|
CA2483923A1
(en)
*
|
2002-05-31 |
2003-12-11 |
Schering Corporation |
Process for preparing xanthine phosphodiesterase v inhibitors and precursors thereof
|
|
GB0215293D0
(en)
|
2002-07-03 |
2002-08-14 |
Rega Foundation |
Viral inhibitors
|
|
MEP59708A
(en)
*
|
2002-08-21 |
2011-05-10 |
Boehringer Ingelheim Pharma |
8-[3-amino-piperidin-1-yl]-xanthines, the production thereof and the use of the same as medicaments
|
|
US7407955B2
(en)
|
2002-08-21 |
2008-08-05 |
Boehringer Ingelheim Pharma Gmbh & Co., Kg |
8-[3-amino-piperidin-1-yl]-xanthines, the preparation thereof and their use as pharmaceutical compositions
|
|
US7569574B2
(en)
|
2002-08-22 |
2009-08-04 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Purine derivatives, the preparation thereof and their use as pharmaceutical compositions
|
|
US7495005B2
(en)
|
2002-08-22 |
2009-02-24 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Xanthine derivatives, their preparation and their use in pharmaceutical compositions
|
|
US7482337B2
(en)
|
2002-11-08 |
2009-01-27 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Xanthine derivatives, the preparation thereof and their use as pharmaceutical compositions
|
|
DE10251927A1
(de)
*
|
2002-11-08 |
2004-05-19 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Neue Xanthinderivate, deren Herstellung und deren Verwendung als Arzneimittel
|
|
DE10254304A1
(de)
|
2002-11-21 |
2004-06-03 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Neue Xanthinderivate, deren Herstellung und deren Verwendung als Arzneimittel
|
|
US20040242568A1
(en)
|
2003-03-25 |
2004-12-02 |
Syrrx, Inc. |
Dipeptidyl peptidase inhibitors
|
|
ATE462432T1
(de)
|
2003-05-05 |
2010-04-15 |
Probiodrug Ag |
Glutaminylcyclase-hemmer
|
|
WO2004103993A1
(en)
|
2003-05-14 |
2004-12-02 |
Syrrx, Inc. |
Dipeptidyl peptidase inhibitors
|
|
US7566707B2
(en)
|
2003-06-18 |
2009-07-28 |
Boehringer Ingelheim International Gmbh |
Imidazopyridazinone and imidazopyridone derivatives, the preparation thereof and their use as pharmaceutical compositions
|
|
EP1506967B1
(en)
|
2003-08-13 |
2007-11-21 |
Takeda Pharmaceutical Company Limited |
Dipeptidyl peptidase inhibitors
|
|
DE10355304A1
(de)
|
2003-11-27 |
2005-06-23 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Neue 8-(Piperazin-1-yl)-und 8-([1,4]Diazepan-1-yl)-xanthine, deren Herstellung und deren Verwendung als Arzneimittel
|
|
JP4970048B2
(ja)
|
2003-12-22 |
2012-07-04 |
カトリーケ・ウニフェルジテイト・ルーベン・カー・イュー・ルーベン・アール・アンド・ディ |
イミダゾ[4,5−c]ピリジン化合物および抗ウイルス治療の方法
|
|
DE10360835A1
(de)
|
2003-12-23 |
2005-07-21 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Bicyclische Imidazolverbindungen, deren Herstellung und deren Verwendung als Arzneimittel
|
|
AU2012202850B2
(en)
*
|
2004-02-18 |
2015-08-20 |
Boehringer Ingelheim International Gmbh |
8-[3-amino-piperidin-1-yl]-xanthine, the production thereof and the use in the form of a DPP inhibitor
|
|
US7501426B2
(en)
|
2004-02-18 |
2009-03-10 |
Boehringer Ingelheim International Gmbh |
8-[3-amino-piperidin-1-yl]-xanthines, their preparation and their use as pharmaceutical compositions
|
|
CA2555050C
(en)
*
|
2004-02-18 |
2017-11-28 |
Boehringer Ingelheim International Gmbh |
8-[3-amino-piperidin-1-yl]-xanthine derivatives, the production thereof and the use in the form of a dpp-iv inhibitor
|
|
DE102004009039A1
(de)
|
2004-02-23 |
2005-09-08 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
8-[3-Amino-piperidin-1-yl]-xanthine, deren Herstellung und Verwendung als Arzneimittel
|
|
US7393847B2
(en)
|
2004-03-13 |
2008-07-01 |
Boehringer Ingleheim International Gmbh |
Imidazopyridazinediones, their preparation and their use as pharmaceutical compositions
|
|
MXPA06010571A
(es)
|
2004-03-15 |
2007-02-16 |
Takeda Pharmaceutical |
Inhibidores de dipeptidil peptidasa.
|
|
US7439370B2
(en)
|
2004-05-10 |
2008-10-21 |
Boehringer Ingelheim International Gmbh |
Imidazole derivatives, their preparation and their use as intermediates for the preparation of pharmaceutical compositions and pesticides
|
|
DE102004030502A1
(de)
|
2004-06-24 |
2006-01-12 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Neue Imidazole und Triazole, deren Herstellung und Verwendung als Arzneimittel
|
|
CN101027303A
(zh)
|
2004-07-27 |
2007-08-29 |
吉里德科学公司 |
咪唑并[4,5-d]嘧啶类、其应用和制备方法
|
|
DE102004043944A1
(de)
|
2004-09-11 |
2006-03-30 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Neue 8-(3-Amino-piperidin-1-yl)-7-(but-2-inyl)-xanthine, deren Herstellung und deren Verwendung als Arzneimittel
|
|
DE102004044221A1
(de)
|
2004-09-14 |
2006-03-16 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Neue 3-Methyl-7-butinyl-xanthine, deren Herstellung und deren Verwendung als Arzneimittel
|
|
AU2012205240B2
(en)
*
|
2004-11-05 |
2015-03-26 |
Boehringer Ingelheim International Gmbh |
Method for producing chiral 8-(3-amino-piperidin-1-yl)-xanthines
|
|
DE102004054054A1
(de)
*
|
2004-11-05 |
2006-05-11 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Verfahren zur Herstellung chiraler 8-(3-Amino-piperidin-1-yl)-xanthine
|
|
DE602005013580D1
(de)
|
2004-12-21 |
2009-05-07 |
Leuven K U Res & Dev |
Imidazoä4,5-cüpyridinverbindung und verfahren zur antiviralen behandlung
|
|
DOP2006000008A
(es)
|
2005-01-10 |
2006-08-31 |
Arena Pharm Inc |
Terapia combinada para el tratamiento de la diabetes y afecciones relacionadas y para el tratamiento de afecciones que mejoran mediante un incremento de la concentración sanguínea de glp-1
|
|
US7772191B2
(en)
|
2005-05-10 |
2010-08-10 |
Boehringer Ingelheim International Gmbh |
Processes for preparing of glucopyranosyl-substituted benzyl-benzene derivatives and intermediates therein
|
|
DE102005035891A1
(de)
|
2005-07-30 |
2007-02-08 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
8-(3-Amino-piperidin-1-yl)-xanthine, deren Herstellung und deren Verwendung als Arzneimittel
|
|
ME02005B
(me)
|
2005-09-14 |
2012-08-31 |
Takeda Pharmaceuticals Co |
Inhibitori dipeptidil peptidaze za lečenje dijabetesa
|
|
CA2622608C
(en)
†
|
2005-09-14 |
2014-08-19 |
Takeda Pharmaceutical Company Limited |
Dipeptidyl peptidase inhibitors for treating diabetes
|
|
CN101360723A
(zh)
|
2005-09-16 |
2009-02-04 |
武田药品工业株式会社 |
制备嘧啶二酮衍生物的方法
|
|
GB0526291D0
(en)
|
2005-12-23 |
2006-02-01 |
Prosidion Ltd |
Therapeutic method
|
|
BRPI0620464A2
(pt)
*
|
2005-12-23 |
2011-11-16 |
Astrazeneca Ab |
composto, composição farmacêutica, uso de um composto, e, método para o tratamento de uma doença
|
|
TW200803855A
(en)
*
|
2006-02-24 |
2008-01-16 |
Kalypsys Inc |
Quinolones useful as inducible nitric oxide synthase inhibitors
|
|
WO2007112347A1
(en)
|
2006-03-28 |
2007-10-04 |
Takeda Pharmaceutical Company Limited |
Dipeptidyl peptidase inhibitors
|
|
PE20071221A1
(es)
|
2006-04-11 |
2007-12-14 |
Arena Pharm Inc |
Agonistas del receptor gpr119 en metodos para aumentar la masa osea y para tratar la osteoporosis y otras afecciones caracterizadas por masa osea baja, y la terapia combinada relacionada a estos agonistas
|
|
MX2008014024A
(es)
|
2006-05-04 |
2008-11-14 |
Boehringer Ingelheim Int |
Formas poliformas.
|
|
PE20110235A1
(es)
*
|
2006-05-04 |
2011-04-14 |
Boehringer Ingelheim Int |
Combinaciones farmaceuticas que comprenden linagliptina y metmorfina
|
|
EP1852108A1
(en)
|
2006-05-04 |
2007-11-07 |
Boehringer Ingelheim Pharma GmbH & Co.KG |
DPP IV inhibitor formulations
|
|
TWI360549B
(en)
|
2006-07-07 |
2012-03-21 |
Gilead Sciences Inc |
Novel pyridazine compound and use thereof
|
|
EP2057160A1
(en)
*
|
2006-08-08 |
2009-05-13 |
Boehringer Ingelheim International GmbH |
Pyrrolo [3, 2 -d]pyrimidines as dpp-iv inhibitors for the treatment of diabetes mellitus
|
|
US8324383B2
(en)
|
2006-09-13 |
2012-12-04 |
Takeda Pharmaceutical Company Limited |
Methods of making polymorphs of benzoate salt of 2-[[6-[(3R)-3-amino-1-piperidinyl]-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidinyl]methyl]-benzonitrile
|
|
JP5379692B2
(ja)
|
2006-11-09 |
2013-12-25 |
プロビオドルグ エージー |
潰瘍、癌及び他の疾患の治療のためのグルタミニルシクラーゼの阻害薬としての3−ヒドロキシ−1,5−ジヒドロ−ピロール−2−オン誘導体
|
|
TW200838536A
(en)
|
2006-11-29 |
2008-10-01 |
Takeda Pharmaceutical |
Polymorphs of succinate salt of 2-[6-(3-amino-piperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-ylmethy]-4-fluor-benzonitrile and methods of use therefor
|
|
EP2091948B1
(en)
|
2006-11-30 |
2012-04-18 |
Probiodrug AG |
Novel inhibitors of glutaminyl cyclase
|
|
US8093236B2
(en)
|
2007-03-13 |
2012-01-10 |
Takeda Pharmaceuticals Company Limited |
Weekly administration of dipeptidyl peptidase inhibitors
|
|
US9656991B2
(en)
|
2007-04-18 |
2017-05-23 |
Probiodrug Ag |
Inhibitors of glutaminyl cyclase
|
|
UA99466C2
(en)
|
2007-07-06 |
2012-08-27 |
Гилиад Сайенсиз, Инк. |
Crystalline pyridazine compound
|
|
PE20090597A1
(es)
*
|
2007-08-16 |
2009-06-06 |
Boehringer Ingelheim Int |
Composicion farmaceutica que comprende un derivado de pirazol-o-glucosido
|
|
CL2008002427A1
(es)
|
2007-08-16 |
2009-09-11 |
Boehringer Ingelheim Int |
Composicion farmaceutica que comprende 1-cloro-4-(b-d-glucopiranos-1-il)-2-[4-((s)-tetrahidrofurano-3-iloxi)bencil]-benceno combinado con 1-[(4-metilquinazolin-2-il)metil]-3-metil-7-(2-butin-1-il)-8-(3-(r)-aminopiperidin-1-il)xantina; y su uso para tratar diabetes mellitus tipo 2.
|
|
EP3542801A1
(en)
*
|
2007-08-17 |
2019-09-25 |
Boehringer Ingelheim International GmbH |
Purin derivatives for use in the treatment of fap-related diseases
|
|
PE20140960A1
(es)
|
2008-04-03 |
2014-08-15 |
Boehringer Ingelheim Int |
Formulaciones que comprenden un inhibidor de dpp4
|
|
EP2108960A1
(en)
|
2008-04-07 |
2009-10-14 |
Arena Pharmaceuticals, Inc. |
Methods of using A G protein-coupled receptor to identify peptide YY (PYY) secretagogues and compounds useful in the treatment of conditons modulated by PYY
|
|
PE20100156A1
(es)
*
|
2008-06-03 |
2010-02-23 |
Boehringer Ingelheim Int |
Tratamiento de nafld
|
|
UY32030A
(es)
*
|
2008-08-06 |
2010-03-26 |
Boehringer Ingelheim Int |
"tratamiento para diabetes en pacientes inapropiados para terapia con metformina"
|
|
KR20200118243A
(ko)
|
2008-08-06 |
2020-10-14 |
베링거 인겔하임 인터내셔날 게엠베하 |
메트포르민 요법이 부적합한 환자에서의 당뇨병 치료
|
|
CN103816158A
(zh)
*
|
2008-08-15 |
2014-05-28 |
勃林格殷格翰国际有限公司 |
用于治疗fab-相关疾病的嘌呤衍生物
|
|
CN102149407A
(zh)
|
2008-09-10 |
2011-08-10 |
贝林格尔.英格海姆国际有限公司 |
治疗糖尿病和相关病症的组合疗法
|
|
US20200155558A1
(en)
|
2018-11-20 |
2020-05-21 |
Boehringer Ingelheim International Gmbh |
Treatment for diabetes in patients with insufficient glycemic control despite therapy with an oral antidiabetic drug
|
|
UY32177A
(es)
*
|
2008-10-16 |
2010-05-31 |
Boehringer Ingelheim Int |
Tratamiento de diabetes en pacientes con control glucémico insuficiente a pesar de la terapia con fármaco, oral o no, antidiabético
|
|
CN107011345A
(zh)
*
|
2008-12-23 |
2017-08-04 |
勃林格殷格翰国际有限公司 |
有机化合物的盐形式
|
|
TW201036975A
(en)
*
|
2009-01-07 |
2010-10-16 |
Boehringer Ingelheim Int |
Treatment for diabetes in patients with inadequate glycemic control despite metformin therapy
|
|
TWI466672B
(zh)
*
|
2009-01-29 |
2015-01-01 |
Boehringer Ingelheim Int |
小兒科病人糖尿病之治療
|
|
AU2010212823B2
(en)
|
2009-02-13 |
2016-01-28 |
Boehringer Ingelheim International Gmbh |
Antidiabetic medications comprising a DPP-4 inhibitor (linagliptin) optionally in combination with other antidiabetics
|
|
EP4684831A3
(en)
|
2009-02-13 |
2026-03-11 |
Boehringer Ingelheim International GmbH |
Sglt2 inhibitor for improving glycemic control
|
|
UY32427A
(es)
*
|
2009-02-13 |
2010-09-30 |
Boheringer Ingelheim Internat Gmbh |
Composicion farmaceutica, forma farmaceutica, procedimiento para su preparacion, metodos de tratamiento y usos de la misma
|
|
HUE050287T2
(hu)
|
2009-02-13 |
2020-11-30 |
Boehringer Ingelheim Int |
SGLT2-inhibitort, DPP-IV-inhibitort és adott esetben egy további antidiabetikus hatóanyagot tartalmazó gyógyászati készítmény és alkalmazásai
|
|
AR077642A1
(es)
|
2009-07-09 |
2011-09-14 |
Arena Pharm Inc |
Moduladores del metabolismo y el tratamiento de trastornos relacionados con el mismo
|
|
BR112012008346B1
(pt)
|
2009-09-11 |
2021-12-21 |
Vivoryon Therapeutics N.V. |
Derivados heterocíclicos, seu processo de preparação, e composição farmacêutica
|
|
BR112012007085B8
(pt)
|
2009-09-30 |
2021-05-25 |
Boehringer Ingelheim Int |
processos para a preparação de derivados de benzil-benzeno substituídos com glicopiranosila
|
|
NZ598318A
(en)
|
2009-09-30 |
2014-02-28 |
Boehringer Ingelheim Int |
Method for the preparation of a crystalline form of 1-chloro-4- (beta-d-glucopyranos-1-yl)-2-(4-((s)-tetrahydrofuran-3-yloxy)benzyl)benzene
|
|
UY32919A
(es)
|
2009-10-02 |
2011-04-29 |
Boehringer Ingelheim Int |
Composición farmacéutica, forma de dosificación farmacéutica, procedimiento para su preparación, mé todos para su tratamiento y sus usos
|
|
ES2942185T3
(es)
|
2009-10-02 |
2023-05-30 |
Boehringer Ingelheim Int |
Composiciones farmacéuticas que comprenden BI-1356 y metformina
|
|
EP2504002B1
(en)
|
2009-11-27 |
2019-10-09 |
Boehringer Ingelheim International GmbH |
Treatment of genotyped diabetic patients with dpp-iv inhibitors such as linagliptin
|
|
WO2011107530A2
(en)
|
2010-03-03 |
2011-09-09 |
Probiodrug Ag |
Novel inhibitors
|
|
DK2545047T3
(da)
|
2010-03-10 |
2014-07-28 |
Probiodrug Ag |
Heterocycliske inhibitorer af glutaminylcyclase (QC, EC 2.3.2.5)
|
|
WO2011113947A1
(en)
|
2010-03-18 |
2011-09-22 |
Boehringer Ingelheim International Gmbh |
Combination of a gpr119 agonist and the dpp-iv inhibitor linagliptin for use in the treatment of diabetes and related conditions
|
|
WO2011127051A1
(en)
|
2010-04-06 |
2011-10-13 |
Arena Pharmaceuticals, Inc. |
Modulators of the gpr119 receptor and the treatment of disorders related thereto
|
|
EP2560953B1
(en)
|
2010-04-21 |
2016-01-06 |
Probiodrug AG |
Inhibitors of glutaminyl cyclase
|
|
KR101927068B1
(ko)
*
|
2010-05-05 |
2018-12-10 |
베링거 인겔하임 인터내셔날 게엠베하 |
체중 감소 치료에 후속하는 dpp-4 억제제에 의한 순차적 병용 요법
|
|
CN102883711A
(zh)
|
2010-05-05 |
2013-01-16 |
贝林格尔.英格海姆国际有限公司 |
包含吡格列酮和利格列汀的药物组合物
|
|
KR20200028498A
(ko)
*
|
2010-06-24 |
2020-03-16 |
베링거 인겔하임 인터내셔날 게엠베하 |
당뇨병 요법
|
|
SG188548A1
(en)
|
2010-09-22 |
2013-04-30 |
Arena Pharm Inc |
Modulators of the gpr119 receptor and the treatment of disorders related thereto
|
|
MX371198B
(es)
*
|
2010-11-15 |
2020-01-22 |
Boehringer Ingelheim Int |
Terapia antidiabetica vasoprotectora y cardioprotectora.
|
|
AR083878A1
(es)
*
|
2010-11-15 |
2013-03-27 |
Boehringer Ingelheim Int |
Terapia antidiabetica vasoprotectora y cardioprotectora, linagliptina, metodo de tratamiento
|
|
US20130035281A1
(en)
|
2011-02-09 |
2013-02-07 |
Boehringer Ingelheim International Gmbh |
Pharmaceutical composition, methods for treating and uses thereof
|
|
AR085689A1
(es)
|
2011-03-07 |
2013-10-23 |
Boehringer Ingelheim Int |
Composiciones farmaceuticas de metformina, linagliptina y un inhibidor de sglt-2
|
|
WO2012123563A1
(en)
|
2011-03-16 |
2012-09-20 |
Probiodrug Ag |
Benz imidazole derivatives as inhibitors of glutaminyl cyclase
|
|
WO2012135570A1
(en)
|
2011-04-01 |
2012-10-04 |
Arena Pharmaceuticals, Inc. |
Modulators of the gpr119 receptor and the treatment of disorders related thereto
|
|
US20140066369A1
(en)
|
2011-04-19 |
2014-03-06 |
Arena Pharmaceuticals, Inc. |
Modulators Of The GPR119 Receptor And The Treatment Of Disorders Related Thereto
|
|
US20140051714A1
(en)
|
2011-04-22 |
2014-02-20 |
Arena Pharmaceuticals, Inc. |
Modulators Of The GPR119 Receptor And The Treatment Of Disorders Related Thereto
|
|
US20140038889A1
(en)
|
2011-04-22 |
2014-02-06 |
Arena Pharmaceuticals, Inc. |
Modulators Of The GPR119 Receptor And The Treatment Of Disorders Related Thereto
|
|
EP2707368B1
(en)
|
2011-05-10 |
2016-02-03 |
Sandoz AG |
Polymorph of linagliptin benzoate
|
|
WO2012170702A1
(en)
|
2011-06-08 |
2012-12-13 |
Arena Pharmaceuticals, Inc. |
Modulators of the gpr119 receptor and the treatment of disorders related thereto
|
|
HUE061596T2
(hu)
*
|
2011-07-15 |
2023-07-28 |
Boehringer Ingelheim Int |
Szubsztituált dimer kinazolin származék, annak elõállítása és alkalmazása az I. és II. típusú cukorbetegség kezelésére szolgáló gyógyszerkészítményekben
|
|
WO2013055910A1
(en)
|
2011-10-12 |
2013-04-18 |
Arena Pharmaceuticals, Inc. |
Modulators of the gpr119 receptor and the treatment of disorders related thereto
|
|
US20130123282A1
(en)
|
2011-11-16 |
2013-05-16 |
Leonid Metsger |
Solid state forms of linagliptin
|
|
US20130172244A1
(en)
|
2011-12-29 |
2013-07-04 |
Thomas Klein |
Subcutaneous therapeutic use of dpp-4 inhibitor
|
|
CN103254192B
(zh)
*
|
2012-02-15 |
2015-12-02 |
上海医药工业研究院 |
黄嘌呤类化合物、其盐、中间体、制备方法及应用
|
|
CN103254193B
(zh)
*
|
2012-02-15 |
2015-04-22 |
上海医药工业研究院 |
黄嘌呤类化合物中间体及其制备方法
|
|
US9555001B2
(en)
|
2012-03-07 |
2017-01-31 |
Boehringer Ingelheim International Gmbh |
Pharmaceutical composition and uses thereof
|
|
WO2013171756A1
(en)
*
|
2012-03-12 |
2013-11-21 |
Cadila Healthcare Limited |
Amorphous form of linagliptin and process for preparation thereof
|
|
US9192617B2
(en)
|
2012-03-20 |
2015-11-24 |
Boehringer Ingelheim International Gmbh |
Pharmaceutical composition, methods for treating and uses thereof
|
|
CN103373999B
(zh)
*
|
2012-04-28 |
2016-01-13 |
上海医药工业研究院 |
嘌呤类化合物、中间体、制备方法及其应用
|
|
US20130303462A1
(en)
*
|
2012-05-14 |
2013-11-14 |
Boehringer Ingelheim International Gmbh |
Use of a dpp-4 inhibitor in podocytes related disorders and/or nephrotic syndrome
|
|
ES2929025T3
(es)
|
2012-05-14 |
2022-11-24 |
Boehringer Ingelheim Int |
Linagliptina, un derivado de xantina como inhibidor de dpp-4, para su uso en el tratamiento del SRIS y/o de la septicemia
|
|
WO2013174767A1
(en)
|
2012-05-24 |
2013-11-28 |
Boehringer Ingelheim International Gmbh |
A xanthine derivative as dpp -4 inhibitor for use in modifying food intake and regulating food preference
|
|
JP6374862B2
(ja)
|
2012-05-24 |
2018-08-15 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
自己免疫性糖尿病、特に、ladaの治療に使用するためのdpp−4阻害剤としてのキサンチン誘導体
|
|
EP2854824A1
(en)
|
2012-05-25 |
2015-04-08 |
Boehringer Ingelheim International GmbH |
Use of keratinocytes as a biologically active substance in the treatment of wounds, such as diabetic wounds, optionally in combination with a dpp-4 inhibitor
|
|
CN103509023B
(zh)
*
|
2012-06-20 |
2014-08-27 |
成都苑东药业有限公司 |
黄嘌呤衍生物
|
|
CN103509022B
(zh)
*
|
2012-06-20 |
2015-04-01 |
成都苑东药业有限公司 |
黄嘌呤衍生物
|
|
IN2015DN00280A
(enExample)
|
2012-08-13 |
2015-06-12 |
Sandoz Ag |
|
|
WO2014045266A1
(en)
|
2012-09-24 |
2014-03-27 |
Ulf Eriksson |
Treatment of type 2 diabetes and related conditions
|
|
CN103709163B
(zh)
*
|
2012-09-29 |
2016-12-21 |
齐鲁制药有限公司 |
黄嘌呤衍生物、其制备方法及用途
|
|
UA116217C2
(uk)
|
2012-10-09 |
2018-02-26 |
Санофі |
Пептидна сполука як подвійний агоніст рецепторів glp1-1 та глюкагону
|
|
CN103319483B
(zh)
*
|
2012-10-19 |
2016-08-03 |
药源药物化学(上海)有限公司 |
一种利拉列汀重要中间体的制备方法
|
|
WO2014074668A1
(en)
|
2012-11-08 |
2014-05-15 |
Arena Pharmaceuticals, Inc. |
Modulators of gpr119 and the treatment of disorders related thereto
|
|
CN105073749A
(zh)
*
|
2012-12-17 |
2015-11-18 |
迈兰实验室有限公司 |
制备利拉利汀的改进方法
|
|
SG10201705097PA
(en)
|
2012-12-21 |
2017-07-28 |
Sanofi Sa |
Functionalized exendin-4 derivatives
|
|
CN103936737B
(zh)
*
|
2013-01-23 |
2016-09-14 |
成都苑东生物制药股份有限公司 |
黄嘌呤衍生物
|
|
CN103936740B
(zh)
*
|
2013-01-23 |
2016-06-29 |
成都苑东生物制药股份有限公司 |
黄嘌呤衍生物
|
|
CN103936738B
(zh)
*
|
2013-01-23 |
2016-11-23 |
成都苑东生物制药股份有限公司 |
黄嘌呤衍生物
|
|
CN103936739B
(zh)
*
|
2013-01-23 |
2016-08-31 |
成都苑东生物制药股份有限公司 |
黄嘌呤衍生物
|
|
WO2014140284A1
(en)
|
2013-03-15 |
2014-09-18 |
Boehringer Ingelheim International Gmbh |
Use of linagliptin in cardio- and renoprotective antidiabetic therapy
|
|
CA3208188A1
(en)
|
2013-03-15 |
2014-09-25 |
Takeda Pharmaceutical Company Limited |
Anti-plasma kallikrein antibodies
|
|
US20140303097A1
(en)
|
2013-04-05 |
2014-10-09 |
Boehringer Ingelheim International Gmbh |
Pharmaceutical composition, methods for treating and uses thereof
|
|
CA2812519A1
(en)
|
2013-04-05 |
2014-10-05 |
Boehringer Ingelheim International Gmbh |
Pharmaceutical composition, methods for treating and uses thereof
|
|
US11813275B2
(en)
|
2013-04-05 |
2023-11-14 |
Boehringer Ingelheim International Gmbh |
Pharmaceutical composition, methods for treating and uses thereof
|
|
TR201901110T4
(tr)
|
2013-04-05 |
2019-02-21 |
Boehringer Ingelheim Int |
Empagliflozinin terapötik kullanımları.
|
|
HK1215378A1
(zh)
|
2013-04-18 |
2016-08-26 |
勃林格殷格翰国际有限公司 |
药物组合物、治疗方法及其用途
|
|
US20140371243A1
(en)
*
|
2013-06-14 |
2014-12-18 |
Boehringer Ingelheim International Gmbh |
Medical use of a dpp-4 inhibitor
|
|
CN104292228B
(zh)
*
|
2013-07-16 |
2016-03-30 |
成都苑东生物制药股份有限公司 |
一种黄嘌呤化合物的多晶型及其制备方法、用途
|
|
WO2015011609A1
(en)
|
2013-07-23 |
2015-01-29 |
Ranbaxy Laboratories Limited |
Process for the preparation of linagliptin and an intermediate thereof
|
|
CN104418857A
(zh)
*
|
2013-08-22 |
2015-03-18 |
北京蓝丹医药科技有限公司 |
无定型利格列汀及其制备方法
|
|
EP3080149A1
(en)
|
2013-12-13 |
2016-10-19 |
Sanofi |
Dual glp-1/glucagon receptor agonists
|
|
TW201609795A
(zh)
|
2013-12-13 |
2016-03-16 |
賽諾菲公司 |
作為雙重glp-1/gip受體促效劑的艾塞那肽-4(exendin-4)胜肽類似物
|
|
WO2015086729A1
(en)
|
2013-12-13 |
2015-06-18 |
Sanofi |
Dual glp-1/gip receptor agonists
|
|
WO2015086730A1
(en)
|
2013-12-13 |
2015-06-18 |
Sanofi |
Non-acylated exendin-4 peptide analogues
|
|
CN104725379A
(zh)
*
|
2013-12-24 |
2015-06-24 |
杭州民生药物研究院有限公司 |
嘌呤酮衍生物及其组合物的制备方法与用途
|
|
EP3110449B1
(en)
*
|
2014-02-28 |
2023-06-28 |
Boehringer Ingelheim International GmbH |
Medical use of a dpp-4 inhibitor
|
|
TW201625669A
(zh)
|
2014-04-07 |
2016-07-16 |
賽諾菲公司 |
衍生自艾塞那肽-4(Exendin-4)之肽類雙重GLP-1/升糖素受體促效劑
|
|
TW201625670A
(zh)
|
2014-04-07 |
2016-07-16 |
賽諾菲公司 |
衍生自exendin-4之雙重glp-1/升糖素受體促效劑
|
|
TW201625668A
(zh)
|
2014-04-07 |
2016-07-16 |
賽諾菲公司 |
作為胜肽性雙重glp-1/昇糖素受體激動劑之艾塞那肽-4衍生物
|
|
US9932381B2
(en)
|
2014-06-18 |
2018-04-03 |
Sanofi |
Exendin-4 derivatives as selective glucagon receptor agonists
|
|
CN104557935B
(zh)
*
|
2015-01-27 |
2016-08-17 |
江苏嘉逸医药有限公司 |
制备(r)-8-(3-氨基哌啶-1-基)-黄嘌呤的提纯方法
|
|
MX386778B
(es)
|
2015-03-09 |
2025-03-19 |
Intekrin Therapeutics Inc |
Métodos para el tratamiento de enfermedad de hígado graso no alcohólico y/o lipodistrofia.
|
|
AR105319A1
(es)
|
2015-06-05 |
2017-09-27 |
Sanofi Sa |
Profármacos que comprenden un conjugado agonista dual de glp-1 / glucagón conector ácido hialurónico
|
|
EP3313841A1
(en)
|
2015-06-25 |
2018-05-02 |
Boehringer Ingelheim International GmbH |
Process for the preparation of a xanthine-based compound
|
|
AR105284A1
(es)
|
2015-07-10 |
2017-09-20 |
Sanofi Sa |
Derivados de exendina-4 como agonistas peptídicos duales específicos de los receptores de glp-1 / glucagón
|
|
CN108174596A
(zh)
|
2015-10-09 |
2018-06-15 |
赫克萨尔股份公司 |
包含8-[(3r)-3-氨基-1-哌啶基]-7-(2-丁炔-1-基)-3,7-二氢-3-甲基-1-[4-甲基-2-喹唑啉基)甲基]-1h-嘌呤-2,6-二酮或其药学上可接受的盐的药物组合物
|
|
EP3156048A1
(en)
|
2015-10-13 |
2017-04-19 |
Galenicum Health S.L. |
Stable pharmaceutical composition of linagliptin in the form of immediate release tablets
|
|
CN105566271B
(zh)
*
|
2015-12-03 |
2019-09-13 |
福建医科大学 |
双黄酮化合物及其制备治疗癌症的药物的用途
|
|
BR112018072401A2
(pt)
|
2016-06-10 |
2019-02-19 |
Boehringer Ingelheim International Gmbh |
combinações de linagliptina e metformina
|
|
AU2017357589B2
(en)
|
2016-11-10 |
2023-05-11 |
Boehringer Ingelheim International Gmbh |
Pharmaceutical composition, methods for treating and uses thereof
|
|
US11285180B2
(en)
|
2016-12-06 |
2022-03-29 |
Inserm (Institut National De La Sante Et De La Recherche Medicale) |
Methods of enhancing the potency of incretin-based drugs in subjects in need thereof
|
|
WO2018187350A1
(en)
|
2017-04-03 |
2018-10-11 |
Coherus Biosciences Inc. |
PPARγ AGONIST FOR TREATMENT OF PROGRESSIVE SUPRANUCLEAR PALSY
|
|
KR102469957B1
(ko)
|
2017-06-30 |
2022-11-24 |
한미약품 주식회사 |
리나글립틴, 메트포르민 및 항산화제를 포함하는, 안정성이 개선된 약제학적 조성물
|
|
CN107325114B
(zh)
*
|
2017-07-04 |
2019-06-11 |
吉林省爱诺德生物工程有限公司 |
一种头孢洛林酯中间体的制备方法
|
|
PL3461819T3
(pl)
|
2017-09-29 |
2020-11-30 |
Probiodrug Ag |
Inhibitory cyklazy glutaminylowej
|
|
KR102500835B1
(ko)
|
2017-10-24 |
2023-02-17 |
한미약품 주식회사 |
리나글립틴 및 메트포르민을 포함하는 복합제제 및 그의 제조방법
|
|
CN108299436B
(zh)
*
|
2018-02-09 |
2020-01-17 |
上海慈瑞医药科技股份有限公司 |
黄嘌呤类化合物及其药物组合物和应用
|
|
KR102208009B1
(ko)
*
|
2018-04-26 |
2021-01-28 |
주식회사 경보제약 |
신규한 리나글립틴 염 화합물, 이의 제조 방법 및 신규한 리나글립틴 염 화합물로부터 제조된 리나글립틴
|
|
KR102647472B1
(ko)
|
2018-07-31 |
2024-03-14 |
한미약품 주식회사 |
디펩티딜 펩티다아제-4 억제제 및 메트포르민을 포함하는 경구용 고형 복합제제 및 이의 제조방법
|
|
HU231374B1
(hu)
|
2018-08-06 |
2023-04-28 |
Richter Gedeon Nyrt. |
Eljárás BOC-Linagliptin előállítására
|
|
CN113543852A
(zh)
|
2019-03-06 |
2021-10-22 |
第一三共株式会社 |
吡咯并吡唑衍生物
|
|
CN110305131B
(zh)
*
|
2019-07-03 |
2021-12-31 |
山东百诺医药股份有限公司 |
利格列汀新晶型及其制备方法
|
|
EP3811930A1
(en)
|
2019-10-24 |
2021-04-28 |
Authenda Pharmaceuticals AG |
Oral gliptin compositions and method for preparation thereof
|
|
CN113423404B
(zh)
*
|
2019-12-02 |
2023-09-29 |
成都苑东生物制药股份有限公司 |
一种黄嘌呤衍生物药物组合物及其制备方法
|
|
WO2021160608A1
(en)
|
2020-02-13 |
2021-08-19 |
Zakłady Farmaceutyczne POLPHARMA S.A. |
Pharmaceutical composition comprising linagliptin and metformin
|
|
CN112876409A
(zh)
*
|
2021-01-20 |
2021-06-01 |
都创(上海)医药科技股份有限公司 |
一种2-(5-溴-6-甲氧基吡啶-2-基)乙腈及其衍生物的合成方法
|
|
WO2023002036A1
(en)
|
2021-07-22 |
2023-01-26 |
Krka, D.D., Novo Mesto |
Process for preparing a pharmaceutical composition comprising linagliptin and metformin hydrochloride
|
|
KR20230055762A
(ko)
|
2021-10-19 |
2023-04-26 |
한미약품 주식회사 |
메트포르민, 리나글립틴 및 메글루민을 포함하는 약제학적 복합제제
|
|
WO2023156675A1
(en)
|
2022-02-21 |
2023-08-24 |
Krka, D.D., Novo Mesto |
Process for purification of linagliptin
|
|
KR20230126664A
(ko)
|
2022-02-23 |
2023-08-30 |
주식회사 제뉴원사이언스 |
리나글립틴 또는 이의 약학적으로 허용가능한 염과 메트포르민 또는 이의 약학적으로 허용가능한 염을 포함하는 약물방출이 조절된 약제학적 복합제제
|
|
CN114989147B
(zh)
*
|
2022-06-20 |
2024-05-17 |
广东晨康生物科技有限公司 |
一种苯并嘧啶类化合物或其药学上可接受的盐及其制备方法和应用
|
|
EP4349837A1
(en)
|
2022-10-05 |
2024-04-10 |
Zaklady Farmaceutyczne "Polpharma" S.A. |
A pharmaceutical intermediate
|
|
WO2024091863A1
(en)
|
2022-10-25 |
2024-05-02 |
Starrock Pharma Llc |
Combinatorial, and rotational combinatorial therapies for obesity and other diseases
|
|
WO2025227129A2
(en)
|
2024-04-25 |
2025-10-30 |
Starrock Pharma Llc |
Delivery vehicles comprising proglucagon derived polypeptides and anabolic polypeptides and uses thereof
|
|
CN118496229A
(zh)
*
|
2024-05-13 |
2024-08-16 |
迪嘉药业集团股份有限公司 |
一种利格列汀新晶型及其制备方法
|