EP0828718A1
(en)
|
1995-06-02 |
1998-03-18 |
G.D. SEARLE & CO. |
Heterocyclo substituted hydroxamic acid derivatives as cyclooxygenase-2 and 5-lipoxygenase inhibitors
|
US5908858A
(en)
|
1996-04-05 |
1999-06-01 |
Sankyo Company, Limited |
1,2-diphenylpyrrole derivatives, their preparation and their therapeutic uses
|
EP0892791B1
(en)
*
|
1996-04-12 |
2003-03-05 |
G.D. Searle & Co. |
N-[[4-(5-METHYL-3-PHENYLISOXAZOL-4-YL]PHENYL]SULFONYLPROPYLAMIDE and its SODIUMSALT AS PRODRUGS OF COX-2 INHIBITORS
|
US8022095B2
(en)
|
1996-08-16 |
2011-09-20 |
Pozen, Inc. |
Methods of treating headaches using 5-HT agonists in combination with long-acting NSAIDs
|
US6586458B1
(en)
|
1996-08-16 |
2003-07-01 |
Pozen Inc. |
Methods of treating headaches using 5-HT agonists in combination with long-acting NSAIDs
|
EP0971714B1
(en)
*
|
1997-04-03 |
2002-10-09 |
G.D. Searle & Co. |
Method of using cyclooxygenase-2 inhibitors in the treatment and prevention of dementia
|
US20040072889A1
(en)
*
|
1997-04-21 |
2004-04-15 |
Pharmacia Corporation |
Method of using a COX-2 inhibitor and an alkylating-type antineoplastic agent as a combination therapy in the treatment of neoplasia
|
RS49982B
(sr)
|
1997-09-17 |
2008-09-29 |
Euro-Celtique S.A., |
Sinergistička analgetička kombinacija analgetičkog opijata i inhibitora ciklooksigenaze-2
|
NZ333399A
(en)
*
|
1997-12-24 |
2000-05-26 |
Sankyo Co |
Cyclooxygenase-2 inhibitors (COX-2) for the prevention and treatment of tumors, cachexia and tumor-metastasis
|
CA2322824A1
(en)
*
|
1998-03-13 |
1999-09-16 |
Merck & Co., Inc. |
Combination therapy and composition for acute coronary ischemic syndrome and related conditions
|
US6136804A
(en)
*
|
1998-03-13 |
2000-10-24 |
Merck & Co., Inc. |
Combination therapy for treating, preventing, or reducing the risks associated with acute coronary ischemic syndrome and related conditions
|
AU4428899A
(en)
|
1998-06-08 |
1999-12-30 |
Advanced Medicine, Inc. |
Multibinding inhibitors of cyclooxygenase-2
|
AR024222A1
(es)
*
|
1998-10-16 |
2002-09-25 |
Palau Pharma Sa |
Imidazoles con actividad antiinflamatoria un procedimiento para su preparacion y composiciones farmaceuticas que lo contienen
|
ES2234324T3
(es)
*
|
1998-11-02 |
2005-06-16 |
MERCK & CO., INC. |
Combinaciones de un agonista 5ht1b/1d y un inhibidor selectivo de cox-2 para el tratamiento de la migraña.
|
AU1398899A
(en)
*
|
1998-11-12 |
2000-06-05 |
Algos Pharmaceutical Corporation |
Cox-2 inhibitors in combination with centrally acting analgesics
|
US6649645B1
(en)
|
1998-12-23 |
2003-11-18 |
Pharmacia Corporation |
Combination therapy of radiation and a COX-2 inhibitor for treatment of neoplasia
|
US20030013739A1
(en)
*
|
1998-12-23 |
2003-01-16 |
Pharmacia Corporation |
Methods of using a combination of cyclooxygenase-2 selective inhibitors and thalidomide for the treatment of neoplasia
|
US20040122011A1
(en)
*
|
1998-12-23 |
2004-06-24 |
Pharmacia Corporation |
Method of using a COX-2 inhibitor and a TACE inhibitors as a combination therapy
|
US20030119895A1
(en)
*
|
1998-12-23 |
2003-06-26 |
Pharmacia Corporation |
Methods using a combination of a 3-heteroaryl-2-indolinone and a cyclooxygenase-2 inhibitor for the treatment of neoplasia
|
WO2000048583A2
(en)
*
|
1999-02-19 |
2000-08-24 |
Pozen Inc. |
Formulation of 5-ht agonists with nsaids, especially cox-2 inhibitors, for treating migraine
|
US20010024664A1
(en)
*
|
1999-03-19 |
2001-09-27 |
Obukowicz Mark G. |
Selective COX-2 inhibition from edible plant extracts
|
US6323226B1
(en)
|
1999-10-19 |
2001-11-27 |
Texas Heart Institute |
Treatment of heart disease with cox-2 inhibitors
|
KR100793668B1
(ko)
*
|
1999-12-08 |
2008-01-10 |
파마시아 코포레이션 |
강화된 생체이용률을 지닌 고체상 형태의 셀레콕시브
|
PT1239857E
(pt)
*
|
1999-12-22 |
2006-07-31 |
Pharmacia Corp |
Composicoes de libertacao dupla de um inibidor de ciclo-oxigenase-2
|
WO2001045703A1
(en)
|
1999-12-23 |
2001-06-28 |
Nitromed, Inc. |
Nitrosated and nitrosylated cyclooxygenase-2 inhibitors, compositions and methods of use
|
EP1296923B3
(en)
|
2000-02-16 |
2012-04-11 |
The Brigham And Women's Hospital, Inc. |
Aspirin-triggered lipid mediators
|
AU3217501A
(en)
*
|
2000-03-03 |
2001-09-12 |
Pfizer Prod Inc |
Pyrazole ether derivatives as anti-inflammatory/analgesic agents
|
US20070072861A1
(en)
*
|
2000-03-27 |
2007-03-29 |
Barbara Roniker |
Method of using cyclooxygenase-2 inhibitors in the prevention of cardiovascular disorders
|
ES2166710B1
(es)
*
|
2000-04-25 |
2004-10-16 |
J. URIACH & CIA, S.A. |
Nuevos compuestos heterociclicos con actividad antiinflamatoria.
|
WO2001081332A2
(en)
*
|
2000-04-25 |
2001-11-01 |
Pharmacia Corporation |
2-fluorobenzenesulfonyl compounds for the treatment of inflammation
|
WO2002005848A2
(en)
*
|
2000-07-13 |
2002-01-24 |
Pharmacia Corporation |
Use of cox-2 inhibitors in the treatment and prevention of ocular cox-2 mediated disorders
|
PT1303265E
(pt)
|
2000-07-20 |
2007-10-09 |
Lauras As |
''utilização de inibidores da cox-2 como imuno-estimulantes, no tratamento do vih ou da sida''
|
US20030219461A1
(en)
*
|
2000-09-12 |
2003-11-27 |
Britten Nancy J. |
Parenteral combination therapy for infective conditions
|
EP1322311A1
(en)
*
|
2000-09-18 |
2003-07-02 |
Merck & Co., Inc. |
Treatment of inflammation with a combination of a cyclooxygenase-2 inhibitor and an integrin alpha-v antagonist
|
AU2002213467A8
(en)
*
|
2000-10-11 |
2009-07-30 |
Chemocentryx Inc |
Modulation of ccr4 function
|
WO2002047707A2
(en)
*
|
2000-12-15 |
2002-06-20 |
Pharmacia Corporation |
Selective cox-2 inhibition from non-edible plant extracts
|
EP1401460A2
(en)
*
|
2000-12-15 |
2004-03-31 |
Pharmacia Corporation |
Selective cox-2 inhibition from plant extracts
|
CA2432642A1
(en)
|
2000-12-21 |
2002-08-08 |
Subhash P. Khanapure |
Substituted aryl compounds as novel cyclooxygenase-2 selective inhibitors, compositions and methods of use
|
US7115565B2
(en)
*
|
2001-01-18 |
2006-10-03 |
Pharmacia & Upjohn Company |
Chemotherapeutic microemulsion compositions of paclitaxel with improved oral bioavailability
|
CA2435350A1
(en)
*
|
2001-02-02 |
2002-08-15 |
Pharmacia Corporation |
Method of using a cyclooxygenase-2 inhibitor and sex steroids as a combination therapy for the treatment and prevention of dismenorrhea
|
AU2002306868A1
(en)
*
|
2001-03-28 |
2002-10-15 |
Pharmacia Corporation |
Therapeutic combinations for cardiovascular and inflammatory indications
|
US7695736B2
(en)
*
|
2001-04-03 |
2010-04-13 |
Pfizer Inc. |
Reconstitutable parenteral composition
|
ITMI20010733A1
(it)
|
2001-04-05 |
2002-10-05 |
Recordati Chem Pharm |
Uso di inibitori dell'isoenzina cox-2 per il trattamento dell'incontinenza urinaria
|
US20030105144A1
(en)
|
2001-04-17 |
2003-06-05 |
Ping Gao |
Stabilized oral pharmaceutical composition
|
US6673818B2
(en)
|
2001-04-20 |
2004-01-06 |
Pharmacia Corporation |
Fluoro-substituted benzenesulfonyl compounds for the treatment of inflammation
|
WO2002094264A1
(en)
*
|
2001-05-23 |
2002-11-28 |
Tularik Inc. |
Ccr4 antagonists
|
US20030153801A1
(en)
*
|
2001-05-29 |
2003-08-14 |
Pharmacia Corporation |
Compositions of cyclooxygenase-2 selective inhibitors and radiation for inhibition or prevention of cardiovascular disease
|
CA2448627A1
(en)
*
|
2001-05-31 |
2002-12-05 |
Pharmacia Corporation |
Skin-permeable composition comprising a selective cyclooxygenase-2 inhibitor a monohydric alcohol
|
US20060167074A1
(en)
*
|
2001-06-19 |
2006-07-27 |
Norbert Muller |
Methods and compositions for the treatment of psychiatric disorders
|
DE10129320A1
(de)
*
|
2001-06-19 |
2003-04-10 |
Norbert Mueller |
Verwendung von COX-2 Inhibitoren zur Behandlung von Schizophrenie, wahnhaften Störungen, affektiven Störungen oder Ticstörungen
|
UA80682C2
(en)
*
|
2001-08-06 |
2007-10-25 |
Pharmacia Corp |
Orally deliverable stabilized oral suspension formulation and process for the incresaing physical stability of thixotropic pharmaceutical composition
|
US20040067992A1
(en)
*
|
2001-08-10 |
2004-04-08 |
Pharmacia Corporation |
Compositions of a cyclooxygenase-2 selective inhibitor and a carbonic anhydrase inhibitor for the treatment of neoplasia
|
WO2003013655A2
(en)
*
|
2001-08-10 |
2003-02-20 |
Pharmacia Corporation |
Carbonic anhydrase inhibitors
|
US20050101563A1
(en)
*
|
2001-08-14 |
2005-05-12 |
Pharmacia Corporation |
Method and compositions for the treatment and prevention of pain and inflammation
|
US20030114416A1
(en)
*
|
2001-08-14 |
2003-06-19 |
Pharmacia Corporation |
Method and compositions for the treatment and prevention of pain and inflammation with a cyclooxygenase-2 selective inhibitor and chondroitin sulfate
|
AR038957A1
(es)
|
2001-08-15 |
2005-02-02 |
Pharmacia Corp |
Terapia de combinacion para el tratamiento del cancer
|
WO2003022815A1
(en)
*
|
2001-09-10 |
2003-03-20 |
Sugen, Inc. |
3-(4,5,6,7-tetrahydroindol-2-ylmethylidiene)-2-indolinone derivatives as kinase inhibitors
|
US20030236308A1
(en)
*
|
2001-09-18 |
2003-12-25 |
Pharmacia Corporation |
Compositions of cyclooxygenase-2 selective inhibitors and acetaminophen for treatment and prevention of inflammation, inflammation-mediated disorders and pain
|
WO2003024958A2
(en)
*
|
2001-09-18 |
2003-03-27 |
Onconova Therapeutics, Inc. |
Processes for the preparation of 1,5-diaryl-3-substituted-pyrazoles
|
US20030114483A1
(en)
*
|
2001-09-18 |
2003-06-19 |
Pharmacia Corporation |
Compositions of chromene cyclooxygenase-2 selective inhibitors and acetaminophen for treatment and prevention of inflammation, inflammation-mediated disorders and pain
|
AU2002330042A1
(en)
|
2001-09-18 |
2003-04-01 |
Onconova Therapeutics, Inc. |
Process for the preparation of 1,5-diarylpyrazoles
|
EP1427706B1
(en)
*
|
2001-09-19 |
2007-05-30 |
Pharmacia Corporation |
Substituted pyrazolo compounds for the treatment of inflammation
|
US20030105334A1
(en)
*
|
2001-10-02 |
2003-06-05 |
Letendre Leo J. |
Method for preparing benzenesulfonyl compounds
|
AR037097A1
(es)
|
2001-10-05 |
2004-10-20 |
Novartis Ag |
Compuestos acilsulfonamidas, composiciones farmaceuticas y el uso de dichos compuestos para la preparacion de un medicamento
|
US6809204B2
(en)
*
|
2001-10-12 |
2004-10-26 |
Onconova Therapeutics, Inc. |
Processes for the preparation of substituted isoxazoles and 2-isoxazolines
|
US20030162824A1
(en)
*
|
2001-11-12 |
2003-08-28 |
Krul Elaine S. |
Methods of treating or preventing a cardiovascular condition using a cyclooxygenase-1 inhibitor
|
CA2466504A1
(en)
*
|
2001-11-13 |
2003-05-22 |
Pharmacia Corporation |
Oral dosage form of a sulfonamide prodrug
|
CA2468266A1
(en)
|
2001-12-06 |
2003-06-19 |
Merck & Co., Inc. |
Substituted bicyclic pyrimidinones as a mitotic kinesin ksp inhibitors
|
JP2005516927A
(ja)
*
|
2001-12-13 |
2005-06-09 |
アボット・ラボラトリーズ |
癌治療用のキナーゼ阻害剤としての3−(フェニル−アルコキシ)−5−(フェニル)−ピリジン誘導体および関連化合物
|
US20040126438A1
(en)
*
|
2001-12-13 |
2004-07-01 |
Obukowicz Mark G. |
Selective cox-2 inhibition from plant extracts
|
US20040062823A1
(en)
*
|
2001-12-13 |
2004-04-01 |
Obukowicz Mark G. |
Selective cox-2 inhibition from non-edible plant extracts
|
BR0306820A
(pt)
*
|
2002-01-10 |
2004-12-07 |
Pharmacia & Up John Company |
Uso de inibidores cox-2 em combinação com agentes antivirais para o tratamento de infecções de papilomavìrus
|
US20030212138A1
(en)
*
|
2002-01-14 |
2003-11-13 |
Pharmacia Corporation |
Combinations of peroxisome proliferator-activated receptor-alpha agonists and cyclooxygenase-2 selective inhibitors and therapeutic uses therefor
|
US20030220374A1
(en)
*
|
2002-01-14 |
2003-11-27 |
Pharmacia Corporation |
Compositions and methods of treatment involving peroxisome proliferator-activated receptor-gamma agonists and cyclooxygenase-2 selective inhibitors
|
TW200403072A
(en)
*
|
2002-01-23 |
2004-03-01 |
Upjohn Co |
Combination therapy for the treatment of bacterial infections
|
US20100311701A1
(en)
*
|
2002-02-15 |
2010-12-09 |
Transform Pharmaceuticals, Inc |
Pharmaceutical Co-Crystal Compositions
|
US7927613B2
(en)
*
|
2002-02-15 |
2011-04-19 |
University Of South Florida |
Pharmaceutical co-crystal compositions
|
US20050025791A1
(en)
*
|
2002-06-21 |
2005-02-03 |
Julius Remenar |
Pharmaceutical compositions with improved dissolution
|
US7790905B2
(en)
*
|
2002-02-15 |
2010-09-07 |
Mcneil-Ppc, Inc. |
Pharmaceutical propylene glycol solvate compositions
|
EP1915992A1
(en)
|
2002-02-19 |
2008-04-30 |
Pharmacia Corporation |
Use of cyclooxygenase inhibitors and antimuscarinic agents for the treatment of incontinence
|
JP4906233B2
(ja)
*
|
2002-03-01 |
2012-03-28 |
ユニバーシティー オブ サウス フロリダ |
少なくとも1種の有効薬剤成分を含有する多構成要素固相
|
US20030232871A1
(en)
*
|
2002-03-15 |
2003-12-18 |
Sheikh Ahmad Y. |
Crystalline parecoxib sodium
|
US8481772B2
(en)
|
2002-04-01 |
2013-07-09 |
University Of Southern California |
Trihydroxy polyunsaturated eicosanoid derivatives
|
US7902257B2
(en)
|
2002-04-01 |
2011-03-08 |
University Of Southern California |
Trihydroxy polyunsaturated eicosanoid
|
AU2003216920A1
(en)
|
2002-04-08 |
2003-10-20 |
Glaxo Group Limited |
(2-((2-alkoxy)-phenyl)-cyclopent-1-enyl) aromatic carbo and heterocyclic acid and derivatives
|
CA2482510A1
(en)
*
|
2002-04-18 |
2003-10-30 |
Pharmacia Corporation |
Monotherapy for the treatment of parkinson`s disease with cyclooxygenase-2 (cox 2) inhibitor(s)
|
US20040034083A1
(en)
*
|
2002-04-18 |
2004-02-19 |
Stephenson Diane T. |
Combination therapy for the treatment of Parkinson's disease with cyclooxygenase-2 (COX2) inhibitor(s)
|
US7273616B2
(en)
*
|
2002-05-10 |
2007-09-25 |
The Trustees Of Columbia University In The City Of New York |
Genetically engineered cell lines and systems for propagating Varicella zoster virus and methods of use thereof
|
JP2005535644A
(ja)
*
|
2002-06-26 |
2005-11-24 |
ファルマシア コーポレイション |
安定な非経口パレコキシブ液体製剤
|
WO2004002409A2
(en)
|
2002-06-27 |
2004-01-08 |
Nitromed, Inc. |
Cyclooxygenase-2 selective inhibitors, compositions and methods of use
|
EP1539679A4
(en)
|
2002-06-28 |
2007-07-04 |
Nitromed Inc |
OXIM- AND / OR HYDRAZO-CONTAINING, NITROSED AND / OR NITROSYLATED CYCLOOXIGENASE-2 SELECTIVE INHIBITORS, COMPOSITIONS AND USE METHODS
|
MXPA05000259A
(es)
*
|
2002-07-02 |
2005-04-11 |
Pharmacia Corp |
Uso de inhibidores selectivos de ciclooxigenasa-2 y agentes tromboliticos para el tratamiento o prevencion de un evento vaso-oclusivo.
|
US7759395B2
(en)
*
|
2002-08-12 |
2010-07-20 |
The Brigham And Women's Hospital, Inc. |
Use of docosatrienes, resolvins and their stable analogs in the treatment of airway diseases and asthma
|
EP1537067B1
(en)
*
|
2002-08-12 |
2009-11-18 |
Brigham And Women's Hospital |
Resolvins: biotemplates for therapeutic interventions
|
UY27939A1
(es)
|
2002-08-21 |
2004-03-31 |
Glaxo Group Ltd |
Compuestos
|
AU2003267231A1
(en)
*
|
2002-09-20 |
2004-04-08 |
Transform Pharmaceuticals, Inc. |
Pharmaceutical compositions with improved dissolution
|
KR100484525B1
(ko)
*
|
2002-10-15 |
2005-04-20 |
씨제이 주식회사 |
이소티아졸 유도체, 그 제조방법 및 약제학적 조성물
|
US20040082543A1
(en)
*
|
2002-10-29 |
2004-04-29 |
Pharmacia Corporation |
Compositions of cyclooxygenase-2 selective inhibitors and NMDA receptor antagonists for the treatment or prevention of neuropathic pain
|
GB0225548D0
(en)
|
2002-11-01 |
2002-12-11 |
Glaxo Group Ltd |
Compounds
|
US20040092566A1
(en)
*
|
2002-11-12 |
2004-05-13 |
Graneto Matthew J. |
Celecoxib prodrug
|
US20040147581A1
(en)
*
|
2002-11-18 |
2004-07-29 |
Pharmacia Corporation |
Method of using a Cox-2 inhibitor and a 5-HT1A receptor modulator as a combination therapy
|
US20040127531A1
(en)
*
|
2002-11-21 |
2004-07-01 |
Lu Guang Wei |
Adhesive coated sheet for dermal delivery of a selective cyclooxygenase-2 inhibitor
|
US20040126415A1
(en)
*
|
2002-11-21 |
2004-07-01 |
Lu Guang Wei |
Dermal delivery of a water-soluble selective cyclooxygenase-2 inhibitor
|
US20050020658A1
(en)
*
|
2002-11-21 |
2005-01-27 |
Katsuyuki Inoo |
Selective cyclooxygenase-2 inhibitor patch
|
CA2509605C
(en)
|
2002-12-13 |
2010-10-05 |
Warner-Lambert Company Llc |
Alpha-2-delta ligand to treat lower urinary tract symptoms
|
US20040235925A1
(en)
*
|
2002-12-17 |
2004-11-25 |
Pharmacia Corporation |
Method for the treatment, prevention, or inhibition of a CNS disorder and/or pain and inflammation using a combination of duloxetine, venlafaxine or atomoxetine and a cyclooxygenase-2 selective inhibitor and compositions thereof
|
US20040204411A1
(en)
*
|
2002-12-17 |
2004-10-14 |
Pharmacia Corporation |
Method for the treatment, prevention, or inhibition of a CNS disorder and/or pain and inflammation using a combination of reboxetine and a cyclooxygenase-2 selective inhibitor and compositions thereof
|
US20080153894A1
(en)
*
|
2002-12-19 |
2008-06-26 |
Pharmacia Corporation |
Cyclooxygenase-2 inhibitor and antibacterial agent combination for intramammary treatment of mastitis
|
BR0317539A
(pt)
*
|
2002-12-19 |
2005-11-22 |
Pharmacia Corp |
Métodos e composições para o tratamento de infecções por vìrus da herpes usando inibidores seletivos da ou ciclooxigenase-2 ou inibidores da ciclooxigenase-2 em combinação com agentes antivirais
|
AU2003300264A1
(en)
*
|
2002-12-20 |
2004-07-22 |
Pharmacia Corporation |
Compositions of cyclooxygenase-2 selective inhibitors and selective serotonin reuptake inhibitors for the treatment or prevention of a vaso-occlusive event
|
ES2215474B1
(es)
|
2002-12-24 |
2005-12-16 |
J. URIACH & CIA S.A. |
Nuevos derivados de fosforamida.
|
US7332183B2
(en)
|
2002-12-26 |
2008-02-19 |
Pozen Inc. |
Multilayer dosage forms containing NSAIDs and triptans
|
US8183290B2
(en)
|
2002-12-30 |
2012-05-22 |
Mcneil-Ppc, Inc. |
Pharmaceutically acceptable propylene glycol solvate of naproxen
|
WO2004060367A1
(en)
*
|
2002-12-30 |
2004-07-22 |
Fujisawa Pharmaceutical Co., Ltd. |
Imidazole and triazole derivatives useful as selective cox-1 inhibitors
|
US20050026902A1
(en)
*
|
2003-01-31 |
2005-02-03 |
Timothy Maziasz |
Methods and compositions for the treatment or prevention of human immunodeficiency virus and related conditions using cyclooxygenase-2 selective inhibitors and antiviral agents
|
US20040176378A1
(en)
*
|
2003-02-12 |
2004-09-09 |
Pharmacia Corporation |
Compositions of a cyclooxygenase-2 selective inhibitor and an amphetamine for the treatment of reduced blood flow to the central nervous system
|
WO2004078143A2
(en)
*
|
2003-03-05 |
2004-09-16 |
The Brigham And Women's Hospital Inc. |
Methods for identification and uses of anti-inflammatory receptors for eicosapentaenoic acid analogs
|
US20050004098A1
(en)
*
|
2003-03-20 |
2005-01-06 |
Britten Nancy Jean |
Dispersible formulation of an anti-inflammatory agent
|
DK1608407T3
(da)
*
|
2003-03-20 |
2006-12-04 |
Pharmacia Corp |
Dispergébar formulering af et antiinflammatorisk middel
|
US20040214753A1
(en)
*
|
2003-03-20 |
2004-10-28 |
Britten Nancy Jean |
Dispersible pharmaceutical composition for treatment of mastitis and otic disorders
|
US20050009931A1
(en)
*
|
2003-03-20 |
2005-01-13 |
Britten Nancy Jean |
Dispersible pharmaceutical composition for treatment of mastitis and otic disorders
|
US20040214861A1
(en)
*
|
2003-03-28 |
2004-10-28 |
Pharmacia Corporation |
Compositions of a cyclooxygenase-2 selective inhibitors and 5-HT1B1D antagonists for the treatment and prevention of migraine
|
US20040220155A1
(en)
*
|
2003-03-28 |
2004-11-04 |
Pharmacia Corporation |
Method of providing a steroid-sparing benefit with a cyclooxygenase-2 inhibitor and compositions therewith
|
US20050143431A1
(en)
*
|
2003-04-04 |
2005-06-30 |
Hetero Drugs Limited |
Novel crystalline forms of parecoxib sodium
|
AU2004231106A1
(en)
*
|
2003-04-14 |
2004-10-28 |
The Institutes For Pharmaceutical Discovery, Llc |
N- (((((1,3-thiazol-2-yl) amino) carbonyl) phenyl) sulfonyl) phenylalanine derivatives and related compounds for the treatment of diabetes
|
US20040229803A1
(en)
*
|
2003-04-22 |
2004-11-18 |
Pharmacia Corporation |
Compositions of a cyclooxygenase-2 selective inhibitor and a potassium ion channel modulator for the treatment of pain, inflammation or inflammation mediated disorders
|
WO2004093813A2
(en)
*
|
2003-04-22 |
2004-11-04 |
Pharmacia Corporation |
Compositions of a cyclooxygenase-2 selective inhibitor and a calcium modulating agent for the treatment of pain, inflammation or inflammation mediated disorders
|
US20050009733A1
(en)
*
|
2003-04-22 |
2005-01-13 |
Pharmacia Corporation |
Compositions of a cyclooxygenase-2 selective inhibitor and a potassium ion channel modulator for the treatment of central nervous system damage
|
WO2004093814A2
(en)
*
|
2003-04-22 |
2004-11-04 |
Pharmacia Corporation |
Compositions of a cyclooxygenase-2 selective inhibitor and a sodium channel blocker
|
WO2004093816A2
(en)
*
|
2003-04-22 |
2004-11-04 |
Pharmacia Corporation |
Compositions comprising a selective cox-2 inhibitor and a calcium modulating agent
|
WO2004093811A2
(en)
*
|
2003-04-22 |
2004-11-04 |
Pharmacia Corporation |
Compositions of a cyclooxygenase-2 selective inhibitor and a sodium ion channel blocker for the treatment of central nervous system damage
|
CA2523714A1
(en)
|
2003-04-30 |
2004-11-18 |
The Institutes For Pharmaceutical Discovery, Llc |
Substituted carboxylic acids
|
US20040220167A1
(en)
*
|
2003-05-02 |
2004-11-04 |
Nasrollah Samiy |
Methods of treating neuralgic pain
|
EP1534305B9
(en)
|
2003-05-07 |
2007-03-07 |
Osteologix A/S |
Treating cartilage / bone conditions with water-soluble strontium salts
|
US20050107387A1
(en)
*
|
2003-05-13 |
2005-05-19 |
Pharmacia Corporation |
Compositions of a cyclooxygenase-2 selective inhibitor and a peroxisome proliferator activated receptor agonist for the treatment of ischemic mediated central nervous system disorders
|
BRPI0410305A
(pt)
*
|
2003-05-14 |
2006-05-23 |
Pharmacia Corp |
composições de um inibidor seletivo de ciclooxigenase-2 á base de benzenossulfonamida ou metilsulfonilbenzeno e um agente colinérgico para o tratamento de redução de fluxo sangüìneo ou traumatismo do sistema nervoso central
|
US20050026919A1
(en)
*
|
2003-05-14 |
2005-02-03 |
Pharmacia Corporation |
Compositions of a cyclooxygenase-2 selective inhibitor and a cholinergic agent for the treatment of reduced blood flow or trauma to the central nervous system
|
WO2004103283A2
(en)
*
|
2003-05-14 |
2004-12-02 |
Pharmacia Corporation |
Compositions of a cyclooxygenase-2 selective inhibitor and a central nervous system stimulant for the treatment of central nervous system damage
|
US20050113433A1
(en)
*
|
2003-05-14 |
2005-05-26 |
Pharmacia Corporation |
Compositions of a phenyl acetic acid cyclooxygenase-2 selective inhibitor and a cholinergic agent for the treatment of reduced blood flow or trauma to the central nervous system
|
US20050113376A1
(en)
*
|
2003-05-27 |
2005-05-26 |
Pharmacia Corporation |
Compositions of a cyclooxygenase-2 selective inhibitor, a xanthine compound and an alcohol for the treatment of ischemic mediated central nervous system disorders or injury
|
WO2004105699A2
(en)
*
|
2003-05-28 |
2004-12-09 |
Pharmacia Corporation |
Compositions of a cyclooxygenase-2 selective inhibitor and a cannabinoid agent for the treatment of central nervous system damage
|
CA2526730A1
(en)
|
2003-05-30 |
2004-12-09 |
Ranbaxy Laboratories Limited |
Substituted pyrrole derivatives
|
US20050054646A1
(en)
*
|
2003-06-09 |
2005-03-10 |
Pharmacia Corporation |
Compositions of a cyclooxygenase-2 selective inhibitor and an antioxidant agent for the treatment of central nervous system disorders
|
US20050065154A1
(en)
*
|
2003-06-24 |
2005-03-24 |
Pharmacia Corporation |
Treatment of migraine accompanied by nausea with a combination of cyclooxygenase-2 selective inhibitors and anti-nausea agents
|
US20050080083A1
(en)
*
|
2003-07-10 |
2005-04-14 |
Pharmacia Corporation |
Compositions of a cyclooxygenase-2 selective inhibitor and an angiotensin II receptor antagonist for the treatment of central nervous system damage
|
US20050101597A1
(en)
*
|
2003-07-10 |
2005-05-12 |
Pharmacia Corporation |
Compositions of a cyclooxygenase-2 selective inhibitior and a non-NMDA glutamate modulator for the treatment of central nervous system damage
|
WO2005016249A2
(en)
*
|
2003-07-11 |
2005-02-24 |
Pharmacia Corporation |
Compositions of a chromene or phenyl acetic acid cyclooxygenase-2 selective inhibitor and an ace inhibitor for the treatment of central nervous system damage
|
US20050080084A1
(en)
*
|
2003-07-11 |
2005-04-14 |
Pharmacia Corporation |
Compositions of a cyclooxygenase-2 selective inhibitor and a serotonin-modulating agent for the treatment of central nervous system damage
|
WO2005009342A2
(en)
*
|
2003-07-16 |
2005-02-03 |
Pharmacia Corporation |
Method for the treatment or prevention of dermatological disorders with a cyclooxygenase-2 inhibitor alone and in combination with a dermatological treatment agent and compositions therewith
|
US20050075341A1
(en)
*
|
2003-07-17 |
2005-04-07 |
Pharmacia Corporation |
Compositions of a cyclooxygenase-2 selective inhibitor and an IKK inhibitor for the treatment of ischemic mediated central nervous system disorders or injury
|
JPWO2005012268A1
(ja)
*
|
2003-07-30 |
2006-09-14 |
塩野義製薬株式会社 |
イソオキサゾール環を有するスルホンアミド誘導体
|
CA2536173A1
(en)
*
|
2003-08-20 |
2005-03-03 |
Nitromed, Inc. |
Nitrosated and nitrosylated cardiovascular compounds, compositions and methods of use
|
US20050119262A1
(en)
*
|
2003-08-21 |
2005-06-02 |
Pharmacia Corporation |
Method for preventing or treating an optic neuropathy with a cox-2 inhibitor and an intraocular pressure reducing agent
|
WO2005018569A2
(en)
*
|
2003-08-22 |
2005-03-03 |
Pharmacia Corporation |
Compositions of a cyclooxygenase-2 selective inhibitor and a serotonin modulating agent for the treatment of neoplasia
|
WO2005018564A2
(en)
*
|
2003-08-22 |
2005-03-03 |
Pharmacia Corporation |
Compositions of a cyclooxygenase-2 selective inhibitor and a low-molecular-weight heparin for the treatment of central nervous system damage
|
US20050107350A1
(en)
*
|
2003-08-22 |
2005-05-19 |
Pharmacia Corporation |
Method for the treatment or prevention of bone disorders with a cyclooxygenase-2 inhibitor alone and in combination with a bone disorder treatment agent and compositions therewith
|
WO2005018563A2
(en)
*
|
2003-08-22 |
2005-03-03 |
Pharmacia Corporation |
Compositions of a cyclooxygenase-2 selective inhibitor and a phosphodiesterase inhibitor for the treatment of ischemic mediated central nervous system disorders or injury
|
US20050085479A1
(en)
*
|
2003-08-27 |
2005-04-21 |
Pharmacia Corporation |
Mediated central nervous system compositions of a cyclooxygenase-2 selective inhibitor and a corticotropin releasing factor antagonist for the treatment of ischemic disorders or injury
|
AU2004270162B2
(en)
*
|
2003-08-28 |
2010-05-13 |
Nicox S.A. |
Nitrosated ad nitrosylated diuretic compouds, compositions and methods of use
|
US20050187278A1
(en)
*
|
2003-08-28 |
2005-08-25 |
Pharmacia Corporation |
Treatment or prevention of vascular disorders with Cox-2 inhibitors in combination with cyclic AMP-specific phosphodiesterase inhibitors
|
WO2005023189A2
(en)
*
|
2003-09-03 |
2005-03-17 |
Pharmacia Corporation |
Method of cox-2 selective inhibitor and nitric oxide-donating agent
|
EP1670417A2
(en)
*
|
2003-10-03 |
2006-06-21 |
Pharmacia Corporation |
Compositions of a cyclooxygenase-2 selective inhibitor administered under hypothermic conditions for the treatment of ischenic mediated central nervous system disorders or injury
|
BRPI0415939A
(pt)
*
|
2003-11-12 |
2007-01-02 |
Pharmacia & Upjohn Co Llc |
composições de um inibidor seletivo da ciclooxigenase-2 e um agente de modulação do fator neurotrófico para o tratamento de distúrbios mediados pelo sistema nervoso central
|
EP1708700A1
(en)
*
|
2003-12-24 |
2006-10-11 |
Pharmacia Corporation |
Metal salts of parecoxib as prodrugs of the cox-2 inhibitor valdecoxib for the treatment of inflammation, pain and/or fever
|
EP1708718A1
(en)
|
2004-01-22 |
2006-10-11 |
Pfizer Limited |
Triazole derivatives which inhibit vasopressin antagonistic activity
|
EP1755537A4
(en)
*
|
2004-04-14 |
2009-12-09 |
Univ Boston |
METHOD AND COMPOSITIONS FOR PREVENTING OR TREATING PERIODONTOPATHIA
|
JP2007534740A
(ja)
*
|
2004-04-28 |
2007-11-29 |
ファイザー・インク |
バソプレッシンV1a受容体の阻害剤としての3−ヘテロシクリル−4−フェニル−トリアゾール誘導体
|
DE602005023730D1
(de)
|
2004-07-01 |
2010-11-04 |
Merck Sharp & Dohme |
Inhibitoren von mitotischem kinesin
|
ES2257929B1
(es)
*
|
2004-07-16 |
2007-05-01 |
Laboratorios Del Dr. Esteve, S.A. |
Derivados de pirazolina, procedimiento para su obtencion y utilizacion de los mismos como agentes terapeuticos.
|
US20080260817A1
(en)
*
|
2004-07-22 |
2008-10-23 |
Phenil Jayantilal Patel |
Compositions for the Treatment of Inflammation and Pain Using a Combination of a Cox-2 Selective Inhibitor and a Ltb4 Receptor Antagonist
|
WO2006041855A2
(en)
|
2004-10-04 |
2006-04-20 |
Nitromed, Inc. |
Compositions and methods using apocynin compounds and nitric oxide donors
|
US20080300292A1
(en)
*
|
2004-11-08 |
2008-12-04 |
Nitromed, Inc |
Nitrosated and Nitrosylated Compounds, Compositions and Methods for the Treatment of Ophthalmic Disorders
|
WO2006066968A1
(en)
|
2004-12-23 |
2006-06-29 |
Glaxo Group Limited |
Pyridine compounds for the treatment of prostaglandin mediated diseases
|
EP1846380A4
(en)
*
|
2005-01-21 |
2010-02-17 |
Nicox Sa |
HETEROCYCLIC NITROGEN MONOXIDE DONOR COMPOSITIONS CONTAINING CARDIOVASCULAR COMPOUNDS, AND METHODS OF USING THE SAME
|
WO2007086884A2
(en)
*
|
2005-02-16 |
2007-08-02 |
Nitromed, Inc. |
Organic nitric oxide donor salts of antimicrobial compounds, compositions and methods of use
|
US7521435B2
(en)
*
|
2005-02-18 |
2009-04-21 |
Pharma Diagnostics, N.V. |
Silicon containing compounds having selective COX-2 inhibitory activity and methods of making and using the same
|
CA2597463A1
(en)
*
|
2005-02-28 |
2006-09-08 |
Nitromed, Inc. |
Cardiovascular compounds comprising nitric oxide enhancing groups, compositions and methods of use
|
KR101193797B1
(ko)
|
2005-04-26 |
2012-10-23 |
화이자 인코포레이티드 |
P-카드헤린 항체
|
AU2006244393B2
(en)
*
|
2005-05-05 |
2012-06-21 |
Cook Biotech Incorporated |
Implantable materials and methods for inhibiting tissue adhesion formation
|
ATE550019T1
(de)
|
2005-05-17 |
2012-04-15 |
Merck Sharp & Dohme |
Cis-4-ä(4-chlorophenyl)sulfonylü-4-(2,5- difluorophenyl)cyclohexanepropansäure zur behandlug von krebs
|
EP1885713A1
(en)
*
|
2005-05-18 |
2008-02-13 |
Pfizer Limited |
1, 2, 4 -triazole derivatives as vasopressin antagonists
|
WO2006127591A2
(en)
*
|
2005-05-23 |
2006-11-30 |
Nitromed, Inc. |
Organic nitric oxide enhancing salts of nonsteroidal antiinflammatory compounds, compositions and methods of use
|
HUP0500730A2
(en)
*
|
2005-07-29 |
2007-02-28 |
Richter Gedeon Vegyuszeti Gyar |
1,2-diaryl-heterocyclic compounds, their preparation, pharmaceutical compositions comprising thereof and their use
|
EP1915157A4
(en)
|
2005-08-02 |
2010-09-01 |
Nicox Sa |
NICKEL OXYGENIZING ANTIMICROBIAL COMPOUNDS, COMPOSITIONS AND USE PROCESSES
|
PE20070335A1
(es)
*
|
2005-08-30 |
2007-04-21 |
Novartis Ag |
Benzimidazoles sustituidos y metodos para su preparacion
|
CA2621371C
(en)
*
|
2005-09-07 |
2018-05-15 |
Amgen Fremont Inc. |
Human monoclonal antibodies to activin receptor-like kinase-1
|
US8273792B2
(en)
*
|
2005-10-03 |
2012-09-25 |
The Brigham And Women's Hospital, Inc. |
Anti-inflammatory actions of neuroprotectin D1/protectin D1 and it's natural stereoisomers
|
EP1942909A4
(en)
*
|
2005-10-04 |
2010-01-06 |
Nitromed Inc |
METHODS OF TREATING RESPIRATORY DISORDERS
|
SG166829A1
(en)
|
2005-11-08 |
2010-12-29 |
Ranbaxy Lab Ltd |
Process for (3r, 5r)-7-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4- [(4-hydroxy methyl phenyl amino) carbonyl]-pyrrol-1-yl]-3, 5-dihydroxy-heptanoic acid hemi calcium salt
|
EP1954685A4
(en)
*
|
2005-11-16 |
2009-11-11 |
Nitromed Inc |
FUROXANE COMPOUNDS, COMPOSITIONS AND METHODS OF USE
|
US8636986B2
(en)
*
|
2005-11-18 |
2014-01-28 |
The Forsyth Institute |
Treatment and prevention of bone loss using resolvins
|
US20090053328A1
(en)
*
|
2005-12-20 |
2009-02-26 |
Nitromed, Inc. |
Nitric Oxide Enhancing Glutamic Acid Compounds, Compositions and Methods of Use
|
NL2000351C2
(nl)
|
2005-12-22 |
2007-09-11 |
Pfizer Prod Inc |
Estrogeen-modulatoren.
|
US20080293702A1
(en)
*
|
2005-12-22 |
2008-11-27 |
Nitromed, Inc. |
Nitric Oxide Enhancing Pyruvate Compounds, Compositions and Methods of Use
|
EP1978964A4
(en)
|
2006-01-24 |
2009-12-09 |
Merck & Co Inc |
JAK2 tyrosine kinase Inhibition
|
GB0603041D0
(en)
|
2006-02-15 |
2006-03-29 |
Angeletti P Ist Richerche Bio |
Therapeutic compounds
|
EP2007705A4
(en)
*
|
2006-03-29 |
2011-09-07 |
Nicox Sa |
NITROGEN MONOXIDE REINFORCING PROSTAGLANDIN COMPOUNDS, COMPOSITION AND APPLICATION PROCESS
|
LT2010528T
(lt)
|
2006-04-19 |
2017-12-27 |
Novartis Ag |
6-o-pakeistieji benzoksazolo junginiai bei csf-1r signalo perdavimo slopinimo būdai
|
EP2027087A2
(en)
|
2006-05-18 |
2009-02-25 |
MannKind Corporation |
Intracellular kinase inhibitors
|
WO2008033931A1
(en)
*
|
2006-09-13 |
2008-03-20 |
The Institutes For Pharmaceutical Discovery, Llc |
Para-xylylene carboxylic acids and isothiazolones useful as protein tyrosine phosphatases (ptps) in particular ptp-ib
|
CA2664113C
(en)
|
2006-09-22 |
2013-05-28 |
Merck & Co., Inc. |
Use of platencin and platensimycin as fatty acid synthesis inhibitors to treat obesity, diabetes and cancer
|
US20110218176A1
(en)
|
2006-11-01 |
2011-09-08 |
Barbara Brooke Jennings-Spring |
Compounds, methods, and treatments for abnormal signaling pathways for prenatal and postnatal development
|
EA017171B1
(ru)
|
2006-12-22 |
2012-10-30 |
Рекордати Айерленд Лимитед |
КОМБИНИРОВАННАЯ ТЕРАПИЯ ЗАБОЛЕВАНИЙ НИЖНИХ МОЧЕВЫВОДЯЩИХ ПУТЕЙ С ИСПОЛЬЗОВАНИЕМ ЛИГАНДОВ αδ И НЕСТЕРОИДНЫХ ПРОТИВОВОСПАЛИТЕЛЬНЫХ ПРЕПАРАТОВ (НПВП)
|
JP4611444B2
(ja)
|
2007-01-10 |
2011-01-12 |
イステイチユート・デイ・リチエルケ・デイ・ビオロジア・モレコラーレ・ピ・アンジエレツテイ・エツセ・ピー・アー |
ポリ(adp−リボース)ポリメラーゼ(parp)阻害剤としてのアミド置換インダゾール
|
KR100843351B1
(ko)
*
|
2007-01-30 |
2008-07-03 |
한국과학기술연구원 |
중추신경계 질환 치료제로 유효한n-벤질-n-(2-디메틸아미노-에틸)-벤젠술폰아미드 화합물
|
CN101679266B
(zh)
|
2007-03-01 |
2015-05-06 |
诺华股份有限公司 |
Pim激酶抑制剂及其应用方法
|
GB0704407D0
(en)
|
2007-03-07 |
2007-04-18 |
Glaxo Group Ltd |
Compounds
|
AU2008254425A1
(en)
|
2007-05-21 |
2008-11-27 |
Novartis Ag |
CSF-1R inhibitors, compositions, and methods of use
|
EP3103791B1
(en)
|
2007-06-27 |
2018-01-31 |
Merck Sharp & Dohme Corp. |
4-carboxybenzylamino derivatives as histone deacetylase inhibitors
|
BRPI0814542A2
(pt)
|
2007-07-12 |
2014-09-30 |
Tragara Pharmaceuticals Inc |
Métodos e composições para o tratamento de câncer, tumores e desordens relacionadas a tumores
|
US7943658B2
(en)
|
2007-07-23 |
2011-05-17 |
Bristol-Myers Squibb Company |
Indole indane amide compounds useful as CB2 agonists and method
|
CA2699157A1
(en)
|
2007-09-10 |
2009-03-19 |
Calcimedica, Inc. |
Compounds that modulate intracellular calcium
|
US8598184B2
(en)
|
2008-03-03 |
2013-12-03 |
Tiger Pharmatech |
Protein kinase inhibitors
|
GB0813142D0
(en)
|
2008-07-17 |
2008-08-27 |
Glaxo Group Ltd |
Novel compounds
|
GB0813144D0
(en)
|
2008-07-17 |
2008-08-27 |
Glaxo Group Ltd |
Novel compounds
|
TWI392673B
(zh)
|
2008-08-27 |
2013-04-11 |
Calcimedica Inc |
調控細胞內鈣離子濃度之化合物
|
EP2177215A1
(en)
|
2008-10-17 |
2010-04-21 |
Laboratorios Del. Dr. Esteve, S.A. |
Co-crystals of tramadol and NSAIDs
|
GB0903493D0
(en)
|
2009-02-27 |
2009-04-08 |
Vantia Ltd |
New compounds
|
JP5212177B2
(ja)
*
|
2009-02-27 |
2013-06-19 |
東レ株式会社 |
γ−ケトアセタール化合物及びピロール誘導体の製造方法
|
KR101069175B1
(ko)
|
2009-04-19 |
2011-09-30 |
중앙대학교 산학협력단 |
신규 아미노설포닐아릴이소옥사졸계 화합물 및 이를 포함하는 다약제내성 억제용 약제학적 조성물
|
WO2011012622A1
(en)
|
2009-07-30 |
2011-02-03 |
Glaxo Group Limited |
Benzoxazinone derivatives for the treatment of glytl mediated disorders
|
WO2011023753A1
(en)
|
2009-08-27 |
2011-03-03 |
Glaxo Group Limited |
Benzoxazine derivatives as glycine transport inhibitors
|
JP5099731B1
(ja)
|
2009-10-14 |
2012-12-19 |
メルク・シャープ・アンド・ドーム・コーポレーション |
p53活性を増大する置換ピペリジン及びその使用
|
GB201000685D0
(en)
|
2010-01-15 |
2010-03-03 |
Glaxo Group Ltd |
Novel compounds
|
CN101805290A
(zh)
*
|
2010-04-01 |
2010-08-18 |
中国人民解放军第四军医大学 |
氨基磺酰吡唑类化合物及其用途
|
EP2563759B1
(en)
|
2010-04-27 |
2022-04-06 |
Calcimedica, Inc. |
Compounds that modulate intracellular calcium
|
HUE029570T2
(en)
|
2010-04-27 |
2017-03-28 |
Calcimedica Inc |
Intracellular calcium modifying compounds
|
GB201007789D0
(en)
|
2010-05-10 |
2010-06-23 |
Glaxo Group Ltd |
Novel Compound
|
GB201007791D0
(en)
|
2010-05-10 |
2010-06-23 |
Glaxo Group Ltd |
Novel compounds
|
JP2013528172A
(ja)
|
2010-05-21 |
2013-07-08 |
ファイザー・インク |
2−フェニルベンゾイルアミド
|
EP2584903B1
(en)
|
2010-06-24 |
2018-10-24 |
Merck Sharp & Dohme Corp. |
Novel heterocyclic compounds as erk inhibitors
|
JP5815029B2
(ja)
|
2010-07-09 |
2015-11-17 |
クオンベルゲンセ プハルマセウトイカルス リミテッド |
カルシウムチャネル遮断薬としてのテトラゾール化合物
|
US8518907B2
(en)
|
2010-08-02 |
2013-08-27 |
Merck Sharp & Dohme Corp. |
RNA interference mediated inhibition of catenin (cadherin-associated protein), beta 1 (CTNNB1) gene expression using short interfering nucleic acid (siNA)
|
DK2606134T3
(da)
|
2010-08-17 |
2019-07-22 |
Sirna Therapeutics Inc |
RNA-Interferens-formidlet inhibering af hepatitis-B-virus (HBV)-genekspression ved hjælp af kort interfererende nukleinsyre (siNA)
|
US8653118B2
(en)
*
|
2010-08-20 |
2014-02-18 |
Allergan, Inc. |
Compounds act at multiple prostaglandin receptors giving a general anti-inflammatory response
|
EP2608669B1
(en)
|
2010-08-23 |
2016-06-22 |
Merck Sharp & Dohme Corp. |
NOVEL PYRAZOLO[1,5-a]PYRIMIDINE DERIVATIVES AS mTOR INHIBITORS
|
MX337711B
(es)
|
2010-08-27 |
2016-03-15 |
Calcimedica Inc |
Compuestos que modulan el calcio intracelular.
|
WO2012030685A2
(en)
|
2010-09-01 |
2012-03-08 |
Schering Corporation |
Indazole derivatives useful as erk inhibitors
|
US9242981B2
(en)
|
2010-09-16 |
2016-01-26 |
Merck Sharp & Dohme Corp. |
Fused pyrazole derivatives as novel ERK inhibitors
|
DK2632472T3
(en)
|
2010-10-29 |
2018-03-19 |
Sirna Therapeutics Inc |
RNA INTERFERENCE-MEDIATED INHIBITION OF GENE EXPRESSION USING SHORT INTERFERRING NUCLEIC ACIDS (SINA)
|
EP2654748B1
(en)
|
2010-12-21 |
2016-07-27 |
Merck Sharp & Dohme Corp. |
Indazole derivatives useful as erk inhibitors
|
JP6058556B2
(ja)
|
2011-01-19 |
2017-01-11 |
クオンベルゲンセ プハルマセウトイカルス リミテッド |
CaV2.2カルシウムチャンネルブロッカーとしてのピペラジン誘導体
|
WO2012120414A2
(en)
|
2011-03-04 |
2012-09-13 |
Pfizer Inc. |
Edn3-like peptides and uses thereof
|
US20140045847A1
(en)
|
2011-04-21 |
2014-02-13 |
Piramal Enterprises Limited |
Crystalline form of a salt of a morpholino sulfonyl indole derivative and a process for its preparation
|
WO2013063214A1
(en)
|
2011-10-27 |
2013-05-02 |
Merck Sharp & Dohme Corp. |
Novel compounds that are erk inhibitors
|
WO2013066729A1
(en)
|
2011-10-31 |
2013-05-10 |
Merck Sharp & Dohme Corp. |
Aminopyrimidinones as interleukin receptor-associated kinase inhibitors
|
WO2013074988A1
(en)
*
|
2011-11-17 |
2013-05-23 |
The Regents Of The University Of Colorado, A Body Corporate |
Methods and compositions for enhanced drug delivery to the eye and extended delivery formulations
|
GB201122113D0
(en)
|
2011-12-22 |
2012-02-01 |
Convergence Pharmaceuticals |
Novel compounds
|
EP3358013B1
(en)
|
2012-05-02 |
2020-06-24 |
Sirna Therapeutics, Inc. |
Short interfering nucleic acid (sina) compositions
|
RU2660429C2
(ru)
|
2012-09-28 |
2018-07-06 |
Мерк Шарп И Доум Корп. |
Новые соединения, которые являются ингибиторами erk
|
US9512116B2
(en)
|
2012-10-12 |
2016-12-06 |
Calcimedica, Inc. |
Compounds that modulate intracellular calcium
|
AU2013352568B2
(en)
|
2012-11-28 |
2019-09-19 |
Merck Sharp & Dohme Llc |
Compositions and methods for treating cancer
|
ES2707305T3
(es)
|
2012-12-20 |
2019-04-03 |
Merck Sharp & Dohme |
Imidazopiridinas sustituidas como inhibidores de HDM2
|
WO2014120748A1
(en)
|
2013-01-30 |
2014-08-07 |
Merck Sharp & Dohme Corp. |
2,6,7,8 substituted purines as hdm2 inhibitors
|
EP2967049B1
(en)
*
|
2013-03-15 |
2020-09-02 |
University Of Southern California |
Methods, compounds, and compositions for the treatment of angiotensin-related diseases
|
US20160166576A1
(en)
|
2013-07-11 |
2016-06-16 |
Merck Sharp & Dohme Corp. |
Substituted amidopyrazole inhibitors of interleukin receptor-associated kinases (irak-4)
|
WO2015034925A1
(en)
|
2013-09-03 |
2015-03-12 |
Moderna Therapeutics, Inc. |
Circular polynucleotides
|
CN104418818B
(zh)
*
|
2013-09-04 |
2017-01-11 |
天津汉瑞药业有限公司 |
帕瑞昔布钠无水化合物
|
WO2015054283A1
(en)
|
2013-10-08 |
2015-04-16 |
Calcimedica, Inc. |
Compounds that modulate intracellular calcium
|
CN105085425B
(zh)
*
|
2014-05-23 |
2018-01-30 |
昆药集团股份有限公司 |
一种制备帕瑞昔布的方法
|
JO3589B1
(ar)
|
2014-08-06 |
2020-07-05 |
Novartis Ag |
مثبطات كيناز البروتين c وطرق استخداماتها
|
GB201417497D0
(en)
|
2014-10-03 |
2014-11-19 |
Convergence Pharmaceuticals |
Novel use
|
GB201417500D0
(en)
|
2014-10-03 |
2014-11-19 |
Convergence Pharmaceuticals |
Novel use
|
GB201417499D0
(en)
|
2014-10-03 |
2014-11-19 |
Convergence Pharmaceuticals |
Novel use
|
CN104557754A
(zh)
*
|
2015-01-04 |
2015-04-29 |
成都克莱蒙医药科技有限公司 |
一种帕瑞昔布钠杂质的合成方法
|
US10155765B2
(en)
|
2015-03-12 |
2018-12-18 |
Merck Sharp & Dohme Corp. |
Carboxamide inhibitors of IRAK4 activity
|
WO2016144846A1
(en)
|
2015-03-12 |
2016-09-15 |
Merck Sharp & Dohme Corp. |
Pyrazolopyrimidine inhibitors of irak4 activity
|
EP3268003B1
(en)
|
2015-03-12 |
2020-07-29 |
Merck Sharp & Dohme Corp. |
Thienopyrazine inhibitors of irak4 activity
|
WO2017023774A1
(en)
*
|
2015-07-31 |
2017-02-09 |
The Johns Hopkins University |
Prodrugs of glutamine analogs
|
US9598361B1
(en)
*
|
2016-04-12 |
2017-03-21 |
King Saud University |
Amino substituted acetamide derivative
|
EP3706742B1
(en)
|
2017-11-08 |
2023-03-15 |
Merck Sharp & Dohme LLC |
Prmt5 inhibitors
|
CN108299331A
(zh)
*
|
2018-03-02 |
2018-07-20 |
成都新恒创药业有限公司 |
一种帕瑞昔布钠光降解杂质及其制备、检测方法和应用
|
CN108164521B
(zh)
*
|
2018-03-02 |
2020-11-13 |
成都新恒创药业有限公司 |
一种帕瑞昔布钠降解杂质及其制备、检测方法和应用
|
WO2020033282A1
(en)
|
2018-08-07 |
2020-02-13 |
Merck Sharp & Dohme Corp. |
Prmt5 inhibitors
|
EP3833667B1
(en)
|
2018-08-07 |
2024-03-13 |
Merck Sharp & Dohme LLC |
Prmt5 inhibitors
|
CN110305071A
(zh)
*
|
2019-07-23 |
2019-10-08 |
成都通德药业有限公司 |
一种帕瑞昔布钠中间体帕瑞昔布的合成方法
|
EP4077282A4
(en)
|
2019-12-17 |
2023-11-08 |
Merck Sharp & Dohme LLC |
PRMT5 INHIBITORS
|
CA3209491A1
(en)
|
2021-03-15 |
2022-09-22 |
Saul Yedgar |
Hyaluronic acid-conjugated dipalmitoyl phosphatidyl ethanolamine in combination with non-steroidal anti-inflammatory drugs (nsaids) for treating or alleviating inflammatory disease
|
CN115784991A
(zh)
*
|
2022-11-22 |
2023-03-14 |
合肥医工医药股份有限公司 |
N-(苯磺酰基)酰胺衍生物及其制备方法和用途
|