JP2012143232A5 - - Google Patents
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- Publication number
- JP2012143232A5 JP2012143232A5 JP2012021947A JP2012021947A JP2012143232A5 JP 2012143232 A5 JP2012143232 A5 JP 2012143232A5 JP 2012021947 A JP2012021947 A JP 2012021947A JP 2012021947 A JP2012021947 A JP 2012021947A JP 2012143232 A5 JP2012143232 A5 JP 2012143232A5
- Authority
- JP
- Japan
- Prior art keywords
- chain variable
- variable region
- seq
- monoclonal antibody
- heavy chain
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000427 antigen Substances 0.000 claims 12
- 102000036639 antigens Human genes 0.000 claims 12
- 108091007433 antigens Proteins 0.000 claims 12
- 239000012634 fragment Substances 0.000 claims 12
- 210000004027 cell Anatomy 0.000 claims 7
- 238000004519 manufacturing process Methods 0.000 claims 4
- 239000004480 active ingredient Substances 0.000 claims 3
- 125000003275 alpha amino acid group Chemical group 0.000 claims 2
- 238000012258 culturing Methods 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 102000040430 polynucleotide Human genes 0.000 claims 2
- 108091033319 polynucleotide Proteins 0.000 claims 2
- 239000002157 polynucleotide Substances 0.000 claims 2
- 229940124597 therapeutic agent Drugs 0.000 claims 2
- 208000023275 Autoimmune disease Diseases 0.000 claims 1
- 101000984199 Homo sapiens Leukocyte immunoglobulin-like receptor subfamily A member 4 Proteins 0.000 claims 1
- 102000006992 Interferon-alpha Human genes 0.000 claims 1
- 108010047761 Interferon-alpha Proteins 0.000 claims 1
- 102000014150 Interferons Human genes 0.000 claims 1
- 108010050904 Interferons Proteins 0.000 claims 1
- 239000003153 chemical reaction reagent Substances 0.000 claims 1
- 210000004544 dc2 Anatomy 0.000 claims 1
- 238000001514 detection method Methods 0.000 claims 1
- 102000047610 human LILRA4 Human genes 0.000 claims 1
- 239000003112 inhibitor Substances 0.000 claims 1
- 229940079322 interferon Drugs 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 201000000596 systemic lupus erythematosus Diseases 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2012021947A JP5420688B2 (ja) | 2005-12-20 | 2012-02-03 | 抗ｉｌｔ７抗体 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2005366465 | 2005-12-20 | ||
| JP2005366465 | 2005-12-20 | ||
| JP2012021947A JP5420688B2 (ja) | 2005-12-20 | 2012-02-03 | 抗ｉｌｔ７抗体 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007551124A Division JP5020828B2 (ja) | 2005-12-20 | 2006-12-20 | 抗ｉｌｔ７抗体 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012143232A JP2012143232A (ja) | 2012-08-02 |
| JP2012143232A5 true JP2012143232A5 (enExample) | 2013-04-25 |
| JP5420688B2 JP5420688B2 (ja) | 2014-02-19 |
Family
ID=38188642
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007551124A Active JP5020828B2 (ja) | 2005-12-20 | 2006-12-20 | 抗ｉｌｔ７抗体 |
| JP2012021947A Active JP5420688B2 (ja) | 2005-12-20 | 2012-02-03 | 抗ｉｌｔ７抗体 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007551124A Active JP5020828B2 (ja) | 2005-12-20 | 2006-12-20 | 抗ｉｌｔ７抗体 |
Country Status (29)
| Country | Link |
|---|---|
| US (6) | US8084585B2 (enExample) |
| EP (4) | EP3441403A1 (enExample) |
| JP (2) | JP5020828B2 (enExample) |
| KR (3) | KR101585532B1 (enExample) |
| CN (5) | CN101379089B (enExample) |
| AU (1) | AU2006328470B2 (enExample) |
| BR (1) | BRPI0620141B1 (enExample) |
| CA (2) | CA2634116C (enExample) |
| CY (3) | CY1114227T1 (enExample) |
| DK (3) | DK2532681T3 (enExample) |
| ES (3) | ES2416716T3 (enExample) |
| HK (1) | HK1218126A1 (enExample) |
| HR (2) | HRP20130494T1 (enExample) |
| HU (1) | HUE039865T2 (enExample) |
| IL (1) | IL192266A (enExample) |
| LT (1) | LT2913343T (enExample) |
| ME (1) | ME02111B (enExample) |
| MX (1) | MX2008007682A (enExample) |
| NZ (3) | NZ569910A (enExample) |
| PL (3) | PL2532681T3 (enExample) |
| PT (3) | PT2532681E (enExample) |
| RS (2) | RS53752B1 (enExample) |
| RU (2) | RU2456298C2 (enExample) |
| SG (2) | SG170749A1 (enExample) |
| SI (3) | SI2532681T1 (enExample) |
| TR (1) | TR201816574T4 (enExample) |
| UA (1) | UA97946C2 (enExample) |
| WO (1) | WO2007072866A1 (enExample) |
| ZA (1) | ZA200805850B (enExample) |
Families Citing this family (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2892724B1 (fr) * | 2005-11-02 | 2008-01-04 | Lab Francais Du Fractionnement | Anticorps cytotoxiques diriges contre des anticorps inhibiteurs du facteur viii. |
| WO2011060076A1 (en) * | 2009-11-10 | 2011-05-19 | Amgen Inc. | Anti-c-mpl antibodies |
| WO2011063237A2 (en) | 2009-11-19 | 2011-05-26 | Oncomed Pharmaceuticals, Inc. | Jagged-binding agents and uses thereof |
| AR080301A1 (es) | 2010-02-24 | 2012-03-28 | Immunogen Inc | Anticuerpos e inmunoconjugados del receptor 1 de folato y sus usos |
| EP3085387A1 (en) | 2010-04-26 | 2016-10-26 | Abraxis BioScience, LLC | Sparc binding antibodies and uses thereof |
| PL2694106T3 (pl) | 2011-04-01 | 2018-06-29 | Immunogen, Inc. | Sposoby zwiększania skuteczności terapii przeciwnowotworowej opartej na receptorze folr1 |
| DK2828292T3 (da) | 2012-03-20 | 2019-01-02 | Biogen Ma Inc | Jcv-neutraliserende antistoffer |
| DK2828284T3 (da) | 2012-03-20 | 2019-06-11 | Biogen Ma Inc | Jcv-neutraliserende antistoffer |
| WO2014022758A1 (en) * | 2012-08-03 | 2014-02-06 | Dana-Farber Cancer Institute, Inc. | Single agent anti-pd-l1 and pd-l2 dual binding antibodies and methods of use |
| KR20150046316A (ko) | 2012-08-31 | 2015-04-29 | 이뮤노젠 아이엔씨 | 엽산 수용체 1의 검출을 위한 진단성 검정 및 키트 |
| PT3038650T (pt) | 2013-08-30 | 2021-08-25 | Immunogen Inc | Anticorpos e ensaios para a deteção do recetor de folato 1 |
| US10035847B2 (en) | 2013-10-02 | 2018-07-31 | The Rockefeller University | Amyloid protofibril antibodies and methods of use thereof |
| CN114292331A (zh) * | 2013-12-24 | 2022-04-08 | 安斯泰来制药株式会社 | 抗人bdca-2抗体、其生产方法、多核苷酸、表达载体、宿主细胞及医药组合物 |
| US20170306046A1 (en) | 2014-11-12 | 2017-10-26 | Siamab Therapeutics, Inc. | Glycan-interacting compounds and methods of use |
| EA035374B1 (ru) * | 2015-03-18 | 2020-06-03 | Сиэтл Дженетикс, Инк. | Антитела против cd48 и их конъюгаты |
| SMT202100092T1 (it) * | 2015-06-29 | 2021-03-15 | Immunogen Inc | Anticorpi anti-cd123 e loro coniugati e derivati |
| JP6880006B2 (ja) | 2015-09-17 | 2021-06-02 | イミュノジェン， インコーポレイテッド | 抗ｆｏｌｒ１免疫複合体を含む治療組み合わせ |
| CN108463248B (zh) | 2015-11-12 | 2022-10-21 | 西雅图基因公司 | 聚糖相互作用化合物及使用方法 |
| EP3377079A1 (en) * | 2015-11-19 | 2018-09-26 | Abbvie Stemcentrx LLC | Novel anti-emr2 antibodies and methods of use |
| EP3407820A4 (en) | 2016-01-26 | 2019-11-06 | Cyberdontics, Inc. | Automated dental treatment system |
| WO2017132486A1 (en) * | 2016-01-27 | 2017-08-03 | Siamab Therapeutics, Inc. | Compositions and methods for targeting cancer stem cells |
| KR20250065434A (ko) * | 2016-03-01 | 2025-05-12 | 이섬 리서치 디벨러프먼트 컴파니 오브 더 히브루 유니버시티 오브 예루살렘 엘티디. | 인간 폴리오바이러스 수용체(ｐｖｒ)에 특이적인 항체 |
| JP6979976B2 (ja) * | 2016-03-10 | 2021-12-15 | ヴィエラ バイオ，インコーポレーテッド | Ｉｌｔ７結合分子及びその使用方法 |
| WO2017176651A1 (en) | 2016-04-04 | 2017-10-12 | True North Therapeutics, Inc. | Anti-complement factor bb antibodies and uses thereof |
| EP3589319A4 (en) | 2017-03-03 | 2021-07-14 | Seagen Inc. | GLYCAN INTERACTING COMPOUNDS AND METHOD OF USE |
| CA3073733A1 (en) * | 2017-08-30 | 2019-03-07 | Phanes Therapeutics, Inc. | Anti-lag-3 antibodies and uses thereof |
| US11192944B2 (en) | 2017-10-11 | 2021-12-07 | Bioverativ Usa Inc. | Methods of inducing complement activity |
| KR102478433B1 (ko) * | 2017-11-17 | 2022-12-15 | 머크 샤프 앤드 돔 엘엘씨 | 이뮤노글로불린-유사 전사체 3 (ilt3)에 대해 특이적인 항체 및 그의 용도 |
| AU2018392717A1 (en) * | 2017-12-20 | 2020-07-09 | Albert Einstein College Of Medicine | Antibodies to Centrin-1, methods of making, and uses thereof |
| US11655295B2 (en) * | 2018-01-18 | 2023-05-23 | Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. | Anti-LAG-3 antibody and use thereof |
| TW202003576A (zh) * | 2018-05-10 | 2020-01-16 | 美商艾博視訊有限公司 | 活化cd40之單株抗體及其用途 |
| MX2020011894A (es) | 2018-05-10 | 2021-03-29 | Cyberdontics Usa Inc | Taladro dental automatizado. |
| CN114555637B (zh) * | 2019-08-12 | 2026-01-06 | 比昂生物制剂公司 | 针对ilt2的抗体及其用途 |
| EP4041392A1 (en) | 2019-10-08 | 2022-08-17 | Nectin Therapeutics Ltd. | Antibodies against the poliovirus receptor (pvr) and uses thereof |
| WO2021113702A1 (en) * | 2019-12-06 | 2021-06-10 | Viela Bio, Inc. | Methods of treatment using ilt7 binding proteins |
| PH12022552558A1 (en) | 2020-04-20 | 2024-04-22 | Genzyme Corp | Humanized anti-complement factor bb antibodies and uses thereof |
| EP4208122B1 (en) | 2020-09-03 | 2026-02-11 | Perceptive Technologies, Inc. | System for directing an automated dental drill |
| AU2022270101A1 (en) | 2021-05-04 | 2023-10-05 | Viela Bio, Inc. | Methods of treatment of autoimmune disorders using ilt7 binding proteins |
| JP2025526370A (ja) | 2022-07-27 | 2025-08-13 | ビエラ バイオ インコーポレイテッド | 免疫グロブリン様転写物７（ｉｌｔ７）結合タンパク質を含む製剤 |
| CN115819604B (zh) * | 2022-09-09 | 2025-04-15 | 季华实验室 | 抗双链dna抗体、核苷酸片段、磁珠及提取外周血游离dna的方法 |
| EP4680344A1 (en) * | 2023-03-16 | 2026-01-21 | Inmagene Pte. Ltd. | Ilt7-targeting antibodies and uses thereof |
| WO2024229470A1 (en) | 2023-05-04 | 2024-11-07 | Perceptive Technologies, Inc. | Robotic dental system and method of preparing for a robotic dental procedure |
| CN116948032B (zh) * | 2023-09-19 | 2023-12-12 | 汇智生物技术(苏州)有限公司 | 人源cd4单克隆抗体及其制备方法和应用 |
| WO2025118871A1 (zh) * | 2023-12-05 | 2025-06-12 | 苏州普乐康医药科技有限公司 | 一种抗bdca-2抗体及其制备方法和应用 |
| WO2026002175A1 (zh) * | 2024-06-27 | 2026-01-02 | 无锡徕特康生物科技有限公司 | 靶向ilt7和cd89的髓细胞衔接子抗体及其用途 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA952797B (en) * | 1994-04-12 | 1996-10-07 | Res Dev Foundation | Method of treating auto-immune diseases using type one interferons |
| US6107090A (en) * | 1996-05-06 | 2000-08-22 | Cornell Research Foundation, Inc. | Treatment and diagnosis of prostate cancer with antibodies to extracellur PSMA domains |
| EP1156823B1 (en) * | 1999-02-12 | 2008-10-29 | The Scripps Research Institute | Methods for treatment of tumors and metastases using a combination of anti-angiogenic and immuno therapies |
| PL356836A1 (en) * | 2000-02-10 | 2004-07-12 | Abbott Laboratories | Antibodies that bind human interleukin-18 and methods of making and using |
| US6897067B2 (en) * | 2000-11-03 | 2005-05-24 | Regents Of The University Of Michigan | Surface transfection and expression procedure |
| US20040241167A1 (en) * | 2001-06-25 | 2004-12-02 | Nicole Suciu-Foca | Ilt3 and ilt4-related compositons and methods |
| AU2002318944A1 (en) | 2001-08-01 | 2003-02-17 | Coley Pharmaceutical Gmbh | Methods and compositions relating to plasmacytoid dendritic cells |
| PL369953A1 (en) * | 2001-10-13 | 2005-05-02 | Asterion Limited | Glycosylphosphatidylinositol containing polypeptides |
| NZ536475A (en) * | 2002-05-24 | 2008-06-30 | Schering Corp | Neutralizing human anti-igfr antibody |
| AU2003252328A1 (en) | 2002-08-01 | 2004-02-23 | Ginkgo Biomedical Research Institute Co., Ltd. | Method of detecting mouse interferon-producing cells |
| AU2003289716A1 (en) * | 2002-09-12 | 2004-04-30 | Incyte Corporation | Molecules for diagnostics and therapeutics |
| EP1664762A4 (en) | 2003-09-03 | 2008-08-13 | Us Gov Health & Human Serv | METHOD OF IDENTIFYING AND DIAGNOSIS OF, AND VIEWING, SURVIVAL IN LYMPHOMA |
| GB0417487D0 (en) | 2004-08-05 | 2004-09-08 | Novartis Ag | Organic compound |
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2006
- 2006-12-20 HU HUE14186905A patent/HUE039865T2/hu unknown
- 2006-12-20 SI SI200631864T patent/SI2532681T1/sl unknown
- 2006-12-20 SI SI200632299T patent/SI2913343T1/sl unknown
- 2006-12-20 EP EP18187761.4A patent/EP3441403A1/en not_active Withdrawn
- 2006-12-20 CA CA2634116A patent/CA2634116C/en not_active Expired - Fee Related
- 2006-12-20 PT PT121685861T patent/PT2532681E/pt unknown
- 2006-12-20 CN CN200680053131XA patent/CN101379089B/zh active Active
- 2006-12-20 RS RS20140678A patent/RS53752B1/sr unknown
- 2006-12-20 NZ NZ569910A patent/NZ569910A/en not_active IP Right Cessation
- 2006-12-20 SG SG201102016-1A patent/SG170749A1/en unknown
- 2006-12-20 SI SI200631608T patent/SI1964852T1/sl unknown
- 2006-12-20 JP JP2007551124A patent/JP5020828B2/ja active Active
- 2006-12-20 KR KR1020147004977A patent/KR101585532B1/ko active Active
- 2006-12-20 KR KR1020087017667A patent/KR101526934B1/ko active Active
- 2006-12-20 CN CN201911002539.XA patent/CN110776566B/zh active Active
- 2006-12-20 MX MX2008007682A patent/MX2008007682A/es active IP Right Grant
- 2006-12-20 CN CN201510296327.2A patent/CN105111311B/zh not_active Expired - Fee Related
- 2006-12-20 ME MEP-2014-157A patent/ME02111B/me unknown
- 2006-12-20 EP EP12168586.1A patent/EP2532681B1/en active Active
- 2006-12-20 CN CN2013102707794A patent/CN103360492A/zh active Pending
- 2006-12-20 SG SG10201602095PA patent/SG10201602095PA/en unknown
- 2006-12-20 CA CA2994756A patent/CA2994756C/en active Active
- 2006-12-20 DK DK12168586.1T patent/DK2532681T3/en active
- 2006-12-20 US US12/064,957 patent/US8084585B2/en active Active
- 2006-12-20 NZ NZ616992A patent/NZ616992A/en unknown
- 2006-12-20 PT PT14186905T patent/PT2913343T/pt unknown
- 2006-12-20 PT PT68429455T patent/PT1964852E/pt unknown
- 2006-12-20 PL PL12168586T patent/PL2532681T3/pl unknown
- 2006-12-20 EP EP06842945.5A patent/EP1964852B1/en active Active
- 2006-12-20 TR TR2018/16574T patent/TR201816574T4/tr unknown
- 2006-12-20 ES ES06842945T patent/ES2416716T3/es active Active
- 2006-12-20 CN CN202510875177.4A patent/CN120718150A/zh active Pending
- 2006-12-20 WO PCT/JP2006/325391 patent/WO2007072866A1/ja not_active Ceased
- 2006-12-20 BR BRPI0620141-5A patent/BRPI0620141B1/pt active IP Right Grant
- 2006-12-20 ES ES14186905T patent/ES2699428T3/es active Active
- 2006-12-20 DK DK14186905.7T patent/DK2913343T3/en active
- 2006-12-20 AU AU2006328470A patent/AU2006328470B2/en not_active Ceased
- 2006-12-20 EP EP14186905.7A patent/EP2913343B1/en active Active
- 2006-12-20 PL PL14186905T patent/PL2913343T3/pl unknown
- 2006-12-20 UA UAA200809418A patent/UA97946C2/ru unknown
- 2006-12-20 RS RS20130256A patent/RS52860B/sr unknown
- 2006-12-20 DK DK06842945.5T patent/DK1964852T3/da active
- 2006-12-20 KR KR1020157004466A patent/KR101624587B1/ko active Active
- 2006-12-20 ES ES12168586.1T patent/ES2526079T3/es active Active
- 2006-12-20 HR HRP20130494TT patent/HRP20130494T1/hr unknown
- 2006-12-20 PL PL06842945T patent/PL1964852T3/pl unknown
- 2006-12-20 LT LTEP14186905.7T patent/LT2913343T/lt unknown
- 2006-12-20 NZ NZ599683A patent/NZ599683A/xx not_active IP Right Cessation
- 2006-12-20 RU RU2008129715/10A patent/RU2456298C2/ru active
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2008
- 2008-06-18 IL IL192266A patent/IL192266A/en active IP Right Grant
- 2008-07-04 ZA ZA200805850A patent/ZA200805850B/xx unknown
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2011
- 2011-11-22 US US13/302,291 patent/US8470992B2/en active Active
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2012
- 2012-02-03 JP JP2012021947A patent/JP5420688B2/ja active Active
- 2012-03-28 RU RU2012112046/10A patent/RU2599450C2/ru active
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2013
- 2013-06-07 US US13/912,335 patent/US20130259872A1/en not_active Abandoned
- 2013-07-02 CY CY20131100538T patent/CY1114227T1/el unknown
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2014
- 2014-12-16 HR HRP20141226TT patent/HRP20141226T1/hr unknown
- 2014-12-17 CY CY20141101048T patent/CY1116031T1/el unknown
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2015
- 2015-12-16 US US14/971,303 patent/US20160130343A1/en not_active Abandoned
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2016
- 2016-05-30 HK HK16106102.4A patent/HK1218126A1/zh unknown
- 2016-10-31 US US15/339,080 patent/US20170204179A1/en not_active Abandoned
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2018
- 2018-11-07 CY CY20181101167T patent/CY1121294T1/el unknown
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2020
- 2020-02-24 US US16/799,441 patent/US20200339682A1/en active Pending