NO323104B1 - Analoger av humant erytropoietin, DNA-sekvenser som koder for disse, eukaryot vertscelle transfektert med DNA-sekvensene, preparat som omfatter analogene, anvendelse av analogene til okning av hematokritt, og fremgangsmate for fremstilling av analogene. - Google Patents
Analoger av humant erytropoietin, DNA-sekvenser som koder for disse, eukaryot vertscelle transfektert med DNA-sekvensene, preparat som omfatter analogene, anvendelse av analogene til okning av hematokritt, og fremgangsmate for fremstilling av analogene. Download PDFInfo
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- NO323104B1 NO323104B1 NO19951445A NO951445A NO323104B1 NO 323104 B1 NO323104 B1 NO 323104B1 NO 19951445 A NO19951445 A NO 19951445A NO 951445 A NO951445 A NO 951445A NO 323104 B1 NO323104 B1 NO 323104B1
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- erythropoietin
- analogue
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/505—Erythropoietin [EPO]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Toxicology (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Fruits And Vegetables (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Plant Substances (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10801693A | 1993-08-17 | 1993-08-17 | |
PCT/US1994/009257 WO1995005465A1 (en) | 1993-08-17 | 1994-08-16 | Erythropoietin analogs |
Publications (3)
Publication Number | Publication Date |
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NO951445D0 NO951445D0 (no) | 1995-04-12 |
NO951445L NO951445L (no) | 1995-06-16 |
NO323104B1 true NO323104B1 (no) | 2007-01-02 |
Family
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Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO19951445A NO323104B1 (no) | 1993-08-17 | 1995-04-12 | Analoger av humant erytropoietin, DNA-sekvenser som koder for disse, eukaryot vertscelle transfektert med DNA-sekvensene, preparat som omfatter analogene, anvendelse av analogene til okning av hematokritt, og fremgangsmate for fremstilling av analogene. |
NO2007008C NO2007008I2 (no) | 1993-08-17 | 2007-06-29 | Analoger av humant erytropoietin,DNA-sekvenser somkoder for disse, eukaryot vertscelle transfektert med DNA-sekvensene, preparat som omfatter analoge ne, anvendelse av analogene til økning av hematokritt, og fremgangsmåte for fremstilling av analogene. |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
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NO2007008C NO2007008I2 (no) | 1993-08-17 | 2007-06-29 | Analoger av humant erytropoietin,DNA-sekvenser somkoder for disse, eukaryot vertscelle transfektert med DNA-sekvensene, preparat som omfatter analoge ne, anvendelse av analogene til økning av hematokritt, og fremgangsmåte for fremstilling av analogene. |
Country Status (27)
Country | Link |
---|---|
EP (1) | EP0640619B2 (de) |
JP (3) | JP2938572B2 (de) |
KR (2) | KR100328769B1 (de) |
CN (1) | CN1057534C (de) |
AT (1) | ATE155796T1 (de) |
AU (1) | AU677097B2 (de) |
CA (1) | CA2147124C (de) |
CZ (3) | CZ291229B6 (de) |
DE (2) | DE69404401T3 (de) |
DK (1) | DK0640619T4 (de) |
ES (1) | ES2105442T5 (de) |
FI (1) | FI117136B (de) |
GR (1) | GR3024815T3 (de) |
HK (1) | HK1001589A1 (de) |
HU (1) | HU220334B (de) |
IL (4) | IL110669A (de) |
LU (1) | LU90850I2 (de) |
LV (1) | LV10972B (de) |
NL (1) | NL300075I2 (de) |
NO (2) | NO323104B1 (de) |
NZ (1) | NZ273134A (de) |
RU (1) | RU2159814C2 (de) |
SI (1) | SI0640619T2 (de) |
SK (1) | SK282003B6 (de) |
UA (1) | UA49793C2 (de) |
WO (1) | WO1995005465A1 (de) |
ZA (1) | ZA946122B (de) |
Families Citing this family (234)
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US7217689B1 (en) | 1989-10-13 | 2007-05-15 | Amgen Inc. | Glycosylation analogs of erythropoietin |
US5614184A (en) * | 1992-07-28 | 1997-03-25 | New England Deaconess Hospital | Recombinant human erythropoietin mutants and therapeutic methods employing them |
US5989538A (en) * | 1995-02-15 | 1999-11-23 | Amgen Inc. | Mpl ligand analogs |
US5696250A (en) * | 1995-02-15 | 1997-12-09 | Amgen Inc. | DNA encoding megakaryocyte growth and development factor analogs |
EP0854882A1 (de) * | 1995-10-09 | 1998-07-29 | PHARMACIA & UPJOHN COMPANY | Polypeptid-akzeptor für n-acetylgalactosaminyltransferase |
KR100400637B1 (ko) * | 1996-02-06 | 2004-03-10 | 씨제이 주식회사 | 생물학적으로유용한펩타이드 |
AU719482B2 (en) | 1996-03-14 | 2000-05-11 | Genentech Inc. | Uses of GDNF and GDNF receptor |
US5952226A (en) * | 1996-11-05 | 1999-09-14 | Modex Therapeutiques | Hypoxia responsive EPO producing cells |
ES2208798T3 (es) * | 1997-09-01 | 2004-06-16 | Aventis Pharma Deutschland Gmbh | Eritropoyetina humana recombinante con un perfil de glicosilacion ventajoso. |
JP4336452B2 (ja) | 1997-12-08 | 2009-09-30 | メルク パテント ゲーエムベーハー | 標的化免疫治療および一般の免疫刺激に対して有用である二量体融合タンパク質 |
AU775422B2 (en) | 1998-06-15 | 2004-07-29 | Gtc Biotherapeutics, Inc. | Erythropoietin analog-human serum albumin fusion |
KR20010075661A (ko) * | 1998-10-23 | 2001-08-09 | 스티븐 엠. 오드레 | 빈혈 예방 및 치료 방법과 이를 위한 조성물 |
US7304150B1 (en) | 1998-10-23 | 2007-12-04 | Amgen Inc. | Methods and compositions for the prevention and treatment of anemia |
DE19857609A1 (de) | 1998-12-14 | 2000-06-15 | Hannelore Ehrenreich | Verwendung von Erythropoietin zur Behandlung von cerebralen Ischämien des Menschen |
PT1151102E (pt) * | 1999-02-12 | 2006-07-31 | Amgen Inc | Composicoes de leptina glicosilada e metodos afins |
US7410941B1 (en) | 1999-04-13 | 2008-08-12 | The Kenneth S. Warren Institute, Inc. | Methods for treatment of neurodegenerative conditions by peripherally administered erythropoietin |
US7345019B1 (en) | 1999-04-13 | 2008-03-18 | The Kenneth S. Warren Institute, Inc. | Modulation of excitable tissue function by peripherally administered erythropoietin |
US8236561B2 (en) | 1999-04-15 | 2012-08-07 | Crucell Holland B.V. | Efficient production of IgA in recombinant mammalian cells |
US6855544B1 (en) | 1999-04-15 | 2005-02-15 | Crucell Holland B.V. | Recombinant protein production in a human cell |
US7297680B2 (en) | 1999-04-15 | 2007-11-20 | Crucell Holland B.V. | Compositions of erythropoietin isoforms comprising Lewis-X structures and high sialic acid content |
US7604960B2 (en) | 1999-04-15 | 2009-10-20 | Crucell Holland B.V. | Transient protein expression methods |
EP1177285A1 (de) * | 1999-05-07 | 2002-02-06 | Genentech, Inc. | Erythropoietinpolypeptide und dafür kodierende nukleinsäuren von schimpansen |
US6831060B2 (en) | 1999-05-07 | 2004-12-14 | Genentech, Inc. | Chimpanzee erythropoietin (CHEPO) polypeptides and nucleic acids encoding the same |
US6555343B1 (en) | 1999-05-07 | 2003-04-29 | Genentech Inc. | Chimpanzee erythropoietin (CHEPO) polypeptides and nucleic acids encoding the same |
PE20010288A1 (es) * | 1999-07-02 | 2001-03-07 | Hoffmann La Roche | Derivados de eritropoyetina |
CZ299516B6 (cs) * | 1999-07-02 | 2008-08-20 | F. Hoffmann-La Roche Ag | Konjugát erythropoetinového glykoproteinu, zpusobjeho výroby a použití a farmaceutická kompozice sjeho obsahem |
SK782002A3 (en) | 1999-07-21 | 2003-08-05 | Lexigen Pharm Corp | FC fusion proteins for enhancing the immunogenicity of protein and peptide antigens |
CA2391080A1 (en) * | 1999-11-12 | 2001-05-25 | Merck Patent Gesellschaft Mit Beschraenkter Haftung | Erythropoietin forms with improved properties |
US7192759B1 (en) | 1999-11-26 | 2007-03-20 | Crucell Holland B.V. | Production of vaccines |
US7521220B2 (en) | 1999-11-26 | 2009-04-21 | Crucell Holland B.V. | Production of vaccines |
US7527961B2 (en) | 1999-11-26 | 2009-05-05 | Crucell Holland B.V. | Production of vaccines |
DK1252192T3 (da) | 2000-02-11 | 2006-11-20 | Merck Patent Gmbh | Forbedring af antistofbaserede fusionsproteiners serumhalveringstid |
US6586398B1 (en) * | 2000-04-07 | 2003-07-01 | Amgen, Inc. | Chemically modified novel erythropoietin stimulating protein compositions and methods |
SI1274728T1 (sl) * | 2000-04-21 | 2008-08-31 | Amgen Inc | Postopek in sestavki za prepreäśevanje in/ali zdravljenje anemije |
DK1311285T4 (en) * | 2000-05-15 | 2017-07-24 | Hoffmann La Roche | Liquid pharmaceutical composition containing an erythropoietin derivative |
US7259146B2 (en) | 2000-05-26 | 2007-08-21 | Ortho-Mcneil Pharmaceutical, Inc. | Neuroprotective peptides |
WO2002011753A1 (fr) | 2000-08-04 | 2002-02-14 | Chugai Seiyaku Kabushiki Kaisha | Preparations proteiniques a injecter |
ES2477996T3 (es) | 2000-08-11 | 2014-07-18 | Chugai Seiyaku Kabushiki Kaisha | Preparaciones estabilizadas que contienen un anticuerpo |
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