KR101433381B1 - 다발성 골수종의 치료를 위한 cd38에 대한 항체 - Google Patents
다발성 골수종의 치료를 위한 cd38에 대한 항체 Download PDFInfo
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- KR101433381B1 KR101433381B1 KR1020077024204A KR20077024204A KR101433381B1 KR 101433381 B1 KR101433381 B1 KR 101433381B1 KR 1020077024204 A KR1020077024204 A KR 1020077024204A KR 20077024204 A KR20077024204 A KR 20077024204A KR 101433381 B1 KR101433381 B1 KR 101433381B1
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- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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- C—CHEMISTRY; METALLURGY
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- C12Y204/00—Glycosyltransferases (2.4)
- C12Y204/99—Glycosyltransferases (2.4) transferring other glycosyl groups (2.4.99)
- C12Y204/99002—Monosialoganglioside sialyltransferase (2.4.99.2)
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- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
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- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
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- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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- C07K2317/565—Complementarity determining region [CDR]
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- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
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- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
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- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/77—Internalization into the cell
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- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
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- G01N2333/91091—Glycosyltransferases (2.4)
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
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- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biomedical Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Urology & Nephrology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Hematology (AREA)
- Wood Science & Technology (AREA)
- Epidemiology (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- General Engineering & Computer Science (AREA)
- Rheumatology (AREA)
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Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA200500429 | 2005-03-23 | ||
| DKPA200500429 | 2005-03-23 | ||
| US66757905P | 2005-04-01 | 2005-04-01 | |
| USUS60/667,579 | 2005-04-01 | ||
| US69616305P | 2005-07-01 | 2005-07-01 | |
| USUS60/696,163 | 2005-07-01 | ||
| US72856105P | 2005-10-20 | 2005-10-20 | |
| USUS60/728,561 | 2005-10-20 | ||
| PCT/DK2006/000166 WO2006099875A1 (en) | 2005-03-23 | 2006-03-23 | Antibodies against cd38 for treatment of multiple myeloma |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020147004315A Division KR20140033240A (ko) | 2005-03-23 | 2006-03-23 | 다발성 골수종의 치료를 위한 cd38에 대한 항체 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR20070116137A KR20070116137A (ko) | 2007-12-06 |
| KR101433381B1 true KR101433381B1 (ko) | 2014-10-02 |
Family
ID=36617365
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020077024204A Active KR101433381B1 (ko) | 2005-03-23 | 2006-03-23 | 다발성 골수종의 치료를 위한 cd38에 대한 항체 |
Country Status (27)
| Country | Link |
|---|---|
| US (5) | US7829673B2 (OSRAM) |
| EP (6) | EP2567976B1 (OSRAM) |
| JP (12) | JP5225069B2 (OSRAM) |
| KR (1) | KR101433381B1 (OSRAM) |
| CN (4) | CN107033243B (OSRAM) |
| AU (1) | AU2006226733C9 (OSRAM) |
| BR (1) | BRPI0608927B1 (OSRAM) |
| CA (1) | CA2602375C (OSRAM) |
| CY (3) | CY1118369T1 (OSRAM) |
| DK (1) | DK2567976T3 (OSRAM) |
| EA (2) | EA037929B1 (OSRAM) |
| ES (1) | ES2716874T3 (OSRAM) |
| FR (1) | FR18C1003I2 (OSRAM) |
| HR (2) | HRP20161766T1 (OSRAM) |
| IL (8) | IL185751A (OSRAM) |
| LT (1) | LTC2567976I2 (OSRAM) |
| LU (1) | LUC00053I9 (OSRAM) |
| ME (1) | ME03528B (OSRAM) |
| MX (1) | MX2007011064A (OSRAM) |
| NL (1) | NL300915I2 (OSRAM) |
| NZ (2) | NZ561883A (OSRAM) |
| PL (1) | PL2567976T3 (OSRAM) |
| RS (1) | RS59399B1 (OSRAM) |
| SG (1) | SG10201912554TA (OSRAM) |
| SI (1) | SI2567976T1 (OSRAM) |
| WO (1) | WO2006099875A1 (OSRAM) |
| ZA (1) | ZA200709003B (OSRAM) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20170088969A (ko) * | 2014-12-04 | 2017-08-02 | 얀센 바이오테크 인코포레이티드 | 급성 골수성 백혈병을 치료하기 위한 항-cd38 항체 |
Families Citing this family (250)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1642983A (zh) | 2002-01-25 | 2005-07-20 | G2治疗有限公司 | 抗C5aR抗体及其应用 |
| SI2511297T1 (sl) | 2004-02-06 | 2015-07-31 | Morphosys Ag | Proti -CD38 humana protitelesa in njihova uporaba |
| US9200061B2 (en) | 2004-02-06 | 2015-12-01 | Morpho Sys AG | Generation and profiling of fully human HuCAL gold®-derived therapeutic antibodies specific for human CD3i |
| SG10201912554TA (en) | 2005-03-23 | 2020-02-27 | Genmab As | Antibodies against cd38 for treatment of multiple myeloma |
| CN103554260A (zh) | 2005-10-12 | 2014-02-05 | 莫佛塞斯公司 | 特异性针对人CD38的完全人HuCAL GOLD-衍生治疗抗体的生成和鉴定 |
| KR20080090414A (ko) * | 2005-12-06 | 2008-10-08 | 도만티스 리미티드 | 세포 표면 표적에 대한 결합 특이성이 있는 이중 특이성리간드 및 이의 사용방법 |
| CA2656620C (en) | 2006-07-04 | 2018-03-13 | Genmab A/S | Cd20 binding molecules for the treatment of copd |
| US20090029904A1 (en) * | 2006-07-21 | 2009-01-29 | Sean Oldham | Compositions and methods for treatment of insulin-resistance diseases |
| CA2664333A1 (en) * | 2006-09-15 | 2008-03-20 | Memorial Sloan Kettering Cancer Center | Methods of diagnosing, treating, or preventing plasma cell disorders |
| PL2081595T3 (pl) * | 2006-09-26 | 2019-11-29 | Genmab As | Anty-cd38 wraz z kortykosteroidami wraz ze środkiem chemioterapeutycznym niebędącym kortykosteroidem, do leczenia guzów nowotworowych |
| WO2008040348A2 (en) * | 2006-10-03 | 2008-04-10 | Genmab A/S | High througput methods for characterization of antibodies |
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| KR20170088969A (ko) * | 2014-12-04 | 2017-08-02 | 얀센 바이오테크 인코포레이티드 | 급성 골수성 백혈병을 치료하기 위한 항-cd38 항체 |
| KR102597989B1 (ko) * | 2014-12-04 | 2023-11-02 | 얀센 바이오테크 인코포레이티드 | 급성 골수성 백혈병을 치료하기 위한 항-cd38 항체 |
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