US4294846A
(en)
*
|
1979-09-21 |
1981-10-13 |
Merck & Co., Inc. |
Hypocholesteremic fermentation products and products of preparation
|
AU548996B2
(en)
|
1980-02-04 |
1986-01-09 |
Merck & Co., Inc. |
Tetrahydro-2h-pyran-2-one derivatives
|
US4282155A
(en)
*
|
1980-02-04 |
1981-08-04 |
Merck & Co., Inc. |
Antihypercholesterolemic compounds
|
US4444784A
(en)
*
|
1980-08-05 |
1984-04-24 |
Merck & Co., Inc. |
Antihypercholesterolemic compounds
|
US4293496A
(en)
*
|
1980-02-04 |
1981-10-06 |
Merck & Co., Inc. |
6(R)-[2-(8-Hydroxy-2,6-dimethylpolyhydronaphthyl-1)-ethyl]-4(R)-hydroxy-3,4,5,6-tetrahydro-2H-pyran-2-ones
|
US4351844A
(en)
*
|
1980-02-04 |
1982-09-28 |
Merck & Co., Inc. |
Hypocholesterolemic hydrogenation products and process of preparation
|
PT72394B
(en)
*
|
1980-02-04 |
1982-09-06 |
Merck & Co Inc |
Process for preparing dihydro and tetrahydromevinoline hypocholesterolimics
|
JPH0692381B2
(ja)
*
|
1980-03-31 |
1994-11-16 |
三共株式会社 |
Mb−530a誘導体
|
JPS56150037A
(en)
*
|
1980-04-22 |
1981-11-20 |
Sankyo Co Ltd |
Hydronaphthalene compound
|
US4420491A
(en)
*
|
1980-05-28 |
1983-12-13 |
Merck & Co., Inc. |
Hypocholesteremic fermentation products and process of preparation
|
US4450171A
(en)
*
|
1980-08-05 |
1984-05-22 |
Merck & Co., Inc. |
Antihypercholesterolemic compounds
|
US4432996A
(en)
*
|
1980-11-17 |
1984-02-21 |
Merck & Co., Inc. |
Hypocholesterolemic fermentation products and process of preparation
|
US4343814A
(en)
*
|
1980-11-17 |
1982-08-10 |
Merck & Co., Inc. |
Hypocholesterolemic fermentation products
|
JPS57144279A
(en)
*
|
1981-03-02 |
1982-09-06 |
Sankyo Co Ltd |
Dihydro ml-236b and dihydro mb-530b and derivative thereof
|
US4376863A
(en)
*
|
1981-08-21 |
1983-03-15 |
Merck & Co., Inc. |
Hypocholesterolemic fermentation products
|
US4387242A
(en)
*
|
1981-08-21 |
1983-06-07 |
Merck & Co., Inc. |
Hypocholesterolemic fermentation products and process of preparation
|
US4503072A
(en)
*
|
1982-12-22 |
1985-03-05 |
Merck & Co., Inc. |
Antihypercholesterolemic compounds
|
US4582915A
(en)
*
|
1983-10-11 |
1986-04-15 |
Merck & Co., Inc. |
Process for C-methylation of 2-methylbutyrates
|
US4584389A
(en)
*
|
1983-10-11 |
1986-04-22 |
Merck & Co., Inc. |
Processes for preparing 6(R)-[2-[8(S)(2,2-dimethylbutyryloxy)-2(S),6(S)-dimethyl-1,2,3,4,4a(S),5,6,7,8,8a(S)-decahydronaphthyl-1(S)]ethyl]-4(R)-hydroxy-3,4,5,6-tetrahydro-2H-pyran-2-one
|
US4950775A
(en)
*
|
1985-10-11 |
1990-08-21 |
University Of California |
Antihypercholesterolemic compounds and synthesis thereof
|
US5208258A
(en)
*
|
1985-10-11 |
1993-05-04 |
The Regents Of The University Of California |
Antihypercholesterolemic compounds and synthesis thereof
|
US4738982A
(en)
*
|
1986-04-28 |
1988-04-19 |
Merck & Co., Inc. |
HMG-CoA reductase inhibitors
|
US5116870A
(en)
*
|
1986-06-23 |
1992-05-26 |
Merck & Co., Inc. |
HMG-CoA reductase inhibitors
|
US4940727A
(en)
*
|
1986-06-23 |
1990-07-10 |
Merck & Co., Inc. |
Novel HMG-CoA reductase inhibitors
|
USRE36481E
(en)
*
|
1986-06-23 |
2000-01-04 |
Merck & Co., Inc. |
HMG-CoA reductase inhibitors
|
JPS6334525U
(no)
*
|
1986-08-26 |
1988-03-05 |
|
|
US4678806A
(en)
*
|
1986-09-02 |
1987-07-07 |
Merck & Co., Inc. |
Prodrugs of antihypercholesterolemic compounds
|
US4845237A
(en)
*
|
1987-04-15 |
1989-07-04 |
Merck & Co., Inc. |
Acylation process for the synthesis of HMG-CoA reductase inhibitors
|
US4719229A
(en)
*
|
1987-05-13 |
1988-01-12 |
Merck & Co., Inc. |
Antihypercholesterolemic agents
|
US4782084A
(en)
*
|
1987-06-29 |
1988-11-01 |
Merck & Co., Inc. |
HMG-COA reductase inhibitors
|
DE3739882A1
(de)
*
|
1987-11-25 |
1989-06-08 |
Bayer Ag |
Substituierte hydroxylamine
|
US5595734A
(en)
*
|
1988-04-06 |
1997-01-21 |
Alfacell Corporation |
Compositions comprising ONCONASE (tm) and lovastatin
|
US5075327A
(en)
*
|
1988-08-10 |
1991-12-24 |
Hoffmann-La Roche Inc. |
Antipsoriatic agents
|
JPH0251582A
(ja)
*
|
1988-08-12 |
1990-02-21 |
Kyokado Eng Co Ltd |
地盤注入用薬液
|
PT91878B
(pt)
*
|
1988-10-03 |
1995-05-31 |
Glaxo Group Ltd |
Processo para a preparacao de derivados do imidazole com propriedades hipocolesterolemicas e hipolipidemicas
|
US5021451A
(en)
*
|
1988-11-14 |
1991-06-04 |
Hoffman-La Roche Inc. |
Method for inhibiting hyperproliferative diseases
|
US5073568A
(en)
*
|
1988-11-14 |
1991-12-17 |
Hoffmann-La Roche Inc. |
Antipsoriatic agents
|
US5200549A
(en)
*
|
1988-11-14 |
1993-04-06 |
Hoffman-La Roche Inc. |
Antipsoriatic agents
|
US5376383A
(en)
*
|
1988-11-21 |
1994-12-27 |
Merck & Co., Inc. |
Method for enhancing the lowering of plasma-cholesterol levels
|
US5260305A
(en)
*
|
1988-12-12 |
1993-11-09 |
E. R. Squibb & Sons, Inc. |
Combination of pravastatin and nicotinic acid or related acid and method for lowering serum cholesterol using such combination
|
AU618158B2
(en)
*
|
1989-01-07 |
1991-12-12 |
Bayer Aktiengesellschaft |
New substituted pyrido(2,3-d)pyrimidines
|
US5166364A
(en)
*
|
1989-02-27 |
1992-11-24 |
E. R. Squibb & Sons, Inc. |
Mevinic acid derivatives useful as antihypercholesterolemic agents and method for preparing same
|
JPH02229630A
(ja)
*
|
1989-03-01 |
1990-09-12 |
Kyodo Kumiai F I T |
金型
|
JPH02148727U
(no)
*
|
1989-04-27 |
1990-12-18 |
|
|
CA2016467A1
(en)
|
1989-06-05 |
1990-12-05 |
Martin Eisman |
Method for treating peripheral atherosclerotic disease employing an hmg coa reductase inhibitor and/or a squalene synthetase inhibitor
|
US5001148A
(en)
*
|
1989-06-07 |
1991-03-19 |
E. R. Squibb & Sons, Inc. |
Mevinic acid derivatives
|
US5145959A
(en)
*
|
1989-07-18 |
1992-09-08 |
Bayer Aktiengesellschaft |
Substituted pyrido (2,3-d) pyrimidines as intermediates
|
FI94339C
(fi)
|
1989-07-21 |
1995-08-25 |
Warner Lambert Co |
Menetelmä farmaseuttisesti käyttökelpoisen /R-(R*,R*)/-2-(4-fluorifenyyli)- , -dihydroksi-5-(1-metyylietyyli)-3-fenyyli-4-/(fenyyliamino)karbonyyli/-1H-pyrroli-1-heptaanihapon ja sen farmaseuttisesti hyväksyttävien suolojen valmistamiseksi
|
US4970221A
(en)
*
|
1989-07-28 |
1990-11-13 |
E. R. Squibb & Sons, Inc. |
3,5-dihydroxypentanoic acid derivatives useful as antihypercholesterolemic agents and method for preparing same
|
DE3929507A1
(de)
*
|
1989-09-06 |
1991-03-07 |
Bayer Ag |
Substituierte amino-pyridine
|
US5316765A
(en)
*
|
1989-09-07 |
1994-05-31 |
Karl Folkers Foundation For Biomedical And Clinical Research |
Use of coenzyme Q10 in combination with HMG-CoA reductase inhibitor therapies
|
US5173487A
(en)
*
|
1989-11-13 |
1992-12-22 |
E. R. Squibb & Sons, Inc. |
Mevinic acid derivatives
|
US5264455A
(en)
*
|
1990-07-06 |
1993-11-23 |
E. R. Squibb & Sons, Inc. |
Sulfur-substituted mevinic acid derivatives
|
US5223415A
(en)
*
|
1990-10-15 |
1993-06-29 |
Merck & Co., Inc. |
Biosynthetic production of 7-[1',2',6',7',8',8a'(R)-hexahydro-2'(S),6'(R)-dimethyl-8'(S)-hydroxy-1'(S)-naphthyl]-3(R),5(R)-dihydroxyheptanoic acid (triol acid)
|
US5177080A
(en)
|
1990-12-14 |
1993-01-05 |
Bayer Aktiengesellschaft |
Substituted pyridyl-dihydroxy-heptenoic acid and its salts
|
US5288928A
(en)
*
|
1990-12-21 |
1994-02-22 |
Ciba-Geigy Corporation |
Asymmetrical hydrogenation
|
US5202029A
(en)
*
|
1991-03-13 |
1993-04-13 |
Caron Kabushiki Kaisha |
Process for purification of hmg-coa reductase inhibitors
|
US5151365A
(en)
*
|
1991-03-18 |
1992-09-29 |
Merck & Co., Inc. |
Culture of Asperigillus versicolor and mutants thereof
|
US5250435A
(en)
*
|
1991-06-04 |
1993-10-05 |
Merck & Co., Inc. |
Mutant strains of Aspergillus terreus for producing 7-[1,2,6,7,8,8a(R)-hexa-hydro-2(S),6(R)-dimethyl-8(S)-hydroxy-1(S)-naphthyl]-3(R),5(R)-dihydroxyheptanoic acid (triol acid),I)
|
US5364948A
(en)
*
|
1991-08-02 |
1994-11-15 |
Merck & Co., Inc. |
Biologically active compounds isolated from aerobic fermentation of Trichoderma viride
|
EP0526936A3
(en)
*
|
1991-08-02 |
1993-05-05 |
Merck & Co. Inc. |
Cholesterol-lowering agents
|
US5286746A
(en)
*
|
1991-12-20 |
1994-02-15 |
E. R. Squibb & Sons, Inc. |
Sulfur-substituted mevinic acid derivatives
|
HU208997B
(en)
*
|
1992-06-17 |
1994-02-28 |
Gyogyszerkutato Intezet |
Microbiological method for producing mevinoline
|
JP3233476B2
(ja)
*
|
1992-10-22 |
2001-11-26 |
社団法人北里研究所 |
Fo−1289物質およびその製造法
|
DE4243279A1
(de)
*
|
1992-12-21 |
1994-06-23 |
Bayer Ag |
Substituierte Triole
|
DE4244029A1
(de)
*
|
1992-12-24 |
1994-06-30 |
Bayer Ag |
Neue substituierte Pyridine
|
US6190894B1
(en)
|
1993-03-19 |
2001-02-20 |
The Regents Of The University Of California |
Method and compositions for disrupting the epithelial barrier function
|
SI9300303A
(en)
*
|
1993-06-08 |
1994-12-31 |
Krka Tovarna Zdravil |
Process for isolation of hypolipemic effective substance
|
US5409820A
(en)
*
|
1993-08-06 |
1995-04-25 |
Apotex, Inc. |
Process for the production of lovastatin using Coniothyrium fuckelii
|
EP0726940A4
(en)
|
1993-11-02 |
2001-05-23 |
Merck & Co Inc |
DNA ENCODING A TRIOL-POLYCETIDE-SYNTHASE
|
WO1995013063A1
(en)
*
|
1993-11-09 |
1995-05-18 |
Merck & Co., Inc. |
HMG-CoA REDUCTASE INHIBITORS IN THE NORMALIZATION OF VASCULAR ENDOTHELIAL DYSFUNCTION
|
US5730992A
(en)
*
|
1994-09-13 |
1998-03-24 |
Ramot University Authority For Applied Research And Industrial Development, Ltd. |
Compositions for the treatment of skin disorders
|
US6268392B1
(en)
|
1994-09-13 |
2001-07-31 |
G. D. Searle & Co. |
Combination therapy employing ileal bile acid transport inhibiting benzothiepines and HMG Co-A reductase inhibitors
|
US6642268B2
(en)
|
1994-09-13 |
2003-11-04 |
G.D. Searle & Co. |
Combination therapy employing ileal bile acid transport inhibiting benzothipines and HMG Co-A reductase inhibitors
|
US6262277B1
(en)
*
|
1994-09-13 |
2001-07-17 |
G.D. Searle And Company |
Intermediates and processes for the preparation of benzothiepines having activity as inhibitors of ileal bile acid transport and taurocholate uptake
|
IL110943A
(en)
*
|
1994-09-13 |
1997-02-18 |
Univ Ramot |
Compositions comprising an inhibitor of cholesterol synthesis for the treatment of skin disorders
|
IL115420A0
(en)
|
1994-09-26 |
1995-12-31 |
Zeneca Ltd |
Aminoheterocyclic derivatives
|
US20110196039A9
(en)
*
|
1994-10-05 |
2011-08-11 |
Kaesemeyer Wayne H |
Controlled release arginine formulations
|
US5674488A
(en)
*
|
1994-10-07 |
1997-10-07 |
Reich; John J. |
Method for prevention and treatment of hyperchlolesterolemia by in vivo hydrogenation of cholesterol
|
US5616595A
(en)
*
|
1995-06-07 |
1997-04-01 |
Abbott Laboratories |
Process for recovering water insoluble compounds from a fermentation broth
|
GB9602166D0
(en)
*
|
1996-02-02 |
1996-04-03 |
Zeneca Ltd |
Aminoheterocyclic derivatives
|
WO1997028128A1
(en)
|
1996-02-02 |
1997-08-07 |
Zeneca Limited |
Heterocyclic compounds useful as pharmaceutical agents
|
US5763653A
(en)
*
|
1997-03-13 |
1998-06-09 |
Ranbaxy Laboratories, Ltd. |
Key intermediates in the manufacture of simvastatin
|
DE19627420A1
(de)
*
|
1996-07-08 |
1998-01-15 |
Bayer Ag |
6-(Hydroxymethyl-ethyl)pyridine
|
WO1998006705A1
(en)
*
|
1996-08-14 |
1998-02-19 |
Zeneca Limited |
Substituted pyrimidine derivatives and their pharmaceutical use
|
US7238348B2
(en)
*
|
1996-09-30 |
2007-07-03 |
Beijing Peking University Wbl Corporation Ltd. |
Method of treatment of osteoporosis with compositions of red rice fermentation products
|
US6046022A
(en)
*
|
1996-09-30 |
2000-04-04 |
Peking University |
Methods and compositions employing red rice fermentation products
|
UA56197C2
(uk)
|
1996-11-08 |
2003-05-15 |
Зенека Лімітед |
Гетероциклічні похідні
|
US5763646A
(en)
*
|
1997-03-13 |
1998-06-09 |
Ranbaxy Laboratories, Ltd. |
Process for manufacturing simvastatin from lovastatin or mevinolinic acid
|
WO1998035956A1
(en)
|
1997-02-13 |
1998-08-20 |
Zeneca Limited |
Heterocyclic compounds useful as oxido-squalene cyclase inhibitors
|
WO1998035959A1
(en)
|
1997-02-13 |
1998-08-20 |
Zeneca Limited |
Heterocyclic compounds useful as oxido-squalene cyclase inhibitors
|
ATE327340T1
(de)
*
|
1997-02-20 |
2006-06-15 |
Dsm Ip Assets Bv |
Fermentative herstellung von wertstoffen in industriellem umfang durch verwendung von chemisch definierten media
|
EP0877089A1
(en)
|
1997-05-07 |
1998-11-11 |
Gist-Brocades B.V. |
HMG-CoA reductase inhibitor preparation process
|
GB9715895D0
(en)
|
1997-07-29 |
1997-10-01 |
Zeneca Ltd |
Heterocyclic compounds
|
US20010006644A1
(en)
|
1997-07-31 |
2001-07-05 |
David J. Bova |
Combinations of hmg-coa reductase inhibitors and nicotinic acid and methods for treating hyperlipidemia once a day at night
|
KR100234976B1
(ko)
*
|
1997-08-01 |
1999-12-15 |
김충환 |
세룰레닌 및 엘-메치오닌 유사체에 동시 내성을 갖는 아스퍼질 러스속 미생물 및 그를 이용한 메비놀린산의 제조방법
|
GT199800127A
(es)
|
1997-08-29 |
2000-02-01 |
|
Combinaciones terapeuticas.
|
US6177121B1
(en)
|
1997-09-29 |
2001-01-23 |
Purdue Research Foundation |
Composition and method for producing low cholesterol eggs
|
US6147109A
(en)
*
|
1997-10-14 |
2000-11-14 |
The General Hospital Corporation |
Upregulation of Type III endothelial cell Nitric Oxide Synthase by HMG-CoA reductase inhibitors
|
US6083497A
(en)
*
|
1997-11-05 |
2000-07-04 |
Geltex Pharmaceuticals, Inc. |
Method for treating hypercholesterolemia with unsubstituted polydiallylamine polymers
|
US20080275104A1
(en)
*
|
1997-11-25 |
2008-11-06 |
Musc Foundation For Research Development |
Methods of treating juvenile type 1 diabetes mellitus
|
US20040029962A1
(en)
*
|
1997-12-12 |
2004-02-12 |
Chih-Ming Chen |
HMG-COA reductase inhibitor extended release formulation
|
US8679534B2
(en)
*
|
1997-12-12 |
2014-03-25 |
Andrx Labs, Llc |
HMG-CoA reductase inhibitor extended release formulation
|
US6180597B1
(en)
|
1998-03-19 |
2001-01-30 |
Brigham And Women's Hospital, Inc. |
Upregulation of Type III endothelial cell nitric oxide synthase by rho GTPase function inhibitors
|
US20030078211A1
(en)
*
|
1998-06-24 |
2003-04-24 |
Merck & Co., Inc. |
Compositions and methods for inhibiting bone resorption
|
EP1088333A4
(en)
|
1998-06-24 |
2005-08-10 |
Merck & Co Inc |
METHOD AND COMPOSITIONS FOR CONNECTING OSTEOPROSIS
|
US6423751B1
(en)
|
1998-07-14 |
2002-07-23 |
The Brigham And Women's Hospital, Inc. |
Upregulation of type III endothelial cell nitric oxide synthase by agents that disrupt actin cytoskeletal organization
|
US5985907A
(en)
*
|
1998-08-12 |
1999-11-16 |
Health Research, Inc. |
Method for inhibiting growth of methanogens
|
IL141786A0
(en)
|
1998-09-17 |
2002-03-10 |
Bristol Myers Squibb Co |
A pharmaceutical composition for treating diabetes containing an ap2 inhibitor
|
SI20072A
(sl)
|
1998-09-18 |
2000-04-30 |
LEK, tovarna farmacevtskih in kemi�nih izdelkov, d.d. |
Postopek za pridobivanje inhibitorjev HMG-CoA reduktaze
|
US7141602B2
(en)
*
|
1998-09-18 |
2006-11-28 |
Lek Pharmaceuticals D.D. |
Process for obtaining HMG-CoA reductase inhibitors of high purity
|
US20080213378A1
(en)
*
|
1998-10-01 |
2008-09-04 |
Elan Pharma International, Ltd. |
Nanoparticulate statin formulations and novel statin combinations
|
SK288117B6
(sk)
|
1998-11-20 |
2013-09-03 |
Skyepharma Canada Inc. |
Rapidly dispersing solid dry therapeutic dosage form
|
US6391583B1
(en)
|
1998-12-18 |
2002-05-21 |
Wisconsin Alumni Research Foundation |
Method of producing antihypercholesterolemic agents
|
NZ512534A
(en)
|
1998-12-23 |
2003-11-28 |
G |
Combinations of cholesteryl ester transfer protein inhibitors and fibric acid derivatives for cardiovascular indications
|
DK1140190T3
(da)
|
1998-12-23 |
2002-12-23 |
Searle Llc |
Kombinationer af ileumgaldesyretransport-inhibitorer og galdesyre-sekvestreringsmidler til cardiovaskulære indikatorer
|
EP1140184B1
(en)
*
|
1998-12-23 |
2003-06-04 |
G.D. Searle LLC. |
Combinations of cholesteryl ester transfer protein inhibitors and nicotinic acid derivatives for cardiovascular indications
|
NZ512537A
(en)
|
1998-12-23 |
2003-11-28 |
G |
Combinations of ileal bile acid transport inhibitors and fibric acid derivatives for cardiovascular indications
|
PT1140185E
(pt)
|
1998-12-23 |
2003-10-31 |
Searle Llc |
Combinacoes de inibidores de proteina de transferencia de ester de colesterilo com agentes sequestrantes de acido biliar para indicacoes cardiovasculares
|
WO2000038722A1
(en)
|
1998-12-23 |
2000-07-06 |
G.D. Searle & Co. |
COMBINATIONS OF CHOLESTERYL ESTER TRANSFER PROTEIN INHIBITORS AND HMG CoA REDUCTASE INHIBITORS FOR CARDIOVASCULAR INDICATIONS
|
BR9916486A
(pt)
*
|
1998-12-23 |
2002-02-05 |
Searle Llc |
Combinações de inibidores do transporte de ácidos biliares no ìleo e inibidores da proteìna de transferência do ester colesteril para indicações cardiovasculares
|
IL143944A0
(en)
*
|
1998-12-23 |
2002-04-21 |
Searle Llc |
Combinations for cardiovascular indications
|
US6323021B1
(en)
|
1999-01-15 |
2001-11-27 |
Industrial Technology Research Institute |
Mutant strain of penicillium citrinum and use thereof for preparation of compactin
|
GB9902989D0
(en)
|
1999-02-11 |
1999-03-31 |
Zeneca Ltd |
Heterocyclic derivatives
|
US6569461B1
(en)
|
1999-03-08 |
2003-05-27 |
Merck & Co., Inc. |
Dihydroxy open-acid and salts of HMG-CoA reductase inhibitors
|
SE9903028D0
(sv)
*
|
1999-08-27 |
1999-08-27 |
Astra Ab |
New use
|
WO2001015674A2
(en)
*
|
1999-08-30 |
2001-03-08 |
Aventis Pharma Deutschland Gmbh |
Use of inhibitors of the renin-angiotensin system in the prevention of cardiovascular events
|
EP1216037A2
(en)
*
|
1999-09-21 |
2002-06-26 |
Emory University |
Methods and compositions for treating platelet-related disorders using mpl pathway inhibitory agents
|
US6372462B2
(en)
|
1999-10-15 |
2002-04-16 |
Medmyco Ltd. |
Process for producing, methods and compositions of cholesterol lowering agents from higher basidiomycetes mushrooms
|
EP1228057A2
(en)
|
1999-10-27 |
2002-08-07 |
Merck & Co., Inc. |
Lactonization process
|
KR100342789B1
(ko)
|
1999-10-29 |
2002-07-04 |
김용규 |
니스타틴에 내성을 갖는 아스퍼질러스속 미생물 및 그를 이용한 트리올 헵타노익산의 제조방법
|
JP2003523330A
(ja)
|
2000-02-04 |
2003-08-05 |
チルドレンズ・ホスピタル・リサーチ・ファウンデイション |
アテローム性動脈硬化症および関連疾患のための脂質加水分解治療
|
WO2001068096A2
(en)
*
|
2000-03-10 |
2001-09-20 |
Pharmacia Corporation |
Combination therapy for the prophylaxis and treatment of hyperlipidemic conditions and disorders
|
US6395767B2
(en)
|
2000-03-10 |
2002-05-28 |
Bristol-Myers Squibb Company |
Cyclopropyl-fused pyrrolidine-based inhibitors of dipeptidyl peptidase IV and method
|
WO2001068637A2
(en)
|
2000-03-10 |
2001-09-20 |
Pharmacia Corporation |
Method for the preparation of tetrahydrobenzothiepines
|
DE10030375A1
(de)
*
|
2000-06-21 |
2002-01-03 |
Bayer Ag |
Verwendung von MTP-Inhibitoren zur Senkung von ppTRL
|
IN192861B
(no)
|
2000-06-30 |
2004-05-22 |
Ranbaxy Lab Ltd |
|
EP1314425A4
(en)
*
|
2000-08-30 |
2004-06-02 |
Sankyo Co |
MEDICINAL COMPOSITIONS FOR THE PREVENTION OR TREATMENT OF HEART FAILURE
|
JO2654B1
(en)
*
|
2000-09-04 |
2012-06-17 |
شركة جانسين فارماسوتيكا ان. في |
Multiple aryl caroxa amides are useful as lipid - lowering agents
|
US8586094B2
(en)
|
2000-09-20 |
2013-11-19 |
Jagotec Ag |
Coated tablets
|
JP3737801B2
(ja)
*
|
2000-10-05 |
2006-01-25 |
テバ ジョジセルジャール レースベニュタールシャシャーグ |
プラバスタチンラクトン及びエピプラバスタチンを実質的に含まないプラバスタチンナトリウム、並びにそれを含む組成物
|
US6534540B2
(en)
|
2000-10-06 |
2003-03-18 |
George Kindness |
Combination and method of treatment of cancer utilizing a COX-2 inhibitor and a 3-hydroxy-3-methylglutaryl-coenzyme-a (HMG-CoA) reductase inhibitor
|
US20030162829A1
(en)
*
|
2000-10-06 |
2003-08-28 |
George Kindness |
Combination of treatment of cancer utilizing a COX-2 inhibitor and a 3-hydroxy-3-methylglutaryl-coenzyme-a (HMG-CoA) reductase inhibitor
|
SK4112003A3
(en)
*
|
2000-10-12 |
2004-01-08 |
Nissan Chemical Ind Ltd |
Preventives and remedies for complications of diabetes
|
US6777552B2
(en)
|
2001-08-16 |
2004-08-17 |
Teva Pharmaceutical Industries, Ltd. |
Processes for preparing calcium salt forms of statins
|
JO2409B1
(en)
*
|
2000-11-21 |
2007-06-17 |
شركة جانسين فارماسوتيكا ان. في |
Second-phenyl carboxy amides are useful as lipid-lowering agents
|
JO2390B1
(en)
*
|
2001-04-06 |
2007-06-17 |
شركة جانسين فارماسوتيكا ان. في |
Diphenylcarboxamides act as lipid-lowering agents
|
ATE318272T1
(de)
|
2001-04-11 |
2006-03-15 |
Bristol Myers Squibb Co |
Aminosäurekomplexe von c-arylglycosiden zur behandlung von diabetes und verfahren
|
EP2172204A1
(en)
*
|
2001-04-18 |
2010-04-07 |
Genzyme Corporation |
Methods of treating syndrome X with apliphatic polyamines
|
WO2002096416A1
(en)
*
|
2001-05-31 |
2002-12-05 |
Cellegy Pharmaceuticals, Inc. |
Store operated calcium influx inhibitors and methods of use
|
US20040077625A1
(en)
*
|
2001-07-25 |
2004-04-22 |
Tremont Samuel J. |
Novel 1,4-benzothiazepine and 1,5-benzothiazepine compounds as inhibitors of apical sodium codependent bile acid transport abd taurocholate uptake
|
US20040092565A1
(en)
*
|
2001-07-25 |
2004-05-13 |
George Kindness |
Composition and method of sustaining chemotherapeutic effect while reducing dose of chemotherapeutic agent using cox-2 inhibitor and statin
|
US7238671B2
(en)
*
|
2001-10-18 |
2007-07-03 |
Bristol-Myers Squibb Company |
Human glucagon-like-peptide-1 mimics and their use in the treatment of diabetes and related conditions
|
KR20040054729A
(ko)
*
|
2001-10-18 |
2004-06-25 |
브리스톨-마이어스 스큅 컴퍼니 |
인간 글루카곤-유사-펩티드-1 모방체, 및 당뇨병 및 이와관련된 증상의 치료에 있어서 이의 용도
|
US6806381B2
(en)
*
|
2001-11-02 |
2004-10-19 |
Bristol-Myers Squibb Company |
Process for the preparation of aniline-derived thyroid receptor ligands
|
JP2005518347A
(ja)
*
|
2001-11-02 |
2005-06-23 |
ジー.ディー. サール エルエルシー |
頂端ナトリウム共依存性胆汁酸輸送(asbt)およびタウロコール酸塩取り込みの阻害剤としての新規一および二フッ化ベンゾチエピン化合物
|
KR20050044352A
(ko)
*
|
2001-11-09 |
2005-05-12 |
아테로제닉스, 인코포레이티드 |
심혈관 병리의 역전 및 예방 방법
|
EP1443919A4
(en)
*
|
2001-11-16 |
2006-03-22 |
Bristol Myers Squibb Co |
DOUBLE INHIBITORS OF THE FATTY ACID BINDING PROTEIN OF THE ADIPOCYTES AND THE FATTY ACID BINDING PROTEIN OF KERATINOCYTES
|
US6831102B2
(en)
*
|
2001-12-07 |
2004-12-14 |
Bristol-Myers Squibb Company |
Phenyl naphthol ligands for thyroid hormone receptor
|
CA2469435A1
(en)
|
2001-12-21 |
2003-07-24 |
X-Ceptor Therapeutics, Inc. |
Modulators of lxr
|
US7482366B2
(en)
|
2001-12-21 |
2009-01-27 |
X-Ceptor Therapeutics, Inc. |
Modulators of LXR
|
ATE521599T1
(de)
*
|
2001-12-21 |
2011-09-15 |
X Ceptor Therapeutics Inc |
Heterocyclische modulatoren von nukleären rezeptoren
|
CA2471639A1
(en)
|
2002-01-17 |
2003-07-31 |
Pharmacia Corporation |
Novel alkyl/aryl hydroxy or keto thiepines.
|
EP2266590A3
(en)
|
2002-02-22 |
2011-04-20 |
Shire LLC |
Active agent delivery sytems and methods for protecting and administering active agents
|
KR100379075B1
(en)
*
|
2002-03-07 |
2003-04-08 |
Jinis Biopharmaceuticals Co |
Method for producing low cholesterol animal food product and food product therefrom
|
WO2003086395A1
(en)
|
2002-04-12 |
2003-10-23 |
Merck & Co., Inc. |
Tyrosine kinase inhibitors
|
AU2003226051A1
(en)
*
|
2002-04-16 |
2003-11-03 |
Banyu Pharmaceutical Co., Ltd. |
Solid forms of salts with tyrosine kinase activity
|
WO2003094845A2
(en)
|
2002-05-08 |
2003-11-20 |
Bristol-Myers Squibb Company |
Pyridine-based thyroid receptor ligands
|
CN102533972B
(zh)
|
2002-05-09 |
2014-07-02 |
布赖汉姆妇女医院 |
作为心血管病的标志和治疗靶的1l1rl-1
|
JP4478563B2
(ja)
*
|
2002-05-14 |
2010-06-09 |
プレゼント インヴェストメンツ エルエルシー |
送信信号の形成方法
|
US7057046B2
(en)
*
|
2002-05-20 |
2006-06-06 |
Bristol-Myers Squibb Company |
Lactam glycogen phosphorylase inhibitors and method of use
|
US7763278B2
(en)
*
|
2002-06-10 |
2010-07-27 |
Elan Pharma International Ltd. |
Nanoparticulate polycosanol formulations and novel polycosanol combinations
|
US20050182106A1
(en)
*
|
2002-07-11 |
2005-08-18 |
Sankyo Company, Limited |
Medicinal composition for mitigating blood lipid or lowering blood homocysteine
|
AU2003254354A1
(en)
*
|
2002-07-23 |
2004-02-09 |
Nutrinova Nutrition Specialties & Food Ingredients Gmbh |
Cholesterol-reducing agent made of dietary fibre and cholesterol-reducing substances
|
US20050182036A1
(en)
*
|
2002-08-02 |
2005-08-18 |
Sankyo Company, Limited |
Medicinal composition containing an HMG-CoA reductase inhibitor
|
US20050187204A1
(en)
*
|
2002-08-08 |
2005-08-25 |
Sankyo Company, Limited |
Medicinal composition for lowering blood lipid level
|
UA79300C2
(en)
*
|
2002-08-12 |
2007-06-11 |
Janssen Pharmaceutica Nv |
N-aryl piperidine substituted biphenylcarboxamides as inhibitors of apolipoprotein b secretion
|
US20080293750A1
(en)
*
|
2002-10-17 |
2008-11-27 |
Anna Helgadottir |
Susceptibility Gene for Myocardial Infarction, Stroke, Paod and Methods of Treatment
|
US20060019269A1
(en)
*
|
2002-10-17 |
2006-01-26 |
Decode Genetics, Inc. |
Susceptibility gene for myocardial infarction, stroke, and PAOD, methods of treatment
|
ES2344057T3
(es)
*
|
2002-10-23 |
2010-08-17 |
Bristol-Myers Squibb Company |
Inhibidores de la dipeptidil peptidasa iv basados en nitrilos de glicina.
|
WO2004037203A2
(en)
*
|
2002-10-24 |
2004-05-06 |
Enos Pharmaceuticals, Inc. |
Sustained release l-arginine formulations and methods of manufacture and use
|
US20080145424A1
(en)
*
|
2002-10-24 |
2008-06-19 |
Enos Phramaceuticals, Inc. |
Sustained release L-arginine formulations and methods of manufacture and use
|
US7098235B2
(en)
*
|
2002-11-14 |
2006-08-29 |
Bristol-Myers Squibb Co. |
Triglyceride and triglyceride-like prodrugs of glycogen phosphorylase inhibiting compounds
|
US20040110241A1
(en)
*
|
2002-12-06 |
2004-06-10 |
Segal Mark S. |
Materials and methods for monitoring vascular endothelial function
|
US20040198800A1
(en)
*
|
2002-12-19 |
2004-10-07 |
Geoffrey Allan |
Lipoxygenase inhibitors as hypolipidemic and anti-hypertensive agents
|
US20040132771A1
(en)
*
|
2002-12-20 |
2004-07-08 |
Pfizer Inc |
Compositions of choleseteryl ester transfer protein inhibitors and HMG-CoA reductase inhibitors
|
JP2006513186A
(ja)
|
2002-12-20 |
2006-04-20 |
ファイザー・プロダクツ・インク |
Cetp阻害剤およびhmg−coaレダクターゼ阻害剤を含む剤形
|
CA2510320C
(en)
*
|
2002-12-20 |
2012-10-09 |
St. James Associates Llc/Faber Research Series |
Coated particles for sustained-release pharmaceutical administration
|
DE10261067A1
(de)
*
|
2002-12-24 |
2004-08-05 |
Nutrinova Nutrition Specialties & Food Ingredients Gmbh |
Cholesterinsenkendes Mittel, enthaltend eine n-3-Fettsäure
|
DE10261061A1
(de)
*
|
2002-12-24 |
2004-07-15 |
Nutrinova Nutrition Specialties & Food Ingredients Gmbh |
Diätetisches Lebensmittel zur positiven Beeinflussung der kardiovaskulären Gesundheit
|
JP2006516620A
(ja)
*
|
2003-01-24 |
2006-07-06 |
ブリストル−マイヤーズ スクイブ カンパニー |
甲状腺受容体におけるシクロアルキル含有アニリドリガンド
|
TW200504021A
(en)
*
|
2003-01-24 |
2005-02-01 |
Bristol Myers Squibb Co |
Substituted anilide ligands for the thyroid receptor
|
US7557143B2
(en)
*
|
2003-04-18 |
2009-07-07 |
Bristol-Myers Squibb Company |
Thyroid receptor ligands
|
WO2004096276A1
(ja)
*
|
2003-04-28 |
2004-11-11 |
Sankyo Company, Limited |
糖取り込み能増強剤
|
US9345671B2
(en)
*
|
2003-04-28 |
2016-05-24 |
Daiichi Sankyo Company, Limited |
Adiponectin production enhancer
|
US7459474B2
(en)
*
|
2003-06-11 |
2008-12-02 |
Bristol-Myers Squibb Company |
Modulators of the glucocorticoid receptor and method
|
US7368468B2
(en)
*
|
2003-06-18 |
2008-05-06 |
Teva Pharmaceutical Industries Ltd. |
Fluvastatin sodium crystal forms XIV, LXXIII, LXXIX, LXXX and LXXXVII, processes for preparing them, compositions containing them and methods of using them
|
JP2007524619A
(ja)
*
|
2003-06-18 |
2007-08-30 |
テバ ファーマシューティカル インダストリーズ リミティド |
フルバスタチンナトリウム結晶型、その調製方法、これを含有する組成物、およびその使用法
|
JP2007531697A
(ja)
*
|
2003-07-11 |
2007-11-08 |
プロ−ファーマシューティカルズ,インコーポレイティド |
疎水性薬剤のデリバリーのための組成物と方法
|
US6995183B2
(en)
*
|
2003-08-01 |
2006-02-07 |
Bristol Myers Squibb Company |
Adamantylglycine-based inhibitors of dipeptidyl peptidase IV and methods
|
CN1839114A
(zh)
|
2003-08-21 |
2006-09-27 |
默克弗罗斯特加拿大有限公司 |
组织蛋白酶半胱氨酸蛋白酶抑制剂
|
EP1510208A1
(en)
*
|
2003-08-22 |
2005-03-02 |
Fournier Laboratories Ireland Limited |
Pharmaceutical composition comprising a combination of metformin and statin
|
EP1562912A2
(en)
*
|
2003-08-28 |
2005-08-17 |
Teva Pharmaceutical Industries Limited |
Process for preparation of rosuvastatin calcium
|
US20050053664A1
(en)
*
|
2003-09-08 |
2005-03-10 |
Eliezer Zomer |
Co-administration of a polysaccharide with a chemotherapeutic agent for the treatment of cancer
|
US20050171207A1
(en)
*
|
2003-09-26 |
2005-08-04 |
Myriad Genetics, Incorporated |
Method and composition for combination treatment of neurodegenerative disorders
|
JP2007521324A
(ja)
*
|
2003-09-29 |
2007-08-02 |
エノス ファーマシューティカルズ, インク. |
徐放性l−アルギニン調合物並びにその製造法及び使用法
|
US8227434B1
(en)
|
2003-11-04 |
2012-07-24 |
H. Lee Moffitt Cancer Center & Research Institute, Inc. |
Materials and methods for treating oncological disorders
|
ATE428411T1
(de)
*
|
2003-11-07 |
2009-05-15 |
Jj Pharma Inc |
Hdl-verstärkende kombinationstherapie-komplexe
|
US7767828B2
(en)
*
|
2003-11-12 |
2010-08-03 |
Phenomix Corporation |
Methyl and ethyl substituted pyrrolidine compounds and methods for selective inhibition of dipeptidyl peptidase-IV
|
US7317109B2
(en)
*
|
2003-11-12 |
2008-01-08 |
Phenomix Corporation |
Pyrrolidine compounds and methods for selective inhibition of dipeptidyl peptidase-IV
|
US7576121B2
(en)
*
|
2003-11-12 |
2009-08-18 |
Phenomix Corporation |
Pyrrolidine compounds and methods for selective inhibition of dipeptidyl peptidase-IV
|
WO2005047297A1
(en)
*
|
2003-11-12 |
2005-05-26 |
Phenomix Corporation |
Heterocyclic boronic acid compounds
|
WO2005051298A2
(en)
|
2003-11-19 |
2005-06-09 |
Metabasis Therapeutics, Inc. |
Novel phosphorus-containing thyromimetics
|
CA2546701C
(en)
*
|
2003-11-24 |
2010-07-27 |
Teva Pharmaceutical Industries Ltd. |
Crystalline ammonium salts of rosuvastatin
|
EP1722780A4
(en)
*
|
2003-11-26 |
2008-12-17 |
Univ Duke |
METHOD FOR PREVENTING OR TREATING GLAUCOMA
|
KR100887264B1
(ko)
*
|
2003-12-02 |
2009-03-06 |
테바 파마슈티컬 인더스트리즈 리미티드 |
로수바스타틴의 특성화를 위한 기준 표준물
|
WO2005058316A1
(ja)
*
|
2003-12-17 |
2005-06-30 |
Dainippon Sumitomo Pharma Co., Ltd. |
合剤および併用剤
|
US20050159615A1
(en)
*
|
2003-12-24 |
2005-07-21 |
Entire Interest. |
Process for preparation of statins with high syn to anti ratio
|
US7851624B2
(en)
*
|
2003-12-24 |
2010-12-14 |
Teva Pharamaceutical Industries Ltd. |
Triol form of rosuvastatin and synthesis of rosuvastatin
|
US20070179166A1
(en)
*
|
2003-12-24 |
2007-08-02 |
Valerie Niddam-Hildesheim |
Process for preparation of statins with high syn to anti ratio
|
US20070161700A1
(en)
*
|
2004-12-28 |
2007-07-12 |
Kowa Company, Ltd. |
Inhibitor for the formation of y-secretase complex
|
US8158362B2
(en)
*
|
2005-03-30 |
2012-04-17 |
Decode Genetics Ehf. |
Methods of diagnosing susceptibility to myocardial infarction and screening for an LTA4H haplotype
|
US20100216863A1
(en)
*
|
2004-01-30 |
2010-08-26 |
Decode Genetics Ehf. |
Susceptibility Gene for Myocardial Infarction, Stroke, and PAOD; Methods of Treatment
|
EP1563837A1
(en)
*
|
2004-02-03 |
2005-08-17 |
Ferrer Internacional, S.A. |
Hypocholesterolemic compositions comprising a statin and an antiflatulent agent
|
WO2005079314A2
(en)
*
|
2004-02-13 |
2005-09-01 |
Pro-Pharmaceuticals, Inc. |
Compositions and methods used to treat acne and candida
|
WO2005079846A1
(ja)
*
|
2004-02-25 |
2005-09-01 |
Kowa Company, Ltd. |
Racタンパク質の核内移行促進剤及びそのスクリーニング方法
|
JP4728226B2
(ja)
|
2004-02-25 |
2011-07-20 |
興和株式会社 |
Cdc42タンパク質の核内移行促進剤及びそのスクリーニング方法
|
WO2005087234A1
(en)
|
2004-03-05 |
2005-09-22 |
The Trustees Of The University Of Pennsylvania |
Methods for treating disorders or diseases associated with hyperlipidemia and hypercholesterolemia while minimizing side-effects
|
US7262318B2
(en)
*
|
2004-03-10 |
2007-08-28 |
Pfizer, Inc. |
Substituted heteroaryl- and phenylsulfamoyl compounds
|
US20060211752A1
(en)
|
2004-03-16 |
2006-09-21 |
Kohn Leonard D |
Use of phenylmethimazoles, methimazole derivatives, and tautomeric cyclic thiones for the treatment of autoimmune/inflammatory diseases associated with toll-like receptor overexpression
|
EP1734819A1
(en)
*
|
2004-03-19 |
2006-12-27 |
Pro-Pharmaceuticals, Inc. |
Compositions and methods for targeting metastatic tumors using multivalent ligand-linked carbohydrate polymers
|
AU2004317826A1
(en)
*
|
2004-03-30 |
2005-10-13 |
Lupin Ltd |
An improved method for manufacture of 4-hydroxy pyran-2-one derivatives
|
KR100598326B1
(ko)
|
2004-04-10 |
2006-07-10 |
한미약품 주식회사 |
HMG-CoA 환원효소 억제제의 경구투여용 서방형 제제및 이의 제조방법
|
CA2568542A1
(en)
*
|
2004-05-27 |
2005-12-08 |
Dexcel Pharma Technologies Ltd. |
Localized controlled absorption of statins in the gastrointestinal tract for achieving high blood levels of statins
|
US7803838B2
(en)
*
|
2004-06-04 |
2010-09-28 |
Forest Laboratories Holdings Limited |
Compositions comprising nebivolol
|
US20050288340A1
(en)
*
|
2004-06-29 |
2005-12-29 |
Pfizer Inc |
Substituted heteroaryl- and phenylsulfamoyl compounds
|
US7534763B2
(en)
|
2004-07-02 |
2009-05-19 |
Bristol-Myers Squibb Company |
Sustained release GLP-1 receptor modulators
|
TW200611704A
(en)
*
|
2004-07-02 |
2006-04-16 |
Bristol Myers Squibb Co |
Human glucagon-like-peptide-1 modulators and their use in the treatment of diabetes and related conditions
|
US7145040B2
(en)
*
|
2004-07-02 |
2006-12-05 |
Bristol-Myers Squibb Co. |
Process for the preparation of amino acids useful in the preparation of peptide receptor modulators
|
US7786163B2
(en)
*
|
2004-07-12 |
2010-08-31 |
Forest Laboratories Holdings Limited (BM) |
Constrained cyano compounds
|
US7179916B2
(en)
*
|
2004-07-13 |
2007-02-20 |
Teva Pharmaceutical Industries Ltd. |
Process for the preparation of rosuvastatin
|
US7572805B2
(en)
|
2004-07-14 |
2009-08-11 |
Bristol-Myers Squibb Company |
Pyrrolo(oxo)isoquinolines as 5HT ligands
|
US20110217412A1
(en)
*
|
2004-07-30 |
2011-09-08 |
Jinis Biopharmaceuticals Co. |
Cholesterol lowering supplement and low cholesterol egg produced by using the same
|
KR100637762B1
(ko)
*
|
2004-07-30 |
2006-10-23 |
주식회사 지니스 |
저콜레스테롤 란을 생산하기 위한 가금류용 사료첨가제 및 이를 이용한 저콜레스테롤 란의 생산방법
|
EP1773128A2
(en)
*
|
2004-08-02 |
2007-04-18 |
Pro-Pharmaceuticals, Inc. |
Compositions and methods for the enhancement of chemotherapy with microbial cytotoxins
|
US20090042979A1
(en)
*
|
2004-08-06 |
2009-02-12 |
Transform Pharmaceuticals Inc. |
Novel Statin Pharmaceutical Compositions and Related Methods of Treatment
|
JP2008509154A
(ja)
*
|
2004-08-06 |
2008-03-27 |
トランスフオーム・フアーマシユーチカルズ・インコーポレーテツド |
新規なスタチン薬剤組成物および関連治療方法
|
NZ552390A
(en)
*
|
2004-08-06 |
2010-01-29 |
Transform Pharmaceuticals Inc |
Novel fenofibrate formulations and related methods of treatment
|
US20060058261A1
(en)
*
|
2004-09-15 |
2006-03-16 |
Andre Aube |
Chitin derivatives for hyperlipidemia
|
AR051446A1
(es)
*
|
2004-09-23 |
2007-01-17 |
Bristol Myers Squibb Co |
Glucosidos de c-arilo como inhibidores selectivos de transportadores de glucosa (sglt2)
|
CA2624601C
(en)
|
2004-10-06 |
2018-07-03 |
The Brigham And Women's Hospital, Inc. |
Relevance of achieved levels of markers of systemic inflammation following treatment
|
US7517991B2
(en)
*
|
2004-10-12 |
2009-04-14 |
Bristol-Myers Squibb Company |
N-sulfonylpiperidine cannabinoid receptor 1 antagonists
|
CA2584740A1
(en)
*
|
2004-10-19 |
2006-04-27 |
Cargill, Incorporated |
Meat systems
|
KR101021828B1
(ko)
*
|
2004-10-27 |
2011-03-17 |
다이이찌 산쿄 가부시키가이샤 |
2 이상의 치환기를 갖는 벤젠 화합물
|
US20090196889A1
(en)
*
|
2004-11-22 |
2009-08-06 |
Dexcel Pharma Technologies Ltd. |
Controlled absorption of statins in the intestine
|
WO2006062876A2
(en)
|
2004-12-09 |
2006-06-15 |
Merck & Co., Inc. |
Estrogen receptor modulators
|
JP2008524159A
(ja)
*
|
2004-12-15 |
2008-07-10 |
ゾルファイ ファーマスーティカルズ ゲゼルシャフト ミット ベシュレンクテル ハフツング |
NEP阻害剤、内因性エンドセリン産生系の阻害剤およびHMGCoAレダクターゼ阻害剤を含有する医薬組成物
|
US7635699B2
(en)
*
|
2004-12-29 |
2009-12-22 |
Bristol-Myers Squibb Company |
Azolopyrimidine-based inhibitors of dipeptidyl peptidase IV and methods
|
US7589088B2
(en)
*
|
2004-12-29 |
2009-09-15 |
Bristol-Myers Squibb Company |
Pyrimidine-based inhibitors of dipeptidyl peptidase IV and methods
|
US7314882B2
(en)
*
|
2005-01-12 |
2008-01-01 |
Bristol-Myers Squibb Company |
Bicyclic heterocycles as cannabinoid receptor modulators
|
US7220859B2
(en)
|
2005-01-12 |
2007-05-22 |
Bristol-Myers Squibb Company |
Bicyclic heterocycles as cannabinoid receptor modulators
|
WO2006076597A1
(en)
*
|
2005-01-12 |
2006-07-20 |
Bristol-Myers Squibb Company |
Bicyclic heterocycles as cannabinoid receptor modulators
|
US20060160850A1
(en)
*
|
2005-01-18 |
2006-07-20 |
Chongqing Sun |
Bicyclic heterocycles as cannabinoid receptor modulators
|
US7238702B2
(en)
*
|
2005-02-10 |
2007-07-03 |
Bristol-Myers Squibb Company |
Dihydroquinazolinones as 5HT modulators
|
US20070037979A1
(en)
*
|
2005-02-22 |
2007-02-15 |
Valerie Niddam-Hildesheim |
Preparation of rosuvastatin
|
US20070167625A1
(en)
*
|
2005-02-22 |
2007-07-19 |
Anna Balanov |
Preparation of rosuvastatin
|
ES2389565T3
(es)
|
2005-02-22 |
2012-10-29 |
Teva Pharmaceutical Industries Ltd. |
Rosuvastatina y sales de la misma carentes de alquiléter de rosuvatatina y un procedimiento para la preparación de las mismas
|
US20070293535A1
(en)
*
|
2005-02-24 |
2007-12-20 |
Kowa Company, Ltd. |
Nuclear Transfer Promoter for Ddc42 Protein and Method of Screening the Dame
|
PT1855674E
(pt)
|
2005-03-02 |
2014-10-08 |
Merck Canada Inc |
Composição para a inibição de catepsina k
|
US20080260818A1
(en)
*
|
2005-03-28 |
2008-10-23 |
Dexcel Pharma Technologies Ltd. |
Controlled Absorption of Statins in the Intestine
|
US20060235028A1
(en)
|
2005-04-14 |
2006-10-19 |
Li James J |
Inhibitors of 11-beta hydroxysteroid dehydrogenase type I
|
ATE550019T1
(de)
|
2005-05-17 |
2012-04-15 |
Merck Sharp & Dohme |
Cis-4-ä(4-chlorophenyl)sulfonylü-4-(2,5- difluorophenyl)cyclohexanepropansäure zur behandlug von krebs
|
US7521557B2
(en)
|
2005-05-20 |
2009-04-21 |
Bristol-Myers Squibb Company |
Pyrrolopyridine-based inhibitors of dipeptidyl peptidase IV and methods
|
US7825139B2
(en)
*
|
2005-05-25 |
2010-11-02 |
Forest Laboratories Holdings Limited (BM) |
Compounds and methods for selective inhibition of dipeptidyl peptidase-IV
|
US20060275356A1
(en)
*
|
2005-05-25 |
2006-12-07 |
Burgess James W |
Pharmaceutical compositions for treating or preventing coronary artery disease
|
CN101282991A
(zh)
*
|
2005-05-26 |
2008-10-08 |
布里斯托尔-迈尔斯斯奎布公司 |
N-端修饰的胰高血糖素样肽-1受体调节剂
|
EP1982711A1
(en)
|
2005-05-31 |
2008-10-22 |
Mylan Laboratories, Inc |
Compositions comprsing nebivolol
|
US7632837B2
(en)
*
|
2005-06-17 |
2009-12-15 |
Bristol-Myers Squibb Company |
Bicyclic heterocycles as cannabinoid-1 receptor modulators
|
US7452892B2
(en)
*
|
2005-06-17 |
2008-11-18 |
Bristol-Myers Squibb Company |
Triazolopyrimidine cannabinoid receptor 1 antagonists
|
US7572808B2
(en)
*
|
2005-06-17 |
2009-08-11 |
Bristol-Myers Squibb Company |
Triazolopyridine cannabinoid receptor 1 antagonists
|
US7629342B2
(en)
*
|
2005-06-17 |
2009-12-08 |
Bristol-Myers Squibb Company |
Azabicyclic heterocycles as cannabinoid receptor modulators
|
US20060287342A1
(en)
*
|
2005-06-17 |
2006-12-21 |
Mikkilineni Amarendra B |
Triazolopyrimidine heterocycles as cannabinoid receptor modulators
|
US7317012B2
(en)
*
|
2005-06-17 |
2008-01-08 |
Bristol-Myers Squibb Company |
Bicyclic heterocycles as cannabinoind-1 receptor modulators
|
CA2613522A1
(en)
|
2005-06-27 |
2007-01-04 |
Exelixis, Inc. |
Imidazole based lxr modulators
|
US20070015832A1
(en)
*
|
2005-07-14 |
2007-01-18 |
Myriad Genetics, Incorporated |
Methods of treating overactive bladder and urinary incontinence
|
EP1910361A2
(en)
*
|
2005-07-28 |
2008-04-16 |
Brystol-Myers Squibb Company |
Substituted tetrahydro-1h-pyrido[4,3,b]indoles as serotonin receptor agonists and antagonists
|
US7772277B2
(en)
*
|
2005-08-04 |
2010-08-10 |
Transform Pharmaceuticals, Inc. |
Formulations comprising fenofibrate and a statin, and related methods of treatment
|
WO2007022488A2
(en)
*
|
2005-08-16 |
2007-02-22 |
Teva Pharmaceutical Industries Ltd. |
Crystalline rosuvastatin intermediate
|
US7795436B2
(en)
*
|
2005-08-24 |
2010-09-14 |
Bristol-Myers Squibb Company |
Substituted tricyclic heterocycles as serotonin receptor agonists and antagonists
|
PE20070335A1
(es)
|
2005-08-30 |
2007-04-21 |
Novartis Ag |
Benzimidazoles sustituidos y metodos para su preparacion
|
EP1919393A2
(en)
*
|
2005-09-01 |
2008-05-14 |
Prescient Medical, Inc. |
Drugs coated on a device to treat vulnerable plaque
|
WO2007035395A2
(en)
*
|
2005-09-16 |
2007-03-29 |
Virginia Commonwealth University Intellectual Property Foundation |
Therapeutic compositions comprising chorionic gonadotropins and hmg coa reductase inhibitors
|
US8119358B2
(en)
|
2005-10-11 |
2012-02-21 |
Tethys Bioscience, Inc. |
Diabetes-related biomarkers and methods of use thereof
|
DE102005049293A1
(de)
*
|
2005-10-15 |
2007-04-26 |
Bayer Healthcare Ag |
Kombinationspräparate von Salzen oder o-Acetylsalicylsäure
|
WO2007047880A2
(en)
*
|
2005-10-18 |
2007-04-26 |
Aegerion Pharmaceuticals |
Compositions for lowering serum cholesterol and/or triglycerides
|
US7741317B2
(en)
|
2005-10-21 |
2010-06-22 |
Bristol-Myers Squibb Company |
LXR modulators
|
AR056155A1
(es)
*
|
2005-10-26 |
2007-09-19 |
Bristol Myers Squibb Co |
Antagonistas del receptor 1 de la hormona de concentracion de melanina no basica
|
EP1943215A2
(en)
|
2005-10-31 |
2008-07-16 |
Brystol-Myers Squibb Company |
Pyrrolidinyl beta-amino amide-based inhibitors of dipeptidyl peptidase iv and methods
|
US7888376B2
(en)
|
2005-11-23 |
2011-02-15 |
Bristol-Myers Squibb Company |
Heterocyclic CETP inhibitors
|
US7592461B2
(en)
|
2005-12-21 |
2009-09-22 |
Bristol-Myers Squibb Company |
Indane modulators of glucocorticoid receptor, AP-1, and/or NF-κB activity and use thereof
|
WO2007073935A1
(en)
*
|
2005-12-29 |
2007-07-05 |
Lek Pharmaceuticals D.D. |
Heterocyclic compounds
|
EP1976873A2
(en)
*
|
2006-01-11 |
2008-10-08 |
Brystol-Myers Squibb Company |
Human glucagon-like-peptide-1 modulators and their use in the treatment of diabetes and related conditions
|
US7553836B2
(en)
*
|
2006-02-06 |
2009-06-30 |
Bristol-Myers Squibb Company |
Melanin concentrating hormone receptor-1 antagonists
|
GB0603041D0
(en)
|
2006-02-15 |
2006-03-29 |
Angeletti P Ist Richerche Bio |
Therapeutic compounds
|
US20090069275A1
(en)
*
|
2006-02-17 |
2009-03-12 |
Rocca Jose G |
Low flush niacin formulation
|
CA2569776A1
(en)
*
|
2006-02-17 |
2007-08-17 |
Kos Life Sciences, Inc. |
Low flush niacin formulation
|
US20070238770A1
(en)
*
|
2006-04-05 |
2007-10-11 |
Bristol-Myers Squibb Company |
Process for preparing novel crystalline forms of peliglitazar, novel stable forms produced therein and formulations
|
ES2654847T3
(es)
|
2006-04-19 |
2018-02-15 |
Novartis Ag |
Compuestos de benzoxazol y benzotiazol sustituidos en 6-O y métodos para inhibir la señalización CSF-1R
|
US20070269503A1
(en)
*
|
2006-05-16 |
2007-11-22 |
James Walter Burgess |
Combinations of HMG CoA reductase inhibitors and negatively charged phospholipids and uses thereof
|
WO2007139589A1
(en)
|
2006-05-26 |
2007-12-06 |
Bristol-Myers Squibb Company |
Sustained release glp-1 receptor modulators
|
EP2924440A3
(en)
|
2006-06-07 |
2016-03-09 |
Health Diagnostic Laboratory, Inc. |
Markers associated with arteriovascular events and methods of use thereof
|
US7919598B2
(en)
|
2006-06-28 |
2011-04-05 |
Bristol-Myers Squibb Company |
Crystal structures of SGLT2 inhibitors and processes for preparing same
|
EP2033646A4
(en)
|
2006-06-29 |
2009-11-18 |
Kowa Co |
PROPHYLACTIC AND / OR THERAPEUTIC AGENT FOR THE TREATMENT OF RHEUMATOID ARTHRITIS
|
US20080044326A1
(en)
*
|
2006-07-04 |
2008-02-21 |
Esencia Co., Ltd. |
Sterilizer for baby products
|
US7795291B2
(en)
|
2006-07-07 |
2010-09-14 |
Bristol-Myers Squibb Company |
Substituted acid derivatives useful as anti-atherosclerotic, anti-dyslipidemic, anti-diabetic and anti-obesity agents and method
|
US7727978B2
(en)
|
2006-08-24 |
2010-06-01 |
Bristol-Myers Squibb Company |
Cyclic 11-beta hydroxysteroid dehydrogenase type I inhibitors
|
EP2057987B1
(en)
|
2006-08-30 |
2015-03-04 |
Kyushu University, National University Corporation |
Pharmaceutical composition containing statin-encapsulated nanoparticle
|
EP2698157B1
(en)
|
2006-09-22 |
2015-05-20 |
Merck Sharp & Dohme Corp. |
Method of treatment using fatty acid synthesis inhibitors
|
US20080118572A1
(en)
*
|
2006-10-10 |
2008-05-22 |
Harold Richard Hellstrom |
Methods and compositions for reducing the risk of adverse cardiovascular events associated with the administration of artificial blood
|
EP2079448A2
(en)
*
|
2006-10-10 |
2009-07-22 |
Dexcel Pharma Technologies Ltd. |
Improved release of statins in the intestine
|
WO2008057862A2
(en)
|
2006-11-01 |
2008-05-15 |
Bristol-Myers Squibb Company |
MODULATORS OF GLUCOCORTICOID RECEPTOR, AP-1, AND/OR NF-ϰB ACTIVITY AND USE THEREOF
|
US20110218176A1
(en)
|
2006-11-01 |
2011-09-08 |
Barbara Brooke Jennings-Spring |
Compounds, methods, and treatments for abnormal signaling pathways for prenatal and postnatal development
|
EP2120927A1
(en)
*
|
2006-12-21 |
2009-11-25 |
Aegerion Pharmaceuticals, Inc. |
Methods for treating obesity with a combination comprising a mtp inhibitor and a cholesterol absorption inhibitor
|
EP2109608B1
(en)
|
2007-01-10 |
2011-03-23 |
Istituto di Richerche di Biologia Molecolare P. Angeletti S.p.A. |
Amide substituted indazoles as poly(adp-ribose)polymerase (parp) inhibitors
|
ES2319029B1
(es)
*
|
2007-02-09 |
2010-02-10 |
Universidad De Almeria |
Proceso para la produccion en continuo de lovastatina.
|
EP2114151A4
(en)
*
|
2007-03-01 |
2010-03-17 |
Concourse Health Sciences Llc |
INOSITOL NIACINATE ISOMERS AND USES THEREOF
|
MX2009009304A
(es)
|
2007-03-01 |
2009-11-18 |
Novartis Ag |
Inhibidores de cinasa pim y metodos para su uso.
|
US20080227846A1
(en)
*
|
2007-03-13 |
2008-09-18 |
Musc Foundation For Research Development |
Methods of treating juvenile type 1 diabetes mellitus
|
PE20090185A1
(es)
|
2007-03-22 |
2009-02-28 |
Bristol Myers Squibb Co |
Formulaciones farmaceuticas que contienen un inhibidor sglt2
|
WO2008124121A1
(en)
*
|
2007-04-06 |
2008-10-16 |
Scidose, Llc |
Co-therapy with and combinations of statins and 1,4-dihydropyridine-3,5-dicarboxydiesters
|
CN101795684A
(zh)
*
|
2007-04-09 |
2010-08-04 |
赛多斯有限责任公司 |
他汀类化合物与抗肥胖药的组合
|
US20080249156A1
(en)
*
|
2007-04-09 |
2008-10-09 |
Palepu Nageswara R |
Combinations of statins and anti-obesity agent and glitazones
|
CN101687873A
(zh)
|
2007-04-17 |
2010-03-31 |
百时美施贵宝公司 |
具有稠合杂环的11β-羟基类固醇Ⅰ型脱氢酶抑制剂
|
EP2891885A3
(en)
|
2007-04-18 |
2015-10-14 |
Health Diagnostic Laboratory, Inc. |
Diabetes-related biomarkers and methods of use thereof
|
PE20090696A1
(es)
|
2007-04-20 |
2009-06-20 |
Bristol Myers Squibb Co |
Formas cristalinas de saxagliptina y procesos para preparar las mismas
|
JP4896220B2
(ja)
|
2007-04-27 |
2012-03-14 |
国立大学法人九州大学 |
肺疾患治療薬
|
EP2147008A2
(en)
*
|
2007-05-18 |
2010-01-27 |
Bristol-Myers Squibb Company |
Crystal structures of sglt2 inhibitors and processes for preparing same
|
CN101754965B
(zh)
|
2007-05-21 |
2014-03-19 |
诺华股份有限公司 |
Csf-1r抑制剂、组合物及使用方法
|
EP2581081A3
(en)
|
2007-06-01 |
2013-07-31 |
The Trustees Of Princeton University |
Treatment of viral infections by modulation of host cell metabolic pathways
|
DE102007028320A1
(de)
|
2007-06-20 |
2008-12-24 |
Bayer Healthcare Ag |
Substituierte Oxazolidinone und ihre Verwendung
|
DE102007028319A1
(de)
|
2007-06-20 |
2008-12-24 |
Bayer Healthcare Ag |
Substituierte Oxazolidinone und ihre Verwendung
|
DE102007028407A1
(de)
|
2007-06-20 |
2008-12-24 |
Bayer Healthcare Ag |
Substituierte Oxazolidinone und ihre Verwendung
|
DE102007028406A1
(de)
|
2007-06-20 |
2008-12-24 |
Bayer Healthcare Ag |
Substituierte Oxazolidinone und ihre Verwendung
|
US8389553B2
(en)
|
2007-06-27 |
2013-03-05 |
Merck Sharp & Dohme Corp. |
4-carboxybenzylamino derivatives as histone deacetylase inhibitors
|
US20090011994A1
(en)
*
|
2007-07-06 |
2009-01-08 |
Bristol-Myers Squibb Company |
Non-basic melanin concentrating hormone receptor-1 antagonists and methods
|
JP2010534722A
(ja)
*
|
2007-07-27 |
2010-11-11 |
ブリストル−マイヤーズ スクイブ カンパニー |
新規グルコキナーゼ活性化薬およびその使用方法
|
JOP20080381B1
(ar)
|
2007-08-23 |
2023-03-28 |
Amgen Inc |
بروتينات مرتبطة بمولدات مضادات تتفاعل مع بروبروتين كونفيرتاز سيتيليزين ككسين من النوع 9 (pcsk9)
|
BRPI0817211A2
(pt)
*
|
2007-09-20 |
2017-05-16 |
Irm Llc |
composto composições como moduladores da atividade de gpr119
|
EP2209780B1
(en)
|
2007-11-01 |
2014-01-01 |
Bristol-Myers Squibb Company |
Nonsteroidal compounds useful as modulators of glucocorticoid receptor ap-1 and/or nf- kappa b activity and use thereof
|
WO2009078033A2
(en)
*
|
2007-12-18 |
2009-06-25 |
Themis Medicare Limited |
Isolation and recovery of simvastatin in lactone form or in the form of an acid salt from the harvested fermentation broth
|
CA2709677C
(en)
|
2007-12-21 |
2017-03-14 |
Lin Zhi |
Selective androgen receptor modulators (sarms) and uses thereof
|
MX356760B
(es)
|
2008-01-11 |
2018-06-12 |
Dartmouth College |
Triterpenoides sinteticos y metodos de uso en el tratamiento de enfermedad.
|
WO2009148709A1
(en)
*
|
2008-04-16 |
2009-12-10 |
University Of Utah Research Foundation |
Pharmacological targeting of vascular malformations
|
US9072727B2
(en)
|
2008-04-18 |
2015-07-07 |
Warsaw Orthopedic, Inc. |
Alpha adrenergic receptor agonists for treatment of degenerative disc disease
|
US8420114B2
(en)
|
2008-04-18 |
2013-04-16 |
Warsaw Orthopedic, Inc. |
Alpha and beta adrenergic receptor agonists for treatment of pain and / or inflammation
|
US8557273B2
(en)
|
2008-04-18 |
2013-10-15 |
Medtronic, Inc. |
Medical devices and methods including polymers having biologically active agents therein
|
PE20091928A1
(es)
*
|
2008-05-29 |
2009-12-31 |
Bristol Myers Squibb Co |
Tienopirimidinas hidroxisustituidas como antagonistas de receptor-1 de hormona concentradora de melanina no basicos
|
ES2330184B1
(es)
|
2008-06-03 |
2010-07-05 |
Neuron Biopharma, S.A. |
Uso de estatinas como anticonvulsivantes, antiepilepticos y neuroprotectores.
|
EP2138178A1
(en)
|
2008-06-28 |
2009-12-30 |
Bayer Schering Pharma Aktiengesellschaft |
Oxazolidninones for the treatment fo chronic obstructive pulmonary disease (COPD) and/or asthma
|
EP2161024A1
(de)
|
2008-09-05 |
2010-03-10 |
Universitätsklinikum Hamburg-Eppendorf |
Kombinationspräparat zur Behandlung von Krebs
|
US20120046364A1
(en)
|
2009-02-10 |
2012-02-23 |
Metabasis Therapeutics, Inc. |
Novel Sulfonic Acid-Containing Thyromimetics, and Methods for Their Use
|
WO2010111665A1
(en)
|
2009-03-27 |
2010-09-30 |
Bristol-Myers Squibb Company |
Methods for preventing major adverse cardiovascular events with dpp-iv inhibitors
|
EP2413932A4
(en)
|
2009-04-01 |
2012-09-19 |
Merck Sharp & Dohme |
INHIBITORS OF AKT ACTIVITY
|
US8470805B2
(en)
*
|
2009-04-30 |
2013-06-25 |
Kaohsiung Medical University |
Processes for preparing piperazinium salts of KMUP and use thereof
|
ES2620451T3
(es)
|
2009-05-28 |
2017-06-28 |
Exelixis Patent Company Llc |
Moduladores de los LXR
|
US8765747B2
(en)
|
2009-06-12 |
2014-07-01 |
Dana-Farber Cancer Institute, Inc. |
Fused 2-aminothiazole compounds
|
WO2011014520A2
(en)
|
2009-07-29 |
2011-02-03 |
Irm Llc |
Compounds and compositions as modulators of gpr119 activity
|
KR20120092629A
(ko)
|
2009-10-09 |
2012-08-21 |
아이알엠 엘엘씨 |
Gpr119 활성의 조절제로서의 화합물 및 조성물
|
EP2488028B1
(en)
|
2009-10-14 |
2020-08-19 |
Merck Sharp & Dohme Corp. |
Substituted piperidines that increase p53 activity and the uses thereof
|
CA2780941C
(en)
|
2009-11-13 |
2018-06-12 |
Bristol-Myers Squibb Company |
Immediate release tablet formulations
|
HUE040486T2
(hu)
|
2009-11-13 |
2019-03-28 |
Astrazeneca Ab |
Kétrétegû tabletta készítmények
|
EP2498757A1
(en)
|
2009-11-13 |
2012-09-19 |
Bristol-Myers Squibb Company |
Reduced mass metformin formulations
|
US8394858B2
(en)
|
2009-12-03 |
2013-03-12 |
Novartis Ag |
Cyclohexane derivatives and uses thereof
|
EP2512514B1
(en)
|
2009-12-14 |
2014-11-05 |
Kyoto University |
Screening method for identifying compounds for treating amyotrophic lateral sclerosis
|
EP2519517B1
(en)
|
2009-12-29 |
2015-03-25 |
Dana-Farber Cancer Institute, Inc. |
Type ii raf kinase inhibitors
|
EP2531163A1
(en)
|
2010-02-01 |
2012-12-12 |
The Hospital For Sick Children |
Remote ischemic conditioning for treatment and preventon of restenosis
|
TWI562775B
(en)
|
2010-03-02 |
2016-12-21 |
Lexicon Pharmaceuticals Inc |
Methods of using inhibitors of sodium-glucose cotransporters 1 and 2
|
BR112012023021A2
(pt)
|
2010-03-16 |
2016-05-31 |
Dana Farber Cancer Inst Inc |
compostos de indazol e seus usos
|
KR20130040851A
(ko)
|
2010-03-31 |
2013-04-24 |
더 호스피탈 포 식 칠드런 |
심근 경색 후 결과를 개선시키기 위한 원격 허혈 처치의 사용
|
SG10201908576VA
(en)
|
2010-04-08 |
2019-10-30 |
Hospital For Sick Children |
Use of remote ischemic conditioning for traumatic injury
|
US8592396B2
(en)
|
2010-04-14 |
2013-11-26 |
Bristol-Myers Squibb Company |
Glucokinase activators and methods of using same
|
US8372877B2
(en)
|
2010-04-16 |
2013-02-12 |
Cumberland Pharmaceuticals |
Stabilized statin formulations
|
EP2571860A1
(en)
|
2010-05-21 |
2013-03-27 |
Pfizer Inc |
2-phenyl benzoylamides
|
WO2011163330A1
(en)
|
2010-06-24 |
2011-12-29 |
Merck Sharp & Dohme Corp. |
Novel heterocyclic compounds as erk inhibitors
|
AU2011276254B2
(en)
|
2010-07-09 |
2016-11-03 |
James Trinca Green |
Combination immediate/delayed release delivery system for short half-life pharmaceuticals including remogliflozin
|
US8697739B2
(en)
|
2010-07-29 |
2014-04-15 |
Novartis Ag |
Bicyclic acetyl-CoA carboxylase inhibitors and uses thereof
|
CN103068980B
(zh)
|
2010-08-02 |
2017-04-05 |
瑟纳治疗公司 |
使用短干扰核酸(siNA)的RNA干扰介导的联蛋白(钙粘蛋白关联蛋白质),β1(CTNNB1)基因表达的抑制
|
KR102072631B1
(ko)
|
2010-08-17 |
2020-02-03 |
시르나 쎄러퓨틱스 인코퍼레이티드 |
짧은 간섭 핵산 (siNA)을 사용한 B형 간염 바이러스 (HBV) 유전자 발현의 RNA 간섭 매개 억제
|
US8883801B2
(en)
|
2010-08-23 |
2014-11-11 |
Merck Sharp & Dohme Corp. |
Substituted pyrazolo[1,5-a]pyrimidines as mTOR inhibitors
|
US20130156720A1
(en)
|
2010-08-27 |
2013-06-20 |
Ironwood Pharmaceuticals, Inc. |
Compositions and methods for treating or preventing metabolic syndrome and related diseases and disorders
|
WO2012030685A2
(en)
|
2010-09-01 |
2012-03-08 |
Schering Corporation |
Indazole derivatives useful as erk inhibitors
|
US9242981B2
(en)
|
2010-09-16 |
2016-01-26 |
Merck Sharp & Dohme Corp. |
Fused pyrazole derivatives as novel ERK inhibitors
|
JPWO2012046772A1
(ja)
|
2010-10-06 |
2014-02-24 |
国立大学法人 東京大学 |
リンパ浮腫予防治療剤
|
EP3766975A1
(en)
|
2010-10-29 |
2021-01-20 |
Sirna Therapeutics, Inc. |
Rna interference mediated inhibition of gene expression using short interfering nucleic acid (sina)
|
TWI462739B
(zh)
|
2010-11-02 |
2014-12-01 |
Univ Kaohsiung Medical |
Sildenafil-同族物四級銨哌嗪鹽類之製備及醫療用途
|
WO2012087772A1
(en)
|
2010-12-21 |
2012-06-28 |
Schering Corporation |
Indazole derivatives useful as erk inhibitors
|
TWI631963B
(zh)
|
2011-01-05 |
2018-08-11 |
雷西肯製藥股份有限公司 |
包含鈉-葡萄糖共同輸送體1與2之抑制劑的組合物與應用方法
|
UA110813C2
(uk)
|
2011-01-31 |
2016-02-25 |
Каділа Хелткере Лімітед |
Лікування ліподистрофії
|
EP2675440B1
(en)
|
2011-02-14 |
2020-03-25 |
Merck Sharp & Dohme Corp. |
Cathepsin cysteine protease inhibitors
|
EP2680874A2
(en)
|
2011-03-04 |
2014-01-08 |
Pfizer Inc |
Edn3-like peptides and uses thereof
|
AR088728A1
(es)
|
2011-03-25 |
2014-07-02 |
Bristol Myers Squibb Co |
Moduladores de lxr como prodroga de imidazol
|
US20140046059A1
(en)
|
2011-04-21 |
2014-02-13 |
Piramal Enterprises Limited |
Process for the preparation of morpholino sulfonyl indole derivatives
|
US9023865B2
(en)
|
2011-10-27 |
2015-05-05 |
Merck Sharp & Dohme Corp. |
Compounds that are ERK inhibitors
|
EP2822935B1
(en)
|
2011-11-17 |
2019-05-15 |
Dana-Farber Cancer Institute, Inc. |
Inhibitors of c-jun-n-terminal kinase (jnk)
|
EP2597092A1
(en)
|
2011-11-24 |
2013-05-29 |
Sterling Biotech Limited |
A process for purification of lovastatin
|
EP2797641B1
(en)
|
2011-12-29 |
2019-07-10 |
Trustees Of Tufts College |
Functionalization of biomaterials to control regeneration and inflammation responses
|
EP2809319B1
(en)
|
2012-02-02 |
2018-04-18 |
The University of Sydney |
Improvements in tear film stability
|
US20150299696A1
(en)
|
2012-05-02 |
2015-10-22 |
Sirna Therapeutics, Inc. |
SHORT INTERFERING NUCLEIC ACID (siNA) COMPOSITIONS
|
PL2847228T3
(pl)
|
2012-05-10 |
2019-03-29 |
Bayer Pharma Aktiengesellschaft |
Przeciwciała zdolne do wiązania się z czynnikiem krzepnięcia XI i/lub jego aktywowaną postacią, czynnikiem Xla oraz ich zastosowanie
|
CN107674071B
(zh)
|
2012-05-11 |
2021-12-31 |
同步制药公司 |
作为隐花色素调节剂的含有咔唑的磺酰胺类
|
WO2014022195A1
(en)
|
2012-08-01 |
2014-02-06 |
Tavakoli Zahra |
Free flowing, frozen compositions comprising a therapeutic agent
|
CN102875505B
(zh)
*
|
2012-08-02 |
2015-08-05 |
丽珠集团新北江制药股份有限公司 |
一种美伐他汀的提取精制工艺
|
WO2014052619A1
(en)
|
2012-09-27 |
2014-04-03 |
Irm Llc |
Piperidine derivatives and compositions as modulators of gpr119 activity
|
WO2014052563A2
(en)
|
2012-09-28 |
2014-04-03 |
Merck Sharp & Dohme Corp. |
Novel compounds that are erk inhibitors
|
EP2905029B1
(en)
|
2012-10-04 |
2018-11-21 |
Shionogi&Co., Ltd. |
Drug for inhibiting malignant tumor metastasis
|
EP2909194A1
(en)
|
2012-10-18 |
2015-08-26 |
Dana-Farber Cancer Institute, Inc. |
Inhibitors of cyclin-dependent kinase 7 (cdk7)
|
WO2014063061A1
(en)
|
2012-10-19 |
2014-04-24 |
Dana-Farber Cancer Institute, Inc. |
Hydrophobically tagged small molecules as inducers of protein degradation
|
US10000483B2
(en)
|
2012-10-19 |
2018-06-19 |
Dana-Farber Cancer Institute, Inc. |
Bone marrow on X chromosome kinase (BMX) inhibitors and uses thereof
|
NZ707859A
(en)
|
2012-11-20 |
2019-03-29 |
Lexicon Pharmaceuticals Inc |
Inhibitors of sodium glucose cotransporter 1
|
ES2651347T3
(es)
|
2012-11-28 |
2018-01-25 |
Merck Sharp & Dohme Corp. |
Composiciones y métodos para el tratamiento del cáncer
|
CA2895504A1
(en)
|
2012-12-20 |
2014-06-26 |
Merck Sharp & Dohme Corp. |
Substituted imidazopyridines as hdm2 inhibitors
|
US9540377B2
(en)
|
2013-01-30 |
2017-01-10 |
Merck Sharp & Dohme Corp. |
2,6,7,8 substituted purines as HDM2 inhibitors
|
US9834542B2
(en)
|
2013-03-15 |
2017-12-05 |
Bristo-Myers Squibb Company |
LXR modulators
|
AU2014235854B2
(en)
|
2013-03-21 |
2019-04-11 |
Eupraxia Pharmaceuticals USA LLC |
Injectable sustained release composition and method of using the same for treating inflammation in joints and pain associated therewith
|
BR112015026513A2
(pt)
|
2013-04-17 |
2017-07-25 |
Pfizer |
derivados de n-piperidin-3-ilbenzamida para tratar as doenças cardiovasculares
|
EP2988736A1
(en)
|
2013-04-22 |
2016-03-02 |
Cadila Healthcare Limited |
A novel composition for nonalcoholic fatty liver disease (nafld)
|
EP3004053B1
(en)
|
2013-05-30 |
2021-03-24 |
Cadila Healthcare Limited |
A process for preparation of pyrroles having hypolipidemic hypocholesteremic activities
|
EP2810644A1
(en)
|
2013-06-06 |
2014-12-10 |
Ferrer Internacional, S.A. |
Oral formulation for the treatment of cardiovascular diseases
|
TW201636015A
(zh)
|
2013-07-05 |
2016-10-16 |
卡地拉保健有限公司 |
協同性組成物
|
IN2013MU02470A
(no)
|
2013-07-25 |
2015-06-26 |
Cadila Healthcare Ltd |
|
US9593113B2
(en)
|
2013-08-22 |
2017-03-14 |
Bristol-Myers Squibb Company |
Imide and acylurea derivatives as modulators of the glucocorticoid receptor
|
WO2015034925A1
(en)
|
2013-09-03 |
2015-03-12 |
Moderna Therapeutics, Inc. |
Circular polynucleotides
|
WO2015033357A2
(en)
|
2013-09-06 |
2015-03-12 |
Cadila Healthcare Limited |
An improved process for the preparation of pyrrole derivatives
|
WO2015051479A1
(en)
|
2013-10-08 |
2015-04-16 |
Merck Sharp & Dohme Corp. |
Cathepsin cysteine protease inhibitors
|
RU2692799C2
(ru)
|
2013-10-08 |
2019-06-27 |
Мерк Шарп И Доум Корп. |
Ингибиторы цистеинпротеаз катепсинов
|
US20160264551A1
(en)
|
2013-10-18 |
2016-09-15 |
Syros Pharmaceuticals, Inc. |
Heteroaromatic compounds useful for the treatment of prolferative diseases
|
EP3057956B1
(en)
|
2013-10-18 |
2021-05-05 |
Dana-Farber Cancer Institute, Inc. |
Polycyclic inhibitors of cyclin-dependent kinase 7 (cdk7)
|
JP6536871B2
(ja)
|
2013-12-02 |
2019-07-03 |
国立大学法人京都大学 |
Fgfr3病の予防および治療剤ならびにそのスクリーニング方法
|
US10441567B2
(en)
|
2014-01-17 |
2019-10-15 |
Ligand Pharmaceuticals Incorporated |
Methods and compositions for modulating hormone levels
|
WO2015120580A1
(en)
|
2014-02-11 |
2015-08-20 |
Merck Sharp & Dohme Corp. |
Cathepsin cysteine protease inhibitors
|
TWI690521B
(zh)
|
2014-04-07 |
2020-04-11 |
美商同步製藥公司 |
作為隱花色素調節劑之含有咔唑之醯胺類、胺基甲酸酯類及脲類
|
WO2015164604A1
(en)
|
2014-04-23 |
2015-10-29 |
Dana-Farber Cancer Institute, Inc. |
Hydrophobically tagged janus kinase inhibitors and uses thereof
|
WO2015164614A1
(en)
|
2014-04-23 |
2015-10-29 |
Dana-Farber Cancer Institute, Inc. |
Janus kinase inhibitors and uses thereof
|
JO3589B1
(ar)
|
2014-08-06 |
2020-07-05 |
Novartis Ag |
مثبطات كيناز البروتين c وطرق استخداماتها
|
ES2822561T3
(es)
|
2014-09-15 |
2021-05-04 |
Univ Leland Stanford Junior |
Direccionamiento a enfermedad por aneurisma modulando las vías de fagocitosis
|
WO2016055901A1
(en)
|
2014-10-08 |
2016-04-14 |
Pfizer Inc. |
Substituted amide compounds
|
WO2016105528A2
(en)
|
2014-12-23 |
2016-06-30 |
Dana-Farber Cancer Institute, Inc. |
Inhibitors of cyclin-dependent kinase 7 (cdk7)
|
ES2941387T3
(es)
|
2015-02-27 |
2023-05-22 |
Univ Leland Stanford Junior |
Terapia de combinación para el tratamiento de la ateroesclerosis
|
US10550121B2
(en)
|
2015-03-27 |
2020-02-04 |
Dana-Farber Cancer Institute, Inc. |
Inhibitors of cyclin-dependent kinases
|
US10736871B2
(en)
|
2015-04-01 |
2020-08-11 |
Cedars-Sinai Medical Center |
Anti-methanogenic lovastatin analogs or derivatives and uses thereof
|
WO2016168492A1
(en)
|
2015-04-14 |
2016-10-20 |
Hur Soojung Claire |
Electrode array for vortex-assisted electroporation
|
JP2018515082A
(ja)
|
2015-04-30 |
2018-06-14 |
プレジデント アンド フェローズ オブ ハーバード カレッジ |
代謝障害を処置するための抗ap2抗体及び抗原結合剤
|
WO2016201370A1
(en)
|
2015-06-12 |
2016-12-15 |
Dana-Farber Cancer Institute, Inc. |
Combination therapy of transcription inhibitors and kinase inhibitors
|
EP4019515A1
(en)
|
2015-09-09 |
2022-06-29 |
Dana-Farber Cancer Institute, Inc. |
Inhibitors of cyclin-dependent kinases
|
US10385017B2
(en)
|
2015-10-14 |
2019-08-20 |
Cadila Healthcare Limited |
Pyrrole compound, compositions and process for preparation thereof
|
PL3206672T3
(pl)
|
2015-10-27 |
2018-09-28 |
Eupraxia Pharmaceuticals Inc. |
Preparaty o przedłużonym uwalnianiu środków znieczulających miejscowo
|
US20180243263A1
(en)
|
2016-12-09 |
2018-08-30 |
Cadila Healthcare Ltd. |
Treatment for primary biliary cholangitis
|
US20200129440A1
(en)
|
2017-01-23 |
2020-04-30 |
Dong Wha Pharm. Co., Ltd. |
Complex formulation comprising hmg-coa reductase inhibitor and clopidogrel
|
ES2921205T3
(es)
|
2017-11-02 |
2022-08-19 |
Consejo Superior Investigacion |
Uso de estatinas para superar la resistencia a los antibióticos betalactámicos en especies bacterianas que sintetizan isoprenoides mediante la ruta de síntesis de mevalonato
|
US10947234B2
(en)
|
2017-11-08 |
2021-03-16 |
Merck Sharp & Dohme Corp. |
PRMT5 inhibitors
|
BR112021000139A2
(pt)
|
2018-07-19 |
2021-04-06 |
Astrazeneca Ab |
Métodos de tratamento da hfpef empregando dapagliflozina e composições compreendendo a mesma
|
US20210299331A1
(en)
|
2018-07-19 |
2021-09-30 |
Kyoto University |
Pluripotent stem cell-derived plate-shaped cartilage and method for producing the same
|
WO2020033282A1
(en)
|
2018-08-07 |
2020-02-13 |
Merck Sharp & Dohme Corp. |
Prmt5 inhibitors
|
WO2020033284A1
(en)
|
2018-08-07 |
2020-02-13 |
Merck Sharp & Dohme Corp. |
Prmt5 inhibitors
|
BR112021004839A2
(pt)
|
2018-09-26 |
2021-06-08 |
Lexicon Pharmaceuticals, Inc. |
formas cristalinas de n-(1-((2-(dimetilamino)etil)amino)-2-metil-1-oxopropan-2-il)-4-(4-(2-metil-5-((2s,3r,4r,5s,6r)-3,4,5-triidróxi-6-(metiltio)tetraidro-2h-piran-2-il)benzil)fenil)butanamida e métodos de sua síntese
|
EP3900787A4
(en)
|
2018-12-21 |
2022-02-23 |
Kyoto University |
CARTILAGE-LIKE TISSUE WITH LOCALIZED LUBRICINE, METHOD FOR THE PRODUCTION THEREOF, AND COMPOSITION COMPRISING IT FOR THE TREATMENT OF ARTICULAR CARTILAGE LESIONS
|
MX2021008533A
(es)
|
2019-01-18 |
2021-08-19 |
Astrazeneca Ab |
Inhibidores de la pcsk9 y metodos de uso de los mismos.
|
PE20220164A1
(es)
|
2019-05-27 |
2022-01-28 |
Immatics Us Inc |
Vectores viricos y uso de los mismos en terapias celulares adoptivas
|
WO2021126731A1
(en)
|
2019-12-17 |
2021-06-24 |
Merck Sharp & Dohme Corp. |
Prmt5 inhibitors
|
US20230172996A1
(en)
|
2020-02-21 |
2023-06-08 |
Yoshikazu NAKAOKA |
Composition for alleviating pulmonary hypertension, method for predicting prognosis of pulmonary hypertension, method for assisting in determining severity of pulmonary hypertension, and method for assisting in diagnosing pulmonary hypertension
|
DE102020111571A1
(de)
|
2020-03-11 |
2021-09-16 |
Immatics US, Inc. |
Wpre-mutantenkonstrukte, zusammensetzungen und zugehörige verfahren
|
US20220023252A1
(en)
|
2020-07-27 |
2022-01-27 |
Astrazeneca Ab |
Methods of treating chronic kidney disease with dapagliflozin
|
WO2022040631A1
(en)
|
2020-08-21 |
2022-02-24 |
Immatics US, Inc. |
Methods for isolating cd8+ selected t cells
|
WO2023144722A1
(en)
|
2022-01-26 |
2023-08-03 |
Astrazeneca Ab |
Dapagliflozin for use in the treatment of prediabetes or reducing the risk of developing type 2 diabetes
|