DE60319848D1 - Medikament mit mesenchym-stammzellen - Google Patents

Medikament mit mesenchym-stammzellen

Info

Publication number
DE60319848D1
DE60319848D1 DE60319848T DE60319848T DE60319848D1 DE 60319848 D1 DE60319848 D1 DE 60319848D1 DE 60319848 T DE60319848 T DE 60319848T DE 60319848 T DE60319848 T DE 60319848T DE 60319848 D1 DE60319848 D1 DE 60319848D1
Authority
DE
Germany
Prior art keywords
mesenchym
medicament
stem cells
stem
cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60319848T
Other languages
English (en)
Other versions
DE60319848T2 (de
Inventor
Roger Kenneth Smith
Kenneth Gregory Mcgarrell
Allen Edward Goodship
Gordon William Blunn
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Quy Biosciences Ltd Norwich Norfolk Gb
Original Assignee
MEDCELL BIOSCIENCE Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0220841A external-priority patent/GB0220841D0/en
Priority claimed from GB0226275A external-priority patent/GB0226275D0/en
Application filed by MEDCELL BIOSCIENCE Ltd filed Critical MEDCELL BIOSCIENCE Ltd
Application granted granted Critical
Publication of DE60319848D1 publication Critical patent/DE60319848D1/de
Publication of DE60319848T2 publication Critical patent/DE60319848T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/33—Fibroblasts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/32—Bones; Osteocytes; Osteoblasts; Tendons; Tenocytes; Teeth; Odontoblasts; Cartilage; Chondrocytes; Synovial membrane
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/16—Blood plasma; Blood serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/19—Platelets; Megacaryocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/48—Reproductive organs
    • A61K35/51—Umbilical cord; Umbilical cord blood; Umbilical stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
DE60319848T 2002-09-07 2003-09-08 Medikament mit Mesenchymstammzellen Expired - Lifetime DE60319848T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB0220841A GB0220841D0 (en) 2002-09-07 2002-09-07 Therapy
GB0220841 2002-09-07
GB0226275 2002-11-12
GB0226275A GB0226275D0 (en) 2002-11-12 2002-11-12 Method of treatment
PCT/GB2003/003894 WO2004022078A1 (en) 2002-09-07 2003-09-08 Pharmaceutical kits comprising mesenchymal stem cells

Publications (2)

Publication Number Publication Date
DE60319848D1 true DE60319848D1 (de) 2008-04-30
DE60319848T2 DE60319848T2 (de) 2009-04-30

Family

ID=31980022

Family Applications (2)

Application Number Title Priority Date Filing Date
DE60319848T Expired - Lifetime DE60319848T2 (de) 2002-09-07 2003-09-08 Medikament mit Mesenchymstammzellen
DE60335752T Expired - Lifetime DE60335752D1 (de) 2002-09-07 2003-09-08

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE60335752T Expired - Lifetime DE60335752D1 (de) 2002-09-07 2003-09-08

Country Status (10)

Country Link
US (5) US8178084B2 (de)
EP (3) EP1872789B1 (de)
AR (1) AR047712A1 (de)
AT (2) ATE494898T1 (de)
AU (1) AU2003263340B2 (de)
CA (1) CA2538187C (de)
DE (2) DE60319848T2 (de)
ES (1) ES2304541T3 (de)
NZ (1) NZ539308A (de)
WO (1) WO2004022078A1 (de)

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US7608258B2 (en) 2002-04-13 2009-10-27 Allan Mishra Method for treatment of tendinosis using platelet rich plasma
US6811777B2 (en) 2002-04-13 2004-11-02 Allan Mishra Compositions and minimally invasive methods for treating incomplete connective tissue repair
AU2004291065B2 (en) * 2003-05-13 2007-11-01 Depuy Spine, Inc. Autologous treatment of degenerated disc with cells
US7429378B2 (en) 2003-05-13 2008-09-30 Depuy Spine, Inc. Transdiscal administration of high affinity anti-MMP inhibitors
US7553827B2 (en) 2003-08-13 2009-06-30 Depuy Spine, Inc. Transdiscal administration of cycline compounds
US7344716B2 (en) 2003-05-13 2008-03-18 Depuy Spine, Inc. Transdiscal administration of specific inhibitors of pro-inflammatory cytokines
US8273347B2 (en) 2003-05-13 2012-09-25 Depuy Spine, Inc. Autologous treatment of degenerated disc with cells
US8361467B2 (en) 2003-07-30 2013-01-29 Depuy Spine, Inc. Trans-capsular administration of high specificity cytokine inhibitors into orthopedic joints
NZ597965A (en) 2003-10-08 2013-09-27 Vet Stem Inc Methods of preparing and using stem cell compositions and kits comprising the same
US8895540B2 (en) 2003-11-26 2014-11-25 DePuy Synthes Products, LLC Local intraosseous administration of bone forming agents and anti-resorptive agents, and devices therefor
WO2005065242A2 (en) 2003-12-29 2005-07-21 Am Biosolutions Method of treating cancer using platelet releasate
US7462268B2 (en) 2004-08-20 2008-12-09 Allan Mishra Particle/cell separation device and compositions
KR100593397B1 (ko) 2004-10-27 2006-06-28 한국원자력연구소 중배엽 줄기세포 및/또는 ｐ 물질을 함유하는 상처 치유또는 상처 치유 촉진제, 또는 세포 치료제
EP2150281B1 (de) 2007-04-24 2018-04-11 Orthocell Limited Tenozyten-enthaltende biologische gerüste und behandlung damit
US8785191B2 (en) * 2007-08-27 2014-07-22 University Of Connecticut Concentration of stem cells obtained during orthopaedic surgeries
WO2009074807A2 (en) 2007-12-12 2009-06-18 Imperial Innovations Limited Methods
US8986696B2 (en) 2007-12-21 2015-03-24 Depuy Mitek, Inc. Trans-capsular administration of p38 map kinase inhibitors into orthopedic joints
IT1394262B1 (it) * 2008-07-17 2012-06-01 Università Degli Studi Di Milano Metodo per la produzione in vitro di tenociti a partire da cellule staminali mesenchimali, nonché rispettivi metodi per la caratterizzazione di detti tenociti e di dette cellule staminali mesenchimali
WO2010042658A1 (en) 2008-10-07 2010-04-15 Bioparadox, Llc Use of platelet rich plasma composition in the treatment of cardiac conduction abnormalities
GB0820492D0 (en) * 2008-11-07 2008-12-17 Sportcell Cell compositions and uses thereof
WO2010140162A2 (en) * 2009-05-17 2010-12-09 Dravida Subhadra A process for preparing stem cell based formulations
DE102010046218A1 (de) 2010-09-21 2012-03-22 Livlmplant Gmbh Zell-basiertes Injektionssystem zur Behandlung von Verletzungen
US9044430B2 (en) 2011-03-18 2015-06-02 Microvascular Tissues, Inc. Allogeneic microvascular tissue for soft tissue treatments
WO2014011407A2 (en) 2012-07-12 2014-01-16 Imstem Biotechnology, Inc. Mesenchymal-like stem cells derived from human embryonic stem cells, methods and uses thereof
WO2014047067A1 (en) 2012-09-19 2014-03-27 Tornier, Inc. Compositions and methods for treating and preventing tissue injury and disease
US11819522B2 (en) 2012-09-19 2023-11-21 Microvascular Tissues, Inc. Compositions and methods for treating and preventing tissue injury and disease
US9872937B2 (en) 2012-09-19 2018-01-23 Microvascular Tissues, Inc. Compositions and methods for treating and preventing tissue injury and disease
US10596202B2 (en) 2012-09-19 2020-03-24 Microvascular Tissues, Inc. Compositions and methods for treating and preventing tissue injury and disease
WO2014167142A1 (es) 2013-04-09 2014-10-16 Equicord, S.L. Procedimiento para el tratamiento de células madre mesenquimales equinas y sistema para llevar a cabo el procedimiento
US20140356893A1 (en) 2013-06-04 2014-12-04 Allan Mishra Compositions and methods for using platelet-rich plasma for drug discovery, cell nuclear reprogramming, proliferation or differentiation
DK3083944T3 (da) * 2013-12-19 2021-02-15 Univ Liege Pattedyrsmuskelafledte stamceller
WO2016015007A1 (en) 2014-07-25 2016-01-28 Recellerate, Inc. Methods of treating exercise-induced pulmonary hemorrhage
US10479977B2 (en) 2014-11-07 2019-11-19 The Trustees Of Columbia University In The City Of New York Osteochondroreticular stem cells for bone and cartilage regeneration
RU2644650C2 (ru) 2014-12-01 2018-02-13 Общество с ограниченной ответственностью "Т-Хелпер Клеточные Технологии" Материал стволовых клеток и способ его получения
WO2016172004A1 (en) * 2015-04-18 2016-10-27 The Johns Hopkins University Bone healing, angiogenesis-promoting and vasculogenesis-producing system
WO2017059089A1 (en) * 2015-09-29 2017-04-06 Anicell Biotech, Llc Methods and articles of manufacture for the treatment of animals
US9861410B2 (en) 2016-05-06 2018-01-09 Medos International Sarl Methods, devices, and systems for blood flow
RU2708329C2 (ru) 2016-05-31 2019-12-05 Общество с ограниченной ответственностью "Т-Хелпер Клеточные Технологии" Материал стволовых клеток, композиции и способы применения
CN106308817B (zh) * 2016-08-12 2023-07-28 玉溪九洲生物技术有限责任公司 一种马血浆采集系统
FR3058065B1 (fr) * 2016-10-27 2019-02-01 Scarcell Therapeutics Composition pour le traitement d’une affection de l’appareil locomoteur
EP3388511A1 (de) * 2017-04-12 2018-10-17 Revatis SA Neue verwendungen von säugetiermuskelabgeleiteten stammzellen
WO2021041858A1 (en) * 2019-08-29 2021-03-04 Icahn School Of Medicine At Mount Sinai Differentiated tendon cells derived from pluripotent progenitor cells and methods of use thereof
RU2722162C1 (ru) * 2019-10-14 2020-05-27 Федеральное государственное бюджетное учреждение науки Сибирский федеральный научный центр агробиотехнологий Российской академии наук (СФНЦА РАН) Способ лечения травм сухожильно-связочного аппарата у лошадей

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US5486359A (en) 1990-11-16 1996-01-23 Osiris Therapeutics, Inc. Human mesenchymal stem cells
US5811094A (en) * 1990-11-16 1998-09-22 Osiris Therapeutics, Inc. Connective tissue regeneration using human mesenchymal stem cell preparations
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Also Published As

Publication number Publication date
CA2538187A1 (en) 2004-03-18
US8178084B2 (en) 2012-05-15
AU2003263340B2 (en) 2008-12-18
NZ539308A (en) 2008-03-28
US20120230960A1 (en) 2012-09-13
EP2316462A1 (de) 2011-05-04
EP1545567B1 (de) 2008-03-19
DE60319848T2 (de) 2009-04-30
EP1872789B1 (de) 2011-01-12
CA2538187C (en) 2019-01-08
DE60335752D1 (de) 2011-02-24
EP1545567A1 (de) 2005-06-29
ATE389412T1 (de) 2008-04-15
US20130039896A1 (en) 2013-02-14
AR047712A1 (es) 2006-02-15
ATE494898T1 (de) 2011-01-15
US20150017145A1 (en) 2015-01-15
WO2004022078A1 (en) 2004-03-18
AU2003263340A1 (en) 2004-03-29
US20060130852A1 (en) 2006-06-22
ES2304541T3 (es) 2008-10-16
EP1872789A1 (de) 2008-01-02
US20170258848A1 (en) 2017-09-14

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: QUY BIOSCIENCES LTD., NORWICH NORFOLK, GB