|
GB812366A
(en)
|
1955-08-18 |
1959-04-22 |
Wellcome Found |
Improvements in and relating to derivatives of pyrimidine and the preparation thereof
|
|
GB937725A
(en)
|
1960-05-11 |
1963-09-25 |
Ciba Ltd |
Pyrazolo[3:4-d]pyrimidines
|
|
US3657744A
(en)
|
1970-05-08 |
1972-04-25 |
Univ Minnesota |
Method for fixing prosthetic implants in a living body
|
|
DE2139107A1
(de)
*
|
1971-08-04 |
1973-02-15 |
Merck Patent Gmbh |
Heterocyclisch substituierte adenosinverbindungen
|
|
IT1153216B
(it)
|
1981-10-16 |
1987-01-14 |
Schering Ag |
Procedimento per la preparazione di composti cianoeterociclici
|
|
DE3244594A1
(de)
|
1982-12-02 |
1984-06-07 |
Hoechst Ag, 6230 Frankfurt |
1-phenylisochinolinderivate und verfahren zu ihrer herstellung, diese verbindung enthaltende pharmazeutische praeparate und deren anwendung
|
|
DE3406533A1
(de)
|
1984-02-23 |
1985-08-29 |
Boehringer Mannheim Gmbh, 6800 Mannheim |
Verwendung von adenosin-derivaten als antiallergica und arzneimittel, die diese enthalten
|
|
US5310731A
(en)
|
1984-06-28 |
1994-05-10 |
Whitby Research, Inc. |
N-6 substituted-5'-(N-substitutedcarboxamido)adenosines as cardiac vasodilators and antihypertensive agents
|
|
US4795627A
(en)
|
1984-10-18 |
1989-01-03 |
University Of Pittsburgh |
Tritium labelled N-mustard type compounds and a process for their production
|
|
US4656159A
(en)
|
1984-10-31 |
1987-04-07 |
Georgetown University |
Galactose-C-6 nitrogen mustard compounds and their uses
|
|
JPS61109797A
(ja)
|
1984-11-01 |
1986-05-28 |
Yuki Gosei Yakuhin Kogyo Kk |
標識化ヌクレオチドおよび標識化ポリヌクレオチド
|
|
US4733665C2
(en)
|
1985-11-07 |
2002-01-29 |
Expandable Grafts Partnership |
Expandable intraluminal graft and method and apparatus for implanting an expandable intraluminal graft
|
|
US5023252A
(en)
|
1985-12-04 |
1991-06-11 |
Conrex Pharmaceutical Corporation |
Transdermal and trans-membrane delivery of drugs
|
|
US5350395A
(en)
|
1986-04-15 |
1994-09-27 |
Yock Paul G |
Angioplasty apparatus facilitating rapid exchanges
|
|
US5061273A
(en)
|
1989-06-01 |
1991-10-29 |
Yock Paul G |
Angioplasty apparatus facilitating rapid exchanges
|
|
US5040548A
(en)
|
1989-06-01 |
1991-08-20 |
Yock Paul G |
Angioplasty mehtod
|
|
US4748982A
(en)
|
1987-01-06 |
1988-06-07 |
Advanced Cardiovascular Systems, Inc. |
Reinforced balloon dilatation catheter with slitted exchange sleeve and method
|
|
US4992445A
(en)
|
1987-06-12 |
1991-02-12 |
American Cyanamid Co. |
Transdermal delivery of pharmaceuticals
|
|
US5001139A
(en)
|
1987-06-12 |
1991-03-19 |
American Cyanamid Company |
Enchancers for the transdermal flux of nivadipine
|
|
WO1990003370A1
(en)
|
1988-09-28 |
1990-04-05 |
Microprobe Corporation |
DERIVATIVES OF PYRAZOLO[3,4-d]PYRIMIDINE
|
|
CA1322628C
(en)
|
1988-10-04 |
1993-10-05 |
Richard A. Schatz |
Expandable intraluminal graft
|
|
GB8827305D0
(en)
|
1988-11-23 |
1988-12-29 |
British Bio Technology |
Compounds
|
|
US5442039A
(en)
|
1989-07-17 |
1995-08-15 |
The Dow Chemical Company |
Mesogenic polycyanates and thermosets thereof
|
|
US5428125A
(en)
|
1989-07-17 |
1995-06-27 |
The Dow Chemical Company |
Mesogenic polycyanates and thermosets thereof
|
|
US5292331A
(en)
|
1989-08-24 |
1994-03-08 |
Applied Vascular Engineering, Inc. |
Endovascular support device
|
|
US6344053B1
(en)
|
1993-12-22 |
2002-02-05 |
Medtronic Ave, Inc. |
Endovascular support device and method
|
|
US5674278A
(en)
|
1989-08-24 |
1997-10-07 |
Arterial Vascular Engineering, Inc. |
Endovascular support device
|
|
US5674998A
(en)
|
1989-09-15 |
1997-10-07 |
Gensia Inc. |
C-4' modified adenosine kinase inhibitors
|
|
US5763597A
(en)
|
1989-09-15 |
1998-06-09 |
Metabasis Therapeutics, Inc. |
Orally active adenosine kinase inhibitors
|
|
US5721356A
(en)
|
1989-09-15 |
1998-02-24 |
Gensia, Inc. |
Orally active adenosine kinase inhibitors
|
|
US5646128A
(en)
|
1989-09-15 |
1997-07-08 |
Gensia, Inc. |
Methods for treating adenosine kinase related conditions
|
|
US5763596A
(en)
|
1989-09-15 |
1998-06-09 |
Metabasis Therapeutics, Inc. |
C-4' modified adenosine kinase inhibitors
|
|
US5795977A
(en)
|
1989-09-15 |
1998-08-18 |
Metabasis Therapeutics, Inc. |
Water soluble adenosine kinase inhibitors
|
|
GB9009542D0
(en)
|
1990-04-27 |
1990-06-20 |
Beecham Group Plc |
Novel compounds
|
|
GB9113137D0
(en)
|
1990-07-13 |
1991-08-07 |
Ici Plc |
Thioxo heterocycles
|
|
US5563257A
(en)
|
1990-08-20 |
1996-10-08 |
Boehringer Mannheim Gmbh |
Phospholipid derivatives of nucleosides
|
|
DE4026265A1
(de)
|
1990-08-20 |
1992-02-27 |
Boehringer Mannheim Gmbh |
Neue phospholipid-derivate von nucleosiden, deren herstellung sowie deren verwendung als antivirale arzneimittel
|
|
SG80526A1
(en)
|
1990-09-25 |
2001-05-22 |
Rhone Poulenc Rorer Int |
Compounds having antihypertensive and anti- ischemic properies
|
|
US5652366A
(en)
|
1990-09-25 |
1997-07-29 |
Rhone-Poulenc Rorer Pharmaceuticals Inc. |
DI (1R)-(-)camphosulfonic acid) salt, preparation thereof and use thereof
|
|
US5561134A
(en)
|
1990-09-25 |
1996-10-01 |
Rhone-Poulenc Rorer Pharmaceuticals Inc. |
Compounds having antihypertensive, cardioprotective, anti-ischemic and antilipolytic properties
|
|
GB9103839D0
(en)
|
1991-02-23 |
1991-04-10 |
Smithkline Beecham Plc |
Pharmaceuticals
|
|
US5916891A
(en)
|
1992-01-13 |
1999-06-29 |
Smithkline Beecham Corporation |
Pyrimidinyl imidazoles
|
|
IL104369A0
(en)
|
1992-01-13 |
1993-05-13 |
Smithkline Beecham Corp |
Novel compounds and compositions
|
|
DE4204031A1
(de)
|
1992-02-12 |
1993-08-19 |
Boehringer Mannheim Gmbh |
Neue lipidphosphonsaeure-nucleosid-konjugate sowie deren verwendung als antivirale arzneimittel
|
|
DE4204032A1
(de)
|
1992-02-12 |
1993-08-19 |
Boehringer Mannheim Gmbh |
Neue liponucleotide, deren herstellunmg sowie deren verwendung als antivirale arzneimittel
|
|
WO1993018035A1
(en)
|
1992-03-04 |
1993-09-16 |
Abbott Laboratories |
Angiotensin ii receptor antagonists
|
|
JP2737518B2
(ja)
|
1992-03-16 |
1998-04-08 |
富士通株式会社 |
赤外線検知器の冷却構造
|
|
US5294612A
(en)
|
1992-03-30 |
1994-03-15 |
Sterling Winthrop Inc. |
6-heterocyclyl pyrazolo [3,4-d]pyrimidin-4-ones and compositions and method of use thereof
|
|
EP0637963B1
(en)
|
1992-04-07 |
2004-08-04 |
The Regents of the University of Michigan |
Cd28 pathway immunoregulation
|
|
GB9208135D0
(en)
|
1992-04-13 |
1992-05-27 |
Ludwig Inst Cancer Res |
Polypeptides having kinase activity,their preparation and use
|
|
DE69333955D1
(de)
|
1992-04-24 |
2006-02-02 |
Stanford Res Inst Int |
Targeting homologer sequenzen in eukaryotenzellen
|
|
EP0672325B2
(en)
|
1992-06-19 |
2008-08-27 |
Honeywell Inc. |
Infrared camera with thermoelectric temperature stabilization
|
|
US6057305A
(en)
|
1992-08-05 |
2000-05-02 |
Institute Of Organic Chemistry And Biochemistry Of The Academy Of Sciences Of The Czech Republic |
Antiretroviral enantiomeric nucleotide analogs
|
|
TW444018B
(en)
|
1992-12-17 |
2001-07-01 |
Pfizer |
Pyrazolopyrimidines
|
|
US5455258A
(en)
|
1993-01-06 |
1995-10-03 |
Ciba-Geigy Corporation |
Arylsulfonamido-substituted hydroxamic acids
|
|
IL108523A0
(en)
|
1993-02-03 |
1994-05-30 |
Gensia Inc |
Pharmaceutical compositions containing adenosine kinase inhibitors for preventing or treating conditions involving inflammatory responses and pain
|
|
AU673055B2
(en)
|
1993-02-03 |
1996-10-24 |
Gensia, Inc. |
Adenosine kinase inhibitors comprising lyxofuranosyl derivatives
|
|
GB9308957D0
(en)
|
1993-04-30 |
1993-06-16 |
Cancer Res Campaign Tech |
Novel produgs
|
|
DK0700430T3
(da)
|
1993-06-04 |
2005-08-15 |
Us Navy |
Fremgangsmåder til selektivt af stimulere proliferation af T-celler
|
|
US5504103A
(en)
|
1993-08-25 |
1996-04-02 |
Eli Lilly And Company |
Inhibition of phosphatidylinositol 3-kinase with 17 β-hydroxywortmannin and analogs thereof
|
|
US5525503A
(en)
|
1993-09-28 |
1996-06-11 |
Dana-Farber Cancer Institute, Inc. |
Signal transduction via CD28
|
|
WO1995012588A1
(en)
|
1993-11-05 |
1995-05-11 |
Biochem Pharma Inc. |
Antineoplastic heteronaphthoquinones
|
|
US5654307A
(en)
|
1994-01-25 |
1997-08-05 |
Warner-Lambert Company |
Bicyclic compounds capable of inhibiting tyrosine kinases of the epidermal growth factor receptor family
|
|
IL112249A
(en)
|
1994-01-25 |
2001-11-25 |
Warner Lambert Co |
Pharmaceutical compositions containing di and tricyclic pyrimidine derivatives for inhibiting tyrosine kinases of the epidermal growth factor receptor family and some new such compounds
|
|
US6632789B1
(en)
|
1994-04-29 |
2003-10-14 |
The United States Of America As Represented By The Secretary Of The Navy |
Methods for modulating T cell responses by manipulating intracellular signal transduction
|
|
DE4418690A1
(de)
|
1994-05-28 |
1996-01-11 |
Boehringer Mannheim Gmbh |
Neue Lipidester von Nucleosid-Monophosphaten und deren Verwendung als immunsuppressive Arzneimittel
|
|
US6323201B1
(en)
|
1994-12-29 |
2001-11-27 |
The Regents Of The University Of California |
Compounds for inhibition of ceramide-mediated signal transduction
|
|
US5863949A
(en)
|
1995-03-08 |
1999-01-26 |
Pfizer Inc |
Arylsulfonylamino hydroxamic acid derivatives
|
|
US6312894B1
(en)
|
1995-04-03 |
2001-11-06 |
Epoch Pharmaceuticals, Inc. |
Hybridization and mismatch discrimination using oligonucleotides conjugated to minor groove binders
|
|
AU711592B2
(en)
|
1995-04-03 |
1999-10-14 |
Novartis Ag |
Pyrazole derivatives and processes for the preparation thereof
|
|
DK0821671T3
(da)
|
1995-04-20 |
2001-04-23 |
Pfizer |
Arylsulfonylhydroxamsyrederivater som MMP- og TNF-inhibitorer
|
|
US5977061A
(en)
|
1995-04-21 |
1999-11-02 |
Institute Of Organic Chemistry And Biochemistry Of The Academy Of Sciences Of The Czech Republic |
N6 - substituted nucleotide analagues and their use
|
|
JPH08295667A
(ja)
|
1995-04-27 |
1996-11-12 |
Takeda Chem Ind Ltd |
複素環化合物、その製造法および剤
|
|
WO1996037777A1
(en)
|
1995-05-23 |
1996-11-28 |
Nelson Randall W |
Mass spectrometric immunoassay
|
|
US5593997A
(en)
|
1995-05-23 |
1997-01-14 |
Pfizer Inc. |
4-aminopyrazolo(3-,4-D)pyrimidine and 4-aminopyrazolo-(3,4-D)pyridine tyrosine kinase inhibitors
|
|
US6403599B1
(en)
|
1995-11-08 |
2002-06-11 |
Pfizer Inc |
Corticotropin releasing factor antagonists
|
|
WO1996040256A1
(en)
|
1995-06-07 |
1996-12-19 |
G.D. Searle & Co. |
Method to treat cardiofibrosis with a combination of an angiotensin ii antagonist and spironolactone
|
|
US5665721A
(en)
|
1995-06-07 |
1997-09-09 |
Abbott Laboratories |
Heterocyclic substituted cyclopentane compounds
|
|
IL122246A
(en)
|
1995-06-07 |
2004-06-01 |
Searle & Co |
Combination of spironolactone and angiotensin II antagonist for the treatment of heart failure
|
|
KR100618466B1
(ko)
|
1995-06-07 |
2006-12-13 |
지.디. 썰 엘엘씨 |
울혈성심마비의치료를위한에폭시-스테로이드계알도스테론길항제및앤지오탠신ii길항제복합요법
|
|
US5763885A
(en)
|
1995-12-19 |
1998-06-09 |
Loral Infrared & Imaging Systems, Inc. |
Method and apparatus for thermal gradient stabilization of microbolometer focal plane arrays
|
|
JPH09143163A
(ja)
|
1995-11-29 |
1997-06-03 |
Fuji Photo Film Co Ltd |
含窒素ヘテロ芳香族アミド類の製造方法
|
|
ES2183905T3
(es)
|
1995-12-20 |
2003-04-01 |
Hoffmann La Roche |
Inhibidores de metaloproteasa de matriz.
|
|
US5747235A
(en)
|
1996-01-26 |
1998-05-05 |
Eastman Kodak Company |
Silver halide light sensitive emulsion layer having enhanced photographic sensitivity
|
|
CH690773A5
(de)
|
1996-02-01 |
2001-01-15 |
Novartis Ag |
Pyrrolo(2,3-d)pyrimide und ihre Verwendung.
|
|
DE19603576A1
(de)
|
1996-02-01 |
1997-08-07 |
Bayer Ag |
Acylierte 4-Amino und 4-Hydrazinopyrimidine
|
|
US5914488A
(en)
|
1996-03-05 |
1999-06-22 |
Mitsubishi Denki Kabushiki Kaisha |
Infrared detector
|
|
GB9611460D0
(en)
|
1996-06-01 |
1996-08-07 |
Ludwig Inst Cancer Res |
Novel lipid kinase
|
|
BR9711805A
(pt)
|
1996-06-20 |
2002-01-15 |
Regents The Univesity Of Texas |
Compostos e métodos para providenciar preparações farmacologicamente ativas e uso dos mesmos
|
|
HUP9903014A3
(en)
|
1996-07-18 |
2000-08-28 |
Pfizer |
Phosphinate derivatives having matrix metalloprotease inhibitor effect and medicaments containing the same
|
|
US6153609A
(en)
|
1996-08-23 |
2000-11-28 |
Pfizer Inc |
Arylsulfonylamino hydroxamic acid derivatives
|
|
US5994358A
(en)
|
1996-10-23 |
1999-11-30 |
Zymogenetics, Inc. |
Compositions and methods for treating bone deficit conditions
|
|
US6251901B1
(en)
|
1996-10-23 |
2001-06-26 |
Zymogenetics, Inc. |
Compositions and methods for treating bone deficit conditions
|
|
US5919808A
(en)
|
1996-10-23 |
1999-07-06 |
Zymogenetics, Inc. |
Compositions and methods for treating bone deficit conditions
|
|
US6342514B1
(en)
|
1996-10-23 |
2002-01-29 |
Zymogenetics, Inc. |
Compositions and methods for treating bone deficit conditions
|
|
US6153631A
(en)
|
1996-10-23 |
2000-11-28 |
Zymogenetics, Inc. |
Compositions and methods for treating bone deficit conditions
|
|
US5965573A
(en)
|
1996-10-23 |
1999-10-12 |
Zymogenetics, Inc. |
Compositions and methods for treating bone deficit conditions
|
|
US5990169A
(en)
|
1996-10-23 |
1999-11-23 |
Zymogenetics, Inc. |
Compositions and methods for treating bone deficit conditions
|
|
US5922753A
(en)
|
1996-10-23 |
1999-07-13 |
Zymogenetics, Inc. |
Methods for treating bone deficit conditions with benzothiazole
|
|
US5948776A
(en)
|
1996-10-23 |
1999-09-07 |
Zymogenetic, Inc. |
Compositions and methods for treating bone deficit conditions
|
|
US5858753A
(en)
|
1996-11-25 |
1999-01-12 |
Icos Corporation |
Lipid kinase
|
|
JP4094066B2
(ja)
|
1996-12-06 |
2008-06-04 |
バーテックス ファーマシューティカルズ インコーポレイテッド |
インターロイキン−１β変換酵素のインヒビター
|
|
US6093737A
(en)
|
1996-12-30 |
2000-07-25 |
Merck & Co., Inc. |
Inhibitors of farnesyl-protein transferase
|
|
AU5131998A
(en)
|
1997-01-06 |
1998-08-03 |
Pfizer Inc. |
Cyclic sulfone derivatives
|
|
JPH10206995A
(ja)
|
1997-01-21 |
1998-08-07 |
Konica Corp |
ハロゲン化銀写真感光材料
|
|
ES2202796T3
(es)
|
1997-02-03 |
2004-04-01 |
Pfizer Products Inc. |
Derivados de acidos arilsulfonilaminohidroxamicos.
|
|
WO1998035048A2
(en)
|
1997-02-07 |
1998-08-13 |
Princeton University |
Engineered protein kinases which can utilize modified nucleotide triphosphate substrates
|
|
JP2000507975A
(ja)
|
1997-02-07 |
2000-06-27 |
ファイザー・インク |
Ｎ−ヒドロキシ−β−スルホニルプロピオンアミド誘導体類及びそれらのマトリックスメタロプロテイナーゼ阻害薬としての使用
|
|
BR9807678A
(pt)
|
1997-02-11 |
2000-02-15 |
Pfizer |
Derivados de ácidos arilsulfonil-hidroxâmicos
|
|
US7863444B2
(en)
|
1997-03-19 |
2011-01-04 |
Abbott Laboratories |
4-aminopyrrolopyrimidines as kinase inhibitors
|
|
ATE242245T1
(de)
|
1997-03-19 |
2003-06-15 |
Basf Ag |
Pyrrolo(2,3-d)pyrimidine und ihre verwendung als tyrosinkinase-inhibitoren
|
|
WO1998052611A1
(en)
|
1997-05-23 |
1998-11-26 |
Nippon Shinyaku Co., Ltd. |
Medicinal composition for prevention or treatment of hepatopathy
|
|
US6207679B1
(en)
|
1997-06-19 |
2001-03-27 |
Sepracor, Inc. |
Antimicrobial agents uses and compositions related thereto
|
|
WO1999018077A1
(en)
|
1997-10-02 |
1999-04-15 |
Eisai Co., Ltd. |
Fused pyridine derivatives
|
|
US6649631B1
(en)
|
1997-10-23 |
2003-11-18 |
The Board Of Regents Of The University Of Texas System |
Compositions and methods for treating bone deficit conditions
|
|
WO1999024432A1
(fr)
|
1997-11-12 |
1999-05-20 |
Mitsubishi Chemical Corporation |
Derives de purine et medicament les renfermant en tant qu'ingredient actif
|
|
GB9725782D0
(en)
|
1997-12-05 |
1998-02-04 |
Pfizer Ltd |
Therapeutic agents
|
|
US6191170B1
(en)
|
1998-01-13 |
2001-02-20 |
Tularik Inc. |
Benzenesulfonamides and benzamides as therapeutic agents
|
|
GB9801690D0
(en)
|
1998-01-27 |
1998-03-25 |
Pfizer Ltd |
Therapeutic agents
|
|
US6127121A
(en)
|
1998-04-03 |
2000-10-03 |
Epoch Pharmaceuticals, Inc. |
Oligonucleotides containing pyrazolo[3,4-D]pyrimidines for hybridization and mismatch discrimination
|
|
US7715989B2
(en)
|
1998-04-03 |
2010-05-11 |
Elitech Holding B.V. |
Systems and methods for predicting oligonucleotide melting temperature (TmS)
|
|
PA8469501A1
(es)
|
1998-04-10 |
2000-09-29 |
Pfizer Prod Inc |
Hidroxamidas del acido (4-arilsulfonilamino)-tetrahidropiran-4-carboxilico
|
|
PA8469401A1
(es)
|
1998-04-10 |
2000-05-24 |
Pfizer Prod Inc |
Derivados biciclicos del acido hidroxamico
|
|
JP2000072773A
(ja)
|
1998-08-28 |
2000-03-07 |
Zeria Pharmaceut Co Ltd |
プリン誘導体
|
|
JP2002527359A
(ja)
|
1998-09-18 |
2002-08-27 |
ビーエーエスエフ アクチェンゲゼルシャフト |
キナーゼインヒビターとしての４−アミノピロリピリミジン
|
|
AU779008C
(en)
|
1999-01-11 |
2005-06-30 |
Princeton University |
High affinity inhibitors for target validation and uses thereof
|
|
CZ27399A3
(cs)
|
1999-01-26 |
2000-08-16 |
Ústav Experimentální Botaniky Av Čr |
Substituované dusíkaté heterocyklické deriváty, způsob jejich přípravy, tyto deriváty pro použití jako léčiva, farmaceutická kompozice a kombinovaný farmaceutický přípravek tyto deriváty obsahující a použití těchto derivátů pro výrobu léčiv
|
|
EP1040831A3
(en)
|
1999-04-02 |
2003-05-02 |
Pfizer Products Inc. |
Use of corticotropin releasing factor (CRF) antagonists to prevent sudden death
|
|
SE515856C2
(sv)
|
1999-05-19 |
2001-10-22 |
Ericsson Telefon Ab L M |
Bärare för elektronikkomponenter
|
|
HK1046402A1
(zh)
|
1999-06-03 |
2003-01-10 |
Basf Aktiengesellschaft |
Benzothiazinone和benzoxazinone化合物
|
|
US6387894B1
(en)
|
1999-06-11 |
2002-05-14 |
Pfizer Inc. |
Use of CRF antagonists and renin-angiotensin system inhibitors
|
|
PE20010306A1
(es)
|
1999-07-02 |
2001-03-29 |
Agouron Pharma |
Compuestos de indazol y composiciones farmaceuticas que los contienen utiles para la inhibicion de proteina kinasa
|
|
TWI262914B
(en)
|
1999-07-02 |
2006-10-01 |
Agouron Pharma |
Compounds and pharmaceutical compositions for inhibiting protein kinases
|
|
GB9919588D0
(en)
|
1999-08-18 |
1999-10-20 |
Hoechst Schering Agrevo Gmbh |
Fungicidal compounds
|
|
AU7080500A
(en)
|
1999-08-27 |
2001-03-26 |
Chemocentryx, Inc. |
Compounds and methods for modulating cxcr3 function
|
|
EP1216234B1
(en)
|
1999-09-16 |
2004-12-29 |
Curis, Inc. |
Mediators of hedgehog signaling pathways, compositions and uses related thereto
|
|
US6921763B2
(en)
|
1999-09-17 |
2005-07-26 |
Abbott Laboratories |
Pyrazolopyrimidines as therapeutic agents
|
|
IL148718A0
(en)
|
1999-09-17 |
2002-09-12 |
Abbott Gmbh & Co Kg |
Pyrazolopyrimidines as therapeutic agents
|
|
US6506769B2
(en)
|
1999-10-06 |
2003-01-14 |
Boehringer Ingelheim Pharmaceuticals, Inc. |
Heterocyclic compounds useful as inhibitors of tyrosine kinases
|
|
ES2225231T3
(es)
|
1999-10-06 |
2005-03-16 |
Boehringer Ingelheim Pharmaceuticals Inc. |
Compuestos heterociclicos, utiles como inhibidores de tirosina quinasas.
|
|
US6472153B1
(en)
|
1999-10-26 |
2002-10-29 |
Epoch Biosciences, Inc. |
Hybridization-triggered fluorescent detection of nucleic acids
|
|
US6660845B1
(en)
|
1999-11-23 |
2003-12-09 |
Epoch Biosciences, Inc. |
Non-aggregating, non-quenching oligomers comprising nucleotide analogues; methods of synthesis and use thereof
|
|
GB0002032D0
(en)
|
2000-01-28 |
2000-03-22 |
Zeneca Ltd |
Chemical compounds
|
|
US7217722B2
(en)
|
2000-02-01 |
2007-05-15 |
Kirin Beer Kabushiki Kaisha |
Nitrogen-containing compounds having kinase inhibitory activity and drugs containing the same
|
|
US6613798B1
(en)
|
2000-03-30 |
2003-09-02 |
Curis, Inc. |
Small organic molecule regulators of cell proliferation
|
|
US7115653B2
(en)
|
2000-03-30 |
2006-10-03 |
Curis, Inc. |
Small organic molecule regulators of cell proliferation
|
|
US20020127625A1
(en)
|
2000-03-31 |
2002-09-12 |
Forskarpatent Is Syd Ab |
Methods of diagnosing immune related diseases
|
|
MXPA02010618A
(es)
|
2000-04-25 |
2004-05-05 |
Icos Corp |
Inhibidores de fosfatidilinositol 3-quinasa delta.
|
|
US6667300B2
(en)
|
2000-04-25 |
2003-12-23 |
Icos Corporation |
Inhibitors of human phosphatidylinositol 3-kinase delta
|
|
US6777439B2
(en)
|
2000-05-30 |
2004-08-17 |
Advanced Research & Technology Institute, Inc. |
Compositions and methods for identifying agents which modulate PTEN function and PI-3 kinase pathways
|
|
KR20030011371A
(ko)
|
2000-06-27 |
2003-02-07 |
진랩스 테크놀러지스, 인크. |
항세균, 항진균 또는 항암 활성을 갖는 신규 화합물
|
|
US6534691B2
(en)
|
2000-07-18 |
2003-03-18 |
E. I. Du Pont De Nemours And Company |
Manufacturing process for α-olefins
|
|
US6811979B2
(en)
|
2000-10-11 |
2004-11-02 |
Applera Corporation |
Fluorescent nucleobase conjugates having anionic linkers
|
|
AU2002213467A1
(en)
|
2000-10-11 |
2002-04-22 |
Chemocentryx, Inc. |
Modulation of ccr4 function
|
|
JP2002131859A
(ja)
|
2000-10-19 |
2002-05-09 |
Konica Corp |
撮影用赤外感光性ハロゲン化銀写真感光材料及び赤外感光性ハロゲン化銀乳剤
|
|
US6890747B2
(en)
|
2000-10-23 |
2005-05-10 |
Warner-Lambert Company |
Phosphoinositide 3-kinases
|
|
US6964967B2
(en)
|
2000-12-11 |
2005-11-15 |
Amgen, Inc. |
Substituted pyrido[2,3-d]pyrimidines and methods for their use
|
|
TWI312779B
(enExample)
|
2000-12-28 |
2009-08-01 |
Daiichi Seiyaku Co |
|
|
US7105499B2
(en)
|
2001-01-22 |
2006-09-12 |
Merck & Co., Inc. |
Nucleoside derivatives as inhibitors of RNA-dependent RNA viral polymerase
|
|
DZ3487A1
(fr)
|
2001-01-22 |
2002-07-25 |
Merck Sharp & Dohme |
Derives de nucleoside comme inhibiteurs de l'arn polymerase virale d'arn-dependant
|
|
GB0102239D0
(en)
|
2001-01-29 |
2001-03-14 |
Cancer Res Ventures Ltd |
Methods of chemical synthisis
|
|
MXPA03008560A
(es)
|
2001-03-22 |
2004-06-30 |
Abbot Gmbh & Co Kg |
Pirazolopirimidinas como agentes terapeuticos.
|
|
US7250569B2
(en)
|
2001-04-26 |
2007-07-31 |
New York University School Of Medicine |
Method for dissolving nanostructural materials
|
|
EP1397350B1
(en)
|
2001-05-08 |
2007-02-28 |
Kudos Pharmaceuticals Limited |
Isoquinolinone derivatives as parp inhibitors
|
|
US7144903B2
(en)
|
2001-05-23 |
2006-12-05 |
Amgen Inc. |
CCR4 antagonists
|
|
US20030236198A1
(en)
|
2001-06-13 |
2003-12-25 |
Genesoft, Inc. |
Antipathogenic benzamide compounds
|
|
WO2002100832A1
(en)
|
2001-06-13 |
2002-12-19 |
Genesoft Pharmaceuticals, Inc. |
Isoquinoline compounds having antiinfective activity
|
|
JP2005505508A
(ja)
|
2001-06-13 |
2005-02-24 |
ジーンソフト ファーマシューティカルズ インコーポレイテッド |
抗感染活性を有するベンゾチオフェン化合物
|
|
EP1463742A4
(en)
|
2001-06-21 |
2006-05-10 |
Ariad Pharma Inc |
NEW PYRAZOLO AND PYRROLO PYRIMIDINES AND THEIR USES
|
|
CA2455181C
(en)
|
2001-08-01 |
2010-04-06 |
Merck & Co., Inc. |
Benzimidazo[4,5-f]isoquinolinone derivatives
|
|
AU2002327422A1
(en)
|
2001-08-03 |
2003-03-18 |
Abbott Laboratories |
Method of identifying inhibitors of lck
|
|
JP4338192B2
(ja)
|
2001-08-10 |
2009-10-07 |
塩野義製薬株式会社 |
抗ウイルス剤
|
|
JP2003073357A
(ja)
|
2001-09-03 |
2003-03-12 |
Mitsubishi Pharma Corp |
アミド化合物を含有するＲｈｏキナーゼ阻害剤
|
|
WO2004043335A2
(en)
|
2001-09-13 |
2004-05-27 |
Genesoft, Inc. |
Methods of treating infection by drug resistant bacteria
|
|
AUPR769501A0
(en)
|
2001-09-14 |
2001-10-11 |
Biomolecular Research Institute Limited |
Cytokine receptor 1
|
|
US7101884B2
(en)
|
2001-09-14 |
2006-09-05 |
Merck & Co., Inc. |
Tyrosine kinase inhibitors
|
|
US7269663B2
(en)
|
2001-09-28 |
2007-09-11 |
Intel Corporation |
Tagging packets with a lookup key to facilitate usage of a unified packet forwarding cache
|
|
TWI330183B
(enExample)
|
2001-10-22 |
2010-09-11 |
Eisai R&D Man Co Ltd |
|
|
BR0213792A
(pt)
|
2001-11-01 |
2004-12-07 |
Janssen Pharmaceutica Nv |
Heteroaril aminas como inibidores de glicogênio sintase cinase 3beta (inibidores de gsk3)
|
|
WO2003048081A2
(en)
|
2001-12-04 |
2003-06-12 |
Bristol-Myers Squibb Company |
Glycinamides as factor xa inhibitors
|
|
JP4085237B2
(ja)
|
2001-12-21 |
2008-05-14 |
日本電気株式会社 |
携帯電話の利用契約システムと通信方法
|
|
US7998986B2
(en)
|
2001-12-21 |
2011-08-16 |
Exelixis Patent Company Llc |
Modulators of LXR
|
|
WO2003057212A1
(en)
|
2001-12-26 |
2003-07-17 |
Genelabs Technologies, Inc. |
Polyamide derivatives possessing antibacterial, antifungal or antitumor activity
|
|
US7414036B2
(en)
|
2002-01-25 |
2008-08-19 |
Muscagen Limited |
Compounds useful as A3 adenosine receptor agonists
|
|
US20040043959A1
(en)
*
|
2002-03-04 |
2004-03-04 |
Bloom Laura A. |
Combination therapies for treating methylthioadenosine phosphorylase deficient cells
|
|
AU2003225933A1
(en)
|
2002-03-22 |
2003-10-13 |
Cellular Genomics, Inc. |
AN IMPROVED FORMULATION OF CERTAIN PYRAZOLO(3,4-d) PYRIMIDINES AS KINASE MODULATORS
|
|
WO2003080582A2
(de)
|
2002-03-26 |
2003-10-02 |
Biofrontera Discovery Gmbh |
Fredericamycin-derivate
|
|
US7166293B2
(en)
|
2002-03-29 |
2007-01-23 |
Carlsbad Technology, Inc. |
Angiogenesis inhibitors
|
|
DE10217046A1
(de)
|
2002-04-17 |
2003-11-06 |
Bioleads Gmbh |
Fredericamycin-Derivate
|
|
JP2005529889A
(ja)
|
2002-04-26 |
2005-10-06 |
ファイザー・プロダクツ・インク |
ピリミジン−２，４，６−トリオンメタロ−プロテイナーゼ阻害剤
|
|
US6794562B2
(en)
|
2002-05-01 |
2004-09-21 |
Stine Seed Farm, Inc. |
Soybean cultivar 0332143
|
|
JP2006506401A
(ja)
|
2002-05-23 |
2006-02-23 |
メルク エンド カムパニー インコーポレーテッド |
有糸分裂キネシン阻害薬
|
|
EP1556357A4
(en)
|
2002-06-14 |
2006-09-13 |
Cytokinetics Inc |
COMPOUNDS, COMPOSITIONS AND METHODS
|
|
AU2003243921B2
(en)
|
2002-06-27 |
2009-05-07 |
Novo Nordisk A/S |
Aryl carbonyl derivatives as therapeutic agents
|
|
US7265111B2
(en)
|
2002-06-27 |
2007-09-04 |
Sanofi-Aventis Deutschland Gmbh |
Adenosine analogues and their use as pharmaceutical agents
|
|
KR101124245B1
(ko)
|
2002-06-27 |
2012-07-02 |
노보 노르디스크 에이/에스 |
치료제로서 아릴 카르보닐 유도체
|
|
DE10230917A1
(de)
|
2002-07-09 |
2004-02-05 |
Bioleads Gmbh |
Fredericamycin-Derivate
|
|
WO2004006906A2
(en)
|
2002-07-15 |
2004-01-22 |
Combinatorx, Incorporated |
Methods for the treatment of neoplasms
|
|
BR0313460A
(pt)
|
2002-08-13 |
2005-07-05 |
Warner Lambert Co |
Derivados de naftaleno como inibidores de metaloproteinase da matriz
|
|
NZ538420A
(en)
|
2002-08-16 |
2007-06-29 |
Kinacia Pty Ltd |
Inhibition of phosphoinositide 3-kinase beta
|
|
AU2003262747A1
(en)
|
2002-08-21 |
2004-03-11 |
Cytokinetics, Inc. |
Compounds, compositions, and methods
|
|
US20030139427A1
(en)
|
2002-08-23 |
2003-07-24 |
Osi Pharmaceuticals Inc. |
Bicyclic pyrimidinyl derivatives and methods of use thereof
|
|
GB0220319D0
(en)
|
2002-09-02 |
2002-10-09 |
Cancer Res Campaign Tech |
Enzyme activated self-immolative nitrogen mustard drugs
|
|
WO2004031177A1
(ja)
|
2002-09-30 |
2004-04-15 |
Banyu Pharmaceutical Co., Ltd. |
２−アミノベンズイミダゾール誘導体
|
|
US20050282814A1
(en)
*
|
2002-10-03 |
2005-12-22 |
Targegen, Inc. |
Vasculostatic agents and methods of use thereof
|
|
JP2004161716A
(ja)
|
2002-11-15 |
2004-06-10 |
Takeda Chem Ind Ltd |
Ｊｎｋ阻害剤
|
|
ES2412273T3
(es)
*
|
2002-11-21 |
2013-07-10 |
Novartis Ag |
Inhibidores de 2-morfolín-4-pirimidinas como inhibidores de fosfotidilinositol (PI) 3-quinasa y su uso en el tratamiento del cáncer.
|
|
ATE496893T1
(de)
|
2002-12-20 |
2011-02-15 |
X Ceptor Therapeutics Inc |
Isochinolinonderivate und deren verwendung als medikamente
|
|
US7365094B2
(en)
|
2002-12-23 |
2008-04-29 |
4Sc Ag |
Compounds as anti-inflammatory, immunomodulatory and anti-proliferatory agents
|
|
US7247736B2
(en)
|
2002-12-23 |
2007-07-24 |
4Sc Ag |
Method of identifying inhibitors of DHODH
|
|
WO2004056746A1
(en)
|
2002-12-23 |
2004-07-08 |
4Sc Ag |
Cycloalkene dicarboxylic acid compounds as anti-inflammatory, immunomodulatory and anti-proliferatory agents
|
|
WO2004078702A1
(en)
|
2003-03-06 |
2004-09-16 |
Dsm Ip Assets B.V. |
PROCESS FOR THE PREPARATION OF AN α-AMINO CARBONYL COMPOUND
|
|
US20040242568A1
(en)
|
2003-03-25 |
2004-12-02 |
Syrrx, Inc. |
Dipeptidyl peptidase inhibitors
|
|
GB0306907D0
(en)
|
2003-03-26 |
2003-04-30 |
Angiogene Pharm Ltd |
Boireductively-activated prodrugs
|
|
WO2004103270A2
(en)
|
2003-04-02 |
2004-12-02 |
Suntory Pharmaceutical Research Laboratories Llc |
Compounds and methods for treatment of thrombosis
|
|
EP1646615B1
(en)
|
2003-06-06 |
2009-08-26 |
Vertex Pharmaceuticals Incorporated |
Pyrimidine derivatives as modulators of atp-binding cassette transporters
|
|
US7429596B2
(en)
|
2003-06-20 |
2008-09-30 |
The Regents Of The University Of California |
1H-pyrrolo [2,3-D] pyrimidine derivatives and methods of use thereof
|
|
EP1680125A1
(en)
|
2003-07-02 |
2006-07-19 |
Warner-Lambert Company LLC |
Combination of an allosteric inhibitor of matrix metalloproteinase-13 and a ligand to an alpha-2-delta receptor
|
|
GB0317951D0
(en)
|
2003-07-31 |
2003-09-03 |
Trigen Ltd |
Compounds
|
|
US7208601B2
(en)
|
2003-08-08 |
2007-04-24 |
Mjalli Adnan M M |
Aryl and heteroaryl compounds, compositions, and methods of use
|
|
US7501538B2
(en)
|
2003-08-08 |
2009-03-10 |
Transtech Pharma, Inc. |
Aryl and heteroaryl compounds, compositions and methods of use
|
|
WO2005016349A1
(en)
|
2003-08-14 |
2005-02-24 |
Icos Corporation |
Methods of inhibiting leukocyte accumulation
|
|
WO2005016348A1
(en)
|
2003-08-14 |
2005-02-24 |
Icos Corporation |
Method of inhibiting immune responses stimulated by an endogenous factor
|
|
US20050124637A1
(en)
|
2003-08-15 |
2005-06-09 |
Irm Llc |
Compounds and compositions as inhibitors of receptor tyrosine kinase activity
|
|
US7390820B2
(en)
|
2003-08-25 |
2008-06-24 |
Amgen Inc. |
Substituted quinolinone derivatives and methods of use
|
|
WO2005044181A2
(en)
|
2003-09-09 |
2005-05-19 |
Temple University-Of The Commonwealth System Of Higher Education |
Protection of tissues and cells from cytotoxic effects of ionizing radiation by abl inhibitors
|
|
GB0322409D0
(en)
|
2003-09-25 |
2003-10-29 |
Astrazeneca Ab |
Quinazoline derivatives
|
|
EP1687002A4
(en)
|
2003-11-10 |
2008-07-23 |
Synta Pharmaceuticals Corp |
CONDENSED HETEROCYCLIC COMPOUNDS
|
|
CA2546192C
(en)
|
2003-11-17 |
2010-04-06 |
Pfizer Products Inc. |
Pyrrolopyrimidine compounds useful in treatment of cancer
|
|
US7449477B2
(en)
|
2003-11-25 |
2008-11-11 |
Eli Lilly And Company |
7-phenyl-isoquinoline-5-sulfonylamino derivatives as inhibitors of akt (protein kinase B)
|
|
JP2007513154A
(ja)
|
2003-12-08 |
2007-05-24 |
サイトキネティクス・インコーポレーテッド |
化合物、組成物及び方法
|
|
WO2005063258A1
(en)
|
2003-12-22 |
2005-07-14 |
Gilead Sciences, Inc. |
Kinase inhibitor phosphonate conjugates
|
|
DE602004025504D1
(de)
|
2003-12-23 |
2010-03-25 |
Novartis Ag |
Bicyclische heterocyclische p-38-kinase-inhibitoren
|
|
CA2552664A1
(en)
|
2004-01-08 |
2005-07-28 |
Michigan State University |
Methods for treating and preventing hypertension and hypertension-related disorders
|
|
US20050214310A1
(en)
|
2004-01-23 |
2005-09-29 |
Seattle Genetics, Inc. |
Melphalan prodrugs
|
|
JP2007520559A
(ja)
|
2004-02-03 |
2007-07-26 |
アボット・ラボラトリーズ |
治療薬としてのアミノベンゾオキサゾール類
|
|
CA2555824C
(en)
|
2004-02-13 |
2011-06-07 |
Banyu Pharmaceutical Co., Ltd. |
Fused-ring 4-oxopyrimidine derivative
|
|
US20050187418A1
(en)
|
2004-02-19 |
2005-08-25 |
Small Brooke L. |
Olefin oligomerization
|
|
EP1720874A4
(en)
|
2004-02-24 |
2010-03-03 |
Bioaxone Therapeutique Inc |
4-SUBSTITUTED PIPERIDINE DERIVATIVES
|
|
CA2557575A1
(en)
|
2004-02-27 |
2005-09-15 |
F. Hoffmann-La Roche Ag |
Fused derivatives of pyrazole
|
|
DE602005014964D1
(de)
|
2004-04-02 |
2009-07-30 |
Osi Pharm Inc |
Mit einem 6,6-bicyclischen ring substituierte heterobicyclische proteinkinaseinhibitoren
|
|
AU2005238386A1
(en)
|
2004-04-30 |
2005-11-10 |
Takeda Pharmaceutical Company Limited |
Heterocyclic amide compound and use thereof as an MMP-13 inhibitor
|
|
DE102004022897A1
(de)
|
2004-05-10 |
2005-12-08 |
Bayer Cropscience Ag |
Azinyl-imidazoazine
|
|
PL1761540T3
(pl)
|
2004-05-13 |
2017-06-30 |
Icos Corporation |
Chinazolinony jako inhibitory ludzkiej kinazy 3-fosfatydyloinozytolu delta
|
|
CA2566436C
(en)
|
2004-05-13 |
2011-05-10 |
Vanderbilt University |
Phosphoinositide 3-kinase delta selective inhibitors for inhibiting angiogenesis
|
|
JP2008500338A
(ja)
|
2004-05-25 |
2008-01-10 |
イコス・コーポレイション |
造血細胞の異常増殖を治療及び／又は予防する方法
|
|
EP1750715A1
(en)
|
2004-06-04 |
2007-02-14 |
Icos Corporation |
Methods for treating mast cell disorders
|
|
DE102004044221A1
(de)
*
|
2004-09-14 |
2006-03-16 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Neue 3-Methyl-7-butinyl-xanthine, deren Herstellung und deren Verwendung als Arzneimittel
|
|
GB0420722D0
(en)
|
2004-09-17 |
2004-10-20 |
Addex Pharmaceuticals Sa |
Novel allosteric modulators
|
|
WO2006038865A1
(en)
|
2004-10-01 |
2006-04-13 |
Betagenon Ab |
Nucleotide derivatives for the treatment of type 2 diabetes and other disorders
|
|
US7622451B2
(en)
|
2004-11-03 |
2009-11-24 |
University Of Kansas |
Novobiocin analogues as neuroprotective agents and in the treatment of autoimmune disorders
|
|
CA2585091C
(en)
|
2004-11-03 |
2016-07-19 |
University Of Kansas |
Novobiocin analogues as anticancer agents
|
|
US8212011B2
(en)
|
2004-11-03 |
2012-07-03 |
University Of Kansas |
Novobiocin analogues
|
|
US8212012B2
(en)
|
2004-11-03 |
2012-07-03 |
University Of Kansas |
Novobiocin analogues having modified sugar moieties
|
|
GB0425035D0
(en)
|
2004-11-12 |
2004-12-15 |
Novartis Ag |
Organic compounds
|
|
US9512125B2
(en)
|
2004-11-19 |
2016-12-06 |
The Regents Of The University Of California |
Substituted pyrazolo[3.4-D] pyrimidines as anti-inflammatory agents
|
|
JP2008520742A
(ja)
|
2004-11-23 |
2008-06-19 |
ピーティーシー セラピューティクス， インコーポレイテッド |
Ｖｅｇｆ産生の阻害に有用なカルバゾール誘導体、カルボリン誘導体およびインドール誘導体
|
|
US20060156485A1
(en)
|
2005-01-14 |
2006-07-20 |
The Procter & Gamble Company |
Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof
|
|
GB0501999D0
(en)
|
2005-02-01 |
2005-03-09 |
Sentinel Oncology Ltd |
Pharmaceutical compounds
|
|
EP1885356A2
(en)
|
2005-02-17 |
2008-02-13 |
Icos Corporation |
Phosphoinositide 3-kinase inhibitors for inhibiting leukocyte accumulation
|
|
WO2006091897A2
(en)
|
2005-02-25 |
2006-08-31 |
Adenosine Therapeutics, Llc |
Derivatives of 8-substituted xanthines
|
|
US20090124654A1
(en)
|
2005-03-01 |
2009-05-14 |
Mjalli Adnan M M |
Aryl and Heteroaryl Compounds, Compositions, Methods of Use
|
|
US7872050B2
(en)
|
2005-03-14 |
2011-01-18 |
Yaupon Therapeutics Inc. |
Stabilized compositions of volatile alkylating agents and methods of using thereof
|
|
WO2006108107A1
(en)
|
2005-04-06 |
2006-10-12 |
Irm Llc |
Diarylamine-containing compounds and compositions, and their use as modulators of steroid hormone nuclear receptors
|
|
KR100781704B1
(ko)
|
2005-04-20 |
2007-12-03 |
에스케이케미칼주식회사 |
피리딘 유도체와 이의 제조방법, 및 이를 포함하는약제조성물
|
|
WO2006114064A2
(en)
|
2005-04-25 |
2006-11-02 |
Institute Of Organic Chemistry And Biochemistry Ofthe Academy Of Sciences Of The Czech Republic |
Use of compounds to enhance processivity of telomerase
|
|
CN100526315C
(zh)
*
|
2005-06-16 |
2009-08-12 |
浙江医药股份有限公司新昌制药厂 |
N2-喹啉或异喹啉取代的嘌呤衍生物及其制备方法和其用途
|
|
MX2007015917A
(es)
|
2005-06-22 |
2008-03-10 |
Chemocentryx Inc |
Compuestos de azaindazol y metodos de uso.
|
|
ATE474829T1
(de)
|
2005-06-27 |
2010-08-15 |
Amgen Inc |
Entzündungshemmende arylnitrilverbindungen
|
|
JP2009505948A
(ja)
|
2005-07-11 |
2009-02-12 |
デブジェン エヌブイ |
キナーゼ阻害剤としてのアミド誘導体
|
|
WO2007006547A1
(en)
|
2005-07-11 |
2007-01-18 |
Devgen N.V. |
Amide derivatives as kinase inhibitors
|
|
US20070017915A1
(en)
|
2005-07-22 |
2007-01-25 |
Weder Donald E |
Collapsible and/or erectable substantially egg-shaped container
|
|
GB0516723D0
(en)
|
2005-08-15 |
2005-09-21 |
Novartis Ag |
Organic compounds
|
|
WO2007025090A2
(en)
|
2005-08-25 |
2007-03-01 |
Kalypsys, Inc. |
Heterobicyclic and - tricyclic inhibitors of mapk/erk kinase
|
|
AU2006283940A1
(en)
|
2005-08-25 |
2007-03-01 |
F. Hoffmann-La Roche Ag |
P38 MAP kinase inhibitors and methods for using the same
|
|
WO2007025534A1
(de)
|
2005-09-01 |
2007-03-08 |
Bioagency Ag |
Fredericamycin-derivate
|
|
JP2009510066A
(ja)
|
2005-09-29 |
2009-03-12 |
ワイス |
血管運動症状（ｖｍｓ）の治療のためのモノアミン再取り込みのモジュレータである１−（１ｈ−インドール−１−イル）−３−（メチルアミノ）−１−フェニルプロパン−２−オール誘導体および関連の化合物
|
|
GB2431156A
(en)
*
|
2005-10-11 |
2007-04-18 |
Piramed Ltd |
1-cyclyl-3-substituted- -benzenes and -azines as inhibitors of phosphatidylinositol 3-kinase
|
|
AU2006316605B2
(en)
|
2005-11-17 |
2012-04-26 |
Osi Pharmaceuticals, Inc. |
Fused bicyclic mTOR inhibitors
|
|
US20090088452A1
(en)
|
2005-11-22 |
2009-04-02 |
Coleman Paul J |
Indole Orexin Receptor Antagonists
|
|
US7572809B2
(en)
*
|
2005-12-19 |
2009-08-11 |
Hoffmann-La Roche Inc. |
Isoquinoline aminopyrazole derivatives
|
|
WO2007075554A2
(en)
|
2005-12-19 |
2007-07-05 |
Osi Pharmaceuticals, Inc. |
Combination of igfr inhibitor and anti-cancer agent
|
|
WO2007079164A2
(en)
|
2005-12-29 |
2007-07-12 |
Abbott Laboratories |
Protein kinase inhibitors
|
|
WO2007089669A2
(en)
|
2006-01-26 |
2007-08-09 |
Wyeth |
Processes for the preparation of compounds which modulate cell proliferation
|
|
CA2645137A1
(en)
|
2006-03-07 |
2007-09-13 |
James F. Blake |
Heterobicyclic pyrazole compounds and methods of use
|
|
HRP20160990T1
(hr)
|
2006-03-24 |
2016-10-07 |
Biogen Hemophilia Inc. |
Pc5 kao enzim obrade faktor ix propeptida
|
|
JP2009531443A
(ja)
|
2006-03-29 |
2009-09-03 |
フォールドアールエックス ファーマシューティカルズ インコーポレーティッド |
α−シヌクレイン毒性の抑制
|
|
KR101499783B1
(ko)
|
2006-04-04 |
2015-03-09 |
더 리젠트스 오브 더 유니이버시티 오브 캘리포니아 |
키나제 길항물질
|
|
WO2007121453A2
(en)
|
2006-04-17 |
2007-10-25 |
The Regents Of The University Of California |
2-hydroxy-1-oxo 1,2 dihydro isoquinoline chelating agents
|
|
PE20080361A1
(es)
|
2006-04-21 |
2008-06-03 |
Novartis Ag |
Compuestos derivados de purina como activadores del receptor de adenosina a2a
|
|
GB0607948D0
(en)
|
2006-04-21 |
2006-05-31 |
Novartis Ag |
Organic compounds
|
|
GB0607950D0
(en)
|
2006-04-21 |
2006-05-31 |
Novartis Ag |
Organic compounds
|
|
WO2007125315A2
(en)
|
2006-04-25 |
2007-11-08 |
Astex Therapeutics Limited |
Pharmaceutical compounds
|
|
US20090082370A1
(en)
|
2006-04-25 |
2009-03-26 |
Neil Thomas Thompson |
Pharmaceutical Combinations of PK Inhibitors and Other Active Agents
|
|
DE102006020327A1
(de)
|
2006-04-27 |
2007-12-27 |
Bayer Healthcare Ag |
Heterocyclisch substituierte, anellierte Pyrazol-Derivate und ihre Verwendung
|
|
EP2029593A1
(en)
|
2006-05-22 |
2009-03-04 |
AstraZeneca AB |
Indole derivatives
|
|
GB0610242D0
(en)
|
2006-05-23 |
2006-07-05 |
Novartis Ag |
Organic compounds
|
|
ATE491428T1
(de)
|
2006-05-24 |
2011-01-15 |
Guardant S R L |
Alkalisiertes lokalanästhetikum im beutel
|
|
GB0610317D0
(en)
|
2006-05-24 |
2006-07-05 |
Medical Res Council |
Antiparasitic compounds and compositions
|
|
EP2079724B1
(en)
|
2006-07-20 |
2010-05-26 |
Amgen Inc. |
Substituted pyridone compounds and methods of use
|
|
AU2007278178A1
(en)
*
|
2006-07-28 |
2008-01-31 |
Novartis Ag |
2,4-substituted quinazolines as lipid kinase inhibitors
|
|
CA2661307C
(en)
|
2006-08-22 |
2016-07-19 |
Technion Research And Development Foundation Ltd. |
Heterocyclic derivatives binding to the peripheral-type benzodiazepine receptor (pbr)
|
|
EP2069325A2
(en)
|
2006-08-24 |
2009-06-17 |
Serenex, Inc. |
Isoquinoline, quinazoline and phthalazine derivatives
|
|
SG174086A1
(en)
*
|
2006-08-30 |
2011-09-29 |
Cellzome Ltd |
Triazole derivatives as kinase inhibitors
|
|
WO2008025755A1
(de)
|
2006-09-01 |
2008-03-06 |
Basf Se |
Verwendung von n-haltigen heterozyklen in dermokosmetika
|
|
CA2974246C
(en)
|
2006-09-01 |
2020-02-25 |
Senhwa Biosciences, Inc. |
Tricyclic heteroaryl compounds and their use as protein modulators
|
|
EP1903044A1
(en)
|
2006-09-14 |
2008-03-26 |
Novartis AG |
Adenosine Derivatives as A2A Receptor Agonists
|
|
JP5306818B2
(ja)
|
2006-10-18 |
2013-10-02 |
武田薬品工業株式会社 |
縮合複素環化合物
|
|
US7772180B2
(en)
|
2006-11-09 |
2010-08-10 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
|
SG178786A1
(en)
|
2006-11-13 |
2012-03-29 |
Lilly Co Eli |
Thienopyrimidinones for treatment of inflammatory disorders and cancers
|
|
WO2008063625A2
(en)
|
2006-11-20 |
2008-05-29 |
Adolor Corporation |
Pyridine compounds and methods of their use
|
|
CN102336752A
(zh)
|
2006-11-20 |
2012-02-01 |
诺瓦提斯公司 |
2-甲基-2-[4-(3-甲基-2-氧代-8-喹啉-3-基-2,3-二氢-咪唑并[4,5-c]喹啉-1-基)-苯基]-丙腈的盐和晶型
|
|
WO2008070507A2
(en)
|
2006-12-06 |
2008-06-12 |
Boehringer Ingelheim International Gmbh |
Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof
|
|
CN101611007A
(zh)
|
2006-12-20 |
2009-12-23 |
先灵公司 |
新颖的jnk抑制剂
|
|
KR20090101278A
(ko)
|
2006-12-22 |
2009-09-24 |
인더스트리얼 리서치 리미티드 |
누클레오시다제 및 포스포릴라제 억제제의 아제티딘 유사체
|
|
EP2124954A2
(en)
|
2007-01-26 |
2009-12-02 |
Irm Llc |
Purine compounds and compositions as kinase inhibitors for the treatment of plasmodium related diseases
|
|
WO2008112715A2
(en)
|
2007-03-12 |
2008-09-18 |
Vm Discovery Inc. |
Novel agents of calcium ion channel modulators
|
|
AU2008231304B2
(en)
|
2007-03-23 |
2011-05-12 |
Amgen Inc. |
Heterocyclic compounds and their uses
|
|
US7705018B2
(en)
|
2007-03-23 |
2010-04-27 |
Amgen Inc. |
Substituted quinolines and their uses in treatment of inflammatory and related conditions
|
|
EP2132207A2
(en)
|
2007-03-23 |
2009-12-16 |
Amgen Inc. |
Heterocyclic compounds and their uses
|
|
US7867983B2
(en)
|
2007-03-29 |
2011-01-11 |
The University Of Connecticut |
Methods to protect skeletal muscle against injury
|
|
KR20100015546A
(ko)
|
2007-04-13 |
2010-02-12 |
사노피-아벤티스 |
Ｎ-아미노인돌의 전이 금속 촉매된 합성
|
|
WO2008125014A1
(fr)
|
2007-04-13 |
2008-10-23 |
Institute Of Pharmacology And Toxicology Academy Of Military Medical Sciences P.L.A. |
Composés d'urée, leurs procédés de préparation et leurs utilisations pharmaceutiques
|
|
JP2010163361A
(ja)
|
2007-04-27 |
2010-07-29 |
Dainippon Sumitomo Pharma Co Ltd |
キノリン誘導体
|
|
US7960353B2
(en)
|
2007-05-10 |
2011-06-14 |
University Of Kansas |
Novobiocin analogues as neuroprotective agents and in the treatment of autoimmune disorders
|
|
US20090214529A9
(en)
|
2007-05-22 |
2009-08-27 |
Taigen Biotechnology Co., Ltd. |
Kinesin inhibitors
|
|
US7928111B2
(en)
|
2007-06-08 |
2011-04-19 |
Senomyx, Inc. |
Compounds including substituted thienopyrimidinone derivatives as ligands for modulating chemosensory receptors
|
|
US9603848B2
(en)
|
2007-06-08 |
2017-03-28 |
Senomyx, Inc. |
Modulation of chemosensory receptors and ligands associated therewith
|
|
WO2008157500A1
(en)
|
2007-06-17 |
2008-12-24 |
Kalypsys, Inc. |
Aminoquinazoline cannabinoid receptor modulators for treatment of disease
|
|
ATE538120T1
(de)
|
2007-06-26 |
2012-01-15 |
Sanofi Sa |
Regioselektive, metallkatalysierte synthese annelierter benzimidazole und azabenzimidazole
|
|
WO2009004621A1
(en)
|
2007-07-02 |
2009-01-08 |
Technion Research & Development Foundation Ltd. |
Compositions, articles and methods comprising tspo ligands for preventing or reducing tobacco-associated damage
|
|
RU2345996C1
(ru)
|
2007-07-17 |
2009-02-10 |
Андрей Александрович Иващенко |
Аннелированные азагетероциклические амиды, включающие пиримидиновый фрагмент, способ их получения и применения
|
|
ES2401557T3
(es)
*
|
2007-08-02 |
2013-04-22 |
Amgen, Inc |
Moduladores de Pl3 cinasas y métodos de uso
|
|
US20090053192A1
(en)
|
2007-08-10 |
2009-02-26 |
Burnham Institute For Medical Research |
Tissue-nonspecific alkaline phosphatase (tnap) activators and uses thereof
|
|
CA2695583A1
(en)
|
2007-08-13 |
2009-02-19 |
Metabasis Therapeutics, Inc. |
Novel activators of glucokinase
|
|
WO2009029617A1
(en)
|
2007-08-27 |
2009-03-05 |
Kalypsys, Inc. |
Diarylamine-substituted quinolones useful as inducible nitric oxide synthase inhibitors
|
|
WO2009044707A1
(ja)
|
2007-10-03 |
2009-04-09 |
Riken |
ニトロトリアゾール誘導体、およびそれを用いる化合物の製造方法
|
|
JP2011500657A
(ja)
|
2007-10-15 |
2011-01-06 |
アストラゼネカ アクチボラグ |
組合せ０５９
|
|
NZ585460A
(en)
|
2007-11-13 |
2013-02-22 |
Icos Corp |
Inhibitors of human phosphatidyl-inositol 3-kinase delta
|
|
CA2708391A1
(en)
|
2007-12-13 |
2009-06-25 |
Sri International |
Ppar-delta ligands and methods of their use
|
|
US8399483B2
(en)
|
2007-12-21 |
2013-03-19 |
Ucb Pharma S.A. |
Quinoxaline and quinoline derivatives as kinase inhibitors
|
|
US7960397B2
(en)
|
2007-12-28 |
2011-06-14 |
Institute Of Experimental Botany, Academy Of Sciences Of The Czech Republic |
6,9-disubstituted purine derivatives and their use as cosmetics and cosmetic compositions
|
|
AU2009204483B2
(en)
|
2008-01-04 |
2014-03-13 |
Intellikine, Llc |
Certain chemical entities, compositions and methods
|
|
US8193182B2
(en)
|
2008-01-04 |
2012-06-05 |
Intellikine, Inc. |
Substituted isoquinolin-1(2H)-ones, and methods of use thereof
|
|
CN101938904A
(zh)
|
2008-01-09 |
2011-01-05 |
PGx健康有限责任公司 |
用a2ar激动剂鞘内治疗神经性疼痛
|
|
EP2259790A1
(en)
|
2008-02-07 |
2010-12-15 |
Gilead Palo Alto, Inc. |
Abca-1 elevating compounds and the use thereof
|
|
EP2244709A4
(en)
|
2008-02-07 |
2012-02-29 |
Synta Pharmaceuticals Corp |
TOPICAL FORMULATIONS FOR THE TREATMENT OF PSORIASIS
|
|
TWI444384B
(zh)
|
2008-02-20 |
2014-07-11 |
Gilead Sciences Inc |
核苷酸類似物及其在治療惡性腫瘤上的用途
|
|
US8993580B2
(en)
|
2008-03-14 |
2015-03-31 |
Intellikine Llc |
Benzothiazole kinase inhibitors and methods of use
|
|
WO2009117157A1
(en)
|
2008-03-20 |
2009-09-24 |
Amgen Inc. |
Aurora kinase modulators and method of use
|
|
CA2721851A1
(en)
|
2008-05-30 |
2009-12-03 |
Genentech, Inc. |
Purine pi3k inhibitor compounds and methods of use
|
|
US20090312406A1
(en)
|
2008-06-12 |
2009-12-17 |
Hsing-Pang Hsieh |
Coumarin compounds and their use for treating viral infection
|
|
US20110224223A1
(en)
|
2008-07-08 |
2011-09-15 |
The Regents Of The University Of California, A California Corporation |
MTOR Modulators and Uses Thereof
|
|
MX2011000216A
(es)
|
2008-07-08 |
2011-03-29 |
Intellikine Inc |
Inhibidores de cinasa y metodos para su uso.
|
|
EP2328897A1
(en)
|
2008-07-16 |
2011-06-08 |
Schering Corporation |
Bicyclic heterocycle derivatives and their use as gpcr modulators
|
|
US8450344B2
(en)
|
2008-07-25 |
2013-05-28 |
Aerie Pharmaceuticals, Inc. |
Beta- and gamma-amino-isoquinoline amide compounds and substituted benzamide compounds
|
|
EP2331525A4
(en)
|
2008-08-11 |
2013-01-02 |
Harvard College |
HALOFUGINONE ANALOGUE FOR INHIBITING TRNA SYNTHETASES AND APPLICATIONS THEREOF
|
|
AU2009298877A1
(en)
|
2008-09-23 |
2010-04-08 |
Georgetown University |
Viral and fungal inhibitors
|
|
WO2010036380A1
(en)
|
2008-09-26 |
2010-04-01 |
Intellikine, Inc. |
Heterocyclic kinase inhibitors
|
|
UY32177A
(es)
*
|
2008-10-16 |
2010-05-31 |
Boehringer Ingelheim Int |
Tratamiento de diabetes en pacientes con control glucémico insuficiente a pesar de la terapia con fármaco, oral o no, antidiabético
|
|
US8476431B2
(en)
|
2008-11-03 |
2013-07-02 |
Itellikine LLC |
Benzoxazole kinase inhibitors and methods of use
|
|
US20110269779A1
(en)
|
2008-11-18 |
2011-11-03 |
Intellikine, Inc. |
Methods and compositions for treatment of ophthalmic conditions
|
|
US20110294803A1
(en)
|
2008-12-04 |
2011-12-01 |
Law Amanda J |
Phosphatidylinositol-3-kinase p110 delta-targeted drugs in the treatment of cns disorders
|
|
CN102256963B
(zh)
|
2008-12-19 |
2014-06-11 |
贝林格尔.英格海姆国际有限公司 |
作为ccr2受体拮抗剂用于治疗炎症、哮喘和copd的环状嘧啶-4-甲酰胺
|
|
WO2010083218A1
(en)
|
2009-01-13 |
2010-07-22 |
Van Andel Research Institute |
Methods of using substituted isoxazolo pyridinones as dissociated glucocorticoids
|
|
US8513284B2
(en)
|
2009-02-13 |
2013-08-20 |
Ucb Pharma, S.A. |
Fused pyridine and pyrazine derivatives as kinase inhibitors
|
|
WO2010129816A2
(en)
|
2009-05-07 |
2010-11-11 |
Intellikine, Inc. |
Heterocyclic compounds and uses thereof
|
|
GB0908957D0
(en)
|
2009-05-22 |
2009-07-01 |
Ucb Pharma Sa |
Therapeutic agents
|
|
CN101602768B
(zh)
|
2009-07-17 |
2012-05-30 |
河南省农科院农副产品加工研究所 |
一种芝麻素和芝麻林素的提纯方法
|
|
US8106146B2
(en)
|
2009-10-06 |
2012-01-31 |
Medtronic, Inc. |
Therapeutic polymers and methods of generation
|
|
ES2520345T3
(es)
|
2009-11-12 |
2014-11-11 |
Ucb Pharma, S.A. |
Derivados de quinolina y quinoxalina en calidad de inhibidores de quinasa
|
|
EP2499144B1
(en)
|
2009-11-12 |
2013-10-23 |
UCB Pharma, S.A. |
Quinoline and quinoxaline derivatives as kinase inhibitors
|
|
WO2011058109A1
(en)
|
2009-11-12 |
2011-05-19 |
Ucb Pharma S.A. |
Fused bicyclic pyrrole and imidazole derivatives as kinase inhibitors
|
|
EP2513109A1
(en)
|
2009-12-18 |
2012-10-24 |
Amgen Inc. |
Heterocyclic compounds and their uses
|
|
AR079529A1
(es)
|
2009-12-18 |
2012-02-01 |
Incyte Corp |
Derivados arilo y heteroarilo sustituidos y fundidos como inhibidores de la pi3k
|
|
NZ600954A
(en)
|
2009-12-22 |
2013-11-29 |
|
Isoindolinone inhibitors of phosphatidylinositol 3-kinase
|
|
JP5951600B2
(ja)
|
2010-05-21 |
2016-07-13 |
インフィニティー ファーマシューティカルズ， インコーポレイテッド |
キナーゼ調節のための、化合物、組成物および方法
|
|
AR082799A1
(es)
|
2010-09-08 |
2013-01-09 |
Ucb Pharma Sa |
Derivados de quinolina y quinoxalina como inhibidores de quinasa
|
|
CA2815445A1
(en)
|
2010-11-04 |
2012-05-10 |
Amgen Inc. |
5 -cyano-4, 6 -diaminopyrimidine or 6 -aminopurine derivatives as pi3k-delta inhibitors
|
|
US8901133B2
(en)
|
2010-11-10 |
2014-12-02 |
Infinity Pharmaceuticals, Inc. |
Heterocyclic compounds and uses thereof
|
|
KR20180080358A
(ko)
|
2011-01-10 |
2018-07-11 |
인피니티 파마슈티칼스, 인코포레이티드 |
이소퀴놀린온 및 이의 고체 형태의 제조 방법
|
|
WO2012148548A1
(en)
|
2011-02-25 |
2012-11-01 |
Takeda Pharmaceutical Company Limited |
N-substituted oxazinopteridines and oxazinopteridinones
|
|
EP2734530A1
(en)
|
2011-07-19 |
2014-05-28 |
Infinity Pharmaceuticals, Inc. |
Heterocyclic compounds and uses thereof
|
|
CN103930422A
(zh)
|
2011-07-19 |
2014-07-16 |
无限药品股份有限公司 |
杂环化合物及其用途
|
|
CN103998442B
(zh)
|
2011-08-29 |
2016-09-14 |
无限药品股份有限公司 |
杂环化合物及其用途
|