DK1576091T3 - Human adult olefaktorisk stamcelle - Google Patents
Human adult olefaktorisk stamcelleInfo
- Publication number
- DK1576091T3 DK1576091T3 DK03719290.3T DK03719290T DK1576091T3 DK 1576091 T3 DK1576091 T3 DK 1576091T3 DK 03719290 T DK03719290 T DK 03719290T DK 1576091 T3 DK1576091 T3 DK 1576091T3
- Authority
- DK
- Denmark
- Prior art keywords
- olefactory
- stem cells
- human adult
- adult
- human
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0618—Cells of the nervous system
- C12N5/0623—Stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2503/00—Use of cells in diagnostics
- C12N2503/02—Drug screening
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US35290602P | 2002-01-28 | 2002-01-28 | |
US10/112,658 US7838292B1 (en) | 2001-03-29 | 2002-03-29 | Methods for obtaining adult human olfactory progenitor cells |
PCT/US2003/002292 WO2003064601A2 (en) | 2002-01-28 | 2003-01-24 | Adult human olfactory stem cell |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1576091T3 true DK1576091T3 (da) | 2012-11-19 |
Family
ID=27667948
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK03719290.3T DK1576091T3 (da) | 2002-01-28 | 2003-01-24 | Human adult olefaktorisk stamcelle |
Country Status (9)
Country | Link |
---|---|
US (2) | US7838292B1 (da) |
EP (2) | EP1576091B1 (da) |
AU (1) | AU2003223162B8 (da) |
CA (1) | CA2473353C (da) |
DK (1) | DK1576091T3 (da) |
ES (1) | ES2392163T3 (da) |
IL (2) | IL163128A (da) |
PT (1) | PT1576091E (da) |
WO (1) | WO2003064601A2 (da) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2530533C (en) | 2003-06-27 | 2015-02-10 | Ethicon, Incorporated | Postpartum cells derived from umbilical cord tissue, and methods of making and using the same |
US7875273B2 (en) | 2004-12-23 | 2011-01-25 | Ethicon, Incorporated | Treatment of Parkinson's disease and related disorders using postpartum derived cells |
US7875272B2 (en) | 2003-06-27 | 2011-01-25 | Ethicon, Incorporated | Treatment of stroke and other acute neuraldegenerative disorders using postpartum derived cells |
US9592258B2 (en) | 2003-06-27 | 2017-03-14 | DePuy Synthes Products, Inc. | Treatment of neurological injury by administration of human umbilical cord tissue-derived cells |
US8790637B2 (en) | 2003-06-27 | 2014-07-29 | DePuy Synthes Products, LLC | Repair and regeneration of ocular tissue using postpartum-derived cells |
US9572840B2 (en) | 2003-06-27 | 2017-02-21 | DePuy Synthes Products, Inc. | Regeneration and repair of neural tissue using postpartum-derived cells |
WO2007020611A2 (en) * | 2005-08-19 | 2007-02-22 | ECBIO - Investigação e Desenvolvimento em Biotecnologia, S.A. | Adult human neural stem/progenitor cells from the olfactory epithelium and olfactory lamina propria, isolation method, proliferation and differentiation in serum free culture medium and utilization for transplantation |
PL212052B1 (pl) * | 2005-12-14 | 2012-08-31 | Akademia Medyczna Im Piastow Śląskich We Wrocławiu | Sposób pozyskiwania glejowych komórek węchowych i ich zastosowania |
US9175261B2 (en) | 2005-12-16 | 2015-11-03 | DePuy Synthes Products, Inc. | Human umbilical cord tissue cells for inhibiting adverse immune response in histocompatibility-mismatched transplantation |
US8329166B2 (en) * | 2005-12-16 | 2012-12-11 | Academia Sinica | Pluripotent olfactory stem cells |
US9125906B2 (en) | 2005-12-28 | 2015-09-08 | DePuy Synthes Products, Inc. | Treatment of peripheral vascular disease using umbilical cord tissue-derived cells |
WO2008027848A2 (en) * | 2006-08-31 | 2008-03-06 | The University Of Louisville Research Foundation, Inc. | Transcription factors for differentiation of adult human olfactory progenitor cells |
WO2008043142A1 (en) * | 2006-10-11 | 2008-04-17 | Garvan Institute Of Medical Research | Method of treating hearing loss |
DE102008008558A1 (de) * | 2008-02-08 | 2009-08-13 | Phenion Gmbh & Co. Kg | Verfahren zur Gewinnung olfaktorischer Epithelzellen aus nicht-menschlichen embryonalen Stammzellen |
EP2352817B1 (en) * | 2008-10-31 | 2016-01-27 | University Of Louisville Research Foundation, Inc. | Olfactory epithelial-derived stem cells and methods of use therefor |
WO2010071864A1 (en) | 2008-12-19 | 2010-06-24 | Ethicon, Incorporated | Treatment of lung and pulmonary diseases and disorders |
US10179900B2 (en) | 2008-12-19 | 2019-01-15 | DePuy Synthes Products, Inc. | Conditioned media and methods of making a conditioned media |
BRPI1013409A2 (pt) | 2009-03-26 | 2018-01-16 | Advanced Tech And Regenerative Medicine Llc | células de tecido de cordão umbilical humano como terapia para doença de alzheimer |
CA2825553A1 (en) * | 2011-01-24 | 2012-08-02 | California Stem Cell, Inc. | Neural cell purification for transplantation |
WO2012164137A1 (es) | 2011-05-30 | 2012-12-06 | Fundación Investigación En Regeneración Del Sistema Nervioso | Células madre y células de la estirpe neural derivadas de la glía envolvente olfatoria, y sus aplicaciones |
WO2013063389A2 (en) * | 2011-10-26 | 2013-05-02 | University Of Louisville Research Foundation, Inc. | Methods and compositions for treating diabetes and other degenerative neuroendocrine diseases or disorders |
BR112014015424A2 (pt) | 2011-12-23 | 2018-05-22 | Depuy Synthes Products Llc | detecção de células derivadas de tecido do cordão umbilical humano |
US9861663B2 (en) * | 2012-02-23 | 2018-01-09 | Technion Research & Development Foundation Ltd. | Ex-vivo vascularized implant composition comprising poly-l-lactic acid, polylactic-co-glycolic-acid and olfactory bulb cells |
Family Cites Families (73)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4863899A (en) | 1983-05-09 | 1989-09-05 | Todaro George J | Biologically active polypeptides |
US5240912A (en) | 1983-05-09 | 1993-08-31 | Todaro George J | Transforming growth factor (TGF) peptides |
US5223409A (en) | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
US5459039A (en) | 1989-05-12 | 1995-10-17 | Duke University | Methods for mapping genetic mutations |
EP0402226A1 (en) | 1989-06-06 | 1990-12-12 | Institut National De La Recherche Agronomique | Transformation vectors for yeast yarrowia |
US5411883A (en) * | 1989-12-26 | 1995-05-02 | Somatix Therapy Corporation | Proliferated neuron progenitor cell product and process |
WO1991009936A1 (en) | 1989-12-26 | 1991-07-11 | Hana Biologics, Inc. | Proliferated neuron progenitor cell product and process |
US5869266A (en) * | 1990-03-06 | 1999-02-09 | The United States Of America As Represented By The Department Of Health And Human Services | Human olfactory neuron cultures to diagnose Alzheimer's disease |
US5196315A (en) | 1990-05-01 | 1993-03-23 | The Johns Hopkins University | Human neuronal cell line |
US5618531A (en) | 1990-10-19 | 1997-04-08 | New York University | Method for increasing the viability of cells which are administered to the brain or spinal cord |
US5217893A (en) | 1990-12-31 | 1993-06-08 | The Johns Hopkins University | Primary culture of olfactory neurons |
US7361505B1 (en) | 1991-07-08 | 2008-04-22 | Neurospheres Holdings Ltd. | Multipotent neural stem cell compositions |
US5981165A (en) | 1991-07-08 | 1999-11-09 | Neurospheres Holdings Ltd. | In vitro induction of dopaminergic cells |
US6497872B1 (en) | 1991-07-08 | 2002-12-24 | Neurospheres Holdings Ltd. | Neural transplantation using proliferated multipotent neural stem cells and their progeny |
US5980885A (en) * | 1991-07-08 | 1999-11-09 | Neurospheres Holdings Ltd. | Growth factor-induced proliferation of neural precursor cells in vivo |
US6071889A (en) | 1991-07-08 | 2000-06-06 | Neurospheres Holdings Ltd. | In vivo genetic modification of growth factor-responsive neural precursor cells |
US5851832A (en) | 1991-07-08 | 1998-12-22 | Neurospheres, Ltd. | In vitro growth and proliferation of multipotent neural stem cells and their progeny |
US7166277B1 (en) | 1991-07-08 | 2007-01-23 | Neurospheres Holdings Ltd. | Remyelination of neurons using multipotent neural stem cell progeny |
US6294346B1 (en) | 1991-07-08 | 2001-09-25 | Neurospheres Holdings, Ltd. | Use of multipotent neural stem cells and their progeny for the screening of drugs and other biological agents |
US5750376A (en) * | 1991-07-08 | 1998-05-12 | Neurospheres Holdings Ltd. | In vitro growth and proliferation of genetically modified multipotent neural stem cells and their progeny |
US6399369B1 (en) | 1991-07-08 | 2002-06-04 | Neurospheres Holdings Ltd. | Multipotent neural stem cell cDNA libraries |
US5308763A (en) | 1991-10-01 | 1994-05-03 | The Johns Hopkins University | Method of making primary culture of olfactory neurons |
US5766948A (en) | 1993-01-06 | 1998-06-16 | The Regents Of The University Of California | Method for production of neuroblasts |
US6001654A (en) | 1994-01-28 | 1999-12-14 | California Institute Of Technology | Methods for differentiating neural stem cells to neurons or smooth muscle cells using TGT-β super family growth factors |
DE69532679T2 (de) | 1994-11-08 | 2005-03-03 | Cellfactors Plc | Methode zur herstellung einer menschlichen neuralen zelllinie |
US5843780A (en) | 1995-01-20 | 1998-12-01 | Wisconsin Alumni Research Foundation | Primate embryonic stem cells |
US5830651A (en) | 1995-06-01 | 1998-11-03 | Signal Pharmaceuticals, Inc. | Human oligodendroglial progenitor cell line |
US5753505A (en) | 1995-07-06 | 1998-05-19 | Emory University | Neuronal progenitor cells and uses thereof |
US7544511B2 (en) | 1996-09-25 | 2009-06-09 | Neuralstem Biopharmaceuticals Ltd. | Stable neural stem cell line methods |
US5753506A (en) | 1996-05-23 | 1998-05-19 | Cns Stem Cell Technology, Inc. | Isolation propagation and directed differentiation of stem cells from embryonic and adult central nervous system of mammals |
CA2213780C (en) | 1996-08-26 | 2012-02-21 | Freda Miller | Pharmaceuticals containing multipotential precursor cells from tissues containing sensory receptors |
US6969608B1 (en) | 1996-08-26 | 2005-11-29 | Mcgill University | Pharmaceuticals containing multipotential precursor cells from tissues containing sensory receptors |
US6787355B1 (en) | 1996-08-26 | 2004-09-07 | Mcgill University | Multipotent neural stem cells from peripheral tissues and uses thereof |
CA2216439A1 (en) | 1996-09-25 | 1998-03-25 | Derek Van Der Kooy | Pharmaceuticals containing retinal stem cells |
WO1998030678A1 (en) | 1997-01-07 | 1998-07-16 | Steindler Dennis A | Isolated mammalian neural stem cells, methods of making such cells, and methods of using such cells |
US6162428A (en) | 1997-02-12 | 2000-12-19 | Layton Bioscience, Inc. | hNT-neuron human neuronal cells to replace ganglion cells |
US6235527B1 (en) | 1997-11-29 | 2001-05-22 | University Of Utah Research Foundation | Lineage restricted glial precursors from the central nervous system |
US20020016002A1 (en) | 2000-01-24 | 2002-02-07 | Jean Toma | Multipotent neural stem cells from peripheral tissues and uses thereof |
US20020123143A1 (en) | 1997-08-22 | 2002-09-05 | Jean Toma | Multipotent stem cells from peripheral tissues and uses thereof |
US5968829A (en) | 1997-09-05 | 1999-10-19 | Cytotherapeutics, Inc. | Human CNS neural stem cells |
US6093531A (en) | 1997-09-29 | 2000-07-25 | Neurospheres Holdings Ltd. | Generation of hematopoietic cells from multipotent neural stem cells |
US6638501B1 (en) | 1997-09-29 | 2003-10-28 | Neurospheres Holdings Ltd. | Use of multipotent neural stem cell progeny to augment non-neural tissues |
US6165783A (en) | 1997-10-24 | 2000-12-26 | Neuro Spheres Holdings Ltd. | Erythropoietin-mediated neurogenesis |
US6129911A (en) | 1998-07-10 | 2000-10-10 | Rhode Island Hospital, A Lifespan Partner | Liver stem cell |
US5958767A (en) | 1998-08-14 | 1999-09-28 | The Children's Medical Center Corp. | Engraftable human neural stem cells |
US6284539B1 (en) | 1998-10-09 | 2001-09-04 | Neuralstem Biopharmaceuticals, Ltd. | Method for generating dopaminergic cells derived from neural precursors |
US6468794B1 (en) | 1999-02-12 | 2002-10-22 | Stemcells, Inc. | Enriched central nervous system stem cell and progenitor cell populations, and methods for identifying, isolating and enriching for such populations |
US6238922B1 (en) | 1999-02-26 | 2001-05-29 | Stemcells, Inc. | Use of collagenase in the preparation of neural stem cell cultures |
US20020099008A1 (en) | 1999-04-26 | 2002-07-25 | Daniel R. Twardzik | Method for stimulating hematopoiesis using tgf-alpha |
JP2002543096A (ja) | 1999-04-26 | 2002-12-17 | ステム セル ファーマシューティカルズ,インコーポレーテッド | TGF−αポリペプチド、機能性断片およびそれらの利用法 |
JP2003508018A (ja) | 1999-05-06 | 2003-03-04 | ステム・セル・サイエンシイズ・ピーティーワイ・リミテッド | 異核共存体の作成を介した細胞のリプログラミング法 |
CA2377906A1 (en) | 1999-07-16 | 2001-01-25 | Neurotrophic Bioscience, Inc. | Methods for producing and preparing cells for cell therapy |
US20020193301A1 (en) | 1999-08-19 | 2002-12-19 | Stem Cell Pharmaceuticals, Inc. | TGF-alpha polypeptides, functional fragments and methods of use therefor |
US6815418B2 (en) | 1999-08-19 | 2004-11-09 | Kaleidos Pharma, Inc. | TGF-α polypeptides, functional fragments and methods of use therefor |
US6677307B2 (en) | 1999-08-19 | 2004-01-13 | Kaleidos Pharma, Inc. | TGF-α polypeptides, functional fragments and methods of use therefor |
US6878543B1 (en) | 1999-10-25 | 2005-04-12 | Nsgene Sa | Cultures of GFAP+ nestin+ cells that differentiate to neurons |
AUPQ369599A0 (en) | 1999-10-27 | 1999-11-18 | Griffith University | A method of preparing olfactory cells for transplantation |
US7544509B2 (en) | 2000-01-24 | 2009-06-09 | Mcgill University | Method for preparing stem cell preparations |
US20020169102A1 (en) | 2001-04-03 | 2002-11-14 | Frey William H. | Intranasal delivery of agents for regulating development of implanted cells in the CNS |
WO2002083877A1 (en) | 2001-04-11 | 2002-10-24 | Stem Cell Therapeutics Inc. | Production of tyrosine hydroxylase positive neurons |
US7132286B2 (en) | 2001-06-18 | 2006-11-07 | Psychiatric Genomics, Inc. | Method for neural stem cell differentiation using valproate |
ES2292772T3 (es) | 2001-06-22 | 2008-03-16 | Stemcells, Inc. | Celulas de injerto de higado, analisis, y sus usos. |
CA2364095C (en) | 2001-07-20 | 2011-07-12 | Neurostasis, Inc | Production of radial glial cells |
EP1423509A2 (en) | 2001-08-30 | 2004-06-02 | Stem Cell Therapeutics Inc. | Differentiation of neural stem cells and therapeutic use thereof |
EP1430114B1 (en) | 2001-09-14 | 2012-01-18 | Stem Cell Therapeutics Inc. | Prolactin induced increase in neural stem cell numbers and therapeutical use thereof |
WO2003063585A1 (en) | 2002-01-31 | 2003-08-07 | Griffith University | Animal model |
WO2004011632A2 (en) | 2002-07-30 | 2004-02-05 | Stem Cell Therapeutics Inc. | Oligodendrocyte production from multipotent neural stem cells |
US7368115B2 (en) | 2002-07-31 | 2008-05-06 | Stem Cell Therapeutics Inc. | Method of enhancing neural stem cell proliferation, differentiation, and survival using pituitary adenylate cyclase activating polypeptide (PACAP) |
WO2004053071A2 (en) | 2002-12-09 | 2004-06-24 | Judith Kelleher-Andersson | Method for discovering neurogenic agents |
ES2579804T3 (es) | 2003-12-02 | 2016-08-16 | Celavie Biosciences, Llc | Composiciones y métodos para la propagación de células progenitoras neurales |
KR101505347B1 (ko) | 2004-11-17 | 2015-03-23 | 뉴럴스템, 인크. | 신경퇴행성 증상의 치료를 위한 인간 신경 세포의 이식 |
US7629169B2 (en) | 2004-12-01 | 2009-12-08 | Stem Cell Therapeutics Corp. | Methods for the production of platelet-derived growth factor-responsive neural precursor cells |
AU2006297041A1 (en) | 2005-09-27 | 2007-04-05 | Stem Cell Therapeutics Corp. | Oligodendrocyte precursor cell proliferation regulated by prolactin |
-
2002
- 2002-03-29 US US10/112,658 patent/US7838292B1/en not_active Expired - Fee Related
-
2003
- 2003-01-24 CA CA2473353A patent/CA2473353C/en not_active Expired - Fee Related
- 2003-01-24 ES ES03719290T patent/ES2392163T3/es not_active Expired - Lifetime
- 2003-01-24 EP EP03719290A patent/EP1576091B1/en not_active Expired - Lifetime
- 2003-01-24 DK DK03719290.3T patent/DK1576091T3/da active
- 2003-01-24 AU AU2003223162A patent/AU2003223162B8/en not_active Ceased
- 2003-01-24 PT PT37192903T patent/PT1576091E/pt unknown
- 2003-01-24 WO PCT/US2003/002292 patent/WO2003064601A2/en not_active Application Discontinuation
- 2003-01-24 EP EP20110152100 patent/EP2308962A1/en not_active Withdrawn
-
2004
- 2004-07-21 IL IL163128A patent/IL163128A/en not_active IP Right Cessation
-
2010
- 2010-09-14 IL IL208130A patent/IL208130A0/en unknown
- 2010-09-23 US US12/888,826 patent/US20110014695A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
EP1576091A2 (en) | 2005-09-21 |
EP1576091A4 (en) | 2008-07-02 |
EP1576091B1 (en) | 2012-09-12 |
US7838292B1 (en) | 2010-11-23 |
WO2003064601A2 (en) | 2003-08-07 |
CA2473353C (en) | 2016-01-19 |
ES2392163T3 (es) | 2012-12-05 |
IL208130A0 (en) | 2011-07-31 |
PT1576091E (pt) | 2012-12-04 |
EP2308962A1 (en) | 2011-04-13 |
CA2473353A1 (en) | 2003-08-07 |
WO2003064601A8 (en) | 2004-04-29 |
AU2003223162B8 (en) | 2010-01-07 |
AU2003223162B2 (en) | 2009-06-04 |
IL163128A (en) | 2010-12-30 |
US20110014695A1 (en) | 2011-01-20 |
AU2003223162A1 (en) | 2003-09-18 |
WO2003064601A3 (en) | 2007-11-22 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DK1576091T3 (da) | Human adult olefaktorisk stamcelle | |
DE60319848D1 (de) | Medikament mit mesenchym-stammzellen | |
DE10393673D2 (de) | Wirbelkörperplatzhalter | |
DE10393091D2 (de) | Wirbelkörperplatzhalter | |
ATE409447T1 (de) | Bequem windel | |
DE60312054D1 (de) | Prothese | |
ATE390898T1 (de) | Zwischenwirbelimplantat | |
ATE394087T1 (de) | Zwischenwirbelimplantat | |
ATE394086T1 (de) | Zwischenwirbelimplantat | |
IS7663A (is) | Starfrænar hjartavöðvafrumur úr mannafósturstofnfrumum | |
ES1054821Y (es) | Peonza de juguete | |
DE60327986D1 (de) | Sitzstruktur | |
DE60314931D1 (de) | Sitzstruktur | |
GB2427616B (en) | Stem cells | |
AU2003247514A8 (en) | Meningeal-derived stem cells | |
DE50308359D1 (de) | Armlehne | |
DE50308343D1 (de) | Armlehne | |
EP1637589A4 (en) | NEW STEM CELL DERIVED FROM ADULT FABRIC AND THEIR USE | |
FR2837877B1 (fr) | Modele de superstatoreacteur | |
DE60313015D1 (de) | Künstlicher satellit | |
FR2843017B1 (fr) | Implant inter-somatique | |
GB0207299D0 (en) | Stem cell therapy | |
DE10392685D2 (de) | Sitzmöbel | |
NO20022747D0 (no) | Behandlingsstol | |
FI20021353A (fi) | Istuin |