AR047712A1 - Metodo de tratamiento de una lesion de tejido esqueletico blando natural administrando una composicion de celulas madre mesenquimatosas - Google Patents
Metodo de tratamiento de una lesion de tejido esqueletico blando natural administrando una composicion de celulas madre mesenquimatosasInfo
- Publication number
- AR047712A1 AR047712A1 ARP030103236A ARP030103236A AR047712A1 AR 047712 A1 AR047712 A1 AR 047712A1 AR P030103236 A ARP030103236 A AR P030103236A AR P030103236 A ARP030103236 A AR P030103236A AR 047712 A1 AR047712 A1 AR 047712A1
- Authority
- AR
- Argentina
- Prior art keywords
- composition
- skelettic
- mesenquimatose
- managing
- treatment method
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/33—Fibroblasts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/32—Bones; Osteocytes; Osteoblasts; Tendons; Tenocytes; Teeth; Odontoblasts; Cartilage; Chondrocytes; Synovial membrane
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/16—Blood plasma; Blood serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/19—Platelets; Megacaryocytes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/48—Reproductive organs
- A61K35/51—Umbilical cord; Umbilical cord blood; Umbilical stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
Abstract
Un método para el tratamiento de una lesion de tejido esquelético blando natural en un paciente, donde dicho método comprende administrar al paciente una composicion de células madre mesenquimatosas en una suspension líquida enriquecida, comparada con la fuente natural de dichas células, o tenocitos derivados de las mismas. El método es particularmente adecuado para la regeneracion de tendones en mamíferos de competicion, tales como el tendon flexor digital superficial del caballo. El uso de dicha composicion.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0220841A GB0220841D0 (en) | 2002-09-07 | 2002-09-07 | Therapy |
GB0226275A GB0226275D0 (en) | 2002-11-12 | 2002-11-12 | Method of treatment |
Publications (1)
Publication Number | Publication Date |
---|---|
AR047712A1 true AR047712A1 (es) | 2006-02-15 |
Family
ID=31980022
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP030103236A AR047712A1 (es) | 2002-09-07 | 2003-09-05 | Metodo de tratamiento de una lesion de tejido esqueletico blando natural administrando una composicion de celulas madre mesenquimatosas |
Country Status (10)
Country | Link |
---|---|
US (5) | US8178084B2 (es) |
EP (3) | EP1545567B1 (es) |
AR (1) | AR047712A1 (es) |
AT (2) | ATE389412T1 (es) |
AU (1) | AU2003263340B2 (es) |
CA (1) | CA2538187C (es) |
DE (2) | DE60319848T2 (es) |
ES (1) | ES2304541T3 (es) |
NZ (1) | NZ539308A (es) |
WO (1) | WO2004022078A1 (es) |
Families Citing this family (43)
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US7608258B2 (en) | 2002-04-13 | 2009-10-27 | Allan Mishra | Method for treatment of tendinosis using platelet rich plasma |
US6811777B2 (en) | 2002-04-13 | 2004-11-02 | Allan Mishra | Compositions and minimally invasive methods for treating incomplete connective tissue repair |
US7429378B2 (en) | 2003-05-13 | 2008-09-30 | Depuy Spine, Inc. | Transdiscal administration of high affinity anti-MMP inhibitors |
AU2004291065B2 (en) * | 2003-05-13 | 2007-11-01 | Depuy Spine, Inc. | Autologous treatment of degenerated disc with cells |
US8273347B2 (en) | 2003-05-13 | 2012-09-25 | Depuy Spine, Inc. | Autologous treatment of degenerated disc with cells |
US7344716B2 (en) | 2003-05-13 | 2008-03-18 | Depuy Spine, Inc. | Transdiscal administration of specific inhibitors of pro-inflammatory cytokines |
US7553827B2 (en) | 2003-08-13 | 2009-06-30 | Depuy Spine, Inc. | Transdiscal administration of cycline compounds |
US8361467B2 (en) | 2003-07-30 | 2013-01-29 | Depuy Spine, Inc. | Trans-capsular administration of high specificity cytokine inhibitors into orthopedic joints |
WO2005035742A2 (en) | 2003-10-08 | 2005-04-21 | Vet-Stem Inc. | Methods of preparing and using stem cell compositions and kits comprising the same |
US8895540B2 (en) | 2003-11-26 | 2014-11-25 | DePuy Synthes Products, LLC | Local intraosseous administration of bone forming agents and anti-resorptive agents, and devices therefor |
WO2005065242A2 (en) | 2003-12-29 | 2005-07-21 | Am Biosolutions | Method of treating cancer using platelet releasate |
US7462268B2 (en) | 2004-08-20 | 2008-12-09 | Allan Mishra | Particle/cell separation device and compositions |
KR100593397B1 (ko) * | 2004-10-27 | 2006-06-28 | 한국원자력연구소 | 중배엽 줄기세포 및/또는 p 물질을 함유하는 상처 치유또는 상처 치유 촉진제, 또는 세포 치료제 |
ES2671873T3 (es) | 2007-04-24 | 2018-06-11 | Orthocell Limited | Bioestructuras que contienen tenocitos y tratamiento utilizando las mismas |
US8785191B2 (en) * | 2007-08-27 | 2014-07-22 | University Of Connecticut | Concentration of stem cells obtained during orthopaedic surgeries |
WO2009074807A2 (en) | 2007-12-12 | 2009-06-18 | Imperial Innovations Limited | Methods |
US8986696B2 (en) | 2007-12-21 | 2015-03-24 | Depuy Mitek, Inc. | Trans-capsular administration of p38 map kinase inhibitors into orthopedic joints |
IT1394262B1 (it) * | 2008-07-17 | 2012-06-01 | Università Degli Studi Di Milano | Metodo per la produzione in vitro di tenociti a partire da cellule staminali mesenchimali, nonché rispettivi metodi per la caratterizzazione di detti tenociti e di dette cellule staminali mesenchimali |
US20100112081A1 (en) | 2008-10-07 | 2010-05-06 | Bioparadox, Llc | Use of platelet rich plasma composition in the treatment of cardiac conduction abnormalities |
GB0820492D0 (en) * | 2008-11-07 | 2008-12-17 | Sportcell | Cell compositions and uses thereof |
WO2010140162A2 (en) * | 2009-05-17 | 2010-12-09 | Dravida Subhadra | A process for preparing stem cell based formulations |
DE102010046218A1 (de) | 2010-09-21 | 2012-03-22 | Livlmplant Gmbh | Zell-basiertes Injektionssystem zur Behandlung von Verletzungen |
EP3141599B1 (en) * | 2011-03-18 | 2022-12-21 | MicroVascular Tissues, Inc. | Allogeneic microvascular tissue for soft tissue treatments |
CN104471059B (zh) | 2012-07-12 | 2018-04-17 | 珠海横琴爱姆斯坦生物科技有限公司 | 人胚胎干细胞衍生的间充质样干细胞、方法及其应用 |
US11819522B2 (en) | 2012-09-19 | 2023-11-21 | Microvascular Tissues, Inc. | Compositions and methods for treating and preventing tissue injury and disease |
WO2014047067A1 (en) | 2012-09-19 | 2014-03-27 | Tornier, Inc. | Compositions and methods for treating and preventing tissue injury and disease |
US9872937B2 (en) | 2012-09-19 | 2018-01-23 | Microvascular Tissues, Inc. | Compositions and methods for treating and preventing tissue injury and disease |
US10596202B2 (en) | 2012-09-19 | 2020-03-24 | Microvascular Tissues, Inc. | Compositions and methods for treating and preventing tissue injury and disease |
WO2014167142A1 (es) | 2013-04-09 | 2014-10-16 | Equicord, S.L. | Procedimiento para el tratamiento de células madre mesenquimales equinas y sistema para llevar a cabo el procedimiento |
US20140356893A1 (en) | 2013-06-04 | 2014-12-04 | Allan Mishra | Compositions and methods for using platelet-rich plasma for drug discovery, cell nuclear reprogramming, proliferation or differentiation |
EP3083944B1 (en) * | 2013-12-19 | 2020-12-09 | Université de Liège | Mammalian muscle-derived stem cells |
WO2016015007A1 (en) | 2014-07-25 | 2016-01-28 | Recellerate, Inc. | Methods of treating exercise-induced pulmonary hemorrhage |
WO2016073989A2 (en) * | 2014-11-07 | 2016-05-12 | The Trustees Of Columbia University In The City Of New York | Osteochondroreticular stem cells for bone and cartilage regeneration |
RU2644650C2 (ru) | 2014-12-01 | 2018-02-13 | Общество с ограниченной ответственностью "Т-Хелпер Клеточные Технологии" | Материал стволовых клеток и способ его получения |
WO2016172004A1 (en) * | 2015-04-18 | 2016-10-27 | The Johns Hopkins University | Bone healing, angiogenesis-promoting and vasculogenesis-producing system |
WO2017059089A1 (en) * | 2015-09-29 | 2017-04-06 | Anicell Biotech, Llc | Methods and articles of manufacture for the treatment of animals |
US9861410B2 (en) | 2016-05-06 | 2018-01-09 | Medos International Sarl | Methods, devices, and systems for blood flow |
RU2708329C2 (ru) | 2016-05-31 | 2019-12-05 | Общество с ограниченной ответственностью "Т-Хелпер Клеточные Технологии" | Материал стволовых клеток, композиции и способы применения |
CN106308817B (zh) * | 2016-08-12 | 2023-07-28 | 玉溪九洲生物技术有限责任公司 | 一种马血浆采集系统 |
FR3058065B1 (fr) * | 2016-10-27 | 2019-02-01 | Scarcell Therapeutics | Composition pour le traitement d’une affection de l’appareil locomoteur |
EP3388511A1 (en) * | 2017-04-12 | 2018-10-17 | Revatis SA | New uses of mammalian muscle derived stel cells |
WO2021041858A1 (en) * | 2019-08-29 | 2021-03-04 | Icahn School Of Medicine At Mount Sinai | Differentiated tendon cells derived from pluripotent progenitor cells and methods of use thereof |
RU2722162C1 (ru) * | 2019-10-14 | 2020-05-27 | Федеральное государственное бюджетное учреждение науки Сибирский федеральный научный центр агробиотехнологий Российской академии наук (СФНЦА РАН) | Способ лечения травм сухожильно-связочного аппарата у лошадей |
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US5811094A (en) * | 1990-11-16 | 1998-09-22 | Osiris Therapeutics, Inc. | Connective tissue regeneration using human mesenchymal stem cell preparations |
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DE69937888T2 (de) * | 1998-07-31 | 2009-01-02 | Genzyme Corp., Cambridge | Verfahren zur Herstellung mesenchymaler Stammzellen |
AU2998300A (en) | 1999-02-17 | 2000-09-04 | United States Surgical Corporation | Genetically altered mesenchymal stem cells and methods of use thereof |
FR2799371A1 (fr) * | 1999-10-12 | 2001-04-13 | Univ Paris Curie | Compositions de tenocytes preparation et utilisations |
EP1099754A1 (en) | 1999-11-10 | 2001-05-16 | Universiteit Leiden | Mesenchymal stem cells and/or progenitor cells, their isolation and use |
EP2283880A3 (en) * | 2000-03-20 | 2014-07-09 | Biosphere Medical, Inc. | Injectable microspheres for tissue construction |
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US20020045260A1 (en) * | 2000-10-17 | 2002-04-18 | Shih-Chieh Hung | Method of isolating mesenchymal stem cells |
AU2002224444A1 (en) * | 2000-10-24 | 2002-05-06 | Children's Hospital Of Philadelphia | Therapeutic uses for mesenchymal stromal cells |
JP4959916B2 (ja) | 2001-08-14 | 2012-06-27 | メディポスト・カンパニー・リミテッド | 関節軟骨損傷治療用組成物 |
US6811777B2 (en) * | 2002-04-13 | 2004-11-02 | Allan Mishra | Compositions and minimally invasive methods for treating incomplete connective tissue repair |
-
2003
- 2003-09-05 AR ARP030103236A patent/AR047712A1/es not_active Application Discontinuation
- 2003-09-08 EP EP03793917A patent/EP1545567B1/en not_active Expired - Lifetime
- 2003-09-08 AU AU2003263340A patent/AU2003263340B2/en not_active Ceased
- 2003-09-08 DE DE60319848T patent/DE60319848T2/de not_active Expired - Lifetime
- 2003-09-08 DE DE60335752T patent/DE60335752D1/de not_active Expired - Lifetime
- 2003-09-08 US US10/526,753 patent/US8178084B2/en active Active - Reinstated
- 2003-09-08 EP EP07014066A patent/EP1872789B1/en not_active Expired - Lifetime
- 2003-09-08 ES ES03793917T patent/ES2304541T3/es not_active Expired - Lifetime
- 2003-09-08 WO PCT/GB2003/003894 patent/WO2004022078A1/en active IP Right Grant
- 2003-09-08 EP EP10186184A patent/EP2316462A1/en not_active Withdrawn
- 2003-09-08 CA CA2538187A patent/CA2538187C/en not_active Expired - Fee Related
- 2003-09-08 AT AT03793917T patent/ATE389412T1/de active
- 2003-09-08 AT AT07014066T patent/ATE494898T1/de not_active IP Right Cessation
- 2003-09-08 NZ NZ539308A patent/NZ539308A/en not_active IP Right Cessation
-
2012
- 2012-05-15 US US13/471,517 patent/US20120230960A1/en not_active Abandoned
- 2012-07-17 US US13/551,051 patent/US20130039896A1/en not_active Abandoned
-
2014
- 2014-09-16 US US14/487,660 patent/US20150017145A1/en not_active Abandoned
-
2017
- 2017-02-24 US US15/442,590 patent/US20170258848A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
AU2003263340B2 (en) | 2008-12-18 |
US20060130852A1 (en) | 2006-06-22 |
ATE494898T1 (de) | 2011-01-15 |
DE60319848D1 (de) | 2008-04-30 |
DE60319848T2 (de) | 2009-04-30 |
US8178084B2 (en) | 2012-05-15 |
EP1872789B1 (en) | 2011-01-12 |
AU2003263340A1 (en) | 2004-03-29 |
DE60335752D1 (es) | 2011-02-24 |
CA2538187A1 (en) | 2004-03-18 |
NZ539308A (en) | 2008-03-28 |
CA2538187C (en) | 2019-01-08 |
WO2004022078A1 (en) | 2004-03-18 |
US20130039896A1 (en) | 2013-02-14 |
EP2316462A1 (en) | 2011-05-04 |
EP1545567A1 (en) | 2005-06-29 |
ES2304541T3 (es) | 2008-10-16 |
US20150017145A1 (en) | 2015-01-15 |
US20120230960A1 (en) | 2012-09-13 |
EP1545567B1 (en) | 2008-03-19 |
ATE389412T1 (de) | 2008-04-15 |
US20170258848A1 (en) | 2017-09-14 |
EP1872789A1 (en) | 2008-01-02 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA | Abandonment or withdrawal |