JPS5535004A - Cell-immunity activator and its preparation - Google Patents

Cell-immunity activator and its preparation

Info

Publication number
JPS5535004A
JPS5535004A JP10700878A JP10700878A JPS5535004A JP S5535004 A JPS5535004 A JP S5535004A JP 10700878 A JP10700878 A JP 10700878A JP 10700878 A JP10700878 A JP 10700878A JP S5535004 A JPS5535004 A JP S5535004A
Authority
JP
Japan
Prior art keywords
cell
vaccinia virus
subcultured
tissue culture
activity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP10700878A
Other languages
Japanese (ja)
Other versions
JPS625132B2 (en
Inventor
Seiji Arakawa
Tomio Seki
Shuichi Matsuoka
Hatsunori Harada
Michinari Ninomiya
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
WAKINAGA YAKUHIN KK
Wakunaga Pharmaceutical Co Ltd
Original Assignee
WAKINAGA YAKUHIN KK
Wakunaga Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by WAKINAGA YAKUHIN KK, Wakunaga Pharmaceutical Co Ltd filed Critical WAKINAGA YAKUHIN KK
Priority to JP10700878A priority Critical patent/JPS5535004A/en
Publication of JPS5535004A publication Critical patent/JPS5535004A/en
Publication of JPS625132B2 publication Critical patent/JPS625132B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

PURPOSE: To obtain a cell-immunity activator having anticancinogenic activity, attenuated toxicity and increased cell-immunity activity by the sub culture od vaxcinia virus in a specific medium.
CONSTITUTION: Vaccinia virus (e. g. vaccinia virus Denken No.1 strain, Lister strain, Ikeda strain, etc.) is subcultured in single-layer cells obtained by tissue culture of chicken embryo cells. Or it is subcultured in single-layer cells obtained by tissue culture of kindey cells of a mouse, subsequently transplanted to single- layer cells obtained by tissue culture of chicken embryo cells, and subcultured. Then, the attenuated vaccinia virus thus obtained, is collected by a conventional method, and purified to obtain a cell immunity activator. It has no carcinogenic activity and no affinity to thenerve of the human body and a rabbit, and suppresses the growth of vaccinia virus and malignant tumor.
COPYRIGHT: (C)1980,JPO&Japio
JP10700878A 1978-09-02 1978-09-02 Cell-immunity activator and its preparation Granted JPS5535004A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP10700878A JPS5535004A (en) 1978-09-02 1978-09-02 Cell-immunity activator and its preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP10700878A JPS5535004A (en) 1978-09-02 1978-09-02 Cell-immunity activator and its preparation

Publications (2)

Publication Number Publication Date
JPS5535004A true JPS5535004A (en) 1980-03-11
JPS625132B2 JPS625132B2 (en) 1987-02-03

Family

ID=14448150

Family Applications (1)

Application Number Title Priority Date Filing Date
JP10700878A Granted JPS5535004A (en) 1978-09-02 1978-09-02 Cell-immunity activator and its preparation

Country Status (1)

Country Link
JP (1) JPS5535004A (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5869104A (en) * 1982-05-29 1983-04-25 Nec Corp Parallel operating system for fm modulator
JPS6038328A (en) * 1983-08-11 1985-02-27 Handai Biseibutsubiyou Kenkyukai Method for promoting antineoplastic immunity induction
US9944903B2 (en) 2006-10-16 2018-04-17 Genelux Corporation Modified vaccinia virus strains for use in diagnostic and therapeutic methods
US10463730B2 (en) 2003-06-18 2019-11-05 Genelux Corporation Microorganisms for therapy

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5869104A (en) * 1982-05-29 1983-04-25 Nec Corp Parallel operating system for fm modulator
JPS6038328A (en) * 1983-08-11 1985-02-27 Handai Biseibutsubiyou Kenkyukai Method for promoting antineoplastic immunity induction
US10463730B2 (en) 2003-06-18 2019-11-05 Genelux Corporation Microorganisms for therapy
US9944903B2 (en) 2006-10-16 2018-04-17 Genelux Corporation Modified vaccinia virus strains for use in diagnostic and therapeutic methods
US10584317B2 (en) 2006-10-16 2020-03-10 Genelux Corporation Modified vaccinia virus strains for use in diagnostic and therapeutic methods

Also Published As

Publication number Publication date
JPS625132B2 (en) 1987-02-03

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