JP4402173B2 - Ｄｈａ―薬剤複合体 - Google Patents

Ｄｈａ―薬剤複合体 Download PDF

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Publication number
JP4402173B2
JP4402173B2 JP54281197A JP54281197A JP4402173B2 JP 4402173 B2 JP4402173 B2 JP 4402173B2 JP 54281197 A JP54281197 A JP 54281197A JP 54281197 A JP54281197 A JP 54281197A JP 4402173 B2 JP4402173 B2 JP 4402173B2
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Japan
Prior art keywords
hydrochloride
sodium
agent
acid
sulfate
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Expired - Fee Related
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JP54281197A
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Japanese (ja)
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JP2000514405A (ja
JP2000514405A5 (enExample
Inventor
オー． ブラッドレー，マシューズ
イー． シャスア，ビクトール
エル． ウェッブ，ナイジェル
エス． スウィンデル，チャールズ
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ルイトポルド・ファーマシューティカルズ・インコーポレーテッド
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Publication of JP2000514405A5 publication Critical patent/JP2000514405A5/ja
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/542—Carboxylic acids, e.g. a fatty acid or an amino acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

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  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Epoxy Compounds (AREA)
  • Medicinal Preparation (AREA)
JP54281197A 1996-05-22 1997-05-22 Ｄｈａ―薬剤複合体 Expired - Fee Related JP4402173B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/651,312 1996-05-22
US08/651,312 US5795909A (en) 1996-05-22 1996-05-22 DHA-pharmaceutical agent conjugates of taxanes
PCT/US1997/008867 WO1997044063A2 (en) 1996-05-22 1997-05-22 Dha-pharmaceutical agent conjugates

Publications (3)

Publication Number Publication Date
JP2000514405A JP2000514405A (ja) 2000-10-31
JP2000514405A5 JP2000514405A5 (enExample) 2005-02-10
JP4402173B2 true JP4402173B2 (ja) 2010-01-20

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Application Number Title Priority Date Filing Date
JP54281197A Expired - Fee Related JP4402173B2 (ja) 1996-05-22 1997-05-22 Ｄｈａ―薬剤複合体

Country Status (10)

Country Link
US (3) US5795909A (enExample)
EP (2) EP0909183B1 (enExample)
JP (1) JP4402173B2 (enExample)
AT (1) ATE273025T1 (enExample)
AU (1) AU725759B2 (enExample)
CA (1) CA2255614C (enExample)
DE (1) DE69730217T2 (enExample)
DK (1) DK0909183T3 (enExample)
ES (1) ES2222514T3 (enExample)
WO (1) WO1997044063A2 (enExample)

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CA2255614A1 (en) 1997-11-27
EP0909183B1 (en) 2004-08-11
WO1997044063A3 (en) 1998-02-26
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US6602902B2 (en) 2003-08-05
AU725759B2 (en) 2000-10-19
US20020010208A1 (en) 2002-01-24
US7199151B2 (en) 2007-04-03
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US5795909A (en) 1998-08-18
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US20040180949A1 (en) 2004-09-16
JP2000514405A (ja) 2000-10-31
DE69730217D1 (de) 2004-09-16
WO1997044063A2 (en) 1997-11-27
CA2255614C (en) 2009-12-15
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