IT1314184B1 - Composizioni farmaceutiche per la terapia di condizioni di stressossidativo - Google Patents
Composizioni farmaceutiche per la terapia di condizioni di stressossidativoInfo
- Publication number
- IT1314184B1 IT1314184B1 IT1999MI001817A ITMI991817A IT1314184B1 IT 1314184 B1 IT1314184 B1 IT 1314184B1 IT 1999MI001817 A IT1999MI001817 A IT 1999MI001817A IT MI991817 A ITMI991817 A IT MI991817A IT 1314184 B1 IT1314184 B1 IT 1314184B1
- Authority
- IT
- Italy
- Prior art keywords
- therapy
- stress
- pharmaceutical compositions
- oxidative conditions
- linear
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/10—Expectorants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/12—Mucolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C203/00—Esters of nitric or nitrous acid
- C07C203/02—Esters of nitric acid
- C07C203/04—Esters of nitric acid having nitrate groups bound to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C219/00—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C219/02—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C219/20—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated
- C07C219/22—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C219/00—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C219/24—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups or amino groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/40—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino groups bound to carbon atoms of at least one six-membered aromatic ring and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/42—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino groups bound to carbon atoms of at least one six-membered aromatic ring and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton with carboxyl groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by saturated carbon chains
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
- C07C233/24—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
- C07C233/25—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C07C317/44—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
- C07D219/04—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
- C07D219/08—Nitrogen atoms
- C07D219/10—Nitrogen atoms attached in position 9
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D235/28—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D307/84—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D309/28—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/30—Oxygen atoms, e.g. delta-lactones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/18—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 one oxygen and one nitrogen atom, e.g. guanine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se)
- C07F9/3804—Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se) not used, see subgroups
- C07F9/3839—Polyphosphonic acids
- C07F9/3873—Polyphosphonic acids containing nitrogen substituent, e.g. N.....H or N-hydrocarbon group which can be substituted by halogen or nitro(so), N.....O, N.....S, N.....C(=X)- (X =O, S), N.....N, N...C(=X)...N (X =O, S)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/24—Condensed ring systems having three or more rings
- C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/08—One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane
Priority Applications (33)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT1999MI001817A IT1314184B1 (it) | 1999-08-12 | 1999-08-12 | Composizioni farmaceutiche per la terapia di condizioni di stressossidativo |
JP2001516885A JP2003515526A (ja) | 1999-08-12 | 2000-07-27 | 医薬化合物 |
EP00953102A EP1252133B1 (en) | 1999-08-12 | 2000-07-27 | Pharmaceutical compounds |
SI200030734T SI1252133T1 (en) | 1999-08-12 | 2000-07-27 | Pharmaceutical compounds |
CA002381409A CA2381409A1 (en) | 1999-08-12 | 2000-07-27 | Nitric ester derivatives |
PT00953102T PT1252133E (pt) | 1999-08-12 | 2000-07-27 | Compostos farmaceuticos |
AU65670/00A AU781643B2 (en) | 1999-08-12 | 2000-07-27 | Pharmaceutical compounds |
US10/048,469 US7186753B1 (en) | 1999-08-12 | 2000-07-27 | Pharmaceutical compounds |
MXPA02001519A MXPA02001519A (es) | 1999-08-12 | 2000-07-27 | Compuestos farmaceuticos. |
CNB008140499A CN1289466C (zh) | 1999-08-12 | 2000-07-27 | 药用化合物 |
DK00953102T DK1252133T3 (da) | 1999-08-12 | 2000-07-27 | Farmaceutiske forbindelser |
BR0013264-0A BR0013264A (pt) | 1999-08-12 | 2000-07-27 | Compostos ou seus sais, uso dos mesmos, e, formulações farmacêuticas |
CNB2006101362310A CN100528834C (zh) | 1999-08-12 | 2000-07-27 | 药用化合物 |
KR1020067024051A KR100760394B1 (ko) | 1999-08-12 | 2000-07-27 | 약제화합물들 |
PCT/EP2000/007225 WO2001012584A2 (en) | 1999-08-12 | 2000-07-27 | Pharmaceutical compounds |
PL353451A PL203200B1 (pl) | 1999-08-12 | 2000-07-27 | Związki farmaceutyczne, ich zastosowanie, formulacje farmaceutyczne, ester 4'-acetyloaminofenylowy kwasu 4-nitroksymasłowego oraz zastosowanie tego estru |
ES00953102T ES2243292T3 (es) | 1999-08-12 | 2000-07-27 | Compuestos farmaceuticos. |
DE60020741T DE60020741T2 (de) | 1999-08-12 | 2000-07-27 | Pharmazeutische verbindungen |
NZ516889A NZ516889A (en) | 1999-08-12 | 2000-07-27 | Pharmaceutical compounds useful in oxidative stress and/or endothelial dysfunction of moderate intensity |
AT00953102T ATE297375T1 (de) | 1999-08-12 | 2000-07-27 | Pharmazeutische verbindungen |
RU2002103509/04A RU2264383C2 (ru) | 1999-08-12 | 2000-07-27 | Лекарственные вещества и фармацевтические композиции на их основе для использования в случаях окислительного стресса |
NZ535559A NZ535559A (en) | 1999-08-12 | 2000-07-27 | Pharmaceutical compounds useful in oxidative stress and/or endothelial dysfunction of moderate intensity |
EP05104064A EP1593664A1 (en) | 1999-08-12 | 2000-07-27 | Nitric esters derivatives of ferulic acid and sulindac with pharmaceutical activity |
HU0203939A HUP0203939A3 (en) | 1999-08-12 | 2000-07-27 | Pharmaceutical compounds and compositions containing them and their use |
CA2698353A CA2698353A1 (en) | 1999-08-12 | 2000-07-27 | Pharmaceutical compounds |
KR1020027001883A KR100687809B1 (ko) | 1999-08-12 | 2000-07-27 | 약제화합물들 |
IL14780100A IL147801A0 (en) | 1999-08-12 | 2000-07-27 | Pharmaceutical compounds |
ZA200200628A ZA200200628B (en) | 1999-08-12 | 2002-01-23 | Pharmaceutical compounds. |
NO20020623A NO328498B1 (no) | 1999-08-12 | 2002-02-08 | Forbindelser, farmasoytiske formuleringer inneholdende slike, og anvendelse av forbindelsene til fremstilling av legemidler |
AU2005202824A AU2005202824B2 (en) | 1999-08-12 | 2005-06-28 | Pharmaceutical compounds |
US11/642,783 US7399878B2 (en) | 1999-08-12 | 2006-12-21 | Pharmaceutical compounds |
US12/132,245 US7759392B2 (en) | 1999-08-12 | 2008-06-03 | Pharmaceutical compounds |
NO20093253A NO20093253L (no) | 1999-08-12 | 2009-10-29 | Forbindelser, farmasoytiske formuleringer og anvendelse av forbindelsene til fremstilling av legemiddel |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT1999MI001817A IT1314184B1 (it) | 1999-08-12 | 1999-08-12 | Composizioni farmaceutiche per la terapia di condizioni di stressossidativo |
Publications (3)
Publication Number | Publication Date |
---|---|
ITMI991817A0 ITMI991817A0 (it) | 1999-08-12 |
ITMI991817A1 ITMI991817A1 (it) | 2001-02-12 |
IT1314184B1 true IT1314184B1 (it) | 2002-12-06 |
Family
ID=11383554
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT1999MI001817A IT1314184B1 (it) | 1999-08-12 | 1999-08-12 | Composizioni farmaceutiche per la terapia di condizioni di stressossidativo |
Country Status (23)
Country | Link |
---|---|
US (3) | US7186753B1 (it) |
EP (2) | EP1593664A1 (it) |
JP (1) | JP2003515526A (it) |
KR (2) | KR100760394B1 (it) |
CN (2) | CN100528834C (it) |
AT (1) | ATE297375T1 (it) |
AU (1) | AU781643B2 (it) |
BR (1) | BR0013264A (it) |
CA (2) | CA2381409A1 (it) |
DE (1) | DE60020741T2 (it) |
DK (1) | DK1252133T3 (it) |
ES (1) | ES2243292T3 (it) |
HU (1) | HUP0203939A3 (it) |
IL (1) | IL147801A0 (it) |
IT (1) | IT1314184B1 (it) |
MX (1) | MXPA02001519A (it) |
NO (2) | NO328498B1 (it) |
NZ (2) | NZ535559A (it) |
PL (1) | PL203200B1 (it) |
PT (1) | PT1252133E (it) |
RU (1) | RU2264383C2 (it) |
WO (1) | WO2001012584A2 (it) |
ZA (1) | ZA200200628B (it) |
Families Citing this family (73)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5824669A (en) | 1996-03-22 | 1998-10-20 | Nitromed, Inc. | Nitrosated and nitrosylated compounds and compositions and their use for treating respiratory disorders |
US20050137191A1 (en) * | 1996-06-04 | 2005-06-23 | Thatcher Gregory R. | Nitrate esters and their use for mitigating cellular damage |
IT1288123B1 (it) | 1996-09-04 | 1998-09-10 | Nicox Sa | Uso di nitroderivati per l'incontinenza urinaria |
US6852739B1 (en) | 1999-02-26 | 2005-02-08 | Nitromed Inc. | Methods using proton pump inhibitors and nitric oxide donors |
IT1314184B1 (it) * | 1999-08-12 | 2002-12-06 | Nicox Sa | Composizioni farmaceutiche per la terapia di condizioni di stressossidativo |
IT1317735B1 (it) * | 2000-01-26 | 2003-07-15 | Nicox Sa | Sali di agenti antimicrobici. |
AU7007001A (en) | 2000-06-22 | 2002-01-02 | Nitromed Inc | Nitrosated and nitrosylated taxanes, compositions and methods of use |
IT1319202B1 (it) * | 2000-10-12 | 2003-09-26 | Nicox Sa | Farmaci per le malattie a base infiammatoria. |
US6706724B2 (en) | 2000-12-21 | 2004-03-16 | Nitromed, Inc. | Substituted aryl compounds as novel cyclooxygenase-2 selective inhibitors, compositions and methods of use |
EP1406608B1 (en) * | 2001-05-02 | 2009-07-29 | Nitromed, Inc. | Nitrosated and nitrosylated nebivolol and its metabolites, compositions and methods of use |
AU2008201838B2 (en) * | 2001-05-02 | 2010-07-29 | Nicox S.A. | Nitrosated and nitrosylated nebivolol and its metabolites, compositions and methods of use |
SE0101702D0 (sv) | 2001-05-15 | 2001-05-15 | Ardenia Investments Ltd | Novel potentiating compounds |
GB0111872D0 (en) | 2001-05-15 | 2001-07-04 | Northwick Park Inst For Medica | Therapeutic agents and methods |
ITMI20011307A1 (it) * | 2001-06-21 | 2002-12-21 | Nicox Sa | Farmaci per l'epilessia |
ITMI20011308A1 (it) | 2001-06-21 | 2002-12-21 | Nicox Sa | Farmaci per il dolore cronico |
ITMI20011744A1 (it) * | 2001-08-09 | 2003-02-09 | Nicox Sa | Farmaci per le vasculopatie |
EP2319518A1 (en) | 2002-02-04 | 2011-05-11 | ALFAMA-Investigacao e Desenvolvimento de Produtos Farmaceuticos Lda. | Use of CO-releasing compounds for the manufacture of a medicament for the treatment of inflammatory diseases |
WO2003086282A2 (en) * | 2002-04-05 | 2003-10-23 | Nitromed, Inc. | Nitric oxide donors, compositions and methods of use |
EP1539185A4 (en) * | 2002-05-02 | 2006-04-05 | Osteoscreen Inc | METHODS AND COMPOSITIONS FOR STIMULATING BONE GROWTH USING NITRIC OXIDE FREEZING BISPHOSPHONATE CONJUGATES |
JP2006501161A (ja) | 2002-06-11 | 2006-01-12 | ニトロメッド インク. | ニトロソ化および/またはニトロシル化シクロオキシゲナーゼ−2選択的阻害剤、組成物ならびに使用方法 |
AU2003247792B2 (en) | 2002-07-03 | 2009-09-24 | Nicox S.A. | Nitrosated nonsteroidal antiinflammatory compounds, compositions and methods of use |
EP1542972A4 (en) | 2002-07-29 | 2008-01-23 | Nitromed Inc | CYCLOOXYGENASE-2 SELECTIVE INHIBITORS, COMPOSITION AND METHOD OF USE |
US7211590B2 (en) | 2002-08-01 | 2007-05-01 | Nitromed, Inc. | Nitrosated proton pump inhibitors, compositions and methods of use |
ITMI20021861A1 (it) * | 2002-08-29 | 2004-02-29 | Nicox Sa | Procedimento di sintesi di nitrossialchilesteri di acidi carbossilici, intermedi impiegabili in detto procedimento e loro preparazione. |
ITMI20022658A1 (it) | 2002-12-17 | 2004-06-18 | Nicox Sa | Farmaci per il dolore cronico. |
US7166638B2 (en) | 2003-05-27 | 2007-01-23 | Nicox S.A. | Statin derivatives |
US7169805B2 (en) | 2003-05-28 | 2007-01-30 | Nicox S.A. | Captopril derivatives |
MXPA05013771A (es) | 2003-06-19 | 2006-03-08 | Nicox Sa | Derivados de enalapril-nitroxiderivados y compuestos relacionados como inhibidores de la enzima que convierte la angiotensina para el tratamiento de enfermedades cardiovasculares. |
WO2005018561A2 (en) * | 2003-08-20 | 2005-03-03 | Nitromed, Inc. | Nitrosated and nitrosylated cardiovascular compounds, compositions and methods of use |
DE602004014822D1 (de) | 2003-11-20 | 2008-08-14 | Nicox Sa | Neues verfahren zur herstellung von nitrooxyderivaten von paracetamol |
DE602004019579D1 (de) * | 2003-12-02 | 2009-04-02 | Nicox Sa | Nitrooxyderivate von blutdrucksenkenden arzneimitteln |
AU2004294297A1 (en) * | 2003-12-02 | 2005-06-16 | Nicox S.A. | Nitrooxyderivatives of carvedilol and other beta blockers as antihypertensive drugs |
WO2005070006A2 (en) * | 2004-01-22 | 2005-08-04 | Nitromed, Inc. | Nitrosated and/or nitrosylated compounds, compositions and methods of use |
KR100503443B1 (ko) * | 2004-02-02 | 2005-07-22 | 한림제약(주) | 광학적으로 활성인 세티리진 또는 그의 염의 제조방법 |
CN1984871A (zh) | 2004-07-20 | 2007-06-20 | 尼科克斯公司 | 制备硝基氧基酯、硝基氧基硫酯、硝基氧基碳酸酯和硝基氧基硫代碳酸酯的方法、用于所述方法的中间体及其制备 |
TW200616604A (en) | 2004-08-26 | 2006-06-01 | Nicholas Piramal India Ltd | Nitric oxide releasing prodrugs containing bio-cleavable linker |
EP1789091B1 (en) | 2004-08-26 | 2010-08-25 | Piramal Life Sciences Limited | Prodrugs containing novel bio-cleavable linkers |
EP2057139B1 (en) * | 2006-07-18 | 2013-09-04 | Antibe Therapeutics Inc. | Hydrogen sulfide derivatives of non-steroidal anti-inflammatory drugs |
TW200831079A (en) | 2006-12-13 | 2008-08-01 | Merck & Co Inc | Angiotensin II receptor antagonists |
US20080317673A1 (en) * | 2007-06-20 | 2008-12-25 | Fatema Salem Al-Thallab | Method for diagnosing and treating bronchial asthma |
US20080319221A1 (en) * | 2007-06-22 | 2008-12-25 | Bernd Junker | Esters of Pentahydroxyhexylcarbamoyl Alkanoic Acids |
WO2009007230A1 (en) | 2007-07-09 | 2009-01-15 | Nicox S.A. | Use of nitric oxide releasing compounds in the treatment of chronic pain |
ES2441263T3 (es) | 2007-08-17 | 2014-02-03 | Council Of Scientific & Industrial Research | Derivados de paracetamol que liberan óxido nítrico |
US7709634B2 (en) * | 2007-09-20 | 2010-05-04 | Apotex Pharmachem Inc. | Amorphous form of rifaximin and processes for its preparation |
CA2930063C (en) | 2008-01-04 | 2017-01-31 | Schabar Research Associates Llc | Unit oral solid dose compositions composed of naproxen sodium and nizatidine |
CA2723725A1 (en) * | 2008-05-15 | 2009-11-19 | Merck Sharp & Dohme Corp. | Angiotensin ii receptor antagonists |
CA2728301A1 (en) * | 2008-07-03 | 2010-01-07 | Osteogenex Inc. | Vinpocetine and eburnamonine derivatives for promoting bone growth |
MD4009C2 (ro) * | 2008-07-15 | 2010-08-31 | Институт Химии Академии Наук Молдовы | Utilizarea 1-metil-4-(N-metilaminobutil-4)-β-carbolinei în calitate de remediu antituberculos |
EP2306995B1 (en) | 2008-08-01 | 2014-07-30 | OncoNOx ApS | Antitumor properties of no modified protease inhibitors |
WO2010108843A1 (en) | 2009-03-27 | 2010-09-30 | Nicox S.A. | Use of nitrooxyderivative of paracetamol for the treatment of muscular dystrophies |
FR2953145B1 (fr) * | 2009-11-30 | 2013-07-19 | Inst Francais Du Petrole | Solution absorbante contenant un inhibiteur de degradation derive de la pyrimidine ou de la triazine et procede d'absorption de composes acides contenus dans un effluent gazeux |
CN101863900B (zh) * | 2010-06-29 | 2012-07-25 | 天津药物研究院 | 一氧化氮供体型噻吩并吡啶衍生物、其制备方法和用途 |
CN102442908A (zh) * | 2010-10-14 | 2012-05-09 | 天津药物研究院 | 制备萘普西诺的中间体及方法 |
RU2584163C2 (ru) * | 2010-11-02 | 2016-05-20 | Нагоя Индастриал Сайенс Рисерч Инститьют | Производное транс-2-деценовой кислоты и содержащее его фармацевтическое средство |
JO3350B1 (ar) | 2011-03-07 | 2019-03-13 | Merck Sharp & Dohme | مشتقات حلقية غير متجانسة محتوية على مجموعات أمينو أولية ومركبات داي أزينيومديولات |
JP5978291B2 (ja) | 2011-04-19 | 2016-08-24 | アルファーマ インコーポレイテッドAlfama,Inc. | 一酸化炭素放出分子およびその使用 |
WO2013013179A1 (en) | 2011-07-21 | 2013-01-24 | Alfama, Inc. | Ruthenium carbon monoxide releasing molecules and uses thereof |
CN102557967A (zh) * | 2011-12-28 | 2012-07-11 | 合肥科尚医药科技有限公司 | 一种盐酸氨溴索的制备方法 |
WO2015023675A2 (en) | 2013-08-12 | 2015-02-19 | Pharmaceutical Manufacturing Research Services, Inc. | Extruded immediate release abuse deterrent pill |
US9492444B2 (en) | 2013-12-17 | 2016-11-15 | Pharmaceutical Manufacturing Research Services, Inc. | Extruded extended release abuse deterrent pill |
WO2015095391A1 (en) | 2013-12-17 | 2015-06-25 | Pharmaceutical Manufacturing Research Services, Inc. | Extruded extended release abuse deterrent pill |
DK3169315T3 (da) | 2014-07-17 | 2020-08-10 | Pharmaceutical Manufacturing Res Services In | Væskefyldt doseringsform til forhindring af misbrug med øjeblikkelig frigivelse |
EP3006453A1 (en) | 2014-10-08 | 2016-04-13 | Cosmo Technologies Ltd. | 17alpha-monoesters and 17alpha,21-diesters of cortexolone for use in the treatment of tumors |
US20160106737A1 (en) | 2014-10-20 | 2016-04-21 | Pharmaceutical Manufacturing Research Services, Inc. | Extended Release Abuse Deterrent Liquid Fill Dosage Form |
CA3020090A1 (en) * | 2015-04-24 | 2016-10-27 | University Of Louisville Research Foundation, Inc. | Selective pfkfb4 inhibitors for the treatment of cancer |
WO2018161039A1 (en) * | 2017-03-03 | 2018-09-07 | Synovo Gmbh | Novel anti-infective and anti-inflammatory compounds |
AU2018324043A1 (en) | 2017-08-31 | 2020-04-02 | University Of Louisville Research Foundation, Inc. | Quinoline derivative, compositions comprising this compound and uses thereof in the treatment of cancer |
US10774046B2 (en) | 2017-10-26 | 2020-09-15 | University Of Louisville Research Foundation, Inc. | Inhibitors for the treatment of cancer and related methods |
RU2709067C1 (ru) * | 2018-07-23 | 2019-12-13 | федеральное государственное бюджетное образовательное учреждение высшего образования "Тольяттинский государственный университет" | Способ термосиловой обработки длинномерных осесимметричных деталей и устройство для его осуществления |
EP4181912A1 (en) | 2020-07-15 | 2023-05-24 | Schabar Research Associates LLC | Unit oral dose compositions composed of ibuprofen and famotidine for the treatment of acute pain and the reduction of the severity and/or risk of heartburn |
CA3124579A1 (en) | 2020-07-15 | 2022-01-15 | Schabar Research Associates Llc | Unit oral dose compositions composed of naproxen sodium and famotidine for the treatment of acute pain and the reduction of the severity of heartburn and/or the risk of heartburn |
CN112316158B (zh) * | 2020-11-19 | 2021-09-21 | 四川大学 | 一种利用超分子包合剂关闭胶原溶液中抗菌剂活性的方法 |
CN114557983B (zh) * | 2022-03-18 | 2022-12-27 | 北京诺和德美医药科技有限公司 | 一种稳定的吸入用盐酸溴己新溶液及其制备方法 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2805404A1 (de) * | 1978-02-09 | 1979-08-16 | Merck Patent Gmbh | 1-aryloxy-3-nitratoalkylamino-2-propanole und verfahren zu ihrer herstellung |
ATE2269T1 (de) | 1978-12-21 | 1983-02-15 | Gruppo Lepetit S.P.A. | 3h-naphtho(1,2-d)imidazole, verfahren zu deren herstellung, verbindungen zur verwendung als entzuendungshemmende und antimikrobielle mittel und sie enthaltende zusammensetzungen zu dieser verwendung. |
IT1256345B (it) * | 1992-08-20 | 1995-12-01 | Esteri nitrici di derivati dell'acido 2-(2,6-di-alo-fenilammino) fenilacetico e procedimento per la loro preparazione | |
IT1256450B (it) | 1992-11-26 | 1995-12-05 | Soldato Piero Del | Esteri nitrici con attivita' farmacologica e procedimento per la loro preparazione |
ATE168986T1 (de) * | 1993-10-06 | 1998-08-15 | Nicox Sa | Salzetersaüreester mit entzündungshemmender und/oder schmerzlindernder wirkung und verfahren zu deren herstellung |
KR100387359B1 (ko) * | 1994-05-10 | 2003-08-27 | 니콕스 에스. 에이. | 항-염증성,비알러지성및항-혈전성을가지는니트로화합물들과그들의조성물들 |
JPH09202764A (ja) * | 1996-01-24 | 1997-08-05 | Chugai Pharmaceut Co Ltd | ニトロ化合物 |
IT1285770B1 (it) | 1996-10-04 | 1998-06-18 | Nicox Sa | Composti corticoidei |
IT1295694B1 (it) | 1996-11-14 | 1999-05-27 | Nicox Sa | Nitrossi derivati per la preparazione di medicamenti ad attivita antitrombinica |
IT1311923B1 (it) * | 1999-04-13 | 2002-03-20 | Nicox Sa | Composti farmaceutici. |
IT1314184B1 (it) * | 1999-08-12 | 2002-12-06 | Nicox Sa | Composizioni farmaceutiche per la terapia di condizioni di stressossidativo |
-
1999
- 1999-08-12 IT IT1999MI001817A patent/IT1314184B1/it active
-
2000
- 2000-07-27 MX MXPA02001519A patent/MXPA02001519A/es active IP Right Grant
- 2000-07-27 IL IL14780100A patent/IL147801A0/xx not_active IP Right Cessation
- 2000-07-27 JP JP2001516885A patent/JP2003515526A/ja not_active Ceased
- 2000-07-27 DK DK00953102T patent/DK1252133T3/da active
- 2000-07-27 DE DE60020741T patent/DE60020741T2/de not_active Expired - Lifetime
- 2000-07-27 CA CA002381409A patent/CA2381409A1/en not_active Abandoned
- 2000-07-27 BR BR0013264-0A patent/BR0013264A/pt active Search and Examination
- 2000-07-27 NZ NZ535559A patent/NZ535559A/en not_active IP Right Cessation
- 2000-07-27 EP EP05104064A patent/EP1593664A1/en not_active Withdrawn
- 2000-07-27 ES ES00953102T patent/ES2243292T3/es not_active Expired - Lifetime
- 2000-07-27 PT PT00953102T patent/PT1252133E/pt unknown
- 2000-07-27 AU AU65670/00A patent/AU781643B2/en not_active Ceased
- 2000-07-27 NZ NZ516889A patent/NZ516889A/en not_active IP Right Cessation
- 2000-07-27 EP EP00953102A patent/EP1252133B1/en not_active Expired - Lifetime
- 2000-07-27 KR KR1020067024051A patent/KR100760394B1/ko not_active IP Right Cessation
- 2000-07-27 KR KR1020027001883A patent/KR100687809B1/ko not_active IP Right Cessation
- 2000-07-27 HU HU0203939A patent/HUP0203939A3/hu unknown
- 2000-07-27 AT AT00953102T patent/ATE297375T1/de not_active IP Right Cessation
- 2000-07-27 RU RU2002103509/04A patent/RU2264383C2/ru not_active IP Right Cessation
- 2000-07-27 PL PL353451A patent/PL203200B1/pl not_active IP Right Cessation
- 2000-07-27 CN CNB2006101362310A patent/CN100528834C/zh not_active Expired - Fee Related
- 2000-07-27 CA CA2698353A patent/CA2698353A1/en not_active Abandoned
- 2000-07-27 WO PCT/EP2000/007225 patent/WO2001012584A2/en active IP Right Grant
- 2000-07-27 US US10/048,469 patent/US7186753B1/en not_active Expired - Fee Related
- 2000-07-27 CN CNB008140499A patent/CN1289466C/zh not_active Expired - Fee Related
-
2002
- 2002-01-23 ZA ZA200200628A patent/ZA200200628B/xx unknown
- 2002-02-08 NO NO20020623A patent/NO328498B1/no not_active IP Right Cessation
-
2006
- 2006-12-21 US US11/642,783 patent/US7399878B2/en not_active Expired - Fee Related
-
2008
- 2008-06-03 US US12/132,245 patent/US7759392B2/en not_active Expired - Fee Related
-
2009
- 2009-10-29 NO NO20093253A patent/NO20093253L/no unknown
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
IT1314184B1 (it) | Composizioni farmaceutiche per la terapia di condizioni di stressossidativo | |
NO20014925L (no) | Farmasöytiske forbindelser | |
ES2149305T3 (es) | Compuestos de dibenzoxazepina sustituidos, composiciones farmaceuticas y procedimientos de uso. | |
ES2115600T3 (es) | Derivados de 1-metilcarbapenem y procedimiento para su preparacion. | |
ATE153337T1 (de) | Thienopyridinderivate und diese enthaltende pharmazeutische zubereitungen | |
TW243449B (it) | ||
DE69707372T2 (de) | Verwendung eines Phosphorsäurediesters zur Herstellung eines Arzneimittels zur Behandlung von Akne | |
DE69921151D1 (de) | Fluorszierende marker | |
EA200100916A1 (ru) | Лекарственное средство, содержащее производное сульфопиранозилацилглицерина | |
NO982873D0 (no) | 1-metylkarbapenemderivater | |
NO985202D0 (no) | Anti-heliobacter pylori-preparater inneholdende 1-metylcarbapenemderivater | |
DE69200365D1 (de) | Pharmazeutische Zusammensetzung zur Verbesserung von Dysuria. | |
WO2000027378A3 (en) | Cystine derivatives as therapeutic agents for matrix metalloprotease related diseases |