PL2785359T3 - Mezenchymalne komórki zrębowe i związane z nimi zastosowania - Google Patents
Mezenchymalne komórki zrębowe i związane z nimi zastosowaniaInfo
- Publication number
- PL2785359T3 PL2785359T3 PL12854438T PL12854438T PL2785359T3 PL 2785359 T3 PL2785359 T3 PL 2785359T3 PL 12854438 T PL12854438 T PL 12854438T PL 12854438 T PL12854438 T PL 12854438T PL 2785359 T3 PL2785359 T3 PL 2785359T3
- Authority
- PL
- Poland
- Prior art keywords
- mezenchymal
- related applications
- rigid cells
- rigid
- cells
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/14—Eye parts, e.g. lenses or corneal implants; Artificial eyes
- A61F2/141—Artificial eyes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/08—Devices or methods enabling eye-patients to replace direct visual perception by another kind of perception
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/30—Nerves; Brain; Eyes; Corneal cells; Cerebrospinal fluid; Neuronal stem cells; Neuronal precursor cells; Glial cells; Oligodendrocytes; Schwann cells; Astroglia; Astrocytes; Choroid plexus; Spinal cord tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/34—Muscles; Smooth muscle cells; Heart; Cardiac stem cells; Myoblasts; Myocytes; Cardiomyocytes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/36—Skin; Hair; Nails; Sebaceous glands; Cerumen; Epidermis; Epithelial cells; Keratinocytes; Langerhans cells; Ectodermal cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/37—Digestive system
- A61K35/39—Pancreas; Islets of Langerhans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/37—Digestive system
- A61K35/407—Liver; Hepatocytes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0647—Haematopoietic stem cells; Uncommitted or multipotent progenitors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0662—Stem cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0662—Stem cells
- C12N5/0668—Mesenchymal stem cells from other natural sources
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/069—Vascular Endothelial cells
- C12N5/0692—Stem cells; Progenitor cells; Precursor cells
-
- G—PHYSICS
- G06—COMPUTING OR CALCULATING; COUNTING
- G06F—ELECTRIC DIGITAL DATA PROCESSING
- G06F9/00—Arrangements for program control, e.g. control units
- G06F9/06—Arrangements for program control, e.g. control units using stored programs, i.e. using an internal store of processing equipment to receive or retain programs
- G06F9/46—Multiprogramming arrangements
- G06F9/54—Interprogram communication
- G06F9/542—Event management; Broadcasting; Multicasting; Notifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/115—Basic fibroblast growth factor (bFGF, FGF-2)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/125—Stem cell factor [SCF], c-kit ligand [KL]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/145—Thrombopoietin [TPO]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/155—Bone morphogenic proteins [BMP]; Osteogenins; Osteogenic factor; Bone inducing factor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/165—Vascular endothelial growth factor [VEGF]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/26—Flt-3 ligand (CD135L, flk-2 ligand)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2502/00—Coculture with; Conditioned medium produced by
- C12N2502/11—Coculture with; Conditioned medium produced by blood or immune system cells
- C12N2502/1171—Haematopoietic stem cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/02—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from embryonic cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/11—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from blood or immune system cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/28—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from vascular endothelial cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/50—Proteins
- C12N2533/54—Collagen; Gelatin
-
- G—PHYSICS
- G06—COMPUTING OR CALCULATING; COUNTING
- G06F—ELECTRIC DIGITAL DATA PROCESSING
- G06F2218/00—Aspects of pattern recognition specially adapted for signal processing
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Cell Biology (AREA)
- Developmental Biology & Embryology (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Virology (AREA)
- Hematology (AREA)
- Epidemiology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Vascular Medicine (AREA)
- Neurology (AREA)
- Rheumatology (AREA)
- Neurosurgery (AREA)
- Cardiology (AREA)
- Diabetes (AREA)
- Ophthalmology & Optometry (AREA)
- Dermatology (AREA)
- Heart & Thoracic Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pulmonology (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161565358P | 2011-11-30 | 2011-11-30 | |
| EP12854438.4A EP2785359B1 (en) | 2011-11-30 | 2012-11-30 | Mesenchymal stromal cells and uses related thereto |
| PCT/US2012/067464 WO2013082543A1 (en) | 2011-11-30 | 2012-11-30 | Mesenchymal stromal cells and uses related thereto |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2785359T3 true PL2785359T3 (pl) | 2018-12-31 |
Family
ID=48536141
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL12854438T PL2785359T3 (pl) | 2011-11-30 | 2012-11-30 | Mezenchymalne komórki zrębowe i związane z nimi zastosowania |
Country Status (19)
| Country | Link |
|---|---|
| US (5) | US8962321B2 (pl) |
| EP (2) | EP3449929B1 (pl) |
| JP (5) | JP2015500810A (pl) |
| KR (4) | KR102811933B1 (pl) |
| CN (2) | CN108478599B (pl) |
| AU (4) | AU2012345630A1 (pl) |
| CA (1) | CA2857545A1 (pl) |
| CY (1) | CY1122275T1 (pl) |
| DK (1) | DK2785359T3 (pl) |
| ES (1) | ES2690212T3 (pl) |
| HR (1) | HRP20181515T1 (pl) |
| HU (1) | HUE040566T2 (pl) |
| LT (1) | LT2785359T (pl) |
| PL (1) | PL2785359T3 (pl) |
| PT (1) | PT2785359T (pl) |
| RS (1) | RS57886B1 (pl) |
| SI (1) | SI2785359T1 (pl) |
| TW (5) | TWI812867B (pl) |
| WO (1) | WO2013082543A1 (pl) |
Families Citing this family (92)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2007238660C1 (en) | 2006-04-14 | 2013-11-07 | Astellas Institute For Regenerative Medicine | Hemangio-colony forming cells |
| US20110086424A1 (en) | 2008-05-06 | 2011-04-14 | Advanced Cell Technology, Inc. | Methods for producing enucleated erythroid cells derived from pluripotent stem cells |
| US8961956B2 (en) | 2011-11-30 | 2015-02-24 | Ocata Therapeutics, Inc. | Mesenchymal stromal cells and uses related thereto |
| PL2785359T3 (pl) | 2011-11-30 | 2018-12-31 | Astellas Institute For Regenerative Medicine | Mezenchymalne komórki zrębowe i związane z nimi zastosowania |
| EP2872619B1 (en) | 2012-07-11 | 2018-02-14 | Imstem Biotechnology Inc. | Mesenchymal-like stem cells derived from human embryonic stem cells, methods and uses thereof |
| CN104471059B (zh) | 2012-07-12 | 2018-04-17 | 珠海横琴爱姆斯坦生物科技有限公司 | 人胚胎干细胞衍生的间充质样干细胞、方法及其应用 |
| CA2896053A1 (en) | 2012-12-21 | 2014-06-26 | Ocata Therapeutics, Inc. | Methods for production of platelets from pluripotent stem cells and compositions thereof |
| KR101669124B1 (ko) * | 2013-07-11 | 2016-10-25 | 서울대학교병원 | 인간 배아줄기세포에서 유래된 중간엽 줄기세포를 유효성분으로 함유하는 간섬유화 또는 간경화 예방 및 치료용 조성물 |
| ES2615396T3 (es) | 2013-08-22 | 2017-06-07 | Georg-August-Universität Göttingen Stiftung Öffentlichen Rechts Universitätsmedizin | Método para producir músculo cardiaco por ingeniería (EHM) |
| US9724365B2 (en) * | 2013-11-18 | 2017-08-08 | University of Pittsburgh—of the Commonwealth System of Higher Education | Microsphere-based delivery and ex vivo manipulation of dendritic cells for autoimmune therapies |
| WO2015189063A1 (en) * | 2014-06-10 | 2015-12-17 | Mesoblast International Sàrl | Treatment of immune disorders |
| JP6452107B2 (ja) * | 2014-09-05 | 2019-01-16 | 国立大学法人 東京大学 | 糖尿病性皮膚潰瘍治療のための多能性幹細胞 |
| CN104232573B (zh) * | 2014-09-11 | 2017-01-11 | 安沂华 | 一种生长培养基及其用途和培养脐带间充质干细胞的方法 |
| US20160095885A1 (en) * | 2014-10-01 | 2016-04-07 | WibiWorks Therapeutics, Inc. | Induction Medium & Methods for Stem Cell Culture & Therapy |
| CN104531613B (zh) * | 2014-11-17 | 2017-12-19 | 中国农业科学院北京畜牧兽医研究所 | Wip1敲除在促进小鼠骨髓间充质干细胞迁移中的应用 |
| CA3247653A1 (en) * | 2014-12-23 | 2025-10-31 | Mesoblast International Sarl | Method for treating heart failure |
| EP3869195B1 (en) | 2015-03-23 | 2024-03-20 | Astellas Institute for Regenerative Medicine | Improved assays for potency of human retinal pigment epithelium (rpe) cells and photoreceptor progenitors |
| CN108138144A (zh) * | 2015-08-05 | 2018-06-08 | 细胞治疗神经科学有限公司 | 视网膜色素上皮细胞的制备 |
| KR102411018B1 (ko) | 2015-08-18 | 2022-06-20 | 아스텔라스 인스티튜트 포 리제너러티브 메디슨 | 임상 제제 |
| US20180284142A1 (en) * | 2015-09-29 | 2018-10-04 | Celularity, Inc. | Cell potency assay |
| WO2017060240A1 (en) * | 2015-10-05 | 2017-04-13 | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. | Method and culture medium for ex vivo culturing of epidermis-derived stem cells |
| CA3004296A1 (en) * | 2015-11-04 | 2017-05-11 | The Board Of Regents Of The University Of Texas System | Enrich and amplify highly potent human mesenchymal stem cells from elderly cell populations |
| CN108289915A (zh) * | 2015-11-24 | 2018-07-17 | 日本乐敦制药株式会社 | 包含脂肪组织来源基质细胞的肝病治疗剂及其制造方法 |
| CN105326864A (zh) * | 2015-11-30 | 2016-02-17 | 奥思达干细胞有限公司 | 一种治疗系统性红斑狼疮的干细胞制剂及其制备方法 |
| US10383895B2 (en) * | 2016-02-18 | 2019-08-20 | Viera Bioscience, Inc. | Stimulation of therapeutic angiogenesis by T regulatory cells |
| CN105671000A (zh) * | 2016-03-02 | 2016-06-15 | 深圳爱生再生医学科技有限公司 | 重组间充质干细胞及其制备方法和应用 |
| US10758574B2 (en) | 2016-04-28 | 2020-09-01 | The Board Of Trustees Of The Leland Stanford Junior University | Cartilage cells with a high regenerative potential and low immune response for use in cellular therapy |
| EP3481967A4 (en) * | 2016-07-11 | 2020-04-22 | Bonus Therapeutics Ltd. | Cell compositions for tissue regeneration |
| CN106267161A (zh) * | 2016-09-30 | 2017-01-04 | 广州赛莱拉干细胞科技股份有限公司 | 一种干细胞制剂及其制备方法和应用 |
| CN106265899A (zh) * | 2016-09-30 | 2017-01-04 | 广州赛莱拉干细胞科技股份有限公司 | 一种组合物及其在制备改善慢性鼻炎的产品中的应用 |
| CN106520686A (zh) * | 2016-10-11 | 2017-03-22 | 海南博鳌龄迈迪精准医学研究院有限公司 | 脂肪间充质干细胞的培养方法 |
| CN106479968A (zh) * | 2016-10-11 | 2017-03-08 | 海南博鳌龄迈迪精准医学研究院有限公司 | 脐带间充质干细胞的培养方法 |
| KR101971322B1 (ko) * | 2016-10-17 | 2019-04-23 | 사회복지법인 삼성생명공익재단 | Socs의 발현 또는 활성 억제를 이용한 고효능 줄기세포 선별방법 |
| AU2017354272A1 (en) * | 2016-11-03 | 2019-05-23 | Exostem Biotec Ltd. | Mesenchymal stem cells populations, their products, and use thereof |
| CN106581760A (zh) * | 2016-11-08 | 2017-04-26 | 华南生物医药研究院 | 增强细胞活性的特殊处理方法 |
| CN106619721A (zh) * | 2016-11-08 | 2017-05-10 | 中国人民解放军军事医学科学院野战输血研究所 | 一种增强细胞活性的新方法 |
| CN106563161A (zh) * | 2016-11-08 | 2017-04-19 | 华南生物医药研究院 | 可用于美容的新型药物组合剂 |
| KR102390909B1 (ko) * | 2016-12-19 | 2022-04-26 | 주식회사 파이안바이오테크놀로지 | 미토콘드리아를 포함하는 허혈성 질환 예방 또는 치료용 조성물 |
| EP3824906A1 (en) | 2016-12-21 | 2021-05-26 | Amgen Inc. | Anti-tnf alpha antibody formulations |
| GB201703058D0 (en) * | 2017-02-24 | 2017-04-12 | Ucl Business Plc | Biomarkers |
| CN110494556B (zh) * | 2017-04-03 | 2024-04-30 | 株式会社钟化 | 包含间充质系干细胞的细胞群、其制造方法、以及医药组合物 |
| WO2018207918A1 (ja) * | 2017-05-12 | 2018-11-15 | 国立大学法人 東京医科歯科大学 | 移植効率を向上させる間葉系幹細胞の純化方法 |
| JP7712643B2 (ja) * | 2017-06-19 | 2025-07-24 | 国立大学法人東北大学 | 表皮水疱症の治療剤 |
| CN107490701B (zh) * | 2017-08-17 | 2021-09-14 | 上海集技生物技术有限公司 | 一种基于局部照射的全身性骨损伤模型的建立及病理机制分析的方法 |
| CN107714726A (zh) * | 2017-10-16 | 2018-02-23 | 中国科学院广州生物医药与健康研究院 | 一种重塑骨髓微环境的方法 |
| GB2568603A (en) * | 2017-11-06 | 2019-05-22 | King S College London | Therapeutic substances, their preparation and diagnostic procedure |
| KR102095628B1 (ko) * | 2018-01-05 | 2020-04-01 | 재단법인 아산사회복지재단 | 유도만능 줄기세포 유래 중간엽 줄기세포 및 이로부터 유래된 엑소좀을 포함하는 피부질환의 개선, 예방 또는 치료용 조성물 |
| WO2019158712A1 (en) * | 2018-02-16 | 2019-08-22 | Nextcell Pharma Ab | Allogeneic composition |
| WO2019171386A1 (en) * | 2018-03-07 | 2019-09-12 | The Medical Research Infrastructure And Health Services Fund Of The Tel-Aviv Medical Center | Compositions and methods for treating age-related macular degeneration |
| KR20210021358A (ko) * | 2018-06-15 | 2021-02-25 | 파르도 루이스 마리나스 | 약제학적 피부과 조성물 및 그 용도 |
| KR102337954B1 (ko) * | 2018-08-16 | 2021-12-10 | 차의과학대학교 산학협력단 | 뇌졸중 치료용 조성물 및 이를 스크리닝하는 방법 |
| CN109082409A (zh) * | 2018-09-14 | 2018-12-25 | 四川新生命干细胞科技股份有限公司 | 一种组织修复能力强的脂肪干细胞分离培养及筛选方法 |
| CN109182262A (zh) * | 2018-09-25 | 2019-01-11 | 深圳市五零生命科技有限公司 | 一种间充质干细胞无血清培养基 |
| CA3120576A1 (en) * | 2018-11-26 | 2020-06-04 | Massachusetts Institute Of Technology | Compositions and methods for immune tolerance |
| CN109342739A (zh) * | 2018-11-27 | 2019-02-15 | 上海科医联创生物科技有限公司 | 一种鉴定间充质干细胞纯度的方法 |
| CN109609584A (zh) * | 2018-12-10 | 2019-04-12 | 天津长和生物技术有限公司 | 间充质干细胞免疫调节能力的检测方法 |
| JP7628499B2 (ja) * | 2019-02-27 | 2025-02-10 | 武田薬品工業株式会社 | 同種異系療法のための改良された幹細胞集団 |
| KR20210139259A (ko) * | 2019-03-12 | 2021-11-22 | 글로벌 스템 셀 테크놀로지 | 면역조절 중간엽 줄기 세포 |
| CN113557025A (zh) | 2019-03-14 | 2021-10-26 | 北海道公立大学法人札幌医科大学 | 肌萎缩侧索硬化症治疗用医药组合物 |
| JP7391181B2 (ja) | 2019-07-26 | 2023-12-04 | プレクソジェン インコーポレイテッド | 人工多能性幹細胞(iPSC)由来間葉系幹細胞の前駆細胞、及びその製造方法 |
| CN110305839A (zh) * | 2019-08-02 | 2019-10-08 | 陕西佰傲干细胞再生医学有限公司 | 间充质干细胞无血清培养基 |
| TW202122577A (zh) | 2019-08-28 | 2021-06-16 | 安斯泰來再生醫藥協會 | 治療血管疾病之方法 |
| US20220288131A1 (en) | 2019-08-28 | 2022-09-15 | Astellas Institute For Regenerative Medicine | Compositions and methods of treating vascular diseases |
| CN110564674B (zh) * | 2019-09-29 | 2021-05-11 | 广东工业大学 | 一种干细胞铺底工作液及其应用 |
| WO2021072595A1 (zh) * | 2019-10-14 | 2021-04-22 | 玛旺干细胞医学生物科技股份有限公司 | 间充质干细胞在治疗听力障碍上的医药用途 |
| RU2740152C1 (ru) * | 2020-01-09 | 2021-01-13 | Федеральное государственное бюджетное научное учреждение "Федеральный исследовательский центр "Красноярский научный центр Сибирского отделения Российской академии наук" (ФИЦ КНЦ СО РАН) | Способ активации пролиферативного ответа фибробластоподобных клеток стромально-васкулярной фракции жировой ткани |
| CN114829583A (zh) * | 2020-02-25 | 2022-07-29 | 上海大学 | 间充质干细胞在治疗重症covid19肺炎中的用途 |
| WO2021210515A1 (ja) * | 2020-04-13 | 2021-10-21 | 国立大学法人東海国立大学機構 | 腎臓中のcd25陽性の制御性t細胞増加剤 |
| JP2023524660A (ja) * | 2020-04-28 | 2023-06-13 | ファクター バイオサイエンス インコーポレイテッド | 間葉系幹細胞療法 |
| EP3909594A1 (en) * | 2020-05-14 | 2021-11-17 | Bernat Soria Escoms | Mesenchymal stromal cells for the treatment of covid-19 and other inflammatory, autoimmune and degenerative diseases |
| CN111518761B (zh) * | 2020-05-25 | 2022-04-29 | 青岛瑞思德生物科技有限公司 | 一种间充质干细胞体外筛选、激活、扩增、冻存及其细胞库建立的方法 |
| WO2022004938A1 (ko) * | 2020-06-30 | 2022-01-06 | 주식회사 미래셀바이오 | 유사 중간엽 줄기세포의 제조방법 |
| EP3945133A1 (en) * | 2020-07-29 | 2022-02-02 | Georg-August-Universität Göttingen | Mass production of human pluripotent stem cell derived cardiac stromal cell |
| CN112826833A (zh) * | 2020-07-30 | 2021-05-25 | 中国人民解放军总医院第五医学中心 | 间充质干细胞在制备新冠肺炎引起的肺损伤修复药物中的应用 |
| CN111808812B (zh) * | 2020-08-31 | 2020-12-15 | 首都医科大学附属北京友谊医院 | 一种用于多能干细胞向造血干细胞分化的材料和方法 |
| US20230405051A1 (en) * | 2020-10-22 | 2023-12-21 | The Catholic University Of Korea Industry-Academic Cooperation Foundation | Pharmaceutical composition for prevention or treatment of rheumatoid arthritis, comprising, as active ingredient, stem cells having expression of specific genes increased or decreased therein |
| WO2022234998A1 (ko) * | 2021-05-07 | 2022-11-10 | 의료법인 성광의료재단 | 골 분화능 기능강화 중간엽 줄기세포 및 이의 용도 |
| EP4366744A1 (en) * | 2021-07-08 | 2024-05-15 | Boehringer Ingelheim Veterinary Medicine Belgium | Mesenchymal stem cells for use in the treatment of chronic gingivostomatitis |
| CN113717972B (zh) * | 2021-08-16 | 2022-07-01 | 南通市肿瘤医院 | MYADM靶向的siRNA及其应用 |
| WO2023064404A1 (en) * | 2021-10-12 | 2023-04-20 | Mechanogenic K.K. | Anti-aging composition using mesenchymal stem cells and methods thereof |
| US20230257714A1 (en) * | 2022-02-07 | 2023-08-17 | Smartcella Solutions Ab | Methods and compositions for generating human induced mesenchymal stem cells |
| CN114984051A (zh) * | 2022-06-27 | 2022-09-02 | 广州惠善医疗技术有限公司 | 间充质干细胞在制备治疗炎症及免疫相关疾病的药物中的应用 |
| WO2024007038A2 (en) * | 2022-07-01 | 2024-01-04 | Northwestern University | Compositions and methods for the treatment of intestinal inflammation |
| AU2023310144A1 (en) | 2022-07-18 | 2025-01-02 | Astellas Institute For Regenerative Medicine | Methods of treating brain injury |
| CN115305234B (zh) * | 2022-09-28 | 2023-01-17 | 呈诺再生医学科技(北京)有限公司 | 一种制备间充质干细胞的方法、间充质干细胞和应用 |
| EP4545630A4 (en) * | 2023-01-27 | 2026-08-19 | Rainbow Inc | METHOD FOR REGULATING CELL PROLIFERATION IN AN AUTOMATIC CULTURE DEVICE |
| TW202434721A (zh) * | 2023-02-14 | 2024-09-01 | 國立大學法人山口大學 | 細胞群、三維細胞培養體、醫藥組成物、胞泌體及製作此細胞群的方法 |
| US20240294925A1 (en) * | 2023-03-02 | 2024-09-05 | University Of South Florida | Method of Treatment for Auditory Dysfunction |
| CN116836920B (zh) * | 2023-08-21 | 2024-05-24 | 广东横琴粤澳深度合作区齐美国际干细胞医院有限公司 | 一种无血清培养基及其制备间充质干细胞的方法 |
| CN117210528B (zh) * | 2023-09-12 | 2024-08-20 | 长沙干细胞与再生医学工业技术研究院有限公司 | 一种综合评估间充质干细胞免疫调控能力的方法 |
| WO2025084581A1 (ko) * | 2023-10-18 | 2025-04-24 | 이화여자대학교 산학협력단 | 편도 유래 중간엽 줄기세포를 포함하는 복막 섬유증의 개선, 예방 또는 치료용 조성물 |
| CN121137073B (zh) * | 2025-11-17 | 2026-05-01 | 上海兴瑞一达生物科技有限公司 | 一种抗IL-11抗体修饰的Treg细胞的制备方法及其应用 |
Family Cites Families (159)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6416581A (en) * | 1987-07-09 | 1989-01-20 | Rikagaku Kenkyusho | Frozen animal cell and production thereof |
| US5128259A (en) | 1989-10-27 | 1992-07-07 | Hahnemann University | Factor-dependent hematopoietic cell line exhibiting epo-induced erythrocyte maturation |
| US5635387A (en) | 1990-04-23 | 1997-06-03 | Cellpro, Inc. | Methods and device for culturing human hematopoietic cells and their precursors |
| US5599705A (en) | 1993-11-16 | 1997-02-04 | Cameron; Robert B. | In vitro method for producing differentiated universally compatible mature human blood cells |
| WO1995017500A1 (en) | 1993-12-23 | 1995-06-29 | Abs Global, Inc. | Embryonic stem cells as nuclear donors and nuclear transfer techniques to produce chimeric and transgenic animals |
| US5874301A (en) | 1994-11-21 | 1999-02-23 | National Jewish Center For Immunology And Respiratory Medicine | Embryonic cell populations and methods to isolate such populations |
| US5914268A (en) | 1994-11-21 | 1999-06-22 | National Jewish Center For Immunology & Respiratory Medicine | Embryonic cell populations and methods to isolate such populations |
| CA2278847A1 (en) | 1997-01-31 | 1998-08-06 | Hemosol Inc. | Method for the production of selected lymphocytes |
| AU7499498A (en) | 1997-05-21 | 1998-12-11 | Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The | Methods and compositions for making dendritic cells from expanded populations ofmonocytes and for activating t cells |
| US6429012B1 (en) | 1997-10-06 | 2002-08-06 | Viacell, Inc. | Cell population containing non-fetal hemangioblasts and method for producing same |
| US6030836A (en) | 1998-06-08 | 2000-02-29 | Osiris Therapeutics, Inc. | Vitro maintenance of hematopoietic stem cells |
| WO1999067360A2 (en) | 1998-06-25 | 1999-12-29 | Hemosol Inc. | Media and methods for expansion of erythroid stem cells for the production of hemoglobin |
| EP1105463A1 (en) | 1998-08-24 | 2001-06-13 | t. Breeders, Inc. | Cell population containing non-fetal hemangioblasts and method for producing same |
| US20110171185A1 (en) | 1999-06-30 | 2011-07-14 | Klimanskaya Irina V | Genetically intact induced pluripotent cells or transdifferentiated cells and methods for the production thereof |
| JP2003512052A (ja) | 1999-10-15 | 2003-04-02 | アドバンスド セル テクノロジー、インコーポレイテッド | 分化前駆細胞及び系統欠失胚性幹細胞の産生方法 |
| AU1778001A (en) | 1999-11-17 | 2001-05-30 | University Of Rochester | Human ex vivo immune system |
| JP2003533976A (ja) | 2000-01-07 | 2003-11-18 | オレゴン ヘルス アンド サイエンス ユニバーシティ | 胚分割による霊長類子孫のクローン性増殖 |
| US7795026B2 (en) | 2000-01-21 | 2010-09-14 | The Johns Hopkins University School Of Medicine | Methods for obtaining human embryoid body-derived cells |
| US6602711B1 (en) | 2000-02-21 | 2003-08-05 | Wisconsin Alumni Research Foundation | Method of making embryoid bodies from primate embryonic stem cells |
| JP2004504834A (ja) | 2000-08-01 | 2004-02-19 | イスム リサーチ ディベロップメント カンパニー | 胚性細胞の定方向分化 |
| EP1320390A2 (en) | 2000-09-18 | 2003-06-25 | Organogenesis Inc. | Bioengineered flat sheet graft prosthesis and its use |
| AU2002335610C1 (en) | 2001-01-29 | 2008-09-25 | Hemogenix, Inc. | High-throughput stem cell assay of hematopoietic stem and progenitor cell proliferation |
| WO2002078449A2 (en) | 2001-04-02 | 2002-10-10 | Advanced Cell Technology, Inc. | Method for facilitating the production of differentiated cell types and tissues from embryonic and adult pluripotent and multipotent cells |
| KR20020083634A (ko) | 2001-04-27 | 2002-11-04 | 크레아젠 주식회사 | 수지상 세포를 포함하는 자가면역 질환의 치료용 약제학적조성물 및 이를 이용한 치료방법 |
| WO2002092756A2 (en) | 2001-05-15 | 2002-11-21 | Rappaport Family Institute For Research In The Medical Sciences | Insulin producing cells derived from human embryonic stem cells |
| US20050042751A1 (en) | 2001-10-31 | 2005-02-24 | Michel Goldman | Generation and use of new types of dendritic cells |
| WO2003040319A2 (en) | 2001-11-02 | 2003-05-15 | Wisconsin Alumni Research Foundation | Endothelial cells derived from primate embryonic stem cells |
| US8021876B2 (en) | 2001-11-15 | 2011-09-20 | Children's Medical Center Corporation | Methods of isolation, expansion and differentiation of fetal stem cells from chorionic villus, amniotic fluid, and placenta and therapeutic uses thereof |
| US20030232430A1 (en) | 2001-11-26 | 2003-12-18 | Advanced Cell Technology | Methods for making and using reprogrammed human somatic cell nuclei and autologous and isogenic human stem cells |
| CN1630716A (zh) | 2001-12-07 | 2005-06-22 | 杰龙公司 | 人胚胎干细胞衍生的造血细胞 |
| WO2003080116A1 (en) | 2002-03-21 | 2003-10-02 | University Of Florida | Modulating angiogenesis |
| AU2003248609A1 (en) | 2002-07-12 | 2004-02-02 | Agency For Science, Technology And Research | Hemangioblast progenitor cells |
| US20040052771A1 (en) | 2002-07-12 | 2004-03-18 | Lim Sai Kiang | Hemangioblast progenitor cells |
| AR047712A1 (es) | 2002-09-07 | 2006-02-15 | Royal Veterinary College | Metodo de tratamiento de una lesion de tejido esqueletico blando natural administrando una composicion de celulas madre mesenquimatosas |
| WO2004029231A1 (en) | 2002-09-26 | 2004-04-08 | Institut National De La Sante Et De La Recherche Medicale | Compositions and methods for amplification of human stem cells |
| US7427603B2 (en) | 2002-09-26 | 2008-09-23 | The Children's Medical Center Corporation | Method of enhancing proliferation and/or hematopoietic differentiation of stem cells |
| US20050054096A1 (en) | 2002-11-06 | 2005-03-10 | Piniella Carlos J. | Pluripotent cells from monocytes, and methods of making and using pluripotent cells |
| US20040156878A1 (en) | 2003-02-11 | 2004-08-12 | Alireza Rezania | Implantable medical device seeded with mammalian cells and methods of treatment |
| US20050032210A1 (en) | 2003-03-18 | 2005-02-10 | Kirin Beer Kabushiki Kaisha | Method of preparing immuno-regulatory dendritic cells and the use thereof |
| WO2004098285A2 (en) | 2003-05-08 | 2004-11-18 | Cellartis Ab | Cryopreservation of human blastocyst-derived stem cells by use of a closed straw vitrification method |
| US20040229350A1 (en) | 2003-05-12 | 2004-11-18 | Nikolai Strelchenko | Morula derived embryonic stem cells |
| WO2005040391A1 (en) | 2003-10-27 | 2005-05-06 | Murdoch Childrens Research Institute | Compositions and methods for differentiating stem cells |
| WO2005049812A1 (en) | 2003-11-19 | 2005-06-02 | Australian Stem Cell Centre Limited | Methods for producing blood products from pluripotent cells in cell culture |
| AU2004308927A1 (en) | 2003-12-19 | 2005-07-14 | Viacell, Inc. | Use of human cord blood-derived pluripotent cells for the treatment of disease |
| CN1286970C (zh) | 2003-12-30 | 2006-11-29 | 上海伯瑞生物技术发展有限公司 | 由脐血cd34+细胞体外诱导生成巨核细胞的方法 |
| CA2552288C (en) | 2004-01-02 | 2015-02-24 | Advanced Cell Technology, Inc. | Novel culture systems for ex vivo development |
| KR100535326B1 (ko) | 2004-01-20 | 2005-12-09 | 한국생명공학연구원 | 줄기 세포로부터 자연살해 세포로의 분화 조절용 유전자를유효성분으로 포함하는 분화 조절제 |
| CA2937099A1 (en) | 2004-01-23 | 2005-08-04 | Astellas Institute For Regenerative Medicine | Improved modalities for the treatment of degenerative diseases of the retina |
| US7794704B2 (en) | 2004-01-23 | 2010-09-14 | Advanced Cell Technology, Inc. | Methods for producing enriched populations of human retinal pigment epithelium cells for treatment of retinal degeneration |
| US20050266556A1 (en) | 2004-02-09 | 2005-12-01 | Yoder Mervin C | Isolation, expansion and use of clonogenic endothelial progenitor cells |
| CA2564679C (en) | 2004-03-22 | 2015-06-23 | Osiris Therapeutics, Inc. | Mesenchymal stem cells and uses therefor |
| US20080095749A1 (en) * | 2004-03-22 | 2008-04-24 | Sudeepta Aggarwal | Mesenchymal stem cells and uses therefor |
| WO2005097979A2 (en) | 2004-03-31 | 2005-10-20 | Newlink Genetics Corporation | Methods and compositions for obtaining hematopoietic stem cells derived from embryonic stem cells and uses thereof |
| US7592176B2 (en) | 2004-05-07 | 2009-09-22 | Wisconsin Alumni Research Foundation | Method of forming mesenchymal stem cells from embryonic stem cells |
| NZ551828A (en) * | 2004-05-12 | 2009-03-31 | Inst Medical W & E Hall | A method of cell isolating a homogenous population of mammary stem cells using specific cell surface marker proteins |
| CA2566561C (en) | 2004-06-04 | 2013-01-08 | Universite Pierre Et Marie Curie - Paris Vi | A method for producing red blood cells |
| EP1775343A4 (en) | 2004-06-24 | 2007-11-14 | Dnavec Research Inc | ANTITUM-AGENT WITH DENDRITIC CELL WITH THE TRANSFECTED RNA VIRUS |
| TR201900968T4 (tr) | 2004-09-24 | 2019-02-21 | Mesoblast Inc | Multipotansiyel genleşmiş mezenkimal prekürsör hücre soyu (memp) ve bunların kullanımı. |
| NZ554866A (en) | 2004-11-01 | 2010-12-24 | Wisconsin Alumni Res Found | Platelets from stem cells |
| US7893315B2 (en) | 2004-11-04 | 2011-02-22 | Advanced Cell Technology, Inc. | Derivation of embryonic stem cells and embryo-derived cells |
| US8492148B2 (en) | 2005-02-23 | 2013-07-23 | Foundation For Biomedical Research & Innovation | Method for amplification of endothelial progenitor cell in vitro |
| US20080166751A1 (en) | 2005-02-23 | 2008-07-10 | Takayuki Asahara | Method of Analyzing Dynamics in the Differentiation of Vascular Endothelial Progenitor Cells |
| JP2006230316A (ja) * | 2005-02-25 | 2006-09-07 | Japan Health Science Foundation | 瘢痕のない創傷治癒能を有する細胞およびその調製方法 |
| EP1863905B1 (en) | 2005-03-17 | 2016-01-20 | UCL Business PLC | Method for activating natural killer cells by tumour cell preparations in vitro |
| AU2006249640C1 (en) | 2005-04-08 | 2016-10-13 | Coimmune, Inc. | Dendritic cell compositions and methods |
| CA2609541A1 (en) | 2005-05-27 | 2006-12-07 | Advanced Cell Technology, Inc. | Methods for identifying ligands for stem cells and cells derived therefrom |
| KR20080015033A (ko) | 2005-06-01 | 2008-02-15 | 위스콘신 얼럼나이 리서어치 화운데이션 | 배아 줄기 세포로부터 가지 세포를 형성하는 방법 |
| WO2007005595A1 (en) | 2005-07-05 | 2007-01-11 | The New England Medical Center Hospitals, Inc. | Pregnancy-associated progenitor cells |
| EP1909565A2 (en) | 2005-08-03 | 2008-04-16 | Interface Multigrad Technology (IMT) Ltd. | Somatic cells for use in cell therapy |
| ES2933478T3 (es) | 2005-08-03 | 2023-02-09 | Astellas Inst For Regenerative Medicine | Métodos mejorados de reprogramación de células somáticas animales |
| US9121008B2 (en) | 2005-08-31 | 2015-09-01 | University Of Utah Research Foundation | Development of natural killer cells and functional natural killer cell lines |
| WO2008020815A1 (en) | 2006-08-15 | 2008-02-21 | Agency For Science, Technology And Research | Mesenchymal stem cell conditioned medium |
| EP1789435B1 (en) | 2005-09-12 | 2010-02-24 | Industry Foundation of Chonnam National University | A method for production of mature natural killer cell |
| JP2007089432A (ja) | 2005-09-27 | 2007-04-12 | Reprocell Inc | 幹細胞由来血小板産生増加法 |
| PT1941027E (pt) | 2005-09-28 | 2014-10-09 | Ipd Therapeutics B V | Métodos e meios para proliferação de células estaminais e subsequente geração e expansão de células progenitoras, bem como produção de células efectoras como produtos terapêuticos clínicos |
| US20090271335A1 (en) | 2005-10-20 | 2009-10-29 | Advanced Cell Technology, Inc. | Totipotent, Nearly Totipotent or Pluripotent Mammalian Cells Homozygous or Hemizygous for One or More Histocompatibility Antigent Genes |
| AU2006306809B2 (en) | 2005-10-24 | 2012-07-19 | Agency For Science, Technology And Research | Methods of specifying mesodermal, endodermal and mesoendodermal cell fates |
| WO2007062198A1 (en) | 2005-11-21 | 2007-05-31 | Advanced Cell Technology, Inc. | Methods to accelerate the isolation of novel cell strains from pluripotent stem cells and cells obtained thereby |
| CN101370930A (zh) | 2006-01-13 | 2009-02-18 | 奥西里斯治疗公司 | 表达TNF-α受体的间充质干细胞 |
| EP1989296A2 (en) | 2006-02-09 | 2008-11-12 | Wisconsin Alumni Research Foundation | Erythroid cells producing adult-type -hemoglobin generated from human embryonic stem cells |
| JP2009531021A (ja) * | 2006-02-16 | 2009-09-03 | フォンダッチォーネ・セントロ・サン・ラファエル・デル・モンテ・タボール | 骨格筋周囲血管芽細胞および心筋中胚葉性血管芽細胞、それらの単離および使用方法 |
| US20090232777A1 (en) * | 2006-03-01 | 2009-09-17 | Evy Lundgren-Akerlund | Expansion and Differentiation of Mesenchymal Stem Cells |
| CN101045915A (zh) | 2006-03-29 | 2007-10-03 | 旭日干 | 一种卵母细胞生发泡移植技术 |
| CN101045914A (zh) | 2006-03-29 | 2007-10-03 | 中国人民解放军军事医学科学院野战输血研究所 | 体外诱导造血干/祖细胞分化为成熟红细胞的方法与应用 |
| AU2013201444B2 (en) | 2006-04-14 | 2015-01-22 | Astellas Institute For Regenerative Medicine | Hemangio-colony forming cells |
| AU2007238660C1 (en) | 2006-04-14 | 2013-11-07 | Astellas Institute For Regenerative Medicine | Hemangio-colony forming cells |
| NZ572842A (en) | 2006-04-14 | 2012-01-12 | Advanced Cell Tech Inc | Hemangio-colony forming cells |
| KR100791487B1 (ko) * | 2006-05-29 | 2008-01-03 | 연세대학교 산학협력단 | 제대혈로부터 간엽줄기세포의 분리 및 배양 방법 |
| US20070298496A1 (en) | 2006-06-23 | 2007-12-27 | Hung-Chih Kuo | Method of deriving pluripotent stem cells from a single blastomere |
| PL2578081T3 (pl) | 2006-10-11 | 2016-09-30 | Kompozycje, sposoby i urządzenia do leczenia chorób wątroby | |
| WO2008067142A2 (en) | 2006-11-08 | 2008-06-05 | Wisconsin Alumni Research Foundation | In vitro differentiation of hematopoietic cells from primate embryonic stem cells |
| EP2088190A4 (en) | 2006-11-09 | 2011-01-05 | Japan Government | METHOD FOR THE CULTURE AND PASSING OF AN EMBRYONAL PRIMATIVE STEM CELL AND METHOD FOR INDUCING THE DIFFERENTIATION OF THE EMBRYONAL STEM CELL |
| DE102006054041B3 (de) | 2006-11-16 | 2008-05-08 | Pierburg Gmbh | Regelvorrichtung für eine Verbrennungskraftmaschine |
| KR20100014504A (ko) | 2007-02-23 | 2010-02-10 | 어드밴스드 셀 테크놀로지, 인코포레이티드 | 분화된 세포를 리프로그래밍하고, 리프로그래밍된 세포로부터 동물 및 배아 줄기세포를 생성시키기 위한 고도로 효율적인 방법 |
| ES2507507T3 (es) | 2007-05-24 | 2014-10-15 | Apceth Gmbh & Co. Kg | Células madre mesenquimales CD34 negativas modificadas genéticamente para el tratamiento de tumores |
| WO2008151386A1 (en) | 2007-06-15 | 2008-12-18 | Australian Stem Cell Centre Ltd | Megakaryocyte differentiation |
| JP2008307007A (ja) | 2007-06-15 | 2008-12-25 | Bayer Schering Pharma Ag | 出生後のヒト組織由来未分化幹細胞から誘導したヒト多能性幹細胞 |
| US9095562B2 (en) | 2007-07-05 | 2015-08-04 | Regenerative Sciences, Inc. | Methods and compositions for optimized expansion and implantation of mesenchymal stem cells |
| CN103169731A (zh) | 2007-08-06 | 2013-06-26 | 成血管细胞系统公司 | 用于体内生成、修复和/或维护结缔组织的方法 |
| KR101039235B1 (ko) * | 2007-08-29 | 2011-06-07 | 메디포스트(주) | 제대혈 유래 간엽줄기세포를 포함하는 인터루킨-8 또는지알오-알파 발현 세포가 관련된 질병의 진단, 예방 또는치료용 조성물 |
| US7615374B2 (en) | 2007-09-25 | 2009-11-10 | Wisconsin Alumni Research Foundation | Generation of clonal mesenchymal progenitors and mesenchymal stem cell lines under serum-free conditions |
| US20110236971A2 (en) | 2007-09-25 | 2011-09-29 | Maksym Vodyanyk | Generation of Clonal Mesenchymal Progenitors and Mesenchymal Stem Cell Lines Under Serum-Free Conditions |
| EP2203176B1 (en) | 2007-09-28 | 2014-11-26 | Anthrogenesis Corporation | Tumor suppression using human placental perfusate and human placenta-derived intermediate natural killer cells |
| EP2209888B1 (en) | 2007-10-12 | 2019-12-04 | Astellas Institute for Regenerative Medicine | Improved methods of producing rpe cells and compositions of rpe cells |
| US20100304480A1 (en) | 2007-10-19 | 2010-12-02 | Goodell Margaret A | Hematopoietic Fingerprints: Methods of Use |
| US9683232B2 (en) | 2007-12-10 | 2017-06-20 | Kyoto University | Efficient method for nuclear reprogramming |
| US10046011B2 (en) | 2008-01-31 | 2018-08-14 | Rutgers, The State University Of New Jersey | Compositions for inducing or suppressing an immune response |
| US8685728B2 (en) | 2008-01-31 | 2014-04-01 | Rutgers The State University Of New Jersey | Kit containing stem cells and cytokines for use in attenuating immune responses |
| BRPI0905715A2 (pt) | 2008-02-15 | 2015-07-14 | Bone Therapeutics | Composição farmacêutica e kit de componentes |
| WO2009104825A1 (en) | 2008-02-18 | 2009-08-27 | Kaist | Method for inducing the defferentiation of embryonic stem cells into hemangioblast |
| US20110086424A1 (en) | 2008-05-06 | 2011-04-14 | Advanced Cell Technology, Inc. | Methods for producing enucleated erythroid cells derived from pluripotent stem cells |
| BRPI0912201A2 (pt) | 2008-05-06 | 2019-09-24 | Advanced Cell Tech Inc | células formadoras de colônias de hemangios e células de hemangio não enxertantes |
| KR20160065213A (ko) | 2008-05-07 | 2016-06-08 | 본 테라퓨틱스 소시에테아노님 | 간엽 줄기 세포 및 골-형성 세포 |
| WO2010017216A2 (en) * | 2008-08-04 | 2010-02-11 | Allocure | Mesenchymal stromal cell populations and methods of isolating and using same |
| SG193888A1 (en) | 2008-09-03 | 2013-10-30 | Mesoblast Inc | Expansion of haemopoietic precursors |
| FR2938947B1 (fr) | 2008-11-25 | 2012-08-17 | A Volute | Procede de traitement du signal, notamment audionumerique. |
| EP2221362A1 (en) | 2009-02-19 | 2010-08-25 | Naturin GmbH & Co | Method for the cryopreservation of cells, artificial cell constructs or three-dimensional complex tissues assemblies |
| CA2753679C (en) | 2009-02-27 | 2021-03-02 | Cellular Dynamics International, Inc. | Differentiation of pluripotent cells |
| CA2756670A1 (en) | 2009-03-26 | 2010-09-30 | The Regents Of The University Of California | Mesenchymal stem cells producing inhibitory rna for disease modification |
| JP2010252778A (ja) * | 2009-04-02 | 2010-11-11 | Shizui Bank Kk | 歯髄由来間葉系幹細胞の分離方法及び分離した幹細胞並びにそれらを用いた肝細胞系譜への分化 |
| HUE031921T2 (en) | 2009-07-09 | 2017-08-28 | Tigenix S A U | Methods and preparations for use in cell therapy |
| EP2485741A4 (en) * | 2009-10-06 | 2013-07-24 | Cohen Mcniece Foundation | PREPARATION AND USE OF STROMAL CELLS FOR THE TREATMENT OF CARDIAC DISORDERS |
| WO2011047345A2 (en) | 2009-10-15 | 2011-04-21 | Tai June Yoo | Methods of treating diseases of conditions using mesenchymal stem cells |
| WO2011053860A2 (en) * | 2009-10-30 | 2011-05-05 | Allocure, Inc. | Mesenchymal stromal cell populations and methods of using same |
| IL281453B (en) | 2009-11-17 | 2022-07-01 | Astellas Inst For Regenerative Medicine | Methods for preparing human rpe cells and pharmaceutical preparations of human rpe cells |
| US8900860B2 (en) * | 2009-11-30 | 2014-12-02 | National Yang-Ming University | Method for expanding mesenchymal stem cells in low-density and hypoxic culture |
| BR112012014104A2 (pt) | 2009-12-04 | 2016-07-05 | Stem Cell & Regenerative Medicine International Inc | método de geração de células destrutoras naturais e células dendríticas de hemangioblastos embrionários humanos derivados de células-tronco |
| KR20120128605A (ko) | 2009-12-04 | 2012-11-27 | 스템 셀 앤드 리제너러티브 메디신 인터내셔날, 인크. | 기질 없는 조건 하에서 인간 배아줄기세포로부터 기능적 거핵구 및 혈소판의 대규모 생성 |
| US20120294837A1 (en) * | 2010-02-02 | 2012-11-22 | University Of Rochester | Methods of isolating and culturing mesenchymal stem cells |
| EP2363136A1 (en) * | 2010-03-02 | 2011-09-07 | Fresenius Medical Care Deutschland GmbH | Microvesicles (MVs) derived from adult stem cells for use in the therapeutic treatment of a tumor disease |
| DK2545928T3 (en) | 2010-03-10 | 2016-10-03 | Two Cells Co Ltd | CELL PREPARATION CONTAINING MESENYKYMAL STEM CELLS AND METHOD OF PRODUCING THEREOF |
| WO2011124741A1 (es) | 2010-04-08 | 2011-10-13 | Fundación Progreso Y Salud | Uso de un medio de cultivo condicionado por células madre mesenquimales para la diferenciación de células madre pluripotentes humanas |
| KR101330327B1 (ko) | 2010-05-07 | 2013-11-14 | 한국생명공학연구원 | 줄기세포로부터 생성된 배아체를 대량 증식 및 유지하는 방법 |
| PL2620156T3 (pl) | 2010-08-23 | 2019-10-31 | Kang Stem Biotech Co Ltd | Kompozycja farmaceutyczna do zapobiegania lub leczenia chorób immunologicznych lub chorób zapalnych, zawierająca komórki macierzyste traktowane agonistą NOD2 lub jego produktem hodowlanym |
| WO2012048093A2 (en) * | 2010-10-08 | 2012-04-12 | Osiris Therapeutics, Inc. | Enhanced msc preparations |
| KR20120095022A (ko) | 2011-02-18 | 2012-08-28 | 가톨릭대학교 산학협력단 | 간엽줄기세포 및 면역조절 t 세포를 유효성분으로 포함하는 이식편대숙주질환 예방 또는 치료용 세포치료제 조성물 |
| PL2785359T3 (pl) | 2011-11-30 | 2018-12-31 | Astellas Institute For Regenerative Medicine | Mezenchymalne komórki zrębowe i związane z nimi zastosowania |
| US8961956B2 (en) | 2011-11-30 | 2015-02-24 | Ocata Therapeutics, Inc. | Mesenchymal stromal cells and uses related thereto |
| KR101477016B1 (ko) | 2012-01-19 | 2014-12-29 | (주)차바이오텍 | 인간 배아줄기세포 유래 혈관주위 전구세포의 제조방법 및 이를 포함하는 세포치료 조성물 |
| CN104471059B (zh) | 2012-07-12 | 2018-04-17 | 珠海横琴爱姆斯坦生物科技有限公司 | 人胚胎干细胞衍生的间充质样干细胞、方法及其应用 |
| JP6377632B2 (ja) | 2012-12-14 | 2018-08-22 | ラトガース,ザ ステート ユニバーシティ オブ ニュー ジャージー | 幹細胞の免疫制御作用を調節する方法 |
| ES2647494T3 (es) | 2013-03-01 | 2017-12-21 | Apceth Gmbh & Co. Kg | Protección del endotelio vascular de las reacciones citotóxicas mediadas inmunológicamente con células progenitoras humanas cd34-negativo |
| KR101669124B1 (ko) | 2013-07-11 | 2016-10-25 | 서울대학교병원 | 인간 배아줄기세포에서 유래된 중간엽 줄기세포를 유효성분으로 함유하는 간섬유화 또는 간경화 예방 및 치료용 조성물 |
| KR20160073382A (ko) | 2013-10-04 | 2016-06-24 | 셀 아이디어스 피티와이 엘티디 | 세포 치료를 위한 바이오마커들 |
| EP3107995B1 (en) | 2014-02-18 | 2019-10-30 | Massachusetts Institute Of Technology | Biophysically sorted osteoprogenitors from culture expanded bone marrow derived mesenchymal stromal cells (mscs) |
| WO2015189063A1 (en) | 2014-06-10 | 2015-12-17 | Mesoblast International Sàrl | Treatment of immune disorders |
| JP6459257B2 (ja) | 2014-07-08 | 2019-01-30 | 富士ゼロックス株式会社 | 画像形成装置 |
| WO2016018761A1 (en) | 2014-07-28 | 2016-02-04 | The Texas A&M University System | Mesenchymal stem cells expressing biomarkers that predict the effectiveness of the mesenchymal stem cells for treating diseases and disorders |
| JP6998768B2 (ja) | 2015-08-28 | 2022-02-10 | ロート製薬株式会社 | Ror1陽性の間葉系幹細胞及びその調製方法、ror1陽性の間葉系幹細胞を含む医薬組成物及びその調製方法、並びにror1陽性の間葉系幹細胞を用いる疾患の予防又は治療方法 |
| CN109312302A (zh) | 2015-10-27 | 2019-02-05 | 株式会社钟化 | 包含间充质系干细胞的细胞群的制造方法、间充质系干细胞、细胞群、以及医药组合物 |
| EP3385368B1 (en) | 2015-12-03 | 2023-03-01 | Takara Bio Inc. | Method for producing mesenchymal stem cells |
| KR102388828B1 (ko) | 2016-03-16 | 2022-04-21 | 시나타 세라퓨틱스 엘티디 | 콜로니 형성 배지 및 그 용도 |
| CN109104869B (zh) | 2016-04-27 | 2022-07-01 | 日本乐敦制药株式会社 | 表达细胞表面标记物的间充质干细胞、包含该间充质干细胞的药物组合物及其制备方法 |
| KR101816246B1 (ko) | 2016-09-07 | 2018-01-08 | 에스씨엠생명과학 주식회사 | 염증 자극된 중간엽 줄기세포를 포함하는 면역질환 또는 염증 질환의 예방 또는 치료용 약학적 조성물 |
| JP2019534015A (ja) | 2016-10-27 | 2019-11-28 | ザ・トラスティーズ・オブ・コロンビア・ユニバーシティ・イン・ザ・シティ・オブ・ニューヨーク | 免疫抑制間葉系細胞及びその形成方法 |
| CN110352240A (zh) | 2016-12-12 | 2019-10-18 | 北京汉氏联合生物技术股份有限公司 | 围产期组织衍生的间充质干细胞:其制备方法和用途 |
| CN110494556B (zh) | 2017-04-03 | 2024-04-30 | 株式会社钟化 | 包含间充质系干细胞的细胞群、其制造方法、以及医药组合物 |
| US20200056156A1 (en) | 2017-04-03 | 2020-02-20 | Kaneka Corporation | Cell population comprising mesenchymal stem cells, method for producing the same, and pharmaceutical composition |
| EP3619294A1 (en) | 2017-05-04 | 2020-03-11 | Mesoblast International Sàrl | Mesenchymal lineage precursor or stem cells with enhanced immunosuppression |
-
2012
- 2012-11-30 PL PL12854438T patent/PL2785359T3/pl unknown
- 2012-11-30 SI SI201231414T patent/SI2785359T1/sl unknown
- 2012-11-30 LT LTEP12854438.4T patent/LT2785359T/lt unknown
- 2012-11-30 JP JP2014544956A patent/JP2015500810A/ja active Pending
- 2012-11-30 KR KR1020237013378A patent/KR102811933B1/ko active Active
- 2012-11-30 HU HUE12854438A patent/HUE040566T2/hu unknown
- 2012-11-30 WO PCT/US2012/067464 patent/WO2013082543A1/en not_active Ceased
- 2012-11-30 TW TW109121434A patent/TWI812867B/zh active
- 2012-11-30 DK DK12854438.4T patent/DK2785359T3/en active
- 2012-11-30 ES ES12854438T patent/ES2690212T3/es active Active
- 2012-11-30 KR KR1020207012502A patent/KR102246369B1/ko active Active
- 2012-11-30 TW TW112104480A patent/TWI921638B/zh active
- 2012-11-30 AU AU2012345630A patent/AU2012345630A1/en not_active Abandoned
- 2012-11-30 CN CN201810244786.XA patent/CN108478599B/zh active Active
- 2012-11-30 TW TW113148445A patent/TW202537630A/zh unknown
- 2012-11-30 PT PT12854438T patent/PT2785359T/pt unknown
- 2012-11-30 KR KR1020147017312A patent/KR102108245B1/ko active Active
- 2012-11-30 TW TW101145218A patent/TWI698527B/zh active
- 2012-11-30 US US13/691,349 patent/US8962321B2/en active Active
- 2012-11-30 EP EP18186151.9A patent/EP3449929B1/en active Active
- 2012-11-30 RS RS20181203A patent/RS57886B1/sr unknown
- 2012-11-30 CA CA2857545A patent/CA2857545A1/en active Pending
- 2012-11-30 HR HRP20181515TT patent/HRP20181515T1/hr unknown
- 2012-11-30 CN CN201280067692.0A patent/CN104136034B/zh active Active
- 2012-11-30 KR KR1020217010975A patent/KR102525175B1/ko active Active
- 2012-11-30 EP EP12854438.4A patent/EP2785359B1/en active Active
- 2012-11-30 TW TW106124778A patent/TWI698242B/zh active
-
2014
- 2014-10-01 US US14/504,351 patent/US20160038543A1/en not_active Abandoned
-
2017
- 2017-03-23 US US15/467,201 patent/US20170252374A1/en not_active Abandoned
- 2017-09-08 JP JP2017172589A patent/JP6526130B2/ja active Active
- 2017-10-04 AU AU2017239526A patent/AU2017239526B2/en active Active
-
2018
- 2018-10-25 CY CY20181101104T patent/CY1122275T1/el unknown
-
2019
- 2019-05-07 JP JP2019087857A patent/JP6983195B2/ja active Active
- 2019-11-14 AU AU2019264631A patent/AU2019264631B2/en active Active
-
2020
- 2020-09-16 US US17/022,807 patent/US12097223B2/en active Active
-
2021
- 2021-11-22 JP JP2021189684A patent/JP7777430B2/ja active Active
-
2022
- 2022-04-20 AU AU2022202639A patent/AU2022202639B2/en active Active
-
2023
- 2023-12-14 JP JP2023211105A patent/JP2024067032A/ja active Pending
-
2024
- 2024-08-21 US US18/811,109 patent/US20250090590A1/en active Pending
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK2837680T3 (da) | Mammaliacellekultur | |
| DK2775557T3 (da) | Brændselscelle | |
| EP2664017A4 (en) | STACK OF FLOW CELLS | |
| HRP20182098T1 (hr) | Anti-angptl3 antitijela i njihove primjene | |
| DK3442233T3 (da) | Nedarvning i samplearraymultitræsunderinddeling | |
| DK2552261T3 (da) | Propfilter med proprum med aromakugle | |
| DK3421470T3 (da) | Substituerede 5-fluor-1h-pyrazolopyridiner i krytallinsk form | |
| DK3415157T3 (da) | N-acyldipeptidderivater og anvendelser deraf | |
| HRP20181152T1 (hr) | Progenitorne stanice mezodermalnog porijekla | |
| EP2557610A4 (en) | Cell module | |
| EP3719852C0 (en) | SOLAR CELL | |
| HRP20160922T1 (hr) | Oligopeptidni spojevi i njihove uporabe | |
| EP3701800C0 (en) | Use | |
| DK2704744T3 (da) | Komplementfaktor-b-analoger og anvendelser deraf | |
| DK2683643T3 (da) | Prostatacancercellelinjer, gensignaturer og anvendelser deraf | |
| DK2912165T3 (da) | Nyrecellepopulationer og anvendelser deraf | |
| EP2535261A4 (en) | SCHAUFELRADJACHT | |
| BR112013007852A2 (pt) | pilha reforçada aperfeiçoada | |
| IL235125A0 (en) | Microbial fuel cell | |
| EP2610945A4 (en) | STACK CELL | |
| EP2654170A4 (en) | CHARGER | |
| EP2831949A4 (en) | SODIUM OXYGEN CELLS | |
| DK2753346T3 (da) | Ceramidase og celledifferentiering | |
| EP2613418A4 (en) | CHARGER | |
| EP2757623A4 (en) | FUEL CELL |