JP2022507485A5 - - Google Patents

Info

Publication number
JP2022507485A5
JP2022507485A5 JP2021526459A JP2021526459A JP2022507485A5 JP 2022507485 A5 JP2022507485 A5 JP 2022507485A5 JP 2021526459 A JP2021526459 A JP 2021526459A JP 2021526459 A JP2021526459 A JP 2021526459A JP 2022507485 A5 JP2022507485 A5 JP 2022507485A5
Authority
JP
Japan
Prior art keywords
sequence
cdr2
cdr3
cdr1
protein according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2021526459A
Other languages
English (en)
Japanese (ja)
Other versions
JP7785284B2 (ja
JP2022507485A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2019/061884 external-priority patent/WO2020102777A1/en
Publication of JP2022507485A publication Critical patent/JP2022507485A/ja
Publication of JP2022507485A5 publication Critical patent/JP2022507485A5/ja
Priority to JP2025203085A priority Critical patent/JP2026053336A/ja
Application granted granted Critical
Publication of JP7785284B2 publication Critical patent/JP7785284B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2021526459A 2018-11-16 2019-11-15 Cd38抗体とicam1抗体およびそれらの使用 Active JP7785284B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2025203085A JP2026053336A (ja) 2018-11-16 2025-11-25 Cd38抗体とicam1抗体およびそれらの使用

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862768566P 2018-11-16 2018-11-16
US62/768,566 2018-11-16
PCT/US2019/061884 WO2020102777A1 (en) 2018-11-16 2019-11-15 Cd38 and icam1 antibodies and uses thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2025203085A Division JP2026053336A (ja) 2018-11-16 2025-11-25 Cd38抗体とicam1抗体およびそれらの使用

Publications (3)

Publication Number Publication Date
JP2022507485A JP2022507485A (ja) 2022-01-18
JP2022507485A5 true JP2022507485A5 (enExample) 2022-11-22
JP7785284B2 JP7785284B2 (ja) 2025-12-15

Family

ID=70731683

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2021526459A Active JP7785284B2 (ja) 2018-11-16 2019-11-15 Cd38抗体とicam1抗体およびそれらの使用
JP2025203085A Pending JP2026053336A (ja) 2018-11-16 2025-11-25 Cd38抗体とicam1抗体およびそれらの使用

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2025203085A Pending JP2026053336A (ja) 2018-11-16 2025-11-25 Cd38抗体とicam1抗体およびそれらの使用

Country Status (5)

Country Link
US (1) US12583932B2 (enExample)
EP (1) EP3883967A4 (enExample)
JP (2) JP7785284B2 (enExample)
CN (2) CN113302207B (enExample)
WO (1) WO2020102777A1 (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113302207B (zh) 2018-11-16 2025-05-13 维尔托索宾科公司 Cd38和icam1抗体及其用途
US20220411508A1 (en) * 2019-09-09 2022-12-29 The Regents Of The University Of California Compositions and methods for making and using multispecific antibodies
US20230312740A1 (en) * 2020-05-14 2023-10-05 Virtuoso Binco, Inc. Humanized cd38 and icam1 antibodies and uses thereof
WO2023034416A2 (en) * 2021-09-01 2023-03-09 Virtuoso Binco, Inc. Anti-icam1 antibodies and uses thereof
WO2023055376A1 (en) * 2021-09-30 2023-04-06 Virtuoso Binco, Inc. Multispecific antibodies for targeting cd47 and icam1 and methods of use thereof
KR102711074B1 (ko) * 2021-10-26 2024-10-04 재단법인 아산사회복지재단 암 생존자 유래 항체 및 이의 용도
WO2024207177A1 (en) * 2023-04-04 2024-10-10 Genequantum Healthcare (Suzhou) Co., Ltd. Antibody, linkers, payload, conjugates and applications thereof
CN117618446A (zh) * 2023-11-21 2024-03-01 西南大学 地塞米松在制备治疗结外鼻型nk/t细胞淋巴瘤转移的药物中的应用
WO2025149667A1 (en) 2024-01-12 2025-07-17 Pheon Therapeutics Ltd Antibody drug conjugates and uses thereof
US20250288611A1 (en) * 2024-03-04 2025-09-18 AffyImmune Therapeutics Inc. Icam-1 targeted car constructs and methods of treatment
CN118440185B (zh) * 2024-05-22 2024-11-19 宁夏大学 抗bhv-1的重组兔单克隆抗体及双抗体夹心elisa试剂和应用
KR20260025270A (ko) * 2024-08-12 2026-02-24 재단법인 아산사회복지재단 암 생존자 유래의 당쇄 특이적 항암 항체
CN119529093B (zh) * 2024-11-29 2026-03-06 武汉爱博泰克生物科技有限公司 一种抗人cd68单克隆抗体及其制备方法和应用

Family Cites Families (64)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5892644A (ja) 1981-11-26 1983-06-02 Taiho Yakuhin Kogyo Kk 新規なニトロ安息香酸アミド誘導体およびそれを含有する放射線増感剤
US4694778A (en) 1984-05-04 1987-09-22 Anicon, Inc. Chemical vapor deposition wafer boat
US4866132A (en) 1986-04-17 1989-09-12 The Research Foundation Of State University Of New York Novel radiopaque barium polymer complexes, compositions of matter and articles prepared therefrom
US5616584A (en) 1986-09-25 1997-04-01 Sri International 1,2,4-benzotriazine oxides as radiosensitizers and selective cytotoxic agents
US4921963A (en) 1987-04-13 1990-05-01 British Columbia Cancer Foundation Platinum complexes with one radiosensitizing ligand
JPH0819111B2 (ja) 1987-10-22 1996-02-28 ポーラ化成工業株式会社 2―ニトロイミダゾール誘導体及びこれを有効成分とする放射線増感剤
US5256334A (en) 1988-09-08 1993-10-26 The Research Foundation Of The State University Of New York Homogeneous radiopaque polymer-organobismuth composites
US5208020A (en) 1989-10-25 1993-05-04 Immunogen Inc. Cytotoxic agents comprising maytansinoids and their therapeutic use
US5637481A (en) * 1993-02-01 1997-06-10 Bristol-Myers Squibb Company Expression vectors encoding bispecific fusion proteins and methods of producing biologically active bispecific fusion proteins in a mammalian cell
EP0654993A1 (en) 1992-08-17 1995-05-31 Quadra Logic Technologies Inc. Method for destroying or inhibiting growth of unwanted cells or tissues
US5346981A (en) 1993-01-13 1994-09-13 Miles Inc. Radiopaque polyurethanes
US5599796A (en) 1993-12-02 1997-02-04 Emory University Treatment of urogenital cancer with boron neutron capture therapy
WO1996019487A1 (en) 1994-12-22 1996-06-27 Nissan Chemical Industries, Ltd. Organobismuth derivatives and process for producing the same
US5731168A (en) 1995-03-01 1998-03-24 Genentech, Inc. Method for making heteromultimeric polypeptides
US5700825A (en) 1995-03-31 1997-12-23 Florida State University Radiosensitizing diamines and their pharmaceutical preparations
GB9816575D0 (en) 1998-07-31 1998-09-30 Zeneca Ltd Novel compounds
GB9818731D0 (en) 1998-08-27 1998-10-21 Univ Portsmouth Compounds
GB9818730D0 (en) 1998-08-27 1998-10-21 Univ Portsmouth Collections of compounds
ES2260570T3 (es) 1998-08-27 2006-11-01 Spirogen Limited Pirrolobenziodiazepinas dimericas.
US6884869B2 (en) 2001-04-30 2005-04-26 Seattle Genetics, Inc. Pentapeptide compounds and uses related thereto
AU2002368077B2 (en) 2001-07-12 2010-03-04 Jefferson Foote Super humanized antibodies
US6716821B2 (en) 2001-12-21 2004-04-06 Immunogen Inc. Cytotoxic agents bearing a reactive polyethylene glycol moiety, cytotoxic conjugates comprising polyethylene glycol linking groups, and methods of making and using the same
US20040132101A1 (en) 2002-09-27 2004-07-08 Xencor Optimized Fc variants and methods for their generation
ES2369542T3 (es) 2002-07-31 2011-12-01 Seattle Genetics, Inc. Conjugados de auristatina y su uso para tratar cáncer, una enfermedad autoinmune o una enfermedad infecciosa.
US7276497B2 (en) 2003-05-20 2007-10-02 Immunogen Inc. Cytotoxic agents comprising new maytansinoids
GB0416511D0 (en) 2003-10-22 2004-08-25 Spirogen Ltd Pyrrolobenzodiazepines
ES2605443T3 (es) 2003-11-06 2017-03-14 Seattle Genetics, Inc. Conjugados de auristatina con anticuerpos anti-HER2 o anti-CD22 y su uso en terapia
WO2005062977A2 (en) * 2003-12-23 2005-07-14 The Regents Of The University Of California Prostate cancer specific internalizing human antibodies
EP1723152B1 (en) 2004-03-09 2015-02-11 Spirogen Sàrl Pyrrolobenzodiazepines
JP2008519863A (ja) 2004-11-12 2008-06-12 シアトル ジェネティクス インコーポレイティッド N末端にアミノ安息香酸単位を有するオーリスタチン
ES2338696T3 (es) 2005-04-21 2010-05-11 Spirogen Limited Pirrolobenzodiazepinas.
WO2007008848A2 (en) 2005-07-07 2007-01-18 Seattle Genetics, Inc. Monomethylvaline compounds having phenylalanine carboxy modifications at the c-terminus
DK1813614T3 (da) 2006-01-25 2012-01-23 Sanofi Sa Cytotoksiske midler, der omfatter nye tomaymycinderivater
US7750116B1 (en) 2006-02-18 2010-07-06 Seattle Genetics, Inc. Antibody drug conjugate metabolites
CN105837690A (zh) * 2006-06-12 2016-08-10 新兴产品开发西雅图有限公司 具有效应功能的单链多价结合蛋白
EP2148886B1 (en) 2007-05-10 2014-02-19 R & D Biopharmaceuticals Gmbh Tubulysine derivatives
PT2019104E (pt) 2007-07-19 2013-12-03 Sanofi Sa Agentes citotóxicos compreendendo novos derivados de tomaimicina e sua utilização terapêutica
US20090076249A1 (en) * 2007-09-19 2009-03-19 Michel De Weers Antibodies against CD38 for treatment of multiple myeloma
GB0813432D0 (en) 2008-07-22 2008-08-27 Spirogen Ltd Pyrrolobenzodiazepines
CA3014224C (en) 2009-02-05 2022-05-24 Immunogen, Inc. Condensed benzodiazepine-indoline derivatives and processes to prepare said derivatives
IT1394860B1 (it) 2009-07-22 2012-07-20 Kemotech S R L Composti farmaceutici
MX368648B (es) 2010-04-15 2019-10-09 Seattle Genetics Inc Pirrolobenzodiazepinas usadas para tratar enfermedades proliferativas.
CN103068405A (zh) 2010-04-15 2013-04-24 西雅图基因公司 靶向吡咯并苯并二氮杂卓结合物
JP2013531981A (ja) 2010-06-11 2013-08-15 アンチセンス・ファーマ・ゲーエムベーハー 選択的オリゴヌクレオチド修飾の方法
EP2409983A1 (en) 2010-07-19 2012-01-25 Leibniz-Institut für Pflanzenbiochemie (IPB) Tubulysin analogues
CN102372778B (zh) * 2010-08-19 2015-06-17 上海抗体药物国家工程研究中心有限公司 抗人vegf和opn双特异性抗体、其制备方法及用途
US9090629B2 (en) 2010-11-03 2015-07-28 Immunogen, Inc. Cytotoxic agents comprising new ansamitocin derivatives
WO2012177837A2 (en) 2011-06-21 2012-12-27 Immunogen, Inc. Novel maytansinoid derivatives with peptide linker and conjugates thereof
UA117901C2 (uk) 2011-07-06 2018-10-25 Ґенмаб Б.В. Спосіб посилення ефекторної функції вихідного поліпептиду, його варіанти та їх застосування
CA2850373C (en) 2011-10-14 2019-07-16 Seattle Genetics, Inc. Pyrrolobenzodiazepines and targeted conjugates
BR112014013526A8 (pt) 2011-12-05 2017-06-13 Igenica Biotherapeutics Inc conjugados de anticorpo-fármaco e compostos, composições e métodos relacionados
CN104640572B (zh) 2012-05-15 2018-04-27 索伦托医疗有限公司 药物偶联物,偶联方法,及其用途
SG10201609535TA (en) * 2012-06-05 2017-01-27 Regeneron Pharma Methods for making fully human bispecific antibodies using a common light chain
KR20210132742A (ko) 2012-12-21 2021-11-04 알트루바이오 인코퍼레이티드 친수성 자기-희생 링커 및 그것의 포합체
US9701759B2 (en) * 2013-01-14 2017-07-11 Xencor, Inc. Heterodimeric proteins
MX363787B (es) 2013-03-13 2019-04-03 Medimmune Ltd Pirrolobenzodiazepinas y conjugados de los mismos.
EP2777714A1 (en) 2013-03-15 2014-09-17 NBE-Therapeutics LLC Method of producing an immunoligand/payload conjugate by means of a sequence-specific transpeptidase enzyme
US20140363454A1 (en) 2013-06-06 2014-12-11 Igenica Biotherapeutics, Inc. Antibody-Drug Conjugates, Compositions and Methods of Use
WO2015038426A1 (en) 2013-09-13 2015-03-19 Asana Biosciences, Llc Self-immolative linkers containing mandelic acid derivatives, drug-ligand conjugates for targeted therapies and uses thereof
AU2014337317A1 (en) 2013-10-15 2016-09-15 Sorrento Therapeutics Inc. Drug-conjugates with a targeting molecule and two different drugs
EP4050026A1 (en) 2014-04-01 2022-08-31 Adimab, LLC Method of obtaining or identifying one or more common light chains for use in preparing a multispecific antibody
AU2016312259B2 (en) * 2015-08-26 2018-12-06 Bison Therapeutics Inc. Multispecific antibody platform and related methods
CN109310755A (zh) * 2016-02-02 2019-02-05 卡德门企业有限公司 Pd-l1和kdr的双特异性结合蛋白
CN113302207B (zh) 2018-11-16 2025-05-13 维尔托索宾科公司 Cd38和icam1抗体及其用途

Similar Documents

Publication Publication Date Title
JP2019122405A5 (enExample)
JP2018035138A5 (enExample)
JP2018183173A5 (enExample)
JP2021534096A5 (enExample)
JP2021508469A5 (enExample)
RU2019141289A (ru) АНТИ-SIRPα АНТИТЕЛА
JP2020517249A5 (enExample)
JP2022507487A5 (enExample)
JP2017149720A5 (enExample)
JP2016505556A5 (enExample)
JP2017535257A5 (enExample)
JP2017528476A5 (enExample)
JP2021533159A5 (enExample)
JP2018508188A5 (enExample)
JP2018517431A5 (enExample)
JP2020514277A5 (enExample)
JP2015533853A5 (enExample)
JP2015504421A5 (enExample)
RU2016137110A (ru) Антитела к компоненту комплемента с5
RU2014143784A (ru) Фармацевтическая композиция для лечения и/или предотвращения рака желчного пузыря
JP2013198490A5 (enExample)
JP2012532851A5 (enExample)
RU2012103212A (ru) Tlr3 связывающие агенты
JP2021098732A5 (enExample)
JP2021533796A5 (enExample)