US9393315B2 - Compounds for targeting drug delivery and enhancing siRNA activity - Google Patents

Compounds for targeting drug delivery and enhancing siRNA activity Download PDF

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Publication number
US9393315B2
US9393315B2 US13/492,424 US201213492424A US9393315B2 US 9393315 B2 US9393315 B2 US 9393315B2 US 201213492424 A US201213492424 A US 201213492424A US 9393315 B2 US9393315 B2 US 9393315B2
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United States
Prior art keywords
peg
lys
retinoid
amido
compound
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Active
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US13/492,424
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US20130017249A1 (en
Inventor
Yoshiro Niitsu
Joseph E. Payne
John A. Gaudette
Zheng Hou
Victor Knopov
Richard P. Witte
Mohammad Ahmadian
Loren A. Perelman
Yasunobu Tanaka
Violetta Akopian
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Nitto Denko Corp
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Nitto Denko Corp
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Priority to US201161494840P priority Critical
Priority to US13/492,424 priority patent/US9393315B2/en
Application filed by Nitto Denko Corp filed Critical Nitto Denko Corp
Assigned to NITTO DENKO CORPORATION reassignment NITTO DENKO CORPORATION ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: HOU, ZHENG, PERELMAN, Loren A., AKOPIAN, Violetta, GAUDETTE, John A., NIITSU, YOSHIRO, AHMADIAN, MOHAMMAD, KNOPOV, VICTOR, PAYNE, JOSEPH E., WITTE, Richard P., TANAKA, YASUNOBU
Publication of US20130017249A1 publication Critical patent/US20130017249A1/en
Priority claimed from US13/786,883 external-priority patent/US20130171240A1/en
Priority claimed from US13/789,032 external-priority patent/US20160015656A2/en
Priority claimed from US13/836,060 external-priority patent/US20130210744A1/en
Priority claimed from US14/668,618 external-priority patent/US20150259683A1/en
Publication of US9393315B2 publication Critical patent/US9393315B2/en
Application granted granted Critical
Priority claimed from US15/284,494 external-priority patent/US10196637B2/en
Application status is Active legal-status Critical
Anticipated expiration legal-status Critical

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