PL1615945T3 - Sposoby glikopegylacji i białka/peptydy wytwarzane tymi sposobami - Google Patents

Sposoby glikopegylacji i białka/peptydy wytwarzane tymi sposobami

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Publication number
PL1615945T3
PL1615945T3 PL04750118T PL04750118T PL1615945T3 PL 1615945 T3 PL1615945 T3 PL 1615945T3 PL 04750118 T PL04750118 T PL 04750118T PL 04750118 T PL04750118 T PL 04750118T PL 1615945 T3 PL1615945 T3 PL 1615945T3
Authority
PL
Poland
Prior art keywords
methods
proteins
glycopegylation
peptides produced
peptides
Prior art date
Application number
PL04750118T
Other languages
English (en)
Inventor
Frees Shawn De
David Zopf
Robert Bayer
Caryn Bowe
David Hakes
Xi Chen
Original Assignee
Ratiopharm Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/410,930 external-priority patent/US7226903B2/en
Priority claimed from US10/411,012 external-priority patent/US7265084B2/en
Priority claimed from US10/411,049 external-priority patent/US7297511B2/en
Priority claimed from US10/410,962 external-priority patent/US7173003B2/en
Priority claimed from US10/411,043 external-priority patent/US7439043B2/en
Priority claimed from US10/411,037 external-priority patent/US7125843B2/en
Priority claimed from US10/410,945 external-priority patent/US7214660B2/en
Priority claimed from US10/410,897 external-priority patent/US7179617B2/en
Priority claimed from US10/410,997 external-priority patent/US7157277B2/en
Priority claimed from US10/411,026 external-priority patent/US7795210B2/en
Priority claimed from US10/411,044 external-priority patent/US8008252B2/en
Priority claimed from US10/410,913 external-priority patent/US7265085B2/en
Priority claimed from US10/410,980 external-priority patent/US7399613B2/en
Application filed by Ratiopharm Gmbh filed Critical Ratiopharm Gmbh
Publication of PL1615945T3 publication Critical patent/PL1615945T3/pl

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    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424Serine endopeptidases (3.4.21)
    • C12N9/6437Coagulation factor VIIa (3.4.21.21)
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    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/1072General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
    • C07K1/1077General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups by covalent attachment of residues other than amino acids or peptide residues, e.g. sugars, polyols, fatty acids
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US10/411,049 US7297511B2 (en) 2001-10-10 2003-04-09 Interferon alpha: remodeling and glycoconjugation of interferon alpha
US10/410,962 US7173003B2 (en) 2001-10-10 2003-04-09 Granulocyte colony stimulating factor: remodeling and glycoconjugation of G-CSF
US10/411,043 US7439043B2 (en) 2001-10-10 2003-04-09 Galactosyl nucleotide sugars
US10/411,037 US7125843B2 (en) 2001-10-19 2003-04-09 Glycoconjugates including more than one peptide
US10/410,930 US7226903B2 (en) 2001-10-10 2003-04-09 Interferon beta: remodeling and glycoconjugation of interferon beta
US10/410,897 US7179617B2 (en) 2001-10-10 2003-04-09 Factor IX: remolding and glycoconjugation of Factor IX
US10/411,012 US7265084B2 (en) 2001-10-10 2003-04-09 Glycopegylation methods and proteins/peptides produced by the methods
US10/411,026 US7795210B2 (en) 2001-10-10 2003-04-09 Protein remodeling methods and proteins/peptides produced by the methods
US10/411,044 US8008252B2 (en) 2001-10-10 2003-04-09 Factor VII: remodeling and glycoconjugation of Factor VII
US10/410,913 US7265085B2 (en) 2001-10-10 2003-04-09 Glycoconjugation methods and proteins/peptides produced by the methods
US10/410,980 US7399613B2 (en) 2001-10-10 2003-04-09 Sialic acid nucleotide sugars
US10/410,997 US7157277B2 (en) 2001-11-28 2003-04-09 Factor VIII remodeling and glycoconjugation of Factor VIII
US10/410,945 US7214660B2 (en) 2001-10-10 2003-04-09 Erythropoietin: remodeling and glycoconjugation of erythropoietin
EP04750118A EP1615945B1 (en) 2003-04-09 2004-04-09 Glycopegylation methods and proteins/peptides produced by the methods
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EP2338333B1 (en) 2017-09-06
AU2004236174B2 (en) 2011-06-02
US20120220517A1 (en) 2012-08-30
WO2004099231A3 (en) 2006-03-16
CA2522345A1 (en) 2004-11-18
EP2338333A2 (en) 2011-06-29
US20070026485A1 (en) 2007-02-01
WO2004099231A2 (en) 2004-11-18
LU92358I2 (fr) 2014-03-24
BE2014C003I2 (pl) 2023-08-09
US20150343080A1 (en) 2015-12-03
EP2338333A3 (en) 2011-07-27
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US20100048456A1 (en) 2010-02-25
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US8853161B2 (en) 2014-10-07
IL171109A (en) 2015-09-24
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US8063015B2 (en) 2011-11-22
US20140294762A1 (en) 2014-10-02
CY1114626T1 (el) 2016-10-05
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EP1615945A4 (en) 2007-10-17
JP4674702B2 (ja) 2011-04-20

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