JP2018512373A - Kras突然変異に関連する悪性腫瘍に対する治療のための方法及び組成物 - Google Patents
Kras突然変異に関連する悪性腫瘍に対する治療のための方法及び組成物 Download PDFInfo
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- JP2018512373A JP2018512373A JP2017534275A JP2017534275A JP2018512373A JP 2018512373 A JP2018512373 A JP 2018512373A JP 2017534275 A JP2017534275 A JP 2017534275A JP 2017534275 A JP2017534275 A JP 2017534275A JP 2018512373 A JP2018512373 A JP 2018512373A
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- A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
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Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2014266198 | 2014-12-26 | ||
| JP2014266198 | 2014-12-26 | ||
| US201562184204P | 2015-06-24 | 2015-06-24 | |
| US62/184,204 | 2015-06-24 | ||
| US201562266672P | 2015-12-13 | 2015-12-13 | |
| US62/266,672 | 2015-12-13 | ||
| PCT/US2015/067559 WO2016106404A2 (en) | 2014-12-26 | 2015-12-28 | Methods and compositions for treating malignant tumors associated with kras mutation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JP2018512373A true JP2018512373A (ja) | 2018-05-17 |
Family
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Family Applications (10)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017534275A Pending JP2018512373A (ja) | 2014-12-26 | 2015-12-28 | Kras突然変異に関連する悪性腫瘍に対する治療のための方法及び組成物 |
| JP2017534279A Active JP6865169B2 (ja) | 2014-12-26 | 2015-12-28 | P21遺伝子調節のためのrna干渉剤 |
| JP2017534287A Pending JP2018513669A (ja) | 2014-12-26 | 2015-12-28 | Gst−pi遺伝子調節のためのrna剤 |
| JP2017534294A Active JP6730285B2 (ja) | 2014-12-26 | 2015-12-28 | Rna干渉組成物及び悪性腫瘍のための方法 |
| JP2017534286A Active JP6793649B2 (ja) | 2014-12-26 | 2015-12-28 | P21遺伝子調節のためのrna剤 |
| JP2017534274A Pending JP2018513104A (ja) | 2014-12-26 | 2015-12-28 | Hsp47及びp21を標的とするrnai分子による悪性腫瘍の治療用組成物及び方法 |
| JP2017534297A Active JP6457645B2 (ja) | 2014-12-26 | 2015-12-28 | GST−π遺伝子を調節するためのRNA干渉剤 |
| JP2021183788A Active JP7307137B2 (ja) | 2014-12-26 | 2021-11-11 | GST-π遺伝子を調節するためのRNA干渉剤 |
| JP2023106970A Active JP7655971B2 (ja) | 2014-12-26 | 2023-06-29 | GST-π遺伝子を調節するためのRNA干渉剤 |
| JP2025046972A Pending JP2025102833A (ja) | 2014-12-26 | 2025-03-21 | GST-π遺伝子を調節するためのRNA干渉剤 |
Family Applications After (9)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017534279A Active JP6865169B2 (ja) | 2014-12-26 | 2015-12-28 | P21遺伝子調節のためのrna干渉剤 |
| JP2017534287A Pending JP2018513669A (ja) | 2014-12-26 | 2015-12-28 | Gst−pi遺伝子調節のためのrna剤 |
| JP2017534294A Active JP6730285B2 (ja) | 2014-12-26 | 2015-12-28 | Rna干渉組成物及び悪性腫瘍のための方法 |
| JP2017534286A Active JP6793649B2 (ja) | 2014-12-26 | 2015-12-28 | P21遺伝子調節のためのrna剤 |
| JP2017534274A Pending JP2018513104A (ja) | 2014-12-26 | 2015-12-28 | Hsp47及びp21を標的とするrnai分子による悪性腫瘍の治療用組成物及び方法 |
| JP2017534297A Active JP6457645B2 (ja) | 2014-12-26 | 2015-12-28 | GST−π遺伝子を調節するためのRNA干渉剤 |
| JP2021183788A Active JP7307137B2 (ja) | 2014-12-26 | 2021-11-11 | GST-π遺伝子を調節するためのRNA干渉剤 |
| JP2023106970A Active JP7655971B2 (ja) | 2014-12-26 | 2023-06-29 | GST-π遺伝子を調節するためのRNA干渉剤 |
| JP2025046972A Pending JP2025102833A (ja) | 2014-12-26 | 2025-03-21 | GST-π遺伝子を調節するためのRNA干渉剤 |
Country Status (10)
| Country | Link |
|---|---|
| US (14) | US10264976B2 (enExample) |
| EP (9) | EP3236975A4 (enExample) |
| JP (10) | JP2018512373A (enExample) |
| KR (4) | KR20170098929A (enExample) |
| CN (7) | CN107106564A (enExample) |
| AU (4) | AU2015369596A1 (enExample) |
| BR (2) | BR112017013597B1 (enExample) |
| CA (4) | CA2972265A1 (enExample) |
| RU (4) | RU2719185C2 (enExample) |
| WO (7) | WO2016106405A1 (enExample) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2018512110A (ja) * | 2014-12-26 | 2018-05-17 | 日東電工株式会社 | GST−π遺伝子を調節するためのRNA干渉剤 |
| JP2018183163A (ja) * | 2014-12-26 | 2018-11-22 | 日東電工株式会社 | GST−π遺伝子を調節するためのRNA干渉剤 |
| US11045488B2 (en) | 2014-12-26 | 2021-06-29 | Nitto Denko Corporation | RNA interference agents for GST-π gene modulation |
| JP2022512077A (ja) * | 2018-11-16 | 2022-02-02 | 日東電工株式会社 | Rna干渉送達製剤及び悪性腫瘍のための方法 |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10792299B2 (en) | 2014-12-26 | 2020-10-06 | Nitto Denko Corporation | Methods and compositions for treating malignant tumors associated with kras mutation |
| US20180002702A1 (en) * | 2014-12-26 | 2018-01-04 | Nitto Denko Corporation | Methods and compositions for treating malignant tumors associated with kras mutation |
| WO2016210190A1 (en) | 2015-06-24 | 2016-12-29 | Nitto Denko Corporation | Ionizable compounds and compositions and uses thereof |
| CN108367022A (zh) * | 2015-12-13 | 2018-08-03 | 日东电工株式会社 | 具有高活性和降低脱靶的sirna结构 |
| TWI780046B (zh) | 2016-05-10 | 2022-10-11 | 國立大學法人東京醫科齒科大學 | 炎症促進因子表現抑制劑、其有效成分之篩選方法、對於該方法為有用之表現匣、診斷藥及診斷方法 |
| WO2018151840A2 (en) * | 2017-02-16 | 2018-08-23 | Nitto Denko Corporation | Methods and compositions for treating malignant tumors |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| JP2022036954A (ja) * | 2014-12-26 | 2022-03-08 | 日東電工株式会社 | GST-π遺伝子を調節するためのRNA干渉剤 |
| JP2018183163A (ja) * | 2014-12-26 | 2018-11-22 | 日東電工株式会社 | GST−π遺伝子を調節するためのRNA干渉剤 |
| JP2019187438A (ja) * | 2014-12-26 | 2019-10-31 | 日東電工株式会社 | GST−π遺伝子を調節するためのRNA干渉剤 |
| JP2021006030A (ja) * | 2014-12-26 | 2021-01-21 | 日東電工株式会社 | GST−π遺伝子を調節するためのRNA干渉剤 |
| US11045488B2 (en) | 2014-12-26 | 2021-06-29 | Nitto Denko Corporation | RNA interference agents for GST-π gene modulation |
| JP2018512110A (ja) * | 2014-12-26 | 2018-05-17 | 日東電工株式会社 | GST−π遺伝子を調節するためのRNA干渉剤 |
| USRE49431E1 (en) | 2014-12-26 | 2023-02-28 | Nitto Denko Corporation | RNA interference agents for GST-PI gene modulation |
| JP7307137B2 (ja) | 2014-12-26 | 2023-07-11 | 日東電工株式会社 | GST-π遺伝子を調節するためのRNA干渉剤 |
| JP2022512077A (ja) * | 2018-11-16 | 2022-02-02 | 日東電工株式会社 | Rna干渉送達製剤及び悪性腫瘍のための方法 |
| JP2023093769A (ja) * | 2018-11-16 | 2023-07-04 | 日東電工株式会社 | Rna干渉送達製剤及び悪性腫瘍のための方法 |
| US11708575B2 (en) | 2018-11-16 | 2023-07-25 | Nitto Denko Corporation | RNA interference delivery formulation and methods for malignant tumors |
| TWI840449B (zh) * | 2018-11-16 | 2024-05-01 | 日商日東電工股份有限公司 | 用於惡性腫瘤之rna干擾輸送配方及方法 |
| JP7667077B2 (ja) | 2018-11-16 | 2025-04-22 | 日東電工株式会社 | Rna干渉送達製剤及び悪性腫瘍のための方法 |
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