ATE42338T1 - Hefe des genus kluyveromyces, modifiziert zur expression von preprothaumatin oder seinen verschiedenen allelischen und modifizierten formen oder maturationsformen. - Google Patents

Hefe des genus kluyveromyces, modifiziert zur expression von preprothaumatin oder seinen verschiedenen allelischen und modifizierten formen oder maturationsformen.

Info

Publication number
ATE42338T1
ATE42338T1 AT83200712T AT83200712T ATE42338T1 AT E42338 T1 ATE42338 T1 AT E42338T1 AT 83200712 T AT83200712 T AT 83200712T AT 83200712 T AT83200712 T AT 83200712T AT E42338 T1 ATE42338 T1 AT E42338T1
Authority
AT
Austria
Prior art keywords
modified
forms
preprothaumatin
yeast
expression
Prior art date
Application number
AT83200712T
Other languages
English (en)
Inventor
Luppo Edens
Adrianus Marinus Ledeboer
Cornelis Theodorus Verrips
Den Berg Johannes Abel Van
Original Assignee
Unilever Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=19839766&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE42338(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Unilever Nv filed Critical Unilever Nv
Application granted granted Critical
Publication of ATE42338T1 publication Critical patent/ATE42338T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405—Glucanases
    • C12N9/2408—Glucanases acting on alpha -1,4-glucosidic bonds
    • C12N9/2411—Amylases
    • C12N9/2428—Glucan 1,4-alpha-glucosidase (3.2.1.3), i.e. glucoamylase
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • C07K14/43—Sweetening agents, e.g. thaumatin, monellin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/67—General methods for enhancing the expression
    • C12N15/68—Stabilisation of the vector
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C12N15/815—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts for yeasts other than Saccharomyces
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/90—Stable introduction of foreign DNA into chromosome
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6478—Aspartic endopeptidases (3.4.23)
    • C12N9/6481—Pepsins (3.4.23.1; 3.4.23.2; 3.4.23.3)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/036—Fusion polypeptide containing a localisation/targetting motif targeting to the medium outside of the cell, e.g. type III secretion

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Mycology (AREA)
  • Botany (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pyrane Compounds (AREA)
AT83200712T 1982-05-19 1983-05-19 Hefe des genus kluyveromyces, modifiziert zur expression von preprothaumatin oder seinen verschiedenen allelischen und modifizierten formen oder maturationsformen. ATE42338T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NL8202091 1982-05-19
EP83200712A EP0096910B1 (de) 1982-05-19 1983-05-19 Hefe des Genus Kluyveromyces, modifiziert zur Expression von Preprothaumatin oder seinen verschiedenen allelischen und modifizierten Formen oder Maturationsformen

Publications (1)

Publication Number Publication Date
ATE42338T1 true ATE42338T1 (de) 1989-05-15

Family

ID=19839766

Family Applications (2)

Application Number Title Priority Date Filing Date
AT83200714T ATE49421T1 (de) 1982-05-19 1983-05-19 Klonierungssystem fuer kluyveromyce spezies.
AT83200712T ATE42338T1 (de) 1982-05-19 1983-05-19 Hefe des genus kluyveromyces, modifiziert zur expression von preprothaumatin oder seinen verschiedenen allelischen und modifizierten formen oder maturationsformen.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT83200714T ATE49421T1 (de) 1982-05-19 1983-05-19 Klonierungssystem fuer kluyveromyce spezies.

Country Status (20)

Country Link
US (2) US4657857A (de)
EP (2) EP0096910B1 (de)
JP (3) JPS59501572A (de)
AR (1) AR241796A1 (de)
AT (2) ATE49421T1 (de)
AU (1) AU571181B2 (de)
BR (1) BR8307525A (de)
CA (1) CA1224735A (de)
DE (2) DE3379665D1 (de)
DK (1) DK173699B1 (de)
ES (1) ES8402874A1 (de)
FI (1) FI81379C (de)
GR (1) GR78852B (de)
HU (1) HU204097B (de)
IE (1) IE55817B1 (de)
IL (1) IL68733A (de)
NO (1) NO172397C (de)
NZ (1) NZ204302A (de)
PT (1) PT76727B (de)
WO (2) WO1983004051A1 (de)

Families Citing this family (64)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58146281A (ja) * 1981-10-19 1983-08-31 Suntory Ltd 酵母細胞の形質転換法
IE55817B1 (en) * 1982-05-19 1991-01-30 Gist Brocades Nv Cloning system for kluyveromyces species
US4943529A (en) 1982-05-19 1990-07-24 Gist-Brocades Nv Kluyveromyces as a host strain
JPH0716432B2 (ja) * 1982-10-20 1995-03-01 サントリー株式会社 酵母の高発現ベクタープラスミドを用いたペプチドの生産方法
CA1341116C (en) * 1983-02-22 2000-10-17 Rae Lyn Burke Yeast expression systems with vectors having gapdh or pyk promoters and synthesis or foreign protein
US4876197A (en) * 1983-02-22 1989-10-24 Chiron Corporation Eukaryotic regulatable transcription
WO1984004538A1 (fr) * 1983-05-19 1984-11-22 Unilever Nv Ameliorations apportees a l'expression de genes fraichement introduits dans des cellules de levure
AU577334B2 (en) * 1983-10-11 1988-09-22 International Genetic Engineering, Inc. Synthetic thaumatin genes
US5422267A (en) * 1984-05-22 1995-06-06 Robert R. Yocum Industrial yeast comprising an integrated glucoamylase gene
IL75210A0 (en) * 1984-05-22 1985-09-29 Bioteknika International Yeast vector
US6214577B1 (en) 1984-05-22 2001-04-10 Robert Rogers Yocum Yeast vectors conferring antibiotic resistance
US5741672A (en) * 1984-07-27 1998-04-21 Unilever Patent Holdings B.V. Expression and production of polypeptides using the promoters of the hansenula polymorpha MOX and DAS genes
US5240838A (en) * 1984-07-27 1993-08-31 Internationale Otrool Maatschappij "Octropa" B.V. Regulatory sequences of alcohol oxidase (MOX) and dihydroxyacetonesynthase (DAS) of Hansenula polymorpha
US4879231A (en) * 1984-10-30 1989-11-07 Phillips Petroleum Company Transformation of yeasts of the genus pichia
US4837148A (en) * 1984-10-30 1989-06-06 Phillips Petroleum Company Autonomous replication sequences for yeast strains of the genus pichia
US4855231A (en) * 1984-10-30 1989-08-08 Phillips Petroleum Company Regulatory region for heterologous gene expression in yeast
US5047340A (en) * 1985-06-05 1991-09-10 The University Of Kentucky Research Foundation LAC+ saccharomyces cerevisiae
CA1310923C (en) * 1985-11-13 1992-12-01 Joachim Ludwig Weickmann Dna encoding [asp --] and [lys -, asp --] thaumatin i
IT1203758B (it) * 1986-03-27 1989-02-23 Univ Roma Vettori di clonazione e di espressione di geni eterologhi in lieviti e lieviti trasformati con tali vettori
CA1339101C (en) * 1986-06-03 1997-07-29 Nicolaas Overbeeke Production of guar alpha-galactosidase and immunologically related alpha-galactosidases by host organisms transformed with recombinant dna methods
EP0260404B1 (de) * 1986-08-21 1995-05-31 VAN DEN BERG, Robert Durch rekombinante DNS-Technologie konstruierte amylolytische enzymproduzierende Mikroorganismen und ihre Verwendung in Gärungsverfahren
US5151354A (en) * 1986-08-21 1992-09-29 Cornelius Hollenberg Fermentation processes using amylolytic enzyme producing microorganisms
EP0257115A1 (de) * 1986-08-21 1988-03-02 Heineken Technisch Beheer B.V. Durch rekombinante DNS-Technologie konstruierte amylolytische enzymproduzierende Mikroorganismen und ihre Verwendung in Gärungsverfahren
US5882884A (en) * 1987-06-19 1999-03-16 Lucky Biotech Corporation Expression of proteinaceous sweeteners in yeast
ES2061632T5 (es) * 1987-07-28 2000-12-16 Dsm Nv Kluyveromyces como celula hospedante.
FR2649991B2 (fr) 1988-08-05 1994-03-04 Rhone Poulenc Sante Utilisation de derives stables du plasmide pkd1 pour l'expression et la secretion de proteines heterologues dans les levures du genre kluyveromyces
US5221624A (en) * 1988-11-08 1993-06-22 International Genetic Engineering, Inc. DNA encoding (Lys46, Asp97, Asp113) and (Lys46, Asp.sup.137) thaumatin I polypeptides
US5204252A (en) * 1989-02-08 1993-04-20 Henkel Research Corporation Candida tropicalis transformation system
DK0413019T3 (da) * 1989-02-24 2001-11-12 Monsanto Technology Llc Syntetiske plantegener og fremgangsmåde til fremstilling af disse
US20010003849A1 (en) 1989-08-07 2001-06-14 Kenneth A. Barton Expression of genes in plants
US5264554A (en) * 1990-01-19 1993-11-23 The Blood Center Of Southeastern Wisconsin, Inc. Platelet cell adhesion molecule and variants thereof
FR2678636A1 (fr) * 1991-07-02 1993-01-08 Rhone Poulenc Rorer Sa Procede de production de proteines recombinantes et cellules hote utilisees.
FR2680518A1 (fr) * 1991-08-21 1993-02-26 Rhone Poulenc Rorer Sa Promoteur de levure et son utilisation.
ES2080689B1 (es) * 1994-04-21 1996-09-01 Urquima Sa Procedimiento de obtencion de un edulcorante natural proteico.
US6682924B1 (en) * 1995-05-05 2004-01-27 Novozymes A/S Protease variants and compositions
US5837517A (en) * 1995-05-05 1998-11-17 Novo Nordisk A/S Protease variants and compositions
GB9907461D0 (en) 1999-03-31 1999-05-26 King S College London Neurite regeneration
US6265186B1 (en) 1997-04-11 2001-07-24 Dsm N.V. Yeast cells comprising at least two copies of a desired gene integrated into the chromosomal genome at more than one non-ribosomal RNA encoding domain, particularly with Kluyveromyces
EP0973918B1 (de) * 1997-04-11 2008-06-11 DSM IP Assets B.V. Hefezellen welche zumindest zwei kopien von einem erwünschten gens enthalt und integrierte in dem chromosomal genom auf mehr als einem nicht-ribosomaler rns kodierende bereich, ins besonders mit kluyveromyces
ES2154995B1 (es) * 1998-11-20 2001-11-16 Consejo Superior Investigacion Levadura panadera recombinante capaz de asimilar lactosa.
US8372620B2 (en) 1998-12-23 2013-02-12 Dupont Nutrition Biosciences Aps Bacterial xylanases
BR0010806B1 (pt) * 1999-05-21 2014-02-18 Métodos e materiais para a síntese de produtos orgânicos
DE19943383B4 (de) * 1999-09-10 2006-03-16 Tad Pharma Gmbh Regulatorische Sequenzen und Expressionskassetten für Hefen
WO2002014509A1 (en) * 2000-08-10 2002-02-21 Ono Pharmaceutical Co., Ltd. Glycerylaldehyde-3-phosphate dehydrogenase promoter inducing cell death
GB0020498D0 (en) 2000-08-18 2000-10-11 Sterix Ltd Compound
US7141410B2 (en) * 2000-11-22 2006-11-28 Natureworks Llc Methods and materials for the production of organic products in cells of Candida species
JP2004521619A (ja) 2000-11-22 2004-07-22 カージル ダウ ポリマーズ エルエルシー 有機生成物の合成のための方法及び材料
EP1326957B1 (de) 2000-12-07 2004-05-06 DSM IP Assets B.V. Verfahren zur verhinderung oder verminderung der trübung in getränken
KR20030085112A (ko) 2000-12-07 2003-11-03 디에스엠 아이피 어셋츠 비.브이. 카르복시 말단 프롤린 잔기를 갖는 펩티드가 풍부한단백질 가수분해물
GB0116453D0 (en) 2001-07-05 2001-08-29 Imp College Innovations Ltd Method
EP2305312B1 (de) 2001-10-10 2015-03-04 ratiopharm GmbH Neumodulierung und Glykokonjugation von Follitropin (FSH)
US7517671B2 (en) 2002-02-28 2009-04-14 New England Biolabs, Inc. Methods and compositions for concentrating secreted recombinant protein
ES2525873T3 (es) 2002-06-07 2014-12-30 Dsm Ip Assets B.V. Método mejorado para la prevención o reducción del enturbiamiento en bebidas
TWI328612B (en) 2002-07-25 2010-08-11 Dsm Ip Assets Bv Genes and their encoded polypeptides involved in the biosynthetic pathway of vitamin b12, vectors and host cells comprising the genes, and process for producing vitamin b12
EP1615945B1 (de) 2003-04-09 2011-09-28 BioGeneriX AG Glycopegylierungsverfahren und durch die verfahren hergestellte proteine/peptide
GB0403864D0 (en) 2004-02-20 2004-03-24 Ucl Ventures Modulator
EP2439266B1 (de) 2005-11-28 2017-02-01 DSM IP Assets B.V. Enzympräparate zur Abgabe eines schlechten Geschmacks
GB0600406D0 (en) 2006-01-10 2006-02-15 Univ Bath Crystal
US8012733B2 (en) 2007-02-20 2011-09-06 Dsm Ip Assets B.V. Sialidases
BRPI0809248A2 (pt) 2007-03-22 2014-09-23 Dsm Ip Assests Bv Lisil oxidase
WO2011101339A2 (en) 2010-02-18 2011-08-25 Dsm Ip Assets B.V. Fermentation broth and filtration filter cake and uses thereof
WO2011105841A2 (ko) * 2010-02-24 2011-09-01 중앙대학교 산학협력단 브라제인 발현용 재조합 발현벡터 및 높은 단맛을 가지는 신규한 브라제인 다중 변이체
WO2012007445A1 (en) 2010-07-13 2012-01-19 Dsm Ip Assets B.V. Mutarotase in crystallization
WO2012007446A1 (en) 2010-07-13 2012-01-19 Dsm Ip Assets B.V. Use of a mutarotase in the production of dried powders

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4237224A (en) 1974-11-04 1980-12-02 Board Of Trustees Of The Leland Stanford Jr. University Process for producing biologically functional molecular chimeras
FR2441659A1 (fr) * 1978-11-14 1980-06-13 Anvar Nouveaux plasmides hybrides et microorganismes les contenant
IL63270A0 (en) * 1980-08-05 1981-10-30 Univ Leland Stanford Junior Eukaryotic autonomously replicating segment
IL63035A (en) * 1980-09-09 1985-05-31 Univ California Dnas capable of replication and stable mitotic maintenance in a host eukaryote,their preparation and eukaryotic cells comprising them
EP0066617A1 (de) * 1980-12-10 1982-12-15 Beckman Instruments, Inc. Leiten eines verdampften musters in metastabilem gas
DE3177281T2 (de) 1980-12-12 1992-12-10 Unilever Nv Strukturgene, die fuer die verschiedenen allelischen und reifungsformen von praeprothaumatin und deren mutanten kodieren, diese strukturgene enthaltende klonierungsvektoren und deren expression in mikrobiellen wirtzellen.
ATE22327T1 (de) * 1980-12-12 1986-10-15 Unilever Nv Dna-sequenzen fuer verschiedene allele formen des reifen thaumatins, diese sequenzen enthaltende rekombinante plasmide, verfahren zur herstellung dieser plasmide, diese rekombinante plasmide enthaltende bakterielle kulturen und verfahren zur herstellung von reifen thaumatin.
US4666847A (en) * 1981-01-16 1987-05-19 Collaborative Research, Inc. Recombinant DNA means and method
NZ199722A (en) * 1981-02-25 1985-12-13 Genentech Inc Dna transfer vector for expression of exogenous polypeptide in yeast;transformed yeast strain
JPS57146571A (en) * 1981-03-09 1982-09-10 Mitsubishi Chem Ind Ltd Killer yeast
DK368882A (da) * 1981-08-25 1983-02-26 Alan John Kingsman Expessions vektorer
BR8205954A (pt) 1981-10-14 1983-09-13 Unilever Nv Sequencia de dna,plasmidio recombinante,cultura bacteriana e microorganismos
IE55817B1 (en) * 1982-05-19 1991-01-30 Gist Brocades Nv Cloning system for kluyveromyces species

Also Published As

Publication number Publication date
DE3381090D1 (de) 1990-02-15
PT76727B (en) 1985-12-27
DK173699B1 (da) 2001-07-02
CA1224735A (en) 1987-07-28
WO1983004051A1 (en) 1983-11-24
GR78852B (de) 1984-10-02
WO1983004050A1 (en) 1983-11-24
AR241796A1 (es) 1992-12-30
ES522556A0 (es) 1984-03-01
JPS61275227A (ja) 1986-12-05
NO172397B (no) 1993-04-05
JPS59500848A (ja) 1984-05-17
IE55817B1 (en) 1991-01-30
FI81379B (fi) 1990-06-29
HU204097B (en) 1991-11-28
FI81379C (fi) 1990-10-10
NZ204302A (en) 1987-03-06
FI840149L (fi) 1984-01-16
DE3379665D1 (en) 1989-05-24
ATE49421T1 (de) 1990-01-15
DK11384A (da) 1984-01-11
JPH0543348B2 (de) 1993-07-01
EP0096430B2 (de) 1998-04-01
IE831185L (en) 1983-11-19
JPH0685720B2 (ja) 1994-11-02
US4657857A (en) 1987-04-14
AU571181B2 (en) 1988-04-14
PT76727A (en) 1983-06-01
FI840149A0 (fi) 1984-01-16
JP2608540B2 (ja) 1997-05-07
NO172397C (no) 1993-07-14
EP0096910B1 (de) 1989-04-19
IL68733A (en) 1989-01-31
DK11384D0 (da) 1984-01-11
US4859596A (en) 1989-08-22
AU1553983A (en) 1983-12-02
ES8402874A1 (es) 1984-03-01
JPS59501572A (ja) 1984-09-06
NO840133L (no) 1984-01-13
BR8307525A (pt) 1984-08-21
EP0096430B1 (de) 1990-01-10
EP0096910A1 (de) 1983-12-28
EP0096430A1 (de) 1983-12-21

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