NZ542586A - Method of forming a covalent conjugate between a G-CSF peptide and PEG - Google Patents
Method of forming a covalent conjugate between a G-CSF peptide and PEGInfo
- Publication number
- NZ542586A NZ542586A NZ542586A NZ54258604A NZ542586A NZ 542586 A NZ542586 A NZ 542586A NZ 542586 A NZ542586 A NZ 542586A NZ 54258604 A NZ54258604 A NZ 54258604A NZ 542586 A NZ542586 A NZ 542586A
- Authority
- NZ
- New Zealand
- Prior art keywords
- poly
- ethylene glycol
- csf peptide
- forming
- covalent conjugate
- Prior art date
Links
- 108010017080 Granulocyte Colony-Stimulating Factor Proteins 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 4
- -1 poly(ethylene glycol) Polymers 0.000 abstract 8
- 229920001223 polyethylene glycol Polymers 0.000 abstract 4
- 239000002773 nucleotide Substances 0.000 abstract 2
- 125000003729 nucleotide group Chemical group 0.000 abstract 2
- 102000051366 Glycosyltransferases Human genes 0.000 abstract 1
- 108700023372 Glycosyltransferases Proteins 0.000 abstract 1
- 230000004913 activation Effects 0.000 abstract 1
- 230000004069 differentiation Effects 0.000 abstract 1
- 125000003147 glycosyl group Chemical group 0.000 abstract 1
- 238000000338 in vitro Methods 0.000 abstract 1
- 125000005647 linker group Chemical group 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000035755 proliferation Effects 0.000 abstract 1
- 210000000130 stem cell Anatomy 0.000 abstract 1
- 239000000758 substrate Substances 0.000 abstract 1
Classifications
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- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6424—Serine endopeptidases (3.4.21)
- C12N9/6437—Coagulation factor VIIa (3.4.21.21)
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Applications Claiming Priority (14)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/411,037 US7125843B2 (en) | 2001-10-19 | 2003-04-09 | Glycoconjugates including more than one peptide |
| US10/411,044 US8008252B2 (en) | 2001-10-10 | 2003-04-09 | Factor VII: remodeling and glycoconjugation of Factor VII |
| US10/411,049 US7297511B2 (en) | 2001-10-10 | 2003-04-09 | Interferon alpha: remodeling and glycoconjugation of interferon alpha |
| US10/411,012 US7265084B2 (en) | 2001-10-10 | 2003-04-09 | Glycopegylation methods and proteins/peptides produced by the methods |
| US10/410,962 US7173003B2 (en) | 2001-10-10 | 2003-04-09 | Granulocyte colony stimulating factor: remodeling and glycoconjugation of G-CSF |
| US10/410,945 US7214660B2 (en) | 2001-10-10 | 2003-04-09 | Erythropoietin: remodeling and glycoconjugation of erythropoietin |
| US10/410,897 US7179617B2 (en) | 2001-10-10 | 2003-04-09 | Factor IX: remolding and glycoconjugation of Factor IX |
| US10/411,026 US7795210B2 (en) | 2001-10-10 | 2003-04-09 | Protein remodeling methods and proteins/peptides produced by the methods |
| US10/410,980 US7399613B2 (en) | 2001-10-10 | 2003-04-09 | Sialic acid nucleotide sugars |
| US10/410,930 US7226903B2 (en) | 2001-10-10 | 2003-04-09 | Interferon beta: remodeling and glycoconjugation of interferon beta |
| US10/411,043 US7439043B2 (en) | 2001-10-10 | 2003-04-09 | Galactosyl nucleotide sugars |
| US10/410,997 US7157277B2 (en) | 2001-11-28 | 2003-04-09 | Factor VIII remodeling and glycoconjugation of Factor VIII |
| US10/410,913 US7265085B2 (en) | 2001-10-10 | 2003-04-09 | Glycoconjugation methods and proteins/peptides produced by the methods |
| PCT/US2004/011494 WO2004099231A2 (en) | 2003-04-09 | 2004-04-09 | Glycopegylation methods and proteins/peptides produced by the methods |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NZ542586A true NZ542586A (en) | 2009-11-27 |
Family
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| Application Number | Title | Priority Date | Filing Date |
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| NZ542586A NZ542586A (en) | 2003-04-09 | 2004-04-09 | Method of forming a covalent conjugate between a G-CSF peptide and PEG |
Country Status (14)
| Country | Link |
|---|---|
| US (6) | US20070026485A1 (OSRAM) |
| EP (3) | EP1615945B1 (OSRAM) |
| JP (1) | JP4674702B2 (OSRAM) |
| AU (1) | AU2004236174B2 (OSRAM) |
| BE (1) | BE2014C003I2 (OSRAM) |
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| IL (1) | IL171109A (OSRAM) |
| LU (1) | LU92358I2 (OSRAM) |
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| NZ (1) | NZ542586A (OSRAM) |
| PL (1) | PL1615945T3 (OSRAM) |
| SG (1) | SG155777A1 (OSRAM) |
| WO (1) | WO2004099231A2 (OSRAM) |
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| US8008252B2 (en) | 2001-10-10 | 2011-08-30 | Novo Nordisk A/S | Factor VII: remodeling and glycoconjugation of Factor VII |
| US7696163B2 (en) | 2001-10-10 | 2010-04-13 | Novo Nordisk A/S | Erythropoietin: remodeling and glycoconjugation of erythropoietin |
| US7157277B2 (en) | 2001-11-28 | 2007-01-02 | Neose Technologies, Inc. | Factor VIII remodeling and glycoconjugation of Factor VIII |
| DE60336555D1 (de) * | 2002-06-21 | 2011-05-12 | Novo Nordisk Healthcare Ag | Pegylierte glykoformen von faktor vii |
| SI1596887T1 (sl) | 2003-02-26 | 2022-05-31 | Nektar Therapeutics | Konjugati polimer-del faktorja VIII |
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| AU2004236174B2 (en) | 2011-06-02 |
| US8063015B2 (en) | 2011-11-22 |
| US20150343080A1 (en) | 2015-12-03 |
| US8853161B2 (en) | 2014-10-07 |
| US20140294762A1 (en) | 2014-10-02 |
| US20120220517A1 (en) | 2012-08-30 |
| WO2004099231A2 (en) | 2004-11-18 |
| JP2007525941A (ja) | 2007-09-13 |
| BE2014C003I2 (OSRAM) | 2023-08-09 |
| EP1615945A2 (en) | 2006-01-18 |
| LU92358I2 (fr) | 2014-03-24 |
| EP1615945B1 (en) | 2011-09-28 |
| MXPA05010773A (es) | 2005-12-12 |
| US20070026485A1 (en) | 2007-02-01 |
| JP4674702B2 (ja) | 2011-04-20 |
| US20170007712A1 (en) | 2017-01-12 |
| SG155777A1 (en) | 2009-10-29 |
| AU2004236174A1 (en) | 2004-11-18 |
| EP2338333A3 (en) | 2011-07-27 |
| CA2522345A1 (en) | 2004-11-18 |
| IL171109A (en) | 2015-09-24 |
| EP2055189A1 (en) | 2009-05-06 |
| WO2004099231A3 (en) | 2006-03-16 |
| LU92358I9 (OSRAM) | 2024-06-18 |
| CY1114626T1 (el) | 2016-10-05 |
| EP1615945A4 (en) | 2007-10-17 |
| EP2338333B1 (en) | 2017-09-06 |
| EP2338333A2 (en) | 2011-06-29 |
| US20100048456A1 (en) | 2010-02-25 |
| PL1615945T3 (pl) | 2012-03-30 |
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