|
CN101098854B
(zh)
|
2004-07-23 |
2012-12-05 |
恩多塞特公司 |
二价连接体及其轭合物
|
|
WO2008112873A2
(en)
|
2007-03-14 |
2008-09-18 |
Endocyte, Inc. |
Binding ligand linked drug delivery conjugates of tubulysins
|
|
EP3569251A1
(en)
|
2007-06-25 |
2019-11-20 |
Endocyte, Inc. |
Conjugates containing hydrophilic spacer linkers
|
|
US9877965B2
(en)
|
2007-06-25 |
2018-01-30 |
Endocyte, Inc. |
Vitamin receptor drug delivery conjugates for treating inflammation
|
|
WO2013126797A1
(en)
|
2012-02-24 |
2013-08-29 |
Purdue Research Foundation |
Cholecystokinin b receptor targeting for imaging and therapy
|
|
US20140080175A1
(en)
|
2012-03-29 |
2014-03-20 |
Endocyte, Inc. |
Processes for preparing tubulysin derivatives and conjugates thereof
|
|
US20140079636A1
(en)
|
2012-04-16 |
2014-03-20 |
Dinesh U. Chimmanamada |
Targeted therapeutics
|
|
EP2849797B1
(en)
|
2012-05-15 |
2019-12-18 |
Concortis Biosystems, Corp |
Drug-conjugates, conjugation methods, and uses thereof
|
|
HK1212618A1
(zh)
|
2012-10-16 |
2016-06-17 |
恩多塞特公司 |
含有非天然氨基酸的藥物遞送綴合物以及其使用方法
|
|
US9089614B2
(en)
|
2012-12-21 |
2015-07-28 |
Bioalliance C.V. |
Hydrophilic self-immolative linkers and conjugates thereof
|
|
MX368258B
(es)
|
2013-03-15 |
2019-09-25 |
Zymeworks Inc |
Compuestos citotoxicos y antimitoticos y metodos de uso de los mismos.
|
|
CA2914448A1
(en)
|
2013-06-12 |
2014-12-18 |
Muhammad Naveed Yousaf |
Compounds for promoting liposomal and cellular adhesion and compositions and methods of use thereof
|
|
WO2015038649A1
(en)
|
2013-09-10 |
2015-03-19 |
Synta Pharmaceuticals Corp. |
Targeted therapeutics
|
|
WO2015057876A1
(en)
|
2013-10-15 |
2015-04-23 |
Sorrento Therapeutics Inc. |
Drug-conjugates with a targeting molecule and two different drugs
|
|
BR112016007622A2
(pt)
|
2013-10-15 |
2018-01-23 |
Seattle Genetics, Inc. |
composto, composição farmacêutica, conjugado de ligante-droga, e, método para tratar câncer
|
|
WO2015066053A2
(en)
|
2013-10-28 |
2015-05-07 |
Synta Pharmaceuticals Corp. |
Targeted therapeutics
|
|
CA2935077C
(en)
|
2013-12-27 |
2022-03-15 |
Geoffrey C. Winters |
Sulfonamide-containing linkage systems for drug conjugates
|
|
RU2714933C2
(ru)
|
2013-12-27 |
2020-02-21 |
Займворкс Инк. |
Конъюгаты var2csa-лекарственное средство
|
|
US10183970B2
(en)
|
2014-01-28 |
2019-01-22 |
Tube Pharmaceuticals Gmbh |
Cytotoxic tubulysin compounds for conjugation
|
|
JP2017505777A
(ja)
|
2014-01-29 |
2017-02-23 |
シンタ ファーマスーティカルズ コーポレーション |
標的化治療薬
|
|
GB201402006D0
(en)
*
|
2014-02-06 |
2014-03-26 |
Oncomatryx Biopharma S L |
Antibody-drug conjugates and immunotoxins
|
|
CA2941618A1
(en)
|
2014-03-03 |
2015-09-11 |
Synta Pharmaceuticals Corp. |
Targeted therapeutics
|
|
WO2015143004A1
(en)
|
2014-03-18 |
2015-09-24 |
Synta Pharmaceuticals Corp. |
Targeted therapeutics
|
|
ES2883023T3
(es)
|
2014-05-28 |
2021-12-03 |
Agensys Inc |
Derivados de péptidos de dolaproína-dolaisoleuina citotóxicos para el tratamiento del cáncer
|
|
JP2017528418A
(ja)
|
2014-06-20 |
2017-09-28 |
バイオアライアンス コマンディテール フェンノートシャップ |
抗葉酸受容体アルファ（ｆｒａ）抗体−薬物コンジュゲート及びその使用方法
|
|
ES2774428T3
(es)
|
2014-07-11 |
2020-07-21 |
Genmab As |
Anticuerpos que se unen a AXL
|
|
SG10202006504QA
(en)
*
|
2014-09-11 |
2020-08-28 |
Seattle Genetics Inc |
Targeted delivery of tertiary amine-containing drug substances
|
|
KR102494557B1
(ko)
*
|
2014-09-17 |
2023-02-02 |
자임워크스 비씨 인코포레이티드 |
세포독성 및 항유사분열성 화합물, 그리고 이를 이용하는 방법
|
|
EP3218009B1
(en)
|
2014-10-14 |
2021-04-07 |
Polytherics Limited |
Process for the conjugation of a peptide or protein with a reagent comprising a leaving group including a portion of peg
|
|
US10077287B2
(en)
|
2014-11-10 |
2018-09-18 |
Bristol-Myers Squibb Company |
Tubulysin analogs and methods of making and use
|
|
CA2969892A1
(en)
*
|
2014-12-08 |
2016-06-16 |
Sorrento Therapeutics, Inc. |
C-met antibody drug conjugate
|
|
US9968683B2
(en)
|
2014-12-17 |
2018-05-15 |
Organolinx Corp. |
Method for conjugating molecules
|
|
EP3250238B1
(en)
*
|
2015-01-28 |
2022-06-01 |
Sorrento Therapeutics, Inc. |
Antibody drug conjugates
|
|
EP3253212A4
(en)
*
|
2015-02-06 |
2018-09-19 |
Sorrento Therapeutics, Inc. |
Antibody drug conjugates
|
|
US20180177890A1
(en)
*
|
2015-02-15 |
2018-06-28 |
Jiangsu Hengrui Medicine Co., Ltd. |
Ligand-cytotoxic drug conjugate, preparation method thereof, and use thereof
|
|
CN106279352B
(zh)
*
|
2015-05-29 |
2020-05-22 |
上海新理念生物医药科技有限公司 |
海兔毒素10的衍生物及其应用
|
|
EP3308801A4
(en)
|
2015-06-09 |
2019-02-27 |
XDCExplorer (Shanghai) Co., Ltd. |
ANTIBODY-ACTIVE CONJUGATE, INTERMEDIATE PRODUCT, METHOD OF MANUFACTURE, PHARMACEUTICAL COMPOSITION AND USE THEREOF
|
|
LT3319993T
(lt)
|
2015-07-10 |
2020-05-11 |
Genmab A/S |
Axl specifiniai antikūno-vaistokonjugatai, skirti vėžiui gydyti
|
|
NZ739830A
(en)
|
2015-07-12 |
2021-12-24 |
Hangzhou Dac Biotech Co Ltd |
Bridge linkers for conjugation of cell-binding molecules
|
|
US9839687B2
(en)
|
2015-07-15 |
2017-12-12 |
Suzhou M-Conj Biotech Co., Ltd. |
Acetylenedicarboxyl linkers and their uses in specific conjugation of a cell-binding molecule
|
|
WO2017054080A1
(en)
*
|
2015-09-29 |
2017-04-06 |
Zymeworks Inc. |
Cytotoxic and anti-mitotic compounds, and methods of using the same
|
|
US10722593B2
(en)
*
|
2015-10-02 |
2020-07-28 |
Sirenas Llc |
Anti-cancer compounds and conjugates thereof
|
|
TWI660741B
(zh)
|
2015-11-03 |
2019-06-01 |
財團法人工業技術研究院 |
抗體藥物複合物及其製造方法
|
|
CN106729743B
(zh)
*
|
2015-11-23 |
2021-09-21 |
四川科伦博泰生物医药股份有限公司 |
抗ErbB2抗体-药物偶联物及其组合物、制备方法和应用
|
|
US11793880B2
(en)
|
2015-12-04 |
2023-10-24 |
Seagen Inc. |
Conjugates of quaternized tubulysin compounds
|
|
SG11201804268RA
(en)
|
2015-12-04 |
2018-06-28 |
Seattle Genetics Inc |
Conjugates of quaternized tubulysin compounds
|
|
ES2880731T3
(es)
|
2016-01-08 |
2021-11-25 |
Altrubio Inc |
Anticuerpos anti-PSGL-1 tetravalentes y usos de los mismos
|
|
CN107029244B
(zh)
|
2016-02-04 |
2021-04-27 |
浙江昭华生物医药有限公司 |
抗her2抗体-药物偶联物及其应用
|
|
KR102456433B1
(ko)
|
2016-03-02 |
2022-10-19 |
에자이 알앤드디 매니지먼트 가부시키가이샤 |
에리불린-기반 항체-약물 콘주게이트 및 사용 방법
|
|
BR112018069273A2
(pt)
|
2016-03-25 |
2019-01-22 |
Seattle Genetics Inc |
métodos para preparação de um composto e para tratamento de um indivíduo com uma malignidade hematológica, composto, composição, e, intermediário ligante de fármaco ou composto ligante de fármaco
|
|
CN108779146B
(zh)
|
2016-03-29 |
2022-03-18 |
东丽株式会社 |
肽衍生物及其用途
|
|
US20170281758A1
(en)
*
|
2016-03-29 |
2017-10-05 |
Sorrento Therapeutics, Inc. |
Calicheamicin antibody drug conjugates linking an amidoacetyl group to a sugar moiety on calicheamicin
|
|
MA45328A
(fr)
|
2016-04-01 |
2019-02-06 |
Avidity Biosciences Llc |
Compositions acide nucléique-polypeptide et utilisations de celles-ci
|
|
EP3471771A4
(en)
*
|
2016-05-31 |
2020-04-15 |
Sorrento Therapeutics, Inc. |
ANTIBODY CONJUGATES HAVING AMATOXIN DERIVATIVES AS A MEDICINAL PRODUCT
|
|
US10111966B2
(en)
|
2016-06-17 |
2018-10-30 |
Magenta Therapeutics, Inc. |
Methods for the depletion of CD117+ cells
|
|
CN108697809A
(zh)
*
|
2016-08-23 |
2018-10-23 |
四川科伦博泰生物医药股份有限公司 |
一种抗体-药物偶联物及其制备方法和应用
|
|
US10517958B2
(en)
|
2016-10-04 |
2019-12-31 |
Zymeworks Inc. |
Compositions and methods for the treatment of platinum-drug resistant cancer
|
|
CN108101825B
(zh)
*
|
2016-11-25 |
2022-02-22 |
迈威(上海)生物科技股份有限公司 |
用于抗体-药物偶联的双取代马来酰胺类连接子及其制备方法和用途
|
|
CN109810039B
(zh)
*
|
2017-11-22 |
2021-11-12 |
迈威(上海)生物科技股份有限公司 |
一种用于抗体-药物偶联的双取代马来酰胺类连接子及其制备方法和用途
|
|
CN110088086B
(zh)
*
|
2016-11-25 |
2022-12-16 |
迈威(上海)生物科技股份有限公司 |
用于抗体-药物偶联的双取代马来酰胺类连接子及其制备方法和用途
|
|
US10864279B2
(en)
|
2016-12-16 |
2020-12-15 |
Industrial Technology Research Institute |
Linker-drug and antibody-drug conjugate (ADC) employing the same
|
|
WO2018129384A1
(en)
|
2017-01-06 |
2018-07-12 |
Avidity Biosciences Llc |
Nucleic acid-polypeptide compositions and methods of inducing exon skipping
|
|
US10576161B2
(en)
|
2017-01-20 |
2020-03-03 |
Magenta Therapeutics, Inc. |
Compositions and methods for the depletion of CD137+ cells
|
|
US11730822B2
(en)
|
2017-03-24 |
2023-08-22 |
Seagen Inc. |
Process for the preparation of glucuronide drug-linkers and intermediates thereof
|
|
MX2019011957A
(es)
*
|
2017-04-06 |
2019-11-07 |
Hangzhou Dac Biotech Co Ltd |
Conjugacion de un farmaco citotoxico con enlace bis.
|
|
EP3617221A4
(en)
|
2017-04-19 |
2021-04-14 |
Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. |
CYTOTOXIN AND CONJUGATE, USES THEREOF AND MANUFACTURING PROCESSES THEREFORE
|
|
IL299893A
(en)
|
2017-06-20 |
2023-03-01 |
Madrigal Pharmaceuticals Inc |
prescribed medications
|
|
JP7359700B2
(ja)
*
|
2017-06-20 |
2023-10-11 |
ソレント・セラピューティクス・インコーポレイテッド |
Ｃｄ３８抗体薬物コンジュゲート
|
|
JP2020524156A
(ja)
|
2017-06-20 |
2020-08-13 |
マドリガル ファーマシューティカルズ インコーポレイテッドＭａｄｒｉｇａｌ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ，Ｉｎｃ． |
標的治療薬を含む併用療法
|
|
GB201711809D0
(en)
|
2017-07-21 |
2017-09-06 |
Governors Of The Univ Of Alberta |
Antisense oligonucleotide
|
|
AU2018308088B2
(en)
|
2017-07-25 |
2025-05-29 |
Truebinding, Inc. |
Treating cancer by blocking the interaction of TIM-3 and its ligand
|
|
US10799598B2
(en)
|
2017-08-01 |
2020-10-13 |
Sorrento Therapeutics, Inc. |
Disulfide bridging conjugates
|
|
JP7202301B2
(ja)
|
2017-08-10 |
2023-01-11 |
住友ファーマ株式会社 |
ヘミアスタリン誘導体及びこれらの抗体薬物複合体
|
|
EP3679036A1
(en)
|
2017-09-08 |
2020-07-15 |
Seattle Genetics, Inc. |
Process for the preparation of tubulysins and intermediates thereof
|
|
SG11202003126VA
(en)
|
2017-10-04 |
2020-05-28 |
Avidity Biosciences Inc |
Nucleic acid-polypeptide compositions and uses thereof
|
|
MX2020005565A
(es)
*
|
2017-11-30 |
2020-08-20 |
Seattle Genetics Inc |
Proceso para la preparacion de compuestos enlazantes de farmaco.
|
|
CN118667812A
(zh)
|
2017-12-06 |
2024-09-20 |
艾维迪提生物科学公司 |
治疗肌萎缩和强直性肌营养不良的组合物和方法
|
|
CN119241554A
(zh)
|
2017-12-15 |
2025-01-03 |
四川科伦博泰生物医药股份有限公司 |
生物活性物偶联物及其制备方法和用途
|
|
CN110090308B
(zh)
*
|
2018-01-30 |
2023-03-24 |
四川科伦博泰生物医药股份有限公司 |
制备偶联物的方法
|
|
JP2021513990A
(ja)
*
|
2018-02-20 |
2021-06-03 |
シージェン インコーポレイテッド |
疎水性アウリスタチンｆ化合物およびそのコンジュゲート
|
|
IL278740B2
(en)
|
2018-06-01 |
2024-01-01 |
Eisai R&D Man Co Ltd |
Methods for using splicing modulators
|
|
IL305431B2
(en)
|
2018-06-01 |
2025-03-01 |
Eisai R&D Man Co Ltd |
Antibody-drug conjugates of splicing modulators and methods of use
|
|
US20210276971A1
(en)
|
2018-06-20 |
2021-09-09 |
The Research Foundation For The State University Of New York |
Triazamacrocycle-derived chelator compositions for coordination of imaging and therapy metal ions and methods of using same
|
|
JP2022504745A
(ja)
*
|
2018-10-12 |
2022-01-13 |
ハンジョウ ディーエーシー バイオテック シーオー．，エルティディ． |
２，３－ジアミノスクシニル基を含む共役連結体
|
|
WO2020081493A1
(en)
|
2018-10-16 |
2020-04-23 |
Molecular Templates, Inc. |
Pd-l1 binding proteins
|
|
KR20210102274A
(ko)
|
2018-12-13 |
2021-08-19 |
에자이 알앤드디 매니지먼트 가부시키가이샤 |
헤르복시디엔 항체-약물 접합체 및 사용 방법
|
|
IL319265A
(en)
|
2018-12-21 |
2025-04-01 |
Avidity Biosciences Inc |
Anti-transferrin receptor antibodies and their uses
|
|
JP2022514348A
(ja)
*
|
2018-12-21 |
2022-02-10 |
シージェン インコーポレイテッド |
チオール多重リンカーを有するａｄｃ
|
|
JP2022523333A
(ja)
|
2019-01-30 |
2022-04-22 |
トゥルーバインディング，インコーポレイテッド |
抗ｇａｌ３抗体およびその使用
|
|
CN113412271B
(zh)
|
2019-02-13 |
2024-10-22 |
住友制药株式会社 |
具有半胱氨酸残基的哈米特林衍生物
|
|
US12178879B2
(en)
|
2019-02-13 |
2024-12-31 |
Sumitomo Pharma Co., Ltd. |
Hemiasterlin derivative and antibody-drug conjugate thereof
|
|
CN109824759A
(zh)
*
|
2019-03-08 |
2019-05-31 |
联宁（苏州）生物制药有限公司 |
一种用于抗体药物偶联物的药物-连接子mc-mmaf的制备方法及其中间体
|
|
KR20220019259A
(ko)
|
2019-06-06 |
2022-02-16 |
어비디티 바이오사이언시스 인크. |
Una 아미다이트 및 이의 용도
|
|
JP7592034B2
(ja)
|
2019-06-06 |
2024-11-29 |
アビディティー バイオサイエンシーズ，インク． |
核酸ポリペプチド組成物およびその使用
|
|
WO2021055816A1
(en)
|
2019-09-18 |
2021-03-25 |
Molecular Templates, Inc. |
Pd-l1 binding molecules comprising shiga toxin a subunit scaffolds
|
|
EP4090379A1
(en)
|
2020-01-13 |
2022-11-23 |
Synaffix B.V. |
Via cycloaddition bilaterally functionalized antibodies
|
|
EP4090376A1
(en)
|
2020-01-13 |
2022-11-23 |
Synaffix B.V. |
Via cycloaddition bilaterally functionalized antibodies
|
|
CN115768483A
(zh)
|
2020-01-13 |
2023-03-07 |
西纳福克斯股份有限公司 |
抗体与免疫细胞衔接器的缀合物
|
|
WO2021173612A1
(en)
|
2020-02-26 |
2021-09-02 |
Sorrento Therapeutics, Inc. |
Activatable antigen binding proteins with universal masking moieties
|
|
CN115190882A
(zh)
*
|
2020-03-09 |
2022-10-14 |
西格马-奥尔德里奇有限责任公司 |
通过共同中间体有效制备多拉司他汀和奥里斯他汀类似物
|
|
EP4121063A4
(en)
|
2020-03-19 |
2024-07-03 |
Avidity Biosciences, Inc. |
COMPOSITIONS AND METHODS FOR TREATING FACIO-SCAPULO-HUMERAL MUSCULAR DYSTROPHY
|
|
JP7748962B2
(ja)
|
2020-03-27 |
2025-10-03 |
アビディティー バイオサイエンシーズ，インク． |
筋ジストロフィーを処置するための組成物および方法
|
|
US10987487B1
(en)
|
2020-04-29 |
2021-04-27 |
Cure Medical Llc |
Gripper sleeve for urinary catheter
|
|
US12281166B2
(en)
|
2020-05-26 |
2025-04-22 |
Truebinding, Inc. |
Methods of treating inflammatory diseases by blocking Galectin-3
|
|
CN116096752B
(zh)
|
2020-06-05 |
2025-10-28 |
卫材R&D管理有限公司 |
抗bcma抗体-药物缀合物及其使用方法
|
|
EP4172141A1
(en)
|
2020-06-26 |
2023-05-03 |
Synaffix B.V. |
Methods for the preparation of linker payload constructs
|
|
NL2026400B1
(en)
|
2020-09-02 |
2022-05-04 |
Synaffix Bv |
Methods for the preparation of bioconjugates
|
|
EP4208259A2
(en)
|
2020-09-04 |
2023-07-12 |
NovaRock Biotherapeutics, Ltd. |
Nectin-4 antibodies and uses thereof
|
|
WO2022058395A1
(en)
|
2020-09-15 |
2022-03-24 |
Synaffix B.V. |
Antibody-exatecan conjugates
|
|
NL2026947B1
(en)
|
2020-11-20 |
2022-07-01 |
Synaffix Bv |
Tyrosine-based antibody conjugates
|
|
TW202237166A
(zh)
|
2020-12-23 |
2022-10-01 |
慕尼黑大學 |
增進的cd30靶向抗體藥物共軛體及其用途
|
|
KR20230137295A
(ko)
*
|
2021-01-28 |
2023-10-04 |
난징 챔피언 바이오테크놀로지 컴퍼니 리미티드 |
접합체 및 이의 용도
|
|
US20250262314A1
(en)
|
2021-02-08 |
2025-08-21 |
Synaffix B.V. |
Multifunctional antibodies
|
|
CA3210069A1
(en)
|
2021-03-03 |
2022-09-09 |
Tong Zhu |
Antibody-drug conjugates comprising an anti-bcma antibody
|
|
US20220306700A1
(en)
|
2021-03-17 |
2022-09-29 |
Molecular Templates, Inc. |
Pd-l1 binding proteins comprising shiga toxin a subunit scaffolds and cd8+ t cell antigens
|
|
CN116897149A
(zh)
*
|
2021-03-30 |
2023-10-17 |
上海复旦张江生物医药股份有限公司 |
一种连接基药物偶联物的制备方法及其中间体
|
|
EP4370555A4
(en)
|
2021-07-13 |
2025-11-12 |
Truebinding Inc |
METHODS FOR PREVENTING PROTEIN AGGREGATION
|
|
KR20240055874A
(ko)
|
2021-09-16 |
2024-04-29 |
어비디티 바이오사이언시스 인크. |
안면견갑상완 근이영양증을 치료하는 조성물 및 방법
|
|
JP2024544508A
(ja)
|
2021-11-09 |
2024-12-03 |
トゥルーバインディング，インコーポレイテッド |
心臓血管疾患を治療または阻害する方法
|
|
WO2023122347A2
(en)
|
2021-12-23 |
2023-06-29 |
Mirecule, Inc. |
Compositions for delivery of polynucleotides
|
|
WO2023173026A1
(en)
|
2022-03-10 |
2023-09-14 |
Sorrento Therapeutics, Inc. |
Antibody-drug conjugates and uses thereof
|
|
US12071621B2
(en)
|
2022-04-05 |
2024-08-27 |
Avidity Biosciences, Inc. |
Anti-transferrin receptor antibody-PMO conjugates for inducing DMD exon 44 skipping
|
|
JP2025528052A
(ja)
|
2022-07-29 |
2025-08-26 |
リジェネロン・ファーマシューティカルズ・インコーポレイテッド |
脳及び筋肉へのトランスフェリン受容体（ｔｆｒ）媒介送達のための組成物及び方法
|
|
EP4572798A1
(en)
|
2022-08-15 |
2025-06-25 |
Synaffix B.V. |
Anthracyclins and conjugates thereof
|
|
JP2025537044A
(ja)
|
2022-09-30 |
2025-11-13 |
シャンハイ ドーァ ノボ ファーマテック カンパニー，リミティド |
ベンザゼピン誘導体、それを含む複合体およびその応用
|
|
EP4619438A2
(en)
|
2022-11-14 |
2025-09-24 |
Regeneron Pharmaceuticals, Inc. |
Compositions and methods for fibroblast growth factor receptor 3-mediated delivery to astrocytes
|
|
EP4389152A1
(en)
|
2022-12-23 |
2024-06-26 |
Synaffix B.V. |
Conjugates of pbd prodrugs
|
|
CN116621927B
(zh)
*
|
2023-01-09 |
2024-03-26 |
联宁（苏州）生物制药有限公司 |
带有伊喜替康和C-lock定点偶联基团的抗体偶联中间体、偶联方法及抗体偶联药物
|
|
EP4410313A1
(en)
|
2023-01-31 |
2024-08-07 |
Synaffix B.V. |
Homogeneous antibody-conjugates with high payload loading
|
|
CN120603814A
(zh)
|
2023-02-28 |
2025-09-05 |
四川科伦博泰生物医药股份有限公司 |
一类化学偶联连接子及其用途
|
|
WO2024211235A1
(en)
|
2023-04-05 |
2024-10-10 |
Sorrento Therapeutics, Inc. |
Antibody-drug conjugates and uses thereof
|
|
WO2024211234A1
(en)
|
2023-04-05 |
2024-10-10 |
Sorrento Therapeutics, Inc. |
Antibody-drug conjugates and uses thereof
|
|
WO2024211236A2
(en)
|
2023-04-05 |
2024-10-10 |
Sorrento Therapeutics, Inc. |
Antibody-drug conjugates and uses thereof
|
|
EP4450093A1
(en)
|
2023-04-17 |
2024-10-23 |
Synaffix B.V. |
Cleavable immune cell engagers
|
|
WO2024218164A1
(en)
|
2023-04-17 |
2024-10-24 |
Synaffix B.V. |
Stable 4-isoxazoline conjugates
|
|
US12491257B2
(en)
|
2023-06-27 |
2025-12-09 |
Avidity Biosciences, Inc. |
Compositions and methods of using PRKAG2-targeting antibody-oligonucleotide conjugates
|
|
US12409230B2
(en)
|
2023-06-30 |
2025-09-09 |
Avidity Biosciences, Inc. |
Compositions comprising PLN-targeting anti-transferrin receptor antibody-polynucleotides and methods of use thereof to treat cardiomyopathy
|
|
WO2025027529A1
(en)
|
2023-07-31 |
2025-02-06 |
Advesya |
Anti-il-1rap antibody drug conjugates and methods of use thereof
|
|
TW202530255A
(zh)
|
2023-12-15 |
2025-08-01 |
法商亞維西亞有限公司 |
抗ｉｌ－１ｒａｐ結合結構域及其抗體－藥物偶聯物
|
|
CN117964682A
(zh)
*
|
2024-01-12 |
2024-05-03 |
杭州爱科瑞思生物医药有限公司 |
Dolastatin衍生物及其制备方法和应用
|
|
WO2025238253A1
(en)
|
2024-05-16 |
2025-11-20 |
Synaffix B.V. |
Antibody-oligonucleotide conjugates
|