JP5021115B2 - 電気化学分析物センサ - Google Patents
電気化学分析物センサ Download PDFInfo
- Publication number
- JP5021115B2 JP5021115B2 JP2000534874A JP2000534874A JP5021115B2 JP 5021115 B2 JP5021115 B2 JP 5021115B2 JP 2000534874 A JP2000534874 A JP 2000534874A JP 2000534874 A JP2000534874 A JP 2000534874A JP 5021115 B2 JP5021115 B2 JP 5021115B2
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- JP
- Japan
- Prior art keywords
- sensor
- analyte
- working electrode
- substrate
- electrode
- Prior art date
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
- A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/01—Measuring temperature of body parts ; Diagnostic temperature sensing, e.g. for malignant or inflamed tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
- A61B5/14542—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring blood gases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
- A61B5/14546—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring analytes not otherwise provided for, e.g. ions, cytochromes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
- A61B5/1468—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means
- A61B5/1473—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means invasive, e.g. introduced into the body by a catheter
- A61B5/14735—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means invasive, e.g. introduced into the body by a catheter comprising an immobilised reagent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
- A61B5/1468—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means
- A61B5/1486—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means using enzyme electrodes, e.g. with immobilised oxidase
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
- A61B5/1468—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means
- A61B5/1486—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means using enzyme electrodes, e.g. with immobilised oxidase
- A61B5/14865—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means using enzyme electrodes, e.g. with immobilised oxidase invasive, e.g. introduced into the body by a catheter or needle or using implanted sensors
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/001—Enzyme electrodes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/001—Enzyme electrodes
- C12Q1/005—Enzyme electrodes involving specific analytes or enzymes
- C12Q1/006—Enzyme electrodes involving specific analytes or enzymes for glucose
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Physics & Mathematics (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pathology (AREA)
- Heart & Thoracic Surgery (AREA)
- Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Public Health (AREA)
- Medical Informatics (AREA)
- Optics & Photonics (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Wood Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Emergency Medicine (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/034,372 | 1998-03-04 | ||
| US09/034,372 US6134461A (en) | 1998-03-04 | 1998-03-04 | Electrochemical analyte |
| PCT/US1999/001392 WO1999045387A2 (en) | 1998-03-04 | 1999-01-21 | Electrochemical analyte sensor |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011173021A Division JP2012011208A (ja) | 1998-03-04 | 2011-08-08 | 電気化学分析物センサ |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2002506209A JP2002506209A (ja) | 2002-02-26 |
| JP2002506209A5 JP2002506209A5 (enExample) | 2006-05-25 |
| JP5021115B2 true JP5021115B2 (ja) | 2012-09-05 |
Family
ID=21876004
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000534874A Expired - Lifetime JP5021115B2 (ja) | 1998-03-04 | 1999-01-21 | 電気化学分析物センサ |
| JP2011173021A Pending JP2012011208A (ja) | 1998-03-04 | 2011-08-08 | 電気化学分析物センサ |
| JP2015128508A Expired - Lifetime JP6395055B2 (ja) | 1998-03-04 | 2015-06-26 | 電気化学分析物センサ |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011173021A Pending JP2012011208A (ja) | 1998-03-04 | 2011-08-08 | 電気化学分析物センサ |
| JP2015128508A Expired - Lifetime JP6395055B2 (ja) | 1998-03-04 | 2015-06-26 | 電気化学分析物センサ |
Country Status (5)
| Country | Link |
|---|---|
| US (8) | US6134461A (enExample) |
| EP (2) | EP1060394B1 (enExample) |
| JP (3) | JP5021115B2 (enExample) |
| AU (1) | AU2465999A (enExample) |
| WO (1) | WO1999045387A2 (enExample) |
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| USD820988S1 (en) | 2017-01-20 | 2018-06-19 | Sano Intelligence, Inc. | Biomonitoring sensor system for monitoring body chemistry |
| USD824034S1 (en) | 2016-12-15 | 2018-07-24 | Sano Intelligence, Inc. | Biomonitoring interface device |
| US10173042B2 (en) | 2013-03-14 | 2019-01-08 | Sano Intelligence, Inc. | Method of manufacturing a sensor for sensing analytes |
| US10595754B2 (en) | 2014-03-13 | 2020-03-24 | Sano Intelligence, Inc. | System for monitoring body chemistry |
| US11272866B2 (en) | 2014-03-13 | 2022-03-15 | One Drop Biosensor Technologies, Llc | Wearable microneedle patch |
| US11272885B2 (en) | 2013-03-14 | 2022-03-15 | One Drop Biosensor Technologies, Llc | Wearable multi-analyte microsensor |
| USD988882S1 (en) | 2021-04-21 | 2023-06-13 | Informed Data Systems Inc. | Sensor assembly |
| USD1076079S1 (en) | 2021-04-21 | 2025-05-20 | One Health Biosensing Inc. | Applicator assembly |
| USD1086030S1 (en) | 2021-04-21 | 2025-07-29 | One Health Biosensing Inc. | Charging station |
Families Citing this family (993)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2050057A1 (en) | 1991-03-04 | 1992-09-05 | Adam Heller | Interferant eliminating biosensors |
| US5593852A (en) * | 1993-12-02 | 1997-01-14 | Heller; Adam | Subcutaneous glucose electrode |
| AU6157898A (en) | 1997-02-06 | 1998-08-26 | E. Heller & Company | Small volume (in vitro) analyte sensor |
| US6001067A (en) | 1997-03-04 | 1999-12-14 | Shults; Mark C. | Device and method for determining analyte levels |
| US7192450B2 (en) | 2003-05-21 | 2007-03-20 | Dexcom, Inc. | Porous membranes for use with implantable devices |
| US8527026B2 (en) | 1997-03-04 | 2013-09-03 | Dexcom, Inc. | Device and method for determining analyte levels |
| US9155496B2 (en) | 1997-03-04 | 2015-10-13 | Dexcom, Inc. | Low oxygen in vivo analyte sensor |
| US20050033132A1 (en) | 1997-03-04 | 2005-02-10 | Shults Mark C. | Analyte measuring device |
| US7899511B2 (en) | 2004-07-13 | 2011-03-01 | Dexcom, Inc. | Low oxygen in vivo analyte sensor |
| US6862465B2 (en) | 1997-03-04 | 2005-03-01 | Dexcom, Inc. | Device and method for determining analyte levels |
| US7657297B2 (en) | 2004-05-03 | 2010-02-02 | Dexcom, Inc. | Implantable analyte sensor |
| US6060327A (en) | 1997-05-14 | 2000-05-09 | Keensense, Inc. | Molecular wire injection sensors |
| US7220550B2 (en) * | 1997-05-14 | 2007-05-22 | Keensense, Inc. | Molecular wire injection sensors |
| US6699667B2 (en) | 1997-05-14 | 2004-03-02 | Keensense, Inc. | Molecular wire injection sensors |
| US6036924A (en) | 1997-12-04 | 2000-03-14 | Hewlett-Packard Company | Cassette of lancet cartridges for sampling blood |
| US7407811B2 (en) | 1997-12-22 | 2008-08-05 | Roche Diagnostics Operations, Inc. | System and method for analyte measurement using AC excitation |
| US7390667B2 (en) | 1997-12-22 | 2008-06-24 | Roche Diagnostics Operations, Inc. | System and method for analyte measurement using AC phase angle measurements |
| US7494816B2 (en) | 1997-12-22 | 2009-02-24 | Roche Diagnostic Operations, Inc. | System and method for determining a temperature during analyte measurement |
| US8071384B2 (en) | 1997-12-22 | 2011-12-06 | Roche Diagnostics Operations, Inc. | Control and calibration solutions and methods for their use |
| US6893552B1 (en) | 1997-12-29 | 2005-05-17 | Arrowhead Center, Inc. | Microsensors for glucose and insulin monitoring |
| US6134461A (en) | 1998-03-04 | 2000-10-17 | E. Heller & Company | Electrochemical analyte |
| US6391005B1 (en) | 1998-03-30 | 2002-05-21 | Agilent Technologies, Inc. | Apparatus and method for penetration with shaft having a sensor for sensing penetration depth |
| JP4163383B2 (ja) * | 1998-04-14 | 2008-10-08 | カリフォルニア・インスティテュート・オブ・テクノロジー | 検体活性を判定するための方法とシステム |
| US8688188B2 (en) | 1998-04-30 | 2014-04-01 | Abbott Diabetes Care Inc. | Analyte monitoring device and methods of use |
| US8465425B2 (en) | 1998-04-30 | 2013-06-18 | Abbott Diabetes Care Inc. | Analyte monitoring device and methods of use |
| US6949816B2 (en) | 2003-04-21 | 2005-09-27 | Motorola, Inc. | Semiconductor component having first surface area for electrically coupling to a semiconductor chip and second surface area for electrically coupling to a substrate, and method of manufacturing same |
| US8974386B2 (en) | 1998-04-30 | 2015-03-10 | Abbott Diabetes Care Inc. | Analyte monitoring device and methods of use |
| US8480580B2 (en) | 1998-04-30 | 2013-07-09 | Abbott Diabetes Care Inc. | Analyte monitoring device and methods of use |
| US8346337B2 (en) | 1998-04-30 | 2013-01-01 | Abbott Diabetes Care Inc. | Analyte monitoring device and methods of use |
| US9066695B2 (en) | 1998-04-30 | 2015-06-30 | Abbott Diabetes Care Inc. | Analyte monitoring device and methods of use |
| US6175752B1 (en) | 1998-04-30 | 2001-01-16 | Therasense, Inc. | Analyte monitoring device and methods of use |
| US6233471B1 (en) * | 1998-05-13 | 2001-05-15 | Cygnus, Inc. | Signal processing for measurement of physiological analysis |
| JP3600158B2 (ja) * | 1998-05-13 | 2004-12-08 | シグナス, インコーポレイテッド | 生理学的分析物のモニタリング |
| US6294281B1 (en) | 1998-06-17 | 2001-09-25 | Therasense, Inc. | Biological fuel cell and method |
| US6558320B1 (en) * | 2000-01-20 | 2003-05-06 | Medtronic Minimed, Inc. | Handheld personal data assistant (PDA) with a medical device and method of using the same |
| US6248067B1 (en) | 1999-02-05 | 2001-06-19 | Minimed Inc. | Analyte sensor and holter-type monitor system and method of using the same |
| US8394330B1 (en) | 1998-10-02 | 2013-03-12 | The California Institute Of Technology | Conductive organic sensors, arrays and methods of use |
| JP4469504B2 (ja) * | 1998-10-08 | 2010-05-26 | メドトロニック ミニメド インコーポレイテッド | 遠隔形質モニタシステム |
| US6338790B1 (en) | 1998-10-08 | 2002-01-15 | Therasense, Inc. | Small volume in vitro analyte sensor with diffusible or non-leachable redox mediator |
| US7766873B2 (en) | 1998-10-29 | 2010-08-03 | Medtronic Minimed, Inc. | Method and apparatus for detecting occlusions in an ambulatory infusion pump |
| US7621893B2 (en) | 1998-10-29 | 2009-11-24 | Medtronic Minimed, Inc. | Methods and apparatuses for detecting occlusions in an ambulatory infusion pump |
| ATE444481T1 (de) * | 1998-11-16 | 2009-10-15 | California Inst Of Techn | Gleichzeitige bestimmung von gleichgewichts- und kinetischen eigenschaften |
| CA2365609A1 (en) * | 1999-02-12 | 2000-08-17 | Cygnus, Inc. | Devices and methods for frequent measurement of an analyte present in a biological system |
| US6424847B1 (en) | 1999-02-25 | 2002-07-23 | Medtronic Minimed, Inc. | Glucose monitor calibration methods |
| US6360888B1 (en) * | 1999-02-25 | 2002-03-26 | Minimed Inc. | Glucose sensor package system |
| DE60026309T2 (de) * | 1999-05-10 | 2006-12-14 | California Institute Of Technology, Pasadena | Verwendung eines räumlich-zeitlichen reaktionsverhaltens in sensor-arrays zur detektion von analyten in fluiden |
| US6631333B1 (en) * | 1999-05-10 | 2003-10-07 | California Institute Of Technology | Methods for remote characterization of an odor |
| US7122152B2 (en) * | 1999-05-10 | 2006-10-17 | University Of Florida | Spatiotemporal and geometric optimization of sensor arrays for detecting analytes fluids |
| US7806886B2 (en) | 1999-06-03 | 2010-10-05 | Medtronic Minimed, Inc. | Apparatus and method for controlling insulin infusion with state variable feedback |
| WO2000078992A2 (en) | 1999-06-18 | 2000-12-28 | Therasense, Inc. | Mass transport limited in vivo analyte sensor |
| US20020193844A1 (en) * | 1999-07-08 | 2002-12-19 | Michelson Steve A. | Combination electrode-battery assembly for a miniature wireless transcutaneous electrical neuro or muscular-stimulation unit |
| US6914529B2 (en) * | 1999-07-21 | 2005-07-05 | Dow Agrosciences Llc | Sensing devices, systems, and methods particularly for pest control |
| US6890715B1 (en) * | 1999-08-18 | 2005-05-10 | The California Institute Of Technology | Sensors of conducting and insulating composites |
| US20050103624A1 (en) | 1999-10-04 | 2005-05-19 | Bhullar Raghbir S. | Biosensor and method of making |
| US7073246B2 (en) | 1999-10-04 | 2006-07-11 | Roche Diagnostics Operations, Inc. | Method of making a biosensor |
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| US20020139668A1 (en) * | 1999-11-03 | 2002-10-03 | Raghbir Singh Bhullar | Embedded metallic deposits |
| US8444834B2 (en) | 1999-11-15 | 2013-05-21 | Abbott Diabetes Care Inc. | Redox polymers for use in analyte monitoring |
| US8268143B2 (en) * | 1999-11-15 | 2012-09-18 | Abbott Diabetes Care Inc. | Oxygen-effect free analyte sensor |
| US6605201B1 (en) * | 1999-11-15 | 2003-08-12 | Therasense, Inc. | Transition metal complexes with bidentate ligand having an imidazole ring and sensor constructed therewith |
| US6676815B1 (en) * | 1999-12-30 | 2004-01-13 | Roche Diagnostics Corporation | Cell for electrochemical analysis of a sample |
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Also Published As
| Publication number | Publication date |
|---|---|
| JP2015186625A (ja) | 2015-10-29 |
| US8463351B2 (en) | 2013-06-11 |
| JP2002506209A (ja) | 2002-02-26 |
| US20060118415A1 (en) | 2006-06-08 |
| EP1060394B1 (en) | 2017-06-14 |
| WO1999045387A3 (en) | 2000-04-13 |
| US7996054B2 (en) | 2011-08-09 |
| EP2308371A1 (en) | 2011-04-13 |
| US20100204554A1 (en) | 2010-08-12 |
| US8706180B2 (en) | 2014-04-22 |
| JP6395055B2 (ja) | 2018-09-26 |
| US6134461A (en) | 2000-10-17 |
| US7003340B2 (en) | 2006-02-21 |
| US6484046B1 (en) | 2002-11-19 |
| US20100305422A1 (en) | 2010-12-02 |
| EP1060394A2 (en) | 2000-12-20 |
| US20140221801A1 (en) | 2014-08-07 |
| JP2012011208A (ja) | 2012-01-19 |
| AU2465999A (en) | 1999-09-20 |
| US20030088166A1 (en) | 2003-05-08 |
| US20130274574A1 (en) | 2013-10-17 |
| WO1999045387A2 (en) | 1999-09-10 |
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