CY1120414T1 - Αντισωματα που συνδεονται me οχ40 και οι χρησεις τους - Google Patents
Αντισωματα που συνδεονται me οχ40 και οι χρησεις τουςInfo
- Publication number
- CY1120414T1 CY1120414T1 CY20181100726T CY181100726T CY1120414T1 CY 1120414 T1 CY1120414 T1 CY 1120414T1 CY 20181100726 T CY20181100726 T CY 20181100726T CY 181100726 T CY181100726 T CY 181100726T CY 1120414 T1 CY1120414 T1 CY 1120414T1
- Authority
- CY
- Cyprus
- Prior art keywords
- seq
- amino acid
- acid sequence
- heavy chain
- light chain
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2878—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
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- C07K2317/00—Immunoglobulins specific features
- C07K2317/40—Immunoglobulins specific features characterized by post-translational modification
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- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/70578—NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30 CD40 or CD95
Abstract
Η παρούσα εφεύρεση σχετίζεται με αντισώματα ανταγωνιστές ή τμήματα αυτών που συνδέονται με ανθρώπινο ΟΧ40. Περισσότερο συγκεκριμένα, η παρούσα εφεύρεση σχετίζεται με ένα αντίσωμα ανταγωνιστή ή τμήμα αυτού που συνδέεται με ανθρώπινο ΟΧ40 και περιλαμβάνει μια CDR1 βαριάς αλυσίδας που περιλαμβάνει την αλληλουχία αμινοξέων της SEQ ID NO: 1, ή/και μια CDR2 βαριάς αλυσίδας που περιλαμβάνει την αλληλουχία αμινοξέων της SEQ ID NO: 2, ή/και μια CDR3 βαριάς αλυσίδας που περιλαμβάνει την αλληλουχία αμινοξέων της SEQ ID NO: 3· ή/και το οποίο περιλαμβάνει μια CDR1 ελαφριάς αλυσίδας που περιλαμβάνει την αλληλουχία αμινοξέων της SEQ ID NO: 4, ή/και μια CDR2 ελαφριάς αλυσίδας που περιλαμβάνει την αλληλουχία αμινοξέων της SEQ ID NO: ή/και μια CDR3 ελαφριάς αλυσίδας που περιλαμβάνει την αλληλουχία αμινοξέων της SEQ ID NO: 6.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
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US201161506491P | 2011-07-11 | 2011-07-11 | |
PCT/IB2012/053502 WO2013008171A1 (en) | 2011-07-11 | 2012-07-09 | Antibodies that bind to ox40 and their uses |
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Publication Number | Publication Date |
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CY1120414T1 true CY1120414T1 (el) | 2019-07-10 |
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CY20181100726T CY1120414T1 (el) | 2011-07-11 | 2018-07-11 | Αντισωματα που συνδεονται me οχ40 και οι χρησεις τους |
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