JPS5574797A - Preparation of protein polysaccharide having anti-tumor activity - Google Patents

Preparation of protein polysaccharide having anti-tumor activity

Info

Publication number
JPS5574797A
JPS5574797A JP14982878A JP14982878A JPS5574797A JP S5574797 A JPS5574797 A JP S5574797A JP 14982878 A JP14982878 A JP 14982878A JP 14982878 A JP14982878 A JP 14982878A JP S5574797 A JPS5574797 A JP S5574797A
Authority
JP
Japan
Prior art keywords
tumor activity
reaction
aqueous medium
protein polysaccharide
fruit bodies
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP14982878A
Other languages
Japanese (ja)
Inventor
Hitoshi Ito
Keishiro Shimura
Sensuke Naruse
Inosuke Iwade
Toshiyuki Sai
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mitsubishi Yuka Pharmaceutical Co Ltd
Original Assignee
Mitsubishi Yuka Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mitsubishi Yuka Pharmaceutical Co Ltd filed Critical Mitsubishi Yuka Pharmaceutical Co Ltd
Priority to JP14982878A priority Critical patent/JPS5574797A/en
Publication of JPS5574797A publication Critical patent/JPS5574797A/en
Pending legal-status Critical Current

Links

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  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PURPOSE: To prepare a protein polysaccharide having remarkable anti-tumor activity, by extracting fruit bodies of a novel fungus belonging to Agaricus genus, with an aqueous medium.
CONSTITUTION: Crushed fruit bodies of a novel fungus, Agricus heterosistes Heinem. et Goose (FERM-P No.4731) are extracted with 2W10 times volume of an aqueous medium at 50W100°C for about 1W10 hours. The extract is added with an water-soluble organic solvent such as alcohol or acetone, or with a salt such as calcium chloride. The precipitate is filtered or centrifuged, washed with ether, and dried to obtain the objective substance in powder form. The substance is pale gray powder, and 1% aqueous solution thereof exhibits pH6.0. Color reactions: positive to anthrone sulfate reaction, phenol sulfate reaction, etc.; negative to orcinol reaction.
COPYRIGHT: (C)1980,JPO&Japio
JP14982878A 1978-12-04 1978-12-04 Preparation of protein polysaccharide having anti-tumor activity Pending JPS5574797A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP14982878A JPS5574797A (en) 1978-12-04 1978-12-04 Preparation of protein polysaccharide having anti-tumor activity

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP14982878A JPS5574797A (en) 1978-12-04 1978-12-04 Preparation of protein polysaccharide having anti-tumor activity

Publications (1)

Publication Number Publication Date
JPS5574797A true JPS5574797A (en) 1980-06-05

Family

ID=15483559

Family Applications (1)

Application Number Title Priority Date Filing Date
JP14982878A Pending JPS5574797A (en) 1978-12-04 1978-12-04 Preparation of protein polysaccharide having anti-tumor activity

Country Status (1)

Country Link
JP (1) JPS5574797A (en)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6466127A (en) * 1987-09-07 1989-03-13 Nichirei Kk Antitumor agent
JPH0278630A (en) * 1988-09-14 1990-03-19 Nichirei Corp Antitumor agent
US6093694A (en) * 1996-12-20 2000-07-25 Sumitomo Forestry Co., Ltd. Antitumor active substances
JP2001240603A (en) * 2000-02-29 2001-09-04 Toei Shinyaku Kk beta-1,3-BRANCHED beta-1,6-GLUCAN AND ALKALI EXTRACTED ESSENCE OF AGARICUS MUSHROOM
US6627201B2 (en) 2001-04-03 2003-09-30 Kabushiki Kaisha Sun Chlorella Composition for drinking/eating and beverage/food
CN103070388A (en) * 2013-02-04 2013-05-01 云南茂昽生物科技有限公司 Delicate tricholoma matsutake active extract and preparation method and application thereof

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6466127A (en) * 1987-09-07 1989-03-13 Nichirei Kk Antitumor agent
JPH0278630A (en) * 1988-09-14 1990-03-19 Nichirei Corp Antitumor agent
US6093694A (en) * 1996-12-20 2000-07-25 Sumitomo Forestry Co., Ltd. Antitumor active substances
JP2001240603A (en) * 2000-02-29 2001-09-04 Toei Shinyaku Kk beta-1,3-BRANCHED beta-1,6-GLUCAN AND ALKALI EXTRACTED ESSENCE OF AGARICUS MUSHROOM
US6627201B2 (en) 2001-04-03 2003-09-30 Kabushiki Kaisha Sun Chlorella Composition for drinking/eating and beverage/food
CN103070388A (en) * 2013-02-04 2013-05-01 云南茂昽生物科技有限公司 Delicate tricholoma matsutake active extract and preparation method and application thereof

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