JPS579722A - Immunologically active substance and its preparation - Google Patents
Immunologically active substance and its preparationInfo
- Publication number
- JPS579722A JPS579722A JP8275380A JP8275380A JPS579722A JP S579722 A JPS579722 A JP S579722A JP 8275380 A JP8275380 A JP 8275380A JP 8275380 A JP8275380 A JP 8275380A JP S579722 A JPS579722 A JP S579722A
- Authority
- JP
- Japan
- Prior art keywords
- action
- substance
- culture medium
- acinetobacter
- water
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Abstract
NEW MATERIAL:An immunologically active substance, produced by a microorganism belonging to the genus Acinetobacter, readily soluble in water, and insoluble in ethanol, acetone and ether, consisting of 3wt% or less protein and 15wt% or more glucide, and containing substantially no microbial cell component having an endotoxic activity.
USE: An immunological enhancer, expected as a remedy for autoimmune diseases, nephritis, rheumatism, collagen disease, cancer, etc., and having an anticomplementary action, delayed allergenic action and weaker side effects, e.g. blood platelet agglutinating action, and lower acute toxicity than the commercially available lipopolysaccharide medicines.
PROCESS: A microorganism, e.g. Acinetobacter lwoffi TBR No.1 (FERM-P No. 5624), belonging to the genus Acinetobacter is cultivated in a culture medium under aerobic conditions, and a water-soluble substance is collected from the culture medium and extracted to give the aimed substance from the aqueous phase.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP8275380A JPS579722A (en) | 1980-06-20 | 1980-06-20 | Immunologically active substance and its preparation |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP8275380A JPS579722A (en) | 1980-06-20 | 1980-06-20 | Immunologically active substance and its preparation |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS579722A true JPS579722A (en) | 1982-01-19 |
Family
ID=13783191
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP8275380A Pending JPS579722A (en) | 1980-06-20 | 1980-06-20 | Immunologically active substance and its preparation |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS579722A (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1964570A1 (en) * | 2007-03-02 | 2008-09-03 | Bufe, Albrecht, Prof. Dr. med. | Pharmaceutical compound to protect against allergies and inflammatory illnesses |
US9375444B2 (en) | 2008-08-16 | 2016-06-28 | Protectimmun Gmbh | Composition for prevention and treatment of allergic and/or inflammatory diseases |
-
1980
- 1980-06-20 JP JP8275380A patent/JPS579722A/en active Pending
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1964570A1 (en) * | 2007-03-02 | 2008-09-03 | Bufe, Albrecht, Prof. Dr. med. | Pharmaceutical compound to protect against allergies and inflammatory illnesses |
US9950017B2 (en) | 2007-03-02 | 2018-04-24 | Forschungszentrum Borstel | Pharmaceutical composition for protection from allergies and inflammatory disorders |
US9375444B2 (en) | 2008-08-16 | 2016-06-28 | Protectimmun Gmbh | Composition for prevention and treatment of allergic and/or inflammatory diseases |
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