ES8103974A1 - Pharmaceutical compositions containing climbing ivy extracts - Google Patents
Pharmaceutical compositions containing climbing ivy extractsInfo
- Publication number
- ES8103974A1 ES8103974A1 ES493118A ES493118A ES8103974A1 ES 8103974 A1 ES8103974 A1 ES 8103974A1 ES 493118 A ES493118 A ES 493118A ES 493118 A ES493118 A ES 493118A ES 8103974 A1 ES8103974 A1 ES 8103974A1
- Authority
- ES
- Spain
- Prior art keywords
- extracts
- pharmaceutical compositions
- compositions containing
- climbing ivy
- hederasaponin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000000284 extract Substances 0.000 title abstract 4
- 230000009194 climbing Effects 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 abstract 6
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 abstract 3
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 abstract 2
- RYHDIBJJJRNDSX-MCGLQMIESA-N Hederacoside C Chemical compound O[C@@H]1[C@H](O)[C@@H](O)[C@H](C)O[C@H]1O[C@@H]1[C@@H](CO)O[C@@H](OC[C@@H]2[C@H]([C@H](O)[C@@H](O)[C@H](OC(=O)[C@@]34[C@@H](CC(C)(C)CC3)C=3[C@@]([C@]5(C)CC[C@H]6[C@](C)(CO)[C@@H](O[C@H]7[C@@H]([C@@H](O)[C@@H](O)CO7)O[C@H]7[C@@H]([C@H](O)[C@@H](O)[C@H](C)O7)O)CC[C@]6(C)[C@H]5CC=3)(C)CC4)O2)O)[C@H](O)[C@H]1O RYHDIBJJJRNDSX-MCGLQMIESA-N 0.000 abstract 2
- MLWBUURUTWPMOO-UHFFFAOYSA-N Hederasaponin C Natural products CC1OC(OC2C(O)COC(OC3CCC4(C)C(CCC5(C)C4CC=C6C7CC(C)(C)CCC7(CCC56C)C(=O)OC8OC(COC9OC(CO)C(OC%10OC(C)C(O)C(O)C%10O)C(O)C9O)C(O)C(O)C8O)C3(C)CO)C2O)C(O)C(O)C1O MLWBUURUTWPMOO-UHFFFAOYSA-N 0.000 abstract 2
- RYHDIBJJJRNDSX-UHFFFAOYSA-N kalopanax-saponin B Natural products OC1C(O)C(O)C(C)OC1OC1C(CO)OC(OCC2C(C(O)C(O)C(OC(=O)C34C(CC(C)(C)CC3)C=3C(C5(C)CCC6C(C)(CO)C(OC7C(C(O)C(O)CO7)OC7C(C(O)C(O)C(C)O7)O)CCC6(C)C5CC=3)(C)CC4)O2)O)C(O)C1O RYHDIBJJJRNDSX-UHFFFAOYSA-N 0.000 abstract 2
- 239000007787 solid Substances 0.000 abstract 2
- 241000283690 Bos taurus Species 0.000 abstract 1
- 241000233866 Fungi Species 0.000 abstract 1
- 241000282412 Homo Species 0.000 abstract 1
- 241001465754 Metazoa Species 0.000 abstract 1
- 241001494479 Pecora Species 0.000 abstract 1
- KEOITPILCOILGM-FCWYPSSHSA-N Sapindoside A Natural products O=C(O)[C@]12[C@H](C=3[C@](C)([C@@]4(C)[C@@H]([C@]5(C)[C@H]([C@@](CO)(C)[C@@H](O[C@@H]6[C@@H](O[C@H]7[C@H](O)[C@@H](O)[C@@H](O)[C@H](C)O7)[C@H](O)[C@H](O)CO6)CC5)CC4)CC=3)CC1)CC(C)(C)CC2 KEOITPILCOILGM-FCWYPSSHSA-N 0.000 abstract 1
- KBYYTUYPCGPQNK-UHFFFAOYSA-N alpha-hederin Natural products CC1OC(OC2C(O)C(CO)OC2OC3CCC4(C)C(CCC5(C)C4CC=C6C7CC(C)(C)CCC7(CCC56C)C(=O)O)C3(C)CO)C(O)C(O)C1O KBYYTUYPCGPQNK-UHFFFAOYSA-N 0.000 abstract 1
- PNEYBMLMFCGWSK-UHFFFAOYSA-N aluminium oxide Inorganic materials [O-2].[O-2].[O-2].[Al+3].[Al+3] PNEYBMLMFCGWSK-UHFFFAOYSA-N 0.000 abstract 1
- KEOITPILCOILGM-LLJOFIFVSA-N kalopanaxsaponin A Chemical compound O[C@@H]1[C@H](O)[C@@H](O)[C@H](C)O[C@H]1O[C@H]1[C@H](O[C@@H]2[C@@]([C@H]3[C@]([C@@H]4[C@@]([C@@]5(CC[C@]6(CCC(C)(C)C[C@H]6C5=CC4)C(O)=O)C)(C)CC3)(C)CC2)(C)CO)OC[C@H](O)[C@@H]1O KEOITPILCOILGM-LLJOFIFVSA-N 0.000 abstract 1
- 238000002386 leaching Methods 0.000 abstract 1
- 244000045947 parasite Species 0.000 abstract 1
- 230000001376 precipitating effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/24—Condensed ring systems having three or more rings
- C07H15/256—Polyterpene radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Botany (AREA)
- Pharmacology & Pharmacy (AREA)
- Genetics & Genomics (AREA)
- Alternative & Traditional Medicine (AREA)
- Biochemistry (AREA)
- Medical Informatics (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
Extracts of climbing ivy containing at least 60% of hederasaponin C or comprising alpha-hederin are useful in treating animals (including humans, sheep and cattle) against parasites and fungi. The extracts can be prepared by leaching the ivy with acetone or equivalent, extracting the dried solids with pure methanol, precipitating a solid by adding diethyl ether or equivalent to the methanolic solution and optionally chromatographing the product on alumina with methanol as eluant to increase the hederasaponin C context of the extract.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7917451A FR2460136B1 (en) | 1979-07-05 | 1979-07-05 | PHARMACEUTICAL COMPOSITIONS CONTAINING CLIMBING IVY EXTRACTS |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES8103974A1 true ES8103974A1 (en) | 1981-04-01 |
| ES493118A0 ES493118A0 (en) | 1981-04-01 |
Family
ID=9227547
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES493118A Granted ES493118A0 (en) | 1979-07-05 | 1980-07-04 | PROCEDURE FOR OBTAINING EXTRACTS FROM TREPADORA IVY |
Country Status (13)
| Country | Link |
|---|---|
| AT (1) | AT369264B (en) |
| BE (1) | BE884190A (en) |
| CH (1) | CH647787A5 (en) |
| DE (1) | DE3025223A1 (en) |
| ES (1) | ES493118A0 (en) |
| FR (1) | FR2460136B1 (en) |
| GB (1) | GB2051575B (en) |
| GR (1) | GR69637B (en) |
| IE (1) | IE50062B1 (en) |
| IT (1) | IT1132510B (en) |
| LU (1) | LU82583A1 (en) |
| NL (1) | NL8003871A (en) |
| PT (1) | PT71495A (en) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1195849B (en) * | 1986-07-01 | 1988-10-27 | Sigma Tau Ind Farmaceuti | TRITERPENIC SOAPS WITH ANTI-INFLAMMATORY, MUCOLITIC AND ANTI-EDEMIGEN ACTIVITY, PROCEDURE FOR THEIR OBTAINING AND PHARMACEUTICAL COMPOSITIONS THAT INCLUDE THEM |
| DE4010042A1 (en) * | 1990-03-29 | 1991-10-24 | Cassella Ag | USE OF IVY FOR TOPICAL TREATMENT OF INCREASED SCALING OF HAIRY AND HAIRLESS SKIN AND PSORIASIS |
| WO2004089357A2 (en) * | 2003-04-02 | 2004-10-21 | Regents Of The University Of Minnesota | Anti-fungal formulation of triterpene and essential oil |
| DE10335173A1 (en) * | 2003-07-30 | 2005-03-03 | Mirjana Kiener | Means for enlarging the female breast |
| DE10345343A1 (en) | 2003-09-19 | 2005-04-14 | Engelhard Arzneimittel Gmbh & Co. Kg | Production of an ivy leaf extract with both rapid and prolonged action in treating respiratory diseases, comprises mixing a first ivy extract rich in hederacoside C with a second ivy extract rich in alpha-hederin |
| DE10345342A1 (en) * | 2003-09-19 | 2005-04-28 | Engelhard Arzneimittel Gmbh | Producing an ivy leaf extract containing hederacoside C and alpha-hederin, useful for treating respiratory diseases comprises steaming comminuted ivy leaves before extraction |
| GB0724967D0 (en) * | 2007-12-21 | 2008-01-30 | Univ Bangor | Composition and method |
| GB201404505D0 (en) * | 2013-09-06 | 2014-04-30 | Mars Inc | Oral anti-parasitic composition |
| EP3939596A1 (en) | 2020-07-14 | 2022-01-19 | Bimeda Animal Health Limited | A composition for treating helminth infestation in a mammal |
| CN114805466B (en) * | 2022-04-15 | 2023-06-20 | 湖南朗林生物资源股份有限公司 | Preparation method of hedera helix extract |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR6330E (en) * | 1905-06-14 | 1906-10-13 | Petrus Johannes Portman | Automatic device with control device for the safety of railway traffic |
| BE670523A (en) * | 1964-10-09 | |||
| FR6218M (en) * | 1967-05-24 | 1968-07-29 | ||
| FR2233071A1 (en) * | 1973-06-14 | 1975-01-10 | Prod Hyg Laboratoires | Flavones and saponins extracted from ivy - by solid-liquid extraction of undesirables followed by alcohol extraction |
-
1979
- 1979-07-05 FR FR7917451A patent/FR2460136B1/en not_active Expired
-
1980
- 1980-07-03 DE DE19803025223 patent/DE3025223A1/en not_active Withdrawn
- 1980-07-04 NL NL8003871A patent/NL8003871A/en not_active Application Discontinuation
- 1980-07-04 IT IT23262/80A patent/IT1132510B/en active
- 1980-07-04 IE IE1393/80A patent/IE50062B1/en unknown
- 1980-07-04 AT AT0350580A patent/AT369264B/en not_active IP Right Cessation
- 1980-07-04 PT PT71495A patent/PT71495A/en unknown
- 1980-07-04 GR GR62377A patent/GR69637B/el unknown
- 1980-07-04 CH CH5153/80A patent/CH647787A5/en not_active IP Right Cessation
- 1980-07-04 BE BE0/201310A patent/BE884190A/en not_active IP Right Cessation
- 1980-07-04 ES ES493118A patent/ES493118A0/en active Granted
- 1980-07-04 GB GB8021943A patent/GB2051575B/en not_active Expired
- 1980-07-04 LU LU82583A patent/LU82583A1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IT8023262A0 (en) | 1980-07-04 |
| NL8003871A (en) | 1981-01-07 |
| ATA350580A (en) | 1982-05-15 |
| GR69637B (en) | 1982-07-06 |
| FR2460136B1 (en) | 1986-01-10 |
| FR2460136A1 (en) | 1981-01-23 |
| CH647787A5 (en) | 1985-02-15 |
| BE884190A (en) | 1981-01-05 |
| IT1132510B (en) | 1986-07-02 |
| GB2051575B (en) | 1984-01-18 |
| ES493118A0 (en) | 1981-04-01 |
| DE3025223A1 (en) | 1981-01-08 |
| IE50062B1 (en) | 1986-02-05 |
| IE801393L (en) | 1981-01-05 |
| GB2051575A (en) | 1981-01-21 |
| AT369264B (en) | 1982-12-27 |
| LU82583A1 (en) | 1980-10-08 |
| PT71495A (en) | 1980-08-01 |
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