JP2014061000A5 - - Google Patents
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- JP2014061000A5 JP2014061000A5 JP2013245908A JP2013245908A JP2014061000A5 JP 2014061000 A5 JP2014061000 A5 JP 2014061000A5 JP 2013245908 A JP2013245908 A JP 2013245908A JP 2013245908 A JP2013245908 A JP 2013245908A JP 2014061000 A5 JP2014061000 A5 JP 2014061000A5
- Authority
- JP
- Japan
- Prior art keywords
- antibody
- fragment
- sclerostin
- seq
- assay
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 102000019307 Sclerostin Human genes 0.000 claims 12
- 108050006698 Sclerostin Proteins 0.000 claims 12
- 239000012634 fragment Substances 0.000 claims 12
- 238000000034 method Methods 0.000 claims 9
- 238000003556 assay Methods 0.000 claims 7
- 210000000988 bone and bone Anatomy 0.000 claims 4
- 238000006386 neutralization reaction Methods 0.000 claims 3
- 125000003275 alpha amino acid group Chemical group 0.000 claims 2
- 238000001514 detection method Methods 0.000 claims 2
- 229910052500 inorganic mineral Inorganic materials 0.000 claims 2
- 239000011707 mineral Substances 0.000 claims 2
- 235000008733 Citrus aurantifolia Nutrition 0.000 claims 1
- 238000012286 ELISA Assay Methods 0.000 claims 1
- 102100024952 Protein CBFA2T1 Human genes 0.000 claims 1
- 235000011941 Tilia x europaea Nutrition 0.000 claims 1
- 230000001195 anabolic effect Effects 0.000 claims 1
- 230000037118 bone strength Effects 0.000 claims 1
- 230000002308 calcification Effects 0.000 claims 1
- 238000006243 chemical reaction Methods 0.000 claims 1
- 230000000694 effects Effects 0.000 claims 1
- 239000004571 lime Substances 0.000 claims 1
- 230000011164 ossification Effects 0.000 claims 1
- 210000000963 osteoblast Anatomy 0.000 claims 1
- 238000012216 screening Methods 0.000 claims 1
- 210000002966 serum Anatomy 0.000 claims 1
- 238000002198 surface plasmon resonance spectroscopy Methods 0.000 claims 1
Applications Claiming Priority (10)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US67758305P | 2005-05-03 | 2005-05-03 | |
| US60/677,583 | 2005-05-03 | ||
| US77684706P | 2006-02-24 | 2006-02-24 | |
| US60/776,847 | 2006-02-24 | ||
| US78224406P | 2006-03-13 | 2006-03-13 | |
| US60/782,244 | 2006-03-13 | ||
| US79264506P | 2006-04-17 | 2006-04-17 | |
| US60/792,645 | 2006-04-17 | ||
| US11/411,003 US7592429B2 (en) | 2005-05-03 | 2006-04-25 | Sclerostin-binding antibody |
| US11/411,003 | 2006-04-25 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008510083A Division JP5462484B2 (ja) | 2005-05-03 | 2006-04-28 | スクレロスチン結合作用物質 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014061000A JP2014061000A (ja) | 2014-04-10 |
| JP2014061000A5 true JP2014061000A5 (enExample) | 2014-05-22 |
| JP5789652B2 JP5789652B2 (ja) | 2015-10-07 |
Family
ID=36992590
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008510083A Active JP5462484B2 (ja) | 2005-05-03 | 2006-04-28 | スクレロスチン結合作用物質 |
| JP2013155968A Active JP5409952B2 (ja) | 2005-05-03 | 2013-07-26 | スクレロスチン結合作用物質 |
| JP2013155969A Active JP5391360B2 (ja) | 2005-05-03 | 2013-07-26 | スクレロスチン結合作用物質 |
| JP2013245908A Active JP5789652B2 (ja) | 2005-05-03 | 2013-11-28 | スクレロスチン結合作用物質 |
Family Applications Before (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008510083A Active JP5462484B2 (ja) | 2005-05-03 | 2006-04-28 | スクレロスチン結合作用物質 |
| JP2013155968A Active JP5409952B2 (ja) | 2005-05-03 | 2013-07-26 | スクレロスチン結合作用物質 |
| JP2013155969A Active JP5391360B2 (ja) | 2005-05-03 | 2013-07-26 | スクレロスチン結合作用物質 |
Country Status (42)
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