|
WO2009030254A1
(en)
*
|
2007-09-04 |
2009-03-12 |
Curevac Gmbh |
Complexes of rna and cationic peptides for transfection and for immunostimulation
|
|
PL2591114T3
(pl)
|
2010-07-06 |
2017-08-31 |
Glaxosmithkline Biologicals Sa |
Immunizacja dużych ssaków małymi dawkami rna
|
|
HUE047796T2
(hu)
|
2010-07-06 |
2020-05-28 |
Glaxosmithkline Biologicals Sa |
RNS bevitele több immunútvonal bekapcsolására
|
|
HUE026646T2
(en)
|
2010-07-06 |
2016-07-28 |
Glaxosmithkline Biologicals Sa |
Preferred liposomes containing lipids of PKA value for delivery of RNA
|
|
PT3970742T
(pt)
|
2010-08-31 |
2022-06-27 |
Glaxosmithkline Biologicals Sa |
Lipossomas peguilados para entrega de arn codificador de imunogénio
|
|
JP2013544504A
(ja)
|
2010-10-11 |
2013-12-19 |
ノバルティス アーゲー |
抗原送達プラットフォーム
|
|
WO2013006838A1
(en)
|
2011-07-06 |
2013-01-10 |
Novartis Ag |
Immunogenic combination compositions and uses thereof
|
|
US9464124B2
(en)
|
2011-09-12 |
2016-10-11 |
Moderna Therapeutics, Inc. |
Engineered nucleic acids and methods of use thereof
|
|
JP2016538829A
(ja)
|
2013-10-03 |
2016-12-15 |
モデルナ セラピューティクス インコーポレイテッドＭｏｄｅｒｎａ Ｔｈｅｒａｐｅｕｔｉｃｓ，Ｉｎｃ． |
低密度リポタンパク質受容体をコードするポリヌクレオチド
|
|
SG10201912038TA
(en)
|
2014-04-23 |
2020-02-27 |
Modernatx Inc |
Nucleic acid vaccines
|
|
SMT202200502T1
(it)
|
2014-06-25 |
2023-01-13 |
Acuitas Therapeutics Inc |
Nuovi lipidi e formulazioni di nanoparticelle lipidiche per l'erogazione di acidi nucleici
|
|
EP4578865A3
(en)
|
2014-08-12 |
2025-07-30 |
Monash University |
Lymph directing prodrugs
|
|
EP3283059B1
(en)
|
2015-04-13 |
2024-01-03 |
CureVac Manufacturing GmbH |
Method for producing rna compositions
|
|
US20180303925A1
(en)
|
2015-04-27 |
2018-10-25 |
The Trustees Of The University Of Pennsylvania |
Nucleoside-Modified RNA For Inducing an Adaptive Immune Response
|
|
LT3313829T
(lt)
|
2015-06-29 |
2024-08-12 |
Acuitas Therapeutics Inc. |
Lipidai ir lipidų nanodalelių sudėtys, skirtos nukleorūgščių tiekimui
|
|
EP3324979B1
(en)
|
2015-07-21 |
2022-10-12 |
ModernaTX, Inc. |
Infectious disease vaccines
|
|
US11364292B2
(en)
|
2015-07-21 |
2022-06-21 |
Modernatx, Inc. |
CHIKV RNA vaccines
|
|
WO2017020026A1
(en)
|
2015-07-30 |
2017-02-02 |
Modernatx, Inc. |
Concatemeric peptide epitopes rnas
|
|
WO2017031232A1
(en)
|
2015-08-17 |
2017-02-23 |
Modernatx, Inc. |
Methods for preparing particles and related compositions
|
|
CA2997106C
(en)
|
2015-09-08 |
2024-06-04 |
Monash University |
Lymph directing prodrugs
|
|
EP4286012A3
(en)
*
|
2015-09-17 |
2024-05-29 |
ModernaTX, Inc. |
Compounds and compositions for intracellular delivery of therapeutic agents
|
|
EP3364950A4
(en)
|
2015-10-22 |
2019-10-23 |
ModernaTX, Inc. |
VACCINES AGAINST TROPICAL DISEASES
|
|
CA3002912A1
(en)
|
2015-10-22 |
2017-04-27 |
Modernatx, Inc. |
Nucleic acid vaccines for varicella zoster virus (vzv)
|
|
EP3364981A4
(en)
*
|
2015-10-22 |
2019-08-07 |
ModernaTX, Inc. |
VACCINE AGAINST THE HUMAN CYTOMEGALOVIRUS
|
|
US20180289792A1
(en)
|
2015-10-22 |
2018-10-11 |
ModernaTX. Inc. |
Sexually transmitted disease vaccines
|
|
EP3364949A4
(en)
|
2015-10-22 |
2019-07-31 |
ModernaTX, Inc. |
CANCER VACCINES
|
|
TW201729835A
(zh)
|
2015-10-22 |
2017-09-01 |
現代公司 |
呼吸道病毒疫苗
|
|
IL307179A
(en)
|
2015-10-28 |
2023-11-01 |
Acuitas Therapeutics Inc |
Novel lipids and lipid nanoparticle formulations for delivery of nucleic acids
|
|
HRP20220652T1
(hr)
|
2015-12-10 |
2022-06-24 |
Modernatx, Inc. |
Pripravci i postupci unosa terapijskih sredstava
|
|
MA43568A
(fr)
*
|
2015-12-17 |
2018-11-14 |
Modernatx Inc |
Polynucléotides codant pour la méthylmalonyl-coa mutase
|
|
HUE057877T2
(hu)
|
2015-12-22 |
2022-06-28 |
Modernatx Inc |
Vegyületek és készítmények terápiás szerek intracelluláris bejuttatására
|
|
US10465190B1
(en)
|
2015-12-23 |
2019-11-05 |
Modernatx, Inc. |
In vitro transcription methods and constructs
|
|
WO2017201348A1
(en)
|
2016-05-18 |
2017-11-23 |
Modernatx, Inc. |
Polynucleotides encoding galactose-1-phosphate uridylyltransferase for the treatment of galactosemia type 1
|
|
MA45052A
(fr)
|
2016-05-18 |
2019-03-27 |
Modernatx Inc |
Polynucléotides codant pour jagged1 pour le traitement du syndrome d'alagille
|
|
US20190298657A1
(en)
*
|
2016-05-18 |
2019-10-03 |
Modernatx, Inc. |
Polynucleotides Encoding Acyl-CoA Dehydrogenase, Very Long-Chain for the Treatment of Very Long-Chain Acyl-CoA Dehydrogenase Deficiency
|
|
KR20230074598A
(ko)
|
2016-05-18 |
2023-05-30 |
모더나티엑스, 인크. |
릴랙신을 인코딩하는 폴리뉴클레오타이드
|
|
MA45032A
(fr)
|
2016-05-18 |
2019-03-27 |
Fundacion Para La Investig Medica Aplicada |
Polynucléotides codant pour la porphobilinogène désaminase destinés au traitement de la porphyrie intermittente aiguë
|
|
AU2017266932B2
(en)
*
|
2016-05-18 |
2023-04-20 |
Modernatx, Inc. |
Polynucleotides encoding alpha-galactosidase A for the treatment of Fabry disease
|
|
KR102469450B1
(ko)
|
2016-05-18 |
2022-11-22 |
모더나티엑스, 인크. |
인터류킨-12 (il12)를 코딩하는 폴리뉴클레오티드 및 그의 용도
|
|
EP3458106A4
(en)
*
|
2016-05-18 |
2020-03-18 |
Modernatx, Inc. |
POLYNUCLEOTIDS FOR CODING LIPOPROTEIN LIPASE FOR TREATING HYPERLIPIDEMIA
|
|
MA45036A
(fr)
|
2016-05-18 |
2019-03-27 |
Modernatx Inc |
Polynucléotides codant pour la citrine pour le traitement de la citrullinémie de type 2
|
|
WO2017201347A1
(en)
*
|
2016-05-18 |
2017-11-23 |
Modernatx, Inc. |
Polynucleotides encoding cystic fibrosis transmembrane conductance regulator for the treatment of cystic fibrosis
|
|
CN109790207B
(zh)
|
2016-06-07 |
2023-06-20 |
摩登纳特斯有限公司 |
编码vegf-a多肽的经修饰的rna、配制品和关于它们的用途
|
|
CN116837052A
(zh)
|
2016-09-14 |
2023-10-03 |
摩登纳特斯有限公司 |
高纯度rna组合物及其制备方法
|
|
MA46584A
(fr)
|
2016-10-21 |
2019-08-28 |
Modernatx Inc |
Vaccin contre le cytomégalovirus humain
|
|
BR112019008481A2
(pt)
*
|
2016-10-26 |
2020-03-03 |
Curevac Ag |
Vacinas de mrna de nanopartículas lipídicas
|
|
US12491261B2
(en)
|
2016-10-26 |
2025-12-09 |
Acuitas Therapeutics, Inc. |
Lipid nanoparticle formulations
|
|
US11583504B2
(en)
|
2016-11-08 |
2023-02-21 |
Modernatx, Inc. |
Stabilized formulations of lipid nanoparticles
|
|
WO2018089851A2
(en)
|
2016-11-11 |
2018-05-17 |
Modernatx, Inc. |
Influenza vaccine
|
|
WO2018107088A2
(en)
*
|
2016-12-08 |
2018-06-14 |
Modernatx, Inc. |
Respiratory virus nucleic acid vaccines
|
|
WO2018111967A1
(en)
|
2016-12-13 |
2018-06-21 |
Modernatx, Inc. |
Rna affinity purification
|
|
WO2018115525A1
(en)
*
|
2016-12-23 |
2018-06-28 |
Curevac Ag |
Lassa virus vaccine
|
|
WO2018132537A1
(en)
|
2017-01-11 |
2018-07-19 |
The Trustees Of The University Of Pennsylvania |
Nucleoside-modified rna for inducing an immune response against zika virus
|
|
JP2020514321A
(ja)
*
|
2017-02-01 |
2020-05-21 |
モデルナティーエックス， インコーポレイテッド |
活性化がん遺伝子変異ペプチドをコードする免疫調節治療ｍＲＮＡ組成物
|
|
WO2018151816A1
(en)
|
2017-02-16 |
2018-08-23 |
Modernatx, Inc. |
High potency immunogenic compositions
|
|
US11752206B2
(en)
*
|
2017-03-15 |
2023-09-12 |
Modernatx, Inc. |
Herpes simplex virus vaccine
|
|
WO2018170245A1
(en)
|
2017-03-15 |
2018-09-20 |
Modernatx, Inc. |
Broad spectrum influenza virus vaccine
|
|
EP3595713A4
(en)
*
|
2017-03-15 |
2021-01-13 |
ModernaTX, Inc. |
RESPIRATORY SYNCYTIAL VIRUS Vaccine
|
|
WO2018170322A1
(en)
|
2017-03-15 |
2018-09-20 |
Modernatx, Inc. |
Crystal forms of amino lipids
|
|
US11045540B2
(en)
|
2017-03-15 |
2021-06-29 |
Modernatx, Inc. |
Varicella zoster virus (VZV) vaccine
|
|
SMT202300097T1
(it)
*
|
2017-03-15 |
2023-05-12 |
Modernatx Inc |
Composto e composizioni per il rilascio intracellulare di agenti terapeutici
|
|
US11969506B2
(en)
|
2017-03-15 |
2024-04-30 |
Modernatx, Inc. |
Lipid nanoparticle formulation
|
|
MA47790A
(fr)
|
2017-03-17 |
2021-05-05 |
Modernatx Inc |
Vaccins à base d'arn contre des maladies zoonotiques
|
|
WO2018187590A1
(en)
*
|
2017-04-05 |
2018-10-11 |
Modernatx, Inc. |
Reduction or elimination of immune responses to non-intravenous, e.g., subcutaneously administered therapeutic proteins
|
|
WO2018191657A1
(en)
|
2017-04-13 |
2018-10-18 |
Acuitas Therapeutics, Inc. |
Lipids for delivery of active agents
|
|
MA49463A
(fr)
*
|
2017-04-26 |
2021-05-05 |
Modernatx Inc |
Vaccin contre le virus de l'herpès simplex
|
|
JP7464954B2
(ja)
|
2017-04-27 |
2024-04-10 |
ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア |
Ｃ型肝炎ウイルスに対するヌクレオシド修飾ｍＲＮＡ－脂質ナノ粒子系統ワクチン
|
|
WO2018200943A1
(en)
*
|
2017-04-28 |
2018-11-01 |
Acuitas Therapeutics, Inc. |
Novel carbonyl lipids and lipid nanoparticle formulations for delivery of nucleic acids
|
|
MX2019013752A
(es)
|
2017-05-16 |
2020-07-20 |
Translate Bio Inc |
Tratamiento de la fibrosis quística mediante el suministro de arnm que codifica cftr optimizado en codones.
|
|
JP7285220B2
(ja)
|
2017-05-18 |
2023-06-01 |
モデルナティエックス インコーポレイテッド |
連結したインターロイキン－１２（ｉｌ１２）ポリペプチドをコードするポリヌクレオチドを含む脂質ナノ粒子
|
|
WO2018225871A1
(ja)
*
|
2017-06-09 |
2018-12-13 |
協和発酵キリン株式会社 |
カチオン性脂質としての化合物
|
|
US12077501B2
(en)
|
2017-06-14 |
2024-09-03 |
Modernatx, Inc. |
Compounds and compositions for intracellular delivery of agents
|
|
EP3638292A1
(en)
*
|
2017-06-14 |
2020-04-22 |
ModernaTX, Inc. |
Polynucleotides encoding coagulation factor viii
|
|
US11786607B2
(en)
|
2017-06-15 |
2023-10-17 |
Modernatx, Inc. |
RNA formulations
|
|
EP3641834B1
(en)
|
2017-06-19 |
2023-10-04 |
Translate Bio, Inc. |
Messenger rna therapy for the treatment of friedreich's ataxia
|
|
WO2019002889A1
(en)
|
2017-06-30 |
2019-01-03 |
Industrial Technology Research Institute |
METHOD FOR TREATING AUTOIMMUNE NEUROLOGICAL DISEASE AND / OR NEURODEGENERATIVE DISEASE AND PHARMACEUTICAL FORMULAS FOR LIQUID GALENIC FORM AND CONTROLLED RELEASE GALENIC FORM
|
|
EP3662913A4
(en)
*
|
2017-08-04 |
2021-06-30 |
Kyowa Kirin Co., Ltd. |
Nucleic-acid-containing lipid nanoparticles
|
|
CA3073020A1
(en)
|
2017-08-16 |
2019-02-21 |
Acuitas Therapeutics, Inc. |
Lipids for use in lipid nanoparticle formulations
|
|
WO2019036028A1
(en)
|
2017-08-17 |
2019-02-21 |
Acuitas Therapeutics, Inc. |
LIPIDS FOR USE IN LIPID NANOPARTICULAR FORMULATIONS
|
|
EP3668834B1
(en)
|
2017-08-17 |
2024-10-02 |
Acuitas Therapeutics, Inc. |
Lipids for use in lipid nanoparticle formulations
|
|
US11524932B2
(en)
|
2017-08-17 |
2022-12-13 |
Acuitas Therapeutics, Inc. |
Lipids for use in lipid nanoparticle formulations
|
|
MA50751A
(fr)
|
2017-08-18 |
2020-06-24 |
Modernatx Inc |
Vaccins à base d'arnm efficaces
|
|
ES2983060T3
(es)
|
2017-08-18 |
2024-10-21 |
Modernatx Inc |
Variantes de ARN polimerasa
|
|
WO2019036683A1
(en)
|
2017-08-18 |
2019-02-21 |
Modernatx, Inc. |
ANALYTICAL METHODS BY HPLC
|
|
WO2019036685A1
(en)
|
2017-08-18 |
2019-02-21 |
Modernatx, Inc. |
METHODS FOR HPLC ANALYSIS
|
|
US11883497B2
(en)
|
2017-08-29 |
2024-01-30 |
Puretech Lyt, Inc. |
Lymphatic system-directing lipid prodrugs
|
|
EP3675838A4
(en)
|
2017-08-29 |
2021-04-21 |
PureTech LYT, Inc. |
LIPID PRODRUGS DIRECTED TO THE LYMPHATIC SYSTEM
|
|
WO2019046809A1
(en)
|
2017-08-31 |
2019-03-07 |
Modernatx, Inc. |
METHODS OF MANUFACTURING LIPID NANOPARTICLES
|
|
EP3681514A4
(en)
|
2017-09-14 |
2021-07-14 |
ModernaTX, Inc. |
RNA VACZINE AGAINST ZIKA VIRUS
|
|
CA3080592A1
(en)
*
|
2017-10-31 |
2019-05-09 |
Modernatx, Inc. |
Lipid nanoparticles for delivering modified rna encoding a vegf-a polypeptide
|
|
JP7423521B2
(ja)
*
|
2017-11-22 |
2024-01-29 |
モダーナティエックス・インコーポレイテッド |
フェニルケトン尿症の治療用のフェニルアラニンヒドロキシラーゼをコードするポリヌクレオチド
|
|
EP3714048B1
(en)
|
2017-11-22 |
2025-04-09 |
ModernaTX, Inc. |
Polynucleotides encoding ornithine transcarbamylase for the treatment of urea cycle disorders
|
|
US20220265856A1
(en)
*
|
2017-11-22 |
2022-08-25 |
Modernatx, Inc. |
Polynucleotides encoding propionyl-coa carboxylase alpha and beta subunits for the treatment of propionic acidemia
|
|
EP3727428A1
(en)
|
2017-12-20 |
2020-10-28 |
Translate Bio, Inc. |
Improved composition and methods for treatment of ornithine transcarbamylase deficiency
|
|
MA51523A
(fr)
|
2018-01-05 |
2020-11-11 |
Modernatx Inc |
Polynucléotides codant pour des anticorps anti-virus du chikungunya
|
|
WO2019148101A1
(en)
|
2018-01-29 |
2019-08-01 |
Modernatx, Inc. |
Rsv rna vaccines
|
|
MA51230A
(fr)
|
2018-01-29 |
2021-05-05 |
Merck Sharp & Dohme |
Protéines f rsv stabilisées et leurs utilisations
|
|
JP2021512090A
(ja)
*
|
2018-01-30 |
2021-05-13 |
モデルナティーエックス， インコーポレイテッド |
免疫細胞に薬剤を送達するための組成物及び方法
|
|
WO2019188867A1
(ja)
|
2018-03-27 |
2019-10-03 |
日油株式会社 |
細胞内動態を改善した新規カチオン性脂質
|
|
WO2019204451A1
(en)
*
|
2018-04-17 |
2019-10-24 |
Carnegie Mellon University |
Enhanced lipid nanoparticle drug delivery using a negatively charged polymer
|
|
US20210220449A1
(en)
|
2018-05-15 |
2021-07-22 |
Translate Bio, Inc. |
Subcutaneous Delivery of Messenger RNA
|
|
WO2019226650A1
(en)
*
|
2018-05-23 |
2019-11-28 |
Modernatx, Inc. |
Delivery of dna
|
|
CN112437767B
(zh)
|
2018-05-24 |
2023-10-27 |
川斯勒佰尔公司 |
硫酯阳离子脂质
|
|
CA3101484A1
(en)
|
2018-05-30 |
2019-12-05 |
Translate Bio, Inc. |
Phosphoester cationic lipids
|
|
CA3101454A1
(en)
|
2018-05-30 |
2019-12-05 |
Translate Bio, Inc. |
Messenger rna vaccines and uses thereof
|
|
JP7463006B2
(ja)
|
2018-05-30 |
2024-04-08 |
トランスレイト バイオ， インコーポレイテッド |
ステロイド性部分を含むカチオン性脂質
|
|
WO2019232095A1
(en)
|
2018-05-30 |
2019-12-05 |
Translate Bio, Inc. |
Vitamin cationic lipids
|
|
CA3100276A1
(en)
|
2018-06-06 |
2019-12-12 |
Massachusetts Institute Of Technology |
Circular rna for translation in eukaryotic cells
|
|
KR20210056331A
(ko)
|
2018-07-23 |
2021-05-18 |
트랜슬레이트 바이오 인코포레이티드 |
전령 rna의 건조 분말 제형
|
|
KR20210091120A
(ko)
|
2018-08-29 |
2021-07-21 |
트랜슬레이트 바이오 인코포레이티드 |
Mrna-로딩된 지질 나노입자를 제조하는 개선된 공정
|
|
WO2020047201A1
(en)
*
|
2018-09-02 |
2020-03-05 |
Modernatx, Inc. |
Polynucleotides encoding very long-chain acyl-coa dehydrogenase for the treatment of very long-chain acyl-coa dehydrogenase deficiency
|
|
EP3849617A1
(en)
|
2018-09-14 |
2021-07-21 |
Translate Bio, Inc. |
Composition and methods for treatment of methylmalonic acidemia
|
|
WO2020056239A1
(en)
*
|
2018-09-14 |
2020-03-19 |
Modernatx, Inc. |
Polynucleotides encoding uridine diphosphate glycosyltransferase 1 family, polypeptide a1 for the treatment of crigler-najjar syndrome
|
|
MA53650A
(fr)
|
2018-09-19 |
2021-07-28 |
Modernatx Inc |
Lipides peg et leurs utilisations
|
|
US12263248B2
(en)
*
|
2018-09-19 |
2025-04-01 |
Modernatx, Inc. |
Compounds and compositions for intracellular delivery of therapeutic agents
|
|
AU2019345067A1
(en)
|
2018-09-19 |
2021-04-08 |
Modernatx, Inc. |
High-purity peg lipids and uses thereof
|
|
CN113271926A
(zh)
*
|
2018-09-20 |
2021-08-17 |
摩登纳特斯有限公司 |
脂质纳米颗粒的制备及其施用方法
|
|
IL281615B2
(en)
|
2018-09-21 |
2026-01-01 |
Acuitas Therapeutics Inc |
Systems and methods for producing lipid nanoparticles and liposomes
|
|
ES3046484T3
(en)
*
|
2018-10-01 |
2025-12-02 |
Alnylam Pharmaceuticals Inc |
Biodegradable lipids for the delivery of active agents
|
|
WO2020072605A1
(en)
|
2018-10-02 |
2020-04-09 |
Intellia Therapeutics, Inc. |
Ionizable amine lipids
|
|
CN113166783B
(zh)
|
2018-10-09 |
2024-10-11 |
不列颠哥伦比亚大学 |
包含无有机溶剂和去污剂的转染活性囊泡的组合物和系统以及与之相关的方法
|
|
JP7543259B2
(ja)
|
2018-10-18 |
2024-09-02 |
アクイタス セラピューティクス インコーポレイテッド |
活性剤の脂質ナノ粒子送達のための脂質
|
|
CA3112837A1
(en)
|
2018-10-19 |
2020-04-23 |
Translate Bio, Inc. |
Pumpless encapsulation of messenger rna
|
|
EP3877444A1
(en)
|
2018-11-09 |
2021-09-15 |
Translate Bio, Inc. |
Multi-peg lipid compounds
|
|
WO2020097379A2
(en)
|
2018-11-09 |
2020-05-14 |
Translate Bio, Inc. |
Peg lipidoid compounds
|
|
WO2020097511A2
(en)
|
2018-11-09 |
2020-05-14 |
Translate Bio, Inc. |
Messenger rna therapy for treatment of ocular diseases
|
|
MX2021005482A
(es)
|
2018-11-09 |
2021-09-08 |
Translate Bio Inc |
Lípidos de 2,5-dioxopiperazina con porciones éster, tioéster, disulfuro y anhidrido intercaladas.
|
|
AU2019378763B2
(en)
|
2018-11-12 |
2025-06-26 |
Translate Bio, Inc. |
Methods for inducing immune tolerance
|
|
CN109320479B
(zh)
*
|
2018-11-13 |
2021-03-16 |
上海克琴科技有限公司 |
一种抗坏血酸四异棕榈酸酯的简便合成方法
|
|
WO2020106903A1
(en)
|
2018-11-21 |
2020-05-28 |
Translate Bio, Inc. |
Cationic lipid compounds and compositions thereof for use in the delivery of messenger rna
|
|
IL314386A
(en)
|
2018-12-05 |
2024-09-01 |
Intellia Therapeutics Inc |
amine modified lipids
|
|
JP2022516356A
(ja)
|
2019-01-07 |
2022-02-25 |
トランスレイト バイオ， インコーポレイテッド |
原発性線毛機能不全症の治療のための組成物および方法
|
|
MY202837A
(en)
|
2019-01-11 |
2024-05-24 |
Acuitas Therapeutics Inc |
Lipids for lipid nanoparticle delivery of active agents
|
|
MX2021009236A
(es)
|
2019-01-31 |
2021-11-12 |
Modernatx Inc |
Agitadores vorticiales y metodos, sistemas y aparatos asociados de estos.
|
|
JP7635131B2
(ja)
|
2019-01-31 |
2025-02-25 |
モデルナティエックス インコーポレイテッド |
脂質ナノ粒子の調製方法
|
|
US11351242B1
(en)
|
2019-02-12 |
2022-06-07 |
Modernatx, Inc. |
HMPV/hPIV3 mRNA vaccine composition
|
|
CN113795579A
(zh)
|
2019-02-20 |
2021-12-14 |
摩登纳特斯有限公司 |
用于共转录加帽的rna聚合酶变体
|
|
US11851694B1
(en)
|
2019-02-20 |
2023-12-26 |
Modernatx, Inc. |
High fidelity in vitro transcription
|
|
CA3128615A1
(en)
*
|
2019-03-01 |
2020-09-10 |
Flagship Pioneering Innovations Vi, Llc |
Topical delivery of polyribonucleic acids
|
|
CA3132975A1
(en)
|
2019-03-11 |
2020-09-17 |
Modernatx, Inc. |
Fed-batch in vitro transcription process
|
|
EP3938379A4
(en)
|
2019-03-15 |
2023-02-22 |
ModernaTX, Inc. |
Hiv rna vaccines
|
|
WO2020214946A1
(en)
|
2019-04-18 |
2020-10-22 |
Translate Bio, Inc. |
Cystine cationic lipids
|
|
WO2020219427A1
(en)
|
2019-04-22 |
2020-10-29 |
Translate Bio, Inc. |
Thioester cationic lipids
|
|
WO2020219876A1
(en)
|
2019-04-25 |
2020-10-29 |
Intellia Therapeutics, Inc. |
Ionizable amine lipids and lipid nanoparticles
|
|
WO2020227085A1
(en)
|
2019-05-03 |
2020-11-12 |
Translate Bio, Inc. |
Di-thioester cationic lipids
|
|
CN114173826A
(zh)
|
2019-05-08 |
2022-03-11 |
阿斯利康(瑞典)有限公司 |
使用脂质纳米颗粒用于递送编码vegf-a多肽的经修饰的rna的方法和包含其的药物组合物
|
|
WO2020237227A1
(en)
|
2019-05-22 |
2020-11-26 |
Massachusetts Institute Of Technology |
Circular rna compositions and methods
|
|
US20220226244A1
(en)
|
2019-05-31 |
2022-07-21 |
Translate Bio, Inc. |
Macrocyclic lipids
|
|
WO2020257611A1
(en)
|
2019-06-21 |
2020-12-24 |
Translate Bio, Inc. |
Cationic lipids comprising an hydroxy moiety
|
|
EP3986858A1
(en)
|
2019-06-21 |
2022-04-27 |
Translate Bio, Inc. |
Tricine and citric acid lipids
|
|
US20230181483A1
(en)
|
2019-07-08 |
2023-06-15 |
Translate Bio, Inc. |
Improved mrna-loaded lipid nanoparticles and processes of making the same
|
|
EP4003311A1
(en)
|
2019-07-23 |
2022-06-01 |
Translate Bio, Inc. |
Stable compositions of mrna-loaded lipid nanoparticles and processes of making
|
|
US12569438B2
(en)
|
2019-07-29 |
2026-03-10 |
Georgia Tech Research Corporation |
Nanomaterials containing constrained lipids and uses thereof
|
|
CA3150061A1
(en)
*
|
2019-08-07 |
2021-02-11 |
Modernatx, Inc. |
Compositions and methods for enhanced delivery of agents
|
|
US12533318B2
(en)
|
2019-08-30 |
2026-01-27 |
Glaxosmithkline Biologicals Sa |
Jet mixing lipid nanoparticle manufacturing process
|
|
AU2020350759A1
(en)
|
2019-09-19 |
2022-03-31 |
Modernatx, Inc. |
Branched tail lipid compounds and compositions for intracellular delivery of therapeutic agents
|
|
BR112022004936A2
(pt)
*
|
2019-09-19 |
2022-06-14 |
Modernatx Inc |
Compostos lipídicos contendo carbonato e composições para distribuição intracelular de agentes terapêuticos
|
|
WO2021055849A1
(en)
*
|
2019-09-19 |
2021-03-25 |
Modernatx, Inc. |
Headgroup lipid compounds and compositions for intracellular delivery of therapeutic agents
|
|
EP4031662A1
(en)
|
2019-09-20 |
2022-07-27 |
Translate Bio, Inc. |
Mrna encoding engineered cftr
|
|
EP4048316A1
(en)
|
2019-10-21 |
2022-08-31 |
Translate Bio, Inc. |
Compositions, methods and uses of messenger rna
|
|
US12378560B2
(en)
|
2019-10-29 |
2025-08-05 |
Northwestern University |
Sequence multiplicity within spherical nucleic acids
|
|
US20240122854A1
(en)
*
|
2019-11-27 |
2024-04-18 |
Acuitas Therapeutics, Inc. |
Novel carbonyl lipids and lipid nanoparticle formulations for delivery of nucleic acids
|
|
AU2020397956A1
(en)
|
2019-12-04 |
2022-07-07 |
Orna Therapeutics, Inc. |
Circular RNA compositions and methods
|
|
US20230051811A1
(en)
|
2019-12-20 |
2023-02-16 |
Translate Bio, Inc |
Rectal delivery of messenger rna
|
|
US12053551B2
(en)
|
2019-12-20 |
2024-08-06 |
Translate Bio, Inc. |
Process of preparing mRNA-loaded lipid nanoparticles
|
|
US12435035B2
(en)
|
2020-01-09 |
2025-10-07 |
Guide Therapeutics, Llc |
Nanomaterials
|
|
WO2021142245A1
(en)
|
2020-01-10 |
2021-07-15 |
Translate Bio, Inc. |
Compounds, pharmaceutical compositions and methods for modulating expression of muc5b in lung cells and tissues
|
|
US20230285297A1
(en)
|
2020-01-31 |
2023-09-14 |
Modernatx, Inc. |
Methods of preparing lipid nanoparticles
|
|
US12194089B2
(en)
|
2020-02-04 |
2025-01-14 |
CureVac SE |
Coronavirus vaccine
|
|
US11241493B2
(en)
|
2020-02-04 |
2022-02-08 |
Curevac Ag |
Coronavirus vaccine
|
|
JP7438604B2
(ja)
*
|
2020-02-07 |
2024-02-27 |
モデルナティエックス インコーポレイテッド |
ＳＡＲＳ－ＣＯＶ－２ ｍＲＮＡドメインワクチン
|
|
WO2021168284A1
(en)
*
|
2020-02-21 |
2021-08-26 |
GIE Medical, Inc. |
Polymer-encapsulated drug particles
|
|
JP7744354B2
(ja)
|
2020-02-25 |
2025-09-25 |
トランスレイト バイオ， インコーポレイテッド |
Ｍｒｎａ担持脂質ナノ粒子を調製する改善された方法
|
|
CA3172423A1
(en)
|
2020-03-20 |
2021-03-22 |
Alex WESSELHOEFT |
Circular rna compositions and methods
|
|
AU2021244559A1
(en)
|
2020-03-24 |
2022-11-17 |
Generation Bio Co. |
Non-viral DNA vectors and uses thereof for expressing Gaucher therapeutics
|
|
MX2022011805A
(es)
|
2020-03-24 |
2023-01-11 |
Generation Bio Co |
Vectores de adn no virales y usos de estos para expresar agentes terapéuticos con factor ix.
|
|
CN111349014A
(zh)
*
|
2020-03-30 |
2020-06-30 |
绵阳达高特新材料有限公司 |
一种方酸甲胺甲酯的制备方法
|
|
EP4132576A1
(en)
|
2020-04-09 |
2023-02-15 |
Suzhou Abogen Biosciences Co., Ltd. |
Nucleic acid vaccines for coronavirus
|
|
US12194157B2
(en)
|
2020-04-09 |
2025-01-14 |
Finncure Oy |
Carrier for targeted delivery to a host
|
|
JP7681617B2
(ja)
*
|
2020-04-09 |
2025-05-22 |
スージョウ・アボジェン・バイオサイエンシズ・カンパニー・リミテッド |
脂質ナノ粒子組成物
|
|
EP4132478A1
(en)
|
2020-04-09 |
2023-02-15 |
Finncure Oy |
Mimetic nanoparticles for preventing the spreading and lowering the infection rate of novel coronaviruses
|
|
EP3901261A1
(en)
|
2020-04-22 |
2021-10-27 |
BioNTech RNA Pharmaceuticals GmbH |
Coronavirus vaccine
|
|
WO2021226463A1
(en)
|
2020-05-07 |
2021-11-11 |
Translate Bio, Inc. |
Composition and methods for treatment of primary ciliary dyskinesia
|
|
US12605399B2
(en)
|
2020-05-07 |
2026-04-21 |
Translate Bio, Inc. |
Compositions for CFTR MRNA therapy
|
|
CA3177940A1
(en)
|
2020-05-07 |
2021-11-11 |
Anusha DIAS |
Optimized nucleotide sequences encoding sars-cov-2 antigens
|
|
AU2021269137A1
(en)
*
|
2020-05-08 |
2022-12-15 |
Orna Therapeutics, Inc. |
Circular RNA compositions and methods
|
|
WO2021231697A1
(en)
|
2020-05-14 |
2021-11-18 |
Translate Bio, Inc. |
Peg lipidoid compounds
|
|
WO2021231901A1
(en)
|
2020-05-15 |
2021-11-18 |
Translate Bio, Inc. |
Lipid nanoparticle formulations for mrna delivery
|
|
US20240042015A1
(en)
|
2020-05-19 |
2024-02-08 |
Orna Therapeutics, Inc. |
Circular rna compositions and methods
|
|
IL298363A
(en)
|
2020-05-20 |
2023-01-01 |
Flagship Pioneering Innovations Vi Llc |
Immunogenic compositions and uses thereof
|
|
CA3179420A1
(en)
|
2020-05-20 |
2021-11-25 |
Avak Kahvejian |
Coronavirus antigen compositions and their uses
|
|
CA3180101A1
(en)
|
2020-05-29 |
2021-12-02 |
Flagship Pioneering Innovations Vi, Llc |
Trem compositions and methods relating thereto
|
|
CA3182026A1
(en)
|
2020-05-29 |
2021-12-02 |
Flagship Pioneering Innovations Vi, Llc. |
Trem compositions and methods relating thereto
|
|
JP2023532707A
(ja)
*
|
2020-06-30 |
2023-07-31 |
スージョウ・アボジェン・バイオサイエンシズ・カンパニー・リミテッド |
脂質化合物及び脂質ナノ粒子組成物
|
|
WO2022006527A1
(en)
|
2020-07-02 |
2022-01-06 |
Maritime Therapeutics, Inc. |
Compositions and methods for reverse gene therapy
|
|
WO2022016070A1
(en)
|
2020-07-16 |
2022-01-20 |
Acuitas Therapeutics, Inc. |
Cationic lipids for use in lipid nanoparticles
|
|
MX2023000806A
(es)
*
|
2020-07-17 |
2023-04-11 |
Generation Bio Co |
Métodos para encapsular polinucleótidos en tamaños reducidos de nanopartículas lipídicas y formulación novedosa de estos.
|
|
CN116234917A
(zh)
|
2020-07-27 |
2023-06-06 |
安杰瑞姆生物科学公司 |
Dna分子组合物及其制备方法和使用方法
|
|
KR20230167008A
(ko)
|
2020-08-06 |
2023-12-07 |
모더나티엑스, 인크. |
지질 나노입자의 제조 방법
|
|
EP4199913A4
(en)
*
|
2020-08-18 |
2024-10-30 |
Ohio State Innovation Foundation |
BIO-INSPIRED LIPID DERIVATIVES AND THEIR USES
|
|
US11406703B2
(en)
|
2020-08-25 |
2022-08-09 |
Modernatx, Inc. |
Human cytomegalovirus vaccine
|
|
US12419948B2
(en)
|
2020-08-31 |
2025-09-23 |
The Broad Institute, Inc. |
Immunogenic compositions and use thereof
|
|
MX2023002439A
(es)
|
2020-09-03 |
2023-05-09 |
Flagship Pioneering Innovations Vi Llc |
Composiciones immunogénicas y usos de las mismas.
|
|
JP2023549011A
(ja)
|
2020-09-15 |
2023-11-22 |
ヴァーヴ・セラピューティクス，インコーポレーテッド |
遺伝子編集のための脂質製剤
|
|
CN116546976A
(zh)
|
2020-10-06 |
2023-08-04 |
翻译生物公司 |
脂质纳米颗粒的改进工艺和配制
|
|
KR20230087536A
(ko)
|
2020-10-12 |
2023-06-16 |
트랜슬레이트 바이오 인코포레이티드 |
Mrna-로딩된 지질 나노입자를 제조하는 개선된 프로세스
|
|
US20220133631A1
(en)
|
2020-10-12 |
2022-05-05 |
Translate Bio, Inc. |
Process of preparing ice-based lipid nanoparticles
|
|
WO2022081707A1
(en)
|
2020-10-13 |
2022-04-21 |
The Government Of The United States, As Represented By The Secretary Of The Army |
Sars-cov-2 dna vaccine and method of administering thereof
|
|
JP2023546175A
(ja)
|
2020-10-14 |
2023-11-01 |
ジョージ・メイソン・リサーチ・ファウンデーション・インコーポレイテッド |
脂質ナノ粒子製造の方法及びそれに由来する組成物
|
|
JP2023548587A
(ja)
|
2020-11-09 |
2023-11-17 |
トランスレイト バイオ， インコーポレイテッド |
コドン最適化したｍＲＮＡの送達のための改善された組成物
|
|
JP2023550644A
(ja)
|
2020-11-25 |
2023-12-04 |
トランスレイト バイオ， インコーポレイテッド |
安定な液状脂質ナノ粒子製剤
|
|
WO2022112855A1
(en)
|
2020-11-27 |
2022-06-02 |
Guangzhou Ribobio Co., Ltd |
Lipid compound and the composition thereof
|
|
CN113185421B
(zh)
*
|
2020-11-27 |
2022-01-25 |
广州市锐博生物科技有限公司 |
脂质化合物及其组合物
|
|
AU2021245162B2
(en)
*
|
2020-11-27 |
2023-12-07 |
Guangzhou Ribobio Co., Ltd |
Lipid compound and the composition thereof
|
|
EP4025556A4
(en)
*
|
2020-11-27 |
2023-08-09 |
Guangzhou Ribobio Co., Ltd |
LIPID COMPOUND AND ITS COMPOSITION
|
|
WO2022110099A1
(en)
|
2020-11-30 |
2022-06-02 |
Guangzhou Argorna Biopharmaceuticals Co., Ltd. |
Coronavirus vaccines and uses thereof
|
|
MX2023007137A
(es)
|
2020-12-21 |
2023-08-28 |
Beam Therapeutics Inc |
Nanomateriales que comprenden acetales unidos a ésteres.
|
|
US20240156946A1
(en)
|
2020-12-22 |
2024-05-16 |
CureVac SE |
Rna vaccine against sars-cov-2 variants
|
|
IL303886A
(en)
|
2020-12-23 |
2023-08-01 |
Flagship Pioneering Inc |
Compositions of modified trems and uses thereof
|
|
US12329811B2
(en)
|
2021-01-11 |
2025-06-17 |
Modernatx, Inc. |
Seasonal RNA influenza virus vaccines
|
|
CA3200333A1
(en)
*
|
2021-01-14 |
2022-07-21 |
Bo YING |
Lipid compounds and lipid nanoparticle compositions
|
|
JP2024504614A
(ja)
|
2021-01-14 |
2024-02-01 |
トランスレイト バイオ， インコーポレイテッド |
ｍＲＮＡがコードする抗体を送達する方法および組成物
|
|
KR20230131863A
(ko)
|
2021-01-20 |
2023-09-14 |
빔 테라퓨틱스, 인크. |
나노물질
|
|
IL303845A
(en)
|
2021-01-20 |
2023-08-01 |
Beam Therapeutics Inc |
Nanomaterials include a degradable property
|
|
US20250325469A1
(en)
|
2021-01-24 |
2025-10-23 |
Michael David FORREST |
Inhibitors of atp synthase - cosmetic and therapeutic uses
|
|
IL305021A
(en)
|
2021-02-08 |
2023-10-01 |
Univ Texas |
Unsaturated Dendrimer Compositions, Related Formulations, and Methods of Using Them
|
|
CN115427432A
(zh)
*
|
2021-02-10 |
2022-12-02 |
斯微(上海)生物科技股份有限公司 |
一种治疗或者预防冠状病毒病突变株的疫苗试剂
|
|
JP2024506908A
(ja)
|
2021-02-12 |
2024-02-15 |
モデルナティエックス インコーポレイテッド |
インビボ療法のためのペイロードを含むｌｎｐ組成物
|
|
US11524023B2
(en)
|
2021-02-19 |
2022-12-13 |
Modernatx, Inc. |
Lipid nanoparticle compositions and methods of formulating the same
|
|
JP2024511437A
(ja)
|
2021-03-23 |
2024-03-13 |
リコード セラピューティクス，インク． |
ポリヌクレオチド組成物、関連製剤、およびその使用方法
|
|
EP4313115A1
(en)
|
2021-03-25 |
2024-02-07 |
Translate Bio, Inc. |
Optimized nucleotide sequences encoding the extracellular domain of human ace2 protein or a portion thereof
|
|
JP2024512669A
(ja)
|
2021-03-31 |
2024-03-19 |
フラグシップ パイオニアリング イノベーションズ ブイ，インコーポレーテッド |
タノトランスミッションポリペプチド及び癌の処置におけるそれらの使用
|
|
BR112023021477A2
(pt)
|
2021-04-17 |
2024-01-30 |
Intellia Therapeutics Inc |
Composições de nanopartículas lipídicas
|
|
CR20230535A
(es)
|
2021-04-17 |
2024-02-16 |
Intellia Therapeutics Inc |
Inhibidores de proteína cinasa dependiente de adn y composiciones y usos de estos
|
|
US20240200106A1
(en)
|
2021-04-17 |
2024-06-20 |
Intellia Thrapeutics, Inc. |
Lipid nanoparticles compositions
|
|
US20250073351A1
(en)
|
2021-04-19 |
2025-03-06 |
Translate Bio, Inc. |
Improved compositions for delivery of mrna
|
|
AU2022260111A1
(en)
|
2021-04-20 |
2023-11-30 |
Anjarium Biosciences Ag |
Compositions of dna molecules encoding amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase, methods of making thereof, and methods of use thereof
|
|
AU2022262794A1
(en)
|
2021-04-23 |
2023-11-02 |
Beth Israel Deaconess Medical Center, Inc. |
Glycan modified nucleic acids, methods of preparation, and therapeutic uses
|
|
CN117881786A
(zh)
|
2021-04-27 |
2024-04-12 |
世代生物公司 |
表达治疗性抗体的非病毒dna载体及其用途
|
|
EP4329884A1
(en)
|
2021-04-27 |
2024-03-06 |
Generation Bio Co. |
Non-viral dna vectors expressing anti-coronavirus antibodies and uses thereof
|
|
EP4182295A1
(en)
*
|
2021-05-06 |
2023-05-24 |
Stemirna Therapeutics Co., Ltd. |
A lipid
|
|
WO2022234003A1
(en)
|
2021-05-07 |
2022-11-10 |
Avacta Life Sciences Limited |
Cd33 binding polypeptides with stefin a protein
|
|
WO2022236093A1
(en)
*
|
2021-05-07 |
2022-11-10 |
Carnegie Mellon University |
LIPID NANOPARTICLE-MEDIATED mRNA DELIVERY TO THE PANCREAS
|
|
US20220363937A1
(en)
|
2021-05-14 |
2022-11-17 |
Armstrong World Industries, Inc. |
Stabilization of antimicrobial coatings
|
|
CA3211623A1
(en)
|
2021-05-24 |
2022-12-01 |
Bo YING |
Lipid compounds and lipid nanoparticle compositions
|
|
TW202317767A
(zh)
|
2021-06-10 |
2023-05-01 |
美商歐納醫療公司 |
環狀rna組合物及方法
|
|
CN113387825A
(zh)
*
|
2021-06-10 |
2021-09-14 |
福州大学 |
长链烷基酯胺类化合物或含氟长链烷基酯胺类化合物及其公斤级制备方法
|
|
WO2022266032A1
(en)
|
2021-06-14 |
2022-12-22 |
Generation Bio Co. |
Cationic lipids and compositions thereof
|
|
JP2024527541A
(ja)
|
2021-07-01 |
2024-07-25 |
トランスレイト バイオ， インコーポレイテッド |
Ｍｒｎａの送達のための組成物
|
|
CN114149337B
(zh)
*
|
2021-07-07 |
2022-04-29 |
天津键凯科技有限公司 |
一种用于核酸递送的新型可电离脂质及其lnp组合物
|
|
CN115611757A
(zh)
*
|
2021-07-16 |
2023-01-17 |
江苏慧聚药业股份有限公司 |
mRNA传递剂的合成
|
|
US12251471B2
(en)
*
|
2021-07-26 |
2025-03-18 |
Oregon State University |
Inhalable therapeutics
|
|
WO2023009547A1
(en)
|
2021-07-26 |
2023-02-02 |
Flagship Pioneering Innovations Vi, Llc |
Trem compositions and uses thereof
|
|
US20240335393A1
(en)
*
|
2021-07-26 |
2024-10-10 |
Modernatx, Inc. |
Processes for preparing lipid nanoparticle compositions
|
|
WO2023018831A2
(en)
*
|
2021-08-11 |
2023-02-16 |
RNAimmune, Inc. |
Composition and methods of mrna vaccines against novel coronavirus infection
|
|
CN115703714B
(zh)
*
|
2021-08-13 |
2025-06-10 |
广州谷森制药有限公司 |
阳离子脂质化合物
|
|
CN115703713B
(zh)
*
|
2021-08-13 |
2025-06-10 |
广州谷森制药有限公司 |
阳离子脂质化合物
|
|
WO2023023055A1
(en)
|
2021-08-16 |
2023-02-23 |
Renagade Therapeutics Management Inc. |
Compositions and methods for optimizing tropism of delivery systems for rna
|
|
MX2024002726A
(es)
|
2021-09-03 |
2024-03-20 |
CureVac SE |
Nuevas nanoparticulas lipidicas para la administracion de acidos nucleicos.
|
|
TW202328067A
(zh)
|
2021-09-14 |
2023-07-16 |
美商雷納嘉德醫療管理公司 |
環狀脂質及其使用方法
|
|
CN118317944A
(zh)
|
2021-09-14 |
2024-07-09 |
雷纳嘉德医疗管理公司 |
非环状脂质及其使用方法
|
|
ES2994006T3
(en)
|
2021-09-17 |
2025-01-16 |
Flagship Pioneering Innovations Vi Llc |
Compositions and methods for producing circular polyribonucleotides
|
|
EP4408825A1
(en)
|
2021-09-30 |
2024-08-07 |
Orna Therapeutics, Inc. |
Lipid nanoparticle compositions for delivering circular polynucleotides
|
|
US20250017867A1
(en)
*
|
2021-10-01 |
2025-01-16 |
Modernatx, Inc. |
Polynucleotides encoding relaxin for the treatment of fibrosis and/or cardiovascular disease
|
|
TW202334196A
(zh)
|
2021-10-07 |
2023-09-01 |
英商阿法克塔生命科學有限公司 |
Pd-l1結合多肽
|
|
TW202332694A
(zh)
|
2021-10-07 |
2023-08-16 |
英商阿凡克塔生命科學公司 |
血清半衰期延長之ｐｄ－ｌ１結合多肽
|
|
AR127312A1
(es)
|
2021-10-08 |
2024-01-10 |
Suzhou Abogen Biosciences Co Ltd |
Compuestos lipídicos ycomposiciones de nanopartículas lipídicas
|
|
CA3234127A1
(en)
*
|
2021-10-08 |
2023-04-13 |
Suzhou Abogen Biosciences Co., Ltd. |
Lipid compounds and lipid nanoparticle compositions
|
|
WO2023064469A1
(en)
|
2021-10-13 |
2023-04-20 |
Modernatx, Inc. |
Compositions of mrna-encoded il15 fusion proteins and methods of use thereof
|
|
JP2024538144A
(ja)
|
2021-10-18 |
2024-10-18 |
フラッグシップ パイオニアリング イノベーションズ シックス，エルエルシー |
ポリリボヌクレオチドを精製するための組成物及び方法
|
|
KR20240090727A
(ko)
|
2021-10-22 |
2024-06-21 |
세일 바이오메디슨스, 인크. |
Mrna 백신 조성물
|
|
WO2023073228A1
(en)
|
2021-10-29 |
2023-05-04 |
CureVac SE |
Improved circular rna for expressing therapeutic proteins
|
|
WO2023076733A1
(en)
|
2021-11-01 |
2023-05-04 |
Dana-Farber Cancer Institute, Inc. |
Biologically selected nucleic acid artificial mini-proteome libraries
|
|
EP4426832A1
(en)
|
2021-11-03 |
2024-09-11 |
The J. David Gladstone Institutes, A Testamentary Trust Established under The Will of J. David Gladstone |
Precise genome editing using retrons
|
|
EP4430024A1
(en)
|
2021-11-08 |
2024-09-18 |
Orna Therapeutics, Inc. |
Lipid nanoparticle compositions for delivering circular polynucleotides
|
|
JP2024545572A
(ja)
|
2021-11-10 |
2024-12-10 |
トランスレイト バイオ， インコーポレイテッド |
原発性線毛機能不全の治療のための組成物及び方法
|
|
CN118488834A
(zh)
|
2021-11-23 |
2024-08-13 |
赛欧生物医药股份有限公司 |
细菌源性脂质组合物和其用途
|
|
AU2022397292A1
(en)
|
2021-11-24 |
2024-05-30 |
Flagship Pioneering Innovations Vi, Llc |
Varicella-zoster virus immunogen compositions and their uses
|
|
EP4436984A1
(en)
|
2021-11-24 |
2024-10-02 |
Flagship Pioneering Innovations VI, LLC |
Coronavirus immunogen compositions and their uses
|
|
MX2024006440A
(es)
|
2021-11-24 |
2024-08-19 |
Flagship Pioneering Innovations Vi Llc |
Composiciones inmunogenicas y sus usos.
|
|
US12186387B2
(en)
|
2021-11-29 |
2025-01-07 |
BioNTech SE |
Coronavirus vaccine
|
|
AR127892A1
(es)
|
2021-12-10 |
2024-03-06 |
Modernatx Inc |
Compuestos y composiciones para la administración de agentes terapéuticos
|
|
CA3242402A1
(en)
|
2021-12-16 |
2023-06-22 |
Acuitas Therapeutics, Inc. |
Lipids for use in lipid nanoparticle formulations
|
|
US20250049728A1
(en)
|
2021-12-16 |
2025-02-13 |
Modernatx, Inc. |
Processes for preparing lipid nanoparticles
|
|
JP2024546855A
(ja)
|
2021-12-17 |
2024-12-26 |
フラッグシップ パイオニアリング イノベーションズ シックス，エルエルシー |
変性条件下での環状ｒｎａの濃縮方法
|
|
EP4452930A1
(en)
|
2021-12-20 |
2024-10-30 |
Beam Therapeutics Inc. |
Ionizable amine and ester lipids and lipid nanoparticles
|
|
EP4452925A1
(en)
|
2021-12-20 |
2024-10-30 |
Beam Therapeutics Inc. |
Nanomaterial comprising diamines
|
|
CA3241488A1
(en)
|
2021-12-20 |
2023-06-29 |
Beam Therapeutics Inc. |
Ionizable amine lipids and lipid nanoparticles
|
|
WO2023122080A1
(en)
|
2021-12-20 |
2023-06-29 |
Senda Biosciences, Inc. |
Compositions comprising mrna and lipid reconstructed plant messenger packs
|
|
EP4452942A1
(en)
|
2021-12-20 |
2024-10-30 |
Beam Therapeutics Inc. |
Nanomaterials comprising disulfides
|
|
WO2023121971A1
(en)
|
2021-12-20 |
2023-06-29 |
Beam Therapeutics Inc. |
Nanomaterials comprising tetravalent lipid compounds
|
|
US12529047B1
(en)
|
2021-12-21 |
2026-01-20 |
Modernatx, Inc. |
mRNA quantification methods
|
|
KR20240117149A
(ko)
|
2021-12-22 |
2024-07-31 |
플래그쉽 파이어니어링 이노베이션스 브이아이, 엘엘씨 |
폴리리보뉴클레오티드를 정제하기 위한 조성물 및 방법
|
|
US20250108007A1
(en)
*
|
2021-12-23 |
2025-04-03 |
Suzhou Abogen Biosciences Co., Ltd. |
Lipid compound and lipid nanoparticle composition
|
|
MX2024007870A
(es)
|
2021-12-23 |
2024-08-15 |
Flagship Pioneering Innovations Vi Llc |
Polirribonucleotidos circulares que codifican polipeptidos antifusogenicos.
|
|
WO2023122752A1
(en)
|
2021-12-23 |
2023-06-29 |
Renagade Therapeutics Management Inc. |
Constrained lipids and methods of use thereof
|
|
CN120476106A
(zh)
|
2021-12-29 |
2025-08-12 |
江苏恒瑞医药股份有限公司 |
用于递送的脂质和组合物
|
|
CN117377651B
(zh)
*
|
2021-12-31 |
2025-04-01 |
厦门赛诺邦格生物科技股份有限公司 |
一种侧链含功能性基团的阳离子脂质及其应用
|
|
CN114957027B
(zh)
*
|
2022-01-13 |
2023-05-19 |
北京悦康科创医药科技股份有限公司 |
一种阳离子脂质化合物、包含其的组合物及用途
|
|
JP2025504404A
(ja)
|
2022-01-14 |
2025-02-12 |
アンジャリウム バイオサイエンシズ エージー |
Ｖｉｉｉ因子をコードするｄｎａ分子の組成物、それを作製する方法、及びその使用方法
|
|
TW202330457A
(zh)
*
|
2022-01-19 |
2023-08-01 |
大陸商蘇州艾博生物科技有限公司 |
脂質化合物和脂質奈米顆粒組合物
|
|
WO2023141586A1
(en)
|
2022-01-21 |
2023-07-27 |
Orna Therapeutics, Inc. |
Systemic administration of circular rna polynucleotides encoding muscle proteins or protein complexes
|
|
WO2023141602A2
(en)
|
2022-01-21 |
2023-07-27 |
Renagade Therapeutics Management Inc. |
Engineered retrons and methods of use
|
|
US20250099614A1
(en)
|
2022-01-28 |
2025-03-27 |
CureVac SE |
Nucleic acid encoded transcription factor inhibitors
|
|
CA3250180A1
(en)
*
|
2022-01-31 |
2023-08-03 |
Genevant Sciences Gmbh |
IONIZABLE CATIONIC LIPIDS FOR LIPID NANOPARTICLES
|
|
WO2023154818A1
(en)
|
2022-02-09 |
2023-08-17 |
Modernatx, Inc. |
Mucosal administration methods and formulations
|
|
CN114456081B
(zh)
*
|
2022-02-15 |
2025-03-11 |
浙江汇科泽华生物技术有限公司 |
一种可离子化脂质及其制备方法和应用
|
|
EP4479097A1
(en)
|
2022-02-15 |
2024-12-25 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and pharmaceutical compositions for modulating tear film composition to treat corneal defects
|
|
WO2023159197A1
(en)
*
|
2022-02-18 |
2023-08-24 |
Modernatx, Inc. |
Mrnas encoding checkpoint cancer vaccines and uses thereof
|
|
EP4482819A2
(en)
*
|
2022-02-24 |
2025-01-01 |
Vivasor, Inc. |
Novel ionizable cationic lipids
|
|
WO2023177655A1
(en)
|
2022-03-14 |
2023-09-21 |
Generation Bio Co. |
Heterologous prime boost vaccine compositions and methods of use
|
|
WO2023179497A1
(zh)
*
|
2022-03-21 |
2023-09-28 |
苏州科锐迈德生物医药科技有限公司 |
一种脂质化合物及基于其的脂质载体、核酸脂质纳米粒组合物和药物制剂
|
|
KR102560772B1
(ko)
*
|
2022-03-21 |
2023-07-28 |
주식회사 메디치바이오 |
신규한 이온화지질 및 이를 이용한 지질나노입자 조성물
|
|
WO2023183082A1
(en)
|
2022-03-24 |
2023-09-28 |
The Regents Of The University Of California |
Silyl lipids suitable for enhanced delivery of anti-viral therapeutics
|
|
EP4499607A1
(en)
|
2022-03-25 |
2025-02-05 |
Sail Biomedicines, Inc. |
Novel ionizable lipids and lipid nanoparticles and methods of using the same
|
|
WO2023193002A1
(en)
|
2022-04-01 |
2023-10-05 |
Modernatx, Inc. |
Cross mixers for lipid nanoparticle production, and methods of operating the same
|
|
WO2023196615A1
(en)
|
2022-04-07 |
2023-10-12 |
RNAimmune, Inc. |
Compounds and compositions for drug delivery
|
|
CA3255619A1
(en)
|
2022-04-07 |
2023-10-12 |
Renagade Therapeutics Management Inc. |
CYCLIC LIPIDS AND LIPID NANOPARTICLES (LPNs) FOR THE SUPPLY OF NUCLEIC ACIDS OR PEPTIDES INTENDED FOR USE IN VACCINATION AGAINST INFECTIOUS AGENTS
|
|
JP2025511756A
(ja)
|
2022-04-08 |
2025-04-16 |
フラッグシップ パイオニアリング イノベーションズ セブン，エルエルシー |
ワクチン及び関連する方法
|
|
WO2023208118A1
(zh)
|
2022-04-27 |
2023-11-02 |
瑞可迪（上海）生物医药有限公司 |
核酸构建体及其应用
|
|
US20250295687A1
(en)
|
2022-05-09 |
2025-09-25 |
Flagship Pioneering Innovations Vi, Llc |
Trem compositions and methods of use for treating proliferative disorders
|
|
WO2023218243A1
(en)
|
2022-05-12 |
2023-11-16 |
Avacta Life Sciences Limited |
Lag-3/pd-l1 binding fusion proteins
|
|
TW202400784A
(zh)
|
2022-05-13 |
2024-01-01 |
大陸商上海瑞宏迪醫藥有限公司 |
包含utr的核酸構建體及其應用
|
|
WO2023218431A1
(en)
|
2022-05-13 |
2023-11-16 |
BioNTech SE |
Rna compositions targeting hiv
|
|
JP2025516638A
(ja)
|
2022-05-13 |
2025-05-30 |
フラッグシップ パイオニアリング イノベーションズ セブン，エルエルシー |
二本鎖ｄｎａ組成物及び関連する方法
|
|
KR20250021330A
(ko)
|
2022-05-25 |
2025-02-12 |
비온테크 에스이 |
원숭이두창 항원 전달을 위한 rna 조성물 및 관련 방법
|
|
WO2023227608A1
(en)
|
2022-05-25 |
2023-11-30 |
Glaxosmithkline Biologicals Sa |
Nucleic acid based vaccine encoding an escherichia coli fimh antigenic polypeptide
|
|
US20250375534A1
(en)
|
2022-05-30 |
2025-12-11 |
BioNTech SE |
Complexes for delivery of nucleic acids
|
|
EP4536197A1
(en)
|
2022-06-07 |
2025-04-16 |
Generation Bio Co. |
Lipid nanoparticle compositions and uses thereof
|
|
CN117304023A
(zh)
*
|
2022-06-16 |
2023-12-29 |
海南普利制药股份有限公司 |
用于mRNA递送的可离子化脂质中间体的制备方法
|
|
CN117285474A
(zh)
*
|
2022-06-16 |
2023-12-26 |
南京诺唯赞生物科技股份有限公司 |
一类新的脂质化合物及其用途
|
|
US20250179492A1
(en)
|
2022-06-22 |
2025-06-05 |
Flagship Pioneering Innovations Vi, Llc |
Compositions of modified trems and uses thereof
|
|
US12297285B2
(en)
|
2022-06-24 |
2025-05-13 |
Orna Therapeutics, Inc. |
Circular RNA encoding chimeric antigen receptors targeting BCMA
|
|
WO2024002985A1
(en)
|
2022-06-26 |
2024-01-04 |
BioNTech SE |
Coronavirus vaccine
|
|
JP2025525569A
(ja)
|
2022-07-18 |
2025-08-05 |
レナゲード セラピューティクス マネージメント インコーポレイテッド |
遺伝子編集成分、システム、及び使用方法
|
|
WO2024019936A1
(en)
|
2022-07-20 |
2024-01-25 |
Beam Therapeutics Inc. |
Nanomaterials comprising triols
|
|
JP2025525778A
(ja)
|
2022-08-01 |
2025-08-07 |
フラッグシップ パイオニアリング イノベーションズ セブン，エルエルシー |
免疫調節タンパク質及び関連方法
|
|
EP4565572A1
(en)
*
|
2022-08-05 |
2025-06-11 |
Life Technologies Corporation |
Lipids for nucleic acid delivery
|
|
US20260102346A1
(en)
*
|
2022-08-09 |
2026-04-16 |
Stemirna Therapeutics Co., Ltd. |
Lipid composition
|
|
WO2024035932A1
(en)
|
2022-08-11 |
2024-02-15 |
RNAimmune, Inc. |
Lyophilized nanoparticle compositions and methods of use thereof
|
|
EP4569112A1
(en)
|
2022-08-12 |
2025-06-18 |
Remix Therapeutics Inc. |
Methods and compositions for modulating splicing at alternative splice sites
|
|
WO2024040222A1
(en)
|
2022-08-19 |
2024-02-22 |
Generation Bio Co. |
Cleavable closed-ended dna (cedna) and methods of use thereof
|
|
WO2024044147A1
(en)
|
2022-08-23 |
2024-02-29 |
Modernatx, Inc. |
Methods for purification of ionizable lipids
|
|
WO2024044723A1
(en)
|
2022-08-25 |
2024-02-29 |
Renagade Therapeutics Management Inc. |
Engineered retrons and methods of use
|
|
AU2023334610A1
(en)
|
2022-08-31 |
2025-03-13 |
Sail Biomedicines, Inc. |
Novel ionizable lipids and lipid nanoparticles and methods of using the same
|
|
CN120152962A
(zh)
|
2022-09-06 |
2025-06-13 |
国立大学法人九州大学 |
脂质纳米粒子
|
|
WO2024054669A2
(en)
*
|
2022-09-08 |
2024-03-14 |
Nanotech Pharma Inc. |
Compounds and compositions for intracellular delivery of nucleic acid-based therapeutics and methods thereof
|
|
CN120554239A
(zh)
*
|
2022-09-09 |
2025-08-29 |
厦门赛诺邦格生物科技股份有限公司 |
一种碳核阳离子脂质
|
|
CN115197431B
(zh)
*
|
2022-09-15 |
2022-11-29 |
清华大学 |
脂质偶联完全可降解水溶性聚合物的合成及应用
|
|
EP4342460A1
(en)
|
2022-09-21 |
2024-03-27 |
NovoArc GmbH |
Lipid nanoparticle with nucleic acid cargo
|
|
WO2024077191A1
(en)
|
2022-10-05 |
2024-04-11 |
Flagship Pioneering Innovations V, Inc. |
Nucleic acid molecules encoding trif and additionalpolypeptides and their use in treating cancer
|
|
GB202215200D0
(en)
|
2022-10-14 |
2022-11-30 |
Mercurna B V |
Novel ionizable lipids
|
|
WO2024089638A1
(en)
|
2022-10-28 |
2024-05-02 |
Glaxosmithkline Biologicals Sa |
Nucleic acid based vaccine
|
|
WO2024089229A1
(en)
|
2022-10-28 |
2024-05-02 |
CureVac SE |
Improved formulations comprising lipid-based carriers encapsulating rna
|
|
AU2023372397A1
(en)
|
2022-10-31 |
2025-05-08 |
Flagship Pioneering Innovations Vi, Llc |
Compositions and methods for purifying polyribonucleotides
|
|
US12280104B2
(en)
|
2022-11-01 |
2025-04-22 |
RNAimmune, Inc. |
Composition and methods for MRNA vaccines against novel omicron coronavirus infections
|
|
CN120390656A
(zh)
|
2022-11-08 |
2025-07-29 |
欧纳医疗公司 |
环状rna组合物
|
|
TW202425959A
(zh)
|
2022-11-08 |
2024-07-01 |
美商歐納醫療公司 |
遞送多核苷酸的脂質及奈米顆粒組合物
|
|
EP4615465A1
(en)
|
2022-11-08 |
2025-09-17 |
Flagship Pioneering Innovations VI, LLC |
Compositions and methods for producing circular polyribonucleotides
|
|
WO2024102762A1
(en)
|
2022-11-08 |
2024-05-16 |
Orna Therapeutics, Inc. |
Lipids and lipid nanoparticle compositions for delivering polynucleotides
|
|
EP4615424A1
(en)
|
2022-11-10 |
2025-09-17 |
Sail Biomedicines, Inc. |
Rna compositions comprising lipid nanoparticles or lipid reconstructed natural messenger packs
|
|
WO2024107702A1
(en)
*
|
2022-11-14 |
2024-05-23 |
Board Of Regents, The University Of Texas System |
Aerosolized lipid nanoparticles and uses thereof
|
|
EP4622630A1
(en)
|
2022-11-21 |
2025-10-01 |
Translate Bio, Inc. |
Compositions of dry powder formulations of messenger rna and methods of use thereof
|
|
JP2025540076A
(ja)
|
2022-12-01 |
2025-12-11 |
ジェネレーション バイオ カンパニー |
核酸、イオン化可能な脂質、ステロール、脂質アンカーポリマー、及びヘルパー脂質を含む脂質ナノ粒子、それらの使用
|
|
WO2024119103A1
(en)
|
2022-12-01 |
2024-06-06 |
Generation Bio Co. |
Lipid nanoparticles comprising nucleic acids and lipid-anchored polymers
|
|
KR20250131271A
(ko)
|
2022-12-01 |
2025-09-02 |
제너레이션 바이오 컴퍼니 |
신규한 폴리글리세롤-접합된 지질 및 이를 포함하는 지질 나노입자 조성물
|
|
KR20250114116A
(ko)
|
2022-12-01 |
2025-07-28 |
제너레이션 바이오 컴퍼니 |
세포 표적화를 위한 스텔스 지질 나노입자 조성물
|
|
EP4626858A1
(en)
*
|
2022-12-02 |
2025-10-08 |
University of Cincinnati |
Novel ionizable lipids and lipid nanoparticles comprising the same
|
|
WO2024119098A1
(en)
*
|
2022-12-02 |
2024-06-06 |
Prime Medicine, Inc. |
Lipid nanoparticle (lnp) delivery systems and formulations
|
|
EP4630057A1
(en)
|
2022-12-08 |
2025-10-15 |
Recode Therapeutics, Inc. |
Lipid nanoparticle compositions and uses thereof
|
|
WO2024123978A1
(en)
|
2022-12-08 |
2024-06-13 |
Modernatx, Inc. |
Ionizable lipids with malonate tails
|
|
TW202430215A
(zh)
|
2022-12-14 |
2024-08-01 |
美商旗艦先鋒創新有限責任（Ｖｉｉ）公司 |
用於將治療劑遞送至骨之組成物和方法
|
|
EP4633673A1
(en)
|
2022-12-15 |
2025-10-22 |
Sanofi Pasteur Inc. |
Mrna encoding influenza virus-like particle
|
|
WO2024133515A1
(en)
|
2022-12-20 |
2024-06-27 |
Sanofi |
Rhinovirus mrna vaccine
|
|
WO2024131810A1
(en)
*
|
2022-12-21 |
2024-06-27 |
Suzhou Abogen Biosciences Co., Ltd. |
Lipid nanoparticles comprising sterol-modified phospholipids
|
|
WO2024138189A2
(en)
|
2022-12-22 |
2024-06-27 |
Intellia Therapeutics, Inc. |
Methods for analyzing nucleic acid cargos of lipid nucleic acid assemblies
|
|
IL321425A
(en)
|
2022-12-23 |
2025-08-01 |
Biontech Delivery Tech Gmbh |
compound
|
|
WO2024141955A1
(en)
|
2022-12-28 |
2024-07-04 |
BioNTech SE |
Rna compositions targeting hiv
|
|
AU2023414262B2
(en)
|
2022-12-29 |
2025-08-14 |
Rinuagene Biotechnology Co., Ltd. |
Polynucleotide molecule for preventing or treating hpv infection-related diseases
|
|
CN120435314A
(zh)
|
2022-12-29 |
2025-08-05 |
波普瓦克斯私人有限公司 |
多靶疫苗和治疗剂
|
|
WO2024141784A2
(en)
|
2022-12-29 |
2024-07-04 |
Popvax Private Limited |
Broadly protective betacoronavirus vaccines and compositions
|
|
EP4642434A2
(en)
*
|
2022-12-29 |
2025-11-05 |
Life Technologies Corporation |
Lipid compositions on the basis of ionizable lipids, use for delivery to immune cells
|
|
CN116178193B
(zh)
|
2023-01-05 |
2023-07-28 |
北京悦康科创医药科技股份有限公司 |
高效低毒且稳定性表达的阳离子脂质化合物及其组合物
|
|
CN116375592B
(zh)
|
2023-01-05 |
2025-05-16 |
北京悦康科创医药科技股份有限公司 |
长效低毒的新型阳离子脂质化合物及其组合物
|
|
CN115677518B
(zh)
|
2023-01-05 |
2023-04-14 |
北京悦康科创医药科技股份有限公司 |
用于递送核酸的可电离阳离子脂质化合物和组合物及用途
|
|
JP2026501733A
(ja)
*
|
2023-01-05 |
2026-01-16 |
セロン ファーマ エス．アー． |
核酸送達用の新規なイオン化可能脂質化合物
|
|
US20240252520A1
(en)
|
2023-01-09 |
2024-08-01 |
Beth Israel Deaconess Medical Center, Inc. |
Therapeutic agents and their use for treating chronic wounds
|
|
WO2024151583A2
(en)
|
2023-01-09 |
2024-07-18 |
Flagship Pioneering Innovations Vii, Llc |
Vaccines and related methods
|
|
US20240238473A1
(en)
|
2023-01-09 |
2024-07-18 |
Beth Israel Deaconess Medical Center, Inc. |
Recombinant nucleic acid molecules and their use in wound healing
|
|
WO2024151687A1
(en)
|
2023-01-09 |
2024-07-18 |
Flagship Pioneering Innovations V, Inc. |
Genetic switches and their use in treating cancer
|
|
CN121057577A
(zh)
|
2023-01-27 |
2025-12-02 |
赛欧生物医药股份有限公司 |
经修饰的脂质组合物及其用途
|
|
EP4658636A1
(en)
*
|
2023-01-31 |
2025-12-10 |
Pfizer Inc. |
Lipid compounds and uses thereof
|
|
WO2024167885A1
(en)
|
2023-02-06 |
2024-08-15 |
Flagship Pioneering Innovations Vii, Llc |
Immunomodulatory compositions and related methods
|
|
CN115784921B
(zh)
|
2023-02-08 |
2023-05-05 |
北京悦康科创医药科技股份有限公司 |
肝外靶向高效低毒的阳离子脂质化合物及其组合物
|
|
IL322468A
(en)
*
|
2023-02-13 |
2025-09-01 |
Flagship Pioneering Innovations Vii Llc |
Ionizable lipids containing degradable crosslinkers and lipid carriers for therapeutic compositions
|
|
IL322378A
(en)
|
2023-02-17 |
2025-09-01 |
Flagship Pioneering Innovations Vii Llc |
DNA compositions containing modified cytosine
|
|
JP2026507513A
(ja)
|
2023-02-17 |
2026-03-04 |
フラッグシップ パイオニアリング イノベーションズ セブン，エルエルシー |
修飾されたウラシルを含むｄｎａ組成物
|
|
WO2024175604A1
(en)
|
2023-02-21 |
2024-08-29 |
Institut National de la Santé et de la Recherche Médicale |
Methods and pharmaceutical composition for the treatment of sanfilippo syndrome type iiib
|
|
WO2024178305A1
(en)
|
2023-02-24 |
2024-08-29 |
Modernatx, Inc. |
Compositions of mrna-encoded il-15 fusion proteins and methods of use thereof for treating cancer
|
|
KR20250153298A
(ko)
|
2023-03-08 |
2025-10-24 |
큐어백 에스이 |
핵산 전달을 위한 신규의 지질 나노입자 제형
|
|
WO2024192420A1
(en)
|
2023-03-15 |
2024-09-19 |
Flagship Pioneering Innovations Vi, Llc |
Compositions comprising polyribonucleotides and uses thereof
|
|
WO2024192291A1
(en)
|
2023-03-15 |
2024-09-19 |
Renagade Therapeutics Management Inc. |
Delivery of gene editing systems and methods of use thereof
|
|
EP4680276A1
(en)
|
2023-03-15 |
2026-01-21 |
Flagship Pioneering Innovations VI, LLC |
Immunogenic compositions and uses thereof
|
|
EP4680595A2
(en)
|
2023-03-15 |
2026-01-21 |
Renagade Therapeutics Management Inc. |
Lipid nanoparticles comprising coding rna molecules for use in gene editing and as vaccines and therapeutic agents
|
|
KR20240159310A
(ko)
*
|
2023-04-28 |
2024-11-05 |
주식회사 메디치바이오 |
신규한 이온화지질을 이용한 지질나노입자 조성물
|
|
WO2024197309A1
(en)
|
2023-03-23 |
2024-09-26 |
Modernatx, Inc. |
Peg targeting compounds for delivery of therapeutics
|
|
WO2024197310A1
(en)
|
2023-03-23 |
2024-09-26 |
Modernatx, Inc. |
Peg targeting compounds for delivery of therapeutics
|
|
EP4683665A1
(en)
|
2023-03-23 |
2026-01-28 |
ModernaTX, Inc. |
Peg targeting compounds for delivery of therapeutics
|
|
WO2024205657A2
(en)
|
2023-03-29 |
2024-10-03 |
Orna Therapeutics, Inc. |
Lipids and lipid nanoparticle compositions for delivering polynucleotides
|
|
CN121358499A
(zh)
|
2023-03-30 |
2026-01-16 |
Ose免疫疗法 |
靶向活化的免疫细胞以表达免疫细胞增强分子的基于脂质的纳米粒及其用途
|
|
AU2024254671A1
(en)
|
2023-03-30 |
2025-10-02 |
Ose Immunotherapeutics |
Method of synthesis of targeted lipid nanoparticle and uses thereof
|
|
WO2024216191A1
(en)
|
2023-04-12 |
2024-10-17 |
Flagship Pioneering Innovations Vi, Llc |
Modified trems, compositions, and related methods thereof
|
|
WO2024216128A1
(en)
|
2023-04-12 |
2024-10-17 |
Flagship Pioneering Innovations Vi, Llc |
Trems for use in correction of missense mutations
|
|
CN120957707A
(zh)
|
2023-04-17 |
2025-11-14 |
赛诺菲巴斯德有限公司 |
可复溶干粉配制品及其使用方法
|
|
WO2024220752A2
(en)
|
2023-04-19 |
2024-10-24 |
Sail Biomedicines, Inc. |
Rna therapeutic compositions
|
|
WO2024220712A2
(en)
|
2023-04-19 |
2024-10-24 |
Sail Biomedicines, Inc. |
Vaccine compositions
|
|
EP4698150A1
(en)
|
2023-04-19 |
2026-02-25 |
Sail Biomedicines, Inc. |
Delivery of polynucleotides from lipid nanoparticles comprising rna and ionizable lipids
|
|
WO2024220746A2
(en)
|
2023-04-21 |
2024-10-24 |
Flagship Pioneering Innovations Vii, Llc |
Rnai agents targeting fatty acid synthase and related methods
|
|
CN117384055B
(zh)
*
|
2023-04-27 |
2024-11-19 |
仁景(苏州)生物科技有限公司 |
用于递送治疗剂的可电离脂质及其用途
|
|
WO2024226958A2
(en)
*
|
2023-04-28 |
2024-10-31 |
Nitto Denko Corporation |
Lipids, pharmaceutical compositions comprising the same and methods of delivering active pharmaceutical ingredients
|
|
WO2024233308A2
(en)
|
2023-05-05 |
2024-11-14 |
Orna Therapeutics, Inc. |
Circular rna compositions and methods
|
|
WO2024230934A1
(en)
|
2023-05-11 |
2024-11-14 |
CureVac SE |
Therapeutic nucleic acid for the treatment of ophthalmic diseases
|
|
EP4713003A1
(en)
|
2023-05-17 |
2026-03-25 |
Institut National de la Santé et de la Recherche Médicale |
Lipc variant in the treatment of hypercholesterolemia and atherosclerotic cardiovascular disease
|
|
TW202502729A
(zh)
|
2023-05-19 |
2025-01-16 |
美商英特利亞醫療公司 |
可電離胺脂質
|
|
US12311033B2
(en)
|
2023-05-31 |
2025-05-27 |
Capstan Therapeutics, Inc. |
Lipid nanoparticle formulations and compositions
|
|
WO2024258829A1
(en)
|
2023-06-12 |
2024-12-19 |
Flagship Pioneering Innovations Vii, Llc |
Sars-cov-2 vaccine compositions and related methods
|
|
EP4727914A1
(en)
|
2023-06-14 |
2026-04-22 |
ModernaTX, Inc. |
Compounds and compositions for delivery of therapeutic agents
|
|
CN121646576A
(zh)
*
|
2023-06-16 |
2026-03-10 |
爱康泰生治疗公司 |
用于脂质纳米颗粒的脂质
|
|
EP4731655A1
(en)
|
2023-06-23 |
2026-04-29 |
CureVac SE |
Nucleic acid encoded antibodies
|
|
WO2025006684A1
(en)
|
2023-06-28 |
2025-01-02 |
Flagship Pioneering Innovations Vi, Llc |
Circular polyribonucleotides encoding antifusogenic polypeptides
|
|
CN121712487A
(zh)
|
2023-06-28 |
2026-03-20 |
赛诺菲巴斯德有限公司 |
脂质纳米颗粒配制品中的固醇类似物
|
|
WO2025007148A1
(en)
|
2023-06-30 |
2025-01-02 |
Orna Therapeutics, Inc. |
Polymer lipid nanoparticle compositions for delivering circular polynucleotides
|
|
WO2025011529A2
(en)
|
2023-07-07 |
2025-01-16 |
Shanghai Circode Biomed Co., Ltd. |
Circular rna vaccines for seasonal flu and methods of uses
|
|
AU2024299627A1
(en)
|
2023-07-25 |
2026-01-22 |
Flagship Pioneering Innovations Vii, Llc |
Cas endonucleases and related methods
|
|
CN121620589A
(zh)
|
2023-08-01 |
2026-03-06 |
法国居里学院 |
包含编码环gmp-amp合酶的核酸序列的纳米粒子
|
|
WO2025027579A2
(en)
|
2023-08-03 |
2025-02-06 |
BioNTech SE |
Rna compositions targeting hiv
|
|
CN121866336A
(zh)
|
2023-08-03 |
2026-04-14 |
百欧恩泰欧洲股份公司 |
靶向hiv的rna组合物
|
|
WO2025032158A1
(en)
|
2023-08-08 |
2025-02-13 |
Institut National de la Santé et de la Recherche Médicale |
Method to treat tauopathies
|
|
WO2025038864A1
(en)
*
|
2023-08-16 |
2025-02-20 |
Beam Therapeutics Inc. |
Ionizable lipids with linear head groups
|
|
CN117088820B
(zh)
*
|
2023-08-18 |
2025-11-28 |
苏州信使生物科技有限公司 |
一种新型阳离子lnp递送系统及制备方法
|
|
WO2025042786A1
(en)
|
2023-08-18 |
2025-02-27 |
Flagship Pioneering Innovations Vi, Llc |
Compositions comprising circular polyribonucleotides and uses thereof
|
|
CN121752588A
(zh)
|
2023-08-29 |
2026-03-27 |
上海环码生物医药有限公司 |
编码vegf多肽的环状rna、制剂和使用方法
|
|
WO2025049690A1
(en)
|
2023-08-29 |
2025-03-06 |
Orna Therapeutics, Inc. |
Circular polyethylene glycol lipids
|
|
WO2025048714A1
(en)
*
|
2023-08-30 |
2025-03-06 |
Agency For Science, Technology And Research |
A compound for preparing lipid nanoparticles encapsulating an agent, nanoparticle composition comprising said compound and related methods thereof
|
|
IL326647A
(en)
|
2023-09-01 |
2026-04-01 |
Novoarc Gmbh |
Lipid nanoparticles with a nucleic acid charge and an ionizable lipid
|
|
AU2024335327A1
(en)
|
2023-09-01 |
2026-03-26 |
Renagade Therapeutics Management Inc. |
Gene editing systems, compositions, and methods for treatment of vexas syndrome
|
|
WO2025054236A2
(en)
|
2023-09-06 |
2025-03-13 |
Flagship Pioneering Innovations Vii, Llc |
Sars-cov-2 vaccine compositions and related methods
|
|
WO2025052180A2
(en)
|
2023-09-07 |
2025-03-13 |
Axelyf ehf. |
Lipids and lipid nanoparticles
|
|
CN119591513A
(zh)
*
|
2023-09-11 |
2025-03-11 |
苏州星核迪赛生物技术有限公司 |
局部递送药物的材料及其应用
|
|
WO2025062315A2
(en)
|
2023-09-18 |
2025-03-27 |
University Of The Witwatersrand, Johannesburg |
Methods of valorising cashew nut shell liquid (cnsl) and/or a component thereof
|
|
AU2024344058A1
(en)
|
2023-09-18 |
2026-04-02 |
Flagship Pioneering Innovations Vii, Llc |
Ionizable lipidoid compositions and therapeutic uses thereof
|
|
WO2025064850A1
(en)
|
2023-09-22 |
2025-03-27 |
BioNTech SE |
Rna constructs with n-terminal degrons to enhance an immune response
|
|
WO2025072383A1
(en)
|
2023-09-25 |
2025-04-03 |
The Broad Institute, Inc. |
Viral open reading frames, uses thereof, and methods of detecting the same
|
|
WO2025072331A1
(en)
|
2023-09-26 |
2025-04-03 |
Flagship Pioneering Innovations Vii, Llc |
Cas nucleases and related methods
|
|
WO2025073890A1
(en)
|
2023-10-06 |
2025-04-10 |
Institut National de la Santé et de la Recherche Médicale |
Method to capture circulating tumor extracellular vesicles
|
|
WO2025080867A1
(en)
*
|
2023-10-10 |
2025-04-17 |
The Board Of Regents Of The University Of Texas System |
Ionizable lipids for improved mrna delivery
|
|
WO2025081002A1
(en)
|
2023-10-11 |
2025-04-17 |
RNAimmune, Inc. |
Ionizable lipids for the delivery of nucleic acids
|
|
WO2025081042A1
(en)
|
2023-10-12 |
2025-04-17 |
Renagade Therapeutics Management Inc. |
Nickase-retron template-based precision editing system and methods of use
|
|
CN119330848B
(zh)
*
|
2023-10-19 |
2025-07-08 |
仁景(苏州)生物科技有限公司 |
用于递送的脂质化合物及脂质纳米颗粒
|
|
CN119912351A
(zh)
*
|
2023-10-30 |
2025-05-02 |
广州市锐博生物科技有限公司 |
脂质化合物及其组合物
|
|
WO2025096807A2
(en)
|
2023-10-31 |
2025-05-08 |
Flagship Pioneering Innovations Vii, Llc |
Novel therapeutic dna forms
|
|
WO2025096681A1
(en)
*
|
2023-10-31 |
2025-05-08 |
Tiba Biotech Llc |
Novel gene delivery agents
|
|
WO2025097055A2
(en)
|
2023-11-02 |
2025-05-08 |
The Broad Institute, Inc. |
Compositions and methods of use of t cells in immunotherapy
|
|
WO2025101501A1
(en)
|
2023-11-07 |
2025-05-15 |
Orna Therapeutics, Inc. |
Circular rna compositions
|
|
WO2025103803A1
(en)
|
2023-11-13 |
2025-05-22 |
CureVac SE |
Immunotherapy against neuronal and brain tumors
|
|
WO2025106670A1
(en)
|
2023-11-14 |
2025-05-22 |
Flagship Pioneering Innovations Vii, Llc |
Ionizable lipidoid compositions and therapeutic uses thereof
|
|
WO2025106754A1
(en)
|
2023-11-15 |
2025-05-22 |
BioNTech SE |
Coronavirus vaccine
|
|
GB202416789D0
(en)
|
2023-11-15 |
2025-01-01 |
BioNTech SE |
SARS-COV-2 immunogenic compositions
|
|
WO2025104695A1
(en)
*
|
2023-11-16 |
2025-05-22 |
Corti Therapeutics Pte. Ltd. |
Ionizable cationic lipids and lipid nanoparticles thereof
|
|
WO2025106930A1
(en)
|
2023-11-17 |
2025-05-22 |
Sail Biomedicines, Inc. |
Circular polyribonucleotides encoding glucagon-like peptide 2 (glp-2) and uses thereof
|
|
WO2025106915A1
(en)
|
2023-11-17 |
2025-05-22 |
Sail Biomedicines, Inc. |
Circular polyribonucleotides encoding glucagon-like peptide 1 (glp-1) and uses thereof
|
|
WO2025109173A1
(en)
|
2023-11-22 |
2025-05-30 |
Advantage Therapeutics, Inc. |
Nucleic acid encoding klotho for use in therapeutic and non-therapeutic methods for reducing body weight
|
|
US20250161347A1
(en)
|
2023-11-22 |
2025-05-22 |
Flagship Pioneering Innovations Vii, Llc |
Methods and compositions for treating non-alcoholic fatty liver disease
|
|
EP4566618A1
(en)
|
2023-12-06 |
2025-06-11 |
ADvantage Therapeutics, Inc. |
Nucleic acid encoding klotho for use in therapeutic and non-therapeutic methods for reducing body weight
|
|
WO2025117877A2
(en)
|
2023-12-01 |
2025-06-05 |
Flagship Pioneering Innovations Vii, Llc |
Cas nucleases and related methods
|
|
US12364773B2
(en)
|
2023-12-01 |
2025-07-22 |
Recode Therapeutics, Inc. |
Lipid nanoparticle compositions and uses thereof
|
|
US12553042B2
(en)
|
2023-12-01 |
2026-02-17 |
Recode Therapeutics, Inc. |
Method for quantifying an amount of capped messenger RNA
|
|
WO2025128871A2
(en)
|
2023-12-13 |
2025-06-19 |
Renagade Therapeutics Management Inc. |
Lipid nanoparticles comprising coding rna molecules for use in gene editing and as vaccines and therapeutic agents
|
|
WO2025124711A1
(en)
|
2023-12-13 |
2025-06-19 |
BioNTech SE |
Glycolipid compositions
|
|
WO2025124541A1
(zh)
*
|
2023-12-13 |
2025-06-19 |
上海瑞宏迪医药有限公司 |
一种阳离子脂质及其应用
|
|
WO2025129201A1
(en)
|
2023-12-15 |
2025-06-19 |
Capstan Therapeutics, Inc. |
Humanized anti-cd8 antibodies and uses thereof
|
|
WO2025129158A1
(en)
|
2023-12-15 |
2025-06-19 |
The Broad Institute, Inc. |
Engineered arc delivery vesicles and uses thereof
|
|
WO2025133115A1
(en)
|
2023-12-21 |
2025-06-26 |
Ose Immunotherapeutics |
Lipid-based nanoparticles comprising il-35
|
|
WO2025137646A1
(en)
|
2023-12-22 |
2025-06-26 |
Recode Therapeutics, Inc. |
Gene editing methods and compositions for treating cystic fibrosis
|
|
WO2025144938A1
(en)
|
2023-12-26 |
2025-07-03 |
Emmune, Inc. |
Systems for nucleic acid transfer
|
|
WO2025141521A1
(en)
|
2023-12-29 |
2025-07-03 |
Sanofi |
Lipids having dendritic moieties
|
|
WO2025149492A1
(en)
|
2024-01-08 |
2025-07-17 |
BioNTech SE |
Rna encoding an immune inhibitory il-1 family member
|
|
CN118026881A
(zh)
*
|
2024-01-16 |
2024-05-14 |
宁波君健生物科技有限公司 |
一种含有阳离子脂质的纳米脂质颗粒及其应用于自复制mRNA递送系统
|
|
WO2025155753A2
(en)
|
2024-01-17 |
2025-07-24 |
Renagade Therapeutics Management Inc. |
Improved gene editing system, guides, and methods
|
|
WO2025157848A1
(en)
|
2024-01-23 |
2025-07-31 |
Institut National de la Santé et de la Recherche Médicale |
Methods for the intravenous treatment of sanfilippo syndrome type iiib
|
|
TW202545974A
(zh)
|
2024-01-26 |
2025-12-01 |
美商旗艦先鋒創新有限責任（Ｖｉｉ）公司 |
免疫受體抑制蛋白及相關方法
|
|
WO2025160381A1
(en)
|
2024-01-26 |
2025-07-31 |
Modernatx, Inc. |
Methods of preparing lipid nanoparticles
|
|
WO2025166238A1
(en)
|
2024-01-31 |
2025-08-07 |
Orna Therapeutics, Inc. |
Fast-shedding polyethylene glycol lipids
|
|
WO2025174765A1
(en)
|
2024-02-12 |
2025-08-21 |
Renagade Therapeutics Management Inc. |
Lipid nanoparticles comprising coding rna molecules for use in gene editing and as vaccines and therapeutic agents
|
|
WO2025186293A1
(en)
|
2024-03-06 |
2025-09-12 |
Institut National de la Santé et de la Recherche Médicale |
Chmp2b mutants for use for treating infection
|
|
WO2025194019A1
(en)
|
2024-03-14 |
2025-09-18 |
Flagship Pioneering Innovations Vii, Llc |
Methods for treating liver fibrosis and non-alcoholic fatty liver disease
|
|
WO2025196065A1
(en)
|
2024-03-20 |
2025-09-25 |
Sanofi |
Novel homocysteine based lipids and their use for delivery of nucleic acids
|
|
WO2025202213A1
(en)
|
2024-03-26 |
2025-10-02 |
Institut National de la Santé et de la Recherche Médicale |
Lipid nanoparticle loaded with antitumoral agent and functionnalized to target immosuppressive cells
|
|
WO2025210520A1
(en)
|
2024-04-04 |
2025-10-09 |
Genevant Sciences Gmbh |
Lipid nanoparticles for inducing an immunological response
|
|
WO2025210521A1
(en)
|
2024-04-04 |
2025-10-09 |
Genevant Sciences Gmbh |
Lipid nanoparticles for stimulating t cells
|
|
WO2025217275A2
(en)
|
2024-04-10 |
2025-10-16 |
Flagship Pioneering Innovations Vii, Llc |
Immune cell targeted compositions and related methods
|
|
CN118388360B
(zh)
|
2024-04-17 |
2025-04-04 |
北京悦康科创医药科技股份有限公司 |
含有苯环结构的长效脾靶向阳离子脂质化合物、包含其的组合物及用途
|
|
WO2025240680A1
(en)
|
2024-05-16 |
2025-11-20 |
Flagship Pioneering Innovations Vii, Llc |
Immunoreceptor inhibitory proteins and related methods
|
|
WO2025240946A1
(en)
|
2024-05-17 |
2025-11-20 |
Intellia Therapeutics, Inc. |
Lipid nanoparticles and lipid nanoparticle compositions
|
|
WO2025245188A2
(en)
|
2024-05-21 |
2025-11-27 |
Flagship Pioneering Innovations Vii, Llc |
Methods of treating liver steatosis and non-alcoholic fatty liver disease
|
|
WO2025245111A1
(en)
|
2024-05-22 |
2025-11-27 |
Flagship Pioneering Innovations Vii, Llc |
Immunoreceptor targeting proteins and related methods
|
|
WO2025250751A1
(en)
|
2024-05-31 |
2025-12-04 |
Orna Therapeutics, Inc. |
Circular rna compositions and methods
|
|
US20260000702A1
(en)
|
2024-06-26 |
2026-01-01 |
Flagship Pioneering Innovations Vii, Llc |
Therapeutic circular dna forms
|
|
WO2026003582A2
(en)
|
2024-06-27 |
2026-01-02 |
Axelyf ehf. |
Lipids and lipid nanoparticles
|
|
WO2026008743A1
(en)
|
2024-07-02 |
2026-01-08 |
Sanofi Pasteur Inc. |
Water-soluble polyanionic polymer as adjuvant for carrier-formulated nucleic acid
|
|
WO2026033123A1
(en)
|
2024-08-08 |
2026-02-12 |
Sanofi Pasteur Inc. |
Lipid nanoparticle formulations for mrna delivery
|
|
WO2026047603A1
(en)
|
2024-08-28 |
2026-03-05 |
BioNTech SE |
Sars-cov-2 immunogenic compositions
|
|
WO2026047148A1
(en)
|
2024-08-29 |
2026-03-05 |
BioNTech SE |
Minimal polypeptide-encoding rnas
|
|
WO2026053147A1
(en)
|
2024-09-05 |
2026-03-12 |
Sanofi Pasteur Inc. |
Helper lipids and lnp compositions comprising same
|
|
WO2026055547A1
(en)
|
2024-09-06 |
2026-03-12 |
Flagship Pioneering Innovations Vii, Llc |
Dna compositions and related methods
|
|
WO2026055543A1
(en)
|
2024-09-06 |
2026-03-12 |
Flagship Pioneering Innovations Vii, Llc |
Modified dna compositions and related methods
|
|
WO2026057625A1
(en)
|
2024-09-11 |
2026-03-19 |
BioNTech SE |
Peptidoglycan hydrolases having a chap domain with engineered active site
|
|
WO2026057626A1
(en)
|
2024-09-11 |
2026-03-19 |
BioNTech SE |
Peptidoglycan hydrolases having multiple enzymatically active domains
|
|
WO2026064313A1
(en)
|
2024-09-17 |
2026-03-26 |
Flagship Pioneering Innovations Vii, Llc |
Rna compositions and related methods
|
|
WO2026064512A1
(en)
|
2024-09-18 |
2026-03-26 |
Generation Bio Co. |
Polyglycerol-conjugated lipids and lipid nanoparticle compositions comprising the same
|
|
WO2026068705A1
(en)
|
2024-09-26 |
2026-04-02 |
Ose Immunotherapeutics |
Lipid-based nanoparticles comprising non-glycosylated fc domains and uses thereof
|
|
WO2026068864A1
(en)
|
2024-09-30 |
2026-04-02 |
BioNTech SE |
Engineered ch1 and cl domains for the prevention of chain mispairing
|