|
US4399216A
(en)
|
1980-02-25 |
1983-08-16 |
The Trustees Of Columbia University |
Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials
|
|
US4634665A
(en)
|
1980-02-25 |
1987-01-06 |
The Trustees Of Columbia University In The City Of New York |
Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials
|
|
US5179017A
(en)
|
1980-02-25 |
1993-01-12 |
The Trustees Of Columbia University In The City Of New York |
Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials
|
|
US4475196A
(en)
|
1981-03-06 |
1984-10-02 |
Zor Clair G |
Instrument for locating faults in aircraft passenger reading light and attendant call control system
|
|
US4447233A
(en)
|
1981-04-10 |
1984-05-08 |
Parker-Hannifin Corporation |
Medication infusion pump
|
|
US4439196A
(en)
|
1982-03-18 |
1984-03-27 |
Merck & Co., Inc. |
Osmotic drug delivery system
|
|
US4522811A
(en)
|
1982-07-08 |
1985-06-11 |
Syntex (U.S.A.) Inc. |
Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides
|
|
US4447224A
(en)
|
1982-09-20 |
1984-05-08 |
Infusaid Corporation |
Variable flow implantable infusion apparatus
|
|
US4487603A
(en)
|
1982-11-26 |
1984-12-11 |
Cordis Corporation |
Implantable microinfusion pump system
|
|
US4816567A
(en)
|
1983-04-08 |
1989-03-28 |
Genentech, Inc. |
Recombinant immunoglobin preparations
|
|
US4486194A
(en)
|
1983-06-08 |
1984-12-04 |
James Ferrara |
Therapeutic device for administering medicaments through the skin
|
|
DE3572982D1
(en)
|
1984-03-06 |
1989-10-19 |
Takeda Chemical Industries Ltd |
Chemically modified lymphokine and production thereof
|
|
US4596556A
(en)
|
1985-03-25 |
1986-06-24 |
Bioject, Inc. |
Hypodermic injection apparatus
|
|
US5374548A
(en)
|
1986-05-02 |
1994-12-20 |
Genentech, Inc. |
Methods and compositions for the attachment of proteins to liposomes using a glycophospholipid anchor
|
|
MX9203291A
(es)
|
1985-06-26 |
1992-08-01 |
Liposome Co Inc |
Metodo para acoplamiento de liposomas.
|
|
GB8601597D0
(en)
|
1986-01-23 |
1986-02-26 |
Wilson R H |
Nucleotide sequences
|
|
US5225539A
(en)
|
1986-03-27 |
1993-07-06 |
Medical Research Council |
Recombinant altered antibodies and methods of making altered antibodies
|
|
US4946778A
(en)
|
1987-09-21 |
1990-08-07 |
Genex Corporation |
Single polypeptide chain binding molecules
|
|
EP0307434B2
(en)
|
1987-03-18 |
1998-07-29 |
Scotgen Biopharmaceuticals, Inc. |
Altered antibodies
|
|
US4790824A
(en)
|
1987-06-19 |
1988-12-13 |
Bioject, Inc. |
Non-invasive hypodermic injection device
|
|
US4941880A
(en)
|
1987-06-19 |
1990-07-17 |
Bioject, Inc. |
Pre-filled ampule and non-invasive hypodermic injection device assembly
|
|
GB8717430D0
(en)
|
1987-07-23 |
1987-08-26 |
Celltech Ltd |
Recombinant dna product
|
|
GB8720833D0
(en)
|
1987-09-04 |
1987-10-14 |
Celltech Ltd |
Recombinant dna product
|
|
US5677425A
(en)
|
1987-09-04 |
1997-10-14 |
Celltech Therapeutics Limited |
Recombinant antibody
|
|
GB8809129D0
(en)
|
1988-04-18 |
1988-05-18 |
Celltech Ltd |
Recombinant dna methods vectors and host cells
|
|
US5476996A
(en)
|
1988-06-14 |
1995-12-19 |
Lidak Pharmaceuticals |
Human immune system in non-human animal
|
|
US5223409A
(en)
|
1988-09-02 |
1993-06-29 |
Protein Engineering Corp. |
Directed evolution of novel binding proteins
|
|
GB8823869D0
(en)
|
1988-10-12 |
1988-11-16 |
Medical Res Council |
Production of antibodies
|
|
DE68925966T2
(de)
|
1988-12-22 |
1996-08-29 |
Kirin Amgen Inc |
Chemisch modifizierte granulocytenkolonie erregender faktor
|
|
US5530101A
(en)
|
1988-12-28 |
1996-06-25 |
Protein Design Labs, Inc. |
Humanized immunoglobulins
|
|
US5108921A
(en)
|
1989-04-03 |
1992-04-28 |
Purdue Research Foundation |
Method for enhanced transmembrane transport of exogenous molecules
|
|
US5208020A
(en)
|
1989-10-25 |
1993-05-04 |
Immunogen Inc. |
Cytotoxic agents comprising maytansinoids and their therapeutic use
|
|
US5312335A
(en)
|
1989-11-09 |
1994-05-17 |
Bioject Inc. |
Needleless hypodermic injection device
|
|
US5064413A
(en)
|
1989-11-09 |
1991-11-12 |
Bioject, Inc. |
Needleless hypodermic injection device
|
|
US6673986B1
(en)
|
1990-01-12 |
2004-01-06 |
Abgenix, Inc. |
Generation of xenogeneic antibodies
|
|
US6075181A
(en)
|
1990-01-12 |
2000-06-13 |
Abgenix, Inc. |
Human antibodies derived from immunized xenomice
|
|
DK0463151T3
(da)
|
1990-01-12 |
1996-07-01 |
Cell Genesys Inc |
Frembringelse af xenogene antistoffer
|
|
US6150584A
(en)
|
1990-01-12 |
2000-11-21 |
Abgenix, Inc. |
Human antibodies derived from immunized xenomice
|
|
US5427908A
(en)
|
1990-05-01 |
1995-06-27 |
Affymax Technologies N.V. |
Recombinant library screening methods
|
|
GB9015198D0
(en)
|
1990-07-10 |
1990-08-29 |
Brien Caroline J O |
Binding substance
|
|
US6172197B1
(en)
|
1991-07-10 |
2001-01-09 |
Medical Research Council |
Methods for producing members of specific binding pairs
|
|
US5874299A
(en)
|
1990-08-29 |
1999-02-23 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
|
US6255458B1
(en)
|
1990-08-29 |
2001-07-03 |
Genpharm International |
High affinity human antibodies and human antibodies against digoxin
|
|
DE69127627T2
(de)
|
1990-08-29 |
1998-02-19 |
Genpharm Int |
Produktion und Nützung nicht-menschliche transgentiere zur Produktion heterologe Antikörper
|
|
US5545806A
(en)
|
1990-08-29 |
1996-08-13 |
Genpharm International, Inc. |
Ransgenic non-human animals for producing heterologous antibodies
|
|
US5633425A
(en)
|
1990-08-29 |
1997-05-27 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
|
US5661016A
(en)
|
1990-08-29 |
1997-08-26 |
Genpharm International Inc. |
Transgenic non-human animals capable of producing heterologous antibodies of various isotypes
|
|
US5789650A
(en)
|
1990-08-29 |
1998-08-04 |
Genpharm International, Inc. |
Transgenic non-human animals for producing heterologous antibodies
|
|
US5625126A
(en)
|
1990-08-29 |
1997-04-29 |
Genpharm International, Inc. |
Transgenic non-human animals for producing heterologous antibodies
|
|
US6300129B1
(en)
|
1990-08-29 |
2001-10-09 |
Genpharm International |
Transgenic non-human animals for producing heterologous antibodies
|
|
US5770429A
(en)
|
1990-08-29 |
1998-06-23 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
|
US5814318A
(en)
|
1990-08-29 |
1998-09-29 |
Genpharm International Inc. |
Transgenic non-human animals for producing heterologous antibodies
|
|
US5877397A
(en)
|
1990-08-29 |
1999-03-02 |
Genpharm International Inc. |
Transgenic non-human animals capable of producing heterologous antibodies of various isotypes
|
|
CA2061703C
(en)
|
1992-02-20 |
2002-07-02 |
Rudolf E. Falk |
Formulations containing hyaluronic acid
|
|
CA2061566C
(en)
|
1992-02-20 |
2002-07-09 |
Rudolf E. Falk |
Treatment of disease employing hyaluronic acid and nsaids
|
|
ES2341666T3
(es)
|
1991-12-02 |
2010-06-24 |
Medimmune Limited |
Produccion de autoanticuerpos de repertorios de segmentos de anticue rpos expresados en la superficie de fagos.
|
|
CA2124967C
(en)
|
1991-12-17 |
2008-04-08 |
Nils Lonberg |
Transgenic non-human animals capable of producing heterologous antibodies
|
|
CA2130762C
(en)
|
1994-08-24 |
1999-07-06 |
Eva Anne Turley |
Treatment of disease and conditions associated with macrophage infiltration
|
|
US5714350A
(en)
|
1992-03-09 |
1998-02-03 |
Protein Design Labs, Inc. |
Increasing antibody affinity by altering glycosylation in the immunoglobulin variable region
|
|
US5383851A
(en)
|
1992-07-24 |
1995-01-24 |
Bioject Inc. |
Needleless hypodermic injection device
|
|
EP0754225A4
(en)
|
1993-04-26 |
2001-01-31 |
Genpharm Int |
HETEROLOGIC ANTIBODY-PRODUCING TRANSGENIC NON-HUMAN ANIMALS
|
|
AU691811B2
(en)
|
1993-06-16 |
1998-05-28 |
Celltech Therapeutics Limited |
Antibodies
|
|
EP0702553A1
(en)
|
1993-12-27 |
1996-03-27 |
BAXTER INTERNATIONAL INC. (a Delaware corporation) |
Water soluble non-immunogenic polyamide cross-linking agents
|
|
US6121022A
(en)
|
1995-04-14 |
2000-09-19 |
Genentech, Inc. |
Altered polypeptides with increased half-life
|
|
US5869046A
(en)
|
1995-04-14 |
1999-02-09 |
Genentech, Inc. |
Altered polypeptides with increased half-life
|
|
US6410690B1
(en)
|
1995-06-07 |
2002-06-25 |
Medarex, Inc. |
Therapeutic compounds comprised of anti-Fc receptor antibodies
|
|
US5811097A
(en)
|
1995-07-25 |
1998-09-22 |
The Regents Of The University Of California |
Blockade of T lymphocyte down-regulation associated with CTLA-4 signaling
|
|
JPH11513391A
(ja)
|
1995-10-03 |
1999-11-16 |
ザ スクリップス リサーチ インスティテュート |
Ｃｃ−１０６５ 及びズオカーマイシンのｃｂｉ 類縁体
|
|
AU728657B2
(en)
|
1996-03-18 |
2001-01-18 |
Board Of Regents, The University Of Texas System |
Immunoglobulin-like domains with increased half-lives
|
|
US5834597A
(en)
|
1996-05-20 |
1998-11-10 |
Protein Design Labs, Inc. |
Mutated nonactivating IgG2 domains and anti CD3 antibodies incorporating the same
|
|
US5922845A
(en)
|
1996-07-11 |
1999-07-13 |
Medarex, Inc. |
Therapeutic multispecific compounds comprised of anti-Fcα receptor antibodies
|
|
US7247302B1
(en)
|
1996-08-02 |
2007-07-24 |
Bristol-Myers Squibb Company |
Method for inhibiting immunoglobulin-induced toxicity resulting from the use of immunoglobulins in therapy and in vivo diagnosis
|
|
WO1998023289A1
(en)
|
1996-11-27 |
1998-06-04 |
The General Hospital Corporation |
MODULATION OF IgG BINDING TO FcRn
|
|
US6277375B1
(en)
|
1997-03-03 |
2001-08-21 |
Board Of Regents, The University Of Texas System |
Immunoglobulin-like domains with increased half-lives
|
|
WO1998042752A1
(en)
|
1997-03-21 |
1998-10-01 |
Brigham And Women's Hospital Inc. |
Immunotherapeutic ctla-4 binding peptides
|
|
JP2002512624A
(ja)
|
1997-05-21 |
2002-04-23 |
バイオベーション リミテッド |
非免疫原性タンパク質の製造方法
|
|
DK1068241T3
(da)
|
1998-04-02 |
2008-02-04 |
Genentech Inc |
Antistofvarianter og fragmenter deraf
|
|
US6194551B1
(en)
|
1998-04-02 |
2001-02-27 |
Genentech, Inc. |
Polypeptide variants
|
|
SI1068241T1
(sl)
|
1998-04-02 |
2007-12-31 |
Genentech Inc |
Protitelesne variante in njihovi fragmenti
|
|
US6528624B1
(en)
|
1998-04-02 |
2003-03-04 |
Genentech, Inc. |
Polypeptide variants
|
|
DK2180007T4
(da)
|
1998-04-20 |
2017-11-27 |
Roche Glycart Ag |
Glycosyleringsteknik for antistoffer til forbedring af antistofafhængig cellecytotoxicitet
|
|
GB9809951D0
(en)
|
1998-05-08 |
1998-07-08 |
Univ Cambridge Tech |
Binding molecules
|
|
HRP20010551B1
(hr)
|
1998-12-23 |
2013-05-31 |
Pfizer Inc. |
Humana monoklonalna antitijela za ctla-4
|
|
US6737056B1
(en)
|
1999-01-15 |
2004-05-18 |
Genentech, Inc. |
Polypeptide variants with altered effector function
|
|
MX353234B
(es)
|
1999-01-15 |
2018-01-08 |
Genentech Inc |
Variantes de polipeptidos con función efectora alterada.
|
|
DK1176195T3
(da)
|
1999-04-09 |
2013-06-24 |
Kyowa Hakko Kirin Co Ltd |
Fremgangsmåde til at kontrollere aktiviteten af immunologisk funktionelt molekyle
|
|
US20040031072A1
(en)
|
1999-05-06 |
2004-02-12 |
La Rosa Thomas J. |
Soy nucleic acid molecules and other molecules associated with transcription plants and uses thereof for plant improvement
|
|
EP1176981B1
(en)
|
1999-05-07 |
2005-11-30 |
Genentech, Inc. |
Treatment of autoimmune diseases with antagonists which bind to b cell surface markers
|
|
US20040146516A1
(en)
|
1999-06-17 |
2004-07-29 |
Utah Ventures Ii L.P. |
Lumen-exposed molecules and methods for targeted delivery
|
|
JP4118462B2
(ja)
|
1999-07-19 |
2008-07-16 |
株式会社リコー |
携帯電子機器
|
|
EP1074563A1
(en)
|
1999-08-02 |
2001-02-07 |
F. Hoffmann-La Roche Ag |
Chimeric polypeptides enhancing dimer formation through electrostatic interactions and disulfide bond, method for production and uses thereof
|
|
JP5004390B2
(ja)
|
1999-08-23 |
2012-08-22 |
デイナ ファーバー キャンサー インスティチュート，インコーポレイテッド |
新規ｂ７−４分子およびその用途
|
|
CA2589418A1
(en)
|
1999-08-24 |
2001-03-01 |
Medarex, Inc. |
Human ctla-4 antibodies and their uses
|
|
AU7721500A
(en)
|
1999-09-29 |
2001-04-30 |
Human Genome Sciences, Inc. |
Colon and colon cancer associated polynucleotides and polypeptides
|
|
PT1234031T
(pt)
|
1999-11-30 |
2017-06-26 |
Mayo Foundation |
B7-h1, uma nova molécula imunoregulatória
|
|
AU783473B2
(en)
|
1999-12-23 |
2005-10-27 |
Zymogenetics Inc. |
Soluble interleukin-20 receptor
|
|
US6610286B2
(en)
|
1999-12-23 |
2003-08-26 |
Zymogenetics, Inc. |
Method for treating inflammation using soluble receptors to interleukin-20
|
|
EP2248828A1
(en)
|
1999-12-23 |
2010-11-10 |
ZymoGenetics, Inc. |
Method for treating inflammation
|
|
US20070042392A1
(en)
|
2000-02-03 |
2007-02-22 |
Nuvelo, Inc. |
Novel nucleic acids and polypeptides
|
|
ATE336514T1
(de)
|
2000-02-11 |
2006-09-15 |
Merck Patent Gmbh |
Steigerung der zirkulierenden halbwertzeit von auf antikörpern basierenden fusionsproteinen
|
|
MXPA02009626A
(es)
|
2000-03-31 |
2003-05-14 |
Idec Pharma Corp |
Uso combinado de anticuerpos anti-citocina o antagonistas y anti-cd20 para el tratamiento de linfoma de celulas b.
|
|
HUP0002003A3
(en)
|
2000-05-24 |
2003-01-28 |
Pronuk Biotechnologia Kft |
Process and reagent-kit for determining of 5'-nucleotidase activity
|
|
NO311144B1
(no)
|
2000-05-25 |
2001-10-15 |
Pedersen Viggo Wahl |
Spylemekanisme for vannklosett
|
|
AU2001273224A1
(en)
|
2000-07-07 |
2002-01-21 |
University Of North Carolina At Chapel Hill |
Isolated polynucleotides encoding human 5'-nucleotide cn-ia and cn-ib, isolated proteins encoded by the same, and methods utilizing the same
|
|
AU2001277867B2
(en)
|
2000-07-11 |
2006-12-07 |
Research Corporation Technologies, Inc. |
Artificial antibody polypeptides
|
|
IL155977A0
(en)
|
2000-11-30 |
2003-12-23 |
Medarex Inc |
Transgenic transchromosomal rodents for making human antibodies
|
|
DE60143544D1
(de)
|
2000-12-12 |
2011-01-05 |
Medimmune Llc |
Moleküle mit längeren halbwertszeiten, zusammensetzungen und deren verwendung
|
|
DK1366067T3
(da)
|
2001-03-07 |
2012-10-22 |
Merck Patent Gmbh |
Ekspressionsteknologi for proteiner indeholdende en hybrid isotype-antistof-enhed
|
|
WO2002092780A2
(en)
|
2001-05-17 |
2002-11-21 |
Diversa Corporation |
Novel antigen binding molecules for therapeutic, diagnostic, prophylactic, enzymatic, industrial, and agricultural applications, and methods for generating and screening thereof
|
|
KR20030033007A
(ko)
|
2001-05-31 |
2003-04-26 |
코울터 파머수티컬, 인코포레이티드 |
세포독소, 약물전구체, 링커 및 이에 유용한 안정화제
|
|
CA2463879C
(en)
|
2001-10-25 |
2012-12-04 |
Genentech, Inc. |
Glycoprotein compositions
|
|
US6545530B1
(en)
|
2001-12-05 |
2003-04-08 |
Linear Technology Corporation |
Circuit and method for reducing quiescent current in a voltage reference circuit
|
|
US20040002587A1
(en)
|
2002-02-20 |
2004-01-01 |
Watkins Jeffry D. |
Fc region variants
|
|
US20040132101A1
(en)
|
2002-09-27 |
2004-07-08 |
Xencor |
Optimized Fc variants and methods for their generation
|
|
US7317091B2
(en)
|
2002-03-01 |
2008-01-08 |
Xencor, Inc. |
Optimized Fc variants
|
|
US20040110226A1
(en)
|
2002-03-01 |
2004-06-10 |
Xencor |
Antibody optimization
|
|
US8188231B2
(en)
|
2002-09-27 |
2012-05-29 |
Xencor, Inc. |
Optimized FC variants
|
|
US20040014194A1
(en)
|
2002-03-27 |
2004-01-22 |
Schering Corporation |
Beta-secretase crystals and methods for preparing and using the same
|
|
IL149820A0
(en)
|
2002-05-23 |
2002-11-10 |
Curetech Ltd |
Humanized immunomodulatory monoclonal antibodies for the treatment of neoplastic disease or immunodeficiency
|
|
DK1534335T4
(en)
|
2002-08-14 |
2015-10-05 |
Macrogenics Inc |
FCGAMMARIIB-SPECIFIC ANTIBODIES AND PROCEDURES FOR USE THEREOF
|
|
ATE541857T1
(de)
|
2002-09-27 |
2012-02-15 |
Xencor Inc |
Optimierte fc-varianten und herstellungsverfahren dafür
|
|
DK1562972T3
(da)
|
2002-10-15 |
2010-12-06 |
Facet Biotech Corp |
Modifikation af FcRn-bindingsaffiniteter eller serumhalveringstider for antistoffer ved mutagenese
|
|
US7355008B2
(en)
|
2003-01-09 |
2008-04-08 |
Macrogenics, Inc. |
Identification and engineering of antibodies with variant Fc regions and methods of using same
|
|
WO2004079013A1
(en)
*
|
2003-03-03 |
2004-09-16 |
Arizona Board Of Regents On Behalf Of The University Of Arizona |
Ecto-5’-nucleotidase (cd73) used in the diagnosis and the treatment of pancreatic cancer
|
|
US9051373B2
(en)
|
2003-05-02 |
2015-06-09 |
Xencor, Inc. |
Optimized Fc variants
|
|
CA2930485C
(en)
|
2003-05-14 |
2018-04-10 |
Immunogen, Inc. |
Maytansinoid-antibody conjugate compositions
|
|
US20100069614A1
(en)
|
2008-06-27 |
2010-03-18 |
Merus B.V. |
Antibody producing non-human mammals
|
|
JP2007501021A
(ja)
|
2003-05-30 |
2007-01-25 |
アレクシオン ファーマシューティカルズ， インコーポレイテッド |
遺伝子操作された定常領域を含む、抗体および融合タンパク質
|
|
CN1829533A
(zh)
|
2003-05-30 |
2006-09-06 |
阿莱克申药物公司 |
包含改造恒定区的抗体和融合蛋白
|
|
WO2005044853A2
(en)
|
2003-11-01 |
2005-05-19 |
Genentech, Inc. |
Anti-vegf antibodies
|
|
US7473531B1
(en)
|
2003-08-08 |
2009-01-06 |
Colora Corporation |
Pancreatic cancer targets and uses thereof
|
|
WO2005019258A2
(en)
|
2003-08-11 |
2005-03-03 |
Genentech, Inc. |
Compositions and methods for the treatment of immune related diseases
|
|
US8399618B2
(en)
|
2004-10-21 |
2013-03-19 |
Xencor, Inc. |
Immunoglobulin insertions, deletions, and substitutions
|
|
US8101720B2
(en)
|
2004-10-21 |
2012-01-24 |
Xencor, Inc. |
Immunoglobulin insertions, deletions and substitutions
|
|
US20060134105A1
(en)
|
2004-10-21 |
2006-06-22 |
Xencor, Inc. |
IgG immunoglobulin variants with optimized effector function
|
|
US20150071948A1
(en)
|
2003-09-26 |
2015-03-12 |
Gregory Alan Lazar |
Novel immunoglobulin variants
|
|
US8883147B2
(en)
|
2004-10-21 |
2014-11-11 |
Xencor, Inc. |
Immunoglobulins insertions, deletions, and substitutions
|
|
GB0324368D0
(en)
|
2003-10-17 |
2003-11-19 |
Univ Cambridge Tech |
Polypeptides including modified constant regions
|
|
PT1725249E
(pt)
|
2003-11-06 |
2014-04-10 |
Seattle Genetics Inc |
Compostos de monometilvalina capazes de conjugação a ligandos
|
|
WO2005070963A1
(en)
|
2004-01-12 |
2005-08-04 |
Applied Molecular Evolution, Inc |
Fc region variants
|
|
US7329353B2
(en)
|
2004-01-23 |
2008-02-12 |
Amgen Inc. |
LC/MS method of analyzing high molecular weight proteins
|
|
EP2053062A1
(en)
|
2004-03-24 |
2009-04-29 |
Xencor, Inc. |
Immunoglobin variants outside the Fc region
|
|
US7778814B2
(en)
|
2004-03-30 |
2010-08-17 |
Siemens Aktiengesellschaft |
Method and device for simulating an automation system
|
|
RU2402548C2
(ru)
|
2004-05-19 |
2010-10-27 |
Медарекс, Инк. |
Химические линкеры и их конъюгаты
|
|
CA2564076C
(en)
|
2004-05-19 |
2014-02-18 |
Medarex, Inc. |
Chemical linkers and conjugates thereof
|
|
MX2007000998A
(es)
|
2004-07-30 |
2007-07-11 |
Rinat Neuroscience Corp |
Anticuerpos dirigidos peptido beta-amiloide y procedimientos que usan los mismos.
|
|
PL2213683T3
(pl)
|
2004-08-04 |
2013-10-31 |
Mentrik Biotech Llc |
WARIANTY REGIONÓW Fc
|
|
TWI380996B
(zh)
|
2004-09-17 |
2013-01-01 |
Hoffmann La Roche |
抗ｏｘ４０ｌ抗體
|
|
WO2006047350A2
(en)
|
2004-10-21 |
2006-05-04 |
Xencor, Inc. |
IgG IMMUNOGLOBULIN VARIANTS WITH OPTIMIZED EFFECTOR FUNCTION
|
|
WO2006047340A2
(en)
|
2004-10-22 |
2006-05-04 |
Amgen Inc. |
Methods for refolding of recombinant antibodies
|
|
US8367805B2
(en)
|
2004-11-12 |
2013-02-05 |
Xencor, Inc. |
Fc variants with altered binding to FcRn
|
|
MX2007006117A
(es)
|
2004-11-23 |
2007-07-13 |
Pip Co Ltd |
Caja de llave de servicio de agua empotrada en la pared.
|
|
EP1847602B1
(en)
|
2005-01-12 |
2014-04-23 |
Kyowa Hakko Kirin Co., Ltd. |
STABILIZED HUMAN IgG2 ANTIBODIES
|
|
US7700099B2
(en)
|
2005-02-14 |
2010-04-20 |
Merck & Co., Inc. |
Non-immunostimulatory antibody and compositions containing the same
|
|
PT2343320T
(pt)
|
2005-03-25 |
2018-01-23 |
Gitr Inc |
Anticorpos anti-gitr e as suas utilizações
|
|
US7714016B2
(en)
|
2005-04-08 |
2010-05-11 |
Medarex, Inc. |
Cytotoxic compounds and conjugates with cleavable substrates
|
|
MX2007013978A
(es)
|
2005-05-09 |
2008-02-22 |
Ono Pharmaceutical Co |
Anticuerpos monoclonales humanos a muerte programada 1 (pd-1) y metodos para tratamiento de cancer utilizando anticuerpos anti-pd-1 solos o en combinacion con otros inmunoterapeuticos.
|
|
RS54876B1
(sr)
|
2005-05-10 |
2016-10-31 |
Incyte Holdings Corp |
Modulatori indoleamina 2,3-dioksigenaze i metode za upotrebu istih
|
|
US8163881B2
(en)
|
2005-05-31 |
2012-04-24 |
The Board Of Regents Of The University Of Texas System |
Immunoglobulin molecules with improved characteristics
|
|
CN105330741B
(zh)
|
2005-07-01 |
2023-01-31 |
E.R.施贵宝&圣斯有限责任公司 |
抗程序性死亡配体1(pd-l1)的人单克隆抗体
|
|
BRPI0617546A2
(pt)
|
2005-09-26 |
2011-07-26 |
Medarex Inc |
conjugado de fÁrmaco-anticorpo, formulaÇço farmacÊutica, mÉtodo para matar uma cÉlula de tumor, mÉtodo para retardar ou interromper o crescimento de um tumor em um sujeito mamÍfero e composto
|
|
WO2007038868A2
(en)
|
2005-10-03 |
2007-04-12 |
The University Of British Columbia |
Novel enediyne compound and uses thereof
|
|
JP5116686B2
(ja)
|
2005-10-26 |
2013-01-09 |
メダレックス インコーポレイテッド |
Ｃｃ−１０６５類似体の調製方法及び調製用化合物
|
|
US20080206246A1
(en)
|
2006-04-05 |
2008-08-28 |
Ravetch Jeffrey V |
Polypeptides with enhanced anti-inflammatory and decreased cytotoxic properties and relating methods
|
|
CA2627190A1
(en)
|
2005-11-10 |
2007-05-24 |
Medarex, Inc. |
Duocarmycin derivatives as novel cytotoxic compounds and conjugates
|
|
ES2540561T3
(es)
|
2005-12-20 |
2015-07-10 |
Incyte Corporation |
N-hidroxiamidinoheterociclos como moduladores de indolamina 2,3-dioxigenasa
|
|
PE20080102A1
(es)
|
2006-05-25 |
2008-02-11 |
Bristol Myers Squibb Co |
Conjugados de analogos de aziridinil-epotilona y composiciones farmaceuticas que comprenden los mismos
|
|
PE20080316A1
(es)
|
2006-05-25 |
2008-04-10 |
Bristol Myers Squibb Co |
Compuestos de aziridinil-epotilona
|
|
DE102006027624A1
(de)
|
2006-06-13 |
2007-12-20 |
Elexxion Gmbh |
Handstück für insbesondere medizinische Laseranwendungen
|
|
EP2386577A3
(en)
|
2006-06-21 |
2012-05-02 |
Oncotherapy Science, Inc. |
Tumor-targeting monoclonal antibodies to FZD10 and uses thereof
|
|
US20150030534A1
(en)
|
2013-07-26 |
2015-01-29 |
Rutgers, The State University Of New Jersey |
Antibody cocktails for breast cancer radioimmunotherapy
|
|
EP2078732B1
(en)
|
2006-07-10 |
2015-09-16 |
Fujita Health University |
Method of identifying a candidate diagnostic or therapeutic antibody using flow cytometry
|
|
CL2007002650A1
(es)
|
2006-09-19 |
2008-02-08 |
Incyte Corp |
Compuestos derivados de heterociclo n-hidroxiamino; composicion farmaceutica, util para tratar cancer, infecciones virales y desordenes neurodegenerativos entre otras.
|
|
JP5319532B2
(ja)
|
2006-09-19 |
2013-10-16 |
インサイト・コーポレイション |
インドールアミン２，３−ジオキシゲナーゼのモジュレーターとしてのｎ−ヒドロキシアミジノヘテロサイクル
|
|
US8455622B2
(en)
|
2006-12-01 |
2013-06-04 |
Seattle Genetics, Inc. |
Variant target binding agents and uses thereof
|
|
WO2008140603A2
(en)
|
2006-12-08 |
2008-11-20 |
Macrogenics, Inc. |
METHODS FOR THE TREATMENT OF DISEASE USING IMMUNOGLOBULINS HAVING FC REGIONS WITH ALTERED AFFINITIES FOR FCγR ACTIVATING AND FCγR INHIBITING
|
|
CL2007003622A1
(es)
|
2006-12-13 |
2009-08-07 |
Medarex Inc |
Anticuerpo monoclonal humano anti-cd19; composicion que lo comprende; y metodo de inhibicion del crecimiento de celulas tumorales.
|
|
TWI412367B
(zh)
|
2006-12-28 |
2013-10-21 |
Medarex Llc |
化學鏈接劑與可裂解基質以及其之綴合物
|
|
CN101616911A
(zh)
|
2007-02-21 |
2009-12-30 |
梅达莱克斯公司 |
具有单个氨基酸的化学连接物及其偶联物
|
|
JP2008278814A
(ja)
|
2007-05-11 |
2008-11-20 |
Igaku Seibutsugaku Kenkyusho:Kk |
アゴニスティック抗ヒトｇｉｔｒ抗体による免疫制御の解除とその応用
|
|
EP3173484B1
(en)
|
2007-05-30 |
2018-09-26 |
Postech Academy-Industry- Foundation |
Immunoglobulin fusion proteins
|
|
DK2167128T3
(da)
|
2007-07-17 |
2012-12-03 |
Merck Patent Gmbh |
Fremstillede anti-alfa-v-integrin hybrid-antistoffer
|
|
WO2009014708A2
(en)
|
2007-07-23 |
2009-01-29 |
Cell Genesys, Inc. |
Pd-1 antibodies in combination with a cytokine-secreting cell and methods of use thereof
|
|
DE102007036200A1
(de)
|
2007-08-02 |
2009-02-05 |
Knorr-Bremse Systeme für Nutzfahrzeuge GmbH |
Induktiver Weg- oder Drehwinkelsensor mit zwischen zwei Spulen angeordnetem Abschirmblech
|
|
EP2190861A4
(en)
|
2007-08-22 |
2011-03-30 |
Univ California |
ACTIVE BINDING POLYPEPTIDES AND METHOD FOR THEIR IDENTIFICATION AND USE
|
|
US20100226925A1
(en)
|
2007-09-14 |
2010-09-09 |
Amgen Inc. |
Homogeneous Antibody Populations
|
|
KR102467302B1
(ko)
|
2007-09-26 |
2022-11-14 |
추가이 세이야쿠 가부시키가이샤 |
항체 정상영역 개변체
|
|
MX2010003329A
(es)
|
2007-09-26 |
2010-04-27 |
Chugai Pharmaceutical Co Ltd |
Anticuerpo anti-receptor de il-6.
|
|
EP2584043A3
(en)
*
|
2007-09-28 |
2013-10-02 |
Chugai Seiyaku Kabushiki Kaisha |
Anti-glypican 3 antibody having improved kinetics in plasma
|
|
CA2700860C
(en)
|
2007-10-01 |
2016-07-19 |
Jonathan A. Terrett |
Human antibodies that bind mesothelin, and uses thereof
|
|
AU2008314697B2
(en)
|
2007-10-22 |
2013-08-29 |
Merck Serono S.A. |
Single IFN-beta fused to a mutated lgG Fc fragment
|
|
US8975081B2
(en)
|
2007-10-24 |
2015-03-10 |
Faron Pharmaceuticals Oy |
Biomarker for monitoring development of diseases and assessing the efficacy of therapies
|
|
FI20070795A0
(fi)
|
2007-10-24 |
2007-10-24 |
Faron Pharmaceuticals Oy |
Uusi biomarkkeri sairauksien kehittämisen tarkkailuun ja terapioiden tehon arviointiin
|
|
WO2009059278A1
(en)
|
2007-11-02 |
2009-05-07 |
Centocor, Inc. |
Semi-synthetic glp-1 peptide-fc fusion constructs, methods and uses
|
|
EP2227233B1
(en)
|
2007-11-30 |
2013-02-13 |
Newlink Genetics |
Ido inhibitors
|
|
MX2010005830A
(es)
|
2007-11-30 |
2010-09-14 |
Bristol Myers Squibb Co |
Conjugado de anticuerpo monoclonal anti-b7h4 - farmaco y metodos de uso del mismo.
|
|
JP2011505146A
(ja)
|
2007-11-30 |
2011-02-24 |
ブリストル−マイヤーズ スクイブ カンパニー |
タンパク質チロシンキナーゼ７（ｐｔｋ７）を対象とするモノクローナル抗体−パートナー分子複合体
|
|
US8815237B2
(en)
|
2007-12-05 |
2014-08-26 |
Massachusetts Institute Of Technology |
Aglycosylated immunoglobulin mutants
|
|
KR101840994B1
(ko)
|
2007-12-05 |
2018-03-21 |
추가이 세이야쿠 가부시키가이샤 |
항ｎｒ１０ 항체 및 그의 이용
|
|
EP2235059B1
(en)
|
2007-12-26 |
2015-02-18 |
Xencor, Inc. |
Fc variants with altered binding to fcrn
|
|
AU2008353145B2
(en)
|
2008-01-03 |
2013-09-12 |
Universite D' Aix-Marseille |
Bitherapy and tritherapy used for treating an HIV-positive patient
|
|
MX2010008578A
(es)
|
2008-02-08 |
2010-11-10 |
Medimmune Llc |
Anticuerpos anti-receptor 1 de interferon alfa con afinidad reducida al ligando fc.
|
|
WO2009114335A2
(en)
|
2008-03-12 |
2009-09-17 |
Merck & Co., Inc. |
Pd-1 binding proteins
|
|
JP2011516603A
(ja)
|
2008-04-17 |
2011-05-26 |
アブリンクス エン．ヴェー． |
血清タンパク質と結合することが可能なペプチド、並びにこれを含む化合物、構築物及びポリペプチド
|
|
PL2282773T3
(pl)
|
2008-05-02 |
2014-08-29 |
Seattle Genetics Inc |
Sposoby i kompozycje do wytwarzania przeciwciał i pochodnych przeciwciał o obniżonej fukozylacji rdzeniowej
|
|
AR072999A1
(es)
|
2008-08-11 |
2010-10-06 |
Medarex Inc |
Anticuerpos humanos que se unen al gen 3 de activacion linfocitaria (lag-3) y los usos de estos
|
|
EP2356131A4
(en)
|
2008-12-08 |
2012-09-12 |
Tegopharm Corp |
MASKING LIGANDS FOR REVERSIBLE INHIBITION OF VERSATILE COMPOUNDS
|
|
BRPI0917592B1
(pt)
|
2008-12-09 |
2021-08-17 |
Genentech, Inc |
Anticorpo anti-pd-l1, composição, artigos manufaturados e usos de uma composição
|
|
ES2610356T3
(es)
|
2009-02-03 |
2017-04-27 |
Amunix Operating Inc. |
Polipéptidos recombinantes extendidos y composiciones que comprenden los mismos
|
|
US9228017B2
(en)
|
2009-03-19 |
2016-01-05 |
Chugai Seiyaku Kabushiki Kaisha |
Antibody constant region variant
|
|
EP3674317B1
(en)
|
2009-03-19 |
2024-12-11 |
Chugai Seiyaku Kabushiki Kaisha |
Antibody constant region variant
|
|
US20110007023A1
(en)
|
2009-07-09 |
2011-01-13 |
Sony Ericsson Mobile Communications Ab |
Display device, touch screen device comprising the display device, mobile device and method for sensing a force on a display device
|
|
US8394922B2
(en)
|
2009-08-03 |
2013-03-12 |
Medarex, Inc. |
Antiproliferative compounds, conjugates thereof, methods therefor, and uses thereof
|
|
RU2595409C2
(ru)
|
2009-09-03 |
2016-08-27 |
Мерк Шарп И Доум Корп., |
Анти-gitr-антитела
|
|
US10150808B2
(en)
|
2009-09-24 |
2018-12-11 |
Chugai Seiyaku Kabushiki Kaisha |
Modified antibody constant regions
|
|
WO2011056652A1
(en)
|
2009-10-28 |
2011-05-12 |
Newlink Genetics |
Imidazole derivatives as ido inhibitors
|
|
JO3437B1
(ar)
|
2009-10-30 |
2019-10-20 |
Esai R & D Man Co Ltd |
أجسام مضادة محسنة مضادة للفراكتالكين البشري واستخداماتها
|
|
RS60033B1
(sr)
|
2009-11-24 |
2020-04-30 |
Medimmune Ltd |
Ciljano vezujući agensi usmereni na b7-h1
|
|
PT2506871T
(pt)
|
2009-11-30 |
2016-11-07 |
Janssen Biotech Inc |
Mutantes de fc de anticorpos com funções efetoras inutilizadas
|
|
SG181477A1
(en)
|
2009-12-10 |
2012-07-30 |
Regeneron Pharma |
Mice that make heavy chain antibodies
|
|
HUE026201T2
(en)
|
2009-12-10 |
2016-05-30 |
Hoffmann La Roche |
Antibodies binding to human CSF1R extracellular domain 4 and their use
|
|
US20120021409A1
(en)
|
2010-02-08 |
2012-01-26 |
Regeneron Pharmaceuticals, Inc. |
Common Light Chain Mouse
|
|
NZ631363A
(en)
|
2010-02-08 |
2016-05-27 |
Regeneron Pharma |
Common light chain mouse
|
|
SI3053932T1
(sl)
|
2010-02-19 |
2021-01-29 |
Xencor, Inc. |
Novi CTLA4-IG imunoadhezini
|
|
JP5889181B2
(ja)
|
2010-03-04 |
2016-03-22 |
中外製薬株式会社 |
抗体定常領域改変体
|
|
LT2542256T
(lt)
|
2010-03-04 |
2019-10-25 |
Macrogenics Inc |
Su b7-h3 reaguojantys antikūnai, jų imunologiškai aktyvūs fragmentai ir jų naudojimas
|
|
EP2542587A1
(en)
|
2010-03-05 |
2013-01-09 |
F. Hoffmann-La Roche AG |
Antibodies against human csf-1r and uses thereof
|
|
WO2011131407A1
(en)
|
2010-03-05 |
2011-10-27 |
F. Hoffmann-La Roche Ag |
Antibodies against human csf-1r and uses thereof
|
|
CN102971340A
(zh)
|
2010-03-29 |
2013-03-13 |
酵活有限公司 |
具有增强的或抑制的效应子功能的抗体
|
|
CN105175532B
(zh)
|
2010-04-13 |
2023-01-17 |
百时美施贵宝公司 |
结合pcsk9的基于纤连蛋白的支架域蛋白质
|
|
CN107019804A
(zh)
|
2010-04-15 |
2017-08-08 |
西雅图基因公司 |
靶向吡咯并苯并二氮杂卓结合物
|
|
BR112012026410B8
(pt)
|
2010-04-15 |
2023-01-31 |
Spirogen Dev Sarl |
Composto e conjugado de pirrolobenzodiazepinas e usos dos mesmos
|
|
WO2012007783A1
(en)
|
2010-07-13 |
2012-01-19 |
Institut Gustave Roussy |
Kits and methods for detecting the ability to induce an immunogenic cancer cell death in a subject
|
|
WO2011131246A1
(en)
|
2010-04-22 |
2011-10-27 |
Institut Gustave Roussy |
Compounds and uses thereof to induce an immunogenic cancer cell death in a subject
|
|
US8865653B2
(en)
|
2010-04-22 |
2014-10-21 |
Institut Gustave Roussy |
Method of treatment for immunogenic treatment resistant cancer
|
|
EP2806034B1
(en)
|
2010-04-22 |
2017-06-28 |
Institut Gustave Roussy |
Compounds and uses thereof to induce an immunogenic cancer cell death in a subject
|
|
US8828944B2
(en)
|
2010-04-22 |
2014-09-09 |
Institut Gustave Roussy |
Compounds and uses thereof to induce an immunogenic cancer cell death in a subject
|
|
TW201138808A
(en)
|
2010-05-03 |
2011-11-16 |
Bristol Myers Squibb Co |
Serum albumin binding molecules
|
|
SG185035A1
(en)
|
2010-05-04 |
2012-11-29 |
Five Prime Therapeutics Inc |
Antibodies that bind csf1r
|
|
PL2480676T3
(pl)
|
2010-06-22 |
2016-10-31 |
|
Mysz wykazująca ekspresję hybrydowego łańcucha lekkiego immunoglobuliny
|
|
US8907053B2
(en)
|
2010-06-25 |
2014-12-09 |
Aurigene Discovery Technologies Limited |
Immunosuppression modulating compounds
|
|
US20130123345A1
(en)
|
2010-07-23 |
2013-05-16 |
The Ohio State University |
Method of treating a viral infection dysfunction by disrupting an adenosine receptor pathway
|
|
DK3029066T3
(da)
|
2010-07-29 |
2019-05-20 |
Xencor Inc |
Antistoffer med modificerede isoelektriske punkter
|
|
KR20130136443A
(ko)
|
2010-07-30 |
2013-12-12 |
노파르티스 아게 |
피브로넥틴 크레이들 분자 및 그의 라이브러리
|
|
WO2012031320A1
(en)
|
2010-09-06 |
2012-03-15 |
Peter Maccallum Cancer Institute |
Cancer diagnostic
|
|
SI2614082T1
(sl)
|
2010-09-09 |
2018-12-31 |
Pfizer Inc. |
Molekule, ki vežejo 4-1BB
|
|
HRP20181438T1
(hr)
|
2010-10-29 |
2018-11-16 |
Perseus Proteomics Inc. |
Protutijelo protiv cdh3 s visokom sposobnošću internaliziranja
|
|
AU2011349502B2
(en)
|
2010-12-20 |
2016-12-22 |
The Rockefeller University |
Modulating agonistic TNFR antibodies
|
|
JP6261341B2
(ja)
*
|
2011-02-01 |
2018-01-17 |
ゲンマブ エー／エス |
Ｃｄ７４に対するヒト抗体および抗体−薬物コンジュゲート
|
|
SG192945A1
(en)
|
2011-02-25 |
2013-09-30 |
Chugai Pharmaceutical Co Ltd |
Fcgriib-specific fc antibody
|
|
US9469676B2
(en)
|
2011-04-13 |
2016-10-18 |
Bristol-Myers Squibb Company |
Fc fusion proteins comprising novel linkers or arrangements
|
|
NO2694640T3
(esLanguage)
|
2011-04-15 |
2018-03-17 |
|
|
|
WO2012145493A1
(en)
|
2011-04-20 |
2012-10-26 |
Amplimmune, Inc. |
Antibodies and other molecules that bind b7-h1 and pd-1
|
|
US8852599B2
(en)
|
2011-05-26 |
2014-10-07 |
Bristol-Myers Squibb Company |
Immunoconjugates, compositions for making them, and methods of making and use
|
|
CN103987718A
(zh)
|
2011-09-20 |
2014-08-13 |
斯皮罗根有限公司 |
作为非对称二聚体pbd化合物用于内含在靶向结合物中的吡咯并苯并二氮杂卓
|
|
WO2013095738A2
(en)
|
2011-09-27 |
2013-06-27 |
Mapp Biopharmaceutical, Inc. |
Monoclonal antibodies with altered affinities for human fcyri, fcyrllla, and c1q proteins
|
|
ES2402038B1
(es)
|
2011-10-14 |
2013-11-25 |
Josep Ramon Viola Terès |
Base para palé y palé provisto de esta
|
|
MX2014006673A
(es)
|
2011-12-07 |
2014-09-04 |
Amgen Inc |
Separacion de la isoforma de disulfuro de la igg2.
|
|
US10023643B2
(en)
|
2011-12-15 |
2018-07-17 |
Hoffmann-La Roche Inc. |
Antibodies against human CSF-1R and uses thereof
|
|
EA201892339A3
(ru)
|
2011-12-19 |
2019-06-28 |
Дзе Рокфеллер Юниверсити |
Несиалированный выделенный полипептид, способ получения указанного полипептида и фармацевтическая композиция для лечения воспалительного заболевания
|
|
EP2807194A4
(en)
|
2012-01-27 |
2015-12-02 |
Gliknik Inc |
FUSION PROTEINS WITH IGG2 HINGEOMS
|
|
MX2014008961A
(es)
|
2012-02-06 |
2014-10-14 |
Genentech Inc |
Composiciones y metodos para utilizar inhibidores de csf1r.
|
|
PE20141791A1
(es)
|
2012-02-13 |
2014-11-19 |
Bristol Myers Squibb Co |
Compuestos de enediino, conjugados de los mismos y sus usos y metodos
|
|
AR090263A1
(es)
|
2012-03-08 |
2014-10-29 |
Hoffmann La Roche |
Terapia combinada de anticuerpos contra el csf-1r humano y las utilizaciones de la misma
|
|
JP2015517490A
(ja)
|
2012-05-11 |
2015-06-22 |
ファイブ プライム セラピューティックス インコーポレイテッド |
コロニー刺激因子１受容体（ｃｓｆ１ｒ）を結合させる抗体を用いて状態を治療する方法
|
|
CA3213528A1
(en)
|
2012-05-15 |
2013-11-21 |
Bristol-Myers Squibb Company |
Cancer immunotherapy by disrupting pd-1/pd-l1 signaling
|
|
WO2014003553A1
(en)
|
2012-06-27 |
2014-01-03 |
Arthrogen B.V. |
Combination for treating an inflammatory disorder
|
|
AR091649A1
(es)
|
2012-07-02 |
2015-02-18 |
Bristol Myers Squibb Co |
Optimizacion de anticuerpos que se fijan al gen de activacion de linfocitos 3 (lag-3) y sus usos
|
|
WO2014036357A1
(en)
|
2012-08-31 |
2014-03-06 |
Five Prime Therapeutics, Inc. |
Methods of treating conditions with antibodies that bind colony stimulating factor 1 receptor (csf1r)
|
|
SI3835310T1
(sl)
|
2012-09-13 |
2024-07-31 |
Bristol-Myers Squibb Company |
Proteini skafold domene na osnovi fibronektina, ki se vežejo na miostatin
|
|
PT2956173T
(pt)
|
2013-02-14 |
2017-06-26 |
Bristol Myers Squibb Co |
Compostos de tubulisina, métodos de produção e utilização
|
|
WO2014153424A1
(en)
|
2013-03-19 |
2014-09-25 |
La Jolla Institute For Allergy And Immunology |
Reducing diabetes in patients receiving hmg-coa reductase inhibitors (statins)
|
|
KR102049991B1
(ko)
|
2013-03-28 |
2019-12-02 |
삼성전자주식회사 |
항 c-Met/항 Her2 이중 특이 항체
|
|
CN103278634B
(zh)
*
|
2013-05-16 |
2015-01-07 |
中国科学院近代物理研究所 |
Cd73作为肾透明细胞癌干细胞表面标志物的应用
|
|
WO2015035606A1
(en)
|
2013-09-13 |
2015-03-19 |
Beigene, Ltd. |
Anti-pd1 antibodies and their use as therapeutics and diagnostics
|
|
KR20210141789A
(ko)
|
2013-09-20 |
2021-11-23 |
브리스톨-마이어스 스큅 컴퍼니 |
종양을 치료하기 위한 항-lag-3 항체 및 항-pd-1 항체의 조합물
|
|
MX2016008667A
(es)
|
2013-12-30 |
2017-02-02 |
Epimab Biotherapeutics Inc |
Inmunoglobulina con fab en tandem y usos de esta.
|
|
AU2015237864B2
(en)
|
2014-03-24 |
2020-12-03 |
Cancer Research Technology Limited |
Modified antibodies containing modified IgG2 domains which elicit agonist or antagonistic properties and use thereof
|
|
JP6657182B2
(ja)
|
2014-04-25 |
2020-03-04 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
癌治療用のｃｄ７３阻害剤としてのプリン誘導体
|
|
PT3151921T
(pt)
|
2014-06-06 |
2019-11-21 |
Bristol Myers Squibb Co |
Anticorpos contra recetor do fator de necrose tumoral induzido por glicocorticoide e utilizações dos mesmos
|
|
CN106852149B
(zh)
|
2014-10-10 |
2021-08-27 |
依奈特制药公司 |
Cd73阻断
|
|
SG11201703332SA
(en)
|
2014-11-10 |
2017-05-30 |
Medimmune Ltd |
Binding molecules specific for cd73 and uses thereof
|
|
EP3789403A1
(en)
|
2014-11-11 |
2021-03-10 |
MedImmune Limited |
Therapeutic combinations comprising anti-cd73 antibodies and a2a receptor inhibitor and uses thereof
|
|
EP3221346B1
(en)
|
2014-11-21 |
2020-09-02 |
Bristol-Myers Squibb Company |
Antibodies comprising modified heavy constant regions
|
|
UY36404A
(es)
|
2014-11-21 |
2016-06-01 |
Bristol Myers Squibb Company Una Corporación Del Estado De Delaware |
ANTICUERPOS MONOCLONALES (Ab) COMO DETECTORES DE CD73 E INHIBIDORES DE SU ACTIVIDAD ENZIMÁTICA, Y COMPOSICIONES QUE LOS CONTIENEN
|
|
AU2016356780A1
(en)
|
2015-11-19 |
2018-06-28 |
Bristol-Myers Squibb Company |
Antibodies against glucocorticoid-induced tumor necrosis factor receptor (GITR) and uses thereof
|
|
CA3016187A1
(en)
|
2016-03-04 |
2017-09-08 |
Bristol-Myers Squibb Company |
Combination therapy with anti-cd73 antibodies
|
|
WO2018218056A1
(en)
|
2017-05-25 |
2018-11-29 |
Birstol-Myers Squibb Company |
Antibodies comprising modified heavy constant regions
|
|
KR102847736B1
(ko)
|
2017-05-25 |
2025-08-18 |
브리스톨-마이어스 스큅 컴퍼니 |
변형된 IgG1 Fc 도메인 및 그와의 항-CD40 도메인 항체 융합체
|
|
EP3630831B1
(en)
|
2017-05-25 |
2022-06-15 |
Bristol-Myers Squibb Company |
Antagonistic cd40 monoclonal antibodies and uses thereof
|
|
JP2021521182A
(ja)
|
2018-04-12 |
2021-08-26 |
ブリストル−マイヤーズ スクイブ カンパニーＢｒｉｓｔｏｌ−Ｍｙｅｒｓ Ｓｑｕｉｂｂ Ｃｏｍｐａｎｙ |
Ｃｄ７３アンタゴニストとｐｄ−１／ｐｄ−ｌ１軸アンタゴニストの組み合わせ治療
|
|
CN113348177A
(zh)
|
2018-11-28 |
2021-09-03 |
百时美施贵宝公司 |
包含经修饰的重链恒定区的抗体
|