JP2011507534A5 - - Google Patents
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- JP2011507534A5 JP2011507534A5 JP2010539978A JP2010539978A JP2011507534A5 JP 2011507534 A5 JP2011507534 A5 JP 2011507534A5 JP 2010539978 A JP2010539978 A JP 2010539978A JP 2010539978 A JP2010539978 A JP 2010539978A JP 2011507534 A5 JP2011507534 A5 JP 2011507534A5
- Authority
- JP
- Japan
- Prior art keywords
- lipid
- nucleic acid
- particle
- sirna molecule
- modified sirna
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US1707507P | 2007-12-27 | 2007-12-27 | |
| US61/017,075 | 2007-12-27 | ||
| US4522808P | 2008-04-15 | 2008-04-15 | |
| US61/045,228 | 2008-04-15 | ||
| US10065308P | 2008-09-26 | 2008-09-26 | |
| US61/100,653 | 2008-09-26 | ||
| PCT/CA2008/002285 WO2009082817A1 (en) | 2007-12-27 | 2008-12-23 | Silencing of polo-like kinase expression using interfering rna |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2011507534A JP2011507534A (ja) | 2011-03-10 |
| JP2011507534A5 true JP2011507534A5 (https=) | 2012-02-16 |
| JP5697988B2 JP5697988B2 (ja) | 2015-04-08 |
Family
ID=40823727
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010539978A Expired - Fee Related JP5697988B2 (ja) | 2007-12-27 | 2008-12-23 | 干渉ｒｎａを使用したポロ様キナーゼ発現のサイレンシング方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US9006191B2 (https=) |
| EP (1) | EP2238251B1 (https=) |
| JP (1) | JP5697988B2 (https=) |
| AU (1) | AU2008342535B2 (https=) |
| CA (1) | CA2710713C (https=) |
| ES (1) | ES2535419T3 (https=) |
| WO (1) | WO2009082817A1 (https=) |
Families Citing this family (153)
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| US9005654B2 (en) | 2005-07-27 | 2015-04-14 | Protiva Biotherapeutics, Inc. | Systems and methods for manufacturing liposomes |
| US20070054873A1 (en) * | 2005-08-26 | 2007-03-08 | Protiva Biotherapeutics, Inc. | Glucocorticoid modulation of nucleic acid-mediated immune stimulation |
| WO2007048046A2 (en) * | 2005-10-20 | 2007-04-26 | Protiva Biotherapeutics, Inc. | Sirna silencing of filovirus gene expression |
| US8101741B2 (en) * | 2005-11-02 | 2012-01-24 | Protiva Biotherapeutics, Inc. | Modified siRNA molecules and uses thereof |
| US8598333B2 (en) * | 2006-05-26 | 2013-12-03 | Alnylam Pharmaceuticals, Inc. | SiRNA silencing of genes expressed in cancer |
| US7915399B2 (en) * | 2006-06-09 | 2011-03-29 | Protiva Biotherapeutics, Inc. | Modified siRNA molecules and uses thereof |
| US20080311040A1 (en) * | 2007-03-06 | 2008-12-18 | Flagship Ventures | METHODS AND COMPOSITIONS FOR IMPROVED THERAPEUTIC EFFECTS WITH siRNA |
| EP2848688A1 (en) * | 2007-12-10 | 2015-03-18 | Alnylam Pharmaceuticals, Inc. | Compositions and methods for inhibiting expression of factor VII gene |
| WO2009082817A1 (en) * | 2007-12-27 | 2009-07-09 | Protiva Biotherapeutics, Inc. | Silencing of polo-like kinase expression using interfering rna |
| WO2009086558A1 (en) | 2008-01-02 | 2009-07-09 | Tekmira Pharmaceuticals Corporation | Improved compositions and methods for the delivery of nucleic acids |
| AU2009238175C1 (en) * | 2008-04-15 | 2023-11-30 | Arbutus Biopharma Corporation | Novel lipid formulations for nucleic acid delivery |
| CN104119242B (zh) | 2008-10-09 | 2017-07-07 | 泰米拉制药公司 | 改善的氨基脂质和递送核酸的方法 |
| ES2613498T3 (es) * | 2009-07-01 | 2017-05-24 | Protiva Biotherapeutics Inc. | Nuevas formulaciones de lípidos para el suministro de agentes terapéuticos a tumores sólidos |
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-
2008
- 2008-12-23 WO PCT/CA2008/002285 patent/WO2009082817A1/en not_active Ceased
- 2008-12-23 US US12/343,342 patent/US9006191B2/en active Active
- 2008-12-23 EP EP20080867007 patent/EP2238251B1/en active Active
- 2008-12-23 AU AU2008342535A patent/AU2008342535B2/en not_active Ceased
- 2008-12-23 CA CA2710713A patent/CA2710713C/en active Active
- 2008-12-23 JP JP2010539978A patent/JP5697988B2/ja not_active Expired - Fee Related
- 2008-12-23 ES ES08867007.0T patent/ES2535419T3/es active Active
-
2015
- 2015-03-04 US US14/638,885 patent/US20160115483A1/en not_active Abandoned
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