JPS5441315A - Anti-tumor substance and its preparation - Google Patents

Anti-tumor substance and its preparation

Info

Publication number
JPS5441315A
JPS5441315A JP10609577A JP10609577A JPS5441315A JP S5441315 A JPS5441315 A JP S5441315A JP 10609577 A JP10609577 A JP 10609577A JP 10609577 A JP10609577 A JP 10609577A JP S5441315 A JPS5441315 A JP S5441315A
Authority
JP
Japan
Prior art keywords
tumor
shellfish
water
substance
liver
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP10609577A
Other languages
Japanese (ja)
Inventor
Takuma Sasaki
Kazuo Nitta
Tomio Takeuchi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Microbial Chemistry Research Foundation
Original Assignee
Microbial Chemistry Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Microbial Chemistry Research Foundation filed Critical Microbial Chemistry Research Foundation
Priority to JP10609577A priority Critical patent/JPS5441315A/en
Publication of JPS5441315A publication Critical patent/JPS5441315A/en
Pending legal-status Critical Current

Links

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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)

Abstract

PURPOSE:To prepare a water-soluble proteinic anti-tumor substance having broad anti-tumor spectrum, high tumorigenesis-inhibiting activity, and high rate of complete recovery, by the separation and purification of a water extract of shellfish after removing the liver therefrom. CONSTITUTION:Liver is removed from shellfish such as turban shell, abalone, pearl oyster, etc., and the flesh of shellfish thus obtained is extracted with an aqueous medium. The extract is subjected to gel-filtration, ultra-filtration, etc. to afford an anti-tumor saccharide-containing protein having an average molecular weight of 10,000-30,000. The characteristics of the substance are as follows: white or slightly yellowish white solid; easily soluble to water; insoluble to organic solvents such as methanol, ethanol, chloroform, acetone, n-haxane, etc.; main peaks of IR spectrum, 1658 and 1550cm<-1>; positive to biuret reaction, xantoprotein reacttion, anthrone sulfuric acid reaction, cysteine sulfuric acid reaction; amphoteric electrolyte.
JP10609577A 1977-09-02 1977-09-02 Anti-tumor substance and its preparation Pending JPS5441315A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP10609577A JPS5441315A (en) 1977-09-02 1977-09-02 Anti-tumor substance and its preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP10609577A JPS5441315A (en) 1977-09-02 1977-09-02 Anti-tumor substance and its preparation

Publications (1)

Publication Number Publication Date
JPS5441315A true JPS5441315A (en) 1979-04-02

Family

ID=14424965

Family Applications (1)

Application Number Title Priority Date Filing Date
JP10609577A Pending JPS5441315A (en) 1977-09-02 1977-09-02 Anti-tumor substance and its preparation

Country Status (1)

Country Link
JP (1) JPS5441315A (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57130918A (en) * 1981-02-09 1982-08-13 Cosmo Co Ltd Preparation of antitumor agent
JPS5927829A (en) * 1982-08-09 1984-02-14 Cosmo Co Ltd Antitumor agent and preparation thereof
KR101217565B1 (en) * 2010-05-11 2013-01-02 송선경 Composition for Enhancing Anti-Cancer Effect or Inhibiting Metastasis of Cancer Comprising Extract of Abalone Viscera

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57130918A (en) * 1981-02-09 1982-08-13 Cosmo Co Ltd Preparation of antitumor agent
JPS5927829A (en) * 1982-08-09 1984-02-14 Cosmo Co Ltd Antitumor agent and preparation thereof
JPH0433764B2 (en) * 1982-08-09 1992-06-04 Cosmo Oil Co Ltd
KR101217565B1 (en) * 2010-05-11 2013-01-02 송선경 Composition for Enhancing Anti-Cancer Effect or Inhibiting Metastasis of Cancer Comprising Extract of Abalone Viscera

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