|
CA2691357C
(en)
|
2007-06-18 |
2014-09-23 |
N.V. Organon |
Antibodies to human programmed death receptor pd-1
|
|
ES2671748T3
(es)
|
2011-07-21 |
2018-06-08 |
Tolero Pharmaceuticals, Inc. |
Inhibidores heterocíclicos de proteína quinasas
|
|
US12466897B2
(en)
|
2011-10-10 |
2025-11-11 |
Xencor, Inc. |
Heterodimeric human IgG1 polypeptides with isoelectric point modifications
|
|
UA117466C2
(uk)
|
2012-12-13 |
2018-08-10 |
Мерк Шарп Енд Доме Корп. |
СТАБІЛЬНИЙ СКЛАД У ВИГЛЯДІ РОЗЧИНУ АНТИТІЛА ДО IL-23p19
|
|
EP3620473A1
(en)
|
2013-01-14 |
2020-03-11 |
Xencor, Inc. |
Novel heterodimeric proteins
|
|
US9605084B2
(en)
|
2013-03-15 |
2017-03-28 |
Xencor, Inc. |
Heterodimeric proteins
|
|
US10487155B2
(en)
|
2013-01-14 |
2019-11-26 |
Xencor, Inc. |
Heterodimeric proteins
|
|
US11053316B2
(en)
|
2013-01-14 |
2021-07-06 |
Xencor, Inc. |
Optimized antibody variable regions
|
|
US10968276B2
(en)
|
2013-03-12 |
2021-04-06 |
Xencor, Inc. |
Optimized anti-CD3 variable regions
|
|
US10858417B2
(en)
|
2013-03-15 |
2020-12-08 |
Xencor, Inc. |
Heterodimeric proteins
|
|
EP3049442A4
(en)
|
2013-09-26 |
2017-06-28 |
Costim Pharmaceuticals Inc. |
Methods for treating hematologic cancers
|
|
AU2014361473B2
(en)
|
2013-12-12 |
2019-09-26 |
Jiangsu Hengrui Medicine Co., Ltd. |
PD-1 antibody, antigen-binding fragment thereof, and medical application thereof
|
|
JOP20200094A1
(ar)
|
2014-01-24 |
2017-06-16 |
Dana Farber Cancer Inst Inc |
جزيئات جسم مضاد لـ pd-1 واستخداماتها
|
|
JOP20200096A1
(ar)
|
2014-01-31 |
2017-06-16 |
Children’S Medical Center Corp |
جزيئات جسم مضاد لـ tim-3 واستخداماتها
|
|
US20150259420A1
(en)
|
2014-03-14 |
2015-09-17 |
Novartis Ag |
Antibody molecules to lag-3 and uses thereof
|
|
KR20230022270A
(ko)
|
2014-03-28 |
2023-02-14 |
젠코어 인코포레이티드 |
Cd38 및 cd3에 결합하는 이중특이적 항체
|
|
RS61678B1
(sr)
|
2014-05-28 |
2021-05-31 |
Agenus Inc |
Anti-gitr antitela i postupci za njihovu primenu
|
|
TWI693232B
(zh)
|
2014-06-26 |
2020-05-11 |
美商宏觀基因股份有限公司 |
與pd-1和lag-3具有免疫反應性的共價結合的雙抗體和其使用方法
|
|
JO3663B1
(ar)
*
|
2014-08-19 |
2020-08-27 |
Merck Sharp & Dohme |
الأجسام المضادة لمضاد lag3 وأجزاء ربط الأنتيجين
|
|
US20170281624A1
(en)
|
2014-09-13 |
2017-10-05 |
Novartis Ag |
Combination therapies of alk inhibitors
|
|
EP3662903A3
(en)
*
|
2014-10-03 |
2020-10-14 |
Novartis AG |
Combination therapies
|
|
ES2952717T3
(es)
|
2014-10-14 |
2023-11-03 |
Novartis Ag |
Moléculas de anticuerpos contra PD-L1 y usos de las mismas
|
|
US10259887B2
(en)
|
2014-11-26 |
2019-04-16 |
Xencor, Inc. |
Heterodimeric antibodies that bind CD3 and tumor antigens
|
|
CU24597B1
(es)
|
2014-11-26 |
2022-05-11 |
Xencor Inc |
Anticuerpos biespecíficos heterodiméricos que se unen a cd3 y cd20
|
|
BR112017011166A2
(pt)
|
2014-11-26 |
2018-02-27 |
Xencor, Inc. |
anticorpos heterodiméricos que se ligam a cd3 e cd38
|
|
US10428155B2
(en)
|
2014-12-22 |
2019-10-01 |
Xencor, Inc. |
Trispecific antibodies
|
|
PT3653221T
(pt)
|
2015-02-19 |
2022-11-08 |
Compugen Ltd |
Anticorpos anti-pvrig e métodos de utilização
|
|
CN115109158A
(zh)
|
2015-05-07 |
2022-09-27 |
阿吉纳斯公司 |
抗ox40抗体及其使用方法
|
|
EP3298021B1
(en)
|
2015-05-18 |
2019-05-01 |
Tolero Pharmaceuticals, Inc. |
Alvocidib prodrugs having increased bioavailability
|
|
EP3303394B1
(en)
|
2015-05-29 |
2020-04-08 |
Agenus Inc. |
Anti-ctla-4 antibodies and methods of use thereof
|
|
TWI773646B
(zh)
|
2015-06-08 |
2022-08-11 |
美商宏觀基因股份有限公司 |
結合lag-3的分子和其使用方法
|
|
AU2016293674B2
(en)
*
|
2015-07-16 |
2019-11-21 |
Bioxcel Therapeutics, Inc. |
A novel approach for treatment of cancer using immunomodulation
|
|
TWI886756B
(zh)
|
2015-07-30 |
2025-06-11 |
美商宏觀基因股份有限公司 |
Pd-1結合分子和其使用方法
|
|
IL257110B
(en)
|
2015-10-02 |
2022-09-01 |
Hoffmann La Roche |
Bispecific antibodies specific against pd1 and tim3
|
|
TWI756187B
(zh)
|
2015-10-09 |
2022-03-01 |
美商再生元醫藥公司 |
抗ｌａｇ３抗體及其用途
|
|
CN116063542A
(zh)
|
2015-12-02 |
2023-05-05 |
阿吉纳斯公司 |
抗体和其使用方法
|
|
US10227410B2
(en)
|
2015-12-07 |
2019-03-12 |
Xencor, Inc. |
Heterodimeric antibodies that bind CD3 and PSMA
|
|
MA44082A
(fr)
|
2015-12-14 |
2018-10-24 |
Macrogenics Inc |
Molécules bispécifiques présentant une immunoréactivité par rapport à pd-1 et à ctla-4 et leurs procédés d'utilisation
|
|
WO2017106129A1
(en)
*
|
2015-12-16 |
2017-06-22 |
Merck Sharp & Dohme Corp. |
Anti-lag3 antibodies and antigen-binding fragments
|
|
JP7328762B2
(ja)
*
|
2016-02-26 |
2023-08-17 |
ザ ユニヴァーシティ オブ ウェスタン オンタリオ |
抗ＣＤ１１ｄ抗体およびその使用
|
|
US11559510B2
(en)
|
2016-04-06 |
2023-01-24 |
Noxopharm Limited |
Isoflavonoid composition with improved pharmacokinetics
|
|
TWI794171B
(zh)
|
2016-05-11 |
2023-03-01 |
美商滬亞生物國際有限公司 |
Ｈｄａｃ抑制劑與ｐｄ-ｌ１抑制劑之組合治療
|
|
TWI808055B
(zh)
|
2016-05-11 |
2023-07-11 |
美商滬亞生物國際有限公司 |
Hdac 抑制劑與 pd-1 抑制劑之組合治療
|
|
KR102419412B1
(ko)
*
|
2016-05-18 |
2022-07-12 |
베링거 인겔하임 인터내셔날 게엠베하 |
암 치료용 항-pd1 및 항-lag3 항체
|
|
US12202856B2
(en)
|
2016-05-19 |
2025-01-21 |
The General Hospital Corporation |
Tethered interleukin-2 to its receptor IL-2RBETA, a platform to enhance natural killer and regulatory T cell activity
|
|
KR102366813B1
(ko)
|
2016-05-27 |
2022-02-24 |
아게누스 인코포레이티드 |
항-tim-3 항체 및 이의 사용 방법
|
|
EP3468581A1
(en)
|
2016-06-13 |
2019-04-17 |
Torque Therapeutics, Inc. |
Methods and compositions for promoting immune cell function
|
|
US10787518B2
(en)
|
2016-06-14 |
2020-09-29 |
Xencor, Inc. |
Bispecific checkpoint inhibitor antibodies
|
|
CN109311993B
(zh)
|
2016-06-20 |
2022-12-20 |
F-星治疗有限公司 |
Lag-3结合元件
|
|
US11214620B2
(en)
|
2016-06-20 |
2022-01-04 |
F-Star Therapeutics Limited |
Binding molecules binding PD-L1 and LAG-3
|
|
RU2769282C2
(ru)
|
2016-06-20 |
2022-03-30 |
Кимаб Лимитед |
Анти-PD-L1 и IL-2 цитокины
|
|
KR102497259B1
(ko)
*
|
2016-06-23 |
2023-02-07 |
지앙수 헨그루이 파마슈티컬스 컴퍼니 리미티드 |
Ｌａｇ―３ 항체, 이의 항원-결합 단편 및 이의 약학적 용도
|
|
EP4050032A1
(en)
|
2016-06-28 |
2022-08-31 |
Xencor, Inc. |
Heterodimeric antibodies that bind somatostatin receptor 2
|
|
GB201612520D0
(en)
|
2016-07-19 |
2016-08-31 |
F-Star Beta Ltd |
Binding molecules
|
|
NL2017270B1
(en)
*
|
2016-08-02 |
2018-02-09 |
Aduro Biotech Holdings Europe B V |
New anti-hCTLA-4 antibodies
|
|
CA3033904A1
(en)
*
|
2016-08-15 |
2018-02-22 |
National University Corporation Hokkaido University |
Anti-lag-3 antibody
|
|
KR20230145510A
(ko)
|
2016-08-17 |
2023-10-17 |
컴퓨젠 엘티디. |
항-tigit 항체, 항-pvrig 항체 및 이들의 조합
|
|
US10793632B2
(en)
|
2016-08-30 |
2020-10-06 |
Xencor, Inc. |
Bispecific immunomodulatory antibodies that bind costimulatory and checkpoint receptors
|
|
MY190805A
(en)
*
|
2016-09-08 |
2022-05-12 |
Daiichi Sankyo Co Ltd |
Antibody for treating autoimmune diseases
|
|
NZ792355A
(en)
|
2016-10-11 |
2025-12-19 |
Agenus Inc |
Anti-lag-3 antibodies and methods of use thereof
|
|
MA46525A
(fr)
*
|
2016-10-13 |
2019-08-21 |
Symphogen As |
Anticorps anti-lag-3 et compositions
|
|
KR102562519B1
(ko)
|
2016-10-14 |
2023-08-02 |
젠코어 인코포레이티드 |
IL-15/IL-15Rα FC-융합 단백질 및 PD-1 항체 단편을 포함하는 이중특이성 이종이량체 융합 단백질
|
|
MX2019004957A
(es)
*
|
2016-10-28 |
2019-06-24 |
Merck Sharp & Dohme |
Proceso de purificacion para la eliminacion de variantes de anticuerpos con sulfatacion de tirosina; composiciones purificadas.
|
|
AU2017359467A1
(en)
|
2016-11-09 |
2019-05-02 |
Agenus Inc. |
Anti-OX40 antibodies, anti-GITR antibodies, and methods of use thereof
|
|
WO2018094275A1
(en)
|
2016-11-18 |
2018-05-24 |
Tolero Pharmaceuticals, Inc. |
Alvocidib prodrugs and their use as protein kinase inhibitors
|
|
SG10201912560YA
(en)
|
2016-12-07 |
2020-02-27 |
Agenus Inc |
Anti-ctla-4 antibodies and methods of use thereof
|
|
CN108204958A
(zh)
*
|
2016-12-19 |
2018-06-26 |
伊缪泰普有限公司 |
结合测定
|
|
JP7780248B2
(ja)
*
|
2017-01-06 |
2025-12-04 |
アイオバンス バイオセラピューティクス，インコーポレイテッド |
腫瘍壊死因子受容体スーパーファミリー（ｔｎｆｒｓｆ）アゴニストによる腫瘍浸潤リンパ球（ｔｉｌ）の拡大培養及びｔｉｌとｔｎｆｒｓｆアゴニストとの治療的併用
|
|
JP7300394B2
(ja)
|
2017-01-17 |
2023-06-29 |
ヘパリジェニックス ゲーエムベーハー |
肝再生の促進又は肝細胞死の低減もしくは予防のためのプロテインキナーゼ阻害
|
|
CA3053010A1
(en)
|
2017-02-08 |
2018-08-16 |
Dragonfly Therapeutics, Inc. |
Multi-specific binding proteins for activation of natural killer cells and therapeutic uses thereof to treat cancer
|
|
MX2019009565A
(es)
|
2017-02-10 |
2020-02-24 |
Regeneron Pharma |
Anticuerpos anti-lag3 radiomarcados para la obtención de imágenes mediante inmuno-pet.
|
|
JP7685821B2
(ja)
|
2017-02-20 |
2025-05-30 |
ドラゴンフライ セラピューティクス， インコーポレイテッド |
Ｈｅｒ２、ＮＫＧ２ＤおよびＣＤ１６に結合するタンパク質
|
|
SG11201907561PA
(en)
*
|
2017-02-22 |
2019-09-27 |
I Mab |
Anti-lag-3 antibodies and uses thereof
|
|
WO2018184964A1
(en)
|
2017-04-03 |
2018-10-11 |
F. Hoffmann-La Roche Ag |
Immunoconjugates of an anti-pd-1 antibody with a mutant il-2 or with il-15
|
|
MY204068A
(en)
|
2017-04-05 |
2024-08-06 |
Servier Lab |
Combination therapies targeting pd-1, tim-3, and lag-3
|
|
KR102294136B1
(ko)
*
|
2017-04-05 |
2021-08-26 |
에프. 호프만-라 로슈 아게 |
항-lag3 항체
|
|
IL268527B2
(en)
|
2017-04-05 |
2024-03-01 |
Hoffmann La Roche |
Bispecific antibodies specifically binding to pd1 and lag3
|
|
TWI796329B
(zh)
|
2017-04-07 |
2023-03-21 |
美商默沙東有限責任公司 |
抗－ilt4抗體及抗原結合片段
|
|
EP3615572A1
(en)
*
|
2017-04-27 |
2020-03-04 |
Tesaro Inc. |
Antibody agents directed against lymphocyte activation gene-3 (lag-3) and uses thereof
|
|
AR111651A1
(es)
|
2017-04-28 |
2019-08-07 |
Novartis Ag |
Conjugados de anticuerpos que comprenden agonistas del receptor de tipo toll y terapias de combinación
|
|
JOP20190260A1
(ar)
|
2017-05-02 |
2019-10-31 |
Merck Sharp & Dohme |
صيغ ثابتة لأجسام مضادة لمستقبل الموت المبرمج 1 (pd-1) وطرق استخدامها
|
|
CA3060581A1
(en)
*
|
2017-05-02 |
2018-11-08 |
Merck Sharp & Dohme Corp. |
Formulations of anti-lag3 antibodies and co-formulations of anti-lag3 antibodies and anti-pd-1 antibodies
|
|
EP3621642B1
(en)
*
|
2017-05-10 |
2024-09-18 |
Zhejiang Shimai Pharmaceutical Co., Ltd. |
Human monoclonal antibodies against lag3 and uses thereof
|
|
CA3060989A1
(en)
|
2017-05-30 |
2018-12-06 |
Bristol-Myers Squibb Company |
Compositions comprising a combination of an anti-lag-3 antibody, a pd-1 pathway inhibitor, and an immunotherapeutic agent
|
|
CA3060984A1
(en)
|
2017-05-30 |
2018-12-06 |
Bristol-Myers Squibb Company |
Treatment of lag-3 positive tumors
|
|
JP7301002B2
(ja)
|
2017-05-30 |
2023-06-30 |
ブリストル－マイヤーズ スクイブ カンパニー |
抗ｌａｇ－３抗体または抗ｌａｇ－３抗体および抗ｐｄ－１もしくは抗ｐｄ－ｌ１抗体を含む組成物
|
|
US20230042913A1
(en)
*
|
2017-06-05 |
2023-02-09 |
The Council Of The Queensland Institute Of Medical Research |
A combination of, or a bispecific binding molecule to, an immune checkpoint molecule antagonist and a rank-l (nf-kb ligand) antagonist for cancer therapy or prophylaxis and uses thereof
|
|
WO2018229715A1
(en)
|
2017-06-16 |
2018-12-20 |
Novartis Ag |
Compositions comprising anti-cd32b antibodies and methods of use thereof
|
|
WO2018235056A1
(en)
|
2017-06-22 |
2018-12-27 |
Novartis Ag |
Il-1beta binding antibodies for use in treating cancer
|
|
AU2018287519B2
(en)
|
2017-06-22 |
2021-07-22 |
Novartis Ag |
IL-1beta binding antibodies for use in treating cancer
|
|
PE20200717A1
(es)
|
2017-06-22 |
2020-07-21 |
Novartis Ag |
Moleculas de anticuerpo que se unen a cd73 y usos de las mismas
|
|
AU2018292618A1
(en)
|
2017-06-27 |
2019-12-19 |
Novartis Ag |
Dosage regimens for anti-TIM-3 antibodies and uses thereof
|
|
IL271833B2
(en)
*
|
2017-07-06 |
2024-09-01 |
Merus Nv |
Antibodies that modulate a biological activity expressed by a cell
|
|
CN110914303B
(zh)
*
|
2017-07-13 |
2023-06-02 |
南京维立志博生物科技有限公司 |
结合lag-3的抗体及其用途
|
|
KR20200031659A
(ko)
|
2017-07-20 |
2020-03-24 |
노파르티스 아게 |
항-lag-3 항체의 투여 요법 및 그의 용도
|
|
CA3070446A1
(en)
|
2017-07-25 |
2019-01-31 |
Immutics, Inc. |
Treating cancer by blocking the interaction of tim-3 and its ligand
|
|
AU2018323955A1
(en)
*
|
2017-08-30 |
2020-03-19 |
Phanes Therapeutics, Inc. |
Anti-LAG-3 antibodies and uses thereof
|
|
WO2019055579A1
(en)
|
2017-09-12 |
2019-03-21 |
Tolero Pharmaceuticals, Inc. |
TREATMENT REGIME FOR CANCERS THAT ARE INSENSITIVE TO BCL-2 INHIBITORS USING THE MCL-1 ALVOCIDIB INHIBITOR
|
|
US20210040205A1
(en)
|
2017-10-25 |
2021-02-11 |
Novartis Ag |
Antibodies targeting cd32b and methods of use thereof
|
|
CN112272563A
(zh)
*
|
2017-11-08 |
2021-01-26 |
Xencor股份有限公司 |
使用新颖抗pd-1序列的双特异性和单特异性抗体
|
|
US10981992B2
(en)
|
2017-11-08 |
2021-04-20 |
Xencor, Inc. |
Bispecific immunomodulatory antibodies that bind costimulatory and checkpoint receptors
|
|
MX2020004756A
(es)
|
2017-11-16 |
2020-08-20 |
Novartis Ag |
Terapias de combinacion.
|
|
US11111297B2
(en)
|
2017-11-17 |
2021-09-07 |
Merck Sharp & Dohme Corp. |
Antibodies specific for immunoglobulin-like transcript 3 (ILT3) and uses thereof
|
|
MX2020005651A
(es)
|
2017-11-30 |
2020-10-28 |
Novartis Ag |
Receptor de antigeno quimerico dirigido a bcma y usos del mismo.
|
|
CN111741976B
(zh)
|
2017-12-19 |
2024-09-17 |
英沃克斯制药有限公司 |
包括pd-l1抗原结合位点的fc结合片段
|
|
MX2020006322A
(es)
|
2017-12-19 |
2020-09-18 |
Xencor Inc |
Proteinas de fusion il-2 fc modificadas.
|
|
EP3714901A4
(en)
*
|
2017-12-22 |
2022-03-02 |
Jiangsu Hengrui Medicine Co., Ltd. |
ANTI-LAG-3 ANTIBODY PHARMACEUTICAL COMPOSITION AND USE THEREOF
|
|
CN109970856B
(zh)
|
2017-12-27 |
2022-08-23 |
信达生物制药(苏州)有限公司 |
抗lag-3抗体及其用途
|
|
WO2019129136A1
(zh)
|
2017-12-27 |
2019-07-04 |
信达生物制药(苏州)有限公司 |
抗pd-l1抗体及其用途
|
|
CN109970857B
(zh)
|
2017-12-27 |
2022-09-30 |
信达生物制药(苏州)有限公司 |
抗pd-l1抗体及其用途
|
|
WO2019129137A1
(zh)
|
2017-12-27 |
2019-07-04 |
信达生物制药(苏州)有限公司 |
抗lag-3抗体及其用途
|
|
EP3737408A1
(en)
|
2018-01-08 |
2020-11-18 |
Novartis AG |
Immune-enhancing rnas for combination with chimeric antigen receptor therapy
|
|
WO2019141092A1
(zh)
|
2018-01-18 |
2019-07-25 |
四川科伦博泰生物医药股份有限公司 |
抗lag-3抗体及其用途
|
|
CN108085393B
(zh)
*
|
2018-01-31 |
2020-06-02 |
青岛泱深生物医药有限公司 |
肾透明细胞癌相关生物标志物及其应用
|
|
EP3746116A1
(en)
|
2018-01-31 |
2020-12-09 |
Novartis AG |
Combination therapy using a chimeric antigen receptor
|
|
WO2019148410A1
(en)
|
2018-02-01 |
2019-08-08 |
Merck Sharp & Dohme Corp. |
Anti-pd-1 antibodies
|
|
WO2019148412A1
(en)
|
2018-02-01 |
2019-08-08 |
Merck Sharp & Dohme Corp. |
Anti-pd-1/lag3 bispecific antibodies
|
|
US20210363243A1
(en)
*
|
2018-02-01 |
2021-11-25 |
Merck Sharp & Dohme Corp. |
Methods for treating cancer or infection using a combination of an anti-pd-1 antibody, an anti-lag3 antibody, and an anti-tigit antibody
|
|
US11884733B2
(en)
|
2018-02-08 |
2024-01-30 |
Dragonfly Therapeutics, Inc. |
Antibody variable domains targeting the NKG2D receptor
|
|
CA3090236A1
(en)
|
2018-02-08 |
2019-08-15 |
Dragonfly Therapeutics, Inc. |
Combination therapy of cancer involving multi-specific binding proteins that activate natural killer cells
|
|
EP3752203A1
(en)
|
2018-02-13 |
2020-12-23 |
Novartis AG |
Chimeric antigen receptor therapy in combination with il-15r and il15
|
|
GB201802573D0
(en)
|
2018-02-16 |
2018-04-04 |
Crescendo Biologics Ltd |
Therapeutic molecules that bind to LAG3
|
|
KR102832460B1
(ko)
|
2018-02-20 |
2025-07-11 |
드래곤플라이 쎄라퓨틱스, 인크. |
Cd33, nkg2d, 및 cd16에 결합하는 다중-특이적 결합 단백질, 및 이의 사용 방법
|
|
US11661452B2
(en)
|
2018-03-20 |
2023-05-30 |
WuXi Biologics Ireland Limited |
Anti-lag-3 antibody polypeptide
|
|
CN110305215B
(zh)
*
|
2018-03-20 |
2023-11-03 |
基石药业 |
新型抗lag-3抗体多肽
|
|
JP7611700B2
(ja)
|
2018-03-27 |
2025-01-10 |
ブリストル－マイヤーズ スクイブ カンパニー |
紫外線シグナルを使用した力価のリアルタイムモニタリング
|
|
TW202003567A
(zh)
|
2018-03-30 |
2020-01-16 |
大陸商南京傳奇生物科技有限公司 |
針對lag-3之單一結構域抗體及其用途
|
|
JP7104458B2
(ja)
|
2018-04-02 |
2022-07-21 |
上海博威生物医薬有限公司 |
リンパ球活性化遺伝子－３（ｌａｇ－３）結合抗体およびその使用
|
|
US20220025037A1
(en)
*
|
2018-04-03 |
2022-01-27 |
Dragonfly Therapeutics, Inc. |
Antibody variable domains targeting dll3, and use thereof
|
|
CN112469477A
(zh)
|
2018-04-04 |
2021-03-09 |
Xencor股份有限公司 |
与成纤维细胞活化蛋白结合的异源二聚体抗体
|
|
US20210147547A1
(en)
|
2018-04-13 |
2021-05-20 |
Novartis Ag |
Dosage Regimens For Anti-Pd-L1 Antibodies And Uses Thereof
|
|
AU2019256539A1
(en)
|
2018-04-18 |
2020-11-26 |
Xencor, Inc. |
PD-1 targeted heterodimeric fusion proteins containing IL-15/IL-15Ra Fc-fusion proteins and PD-1 antigen binding domains and uses thereof
|
|
CA3097741A1
(en)
|
2018-04-18 |
2019-10-24 |
Xencor, Inc. |
Tim-3 targeted heterodimeric fusion proteins containing il-15/il-15ra fc-fusion proteins and tim-3 antigen binding domains
|
|
AU2019263850A1
(en)
|
2018-05-03 |
2020-11-19 |
Shanghai Epimab Biotherapeutics Co., Ltd. |
High affinity antibodies to PD-1 and LAG-3 and bispecific binding proteins made therefrom
|
|
AR126019A1
(es)
|
2018-05-30 |
2023-09-06 |
Novartis Ag |
Anticuerpos frente a entpd2, terapias de combinación y métodos de uso de los anticuerpos y las terapias de combinación
|
|
WO2019232244A2
(en)
|
2018-05-31 |
2019-12-05 |
Novartis Ag |
Antibody molecules to cd73 and uses thereof
|
|
UY38251A
(es)
|
2018-06-01 |
2019-12-31 |
Novartis Ag |
Moléculas de unión contra bcma y usos de las mismas
|
|
AR116109A1
(es)
|
2018-07-10 |
2021-03-31 |
Novartis Ag |
Derivados de 3-(5-amino-1-oxoisoindolin-2-il)piperidina-2,6-diona y usos de los mismos
|
|
KR102873348B1
(ko)
|
2018-07-10 |
2025-10-20 |
노파르티스 아게 |
3-(5-하이드록시-1-옥소이소인돌린-2-일)피페리딘-2,6-디온 유도체 및 ikaros 패밀리 아연 핑거 2(ikzf2)-의존성 질환의 치료에 있어서의 이의 용도
|
|
GB201811450D0
(en)
|
2018-07-12 |
2018-08-29 |
F Star Delta Ltd |
Mesothelin and CD137 binding molecules
|
|
AU2019301206B2
(en)
|
2018-07-12 |
2025-10-30 |
Invox Pharma Limited |
Antibody molecules that bind CD137 and OX40
|
|
GB201811410D0
(en)
|
2018-07-12 |
2018-08-29 |
F Star Beta Ltd |
OX40 Binding molecules
|
|
GB201811404D0
(en)
|
2018-07-12 |
2018-08-29 |
F Star Beta Ltd |
Anti-CD137 Antibodies
|
|
GB201811403D0
(en)
|
2018-07-12 |
2018-08-29 |
F Star Beta Ltd |
Antibody molecules
|
|
GB201811408D0
(en)
|
2018-07-12 |
2018-08-29 |
F Star Beta Ltd |
CD137 Binding Molecules
|
|
ES3006183T3
(en)
|
2018-07-12 |
2025-03-17 |
Invox Pharma Ltd |
Antibody molecules that bind pd-l1 and cd137
|
|
GB201811415D0
(en)
|
2018-07-12 |
2018-08-29 |
F Star Beta Ltd |
Anti-Mesothelin Anti bodies
|
|
WO2020021465A1
(en)
|
2018-07-25 |
2020-01-30 |
Advanced Accelerator Applications (Italy) S.R.L. |
Method of treatment of neuroendocrine tumors
|
|
US20210238287A1
(en)
|
2018-07-26 |
2021-08-05 |
Bristol-Myers Squibb Company |
LAG-3 Combination Therapy for the Treatment of Cancer
|
|
EA202091888A1
(ru)
|
2018-08-08 |
2020-10-23 |
Драгонфлай Терапьютикс, Инк. |
Вариабельные домены антител, нацеленные на рецептор nkg2d
|
|
AU2019318083A1
(en)
|
2018-08-08 |
2021-02-25 |
Dragonfly Therapeutics, Inc. |
Multi-specific binding proteins that bind BCMA, NKG2D and CD16, and methods of use
|
|
MA53284A
(fr)
|
2018-08-08 |
2022-01-26 |
Dragonfly Therapeutics Inc |
Protéines de liaison à nkg2d, à cd16 et à un antigène associé à une tumeur
|
|
US12173070B2
(en)
*
|
2018-08-21 |
2024-12-24 |
Abl Bio Inc. |
Anti-PD-L1/anti-LAG3 bispecific antibodies and uses thereof
|
|
EP3849606A4
(en)
*
|
2018-09-13 |
2022-06-29 |
Merck Sharp & Dohme Corp. |
Combination of pd-1 antagonist and lag3 antagonist for treating non-microsatellite instablity-high/proficient mismatch repair colorectal cancer
|
|
WO2020072821A2
(en)
|
2018-10-03 |
2020-04-09 |
Xencor, Inc. |
Il-12 heterodimeric fc-fusion proteins
|
|
EP4445958B1
(en)
|
2018-10-19 |
2025-09-24 |
Bristol-Myers Squibb Company |
Combination therapy for melanoma
|
|
WO2020089811A1
(en)
|
2018-10-31 |
2020-05-07 |
Novartis Ag |
Dc-sign antibody drug conjugates
|
|
WO2020096917A1
(en)
*
|
2018-11-05 |
2020-05-14 |
Merck Sharp & Dohme Corp. |
Dosing regimen of anti-lag3 antibody and combination therapy with anti-pd-1 antibody for treating cancer
|
|
AU2019377456A1
(en)
*
|
2018-11-07 |
2021-05-27 |
Merck Sharp & Dohme Llc |
Co-formulations of anti-lag3 antibodies and anti-pd-1 antibodies
|
|
EP3890749B1
(en)
|
2018-12-04 |
2025-10-29 |
Sumitomo Pharma America, Inc. |
Cdk9 inhibitors and polymorphs thereof for use as agents for treatment of cancer
|
|
WO2020128972A1
(en)
|
2018-12-20 |
2020-06-25 |
Novartis Ag |
Dosing regimen and pharmaceutical combination comprising 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives
|
|
PH12021551419A1
(en)
|
2018-12-21 |
2022-05-02 |
Onxeo |
New conjugated nucleic acid molecules and their uses
|
|
WO2020128637A1
(en)
|
2018-12-21 |
2020-06-25 |
Novartis Ag |
Use of il-1 binding antibodies in the treatment of a msi-h cancer
|
|
AU2019409139A1
(en)
|
2018-12-21 |
2021-06-03 |
Novartis Ag |
Use of IL-1β binding antibodies
|
|
EP3897613A1
(en)
|
2018-12-21 |
2021-10-27 |
Novartis AG |
Use of il-1beta binding antibodies
|
|
US20200369762A1
(en)
|
2018-12-21 |
2020-11-26 |
Novartis Ag |
Use of il-1beta binding antibodies
|
|
EP3918323A4
(en)
|
2019-01-30 |
2022-12-28 |
TrueBinding, Inc. |
ANTI-GAL3 ANTIBODIES AND USES THEREOF
|
|
JP7662528B2
(ja)
|
2019-02-12 |
2025-04-15 |
スミトモ ファーマ アメリカ， インコーポレイテッド |
複素環式タンパク質キナーゼ阻害剤を含む製剤
|
|
AU2020222346B2
(en)
|
2019-02-15 |
2021-12-09 |
Novartis Ag |
Substituted 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof
|
|
ES3032659T3
(en)
|
2019-02-15 |
2025-07-23 |
Novartis Ag |
3-(1-oxo-5-(piperidin-4-yl)isoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof
|
|
US20220135619A1
(en)
|
2019-02-24 |
2022-05-05 |
Bristol-Myers Squibb Company |
Methods of isolating a protein
|
|
EP3930850A1
(en)
|
2019-03-01 |
2022-01-05 |
Xencor, Inc. |
Heterodimeric antibodies that bind enpp3 and cd3
|
|
WO2020191326A1
(en)
|
2019-03-20 |
2020-09-24 |
Sumitomo Dainippon Pharma Oncology, Inc. |
Treatment of acute myeloid leukemia (aml) with venetoclax failure
|
|
JP7547360B2
(ja)
|
2019-03-22 |
2024-09-09 |
スミトモ ファーマ オンコロジー， インコーポレイテッド |
Ｐｋｍ２モジュレーターを含む組成物およびそれを使用する処置の方法
|
|
EP3947640A4
(en)
|
2019-04-02 |
2022-12-14 |
The Brigham & Women's Hospital, Inc. |
PROCEDURE FOR DETERMINING THE PROGRESSION OF PRIMARY MELANOMA
|
|
WO2020216383A1
(en)
*
|
2019-04-26 |
2020-10-29 |
Single Cell Technology, Inc. |
Anti-lag-3 antibodies
|
|
WO2020236668A1
(en)
*
|
2019-05-17 |
2020-11-26 |
Gb006, Inc. |
Leukadherin-1 alone or in combination for use in the treatment of cancer
|
|
WO2020237050A1
(en)
|
2019-05-22 |
2020-11-26 |
Leidos, Inc. |
Lag3 binding peptides
|
|
EP3973274A1
(en)
|
2019-05-23 |
2022-03-30 |
Bristol-Myers Squibb Company |
Methods of monitoring cell culture media
|
|
WO2020243570A1
(en)
|
2019-05-30 |
2020-12-03 |
Bristol-Myers Squibb Company |
Cell localization signature and combination therapy
|
|
JP2022534982A
(ja)
|
2019-05-30 |
2022-08-04 |
ブリストル－マイヤーズ スクイブ カンパニー |
細胞局在化シグネチャーおよびその使用
|
|
US20220363760A1
(en)
|
2019-05-30 |
2022-11-17 |
Bristol-Myers Squibb Company |
Multi-tumor gene signature for suitability to immuno-oncology therapy
|
|
KR20220028075A
(ko)
|
2019-07-03 |
2022-03-08 |
스미토모 다이니폰 파마 온콜로지, 인크. |
티로신 키나제 비-수용체 1 (tnk1) 억제제 및 그의 용도
|
|
KR20220035038A
(ko)
*
|
2019-07-17 |
2022-03-21 |
녹소팜 리미티드 |
이소플라본 화합물을 사용하는 면역종양학 요법
|
|
EP4003523A4
(en)
*
|
2019-07-30 |
2023-09-06 |
Merck Sharp & Dohme LLC |
ANTI-PD-1/LAG3/TIGIT TRISPECIFIC ANTIBODIES AND ANTI-PD-1/LAG3 BISPECIFIC ANTIBODIES
|
|
WO2021024020A1
(en)
|
2019-08-06 |
2021-02-11 |
Astellas Pharma Inc. |
Combination therapy involving antibodies against claudin 18.2 and immune checkpoint inhibitors for treatment of cancer
|
|
WO2021053559A1
(en)
|
2019-09-18 |
2021-03-25 |
Novartis Ag |
Entpd2 antibodies, combination therapies, and methods of using the antibodies and combination therapies
|
|
BR112022004316A2
(pt)
|
2019-09-22 |
2022-06-21 |
Bristol Myers Squibb Co |
Caracterização espacial quantitativa para terapia de antagonista lag-3
|
|
WO2021079188A1
(en)
|
2019-10-21 |
2021-04-29 |
Novartis Ag |
Combination therapies with venetoclax and tim-3 inhibitors
|
|
EP4048285A1
(en)
|
2019-10-21 |
2022-08-31 |
Novartis AG |
Tim-3 inhibitors and uses thereof
|
|
WO2021092220A1
(en)
|
2019-11-06 |
2021-05-14 |
Bristol-Myers Squibb Company |
Methods of identifying a subject with a tumor suitable for a checkpoint inhibitor therapy
|
|
WO2021092221A1
(en)
|
2019-11-06 |
2021-05-14 |
Bristol-Myers Squibb Company |
Methods of identifying a subject with a tumor suitable for a checkpoint inhibitor therapy
|
|
MX2022005474A
(es)
|
2019-11-08 |
2022-06-02 |
Bristol Myers Squibb Co |
Tratamiento de melanoma con antagonistas del gen 3 de activacion de linfocitos (lag-3).
|
|
MX2022005034A
(es)
*
|
2019-11-11 |
2022-05-16 |
Cstone Pharmaceuticals Suzhou Co Ltd |
Combinacion farmaceutica y uso de la misma.
|
|
WO2021126967A1
(en)
*
|
2019-12-20 |
2021-06-24 |
Merck Sharp & Dohme Corp. |
Lag3 antagonist cell based potency assay
|
|
BR112022011902A2
(pt)
|
2019-12-20 |
2022-09-06 |
Novartis Ag |
Terapias de combinação
|
|
WO2021144657A1
(en)
|
2020-01-17 |
2021-07-22 |
Novartis Ag |
Combination comprising a tim-3 inhibitor and a hypomethylating agent for use in treating myelodysplastic syndrome or chronic myelomonocytic leukemia
|
|
CA3165211A1
(en)
*
|
2020-01-21 |
2021-07-29 |
Ge Song |
Anti-lag3 monoclonal antibody, and preparation method therefor and use thereof
|
|
CA3165528A1
(en)
*
|
2020-01-29 |
2021-08-05 |
Colette M. Cutler |
Methods of separating host cell lipases from an anti-lag3 antibody production
|
|
EP4100426A1
(en)
|
2020-02-06 |
2022-12-14 |
Bristol-Myers Squibb Company |
Il-10 and uses thereof
|
|
KR102245082B1
(ko)
*
|
2020-02-14 |
2021-04-26 |
단국대학교 천안캠퍼스 산학협력단 |
치주인대전구세포 표면에 특이적으로 결합하는 두 가지 IgG 타입 단일클론항체 LG43, LG73 및 그의 용도
|
|
AU2021247415A1
(en)
|
2020-03-30 |
2022-09-29 |
Noxopharm Limited |
Methods for the treatment of inflammation associated with infection
|
|
WO2021216620A1
(en)
*
|
2020-04-21 |
2021-10-28 |
Board Of Regents, The University Of Texas System |
Methods for treating bladder cancer
|
|
CA3176661A1
(en)
*
|
2020-04-24 |
2021-10-28 |
Memorial Sloan-Kettering Cancer Center |
Targeted therapy for the treatment & prevention of life-threatening complications of infection
|
|
IL297922A
(en)
|
2020-05-06 |
2023-01-01 |
Dragonfly Therapeutics Inc |
Proteins binding nkg2d, cd16 and clec12a
|
|
US11919956B2
(en)
|
2020-05-14 |
2024-03-05 |
Xencor, Inc. |
Heterodimeric antibodies that bind prostate specific membrane antigen (PSMA) and CD3
|
|
CA3185040A1
(en)
|
2020-05-26 |
2021-12-02 |
Truebinding, Inc. |
Methods of treating inflammatory diseases by blocking galectin-3
|
|
WO2021247789A1
(en)
|
2020-06-04 |
2021-12-09 |
Leidos, Inc. |
Immunomodulatory compounds
|
|
CN114605544B
(zh)
*
|
2020-06-05 |
2023-08-01 |
北京天广实生物技术股份有限公司 |
Lag3抗体及其用途
|
|
AR122644A1
(es)
|
2020-06-19 |
2022-09-28 |
Onxeo |
Nuevas moléculas de ácido nucleico conjugado y sus usos
|
|
CN115916199A
(zh)
|
2020-06-23 |
2023-04-04 |
诺华股份有限公司 |
包含3-(1-氧代异吲哚啉-2-基)哌啶-2,6-二酮衍生物的给药方案
|
|
MX2023000197A
(es)
|
2020-07-07 |
2023-02-22 |
BioNTech SE |
Arn terapeutico para el cancer positivo para vph.
|
|
JP2023536466A
(ja)
|
2020-07-31 |
2023-08-25 |
レイドス， インコーポレイテッド |
Ｌａｇ３結合ペプチド
|
|
CN116134027B
(zh)
|
2020-08-03 |
2025-01-24 |
诺华股份有限公司 |
杂芳基取代的3-(1-氧代异吲哚啉-2-基)哌啶-2,6-二酮衍生物及其用途
|
|
US11919958B2
(en)
|
2020-08-19 |
2024-03-05 |
Xencor, Inc. |
Anti-CD28 compositions
|
|
MX2023002332A
(es)
|
2020-08-28 |
2023-03-21 |
Bristol Myers Squibb Co |
Terapia con antagonistas del gen 3 de activacion de linfocitos (lag-3) para carcinoma hepatocelular.
|
|
WO2022047412A1
(en)
|
2020-08-31 |
2022-03-03 |
Bristol-Myers Squibb Company |
Cell localization signature and immunotherapy
|
|
EP4204021A1
(en)
|
2020-08-31 |
2023-07-05 |
Advanced Accelerator Applications International S.A. |
Method of treating psma-expressing cancers
|
|
EP4204020A1
(en)
|
2020-08-31 |
2023-07-05 |
Advanced Accelerator Applications International S.A. |
Method of treating psma-expressing cancers
|
|
JP2023544410A
(ja)
|
2020-10-05 |
2023-10-23 |
ブリストル－マイヤーズ スクイブ カンパニー |
タンパク質を濃縮するための方法
|
|
AU2021364837A1
(en)
|
2020-10-23 |
2023-05-25 |
Bristol-Myers Squibb Company |
Lag-3 antagonist therapy for lung cancer
|
|
EP4240491A1
(en)
|
2020-11-06 |
2023-09-13 |
Novartis AG |
Cd19 binding molecules and uses thereof
|
|
WO2022109987A1
(en)
*
|
2020-11-27 |
2022-06-02 |
Shanghai Benemae Pharmaceutical Corporation |
Novel anti-lag3 antibodies and methods of making and using the same
|
|
JP2024508207A
(ja)
|
2020-12-02 |
2024-02-26 |
ブイアイビー ブイゼットダブリュ |
がんに対する組み合わせ治療におけるｌｔｂｒアゴニスト
|
|
WO2022120179A1
(en)
|
2020-12-03 |
2022-06-09 |
Bristol-Myers Squibb Company |
Multi-tumor gene signatures and uses thereof
|
|
CN115819585B
(zh)
*
|
2020-12-10 |
2023-06-02 |
北京东方百泰生物科技股份有限公司 |
一种抗lag-3的单克隆抗体、其抗原结合片段及其应用
|
|
TW202237119A
(zh)
|
2020-12-10 |
2022-10-01 |
美商住友製藥腫瘤公司 |
Ａｌｋ﹘５抑制劑和彼之用途
|
|
WO2022135667A1
(en)
|
2020-12-21 |
2022-06-30 |
BioNTech SE |
Therapeutic rna for treating cancer
|
|
WO2022135666A1
(en)
|
2020-12-21 |
2022-06-30 |
BioNTech SE |
Treatment schedule for cytokine proteins
|
|
TW202245808A
(zh)
|
2020-12-21 |
2022-12-01 |
德商拜恩迪克公司 |
用於治療癌症之治療性ｒｎａ
|
|
WO2022146947A1
(en)
|
2020-12-28 |
2022-07-07 |
Bristol-Myers Squibb Company |
Antibody compositions and methods of use thereof
|
|
CA3196999A1
(en)
|
2020-12-28 |
2022-07-07 |
Masano HUANG |
Methods of treating tumors
|
|
AU2022212123A1
(en)
|
2021-01-29 |
2023-09-07 |
Board Of Regents, The University Of Texas System |
Methods of treating cancer with kinase inhibitors
|
|
CN117222663A
(zh)
|
2021-03-03 |
2023-12-12 |
蜻蜓疗法股份有限公司 |
使用结合nkg2d、cd16和肿瘤相关抗原的多特异性结合蛋白治疗癌症的方法
|
|
US11845791B2
(en)
*
|
2021-03-08 |
2023-12-19 |
Medimmune, Llc |
Antibodies directed against GDF-15
|
|
CA3212665A1
(en)
|
2021-03-09 |
2022-09-15 |
Xencor, Inc. |
Heterodimeric antibodies that bind cd3 and cldn6
|
|
JP2024509274A
(ja)
|
2021-03-10 |
2024-02-29 |
ゼンコア インコーポレイテッド |
Ｃｄ３及びｇｐｃ３に結合するヘテロ二量体抗体
|
|
AU2022246593A1
(en)
|
2021-03-29 |
2023-10-12 |
Juno Therapeutics, Inc. |
Methods for dosing and treatment with a combination of a checkpoint inhibitor therapy and a car t cell therapy
|
|
TW202304979A
(zh)
|
2021-04-07 |
2023-02-01 |
瑞士商諾華公司 |
抗ＴＧＦβ抗體及其他治療劑用於治療增殖性疾病之用途
|
|
EP4319755A4
(en)
|
2021-04-08 |
2025-03-26 |
Board of Regents, The University of Texas System |
Compounds and methods for theranostic targeting of parp activity
|
|
CA3213079A1
(en)
|
2021-04-13 |
2022-10-20 |
Kristin Lynne ANDREWS |
Amino-substituted heterocycles for treating cancers with egfr mutations
|
|
US20240285740A1
(en)
|
2021-05-12 |
2024-08-29 |
Dana-Farber Cancer Institute, Inc. |
Compositions and methods for treating cancer
|
|
AR125874A1
(es)
|
2021-05-18 |
2023-08-23 |
Novartis Ag |
Terapias de combinación
|
|
CN115403670A
(zh)
|
2021-05-26 |
2022-11-29 |
安徽瀚海博兴生物技术有限公司 |
抗cd40抗体及其用途
|
|
JP2024525758A
(ja)
|
2021-07-13 |
2024-07-12 |
ビオンテック・ソシエタス・エウロパエア |
がんのための併用療法におけるｃｄ４０およびｃｄ１３７に対する多重特異性結合剤
|
|
CN115611983A
(zh)
|
2021-07-14 |
2023-01-17 |
三优生物医药(上海)有限公司 |
Cldn18.2结合分子及其用途
|
|
JP2024534080A
(ja)
*
|
2021-08-17 |
2024-09-18 |
ウェアウルフ セラピューティクス， インコーポレイテッド |
誘導性ｉｌ－２及びｐｄ－１／ｐｄ－ｌ１の併用療法
|
|
CA3233205A1
(en)
*
|
2021-09-29 |
2023-04-06 |
Yu Xia |
Anti-lag3 antibody, pharmaceutical composition and use
|
|
TW202333802A
(zh)
|
2021-10-11 |
2023-09-01 |
德商拜恩迪克公司 |
用於肺癌之治療性rna(二)
|
|
CN118176214A
(zh)
|
2021-10-29 |
2024-06-11 |
百时美施贵宝公司 |
血液癌症的lag-3拮抗剂疗法
|
|
US20250313625A1
(en)
*
|
2021-11-01 |
2025-10-09 |
Elpiscience (Suzhou) Biopharma, Ltd. |
Novel anti-lag3 antibodies
|
|
IL313439A
(en)
|
2021-12-16 |
2024-08-01 |
Valerio Therapeutics |
New conjugated nucleic acid molecules and their uses
|
|
JP2025503962A
(ja)
|
2022-01-26 |
2025-02-06 |
ブリストル－マイヤーズ スクイブ カンパニー |
肝細胞がんのための併用療法
|
|
WO2023161350A1
(en)
|
2022-02-24 |
2023-08-31 |
Io Biotech Aps |
Nucleotide delivery of cancer therapy
|
|
JP2025507694A
(ja)
|
2022-02-25 |
2025-03-21 |
ブリストル－マイヤーズ スクイブ カンパニー |
結腸直腸癌に対する組み合わせ療法
|
|
WO2023168404A1
(en)
|
2022-03-04 |
2023-09-07 |
Bristol-Myers Squibb Company |
Methods of treating a tumor
|
|
EP4490191A1
(en)
|
2022-03-08 |
2025-01-15 |
Alentis Therapeutics AG |
Use of anti-claudin-1 antibodies to increase t cell availability
|
|
KR20240156411A
(ko)
|
2022-03-09 |
2024-10-29 |
브리스톨-마이어스 스큅 컴퍼니 |
치료 단백질의 일시적 발현
|
|
JP2025509832A
(ja)
|
2022-03-15 |
2025-04-11 |
コンピュジェン リミテッド |
Ｉｌ－１８ｂｐアンタゴニスト抗体、並びに癌の治療での単剤療法及び併用療法におけるそれらの使用
|
|
US20250206775A1
(en)
|
2022-03-18 |
2025-06-26 |
Bristol-Myers Squibb Company |
Methods of isolating polypeptides
|
|
CN114634574B
(zh)
*
|
2022-04-18 |
2022-12-20 |
先进生物(苏州)有限公司 |
抗B7H6的scFv抗体、其编码基因及其应用
|
|
WO2023214325A1
(en)
|
2022-05-05 |
2023-11-09 |
Novartis Ag |
Pyrazolopyrimidine derivatives and uses thereof as tet2 inhibitors
|
|
IL317319A
(en)
|
2022-06-02 |
2025-01-01 |
Bristol Myers Squibb Co |
Antibody compounds and methods of using them
|
|
WO2024102603A1
(en)
*
|
2022-11-07 |
2024-05-16 |
Merck Sharp & Dohme Llc |
Bisecting-glycan bridged conjugation for producing glycoprotein conjugates
|
|
TW202440157A
(zh)
|
2022-12-01 |
2024-10-16 |
英商梅迪繆思有限公司 |
用於治療癌症的組合療法
|
|
AU2023393653A1
(en)
|
2022-12-14 |
2025-05-22 |
Astellas Pharma Europe Bv |
Combination therapy involving bispecific binding agents binding to cldn18.2 and cd3 and immune checkpoint inhibitors
|
|
CN120731228A
(zh)
|
2022-12-21 |
2025-09-30 |
百时美施贵宝公司 |
肺癌的组合疗法
|
|
EP4658687A1
(en)
|
2023-01-31 |
2025-12-10 |
University of Rochester |
Immune checkpoint blockade therapy for treating staphylococcus aureus infections
|
|
US20240299601A1
(en)
|
2023-02-17 |
2024-09-12 |
Regeneron Pharmaceuticals, Inc. |
Radiolabeled anti-lag3 antibodies for immuno-pet imaging
|
|
WO2024175699A1
(en)
|
2023-02-23 |
2024-08-29 |
Imcheck Therapeutics |
Combination of btn3a activating antibody and immune checkpoint inhibitors
|
|
CN120835901A
(zh)
|
2023-03-13 |
2025-10-24 |
豪夫迈·罗氏有限公司 |
采用pd1-lag3双特异性抗体和hla-g t细胞双特异性抗体的组合疗法
|
|
WO2024196952A1
(en)
|
2023-03-20 |
2024-09-26 |
Bristol-Myers Squibb Company |
Tumor subtype assessment for cancer therapy
|
|
TW202515608A
(zh)
|
2023-06-26 |
2025-04-16 |
以色列商坎布根有限公司 |
Ｉｌ—１８ｂｐ拮抗抗體及其於癌症治療之單一療法及組合療法的用途
|
|
WO2025038763A1
(en)
|
2023-08-15 |
2025-02-20 |
Bristol-Myers Squibb Company |
Ceramic hydroxyapatite chromatography flow through method
|
|
WO2025054110A1
(en)
*
|
2023-09-07 |
2025-03-13 |
Merck Sharp & Dohme Llc |
Combination therapy of a pd-1 antagonist and lag3 antagonist for treating patients with cancer before and/or after surgery
|
|
WO2025068461A1
(en)
|
2023-09-29 |
2025-04-03 |
Negio Therapeutics |
Guanfacine derivatives and their use in treating cancer
|
|
WO2025068452A1
(en)
|
2023-09-29 |
2025-04-03 |
Negio Therapeutics |
Guanfacine derivatives and their use in treating cancer
|
|
TW202535926A
(zh)
|
2023-10-30 |
2025-09-16 |
美商再生元醫藥公司 |
穩定抗體配製物
|
|
WO2025120867A1
(en)
|
2023-12-08 |
2025-06-12 |
Astellas Pharma Inc. |
Combination therapy involving bispecific binding agents binding to cldn18.2 and cd3 and anti-vegfr2 antibodies
|
|
WO2025121445A1
(en)
|
2023-12-08 |
2025-06-12 |
Astellas Pharma Inc. |
Combination therapy involving bispecific binding agents binding to cldn18.2 and cd3 and agents stabilizing or increasing expression of cldn18.2
|
|
WO2025120866A1
(en)
|
2023-12-08 |
2025-06-12 |
Astellas Pharma Inc. |
Combination therapy involving bispecific binding agents binding to cldn18.2 and cd3 and agents stabilizing or increasing expression of cldn18.2
|
|
WO2025132831A1
(en)
|
2023-12-19 |
2025-06-26 |
Universite D'aix-Marseille |
N-heteroaryl derivatives and uses thereof for treating cancer
|
|
US20250215087A1
(en)
|
2023-12-29 |
2025-07-03 |
Bristol-Myers Squibb Company |
Combination therapy of kras inhibitor and treg depleting agent
|
|
US20250361320A1
(en)
|
2024-02-27 |
2025-11-27 |
Bristol-Myers Squibb Company |
Anti-ceacam5 antibodies and uses thereof
|
|
EP4658320A1
(en)
|
2024-02-27 |
2025-12-10 |
Bristol-Myers Squibb Company |
Anti-ceacam5 antibody drug conjugates
|
|
WO2025202213A1
(en)
|
2024-03-26 |
2025-10-02 |
Institut National de la Santé et de la Recherche Médicale |
Lipid nanoparticle loaded with antitumoral agent and functionnalized to target immosuppressive cells
|
|
WO2025226695A1
(en)
|
2024-04-23 |
2025-10-30 |
Regeneron Pharmaceuticals, Inc. |
Stable antibody formulation
|
|
WO2025245489A1
(en)
|
2024-05-24 |
2025-11-27 |
Bristol-Myers Squibb Company |
Treatment of tumors in subjects having fgl-1 positive samples
|
|
WO2025262250A1
(en)
|
2024-06-20 |
2025-12-26 |
Negio Therapeutics |
Guanfacine derivatives and their uses
|