JPS579722A - Immunologically active substance and its preparation - Google Patents

Immunologically active substance and its preparation

Info

Publication number
JPS579722A
JPS579722A JP8275380A JP8275380A JPS579722A JP S579722 A JPS579722 A JP S579722A JP 8275380 A JP8275380 A JP 8275380A JP 8275380 A JP8275380 A JP 8275380A JP S579722 A JPS579722 A JP S579722A
Authority
JP
Japan
Prior art keywords
action
substance
culture medium
acinetobacter
water
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP8275380A
Other languages
Japanese (ja)
Inventor
Yoji Suzuki
Shuzo Sawada
Atsushi Imaizumi
Keiji Komoriya
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Teijin Ltd
Original Assignee
Teijin Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teijin Ltd filed Critical Teijin Ltd
Priority to JP8275380A priority Critical patent/JPS579722A/en
Publication of JPS579722A publication Critical patent/JPS579722A/en
Pending legal-status Critical Current

Links

Abstract

NEW MATERIAL:An immunologically active substance, produced by a microorganism belonging to the genus Acinetobacter, readily soluble in water, and insoluble in ethanol, acetone and ether, consisting of 3wt% or less protein and 15wt% or more glucide, and containing substantially no microbial cell component having an endotoxic activity.
USE: An immunological enhancer, expected as a remedy for autoimmune diseases, nephritis, rheumatism, collagen disease, cancer, etc., and having an anticomplementary action, delayed allergenic action and weaker side effects, e.g. blood platelet agglutinating action, and lower acute toxicity than the commercially available lipopolysaccharide medicines.
PROCESS: A microorganism, e.g. Acinetobacter lwoffi TBR No.1 (FERM-P No. 5624), belonging to the genus Acinetobacter is cultivated in a culture medium under aerobic conditions, and a water-soluble substance is collected from the culture medium and extracted to give the aimed substance from the aqueous phase.
COPYRIGHT: (C)1982,JPO&Japio
JP8275380A 1980-06-20 1980-06-20 Immunologically active substance and its preparation Pending JPS579722A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP8275380A JPS579722A (en) 1980-06-20 1980-06-20 Immunologically active substance and its preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP8275380A JPS579722A (en) 1980-06-20 1980-06-20 Immunologically active substance and its preparation

Publications (1)

Publication Number Publication Date
JPS579722A true JPS579722A (en) 1982-01-19

Family

ID=13783191

Family Applications (1)

Application Number Title Priority Date Filing Date
JP8275380A Pending JPS579722A (en) 1980-06-20 1980-06-20 Immunologically active substance and its preparation

Country Status (1)

Country Link
JP (1) JPS579722A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1964570A1 (en) * 2007-03-02 2008-09-03 Bufe, Albrecht, Prof. Dr. med. Pharmaceutical compound to protect against allergies and inflammatory illnesses
US9375444B2 (en) 2008-08-16 2016-06-28 Protectimmun Gmbh Composition for prevention and treatment of allergic and/or inflammatory diseases

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1964570A1 (en) * 2007-03-02 2008-09-03 Bufe, Albrecht, Prof. Dr. med. Pharmaceutical compound to protect against allergies and inflammatory illnesses
US9950017B2 (en) 2007-03-02 2018-04-24 Forschungszentrum Borstel Pharmaceutical composition for protection from allergies and inflammatory disorders
US9375444B2 (en) 2008-08-16 2016-06-28 Protectimmun Gmbh Composition for prevention and treatment of allergic and/or inflammatory diseases

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