JP2005536559A5 - - Google Patents
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- Publication number
- JP2005536559A5 JP2005536559A5 JP2004532055A JP2004532055A JP2005536559A5 JP 2005536559 A5 JP2005536559 A5 JP 2005536559A5 JP 2004532055 A JP2004532055 A JP 2004532055A JP 2004532055 A JP2004532055 A JP 2004532055A JP 2005536559 A5 JP2005536559 A5 JP 2005536559A5
- Authority
- JP
- Japan
- Prior art keywords
- compound
- formula
- producing
- nitrating agent
- reaction
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- 0 C*(C)*(*(C)*)*(C)N Chemical compound C*(C)*(*(C)*)*(C)N 0.000 description 1
- FVVGXRJNWIYMNJ-UHFFFAOYSA-N CC(C1)C1(C)N Chemical compound CC(C1)C1(C)N FVVGXRJNWIYMNJ-UHFFFAOYSA-N 0.000 description 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT001861A ITMI20021861A1 (it) | 2002-08-29 | 2002-08-29 | Procedimento di sintesi di nitrossialchilesteri di acidi carbossilici, intermedi impiegabili in detto procedimento e loro preparazione. |
| PCT/EP2003/008700 WO2004020385A1 (en) | 2002-08-29 | 2003-08-06 | Process for preparing nitrooxyalkyl substituted esters of carboxylic acids, intermediates useful in said process and preparation thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2005536559A JP2005536559A (ja) | 2005-12-02 |
| JP2005536559A5 true JP2005536559A5 (https=) | 2006-09-21 |
Family
ID=31972201
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004532054A Expired - Fee Related JP4528123B2 (ja) | 2002-08-29 | 2003-08-06 | ナプロキセンのニトロオキシ誘導体の製造法 |
| JP2004532055A Ceased JP2005536559A (ja) | 2002-08-29 | 2003-08-06 | カルボン酸のニトロオキシアルキル置換エステルの製造法、その方法において有用な中間体およびその製造法 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004532054A Expired - Fee Related JP4528123B2 (ja) | 2002-08-29 | 2003-08-06 | ナプロキセンのニトロオキシ誘導体の製造法 |
Country Status (20)
| Country | Link |
|---|---|
| US (3) | US7723382B2 (https=) |
| EP (2) | EP1532098B1 (https=) |
| JP (2) | JP4528123B2 (https=) |
| KR (1) | KR101100064B1 (https=) |
| CN (1) | CN1326830C (https=) |
| AT (1) | ATE449060T1 (https=) |
| AU (2) | AU2003266966B2 (https=) |
| CA (1) | CA2497187C (https=) |
| CY (1) | CY1109769T1 (https=) |
| DE (1) | DE60330152D1 (https=) |
| DK (1) | DK1532098T3 (https=) |
| ES (1) | ES2335656T3 (https=) |
| IL (1) | IL166587A0 (https=) |
| IT (1) | ITMI20021861A1 (https=) |
| NZ (1) | NZ537993A (https=) |
| PT (1) | PT1532098E (https=) |
| RU (1) | RU2315035C2 (https=) |
| SI (1) | SI1532098T1 (https=) |
| WO (2) | WO2004020385A1 (https=) |
| ZA (1) | ZA200500890B (https=) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2491127A1 (en) | 2002-07-03 | 2004-01-15 | Nitromed, Inc. | Nitrosated nonsteroidal antiinflammatory compounds, compositions and methods of use |
| ITMI20021861A1 (it) * | 2002-08-29 | 2004-02-29 | Nicox Sa | Procedimento di sintesi di nitrossialchilesteri di acidi carbossilici, intermedi impiegabili in detto procedimento e loro preparazione. |
| JP2008521770A (ja) * | 2004-11-25 | 2008-06-26 | ニコックス エス エイ | ハロゲノアルキルナイトレートの製造方法 |
| WO2009149053A2 (en) * | 2008-06-02 | 2009-12-10 | Dr. Reddy's Laboratories Ltd. | Naproxcinod process and solid dispersion |
| ITRM20080325A1 (it) * | 2008-06-20 | 2009-12-21 | Nicox Sa | Metodo per purificare 4-(nitroosi)butil(2s)-2-(6-metossi-2-naftil) propanoato |
| US8062653B2 (en) | 2009-02-18 | 2011-11-22 | Bezwada Biomedical, Llc | Controlled release of nitric oxide and drugs from functionalized macromers and oligomers |
| CN101885684B (zh) * | 2010-07-01 | 2013-10-30 | 南京中医药大学 | 带有一氧化氮供体的芳香酸前体药物及其制备方法和其应用 |
| TWI417276B (zh) * | 2011-03-01 | 2013-12-01 | Everlight Chem Ind Corp | ２-（ｓ）-（６-甲氧基-２-萘基）-丙酸之酸酐衍生物、其製法暨及其用途 |
| CA2897571C (en) | 2013-01-21 | 2018-12-18 | Apparao Satyam | Nitric oxide releasing prodrugs of therapeutic agents containing at least one carboxylic acid group |
| MX2021004581A (es) * | 2018-10-25 | 2021-06-15 | Dsm Ip Assets Bv | Composiciones acuosas que comprenden omega nitrooxi-1-alcanoles. |
| CN111333560B (zh) * | 2020-04-13 | 2024-01-23 | 合肥工业大学 | 一种制备螺环β-内酰胺的方法 |
| CN112321420A (zh) * | 2020-11-03 | 2021-02-05 | 浙江海翔川南药业有限公司 | 一种萘普生杂质及其制备方法 |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5279359A (en) * | 1975-12-26 | 1977-07-04 | Hitachi Ltd | Cleaning material arrestor |
| US5057427A (en) * | 1988-04-07 | 1991-10-15 | Sepracor, Inc. | Method for resolution of stereoisomers |
| JPH05279359A (ja) | 1992-02-06 | 1993-10-26 | Kawaken Fine Chem Co Ltd | アポビンカミン酸エステルの製造方法 |
| JPH05247015A (ja) * | 1992-03-05 | 1993-09-24 | Nippon Iyakuhin Kogyo Kk | 新規ピペラジン誘導体 |
| DE69412109T2 (de) | 1993-10-06 | 1999-01-21 | Nicox S.A., Paris | Salzetersaüreester mit entzündungshemmender und/oder schmerzlindernder wirkung und verfahren zu deren herstellung |
| SI0759899T1 (en) | 1994-05-10 | 1999-12-31 | Nicox S.A. | Nitro compounds and their compositions having anti-inflammatory, analgesic and anti-thrombotic acitivities |
| IT1276071B1 (it) * | 1995-10-31 | 1997-10-24 | Nicox Ltd | Compositi ad attivita' anti-infiammatoria |
| CA2262788A1 (en) * | 1996-08-16 | 1998-02-26 | Gustavo Enrique Aldoma | Non-ulcerogenic analgesic/anti-inflammatory clonixin derivative |
| IT1288123B1 (it) * | 1996-09-04 | 1998-09-10 | Nicox Sa | Uso di nitroderivati per l'incontinenza urinaria |
| FR2757159B1 (fr) | 1996-12-12 | 1999-12-17 | Hoechst Marion Roussel Inc | Nouveaux derives nitres analgesiques, anti-inflammatoires et anti-thrombotiques, leur procede de preparation, leur application comme medicaments |
| IT1311924B1 (it) * | 1999-04-13 | 2002-03-20 | Nicox Sa | Composti farmaceutici. |
| IT1313596B1 (it) | 1999-08-04 | 2002-09-09 | Nicox Sa | Processo per la preparazione di nitrossialchil esteri del naproxene |
| IT1314184B1 (it) * | 1999-08-12 | 2002-12-06 | Nicox Sa | Composizioni farmaceutiche per la terapia di condizioni di stressossidativo |
| US6429223B1 (en) * | 2000-06-23 | 2002-08-06 | Medinox, Inc. | Modified forms of pharmacologically active agents and uses therefor |
| ITMI20010985A1 (it) * | 2001-05-15 | 2002-11-15 | Nicox Sa | Farmaci per il morbo di alzheimer |
| ITMI20011307A1 (it) * | 2001-06-21 | 2002-12-21 | Nicox Sa | Farmaci per l'epilessia |
| ITMI20011308A1 (it) * | 2001-06-21 | 2002-12-21 | Nicox Sa | Farmaci per il dolore cronico |
| WO2003045896A1 (en) * | 2001-11-27 | 2003-06-05 | Astrazeneca Ab | New process |
| WO2003103602A2 (en) * | 2002-06-11 | 2003-12-18 | Nitromed, Inc. | Nitrosated and/or nitrosylated cyclooxygenase-2 selective inhibitors, compositions and methods of use |
| CA2491127A1 (en) * | 2002-07-03 | 2004-01-15 | Nitromed, Inc. | Nitrosated nonsteroidal antiinflammatory compounds, compositions and methods of use |
| ITMI20021861A1 (it) * | 2002-08-29 | 2004-02-29 | Nicox Sa | Procedimento di sintesi di nitrossialchilesteri di acidi carbossilici, intermedi impiegabili in detto procedimento e loro preparazione. |
| US7199947B2 (en) * | 2004-12-28 | 2007-04-03 | Motorola Inc. | Miniature digital camera lens |
-
2002
- 2002-08-29 IT IT001861A patent/ITMI20021861A1/it unknown
-
2003
- 2003-08-06 AU AU2003266966A patent/AU2003266966B2/en not_active Ceased
- 2003-08-06 DE DE60330152T patent/DE60330152D1/de not_active Expired - Lifetime
- 2003-08-06 AU AU2003266261A patent/AU2003266261A1/en not_active Abandoned
- 2003-08-06 WO PCT/EP2003/008700 patent/WO2004020385A1/en not_active Ceased
- 2003-08-06 WO PCT/EP2003/008698 patent/WO2004020384A1/en not_active Ceased
- 2003-08-06 NZ NZ537993A patent/NZ537993A/en not_active IP Right Cessation
- 2003-08-06 CN CNB038206056A patent/CN1326830C/zh not_active Expired - Fee Related
- 2003-08-06 ES ES03747879T patent/ES2335656T3/es not_active Expired - Lifetime
- 2003-08-06 PT PT03747879T patent/PT1532098E/pt unknown
- 2003-08-06 EP EP03747879A patent/EP1532098B1/en not_active Expired - Lifetime
- 2003-08-06 US US10/522,986 patent/US7723382B2/en not_active Expired - Fee Related
- 2003-08-06 US US10/523,722 patent/US7199258B2/en not_active Expired - Fee Related
- 2003-08-06 RU RU2005104419/04A patent/RU2315035C2/ru not_active IP Right Cessation
- 2003-08-06 SI SI200331743T patent/SI1532098T1/sl unknown
- 2003-08-06 EP EP03790866A patent/EP1537070A1/en not_active Withdrawn
- 2003-08-06 CA CA2497187A patent/CA2497187C/en not_active Expired - Fee Related
- 2003-08-06 KR KR1020057003509A patent/KR101100064B1/ko not_active Expired - Fee Related
- 2003-08-06 JP JP2004532054A patent/JP4528123B2/ja not_active Expired - Fee Related
- 2003-08-06 DK DK03747879.9T patent/DK1532098T3/da active
- 2003-08-06 JP JP2004532055A patent/JP2005536559A/ja not_active Ceased
- 2003-08-06 AT AT03747879T patent/ATE449060T1/de active
-
2005
- 2005-01-31 ZA ZA200500890A patent/ZA200500890B/xx unknown
- 2005-01-31 IL IL16658705A patent/IL166587A0/xx not_active IP Right Cessation
-
2010
- 2010-02-10 CY CY20101100132T patent/CY1109769T1/el unknown
- 2010-03-30 US US12/750,381 patent/US20100217028A1/en not_active Abandoned
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