CN100562570C - 修饰的重组痘苗病毒及其它微生物,及其应用 - Google Patents
修饰的重组痘苗病毒及其它微生物,及其应用 Download PDFInfo
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- CN100562570C CN100562570C CNB2004800236108A CN200480023610A CN100562570C CN 100562570 C CN100562570 C CN 100562570C CN B2004800236108 A CNB2004800236108 A CN B2004800236108A CN 200480023610 A CN200480023610 A CN 200480023610A CN 100562570 C CN100562570 C CN 100562570C
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- A61K39/12—Viral antigens
- A61K39/275—Poxviridae, e.g. avipoxvirus
- A61K39/285—Vaccinia virus or variola virus
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- A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
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- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
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- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
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- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
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- C12N2710/24011—Poxviridae
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- C12N2710/24011—Poxviridae
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- C12N2710/24141—Use of virus, viral particle or viral elements as a vector
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- C12N2710/00011—Details
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- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP03013826.7 | 2003-06-18 | ||
| EP03013826A EP1489164A1 (en) | 2003-06-18 | 2003-06-18 | Recombinant vaccinia viruses with modified F3 genes, uses thereof |
| EP03018478.2 | 2003-08-14 | ||
| EP03018478A EP1512746B1 (en) | 2003-08-14 | 2003-08-14 | Method for the production of a polypeptide, RNA or other compound in tumor tissue |
| EP03024283.8 | 2003-10-22 | ||
| EP03024283A EP1526185B1 (en) | 2003-10-22 | 2003-10-22 | Use of a microorganism or cell to induce autoimmunization of an organism against a tumor |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1839201A CN1839201A (zh) | 2006-09-27 |
| CN100562570C true CN100562570C (zh) | 2009-11-25 |
Family
ID=34119412
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB2004800236108A Expired - Lifetime CN100562570C (zh) | 2003-06-18 | 2004-06-18 | 修饰的重组痘苗病毒及其它微生物,及其应用 |
Country Status (13)
| Country | Link |
|---|---|
| US (11) | US7588767B2 (enExample) |
| EP (2) | EP2028270B9 (enExample) |
| JP (4) | JP3934673B1 (enExample) |
| CN (1) | CN100562570C (enExample) |
| AT (2) | ATE545699T1 (enExample) |
| AU (2) | AU2004289953B2 (enExample) |
| BR (1) | BRPI0411526A (enExample) |
| CA (1) | CA2527225C (enExample) |
| DE (1) | DE602004018927D1 (enExample) |
| MX (1) | MXPA05013879A (enExample) |
| RU (1) | RU2376371C2 (enExample) |
| SG (1) | SG179291A1 (enExample) |
| WO (1) | WO2005047458A2 (enExample) |
Families Citing this family (236)
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| EP1281767A3 (en) * | 2001-07-31 | 2003-05-28 | Aladar A. Szalay | Light emitting microorganisms and cells for diagnosis and therapy of tumors |
| US20030228261A1 (en) * | 2002-06-05 | 2003-12-11 | Aladar Szalay | Light emitting microorganisms and cells for diagnosis and therapy of diseases associated with wounded or inflamed tissue |
| EP1369491A1 (en) | 2002-06-05 | 2003-12-10 | Aladar A. Szalay | Light emitting microorganisms and cells for diagnosis and therapy of diseases associated with wounded or inflamed tissue |
| CN1754002B (zh) | 2002-08-12 | 2010-09-08 | 杰能斯有限公司 | 涉及痘病毒和癌的组合物及制备方法 |
| BRPI0411526A (pt) * | 2003-06-18 | 2006-08-01 | Genelux Corp | vìrus de vaccinia e outros microrganismos recombinates modificados e usos dos mesmos |
| US20070134202A1 (en) * | 2003-10-15 | 2007-06-14 | The New Industry Reserch Organization | Cancer gene therapeutic drug |
| US8221739B2 (en) | 2004-04-29 | 2012-07-17 | Botanic Oil Innovations, Inc. | Method of cancer treatment |
| JP5489459B2 (ja) | 2005-08-01 | 2014-05-14 | ジ・オハイオ・ステイト・ユニバーシティ・リサーチ・ファウンデイション | 乳癌の診断、予後及び治療のためのマイクロrnaに基づいた方法及び組成物 |
| US8980246B2 (en) | 2005-09-07 | 2015-03-17 | Sillajen Biotherapeutics, Inc. | Oncolytic vaccinia virus cancer therapy |
| AU2006287441B2 (en) * | 2005-09-07 | 2012-09-06 | Sillajen Biotherapeutics, Inc. | Systemic treatment of metastatic and/or systemically-disseminated cancers using GM-CSF-expressing poxviruses |
| CN101296702B (zh) | 2005-09-12 | 2012-11-28 | 俄亥俄州立大学研究基金会 | 用于诊断或治疗bcl2相关癌症的组合物和方法 |
| US20070077231A1 (en) * | 2005-09-30 | 2007-04-05 | Contag Christopher H | Immune effector cells pre-infected with oncolytic virus |
| US20070098828A1 (en) * | 2005-11-01 | 2007-05-03 | Gonzalez-Villasenor Lucia I | Methods and compositions for the prevention and regression of neovascularization |
| US8278094B2 (en) | 2005-12-14 | 2012-10-02 | The Invention Science Fund I, Llc | Bone semi-permeable device |
| US8682619B2 (en) * | 2005-12-14 | 2014-03-25 | The Invention Science Fund I, Llc | Device including altered microorganisms, and methods and systems of use |
| US8852916B2 (en) | 2010-01-22 | 2014-10-07 | The Invention Science Fund I, Llc | Compositions and methods for therapeutic delivery with microorganisms |
| US8734823B2 (en) * | 2005-12-14 | 2014-05-27 | The Invention Science Fund I, Llc | Device including altered microorganisms, and methods and systems of use |
| WO2007075879A2 (en) * | 2005-12-22 | 2007-07-05 | Memorial Sloan-Kettering Cancer Center | Method for detection of cancer cells using virus |
| WO2007081680A2 (en) | 2006-01-05 | 2007-07-19 | The Ohio State University Research Foundation | Microrna expression abnormalities in pancreatic endocrine and acinar tumors |
| ES2536423T3 (es) | 2006-01-05 | 2015-05-25 | The Ohio State University Research Foundation | Métodos basados en microARN para el diagnóstico de cáncer de próstata |
| ES2553442T3 (es) | 2006-01-05 | 2015-12-09 | The Ohio State University Research Foundation | Procedimientos basados en los microARN para el diagnóstico, pronóstico y tratamiento del cáncer de pulmón |
| EP2369012A1 (en) | 2006-03-20 | 2011-09-28 | The Ohio State University Research Foundation | Micro-RNA fingerprints during human megakaryocytopoiesis |
| TW200819540A (en) | 2006-07-11 | 2008-05-01 | Genelux Corp | Methods and compositions for detection of microorganisms and cells and treatment of diseases and disorders |
| ES2442890T3 (es) | 2006-07-13 | 2014-02-14 | The Ohio State University Research Foundation | Métodos y composiciones basados en micro-ARN para el diagnóstico y el tratamiento de enfermedades relacionadas con el colon |
| ES2374446T3 (es) | 2006-09-19 | 2012-02-16 | The Ohio State University Research Foundation | Expresión de tcl1 en la leucemia linfocítica crónica (llc) regulada por mir-29 y mir-181. |
| US8052968B2 (en) * | 2006-10-16 | 2011-11-08 | Genelux Corporation | Modified vaccinia virus strains for use in diagnostic and therapeutic methods |
| EP2087135B8 (en) | 2006-11-01 | 2013-07-24 | The Ohio State University Research Foundation | Microrna expression signature for predicting survival and metastases in hepatocellular carcinoma |
| CN105256004A (zh) | 2007-01-31 | 2016-01-20 | 俄亥俄州立大学研究基金会 | 用于急性髓细胞白血病(aml)的诊断、预后和治疗的基于微rna的方法和组合物 |
| KR100858913B1 (ko) * | 2007-03-09 | 2008-09-17 | 한국과학기술원 | 부위특이적 변이에 의해 제조된 고수율의 l-쓰레오닌생산균주 및 이를 이용한 l-쓰레오닌의 제조방법 |
| KR20080084528A (ko) * | 2007-03-15 | 2008-09-19 | 제네렉스 바이오테라퓨틱스 인크. | 종양살상형 백시니아 바이러스 암 치료 |
| WO2008141226A2 (en) * | 2007-05-10 | 2008-11-20 | The Arizona Board Of Regents For And On Behalf Of Arizona State University | Recombinant bacteria comprising vectors for expression of nucleic acid sequences encoding antigens |
| WO2009025888A2 (en) | 2007-05-10 | 2009-02-26 | The Arizona Board Of Regents For And On Behalf Of Arizona State University | Regulated synthesis of antigen and/or regulated attentuation to enhance vaccine immunogenics and/or safety |
| US8012738B2 (en) * | 2007-05-14 | 2011-09-06 | Bavarian Nordic A/S | Purification of vaccinia virus- and recombinant vaccinia virus-based vaccines |
| US8003364B2 (en) | 2007-05-14 | 2011-08-23 | Bavarian Nordic A/S | Purification of vaccinia viruses using hydrophobic interaction chromatography |
| WO2008144067A1 (en) * | 2007-05-21 | 2008-11-27 | Board Of Regents, University Of Texas System | Methods and compositions for treatment of cancer using oncolytic rsv activity |
| WO2008150496A2 (en) * | 2007-05-31 | 2008-12-11 | Genelux Corporation | Assay for sensitivity to chemotherapeutic agents |
| ES2537349T3 (es) | 2007-06-08 | 2015-06-05 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Métodos para determinar un subtipo de carcinoma hepatocelular |
| MX2009012924A (es) * | 2007-06-08 | 2010-03-25 | Australian Poultry Crc Pty Ltd | Toxina clostridial netb. |
| WO2008156655A2 (en) | 2007-06-15 | 2008-12-24 | Genelux Corporation | Vaccinia virus vectors encoding a sodium-dependent transporter protein for imaging and/or treatment of tumors |
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