ES8402874A1 - Procedimiento de obtencion de nuevas cepas de la levadura kluyveromyces. - Google Patents
Procedimiento de obtencion de nuevas cepas de la levadura kluyveromyces.Info
- Publication number
- ES8402874A1 ES8402874A1 ES522556A ES522556A ES8402874A1 ES 8402874 A1 ES8402874 A1 ES 8402874A1 ES 522556 A ES522556 A ES 522556A ES 522556 A ES522556 A ES 522556A ES 8402874 A1 ES8402874 A1 ES 8402874A1
- Authority
- ES
- Spain
- Prior art keywords
- forms
- yeast
- modified
- expression
- yeasts
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
- C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
- C12N9/2405—Glucanases
- C12N9/2408—Glucanases acting on alpha -1,4-glucosidic bonds
- C12N9/2411—Amylases
- C12N9/2428—Glucan 1,4-alpha-glucosidase (3.2.1.3), i.e. glucoamylase
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
- C07K14/43—Sweetening agents, e.g. thaumatin, monellin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/67—General methods for enhancing the expression
- C12N15/68—Stabilisation of the vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
- C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
- C12N15/815—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts for yeasts other than Saccharomyces
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
- C12N15/90—Stable introduction of foreign DNA into chromosome
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6478—Aspartic endopeptidases (3.4.23)
- C12N9/6481—Pepsins (3.4.23.1; 3.4.23.2; 3.4.23.3)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/036—Fusion polypeptide containing a localisation/targetting motif targeting to the medium outside of the cell, e.g. type III secretion
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Mycology (AREA)
- Plant Pathology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Botany (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pyrane Compounds (AREA)
- Enzymes And Modification Thereof (AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE NUEVAS CEPAS DE LA LEVADURA KLUYVEROMYCES.COMPRENDE LAS SIGUIENTES ETAPAS: PRIMERA, SE COMBINAN PROTOPLASTOS DE CELULAS DE LEVADURA PERTENECIENTES AL GENERO KLUYVEROMYCES) Y SE LES TRANSFORMA MEDIANTE MOLECULAS VECTOR QUE CONTIENEN AL MENOS UNA GEN CON UNA PROPIEDAD SELECTIVA; SEGUNDA, SE PERMITE LA REGENERACION DE LOS PROTOPLASTOS A CELULAS COMPLETAS CON UNA PARED CELULAR; Y POR ULTIMO, SE PERMITE EL CRECIMIENTO DE LAS CELULAS DE LEVADURA SOBRE UN MEDIO DE SELECCION, EN DONDE LAS CELULAS TRANSFORMADAS POR EL VECTOR PUEDEN DISTINGUIRSE POR MEDIODE LA PROPIEDAD SELECCIONABLE DE LAS OTRAS CELULAS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
NL8202091 | 1982-05-19 |
Publications (2)
Publication Number | Publication Date |
---|---|
ES8402874A1 true ES8402874A1 (es) | 1984-03-01 |
ES522556A0 ES522556A0 (es) | 1984-03-01 |
Family
ID=19839766
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES522556A Granted ES522556A0 (es) | 1982-05-19 | 1983-05-19 | Procedimiento de obtencion de nuevas cepas de la levadura kluyveromyces. |
Country Status (20)
Country | Link |
---|---|
US (2) | US4657857A (es) |
EP (2) | EP0096430B2 (es) |
JP (3) | JP2608540B2 (es) |
AR (1) | AR241796A1 (es) |
AT (2) | ATE49421T1 (es) |
AU (1) | AU571181B2 (es) |
BR (1) | BR8307525A (es) |
CA (1) | CA1224735A (es) |
DE (2) | DE3381090D1 (es) |
DK (1) | DK173699B1 (es) |
ES (1) | ES522556A0 (es) |
FI (1) | FI81379C (es) |
GR (1) | GR78852B (es) |
HU (1) | HU204097B (es) |
IE (1) | IE55817B1 (es) |
IL (1) | IL68733A (es) |
NO (1) | NO172397C (es) |
NZ (1) | NZ204302A (es) |
PT (1) | PT76727B (es) |
WO (2) | WO1983004050A1 (es) |
Families Citing this family (65)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS58146281A (ja) * | 1981-10-19 | 1983-08-31 | Suntory Ltd | 酵母細胞の形質転換法 |
US4943529A (en) | 1982-05-19 | 1990-07-24 | Gist-Brocades Nv | Kluyveromyces as a host strain |
PT76727B (en) * | 1982-05-19 | 1985-12-27 | Gist Brocades Nv | Process for the preparation of clones for kluyveromyces species |
JPH0716432B2 (ja) * | 1982-10-20 | 1995-03-01 | サントリー株式会社 | 酵母の高発現ベクタープラスミドを用いたペプチドの生産方法 |
CA1341116C (en) * | 1983-02-22 | 2000-10-17 | Rae Lyn Burke | Yeast expression systems with vectors having gapdh or pyk promoters and synthesis or foreign protein |
US4876197A (en) * | 1983-02-22 | 1989-10-24 | Chiron Corporation | Eukaryotic regulatable transcription |
EP0129268B1 (en) * | 1983-05-19 | 1989-10-04 | Unilever N.V. | Improvements in the expression of newly introduced genes in yeast cells |
AU577334B2 (en) * | 1983-10-11 | 1988-09-22 | International Genetic Engineering, Inc. | Synthetic thaumatin genes |
IL75210A0 (en) * | 1984-05-22 | 1985-09-29 | Bioteknika International | Yeast vector |
US6214577B1 (en) | 1984-05-22 | 2001-04-10 | Robert Rogers Yocum | Yeast vectors conferring antibiotic resistance |
US5422267A (en) * | 1984-05-22 | 1995-06-06 | Robert R. Yocum | Industrial yeast comprising an integrated glucoamylase gene |
US5741672A (en) * | 1984-07-27 | 1998-04-21 | Unilever Patent Holdings B.V. | Expression and production of polypeptides using the promoters of the hansenula polymorpha MOX and DAS genes |
US5240838A (en) * | 1984-07-27 | 1993-08-31 | Internationale Otrool Maatschappij "Octropa" B.V. | Regulatory sequences of alcohol oxidase (MOX) and dihydroxyacetonesynthase (DAS) of Hansenula polymorpha |
US4837148A (en) * | 1984-10-30 | 1989-06-06 | Phillips Petroleum Company | Autonomous replication sequences for yeast strains of the genus pichia |
US4879231A (en) * | 1984-10-30 | 1989-11-07 | Phillips Petroleum Company | Transformation of yeasts of the genus pichia |
US4855231A (en) * | 1984-10-30 | 1989-08-08 | Phillips Petroleum Company | Regulatory region for heterologous gene expression in yeast |
US5047340A (en) * | 1985-06-05 | 1991-09-10 | The University Of Kentucky Research Foundation | LAC+ saccharomyces cerevisiae |
CA1310923C (en) * | 1985-11-13 | 1992-12-01 | Joachim Ludwig Weickmann | Dna encoding [asp --] and [lys -, asp --] thaumatin i |
IT1203758B (it) * | 1986-03-27 | 1989-02-23 | Univ Roma | Vettori di clonazione e di espressione di geni eterologhi in lieviti e lieviti trasformati con tali vettori |
CA1339101C (en) * | 1986-06-03 | 1997-07-29 | Nicolaas Overbeeke | Production of guar alpha-galactosidase and immunologically related alpha-galactosidases by host organisms transformed with recombinant dna methods |
EP0257115A1 (en) * | 1986-08-21 | 1988-03-02 | Heineken Technisch Beheer B.V. | Amylolytic enzyme producing microorganisms, constructed by recombinant DNA technology, and their use in fermentation processes |
EP0260404B1 (en) * | 1986-08-21 | 1995-05-31 | VAN DEN BERG, Robert | Amylolytic enzymes producing microorganisms constructed by recombinant DNA technology and their use for fermentation processes |
US5151354A (en) * | 1986-08-21 | 1992-09-29 | Cornelius Hollenberg | Fermentation processes using amylolytic enzyme producing microorganisms |
US5882884A (en) * | 1987-06-19 | 1999-03-16 | Lucky Biotech Corporation | Expression of proteinaceous sweeteners in yeast |
PT88133B (pt) * | 1987-07-28 | 1995-03-01 | Gist Brocades Nv | Processo para a preparacao de polipeptideos por expressao em kluyveromyces |
FR2649991B2 (fr) | 1988-08-05 | 1994-03-04 | Rhone Poulenc Sante | Utilisation de derives stables du plasmide pkd1 pour l'expression et la secretion de proteines heterologues dans les levures du genre kluyveromyces |
US5221624A (en) * | 1988-11-08 | 1993-06-22 | International Genetic Engineering, Inc. | DNA encoding (Lys46, Asp97, Asp113) and (Lys46, Asp.sup.137) thaumatin I polypeptides |
US5204252A (en) * | 1989-02-08 | 1993-04-20 | Henkel Research Corporation | Candida tropicalis transformation system |
DE69033816T2 (de) | 1989-02-24 | 2002-08-08 | Monsanto Technology Llc | Synthetische pflanzengene und verfahren zu ihrer herstellung |
US20010003849A1 (en) | 1989-08-07 | 2001-06-14 | Kenneth A. Barton | Expression of genes in plants |
US5264554A (en) * | 1990-01-19 | 1993-11-23 | The Blood Center Of Southeastern Wisconsin, Inc. | Platelet cell adhesion molecule and variants thereof |
FR2678636A1 (fr) * | 1991-07-02 | 1993-01-08 | Rhone Poulenc Rorer Sa | Procede de production de proteines recombinantes et cellules hote utilisees. |
FR2680518A1 (fr) * | 1991-08-21 | 1993-02-26 | Rhone Poulenc Rorer Sa | Promoteur de levure et son utilisation. |
ES2080689B1 (es) * | 1994-04-21 | 1996-09-01 | Urquima Sa | Procedimiento de obtencion de un edulcorante natural proteico. |
US5837517A (en) * | 1995-05-05 | 1998-11-17 | Novo Nordisk A/S | Protease variants and compositions |
US6682924B1 (en) * | 1995-05-05 | 2004-01-27 | Novozymes A/S | Protease variants and compositions |
GB9907461D0 (en) | 1999-03-31 | 1999-05-26 | King S College London | Neurite regeneration |
US6265186B1 (en) | 1997-04-11 | 2001-07-24 | Dsm N.V. | Yeast cells comprising at least two copies of a desired gene integrated into the chromosomal genome at more than one non-ribosomal RNA encoding domain, particularly with Kluyveromyces |
AU8013798A (en) * | 1997-04-11 | 1998-11-11 | Gist-Brocades B.V. | Yeast cells comprising at least two copies of a desired gene integrated into thechromosomal genome at more than one non-ribosomal rna encoding domain, particul arly with kluyveromyces |
ES2154995B1 (es) * | 1998-11-20 | 2001-11-16 | Consejo Superior Investigacion | Levadura panadera recombinante capaz de asimilar lactosa. |
US8372620B2 (en) | 1998-12-23 | 2013-02-12 | Dupont Nutrition Biosciences Aps | Bacterial xylanases |
KR20020048910A (ko) | 1999-05-21 | 2002-06-24 | 카길 다우 엘엘씨 | 유기 생성물의 합성방법 및 재료 |
DE19943383B4 (de) | 1999-09-10 | 2006-03-16 | Tad Pharma Gmbh | Regulatorische Sequenzen und Expressionskassetten für Hefen |
JPWO2002014509A1 (ja) * | 2000-08-10 | 2004-01-15 | 小野薬品工業株式会社 | 細胞死を誘導するグリセルアルデヒド−3−リン酸デヒドロゲナーゼプロモータ |
GB0020498D0 (en) | 2000-08-18 | 2000-10-11 | Sterix Ltd | Compound |
CA2430270A1 (en) | 2000-11-22 | 2002-05-30 | Cargill Dow Polymers, Llc | Methods and materials for the synthesis of organic products |
US7141410B2 (en) | 2000-11-22 | 2006-11-28 | Natureworks Llc | Methods and materials for the production of organic products in cells of Candida species |
BR0115998B1 (pt) | 2000-12-07 | 2015-02-18 | Dsm Ip Assets Bv | Método para a prevenção ou redução de turvação em uma bebida, bem como bebidas obteníveis a partir de dito método. |
CA2430893C (en) | 2000-12-07 | 2013-07-30 | Dsm Ip Assets B.V. | Protein hydrolysates enriched in peptides having a carboxy terminal proline residue |
GB0116453D0 (en) | 2001-07-05 | 2001-08-29 | Imp College Innovations Ltd | Method |
SG159381A1 (en) | 2001-10-10 | 2010-03-30 | Novo Nordisk As | Remodeling and glycoconjugation of peptides |
DK2279755T3 (da) | 2001-10-10 | 2014-05-26 | Ratiopharm Gmbh | Remodellering og glycokonjugering af fibroblastvækstfaktor (FGF) |
US7517671B2 (en) | 2002-02-28 | 2009-04-14 | New England Biolabs, Inc. | Methods and compositions for concentrating secreted recombinant protein |
ES2525873T3 (es) | 2002-06-07 | 2014-12-30 | Dsm Ip Assets B.V. | Método mejorado para la prevención o reducción del enturbiamiento en bebidas |
TWI328612B (en) | 2002-07-25 | 2010-08-11 | Dsm Ip Assets Bv | Genes and their encoded polypeptides involved in the biosynthetic pathway of vitamin b12, vectors and host cells comprising the genes, and process for producing vitamin b12 |
MXPA05010773A (es) | 2003-04-09 | 2005-12-12 | Neose Technologies Inc | Metodos de glicopegilacion y proteinas/peptidos producidos por los metodos. |
GB0403864D0 (en) | 2004-02-20 | 2004-03-24 | Ucl Ventures | Modulator |
NZ713149A (en) | 2005-11-28 | 2017-02-24 | Dsm Ip Assets Bv | Enzyme preparations yielding a clean taste |
GB0600406D0 (en) | 2006-01-10 | 2006-02-15 | Univ Bath | Crystal |
ES2492469T3 (es) | 2007-02-20 | 2014-09-09 | Dsm Ip Assets B.V. | Nueva sialidasa |
EP2126060B1 (en) | 2007-03-22 | 2016-10-05 | DSM IP Assets B.V. | Novel lysyl oxidases |
WO2011101339A2 (en) | 2010-02-18 | 2011-08-25 | Dsm Ip Assets B.V. | Fermentation broth and filtration filter cake and uses thereof |
WO2011105841A2 (ko) * | 2010-02-24 | 2011-09-01 | 중앙대학교 산학협력단 | 브라제인 발현용 재조합 발현벡터 및 높은 단맛을 가지는 신규한 브라제인 다중 변이체 |
WO2012007446A1 (en) | 2010-07-13 | 2012-01-19 | Dsm Ip Assets B.V. | Use of a mutarotase in the production of dried powders |
WO2012007445A1 (en) | 2010-07-13 | 2012-01-19 | Dsm Ip Assets B.V. | Mutarotase in crystallization |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4237224A (en) | 1974-11-04 | 1980-12-02 | Board Of Trustees Of The Leland Stanford Jr. University | Process for producing biologically functional molecular chimeras |
FR2441659A1 (fr) * | 1978-11-14 | 1980-06-13 | Anvar | Nouveaux plasmides hybrides et microorganismes les contenant |
IL63270A0 (en) * | 1980-08-05 | 1981-10-30 | Univ Leland Stanford Junior | Eukaryotic autonomously replicating segment |
IL63035A (en) * | 1980-09-09 | 1985-05-31 | Univ California | Dnas capable of replication and stable mitotic maintenance in a host eukaryote,their preparation and eukaryotic cells comprising them |
EP0066617A1 (en) * | 1980-12-10 | 1982-12-15 | Beckman Instruments, Inc. | Entraining vaporized sample in metastable gas |
EP0054330B1 (en) * | 1980-12-12 | 1986-09-17 | Unilever N.V. | Dna sequences encoding various allelic forms of mature thaumatin, recombinant plasmids comprising said dna's and a process for their preparation, bacterial cultures comprising said recombinant plasmids, and method for producing mature thaumatin |
BR8108073A (pt) * | 1980-12-12 | 1982-09-21 | Unilever Nv | Sequencias de dna;plasmidios recombinantes;cultura bacteriana;e processo para a producao de preprotaumatina,pretaumatina ou protaumatina |
US4666847A (en) * | 1981-01-16 | 1987-05-19 | Collaborative Research, Inc. | Recombinant DNA means and method |
NZ199722A (en) * | 1981-02-25 | 1985-12-13 | Genentech Inc | Dna transfer vector for expression of exogenous polypeptide in yeast;transformed yeast strain |
JPS57146571A (en) * | 1981-03-09 | 1982-09-10 | Mitsubishi Chem Ind Ltd | Killer yeast |
IE54046B1 (en) * | 1981-08-25 | 1989-05-24 | Celltech Ltd | Expression vectors |
BR8205954A (pt) | 1981-10-14 | 1983-09-13 | Unilever Nv | Sequencia de dna,plasmidio recombinante,cultura bacteriana e microorganismos |
PT76727B (en) * | 1982-05-19 | 1985-12-27 | Gist Brocades Nv | Process for the preparation of clones for kluyveromyces species |
-
1983
- 1983-05-19 PT PT76727A patent/PT76727B/pt unknown
- 1983-05-19 WO PCT/EP1983/000128 patent/WO1983004050A1/en active IP Right Grant
- 1983-05-19 AT AT83200714T patent/ATE49421T1/de not_active IP Right Cessation
- 1983-05-19 IL IL68733A patent/IL68733A/xx unknown
- 1983-05-19 CA CA000428497A patent/CA1224735A/en not_active Expired
- 1983-05-19 AR AR83293108A patent/AR241796A1/es active
- 1983-05-19 HU HU832272A patent/HU204097B/hu not_active IP Right Cessation
- 1983-05-19 IE IE1185/83A patent/IE55817B1/en not_active IP Right Cessation
- 1983-05-19 GR GR71403A patent/GR78852B/el unknown
- 1983-05-19 EP EP83200714A patent/EP0096430B2/en not_active Expired - Lifetime
- 1983-05-19 ES ES522556A patent/ES522556A0/es active Granted
- 1983-05-19 EP EP83200712A patent/EP0096910B1/en not_active Expired
- 1983-05-19 JP JP58501749A patent/JP2608540B2/ja not_active Expired - Lifetime
- 1983-05-19 JP JP58501746A patent/JPS59501572A/ja active Granted
- 1983-05-19 WO PCT/EP1983/000129 patent/WO1983004051A1/en unknown
- 1983-05-19 AT AT83200712T patent/ATE42338T1/de not_active IP Right Cessation
- 1983-05-19 AU AU15539/83A patent/AU571181B2/en not_active Expired
- 1983-05-19 DE DE8383200714T patent/DE3381090D1/de not_active Expired - Lifetime
- 1983-05-19 US US06/570,984 patent/US4657857A/en not_active Expired - Fee Related
- 1983-05-19 BR BR8307525A patent/BR8307525A/pt unknown
- 1983-05-19 DE DE8383200712T patent/DE3379665D1/de not_active Expired
- 1983-05-20 NZ NZ204302A patent/NZ204302A/en unknown
-
1984
- 1984-01-11 DK DK198400113A patent/DK173699B1/da not_active IP Right Cessation
- 1984-01-13 NO NO84840133A patent/NO172397C/no not_active IP Right Cessation
- 1984-01-16 FI FI840149A patent/FI81379C/fi not_active IP Right Cessation
- 1984-01-19 US US06/572,414 patent/US4859596A/en not_active Expired - Lifetime
-
1986
- 1986-02-26 JP JP61041331A patent/JPH0685720B2/ja not_active Expired - Lifetime
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ES8402874A1 (es) | Procedimiento de obtencion de nuevas cepas de la levadura kluyveromyces. | |
EP0370458A3 (en) | Synthetic DNA derived recombinant HIV-1 antigens | |
WO2000020555A3 (en) | Transformation system in the field of filamentous fungal hosts: in chrysosporium | |
EP0088195A3 (en) | Messenger rna, production and use thereof | |
FI794001A (fi) | Recombinat-dna-molekyler och metod foer produktion daerav | |
ES2006941A6 (es) | Un metodo de producir un peptido o una proteina relacionados con un epitope de virus asociado a linfoadenopatiasnvirus de leucemia de celulas t humanas (lavnhtlv-iii). | |
CA2015077A1 (en) | A yeast cell of the genus schwanniomyces | |
ES8308361A1 (es) | Un metodo para la produccion de un polipeptido. | |
AU4875785A (en) | Autonomous dna replication sequence from pichia yeast | |
WO1999032617A3 (en) | Expression cloning in filamentous fungi | |
EP0123289A3 (en) | A-factor and its processing signals | |
DK0505311T3 (da) | Fremstilling til fremstilling af hemproteiner | |
JPS536491A (en) | Frothing compositon | |
CA2089753A1 (en) | Interleukin-2-leukotoxin gene fusions and uses therefor | |
WO1991011515A3 (en) | Leukocyte-derived growth factor | |
ES8706824A1 (es) | Un metodo para preparar proteinas que son inmunologicamente reactivas con anticuerpos para virus asociados con linfadenopatia. | |
WO2005035779A3 (en) | Method | |
GB8616219D0 (en) | Monoclonal antibodies | |
WO2001081582A3 (en) | Isolation and characterization of the csa operon (etec-cs4 pili) and methods of using same | |
DK0396436T3 (da) | Gærstammer til fremstilling af modne heterologe proteiner, især hirudin | |
RU94046052A (ru) | Гены агглютинации, дрожжи | |
EP0114759A3 (en) | Amino acid sequences and polypeptides including these sequences and having the specificity of foot and mouth disease and other viral antigens | |
DK0463024T3 (da) | DNA-konstruktion og modificeret gær | |
MY104405A (en) | Structural gene comprising dna coding for an endotoxin protein having toxic activity against insects. | |
ES8706825A1 (es) | Un procedimiento para preparar un plasmido recombinante |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PC1A | Transfer granted |