KR20200036808A - 진행성 핵상 마비 치료를 위한 PPARγ 작용제 - Google Patents

진행성 핵상 마비 치료를 위한 PPARγ 작용제 Download PDF

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KR20200036808A
KR20200036808A KR1020197032448A KR20197032448A KR20200036808A KR 20200036808 A KR20200036808 A KR 20200036808A KR 1020197032448 A KR1020197032448 A KR 1020197032448A KR 20197032448 A KR20197032448 A KR 20197032448A KR 20200036808 A KR20200036808 A KR 20200036808A
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light chain
reduction
chain protein
pharmaceutical composition
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바바라 핀크
데이비드 이. 웨인스테인
사리타 케이. 제인
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코히러스 바이오사이언시스, 인크.
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/0004—Screening or testing of compounds for diagnosis of disorders, assessment of conditions, e.g. renal clearance, gastric emptying, testing for diabetes, allergy, rheuma, pancreas functions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

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  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pathology (AREA)
  • Rheumatology (AREA)
  • Toxicology (AREA)
  • Urology & Nephrology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
KR1020197032448A 2017-04-03 2018-04-03 진행성 핵상 마비 치료를 위한 PPARγ 작용제 Ceased KR20200036808A (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201762480838P 2017-04-03 2017-04-03
US62/480,838 2017-04-03
US201862651653P 2018-04-02 2018-04-02
US62/651,653 2018-04-02
PCT/US2018/025923 WO2018187350A1 (en) 2017-04-03 2018-04-03 PPARγ AGONIST FOR TREATMENT OF PROGRESSIVE SUPRANUCLEAR PALSY

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KR20200036808A true KR20200036808A (ko) 2020-04-07

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KR1020197032448A Ceased KR20200036808A (ko) 2017-04-03 2018-04-03 진행성 핵상 마비 치료를 위한 PPARγ 작용제

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US (1) US11253508B2 (enExample)
EP (1) EP3606527A1 (enExample)
JP (1) JP2020515639A (enExample)
KR (1) KR20200036808A (enExample)
CN (1) CN110996951A (enExample)
AU (1) AU2018249822A1 (enExample)
BR (1) BR112019020485A2 (enExample)
CA (1) CA3058806A1 (enExample)
IL (1) IL269705A (enExample)
MX (1) MX2019011867A (enExample)
SG (1) SG11201909046XA (enExample)
WO (1) WO2018187350A1 (enExample)

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Publication number Priority date Publication date Assignee Title
US20100222489A1 (en) 2009-02-27 2010-09-02 Jiang Dayue D Copolymer composition, membrane article, and methods thereof
HK1249847A1 (zh) 2015-03-09 2018-11-16 Intekrin Therapeutics, Inc. 用於治疗非酒精性脂肪肝疾病和/或脂肪营养不良的方法
KR20200036808A (ko) 2017-04-03 2020-04-07 코히러스 바이오사이언시스, 인크. 진행성 핵상 마비 치료를 위한 PPARγ 작용제
EA201992364A1 (ru) * 2018-04-02 2020-03-23 Кохерус Байосайенсис Инк. АГОНИСТ PPARγ ДЛЯ ЛЕЧЕНИЯ ПРОГРЕССИРУЮЩЕГО НАДЪЯДЕРНОГО ПАРАЛИЧА
US20250020669A1 (en) * 2021-02-10 2025-01-16 Washington University Methods for detecting neurofilament light chain in plasma and cerebrospinal fluid

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