JPS56103194A - Antitumor substance and its preparation - Google Patents
Antitumor substance and its preparationInfo
- Publication number
- JPS56103194A JPS56103194A JP578480A JP578480A JPS56103194A JP S56103194 A JPS56103194 A JP S56103194A JP 578480 A JP578480 A JP 578480A JP 578480 A JP578480 A JP 578480A JP S56103194 A JPS56103194 A JP S56103194A
- Authority
- JP
- Japan
- Prior art keywords
- extracted
- give
- substance
- antitumor
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Abstract
NEW MATERIAL:An antitumor substance CW-5. Elementary analysis(%): C, 46.25; H, 5.99; N, 7.69. Ash content: 1.5% or less. Infrared absorption: Substantially as shown in the figure; 1,650cm-1, 1,080cm-1 and 2920cm-1. Solubility: Insoluble in water and organic solvents. Amino acid analysis: (decreasing order of contents): glutamic acid, alanine, asparagine, leucine, lysine, etc. Saccharide composition: galactose, glucose, ribose and glucosamine.
USE: An antitumor agent effective for inhibiting tumor in a dose of 100W0.01mg/ kg.
PROCESS: A strain, e.g. Bifidobacterium longum M101-2, FERM-P No.5356, belonging to the genus Bifidobacterium, is cultivated to give a microbial cell, which is defatted, destroyed and extracted with a nonionic surfactant, e.g. Triton X-100 and then extracted with an anionic surfactant solution. The resultant extract is deproteinized to give the titled substance.
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP578480A JPS56103194A (en) | 1980-01-23 | 1980-01-23 | Antitumor substance and its preparation |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP578480A JPS56103194A (en) | 1980-01-23 | 1980-01-23 | Antitumor substance and its preparation |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS56103194A true JPS56103194A (en) | 1981-08-18 |
Family
ID=11620726
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP578480A Pending JPS56103194A (en) | 1980-01-23 | 1980-01-23 | Antitumor substance and its preparation |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS56103194A (en) |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS57212122A (en) * | 1981-06-24 | 1982-12-27 | Morinaga Milk Ind Co Ltd | Antitumor agent and its preparation |
EP0116232A2 (en) * | 1982-12-27 | 1984-08-22 | Morinaga Milk Industry Co., Ltd. | Antitumor agent and process for manufacturing said agent |
EP0201332A2 (en) * | 1985-05-09 | 1986-11-12 | Morinaga Milk Industry Co., Ltd. | A substance having an anti-infective activity |
GR900100706A (en) * | 1989-09-29 | 1992-01-20 | Om Lab Sa | Extracellulr exopolymer process for its preparation and pharmaceutical compositions containing the said exopolymer |
-
1980
- 1980-01-23 JP JP578480A patent/JPS56103194A/en active Pending
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS57212122A (en) * | 1981-06-24 | 1982-12-27 | Morinaga Milk Ind Co Ltd | Antitumor agent and its preparation |
JPS637530B2 (en) * | 1981-06-24 | 1988-02-17 | Morinaga Milk Industry Co Ltd | |
EP0116232A2 (en) * | 1982-12-27 | 1984-08-22 | Morinaga Milk Industry Co., Ltd. | Antitumor agent and process for manufacturing said agent |
EP0201332A2 (en) * | 1985-05-09 | 1986-11-12 | Morinaga Milk Industry Co., Ltd. | A substance having an anti-infective activity |
GR900100706A (en) * | 1989-09-29 | 1992-01-20 | Om Lab Sa | Extracellulr exopolymer process for its preparation and pharmaceutical compositions containing the said exopolymer |
TR25353A (en) * | 1989-09-29 | 1993-03-01 | Om Lab Sa | PROCESS FOR THE PREPARATION OF A EXTRACELLULAR EXKSOLIMER |
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