JPS56103194A - Antitumor substance and its preparation - Google Patents

Antitumor substance and its preparation

Info

Publication number
JPS56103194A
JPS56103194A JP578480A JP578480A JPS56103194A JP S56103194 A JPS56103194 A JP S56103194A JP 578480 A JP578480 A JP 578480A JP 578480 A JP578480 A JP 578480A JP S56103194 A JPS56103194 A JP S56103194A
Authority
JP
Japan
Prior art keywords
extracted
give
substance
antitumor
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP578480A
Other languages
Japanese (ja)
Inventor
Harutaro Yasuda
Takashi Adachi
Toshio Takizawa
Shingo Uchida
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Meiji Seika Kaisha Ltd
Original Assignee
Meiji Seika Kaisha Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Meiji Seika Kaisha Ltd filed Critical Meiji Seika Kaisha Ltd
Priority to JP578480A priority Critical patent/JPS56103194A/en
Publication of JPS56103194A publication Critical patent/JPS56103194A/en
Pending legal-status Critical Current

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Landscapes

  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)

Abstract

NEW MATERIAL:An antitumor substance CW-5. Elementary analysis(%): C, 46.25; H, 5.99; N, 7.69. Ash content: 1.5% or less. Infrared absorption: Substantially as shown in the figure; 1,650cm-1, 1,080cm-1 and 2920cm-1. Solubility: Insoluble in water and organic solvents. Amino acid analysis: (decreasing order of contents): glutamic acid, alanine, asparagine, leucine, lysine, etc. Saccharide composition: galactose, glucose, ribose and glucosamine.
USE: An antitumor agent effective for inhibiting tumor in a dose of 100W0.01mg/ kg.
PROCESS: A strain, e.g. Bifidobacterium longum M101-2, FERM-P No.5356, belonging to the genus Bifidobacterium, is cultivated to give a microbial cell, which is defatted, destroyed and extracted with a nonionic surfactant, e.g. Triton X-100 and then extracted with an anionic surfactant solution. The resultant extract is deproteinized to give the titled substance.
COPYRIGHT: (C)1981,JPO&Japio
JP578480A 1980-01-23 1980-01-23 Antitumor substance and its preparation Pending JPS56103194A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP578480A JPS56103194A (en) 1980-01-23 1980-01-23 Antitumor substance and its preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP578480A JPS56103194A (en) 1980-01-23 1980-01-23 Antitumor substance and its preparation

Publications (1)

Publication Number Publication Date
JPS56103194A true JPS56103194A (en) 1981-08-18

Family

ID=11620726

Family Applications (1)

Application Number Title Priority Date Filing Date
JP578480A Pending JPS56103194A (en) 1980-01-23 1980-01-23 Antitumor substance and its preparation

Country Status (1)

Country Link
JP (1) JPS56103194A (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57212122A (en) * 1981-06-24 1982-12-27 Morinaga Milk Ind Co Ltd Antitumor agent and its preparation
EP0116232A2 (en) * 1982-12-27 1984-08-22 Morinaga Milk Industry Co., Ltd. Antitumor agent and process for manufacturing said agent
EP0201332A2 (en) * 1985-05-09 1986-11-12 Morinaga Milk Industry Co., Ltd. A substance having an anti-infective activity
GR900100706A (en) * 1989-09-29 1992-01-20 Om Lab Sa Extracellulr exopolymer process for its preparation and pharmaceutical compositions containing the said exopolymer

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57212122A (en) * 1981-06-24 1982-12-27 Morinaga Milk Ind Co Ltd Antitumor agent and its preparation
JPS637530B2 (en) * 1981-06-24 1988-02-17 Morinaga Milk Industry Co Ltd
EP0116232A2 (en) * 1982-12-27 1984-08-22 Morinaga Milk Industry Co., Ltd. Antitumor agent and process for manufacturing said agent
EP0201332A2 (en) * 1985-05-09 1986-11-12 Morinaga Milk Industry Co., Ltd. A substance having an anti-infective activity
GR900100706A (en) * 1989-09-29 1992-01-20 Om Lab Sa Extracellulr exopolymer process for its preparation and pharmaceutical compositions containing the said exopolymer
TR25353A (en) * 1989-09-29 1993-03-01 Om Lab Sa PROCESS FOR THE PREPARATION OF A EXTRACELLULAR EXKSOLIMER

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