MX355418B - Anticuerpos que se unen a factor estimulante de colonias 1 (csf1r). - Google Patents
Anticuerpos que se unen a factor estimulante de colonias 1 (csf1r).Info
- Publication number
- MX355418B MX355418B MX2015007635A MX2015007635A MX355418B MX 355418 B MX355418 B MX 355418B MX 2015007635 A MX2015007635 A MX 2015007635A MX 2015007635 A MX2015007635 A MX 2015007635A MX 355418 B MX355418 B MX 355418B
- Authority
- MX
- Mexico
- Prior art keywords
- antibodies
- csf1r
- bind
- methods
- chains
- Prior art date
Links
- 101000916644 Homo sapiens Macrophage colony-stimulating factor 1 receptor Proteins 0.000 abstract 3
- 102100028198 Macrophage colony-stimulating factor 1 receptor Human genes 0.000 abstract 3
- 102000040430 polynucleotide Human genes 0.000 abstract 2
- 108091033319 polynucleotide Proteins 0.000 abstract 2
- 239000002157 polynucleotide Substances 0.000 abstract 2
- 206010065687 Bone loss Diseases 0.000 abstract 1
- 108091011896 CSF1 Proteins 0.000 abstract 1
- 102100028123 Macrophage colony-stimulating factor 1 Human genes 0.000 abstract 1
- 201000006417 multiple sclerosis Diseases 0.000 abstract 1
- 206010039073 rheumatoid arthritis Diseases 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
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- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/51—Complete heavy chain or Fd fragment, i.e. VH + CH1
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/515—Complete light chain, i.e. VL + CL
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
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- C07K2317/55—Fab or Fab'
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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- C07K2317/565—Complementarity determining region [CDR]
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- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
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- C07—ORGANIC CHEMISTRY
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
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- C07—ORGANIC CHEMISTRY
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- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
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Abstract
La presente invención se refiere a anticuerpos que se unen a CSF1 R. También se proporcionan cadenas pesadas y cadenas ligeras de anticuerpo que son capaces de formar anticuerpos que se unen a CSF1R. Se proporcionan polinucleátidos que codifican anticuerpos para CSF1R. También se proporcionan polinucleótidos que codifican cadenas pesadas y cadenas ligeras de anticuerpo. Se proporcionan métodos de tratamiento que usan anticuerpos para CSF1R. Los métodos incluyen, de modo no taxativo, métodos para tratar artritis reumatoide, pérdida de masa ósea y esclerosis múltiple.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US33117710P | 2010-05-04 | 2010-05-04 | |
| PCT/US2011/035231 WO2011140249A2 (en) | 2010-05-04 | 2011-05-04 | Antibodies that bind csf1r |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX355418B true MX355418B (es) | 2018-04-18 |
Family
ID=44902080
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2017015045A MX378336B (es) | 2010-05-04 | 2011-05-04 | Anticuerpos que se unen a factor estimulante de colonias 1 (csf1r). |
| MX2012012790A MX2012012790A (es) | 2010-05-04 | 2011-05-04 | Anticuerpos que se unen a factor estimulante de colonias 1 (csf1r). |
| MX2015007635A MX355418B (es) | 2010-05-04 | 2011-05-04 | Anticuerpos que se unen a factor estimulante de colonias 1 (csf1r). |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2017015045A MX378336B (es) | 2010-05-04 | 2011-05-04 | Anticuerpos que se unen a factor estimulante de colonias 1 (csf1r). |
| MX2012012790A MX2012012790A (es) | 2010-05-04 | 2011-05-04 | Anticuerpos que se unen a factor estimulante de colonias 1 (csf1r). |
Country Status (27)
| Country | Link |
|---|---|
| US (8) | US8206715B2 (es) |
| EP (3) | EP3357510B1 (es) |
| JP (6) | JP6008842B2 (es) |
| KR (3) | KR20200044999A (es) |
| CN (4) | CN107011438B (es) |
| AU (4) | AU2011248083B2 (es) |
| BR (1) | BR112012027994B1 (es) |
| CA (1) | CA2797399C (es) |
| CY (1) | CY1121102T1 (es) |
| DK (1) | DK2566517T3 (es) |
| EA (1) | EA036336B1 (es) |
| ES (2) | ES2706412T3 (es) |
| HR (1) | HRP20190047T1 (es) |
| HU (1) | HUE042898T2 (es) |
| IL (3) | IL222629B (es) |
| LT (1) | LT2566517T (es) |
| MX (3) | MX378336B (es) |
| NZ (3) | NZ712765A (es) |
| PL (1) | PL2566517T3 (es) |
| PT (1) | PT2566517T (es) |
| RS (1) | RS58211B1 (es) |
| SG (3) | SG185035A1 (es) |
| SI (1) | SI2566517T1 (es) |
| SM (1) | SMT201900074T1 (es) |
| TR (1) | TR201900368T4 (es) |
| TW (5) | TW202112827A (es) |
| WO (1) | WO2011140249A2 (es) |
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