat Se & Co Kgaa |
Plantas tolerantes a las bajas temperaturas
|
|
AU2016362282B2
(en)
|
2015-11-30 |
2023-03-16 |
Duke University |
Therapeutic targets for the correction of the human dystrophin gene by gene editing and methods of use
|
|
AU2016369490C1
(en)
|
2015-12-18 |
2021-12-23 |
Sangamo Therapeutics, Inc. |
Targeted disruption of the T cell receptor
|
|
JP2018537112A
(ja)
|
2015-12-18 |
2018-12-20 |
サンガモ セラピューティクス, インコーポレイテッド |
Mhc細胞受容体の標的化破壊
|
|
DE102015016445A1
(de)
|
2015-12-21 |
2017-06-22 |
Kws Saat Se |
Restorer-Pflanze
|
|
US11840693B2
(en)
|
2015-12-21 |
2023-12-12 |
KWS SAAT SE & Co. KGaA |
Restorer plants
|
|
DE102015017161A1
(de)
|
2015-12-21 |
2017-06-22 |
Kws Saat Se |
Restorer-Pflanze
|
|
EP3901258A1
(en)
|
2016-01-11 |
2021-10-27 |
The Board of Trustees of the Leland Stanford Junior University |
Chimeric proteins and methods of immunotherapy
|
|
NZ743983A
(en)
|
2016-01-11 |
2025-08-29 |
Univ Leland Stanford Junior |
Chimeric proteins and methods of regulating gene expression
|
|
EP4646936A3
(en)
|
2016-02-02 |
2025-11-19 |
Cellectis |
Modifying soybean oil composition through targeted knockout of the fad3a/b/c genes
|
|
EP3416976A2
(en)
|
2016-02-16 |
2018-12-26 |
Yale University |
Compositions for enhancing targeted gene editing and methods of use thereof
|
|
WO2017143061A1
(en)
|
2016-02-16 |
2017-08-24 |
Yale University |
Compositions and methods for treatment of cystic fibrosis
|
|
CN116763942A
(zh)
|
2016-02-18 |
2023-09-19 |
宾州研究基金会 |
脑内生成gaba能神经元
|
|
EP3417061B1
(en)
|
2016-02-18 |
2022-10-26 |
The Regents of the University of California |
Methods and compositions for gene editing in stem cells
|
|
US20190032088A1
(en)
|
2016-02-26 |
2019-01-31 |
Cellectis |
Micelle based system nuclease encapsulation for in-vivo gene editing
|
|
WO2023150553A1
(en)
|
2022-02-01 |
2023-08-10 |
University Of Rochester |
Gpr17 promoter-based targeting and transduction of glial progenitor cells
|
|
EP3429567B1
(en)
|
2016-03-16 |
2024-01-10 |
The J. David Gladstone Institutes |
Methods and compositions for treating obesity and/or diabetes and for identifying candidate treatment agents
|
|
KR20190080825A
(ko)
|
2016-03-21 |
2019-07-08 |
다나-파버 캔서 인스티튜트 인크. |
T-세포 기능소실 상태-특이적 유전자 발현 조절인자 및 그 용도
|
|
AU2017237912B2
(en)
|
2016-03-23 |
2022-03-10 |
The Regents Of The University Of California |
Methods of treating mitochondrial disorders
|
|
US20190117799A1
(en)
|
2016-04-01 |
2019-04-25 |
The Brigham And Women's Hospital, Inc. |
Stimuli-responsive nanoparticles for biomedical applications
|
|
US20190127713A1
(en)
|
2016-04-13 |
2019-05-02 |
Duke University |
Crispr/cas9-based repressors for silencing gene targets in vivo and methods of use
|
|
WO2017180711A1
(en)
|
2016-04-13 |
2017-10-19 |
Editas Medicine, Inc. |
Grna fusion molecules, gene editing systems, and methods of use thereof
|
|
SG11201808856TA
(en)
|
2016-04-13 |
2018-11-29 |
Evolva Sa |
Production of steviol glycosides in recombinant hosts
|
|
AU2017250295B2
(en)
*
|
2016-04-14 |
2022-08-25 |
Fred Hutchinson Cancer Center |
Compositions and methods to program therapeutic cells using targeted nucleic acid nanocarriers
|
|
US10188749B2
(en)
|
2016-04-14 |
2019-01-29 |
Fred Hutchinson Cancer Research Center |
Compositions and methods to program therapeutic cells using targeted nucleic acid nanocarriers
|
|
EP3429633B1
(en)
|
2016-04-15 |
2021-02-24 |
Cellectis |
A method of engineering drug-specific hypersensitive t-cells for immunotherapy by gene inactivation
|
|
CN107312788B
(zh)
*
|
2016-04-26 |
2020-07-28 |
中国科学院动物研究所 |
一种tale重复序列载体的构建方法
|
|
US11730826B2
(en)
|
2016-05-02 |
2023-08-22 |
Massachusetts Institute Of Technology |
Amphiphilic nanoparticles for delivery of CRISPR based therapy
|
|
CN109312378A
(zh)
|
2016-05-16 |
2019-02-05 |
埃沃尔瓦公司 |
在重组宿主中产生甜菊醇糖苷
|
|
EP4219731A3
(en)
|
2016-05-18 |
2023-08-09 |
Amyris, Inc. |
Compositions and methods for genomic integration of nucleic acids into exogenous landing pads
|
|
CN105950623B
(zh)
*
|
2016-05-19 |
2018-11-30 |
电子科技大学 |
一种用于talen高效构建的双rvd单元模块库及talen构建方法
|
|
CN109476715B
(zh)
|
2016-05-26 |
2023-06-27 |
纽海姆有限公司 |
产无籽果实的植物
|
|
US11293021B1
(en)
|
2016-06-23 |
2022-04-05 |
Inscripta, Inc. |
Automated cell processing methods, modules, instruments, and systems
|
|
EP3474849B1
(en)
|
2016-06-27 |
2025-05-21 |
The Broad Institute, Inc. |
Compositions and methods for detecting and treating diabetes
|
|
US20190359992A1
(en)
|
2016-06-28 |
2019-11-28 |
Cellectis |
Altering expression of gene products in plants through targeted insertion of nucleic acid sequences
|
|
CN105949293B
(zh)
*
|
2016-06-28 |
2019-08-13 |
福建农林大学 |
植物源高效转录激活功能域sac3及应用
|
|
WO2018007263A1
(en)
|
2016-07-06 |
2018-01-11 |
Cellectis |
Sequential gene editing in primary immune cells
|
|
EP4321623A3
(en)
|
2016-07-15 |
2024-05-15 |
Salk Institute for Biological Studies |
Methods and compositions for genome editing in non-dividing cells
|
|
EP4275747A3
(en)
|
2016-07-19 |
2024-01-24 |
Duke University |
Therapeutic applications of cpf1-based genome editing
|
|
US10548302B2
(en)
|
2016-07-29 |
2020-02-04 |
Regeneron Pharmaceuticals, Inc. |
Fibrillin-1 mutations for modeling neonatal progeroid syndrome with congenital lipodystrophy
|
|
KR20250103795A
(ko)
|
2016-08-03 |
2025-07-07 |
프레지던트 앤드 펠로우즈 오브 하바드 칼리지 |
아데노신 핵염기 편집제 및 그의 용도
|
|
CA3033327A1
(en)
|
2016-08-09 |
2018-02-15 |
President And Fellows Of Harvard College |
Programmable cas9-recombinase fusion proteins and uses thereof
|
|
EP4056031A1
(en)
|
2016-08-11 |
2022-09-14 |
The Jackson Laboratory |
Methods and compositions relating to improved human red blood cell survival in genetically modified immunodeficient non-human animals
|
|
US10576167B2
(en)
|
2016-08-17 |
2020-03-03 |
Factor Bioscience Inc. |
Nucleic acid products and methods of administration thereof
|
|
UY40582A
(es)
|
2016-08-17 |
2024-01-15 |
Monsanto Technology Llc |
MÉTODOS, COMPOSICIONES y PLANTAS MEDIANTE LA MANIPULACIÓN DEL METABOLISMO DE GIBERELINA PARA AUMENTAR EL RENDIMIENTO COSECHABLE
|
|
CA3034271A1
(en)
|
2016-08-18 |
2018-02-22 |
Cellectis |
Black-spot resistant potatoes with reduced tuber-specific polyphenol oxidase activity
|
|
WO2018039438A1
(en)
|
2016-08-24 |
2018-03-01 |
President And Fellows Of Harvard College |
Incorporation of unnatural amino acids into proteins using base editing
|
|
IL264792B2
(en)
|
2016-08-24 |
2023-10-01 |
Sangamo Therapeutics Inc |
Engineered target-specific zinc-finger nucleases
|
|
KR102552848B1
(ko)
|
2016-08-29 |
2023-07-06 |
더 리전츠 오브 더 유니버시티 오브 캘리포니아 |
피부 치료를 위한 이온성 약제에 기초한 국소 제형
|
|
CA3035484A1
(en)
|
2016-09-01 |
2018-03-08 |
Cellectis |
Methods for altering amino acid content in plants
|
|
US10960085B2
(en)
|
2016-09-07 |
2021-03-30 |
Sangamo Therapeutics, Inc. |
Modulation of liver genes
|
|
JP7466308B2
(ja)
|
2016-09-20 |
2024-04-12 |
デイナ ファーバー キャンサー インスティチュート,インコーポレイテッド |
Usp10バイオマーカーおよびモジュレーターを用いたamlの同定、評価、予防および処置のための組成物および方法
|
|
US20180084767A1
(en)
|
2016-09-21 |
2018-03-29 |
Recombinetics, Inc. |
Animal models for cardiomyopathy
|
|
US20190225974A1
(en)
|
2016-09-23 |
2019-07-25 |
BASF Agricultural Solutions Seed US LLC |
Targeted genome optimization in plants
|
|
US12499971B2
(en)
|
2016-09-28 |
2025-12-16 |
The Broad Institute, Inc. |
Systematic screening and mapping of regulatory elements in non-coding genomic regions, methods, compositions, and applications thereof
|
|
JP6887492B6
(ja)
|
2016-10-04 |
2021-07-14 |
プレシジョン バイオサイエンシズ,インク. |
遺伝子改変細胞で使用するための共刺激ドメイン
|
|
EP3523319B1
(en)
|
2016-10-10 |
2023-06-28 |
Limagrain Europe |
Nucleic acid encoding sm1 resistance to orange wheat blossom midge and method of use
|
|
WO2018069232A1
(en)
|
2016-10-10 |
2018-04-19 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for predicting the risk of having cardiac hypertrophy
|
|
JP7588390B2
(ja)
|
2016-10-14 |
2024-11-22 |
プレジデント アンド フェローズ オブ ハーバード カレッジ |
核酸塩基エディターのaav送達
|
|
GB201617559D0
(en)
|
2016-10-17 |
2016-11-30 |
University Court Of The University Of Edinburgh The |
Swine comprising modified cd163 and associated methods
|
|
WO2018073391A1
(en)
|
2016-10-19 |
2018-04-26 |
Cellectis |
Targeted gene insertion for improved immune cells therapy
|
|
WO2018073393A2
(en)
|
2016-10-19 |
2018-04-26 |
Cellectis |
Tal-effector nuclease (talen) -modified allogenic cells suitable for therapy
|
|
WO2018081081A1
(en)
|
2016-10-24 |
2018-05-03 |
Javier Gil Humanes |
Multiplex gene targeting in plants
|
|
WO2018076335A1
(en)
|
2016-10-31 |
2018-05-03 |
Institute Of Genetics And Developmental Biology, Chinese Academy Of Sciences |
Compositions and methods for enhancing abiotic stress tolerance
|
|
CN109906030B
(zh)
|
2016-11-04 |
2022-03-18 |
安健基因公司 |
用于产生仅重链抗体的经基因修饰的非人动物和方法
|
|
US11396669B2
(en)
|
2016-11-07 |
2022-07-26 |
Evolva Sa |
Production of steviol glycosides in recombinant hosts
|
|
US12227578B2
(en)
|
2016-11-11 |
2025-02-18 |
The Broad Institute, Inc. |
Modulation of intestinal epithelial cell differentiation, maintenance and/or function through T cell action
|
|
CA3042857A1
(en)
|
2016-11-16 |
2018-05-24 |
Cellectis |
Methods for altering amino acid content in plants through frameshift mutations
|
|
JP6948718B2
(ja)
|
2016-11-28 |
2021-10-13 |
国立大学法人大阪大学 |
ゲノム編集方法
|
|
US10519456B2
(en)
|
2016-12-02 |
2019-12-31 |
Syngenta Participations Ag |
Simultaneous gene editing and haploid induction
|
|
CA3045131A1
(en)
|
2016-12-14 |
2018-06-21 |
Ligandal, Inc. |
Methods and compositions for nucleic acid and protein payload delivery
|
|
US20200085758A1
(en)
|
2016-12-16 |
2020-03-19 |
The Brigham And Women's Hospital, Inc. |
Co-delivery of nucleic acids for simultaneous suppression and expression of target genes
|
|
WO2018119359A1
(en)
|
2016-12-23 |
2018-06-28 |
President And Fellows Of Harvard College |
Editing of ccr5 receptor gene to protect against hiv infection
|
|
WO2018123938A1
(ja)
*
|
2016-12-27 |
2018-07-05 |
国立研究開発法人農業・食品産業技術総合研究機構 |
ゲノム編集植物の作出方法
|
|
CN110121336A
(zh)
|
2017-01-05 |
2019-08-13 |
弗莱德哈钦森癌症研究中心 |
改善疫苗功效的系统和方法
|
|
GB201700380D0
(en)
|
2017-01-10 |
2017-02-22 |
Plant Bioscience Ltd |
Methods of increasing seed yield
|
|
RU2019126483A
(ru)
|
2017-01-23 |
2021-02-24 |
Ридженерон Фармасьютикалз, Инк. |
Варианты 17-бета-гидроксистероиддегидрогеназы 13 (hsd17b13) и их применение
|
|
US12344826B2
(en)
|
2017-01-25 |
2025-07-01 |
The George Washington University, A Congressionally Chartered Not-For-Profit Corporation |
Apparatus and methods for in vitro preclinical human trials
|
|
WO2018146481A1
(en)
|
2017-02-09 |
2018-08-16 |
Fujian Agriculture And Forestry University |
Expression of a phosphate transporter for improving plant yield
|
|
JP2020508056A
(ja)
|
2017-02-22 |
2020-03-19 |
クリスパー・セラピューティクス・アクチェンゲゼルシャフトCRISPR Therapeutics AG |
遺伝子編集のための組成物および方法
|
|
EP3366778A1
(de)
|
2017-02-28 |
2018-08-29 |
Kws Saat Se |
Haploidisierung in sorghum
|
|
BR112019018200B1
(pt)
|
2017-03-03 |
2024-02-20 |
Pioneer Hi-Bred International, Inc |
Método para medir a quantidade de um sucrosil-oligossacarídeo,método para medir estaquiose, método para processar sementes de soja geneticamente modificadas
|
|
CN110662556A
(zh)
|
2017-03-09 |
2020-01-07 |
哈佛大学的校长及成员们 |
癌症疫苗
|
|
WO2018165504A1
(en)
|
2017-03-09 |
2018-09-13 |
President And Fellows Of Harvard College |
Suppression of pain by gene editing
|
|
JP2020510439A
(ja)
|
2017-03-10 |
2020-04-09 |
プレジデント アンド フェローズ オブ ハーバード カレッジ |
シトシンからグアニンへの塩基編集因子
|
|
JP7623785B2
(ja)
|
2017-03-21 |
2025-01-29 |
ザ ジャクソン ラボラトリー |
ヒトAPOE4およびマウスTrem2 p.R47Hを発現する遺伝子改変されたマウス、ならびにその使用の方法
|
|
CA3057432C
(en)
|
2017-03-22 |
2023-08-08 |
National University Corporation Kobe University |
Method for converting nucleic acid sequence of cell specifically converting nucleic acid base of targeted dna using cell endogenous dna modifying enzyme, and molecular complex used therein
|
|
BR112019019655A2
(pt)
|
2017-03-23 |
2020-04-22 |
Harvard College |
editores de nucleobase que compreendem proteínas de ligação a dna programáveis por ácido nucleico
|
|
US10980779B2
(en)
|
2017-03-24 |
2021-04-20 |
Inserm (Institut National De La Sante Et De La Recherche Medicale) |
GFI1 inhibitors for the treatment of hyperglycemia
|
|
CA3057759A1
(en)
|
2017-03-24 |
2018-09-27 |
Institute Of Genetics And Developmental Biology, Chinese Academy Of Sciences |
Methods for increasing grain yield
|
|
US12161694B2
(en)
|
2017-03-24 |
2024-12-10 |
The Broad Institute, Inc. |
Methods and compositions for regulating innate lymphoid cell inflammatory responses
|
|
US11542497B2
(en)
|
2017-03-30 |
2023-01-03 |
The University Of Tokyo |
Method for evaluating multiple different genes of interest
|
|
US11963966B2
(en)
|
2017-03-31 |
2024-04-23 |
Dana-Farber Cancer Institute, Inc. |
Compositions and methods for treating ovarian tumors
|
|
US20200113821A1
(en)
|
2017-04-04 |
2020-04-16 |
Yale University |
Compositions and methods for in utero delivery
|
|
US20200071773A1
(en)
|
2017-04-12 |
2020-03-05 |
Massachusetts Eye And Ear Infirmary |
Tumor signature for metastasis, compositions of matter methods of use thereof
|
|
WO2018191520A1
(en)
|
2017-04-12 |
2018-10-18 |
The Broad Institute, Inc. |
Respiratory and sweat gland ionocytes
|
|
EP3392339A1
(en)
|
2017-04-18 |
2018-10-24 |
Rheinisch-Westfälische Technische Hochschule (RWTH) Aachen |
Improved genome editing in plant cells
|
|
CN111031790A
(zh)
|
2017-04-20 |
2020-04-17 |
E开创生物技术股份有限公司 |
产生基因修改的动物的方法
|
|
WO2018195486A1
(en)
|
2017-04-21 |
2018-10-25 |
The Broad Institute, Inc. |
Targeted delivery to beta cells
|
|
HUE067206T2
(hu)
|
2017-04-25 |
2024-10-28 |
Cellectis |
Csökkent ligninösszetételû lucerna
|
|
ES2981244T3
(es)
|
2017-04-28 |
2024-10-07 |
Acuitas Therapeutics Inc |
Novedosas formulaciones de nanopartículas de lípidos de carbonilo y lípidos para la administración de ácidos nucleicos
|
|
CA3059793A1
(en)
|
2017-05-03 |
2018-11-08 |
Sangamo Therapeutics, Inc. |
Methods and compositions for modification of a cystic fibrosis transmembrane conductance regulator (cftr) gene
|
|
WO2018204777A2
(en)
|
2017-05-05 |
2018-11-08 |
The Broad Institute, Inc. |
Methods for identification and modification of lncrna associated with target genotypes and phenotypes
|
|
WO2018208837A1
(en)
|
2017-05-08 |
2018-11-15 |
Precision Biosciences, Inc. |
Nucleic acid molecules encoding an engineered antigen receptor and an inhibitory nucleic acid molecule and methods of use thereof
|
|
WO2018209324A2
(en)
|
2017-05-11 |
2018-11-15 |
The Broad Institute, Inc. |
Methods and compositions of use of cd8+ tumor infiltrating lymphocyte subtypes and gene signatures thereof
|
|
WO2018209320A1
(en)
|
2017-05-12 |
2018-11-15 |
President And Fellows Of Harvard College |
Aptazyme-embedded guide rnas for use with crispr-cas9 in genome editing and transcriptional activation
|
|
RU2019140867A
(ru)
|
2017-05-12 |
2021-06-15 |
Зе Джексон Лаборатори |
Nsg мыши, не имеющие mhc класса i и класса ii
|
|
WO2018211032A1
(en)
|
2017-05-17 |
2018-11-22 |
Evolva Sa |
Production of steviol glycosides in recombinant hosts
|
|
CA3064817A1
(en)
|
2017-05-25 |
2018-11-29 |
Institute Of Genetics And Developmental Biology Chinese Academy Of Sciences |
Methods for increasing grain productivity
|
|
EP3409104A1
(en)
|
2017-05-31 |
2018-12-05 |
Vilmorin et Cie |
Tomato plant resistant to tomato yellow leaf curl virus, powdery mildew, and nematodes
|
|
EP3409106A1
(en)
|
2017-06-01 |
2018-12-05 |
Vilmorin et Cie |
Tolerance in plants of solanum lycopersicum to the tobamovirus tomato brown rugose fruit virus (tbrfv)
|
|
WO2020249996A1
(en)
|
2019-06-14 |
2020-12-17 |
Vilmorin & Cie |
Resistance in plants of solanum lycopersicum to the tobamovirus tomato brown rugose fruit virus
|
|
US11879128B2
(en)
|
2017-06-05 |
2024-01-23 |
Consejo Superior De Investigaciones Científicas (Csic)—Delegación Andalucía |
Targeting of gluten by genome editing
|
|
CN110997906B
(zh)
|
2017-06-05 |
2024-05-07 |
雷杰纳荣制药公司 |
B4galt1变体及其用途
|
|
WO2018226685A2
(en)
|
2017-06-06 |
2018-12-13 |
Dana-Farber Cancer Institute, Inc. |
Methods for sensitizing cancer cells to t cell-mediated killing by modulating molecular pathways
|
|
WO2018231999A1
(en)
|
2017-06-13 |
2018-12-20 |
Regents Of The University Of Minnesota |
Materials and methods for increasing gene editing frequency
|
|
US11897953B2
(en)
|
2017-06-14 |
2024-02-13 |
The Broad Institute, Inc. |
Compositions and methods targeting complement component 3 for inhibiting tumor growth
|
|
US20200362355A1
(en)
|
2017-06-15 |
2020-11-19 |
The Regents Of The University Of California |
Targeted non-viral dna insertions
|
|
US11512287B2
(en)
|
2017-06-16 |
2022-11-29 |
Sangamo Therapeutics, Inc. |
Targeted disruption of T cell and/or HLA receptors
|
|
US20210139870A1
(en)
|
2017-06-19 |
2021-05-13 |
Cellectis |
Anti-hbv combination therapies involving specific endonucleases
|
|
PL3538645T3
(pl)
|
2017-06-20 |
2021-11-08 |
Institut Curie |
Komórki odpornościowe z defektem suv39h1
|
|
US10011849B1
(en)
|
2017-06-23 |
2018-07-03 |
Inscripta, Inc. |
Nucleic acid-guided nucleases
|
|
CA3067842C
(en)
|
2017-06-23 |
2025-11-04 |
University Of Kentucky Research Foundation |
METHODS FOR MODULATING THE ALKALOID CONTENT OF A PLANT OR PART OF THAT PLANT
|
|
US9982279B1
(en)
|
2017-06-23 |
2018-05-29 |
Inscripta, Inc. |
Nucleic acid-guided nucleases
|
|
CA3064601A1
(en)
|
2017-06-26 |
2019-01-03 |
The Broad Institute, Inc. |
Crispr/cas-adenine deaminase based compositions, systems, and methods for targeted nucleic acid editing
|
|
WO2019005957A1
(en)
|
2017-06-30 |
2019-01-03 |
Precision Biosciences, Inc. |
GENETICALLY MODIFIED T CELLS COMPRISING A MODIFIED INTRON IN THE ALPHA T CELL RECEPTOR GENE
|
|
CA3066253C
(en)
|
2017-06-30 |
2023-10-31 |
Inscripta, Inc. |
Automated cell processing methods, modules, instruments, and systems
|
|
CN111094573A
(zh)
*
|
2017-07-12 |
2020-05-01 |
梅约医学教育与研究基金会 |
有效靶向敲入或基因置换的材料和方法
|
|
US12049643B2
(en)
|
2017-07-14 |
2024-07-30 |
The Broad Institute, Inc. |
Methods and compositions for modulating cytotoxic lymphocyte activity
|
|
US12105089B2
(en)
|
2017-07-17 |
2024-10-01 |
The Broad Institute, Inc. |
Cell atlas of the healthy and ulcerative colitis human colon
|
|
JP2020534795A
(ja)
|
2017-07-28 |
2020-12-03 |
プレジデント アンド フェローズ オブ ハーバード カレッジ |
ファージによって支援される連続的進化(pace)を用いて塩基編集因子を進化させるための方法および組成物
|
|
CN111278848B
(zh)
*
|
2017-08-04 |
2023-06-27 |
北京大学 |
特异性识别甲基化修饰dna碱基的tale rvd及其应用
|
|
US20190045761A1
(en)
|
2017-08-11 |
2019-02-14 |
Recombinetics, Inc. |
Inducible disease models methods of making them and use in tissue complementation
|
|
CN111263810A
(zh)
|
2017-08-22 |
2020-06-09 |
纳匹基因公司 |
使用多核苷酸指导的核酸内切酶的细胞器基因组修饰
|
|
EP3447134B1
(en)
|
2017-08-22 |
2023-10-11 |
KWS SAAT SE & Co. KGaA |
Increased fungal resistance in crop plants
|
|
WO2019038417A1
(en)
|
2017-08-25 |
2019-02-28 |
Institute Of Genetics And Developmental Biology, Chinese Academy Of Sciences |
METHODS FOR INCREASING GRAIN YIELD
|
|
US10738327B2
(en)
|
2017-08-28 |
2020-08-11 |
Inscripta, Inc. |
Electroporation cuvettes for automation
|
|
HRP20250980T1
(hr)
|
2017-08-29 |
2025-10-24 |
KWS SAAT SE & Co. KGaA |
Unaprijeđeni sistem plavog aleurona i drugi sistemi segregacije
|
|
US11319532B2
(en)
|
2017-08-30 |
2022-05-03 |
President And Fellows Of Harvard College |
High efficiency base editors comprising Gam
|
|
BR112020005217A2
(pt)
|
2017-09-18 |
2020-09-15 |
Amyris, Inc. |
métodos para a engenharia genética de células hospedeiras de kluyveromyces
|
|
BR112020005166A2
(pt)
|
2017-09-18 |
2020-09-24 |
Amyris, Inc. |
métodos para integração genômica para células hospedeiras de kluyveromyces
|
|
WO2019060759A1
(en)
|
2017-09-21 |
2019-03-28 |
Dana-Farber Cancer Institute, Inc. |
ISOLATION, PRESERVATION, COMPOSITIONS AND USES OF PLANT EXTRACTS JUSTICIA
|
|
EP3585162B1
(en)
|
2017-09-29 |
2023-08-30 |
Regeneron Pharmaceuticals, Inc. |
Rodents comprising a humanized ttr locus and methods of use
|
|
WO2019068022A1
(en)
|
2017-09-30 |
2019-04-04 |
Inscripta, Inc. |
CONTINUOUS FLOW ELECTROPORATION INSTRUMENTATION
|
|
US20200239544A1
(en)
|
2017-10-03 |
2020-07-30 |
Precision Biosciences, Inc. |
Modified epidermal growth factor receptor peptides for use in genetically-modified cells
|
|
US20200255828A1
(en)
|
2017-10-04 |
2020-08-13 |
The Broad Institute, Inc. |
Methods and compositions for altering function and structure of chromatin loops and/or domains
|
|
AU2018347583A1
(en)
|
2017-10-13 |
2020-05-21 |
Selecta Biosciences, Inc. |
Methods and compositions for attenuating anti-viral transfer vector IgM responses
|
|
KR20250107288A
(ko)
|
2017-10-16 |
2025-07-11 |
더 브로드 인스티튜트, 인코퍼레이티드 |
아데노신 염기 편집제의 용도
|
|
AU2018353112B2
(en)
|
2017-10-19 |
2024-11-14 |
Cellectis |
Targeted gene integration of NK inhibitors genes for improved immune cells therapy
|
|
IL274179B2
(en)
|
2017-10-27 |
2024-02-01 |
Univ California |
Targeted replacement of endogenous T cell receptors
|
|
CA3080454A1
(en)
|
2017-10-31 |
2019-05-09 |
Vilmorin & Cie |
Wheat comprising male fertility restorer alleles
|
|
EP3704238B1
(en)
|
2017-11-01 |
2024-01-03 |
Precision Biosciences, Inc. |
Engineered nucleases that target human and canine factor viii genes as a treatment for hemophilia a
|
|
US12018080B2
(en)
|
2017-11-13 |
2024-06-25 |
The Broad Institute, Inc. |
Methods and compositions for treating cancer by targeting the CLEC2D-KLRB1 pathway
|
|
WO2019094955A1
(en)
|
2017-11-13 |
2019-05-16 |
The Broad Institute, Inc. |
Methods and compositions for targeting developmental and oncogenic programs in h3k27m gliomas
|
|
WO2019094984A1
(en)
|
2017-11-13 |
2019-05-16 |
The Broad Institute, Inc. |
Methods for determining spatial and temporal gene expression dynamics during adult neurogenesis in single cells
|
|
EP3713644B1
(en)
|
2017-11-20 |
2024-08-07 |
University of Georgia Research Foundation, Inc. |
Compositions and methods for modulating hif-2a to improve muscle generation and repair
|
|
WO2019106163A1
(en)
|
2017-12-01 |
2019-06-06 |
Cellectis |
Reprogramming of genetically engineered primary immune cells
|
|
WO2019118949A1
(en)
|
2017-12-15 |
2019-06-20 |
The Broad Institute, Inc. |
Systems and methods for predicting repair outcomes in genetic engineering
|
|
WO2019118893A1
(en)
|
2017-12-15 |
2019-06-20 |
Dana-Farber Cancer Institute, Inc. |
Stabilized peptide-mediated targeted protein degradation
|
|
EP3728587A4
(en)
|
2017-12-18 |
2022-01-26 |
Syngenta Participations Ag |
SITES FOR TARGETED INSERTION IN THE MAIZE GENOME
|
|
ES3037765T3
(en)
|
2017-12-22 |
2025-10-07 |
Fate Therapeutics Inc |
Enhanced immune effector cells and use thereof
|
|
EP3501268B1
(en)
|
2017-12-22 |
2021-09-15 |
KWS SAAT SE & Co. KGaA |
Regeneration of plants in the presence of histone deacetylase inhibitors
|
|
CN107868123B
(zh)
|
2017-12-25 |
2020-05-12 |
中国农业科学院作物科学研究所 |
一种同时提高植物产量和抗性的基因及其应用
|
|
EP3508581A1
(en)
|
2018-01-03 |
2019-07-10 |
Kws Saat Se |
Regeneration of genetically modified plants
|
|
US11994512B2
(en)
|
2018-01-04 |
2024-05-28 |
Massachusetts Institute Of Technology |
Single-cell genomic methods to generate ex vivo cell systems that recapitulate in vivo biology with improved fidelity
|
|
BR112020014168A2
(pt)
|
2018-01-12 |
2020-12-08 |
Basf Se |
Proteína, ácido nucleico isolado, gene recombinante, vetor, célula hospedeira, planta, parte de planta ou semente de trigo, métodos para produzir, produto de trigo, farinha, farelo integral, amido, grânulos de amido ou farelo de trigo e métodos para identificar e/ou selecionar uma planta de trigo
|
|
CN111818794A
(zh)
|
2018-02-14 |
2020-10-23 |
中国科学院遗传与发育生物学研究所 |
增加营养物利用效率的方法
|
|
BR112020015486A2
(pt)
|
2018-02-15 |
2020-12-08 |
Monsanto Technology Llc |
Métodos melhorados para a produção de semente de milho híbrido
|
|
UY38095A
(es)
|
2018-02-15 |
2019-10-01 |
Monsanto Technology Llc |
Composiciones y métodos para mejorar los rendimientos de cultivos mediante el apilamiento de rasgos
|
|
KR20200139679A
(ko)
|
2018-02-26 |
2020-12-14 |
안톨알엑스, 인크. |
면역관용성 리포솜 및 그의 사용 방법
|
|
EP3765622B1
(en)
|
2018-03-12 |
2025-04-23 |
Pioneer Hi-Bred International, Inc. |
Methods for plant transformation
|
|
EP4186921A1
(en)
|
2018-03-23 |
2023-05-31 |
The Trustees of Columbia University in the City of New York |
Gene editing for autosomal dominant diseases
|
|
WO2019189147A1
(ja)
|
2018-03-26 |
2019-10-03 |
国立大学法人神戸大学 |
細胞の有する二本鎖dnaの標的部位を改変する方法
|
|
EP3545756A1
(en)
|
2018-03-28 |
2019-10-02 |
KWS SAAT SE & Co. KGaA |
Regeneration of plants in the presence of inhibitors of the histone methyltransferase ezh2
|
|
EP3749762A1
(en)
|
2018-03-29 |
2020-12-16 |
Cellectis |
Tale-nucleases for allele-specific codon modification
|
|
AU2019241967A1
(en)
|
2018-03-29 |
2020-11-19 |
Inscripta, Inc. |
Automated control of cell growth rates for induction and transformation
|
|
CA3093020A1
(en)
|
2018-03-29 |
2019-10-03 |
Fate Therapeutics, Inc. |
Engineered immune effector cells and use thereof
|
|
WO2019195738A1
(en)
|
2018-04-06 |
2019-10-10 |
Children's Medical Center Corporation |
Compositions and methods for somatic cell reprogramming and modulating imprinting
|
|
US12103972B2
(en)
|
2018-04-06 |
2024-10-01 |
Dana-Farber Cancer Institute, Inc. |
KIR3DL3 as an HHLA2 receptor, anti-HHLA2 antibodies, and uses thereof
|
|
GB201805865D0
(en)
|
2018-04-09 |
2018-05-23 |
Innes John Centre |
Genes
|
|
US10376889B1
(en)
|
2018-04-13 |
2019-08-13 |
Inscripta, Inc. |
Automated cell processing instruments comprising reagent cartridges
|
|
US11981892B2
(en)
|
2018-04-16 |
2024-05-14 |
University Of Massachusetts |
Compositions and methods for improved gene editing
|
|
WO2019204643A2
(en)
|
2018-04-18 |
2019-10-24 |
Altius Institute For Biomedical Sciences |
Animal pathogen-derived polypeptides and uses thereof for genetic engineering
|
|
US10508273B2
(en)
|
2018-04-24 |
2019-12-17 |
Inscripta, Inc. |
Methods for identifying selective binding pairs
|
|
US10858761B2
(en)
|
2018-04-24 |
2020-12-08 |
Inscripta, Inc. |
Nucleic acid-guided editing of exogenous polynucleotides in heterologous cells
|
|
US10557216B2
(en)
|
2018-04-24 |
2020-02-11 |
Inscripta, Inc. |
Automated instrumentation for production of T-cell receptor peptide libraries
|
|
DK3560330T3
(da)
|
2018-04-24 |
2022-07-11 |
Kws Saat Se & Co Kgaa |
Planter med forbedret fordøjelighed og markørhaplotyper
|
|
TWI686477B
(zh)
*
|
2018-04-25 |
2020-03-01 |
國立成功大學 |
特異性造成植物葉綠體基因變異的轉殖載體、套組、方法及利用其產生之轉殖植物細胞與農桿菌
|
|
US11957695B2
(en)
|
2018-04-26 |
2024-04-16 |
The Broad Institute, Inc. |
Methods and compositions targeting glucocorticoid signaling for modulating immune responses
|
|
WO2019210268A2
(en)
|
2018-04-27 |
2019-10-31 |
The Broad Institute, Inc. |
Sequencing-based proteomics
|
|
CA3099102C
(en)
|
2018-05-02 |
2024-05-14 |
Cellectis |
Engineering wheat with increased dietary fiber
|
|
US20210386829A1
(en)
|
2018-05-04 |
2021-12-16 |
The Broad Institute, Inc. |
Compositions and methods for modulating cgrp signaling to regulate innate lymphoid cell inflammatory responses
|
|
EP3567111B1
(en)
|
2018-05-09 |
2025-07-09 |
KWS SAAT SE & Co. KGaA |
Gene for resistance to a pathogen of the genus heterodera
|
|
EP3790629A1
(en)
|
2018-05-11 |
2021-03-17 |
CRISPR Therapeutics AG |
Methods and compositions for treating cancer
|
|
GB201808424D0
(en)
|
2018-05-23 |
2018-07-11 |
Lucite Int Uk Ltd |
Methods for producing BMA and MMA using genetically modified microorganisms
|
|
WO2019226953A1
(en)
|
2018-05-23 |
2019-11-28 |
The Broad Institute, Inc. |
Base editors and uses thereof
|
|
US20210371932A1
(en)
|
2018-06-01 |
2021-12-02 |
Massachusetts Institute Of Technology |
Methods and compositions for detecting and modulating microenvironment gene signatures from the csf of metastasis patients
|
|
GB201809273D0
(en)
|
2018-06-06 |
2018-07-25 |
Vib Vzw |
Novel mutant plant cinnamoyl-coa reductase proteins
|
|
CN112424365A
(zh)
|
2018-06-07 |
2021-02-26 |
以色列国家农业部、农村发展农业研究组织·沃尔卡尼中心 |
核酸构建体及其使用方法
|
|
AU2019282761B2
(en)
|
2018-06-07 |
2024-01-04 |
The Brigham And Women's Hospital, Inc. |
Methods for generating hematopoietic stem cells
|
|
IL279271B2
(en)
|
2018-06-07 |
2025-05-01 |
The State Of Israel Ministry Of Agriculture & Rural Development Agricultural Res Organization Aro Vo |
Methods for Cannabis Regeneration and Transformation
|
|
US12036240B2
(en)
|
2018-06-14 |
2024-07-16 |
The Broad Institute, Inc. |
Compositions and methods targeting complement component 3 for inhibiting tumor growth
|
|
AU2019285082B2
(en)
|
2018-06-15 |
2024-09-19 |
KWS SAAT SE & Co. KGaA |
Methods for enhancing genome engineering efficiency
|
|
CA3103500A1
(en)
|
2018-06-15 |
2019-12-19 |
KWS SAAT SE & Co. KGaA |
Methods for improving genome engineering and regeneration in plant ii
|
|
EP3806619A1
(en)
|
2018-06-15 |
2021-04-21 |
Nunhems B.V. |
Seedless watermelon plants comprising modifications in an abc transporter gene
|
|
CN112566924B
(zh)
|
2018-06-15 |
2024-10-29 |
科沃施种子欧洲股份两合公司 |
改善植物中基因组工程化和再生的方法
|
|
WO2019246483A1
(en)
|
2018-06-21 |
2019-12-26 |
The Jackson Laboratory |
Genetically modified mouse models of alzheimer's disease
|
|
WO2020006112A1
(en)
|
2018-06-26 |
2020-01-02 |
Regents Of The University Of Minnesota |
Delivery of developmental regulators to plants for the induction of meristematic tissue with genetic alterations
|
|
EP3814493A4
(en)
|
2018-06-27 |
2022-03-30 |
Altius Institute For Biomedical Sciences |
NUCLEIC ACID BINDING DOMAINS AND METHODS OF USE THEREOF
|
|
US20210324398A1
(en)
|
2018-06-29 |
2021-10-21 |
Pioneer Hi-Bred International, Inc. |
Edited nac genes in plants
|
|
CA3105331A1
(en)
|
2018-07-09 |
2020-01-16 |
Cellectis |
Canola with high oleic acid
|
|
EP3831946A4
(en)
|
2018-07-31 |
2022-08-10 |
The University of Tokyo |
METHOD OF MEASUREMENT OF MEMBRANE PROTEIN ACTIVITY
|
|
WO2020028617A1
(en)
|
2018-08-01 |
2020-02-06 |
University Of Georgia Research Foundation, Inc. |
Compositions and methods for improving embryo development
|
|
GB201812603D0
(en)
|
2018-08-02 |
2018-09-19 |
British American Tobacco Investments Ltd |
Method
|
|
EP3833758A4
(en)
|
2018-08-07 |
2022-05-18 |
Modalis Therapeutics Corporation |
NOVEL TRANSCRIPTION ACTIVATOR
|
|
EP3607819A1
(en)
|
2018-08-10 |
2020-02-12 |
Vilmorin et Cie |
Resistance to xanthomonas campestris pv. campestris (xcc) in cauliflower
|
|
US10532324B1
(en)
|
2018-08-14 |
2020-01-14 |
Inscripta, Inc. |
Instruments, modules, and methods for improved detection of edited sequences in live cells
|
|
US11142740B2
(en)
|
2018-08-14 |
2021-10-12 |
Inscripta, Inc. |
Detection of nuclease edited sequences in automated modules and instruments
|
|
IL292273B2
(en)
|
2018-08-14 |
2023-10-01 |
Inscripta Inc |
Devices, modules and methods for improved detection of edited sequences in living cells
|
|
WO2020041380A1
(en)
|
2018-08-20 |
2020-02-27 |
The Broad Institute, Inc. |
Methods and compositions for optochemical control of crispr-cas9
|
|
US11834686B2
(en)
|
2018-08-23 |
2023-12-05 |
Sangamo Therapeutics, Inc. |
Engineered target specific base editors
|
|
CA3108922A1
(en)
|
2018-08-29 |
2020-03-05 |
Amyris, Inc. |
Cells and methods for selection based assay
|
|
BR112021003469A2
(pt)
|
2018-08-30 |
2021-05-18 |
The University Of North Carolina At Chapel Hill |
genes sintéticos de feedback ativado, cassetes de seed match alvo e seus usos
|
|
WO2020081149A2
(en)
|
2018-08-30 |
2020-04-23 |
Inscripta, Inc. |
Improved detection of nuclease edited sequences in automated modules and instruments
|
|
CN109706155B
(zh)
*
|
2018-08-30 |
2022-04-19 |
南京农业大学 |
pOsHEN1::OsSPL14基因表达盒及其构建方法和应用
|
|
AU2019328326A1
(en)
|
2018-08-31 |
2021-03-18 |
Yale University |
Compositions and methods for enhancing triplex and nuclease-based gene editing
|
|
SG11202101975RA
(en)
|
2018-08-31 |
2021-03-30 |
Univ Yale |
Compositions and methods for enhancing donor oligonucleotide-based gene editing
|
|
EP3623379A1
(en)
|
2018-09-11 |
2020-03-18 |
KWS SAAT SE & Co. KGaA |
Beet necrotic yellow vein virus (bnyvv)-resistance modifying gene
|
|
EP3849565A4
(en)
|
2018-09-12 |
2022-12-28 |
Fred Hutchinson Cancer Research Center |
REDUCTION OF CD33 EXPRESSION TO SELECTIVELY PROTECT THERAPEUTIC CELLS
|
|
JP2022500052A
(ja)
|
2018-09-18 |
2022-01-04 |
サンガモ セラピューティクス, インコーポレイテッド |
プログラム細胞死1(pd1)特異的ヌクレアーゼ
|
|
JP7344300B2
(ja)
|
2018-09-18 |
2023-09-13 |
ブイエヌブイ ニューコ インク. |
Arcベースのカプシドおよびその使用
|
|
KR20210060561A
(ko)
*
|
2018-09-20 |
2021-05-26 |
사노피 |
인트론-기반 범용 클로닝 방법 및 조성물
|
|
IL281615B1
(en)
|
2018-09-21 |
2025-09-01 |
Acuitas Therapeutics Inc |
Systems and methods for producing lipid nanoparticles and liposomes
|
|
GB201815672D0
(en)
|
2018-09-26 |
2018-11-07 |
Innes John Centre |
Methods for altering starch granule size profile
|
|
WO2020071528A1
(ja)
|
2018-10-04 |
2020-04-09 |
株式会社カネカ |
植物のゲノム編集に用いられるdna構築物
|
|
WO2020077236A1
(en)
|
2018-10-12 |
2020-04-16 |
The Broad Institute, Inc. |
Method for extracting nuclei or whole cells from formalin-fixed paraffin-embedded tissues
|
|
WO2020079033A1
(en)
|
2018-10-15 |
2020-04-23 |
Fondazione Telethon |
Genome editing methods and constructs
|
|
BR112021007306A2
(pt)
|
2018-10-16 |
2021-07-27 |
Pioneer Hi-Bred International, Inc. |
mapeamento fino por edição genômica e identificação de gene causal
|
|
WO2020081730A2
(en)
|
2018-10-16 |
2020-04-23 |
Massachusetts Institute Of Technology |
Methods and compositions for modulating microenvironment
|
|
AU2019368215B2
(en)
|
2018-10-22 |
2023-05-18 |
Inscripta, Inc. |
Engineered enzymes
|
|
KR20210082205A
(ko)
|
2018-10-22 |
2021-07-02 |
유니버시티 오브 로체스터 |
레트로바이러스 인테그라제-Cas9 융합 단백질을 이용한 유도된 비상동 DNA 삽입에 의한 게놈 편집
|
|
US11214781B2
(en)
|
2018-10-22 |
2022-01-04 |
Inscripta, Inc. |
Engineered enzyme
|
|
WO2020092453A1
(en)
|
2018-10-29 |
2020-05-07 |
The Broad Institute, Inc. |
Nucleobase editors comprising geocas9 and uses thereof
|
|
EP3873540A4
(en)
|
2018-10-31 |
2022-07-27 |
Mayo Foundation for Medical Education and Research |
METHODS AND MATERIALS FOR THE TREATMENT OF CANCER
|
|
EP3873500A4
(en)
|
2018-10-31 |
2023-01-11 |
Mayo Foundation for Medical Education and Research |
METHODS AND MATERIALS FOR THE TREATMENT OF CANCER
|
|
GB201817971D0
(en)
|
2018-11-02 |
2018-12-19 |
British American Tobacco Investments Ltd |
Method
|
|
ES3015004T3
(en)
|
2018-11-02 |
2025-04-28 |
Annexon Inc |
Compositions and methods for treating brain injury
|
|
KR20210089712A
(ko)
|
2018-11-07 |
2021-07-16 |
크리스퍼 테라퓨틱스 아게 |
항-cd33 면역세포 암 치료법
|
|
WO2020095248A1
(en)
|
2018-11-07 |
2020-05-14 |
Crispr Therapeutics Ag |
Anti-ptk7 immune cell cancer therapy
|
|
JP7471289B2
(ja)
|
2018-11-07 |
2024-04-19 |
クリスパー セラピューティクス アクチェンゲゼルシャフト |
抗liv1免疫細胞癌療法
|
|
US12165743B2
(en)
|
2018-11-09 |
2024-12-10 |
The Broad Institute, Inc. |
Compressed sensing for screening and tissue imaging
|
|
US12402610B2
(en)
|
2018-11-09 |
2025-09-02 |
The Broad Institute, Inc. |
Methods and compositions for modulating innate lymphoid cell pathogenic effectors
|
|
GB201818715D0
(en)
|
2018-11-16 |
2019-01-02 |
British American Tobacco Investments Ltd |
Method
|
|
US12227548B2
(en)
|
2018-11-19 |
2025-02-18 |
Dana-Farber Cancer Institute, Inc. |
Use of IRE1α-XBP1 signaling pathway biomarkers for modulating immune responses
|
|
BR112021010079A2
(pt)
|
2018-11-27 |
2021-11-23 |
Khona Scient Llc |
Armações multienzimáticas bidirecionais para a biossíntese de canabinoides
|
|
WO2020112195A1
(en)
|
2018-11-30 |
2020-06-04 |
Yale University |
Compositions, technologies and methods of using plerixafor to enhance gene editing
|
|
WO2020117526A1
(en)
|
2018-12-02 |
2020-06-11 |
Fate Therapeutics, Inc. |
IMMUNOTHERAPIES USING ENHANCED iPSC DERIVED EFFECTOR CELLS
|
|
BR112021010753A2
(pt)
|
2018-12-05 |
2021-09-21 |
Vertex Pharmaceuticals Incorporated |
Sistemas de edição de genes para editar um gene regulador de transmembrana de fibrose cística (cftr)
|
|
KR20200071198A
(ko)
|
2018-12-10 |
2020-06-19 |
네오이뮨텍, 인코퍼레이티드 |
Nrf2 발현 조절 기반 T 세포 항암면역치료법
|
|
GB201820109D0
(en)
|
2018-12-11 |
2019-01-23 |
Vib Vzw |
Plants with a lignin trait and udp-glycosyltransferase mutation
|
|
US12274205B2
(en)
|
2018-12-12 |
2025-04-15 |
Monsanto Technology Llc |
Delayed harvest of short stature corn plants
|
|
US11384344B2
(en)
|
2018-12-17 |
2022-07-12 |
The Broad Institute, Inc. |
CRISPR-associated transposase systems and methods of use thereof
|
|
CN113423831B
(zh)
|
2018-12-20 |
2023-03-10 |
瑞泽恩制药公司 |
核酸酶介导的重复扩增
|
|
WO2020132659A1
(en)
|
2018-12-21 |
2020-06-25 |
Precision Biosciences, Inc. |
Genetic modification of the hydroxyacid oxidase 1 gene for treatment of primary hyperoxaluria
|
|
US11739156B2
(en)
|
2019-01-06 |
2023-08-29 |
The Broad Institute, Inc. Massachusetts Institute of Technology |
Methods and compositions for overcoming immunosuppression
|
|
AU2020205717B2
(en)
|
2019-01-11 |
2025-09-11 |
Acuitas Therapeutics, Inc. |
Lipids for lipid nanoparticle delivery of active agents
|
|
CA3145881A1
(en)
|
2019-01-15 |
2020-07-23 |
Seminis Vegetable Seeds, Inc. |
Green bean plants with improved resistance to sclerotinia sclerotiorum and genetic markers therefor
|
|
US12156877B1
(en)
|
2019-01-15 |
2024-12-03 |
The Regents Of The University Of California |
Methods of treating conditions related to a thiamine deficiency, a thiamine-dependent enzyme, or an associated cofactor
|
|
US12351837B2
(en)
|
2019-01-23 |
2025-07-08 |
The Broad Institute, Inc. |
Supernegatively charged proteins and uses thereof
|
|
GB201900940D0
(en)
|
2019-01-23 |
2019-03-13 |
British American Tobacco Investments Ltd |
Method
|
|
EP3918080A1
(en)
|
2019-01-29 |
2021-12-08 |
The University Of Warwick |
Methods for enhancing genome engineering efficiency
|
|
JP7611151B2
(ja)
|
2019-02-06 |
2025-01-09 |
ヴィルモラン・エ・シエ |
細胞質雄性不稔を司る新たな遺伝子
|
|
WO2020172343A2
(en)
|
2019-02-19 |
2020-08-27 |
Massachusetts Institute Of Technology |
Methods for treating injuries
|
|
WO2020178193A1
(en)
|
2019-03-01 |
2020-09-10 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Method of treatment of sarcoidosis
|
|
EP3935179A4
(en)
|
2019-03-07 |
2022-11-23 |
The Trustees of Columbia University in the City of New York |
Rna-guided dna integration using tn7-like transposons
|
|
EP3708651A1
(en)
|
2019-03-12 |
2020-09-16 |
KWS SAAT SE & Co. KGaA |
Improving plant regeneration
|
|
US12419915B2
(en)
|
2019-03-13 |
2025-09-23 |
The Broad Institute, Inc. |
Microglial progenitors for regeneration of functional microglia in the central nervous system and therapeutics uses thereof
|
|
EP3942042A1
(en)
|
2019-03-19 |
2022-01-26 |
The Broad Institute, Inc. |
Methods and compositions for editing nucleotide sequences
|
|
US11001831B2
(en)
|
2019-03-25 |
2021-05-11 |
Inscripta, Inc. |
Simultaneous multiplex genome editing in yeast
|
|
WO2020198174A1
(en)
|
2019-03-25 |
2020-10-01 |
Inscripta, Inc. |
Simultaneous multiplex genome editing in yeast
|
|
PH12021500032A1
(en)
|
2019-04-03 |
2022-05-02 |
Regeneron Pharma |
Methods and compositions for insertion of antibody coding sequences into a safe harbor locus
|
|
IL299249B2
(en)
|
2019-04-03 |
2024-01-01 |
Prec Biosciences Inc |
Genetically-modified immune cells comprising a microrna-adapted shrna (shrnamir)
|
|
IL286917B
(en)
|
2019-04-04 |
2022-09-01 |
Regeneron Pharma |
Methods for scarless introduction of targeted modifications into targeting vectors
|
|
CN117178959A
(zh)
|
2019-04-04 |
2023-12-08 |
瑞泽恩制药公司 |
包括人源化凝血因子12基因座的非人动物
|
|
US20220204994A1
(en)
|
2019-04-05 |
2022-06-30 |
Precision Biosciences, Inc. |
Methods of preparing populations of genetically-modified immune cells
|
|
EP3950942A4
(en)
|
2019-04-05 |
2023-01-18 |
Osaka University |
PROCEDURE FOR MAKING A KNOCK-IN CELL
|
|
EP3956349A1
(en)
|
2019-04-17 |
2022-02-23 |
The Broad Institute, Inc. |
Adenine base editors with reduced off-target effects
|
|
BR112021022411A2
(pt)
|
2019-05-13 |
2022-03-15 |
Kws Saat Se & Co Kgaa |
Tolerância à seca em milho
|
|
GB201906768D0
(en)
|
2019-05-14 |
2019-06-26 |
British American Tobacco Investments Ltd |
Method
|
|
PH12021553009A1
(en)
|
2019-05-23 |
2022-11-07 |
Univ Nanjing Agricultural |
Methods for improving rice grain yield
|
|
AR118995A1
(es)
|
2019-05-25 |
2021-11-17 |
Kws Saat Se & Co Kgaa |
Mejorador de la inducción de haploides
|
|
WO2020243371A1
(en)
|
2019-05-28 |
2020-12-03 |
Massachusetts Institute Of Technology |
Methods and compositions for modulating immune responses
|
|
AU2020284555A1
(en)
|
2019-05-28 |
2021-12-23 |
Selecta Biosciences, Inc. |
Methods and compositions for attenuated anti-viral transfer vector immune response
|
|
WO2020243661A1
(en)
|
2019-05-31 |
2020-12-03 |
The Broad Institute, Inc. |
Methods for treating metabolic disorders by targeting adcy5
|
|
AU2020286382A1
(en)
|
2019-06-04 |
2021-11-04 |
Regeneron Pharmaceuticals, Inc. |
Non-human animals comprising a humanized TTR locus with a beta-slip mutation and methods of use
|
|
WO2020244759A1
(en)
|
2019-06-05 |
2020-12-10 |
Klemm & Sohn Gmbh & Co. Kg |
New plants having a white foliage phenotype
|
|
AU2020288623A1
(en)
|
2019-06-06 |
2022-01-06 |
Inscripta, Inc. |
Curing for recursive nucleic acid-guided cell editing
|
|
MX2021015122A
(es)
|
2019-06-07 |
2022-04-06 |
Regeneron Pharma |
Animales no humanos que comprenden un locus de albumina humanizado.
|
|
JP2022536364A
(ja)
|
2019-06-13 |
2022-08-15 |
ザ ジェネラル ホスピタル コーポレイション |
操作されたヒト内在性ウイルス様粒子および細胞への送達のためのその使用方法
|
|
ES3034102T3
(en)
|
2019-06-14 |
2025-08-13 |
Regeneron Pharma |
Models of tauopathy
|
|
EP3987024A4
(en)
|
2019-06-20 |
2023-11-01 |
University Of Massachusetts |
COMPOSITIONS AND METHODS FOR ENHANCED GENOMIC EDITING
|
|
AU2020297499A1
(en)
|
2019-06-21 |
2022-02-03 |
Inscripta, Inc. |
Genome-wide rationally-designed mutations leading to enhanced lysine production in E. coli
|
|
WO2020254850A1
(en)
|
2019-06-21 |
2020-12-24 |
Vilmorin & Cie |
Improvement of quality and permanence of green color of peppers at maturity and over-maturity
|
|
US10927385B2
(en)
|
2019-06-25 |
2021-02-23 |
Inscripta, Inc. |
Increased nucleic-acid guided cell editing in yeast
|
|
MX2022000016A
(es)
|
2019-06-27 |
2022-02-24 |
Crispr Therapeutics Ag |
Uso de linfocitos t con receptor de antigeno quimerico e inhibidores de linfocitos citoliticos naturales para el tratamiento del cancer.
|
|
EP3757219A1
(en)
|
2019-06-28 |
2020-12-30 |
KWS SAAT SE & Co. KGaA |
Enhanced plant regeneration and transformation by using grf1 booster gene
|
|
GB201909562D0
(en)
|
2019-07-03 |
2019-08-14 |
British American Tobacco Investments Ltd |
Method
|
|
CN114450265B
(zh)
|
2019-07-03 |
2024-12-24 |
菲克特生物科学股份有限公司 |
阳离子脂质及其用途
|
|
GB201909563D0
(en)
|
2019-07-03 |
2019-08-14 |
British American Tobacco Investments Ltd |
Method
|
|
WO2021004938A1
(en)
|
2019-07-05 |
2021-01-14 |
Biogemma |
Method for increasing yield in plants
|
|
AU2020310877B2
(en)
|
2019-07-11 |
2024-05-23 |
Consejo Nacional De Investigaciones Científicas Y Técnicas |
Methods for improved regeneration of transgenic plants using Growth-Regulating Factor (GRF), GRF-Interacting Factor (GIF), or chimeric GRF-GIF genes and proteins
|
|
WO2021013950A1
(en)
|
2019-07-23 |
2021-01-28 |
Mnemo Therapeutics |
Immune cells defective for suv39h1
|
|
FR3099178A1
(fr)
|
2019-07-24 |
2021-01-29 |
Soltis |
Tournesol à teneur élevée en acide oléique et procédé d’obtention
|
|
EP4004216A1
(en)
|
2019-07-25 |
2022-06-01 |
Precision BioSciences, Inc. |
Compositions and methods for sequential stacking of nucleic acid sequences into a genomic locus
|
|
US10501404B1
(en)
|
2019-07-30 |
2019-12-10 |
Factor Bioscience Inc. |
Cationic lipids and transfection methods
|
|
US12344850B2
(en)
|
2019-07-30 |
2025-07-01 |
Pairwise Plants Services, Inc. |
Morphogenic regulators and methods of using the same
|
|
WO2021019272A1
(en)
|
2019-07-31 |
2021-02-04 |
Vilmorin & Cie |
Tolerance to tolcndv in cucumber
|
|
EP3772542A1
(en)
|
2019-08-07 |
2021-02-10 |
KWS SAAT SE & Co. KGaA |
Modifying genetic variation in crops by modulating the pachytene checkpoint protein 2
|
|
JP2022544825A
(ja)
|
2019-08-20 |
2022-10-21 |
プレシジョン バイオサイエンシズ,インク. |
細胞免疫療法のためのリンパ球枯渇投与レジメン
|
|
WO2021035170A1
(en)
|
2019-08-21 |
2021-02-25 |
Precision Biosciences, Inc. |
Compositions and methods for tcr reprogramming using fusion proteins
|
|
US20220298501A1
(en)
|
2019-08-30 |
2022-09-22 |
The Broad Institute, Inc. |
Crispr-associated mu transposase systems
|
|
KR20220101073A
(ko)
|
2019-08-30 |
2022-07-19 |
예일 유니버시티 |
핵산을 세포로 전달하기 위한 조성물 및 방법
|
|
BR112022003891A2
(pt)
|
2019-09-06 |
2022-05-31 |
Crispr Therapeutics Ag |
Células t geneticamente manipuladas possuindo persistência melhorada em cultura
|
|
AU2020355000A1
(en)
|
2019-09-23 |
2022-03-17 |
Omega Therapeutics, Inc. |
Compositions and methods for modulating apolipoprotein B (APOB) gene expression
|
|
JP2022548399A
(ja)
|
2019-09-23 |
2022-11-18 |
オメガ セラピューティクス, インコーポレイテッド |
肝細胞核因子4-アルファ(HNF4α)遺伝子発現をモジュレートするための組成物および方法
|
|
SG10202008262UA
(en)
|
2019-09-26 |
2021-04-29 |
Seminis Vegetable Seeds Inc |
Lettuce plants having resistance to nasonovia ribisnigri biotype nr:1
|
|
GB201914137D0
(en)
|
2019-10-01 |
2019-11-13 |
Univ Leeds Innovations Ltd |
Modified Plants
|
|
US11981922B2
(en)
|
2019-10-03 |
2024-05-14 |
Dana-Farber Cancer Institute, Inc. |
Methods and compositions for the modulation of cell interactions and signaling in the tumor microenvironment
|
|
US12435330B2
(en)
|
2019-10-10 |
2025-10-07 |
The Broad Institute, Inc. |
Methods and compositions for prime editing RNA
|
|
WO2021074367A1
(en)
|
2019-10-17 |
2021-04-22 |
KWS SAAT SE & Co. KGaA |
Enhanced disease resistance of crops by downregulation of repressor genes
|
|
EP3808170A1
(en)
|
2019-10-17 |
2021-04-21 |
Bejo Zaden B.V. |
Lactuca sativa resistance to bremia lactucae
|
|
US20220411479A1
(en)
|
2019-10-30 |
2022-12-29 |
Precision Biosciences, Inc. |
Cd20 chimeric antigen receptors and methods of use for immunotherapy
|
|
CN112779266A
(zh)
|
2019-11-06 |
2021-05-11 |
青岛清原化合物有限公司 |
在生物体内创制新基因的方法及应用
|
|
IL292605B2
(en)
|
2019-11-08 |
2025-09-01 |
Regeneron Pharma |
CRISPR and AAV strategies for treating childhood X-linked retinoschisis
|
|
JP7753203B2
(ja)
|
2019-11-12 |
2025-10-14 |
カー・ヴェー・エス ザート エス・エー ウント コー. カー・ゲー・アー・アー |
ヘテロデラ属の病原体に対する耐性遺伝子
|
|
EP4057802A1
(en)
|
2019-11-14 |
2022-09-21 |
Vilmorin & Cie |
Resistance to acidovorax valerianellae in corn salad
|
|
WO2021095847A1
(ja)
|
2019-11-14 |
2021-05-20 |
国立大学法人広島大学 |
抗原特異的受容体遺伝子を環状dnaを用いてt細胞ゲノムに導入する方法
|
|
JP7448120B2
(ja)
|
2019-11-14 |
2024-03-12 |
国立研究開発法人農業・食品産業技術総合研究機構 |
プラズマを用いてゲノム編集酵素を植物細胞内に導入する方法
|
|
WO2021102059A1
(en)
|
2019-11-19 |
2021-05-27 |
Inscripta, Inc. |
Methods for increasing observed editing in bacteria
|
|
WO2021108363A1
(en)
|
2019-11-25 |
2021-06-03 |
Regeneron Pharmaceuticals, Inc. |
Crispr/cas-mediated upregulation of humanized ttr allele
|
|
AU2020391435A1
(en)
|
2019-11-27 |
2022-06-23 |
Cibus Europe B.V. |
Tal-effector nucleases for gene editing
|
|
US20230036065A1
(en)
|
2019-12-06 |
2023-02-02 |
Precision Biosciences, Inc. |
Methods for cancer immunotherapy
|
|
AU2020402526B2
(en)
|
2019-12-10 |
2025-01-23 |
Inscripta, Inc. |
Novel MAD nucleases
|
|
US10704033B1
(en)
|
2019-12-13 |
2020-07-07 |
Inscripta, Inc. |
Nucleic acid-guided nucleases
|
|
EP4074821A4
(en)
|
2019-12-13 |
2024-01-17 |
Chugai Seiyaku Kabushiki Kaisha |
SYSTEM FOR DETECTION OF EXTRACELLULAR PURINERGICAL RECEPTOR LIGAND AND NON-HUMAN ANIMAL TO WHICH THE LATTER WAS TRANSFERRED
|
|
EP3835309A1
(en)
|
2019-12-13 |
2021-06-16 |
KWS SAAT SE & Co. KGaA |
Method for increasing cold or frost tolerance in a plant
|
|
CN113061626B
(zh)
*
|
2019-12-16 |
2024-01-19 |
中国科学院脑科学与智能技术卓越创新中心 |
一种组织特异性敲除斑马鱼基因的方法及应用
|
|
IL292895A
(en)
|
2019-12-18 |
2022-07-01 |
Inscripta Inc |
Cascade/dcas3 complementation assays for in vivo detection of nucleic acid-guided nuclease edited cells
|
|
GB201918902D0
(en)
|
2019-12-19 |
2020-02-05 |
Genome Res Ltd |
Cell differentiation
|
|
US10689669B1
(en)
|
2020-01-11 |
2020-06-23 |
Inscripta, Inc. |
Automated multi-module cell processing methods, instruments, and systems
|
|
US12165747B2
(en)
|
2020-01-23 |
2024-12-10 |
The Broad Institute, Inc. |
Molecular spatial mapping of metastatic tumor microenvironment
|
|
AU2021213705A1
(en)
|
2020-01-27 |
2022-06-16 |
Inscripta, Inc. |
Electroporation modules and instrumentation
|
|
BR112022014799A2
(pt)
|
2020-01-31 |
2022-09-20 |
Calyxt Inc |
Planta de soja, parte de planta ou célula de planta, método para gerar uma planta de soja e composição de óleo de soja
|
|
EP4100525A1
(en)
|
2020-02-05 |
2022-12-14 |
Institut National de la Santé et de la Recherche Médicale (INSERM) |
Methods of treatment of cancer disease by targeting an epigenetic factor
|
|
WO2021158915A1
(en)
|
2020-02-06 |
2021-08-12 |
Precision Biosciences, Inc. |
Recombinant adeno-associated virus compositions and methods for producing and using the same
|
|
US20230091338A1
(en)
|
2020-02-24 |
2023-03-23 |
Pioneer Hi-Bred International, Inc. |
Intra-genomic homologous recombination
|
|
BR112022017197A2
(pt)
|
2020-02-28 |
2022-11-01 |
Pioneer Hi Bred Int |
Sistema de produção haploide duplicado de sorgo
|
|
CA3169128A1
(en)
|
2020-02-28 |
2021-09-02 |
Ling MENG |
Immature inflorescence meristem editing
|
|
CN115485385A
(zh)
|
2020-03-04 |
2022-12-16 |
瑞泽恩制药公司 |
用于使肿瘤细胞对免疫疗法敏感的方法和组合物
|
|
WO2021183636A1
(en)
|
2020-03-10 |
2021-09-16 |
Calyxt, Inc. |
Transformation and regeneration of cannabaceae
|
|
WO2021183720A1
(en)
|
2020-03-11 |
2021-09-16 |
Omega Therapeutics, Inc. |
Compositions and methods for modulating forkhead box p3 (foxp3) gene expression
|
|
EP4129050A4
(en)
|
2020-03-26 |
2024-05-08 |
National Agriculture And Food Research Organization |
METHOD FOR PRODUCING A TEMPERATURE SENSITIVE MALE STERILE PLANT
|
|
CA3172449A1
(en)
|
2020-03-27 |
2021-09-30 |
Erik Hans MANTING |
Ex vivo use of modified cells of leukemic origin for enhancing the efficacy of adoptive cell therapy
|
|
CN115697044A
(zh)
|
2020-03-31 |
2023-02-03 |
艾洛生物系统有限公司 |
西瓜和其他葫芦科中内源罗汉果苷途径基因的调控
|
|
WO2021202648A1
(en)
|
2020-03-31 |
2021-10-07 |
Calyxt, Inc. |
Agrobacterium-mediated infiltration of cannabaceae
|
|
JP2023521055A
(ja)
|
2020-04-09 |
2023-05-23 |
アール・ジエイ・レイノルズ・タバコ・カンパニー |
ニコチアナ・タバカムにおけるニコチンレベルの調整方法
|
|
EP4135511A1
(en)
|
2020-04-14 |
2023-02-22 |
Academisch Ziekenhuis Leiden (h.o.d.n. LUMC) |
Methods for induction of endogenous tandem duplication events
|
|
NL2025344B1
(en)
|
2020-04-14 |
2021-10-26 |
Academisch Ziekenhuis Leiden |
Methods for induction of endogenous tandem duplication events
|
|
US20210332388A1
(en)
|
2020-04-24 |
2021-10-28 |
Inscripta, Inc. |
Compositions, methods, modules and instruments for automated nucleic acid-guided nuclease editing in mammalian cells
|
|
WO2021224416A1
(en)
|
2020-05-06 |
2021-11-11 |
Cellectis S.A. |
Methods to genetically modify cells for delivery of therapeutic proteins
|
|
EP4146797A1
(en)
|
2020-05-06 |
2023-03-15 |
Orchard Therapeutics (Europe) Limited |
Treatment for neurodegenerative diseases
|
|
EP4146812A1
(en)
|
2020-05-06 |
2023-03-15 |
Cellectis S.A. |
Methods for targeted insertion of exogenous sequences in cellular genomes
|
|
WO2021226558A1
(en)
|
2020-05-08 |
2021-11-11 |
The Broad Institute, Inc. |
Methods and compositions for simultaneous editing of both strands of a target double-stranded nucleotide sequence
|
|
US20230183664A1
(en)
|
2020-05-11 |
2023-06-15 |
Precision Biosciences, Inc. |
Self-limiting viral vectors encoding nucleases
|
|
US11787841B2
(en)
|
2020-05-19 |
2023-10-17 |
Inscripta, Inc. |
Rationally-designed mutations to the thrA gene for enhanced lysine production in E. coli
|
|
BR112022023443A2
(pt)
|
2020-05-29 |
2022-12-20 |
Kws Saat Se & Co Kgaa |
Indução de haploides em plantas
|
|
WO2021245435A1
(en)
|
2020-06-03 |
2021-12-09 |
Vilmorin & Cie |
Melon plants resistant to scab disease, aphids and powdery mildew
|
|
JP2023530234A
(ja)
|
2020-06-05 |
2023-07-14 |
ザ・ブロード・インスティテュート・インコーポレイテッド |
新生物を治療するための組成物および方法
|
|
IL298618A
(en)
|
2020-06-05 |
2023-01-01 |
Vilmorin & Cie |
Tobrfv resistance of Solanum lycopersicum plants
|
|
AU2021292695A1
(en)
|
2020-06-19 |
2023-02-02 |
Fate Therapeutics, Inc. |
Combining iPSC-derived effector cell types for immunotherapy use
|
|
WO2021260139A1
(en)
|
2020-06-25 |
2021-12-30 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods of treatment and diagnostic of pathological conditions associated with intense stress
|
|
CN116133679A
(zh)
|
2020-06-30 |
2023-05-16 |
门德斯有限公司 |
白血病衍生细胞在卵巢癌疫苗中的用途
|
|
EP4181664A1
(en)
|
2020-07-14 |
2023-05-24 |
KWS SAAT SE & Co. KGaA |
Methods for identifying and selecting maize plants with resistance to northern corn leaf blight
|
|
AU2021204717A1
(en)
|
2020-07-15 |
2022-02-03 |
Seminis Vegetable Seeds, Inc. |
Green Bean Plants with Improved Disease Resistance
|
|
CA3189338A1
(en)
|
2020-07-16 |
2022-01-20 |
Acuitas Therapeutics, Inc. |
Cationic lipids for use in lipid nanoparticles
|
|
WO2022020800A2
(en)
|
2020-07-24 |
2022-01-27 |
The General Hospital Corporation |
Enhanced virus-like particles and methods of use thereof for delivery to cells
|
|
EP4188395A1
(en)
|
2020-07-30 |
2023-06-07 |
Institut Curie |
Immune cells defective for socs1
|
|
EP4192875A1
(en)
|
2020-08-10 |
2023-06-14 |
Precision BioSciences, Inc. |
Antibodies and fragments specific for b-cell maturation antigen and uses thereof
|
|
EP4501951A3
(en)
|
2020-08-25 |
2025-04-30 |
Kite Pharma, Inc. |
T cells with improved functionality
|
|
JP2023544970A
(ja)
|
2020-08-31 |
2023-10-26 |
イエール ユニバーシティ |
細胞への核酸の送達のための組成物及び方法
|
|
CA3194019A1
(en)
|
2020-09-04 |
2022-03-10 |
National University Corporation Kobe University |
Miniaturized cytidine deaminase-containing complex for modifying double-stranded dna
|
|
US20230340149A1
(en)
|
2020-09-07 |
2023-10-26 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods of treatment of inflammatory bowel diseases
|
|
EP4214314A4
(en)
|
2020-09-15 |
2024-10-16 |
Inscripta, Inc. |
Crispr editing to embed nucleic acid landing pads into genomes of live cells
|
|
EP3971295A1
(en)
|
2020-09-16 |
2022-03-23 |
FRAUNHOFER-GESELLSCHAFT zur Förderung der angewandten Forschung e.V. |
Methods for the production of genome edited plants
|
|
KR20230074515A
(ko)
|
2020-09-23 |
2023-05-30 |
크리스퍼 테라퓨틱스 아게 |
개선된 기능성 및 지속성을 갖는 붕괴된 레그나제-1 및/또는 tgfbrii를 지니는 유전자 조작된 t 세포
|
|
JP2023543803A
(ja)
|
2020-09-24 |
2023-10-18 |
ザ ブロード インスティテュート,インコーポレーテッド |
プライム編集ガイドrna、その組成物、及びその使用方法
|
|
IL301846A
(en)
|
2020-10-02 |
2023-06-01 |
Vilmorin & Cie |
A hotel with an extended shelf life
|
|
US20230365995A1
(en)
|
2020-10-07 |
2023-11-16 |
Precision Biosciences, Inc. |
Lipid nanoparticle compositions
|
|
CR20230175A
(es)
|
2020-10-23 |
2023-07-26 |
Elo Life Systems Inc |
Métodos para producir plantas de vainilla con mejor sabor y producción agronómica
|
|
CN116406383A
(zh)
|
2020-11-06 |
2023-07-07 |
日商基因编辑力股份有限公司 |
FokI核酸酶结构域的突变体
|
|
EP4240874A1
(en)
|
2020-11-06 |
2023-09-13 |
Institut National de la Santé et de la Recherche Médicale (INSERM) |
Methods for diagnosis and treating polycystic ovary syndrome (pcos)
|
|
US11512297B2
(en)
|
2020-11-09 |
2022-11-29 |
Inscripta, Inc. |
Affinity tag for recombination protein recruitment
|
|
WO2022103799A1
(en)
|
2020-11-10 |
2022-05-19 |
Industrial Microbes, Inc. |
Microorganisms capable of producing poly(hiba) from feedstock
|
|
WO2022103785A1
(en)
|
2020-11-10 |
2022-05-19 |
Mayo Foundation For Medical Education And Research |
Methods and materials for treating heart failure
|
|
WO2022109316A1
(en)
|
2020-11-20 |
2022-05-27 |
Revivicor, Inc. |
Multi-transgenic pigs with growth hormone receptor knockout for xenotransplantation
|
|
EP4251282A1
(en)
|
2020-11-27 |
2023-10-04 |
Institut National de la Santé et de la Recherche Médicale (INSERM) |
Methods for diagnosis and monitoring of toxic epidermal necrolysis
|
|
US20230416786A1
(en)
|
2020-11-30 |
2023-12-28 |
Cellectis Sa |
Use of aminoquinoline compounds for higher gene integration
|
|
US11661459B2
(en)
|
2020-12-03 |
2023-05-30 |
Century Therapeutics, Inc. |
Artificial cell death polypeptide for chimeric antigen receptor and uses thereof
|
|
CA3201621A1
(en)
|
2020-12-03 |
2022-06-09 |
Century Therapeutics, Inc. |
Genetically engineered cells and uses thereof
|
|
EP4255172A1
(en)
|
2020-12-03 |
2023-10-11 |
Vilmorin & Cie |
Tomato plants resistant to tobrfv, tmv, tomv and tommv and corresponding resistance genes
|
|
EP4019639A1
(en)
|
2020-12-22 |
2022-06-29 |
KWS SAAT SE & Co. KGaA |
Promoting regeneration and transformation in beta vulgaris
|
|
EP4019638A1
(en)
|
2020-12-22 |
2022-06-29 |
KWS SAAT SE & Co. KGaA |
Promoting regeneration and transformation in beta vulgaris
|
|
US20220193134A1
(en)
|
2020-12-23 |
2022-06-23 |
Crispr Therapeutics Ag |
Co-use of lenalidomide with car-t cells
|
|
US20240316090A1
(en)
|
2020-12-28 |
2024-09-26 |
Arcturus Therapeutics, Inc. |
Transcription activator-like effector nucleases (talens) targeting hbv
|
|
CA3204158A1
(en)
|
2021-01-04 |
2022-07-07 |
Juhan Kim |
Mad nucleases
|
|
US20240376451A1
(en)
|
2021-01-07 |
2024-11-14 |
Inscripta, Inc. |
Mad nucleases
|
|
WO2022150790A2
(en)
|
2021-01-11 |
2022-07-14 |
The Broad Institute, Inc. |
Prime editor variants, constructs, and methods for enhancing prime editing efficiency and precision
|
|
US20240318159A1
(en)
|
2021-01-12 |
2024-09-26 |
Mitolab Inc. |
Context-dependent, double-stranded dna-specific deaminases and uses thereof
|
|
CN116981697A
(zh)
|
2021-01-14 |
2023-10-31 |
森迪生物科学公司 |
可分泌有效载荷调节
|
|
CA3203705A1
(en)
|
2021-01-22 |
2022-07-28 |
Erik Hans MANTING |
Methods of tumor vaccination
|
|
US20250127811A1
(en)
|
2021-01-28 |
2025-04-24 |
Precision Biosciences, Inc. |
Modulation of tgf beta signaling in genetically-modified eukaryotic cells
|
|
US11884924B2
(en)
|
2021-02-16 |
2024-01-30 |
Inscripta, Inc. |
Dual strand nucleic acid-guided nickase editing
|
|
EP4305153A1
(en)
|
2021-03-09 |
2024-01-17 |
CRISPR Therapeutics AG |
Genetically engineered t cells with ptpn2 knockout have improved functionality and anti-tumor activity
|
|
WO2022190058A1
(en)
|
2021-03-12 |
2022-09-15 |
Dcprime B.V. |
Methods of vaccination and use of cd47 blockade
|
|
WO2022198093A1
(en)
|
2021-03-18 |
2022-09-22 |
Calyxt, Inc. |
Producing albumin using plant cell matrices
|
|
WO2022198107A1
(en)
|
2021-03-18 |
2022-09-22 |
Calyxt, Inc. |
Producing betalain in cannabaceae plant parts
|
|
WO2022198094A1
(en)
|
2021-03-18 |
2022-09-22 |
Calyxt, Inc. |
Producing albumin in cannabaceae plant parts
|
|
WO2022198106A1
(en)
|
2021-03-18 |
2022-09-22 |
Calyxt, Inc. |
Producing betalains using plant cell matrices
|
|
US20240191245A1
(en)
|
2021-03-18 |
2024-06-13 |
Calyxt, Inc. |
Plant cell matrices and methods thereof
|
|
WO2022208489A1
(en)
|
2021-04-02 |
2022-10-06 |
Vilmorin & Cie |
Semi-determinate or determinate growth habit trait in cucurbita
|
|
US20220333074A1
(en)
|
2021-04-07 |
2022-10-20 |
Century Therapeutics, Inc. |
Compositions and Methods for Generating Alpha-Beta T Cells from Induced Pluripotent Stem Cells
|
|
CA3214661A1
(en)
|
2021-04-07 |
2022-10-13 |
Century Therapeutics, Inc. |
Combined artificial cell death/reporter system polypeptide for chimeric antigen receptor cell and uses thereof
|
|
WO2022216514A1
(en)
|
2021-04-07 |
2022-10-13 |
Century Therapeutics, Inc. |
Compositions and methods for generating gamma-delta t cells from induced pluripotent stem cells
|
|
WO2022218998A1
(en)
|
2021-04-13 |
2022-10-20 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for treating hepatitis b and d virus infection
|
|
US20240141311A1
(en)
|
2021-04-22 |
2024-05-02 |
North Carolina State University |
Compositions and methods for generating male sterile plants
|
|
AU2022261125A1
(en)
|
2021-04-23 |
2023-11-23 |
University Of Rochester |
Genome editing by directed non-homologous dna insertion using a retroviral integrase-cas fusion protein and methods of treatment
|
|
US20240197880A1
(en)
|
2021-04-30 |
2024-06-20 |
Cellectis S.A. |
New anti-muc1 cars and gene edited immune cells for solid tumors cancer immunotherapy
|
|
EP4337769A1
(en)
|
2021-05-10 |
2024-03-20 |
SQZ Biotechnologies Company |
Methods for delivering genome editing molecules to the nucleus or cytosol of a cell and uses thereof
|
|
WO2022251644A1
(en)
|
2021-05-28 |
2022-12-01 |
Lyell Immunopharma, Inc. |
Nr4a3-deficient immune cells and uses thereof
|
|
US20230052243A1
(en)
|
2021-06-02 |
2023-02-16 |
Lyell Immunopharma, Inc. |
Nr4a-deficient cells expressing c-jun and uses thereof
|
|
WO2022271548A2
(en)
|
2021-06-23 |
2022-12-29 |
Massachusetts Institute Of Technology |
Compositions, methods and systems for the delivery of gene editing material to cells
|
|
JP2024523759A
(ja)
|
2021-07-07 |
2024-06-28 |
サイバス オイローペ ベスローテン ヴェンノーツハップ |
インテインと融合した転写活性化因子様エフェクター
|
|
WO2023283359A2
(en)
|
2021-07-07 |
2023-01-12 |
Omega Therapeutics, Inc. |
Compositions and methods for modulating secreted frizzled receptor protein 1 (sfrp1) gene expression
|
|
CA3221517A1
(en)
|
2021-07-30 |
2023-02-02 |
Monika KLOIBER-MAITZ |
Plants with improved digestibility and marker haplotypes
|
|
MX2024001624A
(es)
|
2021-08-06 |
2024-04-30 |
Vilmorin & Cie |
Resistencia a leveillula taurica en el pimiento.
|
|
JP7125727B1
(ja)
|
2021-09-07 |
2022-08-25 |
国立大学法人千葉大学 |
核酸配列改変用組成物および核酸配列の標的部位を改変する方法
|
|
US20230128917A1
(en)
|
2021-09-14 |
2023-04-27 |
Crispr Therapeutics Ag |
Genetically engineered immune cells having a disrupted cd83 gene
|
|
CN118284700A
(zh)
|
2021-09-17 |
2024-07-02 |
希博斯欧洲有限公司 |
转化大麻科细胞
|
|
EP4404740A1
(en)
|
2021-09-20 |
2024-07-31 |
Revivicor Inc. |
Multitransgenic pigs comprising ten genetic modifications for xenotransplantation
|
|
CN118284701A
(zh)
|
2021-09-27 |
2024-07-02 |
孟山都技术公司 |
用于转化从单子叶植物种子切除的胚外植体的组合物和方法
|
|
GB202113933D0
(en)
|
2021-09-29 |
2021-11-10 |
Genome Res Ltd |
Methods for gene editing
|
|
US20230141563A1
(en)
|
2021-10-12 |
2023-05-11 |
Selecta Biosciences, Inc. |
Methods and compositions for attenuating anti-viral transfer vector igm responses
|
|
IL311962A
(en)
|
2021-10-14 |
2024-06-01 |
Lonza Sales Ag |
Modified producer cells for extracellular vesicle production
|
|
EP4416292A2
(en)
|
2021-10-14 |
2024-08-21 |
Arsenal Biosciences, Inc. |
Immune cells having co-expressed shrnas and logic gate systems
|
|
WO2023064872A1
(en)
|
2021-10-14 |
2023-04-20 |
Precision Biosciences, Inc. |
Combinations of anti-bcma car t cells and gamma secretase inhibitors
|
|
WO2023070003A1
(en)
|
2021-10-19 |
2023-04-27 |
Precision Biosciences, Inc. |
Gene editing methods for treating alpha-1 antitrypsin (aat) deficiency
|
|
US20230133695A1
(en)
|
2021-10-20 |
2023-05-04 |
University Of Rochester |
Methods and compositions for rejuvenating cns glial populations by suppresion of transcription factors
|
|
CA3234404A1
(en)
|
2021-10-20 |
2023-04-27 |
Steven A. Goldman |
Treatment with genetically modified cells, and genetically modified cells per se, with increased competitive advantage and/or decreased competitive disadvantage
|
|
WO2023070043A1
(en)
|
2021-10-20 |
2023-04-27 |
Yale University |
Compositions and methods for targeted editing and evolution of repetitive genetic elements
|
|
JP2024540987A
(ja)
|
2021-10-21 |
2024-11-06 |
バーテックス ファーマシューティカルズ インコーポレイテッド |
低免疫細胞
|
|
JP2024540411A
(ja)
|
2021-11-08 |
2024-10-31 |
プロジェントス・セラピューティクス・インコーポレイテッド |
血小板由来成長因子受容体(pdgfr)アルファ阻害剤及びその使用
|
|
EP4430206A1
(en)
|
2021-11-10 |
2024-09-18 |
Encodia, Inc. |
Methods for barcoding macromolecules in individual cells
|
|
WO2023091910A1
(en)
|
2021-11-16 |
2023-05-25 |
Precision Biosciences, Inc. |
Methods for cancer immunotherapy
|
|
CA3238700A1
(en)
|
2021-11-23 |
2022-11-23 |
Philippe Duchateau |
New tale protein scaffolds with improved on-target/off-target activity ratios
|
|
WO2023093862A1
(en)
|
2021-11-26 |
2023-06-01 |
Epigenic Therapeutics Inc. |
Method of modulating pcsk9 and uses thereof
|
|
US20250027097A1
(en)
|
2021-11-30 |
2025-01-23 |
Pioneer Hi-Bred International, Inc. |
High efficiency large scale chromosomal genome manipulation
|
|
GB202117314D0
(en)
|
2021-11-30 |
2022-01-12 |
Clarke David John |
Cyclic nucleic acid fragmentation
|
|
JP2024544013A
(ja)
|
2021-12-03 |
2024-11-26 |
ザ ブロード インスティテュート,インコーポレーテッド |
有効なin vivo送達のための組成物および方法
|
|
US20250382334A1
(en)
|
2021-12-03 |
2025-12-18 |
The Broad Institute, Inc. |
Self-assembling virus-like particles for delivery of nucleic acid programmable fusion proteins and methods of making and using same
|
|
US20230193310A1
(en)
|
2021-12-10 |
2023-06-22 |
Seminis Vegetabe Seeds, Inc. |
Lettuce plants having resistance to downy mildew
|
|
GB202118058D0
(en)
|
2021-12-14 |
2022-01-26 |
Univ Warwick |
Methods to increase yields in crops
|
|
EP4450634A4
(en)
|
2021-12-15 |
2025-12-24 |
Nanjing Genscript Biotech Co Ltd |
INTEGRATION SITE DETECTION METHOD
|
|
WO2023111913A1
(en)
|
2021-12-15 |
2023-06-22 |
Crispr Therapeutics Ag |
Engineered anti-liv1 cell with regnase-1 and/or tgfbrii disruption
|
|
WO2023114943A2
(en)
|
2021-12-16 |
2023-06-22 |
Acuitas Therapeutics, Inc. |
Lipids for use in lipid nanoparticle formulations
|
|
US20250087303A1
(en)
*
|
2021-12-17 |
2025-03-13 |
Altius Institute For Biomedical Sciences |
Nucleic Acid Sequences Encoding Repeated Sequences Resistant to Recombination in Viruses
|
|
WO2023119201A2
(en)
|
2021-12-22 |
2023-06-29 |
Crispr Therapeutics Ag |
Genetically engineered t cells with disrupted casitas b-lineage lymphoma proto-oncogene-b (cblb) and uses thereof
|
|
EP4456910A1
(en)
|
2021-12-28 |
2024-11-06 |
Mnemo Therapeutics |
Immune cells with inactivated suv39h1 and modified tcr
|
|
CA3243966A1
(en)
|
2021-12-29 |
2023-07-06 |
Century Therapeutics, Inc. |
Genetically modified cells with anti-CD19/anti-CD22 chimeric antigenic receptors, and their uses
|
|
EP4457342A1
(en)
|
2021-12-29 |
2024-11-06 |
Bristol-Myers Squibb Company |
Generation of landing pad cell lines
|
|
EP4472648A1
(en)
|
2022-02-01 |
2024-12-11 |
University of Rochester |
Methods of generating a population of neurons from human glial progenitor cells and genetic constructs for carrying out such methods
|
|
JP2025505600A
(ja)
|
2022-02-03 |
2025-02-28 |
ニコベンチャーズ トレーディング リミテッド |
タバコ植物のアルカロイド含有量を調節する方法
|
|
WO2023148476A1
(en)
|
2022-02-03 |
2023-08-10 |
Nicoventures Trading Limited |
Method of modulating alkaloid content in tobacco plants
|
|
JP2025505606A
(ja)
|
2022-02-04 |
2025-02-28 |
ニコベンチャーズ トレーディング リミテッド |
タバコ植物のアルカロイド含有量を調節する方法
|
|
US20250161413A1
(en)
|
2022-02-16 |
2025-05-22 |
Dana-Farber Cancer Institute, Inc. |
Methods for decreasing pathologic alpha-synuclein using agents that modulate fndc5 or biologically active fragments thereof
|
|
EP4486890A1
(en)
|
2022-03-01 |
2025-01-08 |
CRISPR Therapeutics AG |
Methods and compositions for treating angiopoietin-like 3 (angptl3) related conditions
|
|
US20230357437A1
(en)
|
2022-03-09 |
2023-11-09 |
Selecta Biosciences, Inc. |
Immunosuppressants in combination with anti-igm agents and related dosing
|
|
AU2023240501A1
(en)
|
2022-03-21 |
2024-10-31 |
Crispr Therapeutics Ag |
Methods and compositions for treating lipoprotein-related diseases
|
|
US20230303713A1
(en)
|
2022-03-23 |
2023-09-28 |
Crispr Therapeutics Ag |
Anti-cd19 car-t cells with multiple gene edits and therapeutic uses thereof
|
|
TW202346575A
(zh)
|
2022-03-23 |
2023-12-01 |
瑞士商Crispr治療公司 |
具有regnase-1及/或tgfbrii破壞的抗cd83 car-t細胞
|
|
EP4256950A1
(en)
|
2022-04-06 |
2023-10-11 |
Vilmorin et Cie |
Tolerance to cgmmv in cucumber
|
|
GB202205148D0
(en)
|
2022-04-07 |
2022-05-25 |
Nicoventures Trading Ltd |
Method
|
|
GB202205149D0
(en)
|
2022-04-07 |
2022-05-25 |
Nicoventures Trading Ltd |
Method
|
|
US20250222029A1
(en)
|
2022-04-08 |
2025-07-10 |
Fate Therapeutics, Inc. |
Chimeric antigen receptor for tumor targeting
|
|
CN119256075A
(zh)
|
2022-04-08 |
2025-01-03 |
菲特治疗公司 |
具有实体瘤靶向骨架的细胞及其用途
|
|
GB202205562D0
(en)
|
2022-04-14 |
2022-06-01 |
Nicoventures Trading Ltd |
Method
|
|
GB202205561D0
(en)
|
2022-04-14 |
2022-06-01 |
Nicoventures Trading Ltd |
Method
|
|
GB202206107D0
(en)
|
2022-04-27 |
2022-06-08 |
Nicoventures Trading Ltd |
Method
|
|
GB202206109D0
(en)
|
2022-04-27 |
2022-06-08 |
Nicoventures Trading Ltd |
Method
|
|
JP2025515030A
(ja)
|
2022-05-02 |
2025-05-13 |
フォンダジオン テレソン イーティーエス |
遺伝子編集用の相同性非依存性標的組込み
|
|
CA3256953A1
(en)
|
2022-05-09 |
2023-11-16 |
Regeneron Pharmaceuticals, Inc. |
VECTORS AND METHODS FOR IN VIVO ANTIBODY PRODUCTION
|
|
CN120303407A
(zh)
|
2022-05-17 |
2025-07-11 |
恩维洛普治疗有限责任公司 |
用于有效体内递送的组合物和方法
|
|
EP4525892A1
(en)
|
2022-05-19 |
2025-03-26 |
Lyell Immunopharma, Inc. |
Polynucleotides targeting nr4a3 and uses thereof
|
|
EP4279085A1
(en)
|
2022-05-20 |
2023-11-22 |
Mnemo Therapeutics |
Compositions and methods for treating a refractory or relapsed cancer or a chronic infectious disease
|
|
EP4278891A1
(en)
|
2022-05-20 |
2023-11-22 |
KWS SAAT SE & Co. KGaA |
Clubroot resistance and markers in brassica
|
|
GB202207774D0
(en)
|
2022-05-26 |
2022-07-13 |
Cambridge Entpr Ltd |
Modified plants
|
|
WO2023240212A2
(en)
|
2022-06-08 |
2023-12-14 |
Century Therapeutics, Inc. |
Genetically engineered cells having anti-cd133 / anti-egfr chimeric antigen receptors, and uses thereof
|
|
CA3257650A1
(en)
|
2022-06-08 |
2023-12-14 |
Century Therapeutics, Inc. |
Immunoeffector cells derived from genetically modified, multipotential stem cells with membrane IL-12 and their uses
|
|
CA3257424A1
(en)
|
2022-06-08 |
2023-12-14 |
Century Therapeutics, Inc. |
Genetically modified cells expressing variants of CD16 and NKG2D and their uses
|
|
AU2023290692A1
(en)
|
2022-06-17 |
2025-01-23 |
Crispr Therapeutics Ag |
LIPID NANOPARTICLES (LNPs)-BASED OCULAR DELIVERY
|
|
WO2023248145A1
(en)
|
2022-06-21 |
2023-12-28 |
Crispr Therapeutics Ag |
Compositions and methods for treating human immunodeficiency virus
|
|
US20230404003A1
(en)
|
2022-06-21 |
2023-12-21 |
Seminis Vegetable Seeds, Inc. |
Novel qtls conferring resistance to cucumber mosaic virus
|
|
WO2023248147A1
(en)
|
2022-06-21 |
2023-12-28 |
Crispr Therapeutics Ag |
Methods and compositions for in vivo editing of stem cells
|
|
CN119451992A
(zh)
|
2022-06-29 |
2025-02-14 |
克里斯珀医疗股份公司 |
靶向gpc-3的嵌合抗原受体和表达其的免疫细胞用于治疗用途
|
|
GB2621813A
(en)
|
2022-06-30 |
2024-02-28 |
Univ Newcastle |
Preventing disease recurrence in Mitochondrial replacement therapy
|
|
WO2024020360A1
(en)
|
2022-07-18 |
2024-01-25 |
Pairwise Plants Services, Inc. |
Mustard green plants named 'pwrg-1', 'pwrg-2,' and 'pwsgc'
|
|
WO2024020597A1
(en)
|
2022-07-22 |
2024-01-25 |
The Johns Hopkins University |
Dendrimer-enabled targeted intracellular crispr/cas system delivery and gene editing
|
|
WO2024023801A2
(en)
|
2022-07-29 |
2024-02-01 |
Crispr Therapeutics Ag |
Genetically engineered immune cells having disrupted transporter associated with antigen processing-1 (tap-1) gene
|
|
WO2024023804A2
(en)
|
2022-07-29 |
2024-02-01 |
Crispr Therapeutics Ag |
Genetically engineered immune cells having disrupted transporter associated with antigen processing binding protein (tapbp) gene
|
|
CN120659627A
(zh)
|
2022-07-29 |
2025-09-16 |
瑞泽恩制药公司 |
用于转铁蛋白受体(tfr)介导的脑和肌肉递送的组合物和方法
|
|
WO2024023802A2
(en)
|
2022-07-29 |
2024-02-01 |
Crispr Therapeutics Ag |
Genetically engineered immune cells having disrupted transporter associated with antigen processing-2 (tap-2) gene
|
|
LU502613B1
(en)
|
2022-08-01 |
2024-02-01 |
Plant Bioscience Ltd |
Methods of altering the starch granule profile in plants
|
|
CA3261296A1
(en)
|
2022-08-05 |
2024-02-08 |
Regeneron Pharmaceuticals, Inc. |
TDP-43 VARIANTS RESISTANT TO AGGREGATION
|
|
WO2024042199A1
(en)
|
2022-08-26 |
2024-02-29 |
KWS SAAT SE & Co. KGaA |
Use of paired genes in hybrid breeding
|
|
WO2024062388A2
(en)
|
2022-09-20 |
2024-03-28 |
Crispr Therapeutics Ag |
Genetically engineered immune cells expressing chimeric antigen receptor targeting cd20
|
|
WO2024062138A1
(en)
|
2022-09-23 |
2024-03-28 |
Mnemo Therapeutics |
Immune cells comprising a modified suv39h1 gene
|
|
WO2024064958A1
(en)
|
2022-09-23 |
2024-03-28 |
Lyell Immunopharma, Inc. |
Methods for culturing nr4a-deficient cells
|
|
WO2024064952A1
(en)
|
2022-09-23 |
2024-03-28 |
Lyell Immunopharma, Inc. |
Methods for culturing nr4a-deficient cells overexpressing c-jun
|
|
GB202214410D0
(en)
|
2022-09-30 |
2022-11-16 |
Ivy Farm Tech Limited |
genetically modified cells
|
|
WO2024077174A1
(en)
|
2022-10-05 |
2024-04-11 |
Lyell Immunopharma, Inc. |
Methods for culturing nr4a-deficient cells
|
|
WO2024079157A1
(en)
|
2022-10-11 |
2024-04-18 |
KWS SAAT SE & Co. KGaA |
Virus and insect resistance and markers in barley
|
|
JP2025536260A
(ja)
|
2022-10-11 |
2025-11-05 |
イェール ユニバーシティー |
細胞透過性抗体の組成物および使用方法
|
|
JP2025534904A
(ja)
|
2022-10-21 |
2025-10-21 |
キージーン ナムローゼ フェンノートシャップ |
修飾rnaによる植物細胞へのrnaトランスフェクション
|
|
WO2024102838A1
(en)
|
2022-11-09 |
2024-05-16 |
Century Therapeutics, Inc. |
Engineered interleukin-7 receptors and uses thereof
|
|
CN120435498A
(zh)
|
2022-11-10 |
2025-08-05 |
世纪治疗股份有限公司 |
具有抗-nectin4嵌合抗原受体的基因工程化细胞及其用途
|
|
JP2025538220A
(ja)
|
2022-11-14 |
2025-11-26 |
リジェネロン・ファーマシューティカルズ・インコーポレイテッド |
アストロサイトへの線維芽細胞増殖因子受容体3媒介送達のための組成物および方法
|
|
EP4619515A1
(en)
|
2022-11-17 |
2025-09-24 |
The Broad Institute, Inc. |
Prime editor delivery by aav
|
|
EP4626477A1
(en)
|
2022-12-01 |
2025-10-08 |
Yale University |
Stimuli-responsive traceless engineering platform for intracellular payload delivery
|
|
WO2024124044A1
(en)
|
2022-12-07 |
2024-06-13 |
The Brigham And Women’S Hospital, Inc. |
Compositions and methods targeting sat1 for enhancing anti¬ tumor immunity during tumor progression
|
|
WO2024121354A1
(en)
|
2022-12-08 |
2024-06-13 |
Keygene N.V. |
Duplex sequencing with covalently closed dna ends
|
|
WO2024138087A2
(en)
|
2022-12-23 |
2024-06-27 |
The Broad Institute, Inc. |
Methods and compositions for modulating cellular factors to increase prime editing efficiencies
|
|
EP4642225A1
(en)
|
2022-12-29 |
2025-11-05 |
Vilmorin & Cie |
Tomato plants resistant to resistance-breaking tswv strains and corresponding resistance genes
|
|
GB202219829D0
(en)
|
2022-12-29 |
2023-02-15 |
Ivy Farm Tech Limited |
Genetically manipulated cells
|
|
EP4652272A1
(en)
|
2023-01-18 |
2025-11-26 |
The Broad Institute Inc. |
Prime editing-mediated readthrough of premature termination codons (pert)
|
|
WO2024155745A1
(en)
|
2023-01-18 |
2024-07-25 |
The Broad Institute, Inc. |
Base editing-mediated readthrough of premature termination codons (bert)
|
|
GB202300905D0
(en)
|
2023-01-20 |
2023-03-08 |
Nicoventures Trading Ltd |
Method
|
|
EP4658061A1
(en)
|
2023-02-01 |
2025-12-10 |
United Beet Seeds |
Beet yellows virus resistance
|
|
WO2024170505A1
(en)
|
2023-02-13 |
2024-08-22 |
Institut National de la Santé et de la Recherche Médicale |
Methods of treatment of iron overload associated diseases
|
|
TW202440938A
(zh)
|
2023-02-15 |
2024-10-16 |
美商喬木生物技術公司 |
用於抑制微管解聚蛋白2(stmn2)轉錄物中異常剪接的基因編輯方法
|
|
GB202303077D0
(en)
|
2023-03-02 |
2023-04-19 |
Univ Oslo |
Brassica plants with improved seed retention
|
|
WO2024192108A1
(en)
|
2023-03-14 |
2024-09-19 |
Evolveimmune Therapeutics, Inc. |
Genetically modified car t cells and methods of making and using the same
|
|
US12419265B2
(en)
|
2023-03-27 |
2025-09-23 |
Redsea Science And Technology Inc. |
Tomato plant designated ‘X21-02’
|
|
WO2024206821A1
(en)
|
2023-03-31 |
2024-10-03 |
Briacell Therapeutics Corp. |
Methods for enhancing the immunogenicity of cellular vaccines
|
|
WO2024209000A1
(en)
|
2023-04-04 |
2024-10-10 |
Keygene N.V. |
Linkers for duplex sequencing
|
|
MX2024004405A
(es)
|
2023-04-14 |
2024-11-08 |
Seminis Vegetable Seeds Inc |
Métodos y composiciones de resistencia a peronospora en la espinaca
|
|
WO2024216116A1
(en)
|
2023-04-14 |
2024-10-17 |
Precision Biosciences, Inc. |
Muscle-specific expression cassettes
|
|
WO2024216118A1
(en)
|
2023-04-14 |
2024-10-17 |
Precision Biosciences, Inc. |
Muscle-specific expression cassettes
|
|
IT202300007968A1
(it)
|
2023-04-21 |
2024-10-21 |
Fond Telethon Ets |
Metodi di editing genomico e costrutti
|
|
WO2024226499A1
(en)
|
2023-04-24 |
2024-10-31 |
The Broad Institute, Inc. |
Compositions and methods for modifying fertility
|
|
WO2024223402A1
(en)
|
2023-04-24 |
2024-10-31 |
Institut National de la Santé et de la Recherche Médicale |
Biallelic gene mutations for the diagnosis of neonatal systemic hypertension
|
|
WO2024223900A1
(en)
|
2023-04-28 |
2024-10-31 |
Vilmorin & Cie |
Genetic determinants conferring improved tobrfv resistance
|
|
WO2024236547A1
(en)
|
2023-05-18 |
2024-11-21 |
Inceptor Bio, Llc |
Modified phagocytic cells expressing chimeric antigen receptors comprising a herpes virus entry mediator (hvem) co-stimulatory domain and uses thereof
|
|
WO2024243438A2
(en)
|
2023-05-23 |
2024-11-28 |
Omega Therapeutics, Inc. |
Compositions and methods for reducing cxcl9, cxcl10, and cxcl11 gene expression
|
|
WO2025003305A1
(en)
|
2023-06-28 |
2025-01-02 |
Vilmorin & Cie |
Pepper resistance to meloidogyne enterolobii
|
|
WO2025003461A1
(en)
|
2023-06-30 |
2025-01-02 |
Institut National de la Santé et de la Recherche Médicale |
Methods of treatment of metabolic disorders
|
|
WO2025022290A1
(en)
|
2023-07-21 |
2025-01-30 |
Crispr Therapeutics Ag |
Modulating expression of alas1 (5'-aminolevulinate synthase 1) gene
|
|
WO2025021893A1
(en)
|
2023-07-24 |
2025-01-30 |
Vilmorin & Cie |
Resistance to cysdv in melons
|
|
WO2025046513A1
(en)
|
2023-08-29 |
2025-03-06 |
Inceptor Bio, Llc |
Methods of manufacturing myeloid-derived cells from hematopoietic stem cells and compositions and uses thereof
|
|
EP4520334A1
(en)
|
2023-09-07 |
2025-03-12 |
Mnemo Therapeutics |
Methods and compositions for improving immune response
|
|
WO2025052001A1
(en)
|
2023-09-07 |
2025-03-13 |
Mnemo Therapeutics |
Methods and compositions for improving immune response
|
|
WO2025059215A1
(en)
|
2023-09-12 |
2025-03-20 |
Aadigen, Llc |
Methods and compositions for treating or preventing cancer
|
|
WO2025064408A1
(en)
|
2023-09-18 |
2025-03-27 |
The Broad Institute, Inc. |
Compositions and methods for treating cardiovascular disease
|
|
WO2025064678A2
(en)
|
2023-09-20 |
2025-03-27 |
The Broad Institute, Inc. |
Prime editing-mediated readthrough of frameshift mutations (perf)
|
|
GB202314578D0
(en)
|
2023-09-22 |
2023-11-08 |
Univ Manchester |
Methods of producing homoplasmic modified plants or parts thereof
|
|
WO2025101938A2
(en)
|
2023-11-10 |
2025-05-15 |
Century Therapeutics, Inc. |
Genetically engineered cells having multi-transmembrane domain chimeric antigen receptors utilizing g protein-coupled receptor scaffolds, and uses thereof
|
|
WO2025106626A1
(en)
|
2023-11-15 |
2025-05-22 |
Century Therapeutics, Inc. |
Genetically engineered cells expressing c-x-c chemokine receptor type 4, and uses thereof
|
|
WO2025128981A1
(en)
|
2023-12-14 |
2025-06-19 |
Sohm, Inc. |
Compositions and methods for genome editing
|
|
WO2025163107A1
(en)
|
2024-02-01 |
2025-08-07 |
Institut Gustave Roussy |
Immune cells defective for znf217 and uses thereof
|
|
WO2025186284A1
(en)
|
2024-03-05 |
2025-09-12 |
Vilmorin & Cie |
Increased yield in cucumber
|
|
WO2025186726A1
(en)
|
2024-03-05 |
2025-09-12 |
Crispr Therapeutics Ag |
Modulating expression of agt (angiotensinogen) gene
|
|
WO2025207798A1
(en)
|
2024-03-26 |
2025-10-02 |
Century Therapeutics, Inc. |
Genetically engineered cells having anti-cd123 chimeric antigen receptors, and uses thereof
|
|
WO2025207795A1
(en)
|
2024-03-26 |
2025-10-02 |
Juno Therapeutics, Inc. |
Genetically engineered cells having anti-cd33 / anti-cd123 chimeric antigen receptors, and uses thereof
|
|
WO2025215354A1
(en)
|
2024-04-08 |
2025-10-16 |
Ivy Farm Technologies Limited |
Method of culturing an animal cell
|
|
WO2025217398A1
(en)
|
2024-04-10 |
2025-10-16 |
Lyell Immunopharma, Inc. |
Methods for culturing cells with improved culture medium
|
|
US20250332260A1
(en)
|
2024-04-10 |
2025-10-30 |
Garuda Therapeutics, Inc. |
Immune compatible cells for allogeneic cell therapies to cover global, ethnic, or disease-specific populations
|
|
WO2025224715A1
(en)
|
2024-04-26 |
2025-10-30 |
King Abdullah Univeristy Of Science And Technology |
Methods for improving precise genome modification and reducing unwanted mutations by crispr-cas editing
|
|
WO2025235388A1
(en)
|
2024-05-06 |
2025-11-13 |
Regeneron Pharmaceuticals, Inc. |
Transgene genomic identification by nuclease-mediated long read sequencing
|
|
WO2025247951A1
(en)
|
2024-05-28 |
2025-12-04 |
Institut Gustave Roussy |
Fyn kinase inhibitors, combinations and uses thereof
|
|
US20250382627A1
(en)
|
2024-06-13 |
2025-12-18 |
J.R. Simplot Company |
Engineering remontant flowering in rosaceae
|