JPS5441315A - Anti-tumor substance and its preparation - Google Patents
Anti-tumor substance and its preparationInfo
- Publication number
- JPS5441315A JPS5441315A JP10609577A JP10609577A JPS5441315A JP S5441315 A JPS5441315 A JP S5441315A JP 10609577 A JP10609577 A JP 10609577A JP 10609577 A JP10609577 A JP 10609577A JP S5441315 A JPS5441315 A JP S5441315A
- Authority
- JP
- Japan
- Prior art keywords
- tumor
- shellfish
- water
- substance
- liver
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Abstract
PURPOSE:To prepare a water-soluble proteinic anti-tumor substance having broad anti-tumor spectrum, high tumorigenesis-inhibiting activity, and high rate of complete recovery, by the separation and purification of a water extract of shellfish after removing the liver therefrom. CONSTITUTION:Liver is removed from shellfish such as turban shell, abalone, pearl oyster, etc., and the flesh of shellfish thus obtained is extracted with an aqueous medium. The extract is subjected to gel-filtration, ultra-filtration, etc. to afford an anti-tumor saccharide-containing protein having an average molecular weight of 10,000-30,000. The characteristics of the substance are as follows: white or slightly yellowish white solid; easily soluble to water; insoluble to organic solvents such as methanol, ethanol, chloroform, acetone, n-haxane, etc.; main peaks of IR spectrum, 1658 and 1550cm<-1>; positive to biuret reaction, xantoprotein reacttion, anthrone sulfuric acid reaction, cysteine sulfuric acid reaction; amphoteric electrolyte.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP10609577A JPS5441315A (en) | 1977-09-02 | 1977-09-02 | Anti-tumor substance and its preparation |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP10609577A JPS5441315A (en) | 1977-09-02 | 1977-09-02 | Anti-tumor substance and its preparation |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS5441315A true JPS5441315A (en) | 1979-04-02 |
Family
ID=14424965
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP10609577A Pending JPS5441315A (en) | 1977-09-02 | 1977-09-02 | Anti-tumor substance and its preparation |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5441315A (en) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS57130918A (en) * | 1981-02-09 | 1982-08-13 | Cosmo Co Ltd | Preparation of antitumor agent |
JPS5927829A (en) * | 1982-08-09 | 1984-02-14 | Cosmo Co Ltd | Antitumor agent and preparation thereof |
KR101217565B1 (en) * | 2010-05-11 | 2013-01-02 | 송선경 | Composition for Enhancing Anti-Cancer Effect or Inhibiting Metastasis of Cancer Comprising Extract of Abalone Viscera |
-
1977
- 1977-09-02 JP JP10609577A patent/JPS5441315A/en active Pending
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS57130918A (en) * | 1981-02-09 | 1982-08-13 | Cosmo Co Ltd | Preparation of antitumor agent |
JPS5927829A (en) * | 1982-08-09 | 1984-02-14 | Cosmo Co Ltd | Antitumor agent and preparation thereof |
JPH0433764B2 (en) * | 1982-08-09 | 1992-06-04 | Cosmo Oil Co Ltd | |
KR101217565B1 (en) * | 2010-05-11 | 2013-01-02 | 송선경 | Composition for Enhancing Anti-Cancer Effect or Inhibiting Metastasis of Cancer Comprising Extract of Abalone Viscera |
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Legal Events
Date | Code | Title | Description |
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A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20040622 |
|
A521 | Written amendment |
Effective date: 20040921 Free format text: JAPANESE INTERMEDIATE CODE: A523 |
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TRDD | Decision of grant or rejection written | ||
A01 | Written decision to grant a patent or to grant a registration (utility model) |
Effective date: 20041116 Free format text: JAPANESE INTERMEDIATE CODE: A01 |
|
A61 | First payment of annual fees (during grant procedure) |
Effective date: 20041214 Free format text: JAPANESE INTERMEDIATE CODE: A61 |
|
R150 | Certificate of patent (=grant) or registration of utility model |
Free format text: JAPANESE INTERMEDIATE CODE: R150 |
|
LAPS | Cancellation because of no payment of annual fees |