MX382352B - Compuestos de heteroarilo y usos de los mismos. - Google Patents

Compuestos de heteroarilo y usos de los mismos.

Info

Publication number
MX382352B
MX382352B MX2018014373A MX2018014373A MX382352B MX 382352 B MX382352 B MX 382352B MX 2018014373 A MX2018014373 A MX 2018014373A MX 2018014373 A MX2018014373 A MX 2018014373A MX 382352 B MX382352 B MX 382352B
Authority
MX
Mexico
Prior art keywords
heteroaryl compounds
formula
methods
pharmaceutically acceptable
same
Prior art date
Application number
MX2018014373A
Other languages
English (en)
Inventor
Arthur F Kluge
Deqiang Niu
Hormoz Mazdiyasni
Juswinder Singh
Lixin Qiao
Richland Wayne Tester
Russell C Petter
William Frederick Westlin
Original Assignee
Celgene Car Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Celgene Car Llc filed Critical Celgene Car Llc
Publication of MX382352B publication Critical patent/MX382352B/es

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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
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    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
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Abstract

La presente invención proporciona inhibidores de proteína cinasas de las fórmulas I-a e I-b, composiciones farmacéuticamente aceptables de los mismos, y método para usar los mismos.
MX2018014373A 2008-06-27 2009-06-26 Compuestos de heteroarilo y usos de los mismos. MX382352B (es)

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