|
US20040014761A1
(en)
*
|
1997-10-28 |
2004-01-22 |
Place Virgil A. |
Treatment of female sexual dysfunction with phosphodiesterase inhibitors
|
|
US6403597B1
(en)
*
|
1997-10-28 |
2002-06-11 |
Vivus, Inc. |
Administration of phosphodiesterase inhibitors for the treatment of premature ejaculation
|
|
HU230154B1
(hu)
*
|
1997-11-12 |
2015-09-28 |
Bayer Intellectual Property Gmbh |
Eljárás 2-es helyzetben fenil-szubszituenst hordozó imidazo-triazinon-származékok előállítására
|
|
DE19827640A1
(de)
*
|
1998-06-20 |
1999-12-23 |
Bayer Ag |
7-Alkyl- und Cycloalkyl-substituierte Imidazotriazinone
|
|
US7235625B2
(en)
|
1999-06-29 |
2007-06-26 |
Palatin Technologies, Inc. |
Multiple agent therapy for sexual dysfunction
|
|
DE19944161A1
(de)
*
|
1999-09-15 |
2001-03-22 |
Bayer Ag |
Neue Kombination zur Behandlung von sexueller Dysfunktion
|
|
CA2323008C
(en)
*
|
1999-10-11 |
2005-07-12 |
Pfizer Inc. |
Pharmaceutically active compounds
|
|
US20040254153A1
(en)
*
|
1999-11-08 |
2004-12-16 |
Pfizer Inc |
Compounds for the treatment of female sexual dysfunction
|
|
IL139455A0
(en)
*
|
1999-11-08 |
2001-11-25 |
Pfizer |
Compounds for the treatment of female sexual dysfunction
|
|
CA2395418A1
(en)
|
1999-12-24 |
2001-07-05 |
Bayer Aktiengesellschaft |
Isoxazolo pyrimidinones and the use thereof
|
|
US6683081B2
(en)
|
1999-12-24 |
2004-01-27 |
Bayer Aktiengesellschaft |
Triazolotriazinones and the use thereof
|
|
WO2001047928A2
(de)
|
1999-12-24 |
2001-07-05 |
Bayer Aktiengesellschaft |
Imidazo 1,3,5 triazinone und ihre verwendung
|
|
DE10010067A1
(de)
*
|
2000-03-02 |
2001-09-06 |
Bayer Ag |
Neue Imidazotriazinone und ihre Verwendung
|
|
AU5584901A
(en)
|
2000-04-19 |
2001-10-30 |
Icos Corp |
Use of cyclic gmp-specific phosphodiesterase inhibitors for treatment of parkinson's disease
|
|
US6821978B2
(en)
*
|
2000-09-19 |
2004-11-23 |
Schering Corporation |
Xanthine phosphodiesterase V inhibitors
|
|
BR0114321A
(pt)
*
|
2000-09-29 |
2003-07-01 |
Glaxo Group Ltd |
Composto, composição farmacêutica, uso de um composto, método de tratamento ou profilaxia de doenças inflamatórias, e, processo para preparar um composto
|
|
US6548508B2
(en)
|
2000-10-20 |
2003-04-15 |
Pfizer, Inc. |
Use of PDE V inhibitors for improved fecundity in mammals
|
|
US20020091129A1
(en)
*
|
2000-11-20 |
2002-07-11 |
Mitradev Boolell |
Treatment of premature ejaculation
|
|
DE10063106A1
(de)
*
|
2000-12-18 |
2002-06-20 |
Bayer Ag |
Verfahren zur Herstellung von 2-(2-Ethoxyphenyl)-substituierten Imidazotriazinonen
|
|
DE10063108A1
(de)
*
|
2000-12-18 |
2002-06-20 |
Bayer Ag |
Verfahren zur Herstellung von Sulfonamid-substituierten Imidazotriazinonen
|
|
DE10064105A1
(de)
*
|
2000-12-21 |
2002-06-27 |
Bayer Ag |
Neue Substituierte Imidazotriazinone
|
|
US6683080B2
(en)
|
2001-02-02 |
2004-01-27 |
Pfizer Inc. |
Treatment of diabetes mellitus
|
|
DE10107639A1
(de)
*
|
2001-02-15 |
2002-08-22 |
Bayer Ag |
2-Alkoxyphenyl-substituierte Imidazotriazinone
|
|
DE10108752A1
(de)
*
|
2001-02-23 |
2002-09-05 |
Bayer Ag |
Neue Substituierte Imidazotriazinone
|
|
GB0107751D0
(en)
*
|
2001-03-28 |
2001-05-16 |
Pfizer Ltd |
Pharmaceutically active compounds
|
|
DE10118306A1
(de)
*
|
2001-04-12 |
2002-10-17 |
Bayer Ag |
Imidazotriazinonhaltige Zusammensetzungen zur nasalen Applikation
|
|
WO2002089808A1
(de)
*
|
2001-05-09 |
2002-11-14 |
Bayer Healthcare Ag |
Neue verwendung von 2-phenyl-substituierten imidazotriazinonen
|
|
US20070122353A1
(en)
|
2001-05-24 |
2007-05-31 |
Hale Ron L |
Drug condensation aerosols and kits
|
|
US7585493B2
(en)
|
2001-05-24 |
2009-09-08 |
Alexza Pharmaceuticals, Inc. |
Thin-film drug delivery article and method of use
|
|
US7458374B2
(en)
|
2002-05-13 |
2008-12-02 |
Alexza Pharmaceuticals, Inc. |
Method and apparatus for vaporizing a compound
|
|
US7090830B2
(en)
|
2001-05-24 |
2006-08-15 |
Alexza Pharmaceuticals, Inc. |
Drug condensation aerosols and kits
|
|
US7766013B2
(en)
|
2001-06-05 |
2010-08-03 |
Alexza Pharmaceuticals, Inc. |
Aerosol generating method and device
|
|
US7087605B2
(en)
|
2001-06-01 |
2006-08-08 |
Bayer Aktiengesellschaft |
5-Ethyl-imidazotriazinones
|
|
GB0113344D0
(en)
|
2001-06-01 |
2001-07-25 |
Bayer Ag |
Novel heterocycles 3
|
|
DE10130167A1
(de)
*
|
2001-06-22 |
2003-01-02 |
Bayer Ag |
Imidazotriazine
|
|
DE10135815A1
(de)
*
|
2001-07-23 |
2003-02-06 |
Bayer Ag |
Verwendung von 2-Alkoxyphenyl-substituierten Imidazotriazinonen
|
|
CA2457944C
(en)
|
2001-08-28 |
2009-09-29 |
Schering Corporation |
Polycyclic guanine phosphodiesterase v inhibitors
|
|
JP2005509038A
(ja)
*
|
2001-11-09 |
2005-04-07 |
シェーリング コーポレイション |
多環式グアニン誘導体ホスホジエステラーゼv阻害剤
|
|
GB0129274D0
(en)
*
|
2001-12-06 |
2002-01-23 |
Pfizer Ltd |
Novel kit
|
|
HU228316B1
(en)
*
|
2001-12-13 |
2013-03-28 |
Daiichi Sankyo Company |
Pyrazolopyrimidinone derivatives having pde7-inhibitory activity
|
|
GB0130219D0
(en)
*
|
2001-12-18 |
2002-02-06 |
Pfizer Ltd |
Compounds for the treatment of sexual dysfunction
|
|
GB0209988D0
(en)
*
|
2002-05-01 |
2002-06-12 |
Bayer Ag |
Novel Heterocycles
|
|
DE10220570A1
(de)
|
2002-05-08 |
2003-11-20 |
Bayer Ag |
Carbamat-substituierte Pyrazolopyridine
|
|
US7091207B2
(en)
|
2002-05-22 |
2006-08-15 |
Virginia Commonwealth University |
Method of treating myocardial infarction with PDE-5 inhibitors
|
|
BR0311191A
(pt)
*
|
2002-05-23 |
2005-03-01 |
Pfizer |
Combinação
|
|
SI1509525T1
(sl)
|
2002-05-31 |
2006-12-31 |
Schering Corp |
Postopek priprave inhibitorjev ksantinske fosfodiesteraze V in njihovih prekurzorjev
|
|
GB0214784D0
(en)
*
|
2002-06-26 |
2002-08-07 |
Pfizer Ltd |
Novel combination
|
|
DE10229778A1
(de)
*
|
2002-07-03 |
2004-01-29 |
Bayer Ag |
Neue Verwendung von Imidazotriazinonen
|
|
DE10230605A1
(de)
|
2002-07-08 |
2004-01-29 |
Bayer Ag |
Substituierte Imidazotriazine
|
|
DE10232113A1
(de)
*
|
2002-07-16 |
2004-01-29 |
Bayer Ag |
Vardenafil Hydrochlorid Trihydrat enthaltende Arzneimittel
|
|
GB0219961D0
(en)
|
2002-08-28 |
2002-10-02 |
Pfizer Ltd |
Oxytocin inhibitors
|
|
US7323462B2
(en)
|
2002-12-10 |
2008-01-29 |
Pfizer Inc. |
Morpholine dopamine agonists
|
|
EP1572173B1
(en)
|
2002-12-13 |
2010-04-28 |
Warner-Lambert Company LLC |
Alpha-2-delta ligand to treat lower urinary tract symptoms
|
|
EP1608656B1
(en)
|
2003-04-01 |
2009-06-03 |
SmithKline Beecham Corporation |
Imidazotriazine compounds for the treatment of cancer diseases
|
|
MXPA05011643A
(es)
|
2003-04-29 |
2005-12-15 |
Pfizer Ltd |
5,7-diaminopirazolo[4,3-d]pirimidinas en el tratamiento de hipertension.
|
|
US20040220186A1
(en)
*
|
2003-04-30 |
2004-11-04 |
Pfizer Inc. |
PDE9 inhibitors for treating type 2 diabetes,metabolic syndrome, and cardiovascular disease
|
|
WO2004104491A2
(en)
|
2003-05-21 |
2004-12-02 |
Alexza Pharmaceuticals, Inc. |
Percussively ignited or electrically ignited self-contained heating unit and drug-supply unit employing same
|
|
US20060094723A1
(en)
|
2003-05-22 |
2006-05-04 |
Torsten Dunkern |
Composition comprising a pde4 inhibitor and a pde5 inhibitor
|
|
CN100374441C
(zh)
|
2003-06-06 |
2008-03-12 |
天津倍方科技发展有限公司 |
二氢吡咯[2,3-d]嘧啶-4-酮衍生物,其制备方法及其制药用途
|
|
JP2006219374A
(ja)
*
|
2003-06-13 |
2006-08-24 |
Daiichi Asubio Pharma Co Ltd |
Pde7阻害作用を有するイミダゾトリアジノン誘導体
|
|
US20050079548A1
(en)
*
|
2003-07-07 |
2005-04-14 |
Plexxikon, Inc. |
Ligand development using PDE4B crystal structures
|
|
US7291640B2
(en)
*
|
2003-09-22 |
2007-11-06 |
Pfizer Inc. |
Substituted triazole derivatives as oxytocin antagonists
|
|
JP2007512345A
(ja)
*
|
2003-11-21 |
2007-05-17 |
シェーリング コーポレイション |
ホスホジエステラーゼv阻害剤処方物
|
|
US7572799B2
(en)
*
|
2003-11-24 |
2009-08-11 |
Pfizer Inc |
Pyrazolo[4,3-d]pyrimidines as Phosphodiesterase Inhibitors
|
|
GB0327323D0
(en)
*
|
2003-11-24 |
2003-12-31 |
Pfizer Ltd |
Novel pharmaceuticals
|
|
JP2007518788A
(ja)
|
2004-01-22 |
2007-07-12 |
ファイザー・インク |
バソプレッシンのアンタゴニスト活性を阻害するトリアゾール誘導体
|
|
US7569572B2
(en)
*
|
2004-04-07 |
2009-08-04 |
Pfizer Inc |
Pyrazolo[4,3-D]pyrimidines
|
|
DE102004023069A1
(de)
*
|
2004-05-11 |
2005-12-08 |
Bayer Healthcare Ag |
Neue Darreichungsformen des PDE 5-Inhibitors Vardenafil
|
|
US7540286B2
(en)
|
2004-06-03 |
2009-06-02 |
Alexza Pharmaceuticals, Inc. |
Multiple dose condensation aerosol devices and methods of forming condensation aerosols
|
|
JP2008501617A
(ja)
*
|
2004-06-11 |
2008-01-24 |
アスビオファーマ株式会社 |
Pde7阻害作用を有するイミダゾトリアジノン誘導体
|
|
CA2576961A1
(en)
|
2004-08-12 |
2006-03-02 |
Alexza Pharmaceuticals, Inc. |
Aerosol drug delivery device incorporating percussively activated heat packages
|
|
DE102005001989A1
(de)
*
|
2005-01-15 |
2006-07-20 |
Bayer Healthcare Ag |
Intravenöse Formulierungen von PDE-Inhibitoren
|
|
CN102351862A
(zh)
*
|
2005-02-18 |
2012-02-15 |
表面线段公司 |
药动学改善的化合物
|
|
EP1848437A4
(en)
*
|
2005-02-18 |
2012-04-25 |
Surface Logix Inc |
METHOD FOR PRODUCING PHARMACOKINETIC IMPROVED COMPOUNDS WITH FUNCTIONAL RESTORATIONS OR GROUPS AND PHARMACEUTICAL COMPOSITIONS WITH THESE COMPOUNDS
|
|
DE102005009241A1
(de)
|
2005-03-01 |
2006-09-07 |
Bayer Healthcare Ag |
Arzneiformen mit kontrollierter Bioverfügbarkeit
|
|
DE102005009240A1
(de)
*
|
2005-03-01 |
2006-09-07 |
Bayer Healthcare Ag |
Arzneiformen mit verbesserten pharmakokinetischen Eigenschaften
|
|
DE102005016345A1
(de)
*
|
2005-04-09 |
2006-10-12 |
Bayer Healthcare Ag |
Neue Verwendung von 2-Phenyl-substituierten Imidazotriazinon-Derivaten
|
|
MX2007012711A
(es)
|
2005-04-19 |
2008-01-11 |
Nycomed Gmbh |
Roflumilast para el tratamiento de hipertension pulmonar.
|
|
EP1881985B1
(en)
|
2005-05-12 |
2010-12-29 |
Pfizer, Inc. |
Anhydrous crystalline forms of n-ý1-(2-ethoxyethyl)-5-(n-ethyl-n-methylamino)-7-(4-methylpyridin-2-yl-amino)-1h-pyrazolo[4,3-d]pyrimidine-3-carbonyl¨methanesulfonamide
|
|
WO2006127368A2
(en)
*
|
2005-05-20 |
2006-11-30 |
Lexicon Genetics Incorporated |
Methods for synthesizing imidazotriazinones
|
|
US20070010525A1
(en)
*
|
2005-06-27 |
2007-01-11 |
Meyer Jackson |
Method and compositions for modulating neuropeptide hormone secretion
|
|
CA2618103A1
(en)
*
|
2005-08-10 |
2007-02-15 |
Pfizer Limited |
Substituted triazole derivatives as oxytocin antagonists
|
|
EP2258357A3
(en)
|
2005-08-26 |
2011-04-06 |
Braincells, Inc. |
Neurogenesis with acetylcholinesterase inhibitor
|
|
EP2275096A3
(en)
|
2005-08-26 |
2011-07-13 |
Braincells, Inc. |
Neurogenesis via modulation of the muscarinic receptors
|
|
SG166106A1
(en)
*
|
2005-09-29 |
2010-11-29 |
Bayer Schering Pharma Ag |
Pde inhibitors and combinations thereof for the treatment of urological disorders
|
|
WO2007047282A1
(en)
*
|
2005-10-12 |
2007-04-26 |
Lilly Icos Llc |
Treatment of benign prostatic hypertrophy and lower urinary tract symptoms
|
|
EP1940389A2
(en)
|
2005-10-21 |
2008-07-09 |
Braincells, Inc. |
Modulation of neurogenesis by pde inhibition
|
|
US20070112017A1
(en)
|
2005-10-31 |
2007-05-17 |
Braincells, Inc. |
Gaba receptor mediated modulation of neurogenesis
|
|
GB0601951D0
(en)
|
2006-01-31 |
2006-03-15 |
Novartis Ag |
Organic compounds
|
|
CN101415670A
(zh)
*
|
2006-02-17 |
2009-04-22 |
惠氏公司 |
制备磺酰胺取代醇和其中间体的方法
|
|
RU2008131051A
(ru)
*
|
2006-02-17 |
2010-03-27 |
Вайет (Us) |
Избирательное n-сульфонилирование 2-амино трифторалкильнзамещенных спиртов
|
|
US20100216734A1
(en)
|
2006-03-08 |
2010-08-26 |
Braincells, Inc. |
Modulation of neurogenesis by nootropic agents
|
|
US7977478B2
(en)
*
|
2006-03-13 |
2011-07-12 |
Dr. Reddy's Laboratories Limited |
Polymorphic forms of vardenafil
|
|
EP3693363A1
(en)
*
|
2006-03-17 |
2020-08-12 |
The Johns Hopkins University |
N-hydroxylsulfonamide derivatives as new physiologically useful nitroxyl donors
|
|
WO2007124045A2
(en)
*
|
2006-04-20 |
2007-11-01 |
Ampla Pharmaceuticals, Inc. |
Piperidine and piperazine compounds for use in the treatment of obesity, eating disorders and sexual dysfunction by potentiation of mc4 receptor activity
|
|
CA2651862A1
(en)
|
2006-05-09 |
2007-11-22 |
Braincells, Inc. |
5 ht receptor mediated neurogenesis
|
|
AU2007249399A1
(en)
|
2006-05-09 |
2007-11-22 |
Braincells, Inc. |
Neurogenesis by modulating angiotensin
|
|
DE602007003024D1
(de)
|
2006-06-27 |
2009-12-10 |
Sandoz Ag |
Neues verfahren zur salzherstellung
|
|
US20090298878A1
(en)
*
|
2006-07-14 |
2009-12-03 |
Akira Matsumura |
Oxime compounds and the use thereof
|
|
WO2008024494A2
(en)
*
|
2006-08-24 |
2008-02-28 |
Surface Logix, Inc. |
Pharmacokinetically improved compounds
|
|
AR062501A1
(es)
|
2006-08-29 |
2008-11-12 |
Actelion Pharmaceuticals Ltd |
Composiciones terapeuticas
|
|
WO2008030651A1
(en)
|
2006-09-08 |
2008-03-13 |
Braincells, Inc. |
Combinations containing a 4-acylaminopyridine derivative
|
|
DE102006043443A1
(de)
*
|
2006-09-15 |
2008-03-27 |
Bayer Healthcare Ag |
Neue aza-bicyclische Verbindungen und ihre Verwendung
|
|
US20100184806A1
(en)
|
2006-09-19 |
2010-07-22 |
Braincells, Inc. |
Modulation of neurogenesis by ppar agents
|
|
US8314119B2
(en)
*
|
2006-11-06 |
2012-11-20 |
Abbvie Inc. |
Azaadamantane derivatives and methods of use
|
|
HUE025355T2
(en)
|
2006-12-12 |
2016-02-29 |
Gilead Sciences Inc |
Composition for treating pulmonary hypertension
|
|
CN101674728A
(zh)
|
2007-02-12 |
2010-03-17 |
Dmi生物科学公司 |
降低曲马多的副作用
|
|
US20080194529A1
(en)
*
|
2007-02-12 |
2008-08-14 |
Auspex Pharmaceuticals, Inc. |
HIGHLY SELECTIVE and LONG-ACTING PDE5 MODULATORS
|
|
ES2384481T3
(es)
|
2007-02-12 |
2012-07-05 |
Dmi Biosciences, Inc. |
Tratamiento de la eyaculación precoz y la disfunción eréctil co-morbidas
|
|
ES2594867T3
(es)
|
2007-03-09 |
2016-12-23 |
Alexza Pharmaceuticals, Inc. |
Unidad de calentamiento para usar en un dispositivo de administración de fármaco
|
|
DE102007027067A1
(de)
|
2007-06-12 |
2008-12-18 |
Ratiopharm Gmbh |
Verfahren zur Herstellung eines Arzneimittels enthaltend Vardenafil Hydrochlorid Trihydrat
|
|
KR20100029762A
(ko)
*
|
2007-06-13 |
2010-03-17 |
바이엘 쉐링 파마 악티엔게젤샤프트 |
청력 장애 치료용 pde 억제제
|
|
CN101965348B
(zh)
*
|
2007-09-06 |
2013-11-13 |
上海特化医药科技有限公司 |
伐地那非的制备方法及其中间体
|
|
EP2228370B1
(en)
|
2007-12-28 |
2012-05-23 |
Topharman Shanghai Co., Ltd. |
N-{1-[3-(2-ethoxy-5-(4-ethylpiperazinyl)benzenesulfonyl)-4,5-dihydro-5-oxo-1,2,4-triazin-6-yl]ethyl}butyramide, the preparation method and use thereof
|
|
WO2009091777A1
(en)
*
|
2008-01-15 |
2009-07-23 |
Forest Laboratories Holdings Limited |
Nebivolol in the treatment of sexual dysfunction
|
|
DE102008063992A1
(de)
|
2008-12-19 |
2010-09-02 |
Lerner, Zinoviy, Dipl.-Ing. |
Neue aliphatisch substituierte Pyrazolopyridine und ihre Verwendung
|
|
EP2379076B1
(en)
|
2008-12-23 |
2014-11-12 |
The Trustees of Columbia University in the City of New York |
Phosphodiesterase inhibitors and uses thereof
|
|
WO2010099217A1
(en)
|
2009-02-25 |
2010-09-02 |
Braincells, Inc. |
Modulation of neurogenesis using d-cycloserine combinations
|
|
GB0903493D0
(en)
|
2009-02-27 |
2009-04-08 |
Vantia Ltd |
New compounds
|
|
DE102009020888A1
(de)
|
2009-05-12 |
2010-11-18 |
Ratiopharm Gmbh |
Schmelztablette, enthaltend ein Vardenafil-Salz
|
|
EP2462127A1
(en)
|
2009-08-07 |
2012-06-13 |
Ranbaxy Laboratories Limited |
Processes for the preparation of vardenafil
|
|
EA036422B1
(ru)
|
2009-11-27 |
2020-11-09 |
Адверио Фарма Гмбх |
Способ получения метил-{4,6-диамино-2-[1-(2-фторбензил)-1h-пиразоло[3,4-b]пиридин-3-ил]пиримидин-5-ил}метилкарбамата
|
|
UY33041A
(es)
|
2009-11-27 |
2011-06-30 |
Bayer Schering Pharma Aktienegesellschaft |
Procedimiento para la preparaciòn de {4,6-diamino-2-[1-(2-fluorobencil)-1h-pirazolo[3,4-b]piridin-3-il]pirimidin-5-il}carbamato de metilo y su purificaciòn para el uso como principio activo farmacèutico
|
|
EP2517705B1
(en)
|
2009-12-21 |
2016-10-19 |
Acef S/A |
Cubebin as vasodilating agent in the therapy of erectile dysfunction
|
|
PL390079A1
(pl)
*
|
2009-12-30 |
2011-07-04 |
Zakłady Farmaceutyczne POLPHARMA Spółka Akcyjna |
Sposób otrzymywania wardenafilu i jego izolacji jako soli z kwasem cytrynowym oraz krystaliczna postać tej soli
|
|
CN102970965A
(zh)
|
2010-04-05 |
2013-03-13 |
Sk化学公司 |
含有pde5抑制剂的减少皮肤皱纹的合成物
|
|
DE102010021637A1
(de)
|
2010-05-26 |
2011-12-01 |
Bayer Schering Pharma Aktiengesellschaft |
Substituierte 5-Fluor-1H-Pyrazolopyridine und ihre Verwendung
|
|
CN102382129B
(zh)
*
|
2010-08-19 |
2014-02-26 |
山东轩竹医药科技有限公司 |
螺环取代的磷酸二酯酶抑制剂
|
|
CN102372730B
(zh)
*
|
2010-08-19 |
2014-03-26 |
山东轩竹医药科技有限公司 |
桥环取代的磷酸二酯酶抑制剂
|
|
WO2012040230A1
(en)
|
2010-09-20 |
2012-03-29 |
Envivo Pharmaceuticals, Inc. |
Imidazotriazinone compounds
|
|
UA110802C2
(uk)
|
2010-09-23 |
2016-02-25 |
Еббві Бахамаз Лтд. |
Моногідрат похідного азаадамантану
|
|
EP3106163A1
(en)
|
2010-10-15 |
2016-12-21 |
Gilead Sciences, Inc. |
Compositions and methods of treating pulmonary hypertension
|
|
TWI462739B
(zh)
|
2010-11-02 |
2014-12-01 |
Univ Kaohsiung Medical |
Sildenafil-同族物四級銨哌嗪鹽類之製備及醫療用途
|
|
CN102134242B
(zh)
|
2011-01-21 |
2013-08-28 |
浙江大德药业集团有限公司 |
一种用于治疗阳痿的快速长效的化合物
|
|
HK1211023A1
(zh)
|
2011-10-10 |
2016-05-13 |
H. Lundbeck A/S |
具有咪唑并吡嗪骨架pde9i
|
|
AT512084A1
(de)
*
|
2011-10-20 |
2013-05-15 |
Univ Wien Tech |
Diazabicyclo- und diazaspiro-alkanderivate als phosphodiesterase-5 inhibitoren
|
|
WO2013067309A1
(en)
|
2011-11-04 |
2013-05-10 |
Xion Pharmaceutical Corporation |
Methods and compositions for oral administration of melanocortin receptor agonist compounds
|
|
CZ2011767A3
(cs)
*
|
2011-11-24 |
2013-06-05 |
Zentiva, K.S. |
Zpusob prípravy a izolace solí vardenafilu s kyselinami
|
|
US20150119399A1
(en)
|
2012-01-10 |
2015-04-30 |
President And Fellows Of Harvard College |
Beta-cell replication promoting compounds and methods of their use
|
|
WO2013109738A1
(en)
|
2012-01-17 |
2013-07-25 |
The Trustees Of Columbia University In The City Of New York |
Novel phosphodiesterase inhibitors and uses thereof
|
|
CN104093720B
(zh)
|
2012-01-26 |
2017-04-12 |
H.隆德贝克有限公司 |
具有咪唑并三嗪酮骨架的pde9抑制剂
|
|
IN2014MN01706A
(cs)
|
2012-02-28 |
2015-05-29 |
Seoul Pharma Co Ltd |
|
|
HK1206726A1
(en)
|
2012-03-19 |
2016-01-15 |
Ironwood Pharmaceuticals, Inc. |
Imidazotriazinone compounds
|
|
CN103374002B
(zh)
*
|
2012-04-19 |
2015-07-15 |
山东轩竹医药科技有限公司 |
磷酸二酯酶-5抑制剂
|
|
CZ307091B6
(cs)
|
2012-09-14 |
2018-01-10 |
Zentiva, K.S. |
Stabilní farmaceutický přípravek obsahující Vardenafil hydrochlorid
|
|
ES2903151T3
(es)
|
2012-12-04 |
2022-03-31 |
Aribio Inc |
Composición que comprende inhibidor de fosfodiesterasa tipo 5 para inhibir la apoptosis de células nerviosas
|
|
KR101953735B1
(ko)
|
2012-12-14 |
2019-03-04 |
한미약품 주식회사 |
포스포다이에스터라제-5 억제제를 포함하는 츄정
|
|
CN105102457A
(zh)
|
2013-02-21 |
2015-11-25 |
阿德弗里奥药品有限责任公司 |
{4,6-二氨基-2-[1-(2-氟苄基)-1H-吡唑并[3,4-b]吡啶-3-基]嘧啶-5-基}甲基氨基甲酸甲酯的形式
|
|
CN104109164B
(zh)
*
|
2013-04-18 |
2016-05-25 |
广州朗圣药业有限公司 |
一种适合工业化的高纯度盐酸伐地那非三水合物的制备方法
|
|
US10899756B2
(en)
|
2013-07-17 |
2021-01-26 |
The Trustees Of Columbia University In The City Of New York |
Phosphodiesterase inhibitors and uses thereof
|
|
US20160317542A1
(en)
|
2013-12-09 |
2016-11-03 |
Respira Therapeutics, Inc. |
Pde5 inhibitor powder formulations and methods relating thereto
|
|
PL223869B1
(pl)
*
|
2013-12-16 |
2016-11-30 |
Starogardzkie Zakłady Farm Polpharma Spółka Akcyjna |
Sposób otrzymywania wardenafilu i jego soli
|
|
KR101645652B1
(ko)
|
2014-11-03 |
2016-08-08 |
(주)퓨젠바이오농업회사법인 |
세리포리아 락세라타에 의해 생산되는 세포외다당체를 유효성분으로 함유하는 성기능개선용 조성물
|
|
EP4335497A3
(en)
|
2015-07-07 |
2024-05-01 |
H. Lundbeck A/S |
Pde9 inhibitor with imidazo pyrazinone backbone for treatment of peripheral diseases
|
|
KR102862562B1
(ko)
*
|
2015-11-16 |
2025-09-19 |
토파두르 파마 아게 |
포스포디에스테라제 억제제로서 2-페닐-3,4-디하이드로피롤로[2,1-f][1,2,4]트리아지논 유도체 및 이의 용도
|
|
WO2017168174A1
(en)
|
2016-04-02 |
2017-10-05 |
N4 Pharma Uk Limited |
New pharmaceutical forms of sildenafil
|
|
CN110381951A
(zh)
|
2016-12-14 |
2019-10-25 |
瑞必治公司 |
用于治疗肺性高血压和其他肺病症的方法及组合物
|
|
AU2018274599B9
(en)
|
2017-05-22 |
2022-04-07 |
Topadur Pharma Ag |
Novel dual mode of action soluble guanylate cyclase activators and phosphodiesterase inhibitors and uses thereof
|
|
CN107445964A
(zh)
*
|
2017-07-29 |
2017-12-08 |
合肥创新医药技术有限公司 |
一种盐酸伐地那非杂质的合成方法
|
|
US20200330470A1
(en)
|
2017-12-20 |
2020-10-22 |
Klaria Pharma Holding Ab |
Film formulation comprising vardenafil, method for its preparation, and use thereof
|
|
WO2019152873A1
(en)
|
2018-02-02 |
2019-08-08 |
Alexza Pharmaceuticals, Inc. |
Electrical condensation aerosol device
|
|
CN117843645A
(zh)
|
2018-05-25 |
2024-04-09 |
伊马拉公司 |
一种pde9抑制剂的一水合物和结晶形态
|
|
CA3103716A1
(en)
|
2018-06-14 |
2019-12-19 |
Astrazeneca Uk Limited |
Methods for treating erectile dysfunction with a cgmp-specific phosphodiesterase 5 inhibitor pharmaceutical composition
|
|
AU2019287546A1
(en)
|
2018-06-14 |
2021-01-21 |
Astrazeneca Uk Limited |
Methods for treating erectile dysfunction with a cGMP-specific phosphodiesterase 5 inhibitor pharmaceutical composition
|
|
EP3843737A4
(en)
|
2018-08-31 |
2022-06-01 |
Imara Inc. |
PDE9 INHIBITORS FOR THE TREATMENT OF SICKLE CELL DISEASE
|
|
US20220031704A1
(en)
*
|
2018-11-28 |
2022-02-03 |
Topadur Pharma Ag |
Novel dual mode of action soluble guanylate cyclase activators and phosphodiesterase inhibitors and uses thereof
|
|
CA3132953A1
(en)
|
2019-03-13 |
2020-09-17 |
Otsuka Pharmaceutical Co., Ltd. |
Method for introducing deuterated lower alkyl into amine moiety of compound containing secondary amine
|
|
US11590209B2
(en)
|
2020-01-21 |
2023-02-28 |
Palatin Technologies, Inc. |
Use of bremelanotide in patients with controlled hypertension
|
|
WO2021245192A1
(en)
|
2020-06-04 |
2021-12-09 |
Topadur Pharma Ag |
Novel dual mode of action soluble guanylate cyclase activators and phosphodiesterase inhibitors and uses thereof
|
|
WO2022123310A1
(en)
*
|
2020-12-11 |
2022-06-16 |
Ildong Pharmaceutical Co., Ltd. |
Novel compounds as androgen receptor and phosphodiesterase dual inhibitor
|
|
AU2022263070B2
(en)
*
|
2021-04-21 |
2025-07-17 |
Changchun Genescience Pharmaceutical Co., Ltd. |
Imidazole-containing condensed ring derivative, preparation method therefor, and application thereof in medicine
|
|
CN114085225A
(zh)
*
|
2021-06-04 |
2022-02-25 |
广东西捷药业有限公司 |
一种伐地那非类似物及其合成方法和应用
|
|
AU2022354094A1
(en)
|
2021-09-29 |
2024-02-15 |
Topadur Pharma Ag |
Topical compositions of 2-phenyl-3,4-dihydropyrrolo[2,l-f] [1,2,4]triazinone derivatives and uses thereof
|
|
AU2023227111A1
(en)
|
2022-03-02 |
2024-07-25 |
Topadur Pharma Ag |
Topical compositions and uses therof
|
|
KR20230129639A
(ko)
|
2022-03-02 |
2023-09-11 |
연세대학교 산학협력단 |
이중작용 pde5 억제제/질산유기에스터의 국소 혈류 증진을 위한 경피 투약 형태
|
|
AU2024220563A1
(en)
|
2023-02-16 |
2025-08-14 |
University Of Rochester |
Improving glymphatic-lymphatic efflux
|