JP3934673B1 - 修飾組換えワクシニアウイルスおよびその他の微生物、その使用 - Google Patents

修飾組換えワクシニアウイルスおよびその他の微生物、その使用 Download PDF

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JP3934673B1
JP3934673B1 JP2006517504A JP2006517504A JP3934673B1 JP 3934673 B1 JP3934673 B1 JP 3934673B1 JP 2006517504 A JP2006517504 A JP 2006517504A JP 2006517504 A JP2006517504 A JP 2006517504A JP 3934673 B1 JP3934673 B1 JP 3934673B1
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virus
microorganism
gene
tumor
cells
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Expired - Fee Related
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JP2006517504A
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Japanese (ja)
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JP2007524385A (ja
Inventor
アラダル・エイ・サライ
タチアナ・ティミリャソワ
ユ・ヨン・エイ
ジャン・キアン
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Genelux Corp
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Genelux Corp
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Priority claimed from EP03013826A external-priority patent/EP1489164A1/en
Priority claimed from EP03018478A external-priority patent/EP1512746B1/en
Priority claimed from EP03024283A external-priority patent/EP1526185B1/en
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    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/275—Poxviridae, e.g. avipoxvirus
    • A61K39/285—Vaccinia virus or variola virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
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    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
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    • C12N2710/24011—Poxviridae
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JP2006517504A 2003-06-18 2004-06-18 修飾組換えワクシニアウイルスおよびその他の微生物、その使用 Expired - Fee Related JP3934673B1 (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
EP03013826.7 2003-06-18
EP03013826A EP1489164A1 (en) 2003-06-18 2003-06-18 Recombinant vaccinia viruses with modified F3 genes, uses thereof
EP03018478.2 2003-08-14
EP03018478A EP1512746B1 (en) 2003-08-14 2003-08-14 Method for the production of a polypeptide, RNA or other compound in tumor tissue
EP03024283.8 2003-10-22
EP03024283A EP1526185B1 (en) 2003-10-22 2003-10-22 Use of a microorganism or cell to induce autoimmunization of an organism against a tumor
PCT/US2004/019866 WO2005047458A2 (en) 2003-06-18 2004-06-18 Modified recombinant vaccina viruses and other microorganisms, uses thereof

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JP2006287210A Division JP4961190B2 (ja) 2003-06-18 2006-10-23 修飾組換えワクシニアウイルスおよびその他の微生物、その使用

Publications (2)

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JP3934673B1 true JP3934673B1 (ja) 2007-06-20
JP2007524385A JP2007524385A (ja) 2007-08-30

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JP2006517504A Expired - Fee Related JP3934673B1 (ja) 2003-06-18 2004-06-18 修飾組換えワクシニアウイルスおよびその他の微生物、その使用
JP2006287210A Expired - Fee Related JP4961190B2 (ja) 2003-06-18 2006-10-23 修飾組換えワクシニアウイルスおよびその他の微生物、その使用
JP2008017869A Expired - Fee Related JP4294711B2 (ja) 2003-06-18 2008-01-29 修飾組換えワクシニアウイルスおよびその他の微生物、その使用
JP2009136914A Expired - Fee Related JP5342932B2 (ja) 2003-06-18 2009-06-08 修飾組換えワクシニアウイルスおよびその他の微生物、その使用

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JP2006287210A Expired - Fee Related JP4961190B2 (ja) 2003-06-18 2006-10-23 修飾組換えワクシニアウイルスおよびその他の微生物、その使用
JP2008017869A Expired - Fee Related JP4294711B2 (ja) 2003-06-18 2008-01-29 修飾組換えワクシニアウイルスおよびその他の微生物、その使用
JP2009136914A Expired - Fee Related JP5342932B2 (ja) 2003-06-18 2009-06-08 修飾組換えワクシニアウイルスおよびその他の微生物、その使用

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US (11) US7588767B2 (enExample)
EP (2) EP2028270B9 (enExample)
JP (4) JP3934673B1 (enExample)
CN (1) CN100562570C (enExample)
AT (2) ATE545699T1 (enExample)
AU (2) AU2004289953B2 (enExample)
BR (1) BRPI0411526A (enExample)
CA (1) CA2527225C (enExample)
DE (1) DE602004018927D1 (enExample)
MX (1) MXPA05013879A (enExample)
RU (1) RU2376371C2 (enExample)
SG (1) SG179291A1 (enExample)
WO (1) WO2005047458A2 (enExample)

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US20030228261A1 (en) * 2002-06-05 2003-12-11 Aladar Szalay Light emitting microorganisms and cells for diagnosis and therapy of diseases associated with wounded or inflamed tissue
EP1369491A1 (en) 2002-06-05 2003-12-10 Aladar A. Szalay Light emitting microorganisms and cells for diagnosis and therapy of diseases associated with wounded or inflamed tissue
CN1754002B (zh) 2002-08-12 2010-09-08 杰能斯有限公司 涉及痘病毒和癌的组合物及制备方法
BRPI0411526A (pt) * 2003-06-18 2006-08-01 Genelux Corp vìrus de vaccinia e outros microrganismos recombinates modificados e usos dos mesmos
US20070134202A1 (en) * 2003-10-15 2007-06-14 The New Industry Reserch Organization Cancer gene therapeutic drug
US8221739B2 (en) 2004-04-29 2012-07-17 Botanic Oil Innovations, Inc. Method of cancer treatment
JP5489459B2 (ja) 2005-08-01 2014-05-14 ジ・オハイオ・ステイト・ユニバーシティ・リサーチ・ファウンデイション 乳癌の診断、予後及び治療のためのマイクロｒｎａに基づいた方法及び組成物
US8980246B2 (en) 2005-09-07 2015-03-17 Sillajen Biotherapeutics, Inc. Oncolytic vaccinia virus cancer therapy
AU2006287441B2 (en) * 2005-09-07 2012-09-06 Sillajen Biotherapeutics, Inc. Systemic treatment of metastatic and/or systemically-disseminated cancers using GM-CSF-expressing poxviruses
CN101296702B (zh) 2005-09-12 2012-11-28 俄亥俄州立大学研究基金会 用于诊断或治疗bcl2相关癌症的组合物和方法
US20070077231A1 (en) * 2005-09-30 2007-04-05 Contag Christopher H Immune effector cells pre-infected with oncolytic virus
US20070098828A1 (en) * 2005-11-01 2007-05-03 Gonzalez-Villasenor Lucia I Methods and compositions for the prevention and regression of neovascularization
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US8682619B2 (en) * 2005-12-14 2014-03-25 The Invention Science Fund I, Llc Device including altered microorganisms, and methods and systems of use
US8852916B2 (en) 2010-01-22 2014-10-07 The Invention Science Fund I, Llc Compositions and methods for therapeutic delivery with microorganisms
US8734823B2 (en) * 2005-12-14 2014-05-27 The Invention Science Fund I, Llc Device including altered microorganisms, and methods and systems of use
WO2007075879A2 (en) * 2005-12-22 2007-07-05 Memorial Sloan-Kettering Cancer Center Method for detection of cancer cells using virus
WO2007081680A2 (en) 2006-01-05 2007-07-19 The Ohio State University Research Foundation Microrna expression abnormalities in pancreatic endocrine and acinar tumors
ES2536423T3 (es) 2006-01-05 2015-05-25 The Ohio State University Research Foundation Métodos basados en microARN para el diagnóstico de cáncer de próstata
ES2553442T3 (es) 2006-01-05 2015-12-09 The Ohio State University Research Foundation Procedimientos basados en los microARN para el diagnóstico, pronóstico y tratamiento del cáncer de pulmón
EP2369012A1 (en) 2006-03-20 2011-09-28 The Ohio State University Research Foundation Micro-RNA fingerprints during human megakaryocytopoiesis
TW200819540A (en) 2006-07-11 2008-05-01 Genelux Corp Methods and compositions for detection of microorganisms and cells and treatment of diseases and disorders
ES2442890T3 (es) 2006-07-13 2014-02-14 The Ohio State University Research Foundation Métodos y composiciones basados en micro-ARN para el diagnóstico y el tratamiento de enfermedades relacionadas con el colon
ES2374446T3 (es) 2006-09-19 2012-02-16 The Ohio State University Research Foundation Expresión de tcl1 en la leucemia linfocítica crónica (llc) regulada por mir-29 y mir-181.
US8052968B2 (en) * 2006-10-16 2011-11-08 Genelux Corporation Modified vaccinia virus strains for use in diagnostic and therapeutic methods
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