US6830923B1
(en)
*
|
1989-03-16 |
2004-12-14 |
Boehringer Inglheim International Gmbh |
Genetics units for inhibiting the function of RNA
|
US5354844A
(en)
*
|
1989-03-16 |
1994-10-11 |
Boehringer Ingelheim International Gmbh |
Protein-polycation conjugates
|
AU625013B2
(en)
*
|
1989-11-03 |
1992-06-25 |
Vanderbilt University |
Method of in vivo delivery of functioning foreign genes
|
US5804604A
(en)
*
|
1989-12-21 |
1998-09-08 |
Biogen, Inc. |
Tat-derived transport polypeptides and fusion proteins
|
US5670617A
(en)
*
|
1989-12-21 |
1997-09-23 |
Biogen Inc |
Nucleic acid conjugates of tat-derived transport polypeptides
|
US6316003B1
(en)
|
1989-12-21 |
2001-11-13 |
Whitehead Institute For Biomedical Research |
Tat-derived transport polypeptides
|
ES2091916T3
(es)
*
|
1989-12-21 |
1996-11-16 |
Whitehead Biomedical Inst |
Metodo para suministrar moleculas en el interior de celulas eucarioticas.
|
DE59107006D1
(de)
*
|
1990-04-25 |
1996-01-18 |
Hoechst Ag |
Pharmakologische Zubereitung, enthaltend Polyelektrolytkomplexe in mikropartikulärer Form und mindestens einen Wirkstoff.
|
DE4110410C2
(de)
*
|
1991-03-29 |
1999-05-27 |
Boehringer Ingelheim Int |
Neue Protein-Polykation-Konjugate
|
ATE126442T1
(de)
*
|
1990-05-18 |
1995-09-15 |
Boehringer Ingelheim Int |
Neue protein-polykation-konjugate.
|
DE4104186A1
(de)
*
|
1991-02-12 |
1992-08-13 |
Genentech Inc |
Neue, ueber endozytose in hoehere eukaryotische zellen aufnehmbare, nukleinsaeure enthaltende komplexe
|
DE4110409C2
(de)
*
|
1991-03-29 |
1999-05-27 |
Boehringer Ingelheim Int |
Neue Protein-Polykation-Konjugate
|
DE4115038A1
(de)
*
|
1991-05-08 |
1992-11-12 |
Genentech Inc |
Neue konjugate, bestehend aus einem glykoprotein und einer nukleinsaeure-bindenden substanz
|
US6030954A
(en)
*
|
1991-09-05 |
2000-02-29 |
University Of Connecticut |
Targeted delivery of poly- or oligonucleotides to cells
|
RU2138553C1
(ru)
*
|
1991-09-30 |
1999-09-27 |
Берингер Ингельгейм Интернациональ ГмбХ |
Трансфекционная композиция для высших эукариотных клеток, комплекс нуклеиновой кислоты, пригодный в качестве компонента трансфекционной композиции, конъюгат, пригодный в качестве компонента трансфекционной композиции, эндосомолитический пептид, пригодный в качестве компонента трансфекционной композиции
|
US5981273A
(en)
*
|
1991-09-30 |
1999-11-09 |
Boehringer Ingelheim Int'l. Gmbh |
Composition comprising an endosomolytic agent for introducing nucleic acid complexes into higher eucaryotic cells
|
US5521291A
(en)
*
|
1991-09-30 |
1996-05-28 |
Boehringer Ingelheim International, Gmbh |
Conjugates for introducing nucleic acid into higher eucaryotic cells
|
IL103059A0
(en)
*
|
1991-09-30 |
1993-02-21 |
Boehringer Ingelheim Int |
Conjugates for introducing nucleic acid into higher eucaryotic cells
|
NZ244306A
(en)
*
|
1991-09-30 |
1995-07-26 |
Boehringer Ingelheim Int |
Composition for introducing nucleic acid complexes into eucaryotic cells, complex containing nucleic acid and endosomolytic agent, peptide with endosomolytic domain and nucleic acid binding domain and preparation
|
DE4139001A1
(de)
*
|
1991-11-27 |
1993-06-03 |
Boehringer Mannheim Gmbh |
Verfahren zur einschleusung von nukleinsaeuren in zellen
|
WO1993013205A1
(de)
*
|
1991-12-23 |
1993-07-08 |
Boehringer Ingelheim International Gmbh |
Neuroblastom-assoziiertes regulator-gen
|
US5922859A
(en)
*
|
1992-02-01 |
1999-07-13 |
Boehringer Ingelheim International Gmbh |
Complexes containing nucleic acid which can be taken-up by endocytosis into higher eukaryotic cells
|
CA2133323C
(en)
*
|
1992-04-03 |
2010-10-26 |
Francis C. Szoka, Jr. |
Self-assembling polynucleotide delivery system
|
US5656609A
(en)
*
|
1992-09-24 |
1997-08-12 |
University Of Connecticut |
Method of enhancing and/or prolonging expression of gene introduced into a cell using colchicine
|
DE4311651A1
(de)
*
|
1993-04-08 |
1994-10-13 |
Boehringer Ingelheim Int |
Virus für den Transport von Fremd-DNA in höhere eukaryotische Zellen
|
EP0693939A1
(de)
*
|
1993-04-14 |
1996-01-31 |
Roche Diagnostics GmbH |
Nukleinsäure-transferpeptide und deren verwendung zur einschleusung von nukleinsäuren in eukaryontische zellen
|
US6106824A
(en)
*
|
1993-08-13 |
2000-08-22 |
The Rockefeller University |
Expression of growth associated protein B-50/GAP-43 in vitro and in vivo
|
RU2025487C1
(ru)
*
|
1993-10-18 |
1994-12-30 |
Товарищество с ограниченной ответственностью "БиоПрогресс" |
Способ направленной генетической трансформации молочной железы животного и устройство для введения генетического материала в молочный проток молочной железы животного
|
US20030036056A1
(en)
*
|
1994-01-24 |
2003-02-20 |
John J. Rossi |
Inhibitors and target molecule co-localization
|
FR2715847B1
(fr)
*
|
1994-02-08 |
1996-04-12 |
Rhone Poulenc Rorer Sa |
Composition contenant des acides nucléiques, préparation et utilisations.
|
JPH10501681A
(ja)
*
|
1994-02-22 |
1998-02-17 |
ダナ−ファーバー キャンサー インスティチュート |
核酸送達システムならびにその合成および使用方法
|
US6037329A
(en)
|
1994-03-15 |
2000-03-14 |
Selective Genetics, Inc. |
Compositions containing nucleic acids and ligands for therapeutic treatment
|
US6551618B2
(en)
|
1994-03-15 |
2003-04-22 |
University Of Birmingham |
Compositions and methods for delivery of agents for neuronal regeneration and survival
|
US5844107A
(en)
*
|
1994-03-23 |
1998-12-01 |
Case Western Reserve University |
Compacted nucleic acids and their delivery to cells
|
WO1995025809A1
(en)
*
|
1994-03-23 |
1995-09-28 |
Ohio University |
Compacted nucleic acids and their delivery to cells
|
US6077835A
(en)
*
|
1994-03-23 |
2000-06-20 |
Case Western Reserve University |
Delivery of compacted nucleic acid to cells
|
US5972901A
(en)
|
1994-03-23 |
1999-10-26 |
Case Western Reserve University |
Serpin enzyme complex receptor--mediated gene transfer
|
US5670347A
(en)
*
|
1994-05-11 |
1997-09-23 |
Amba Biosciences Llc |
Peptide-mediated gene transfer
|
US6284880B1
(en)
|
1994-05-30 |
2001-09-04 |
Boehringer Ingelheim International Gmbh |
Chicken embryo lethal orphan (CELO) virus GAM-1
|
DE4418965A1
(de)
*
|
1994-05-31 |
1995-12-07 |
Boehringer Ingelheim Int |
Verfahren zum Einbringen von Nukleinsäure in höhere eukaryotische Zellen
|
JPH11505505A
(ja)
*
|
1994-06-27 |
1999-05-21 |
ザ・ジョンズ・ホプキンス・ユニバーシティー |
ターゲッティングされた遺伝子輸送システム
|
US5728399A
(en)
*
|
1994-06-29 |
1998-03-17 |
University Of Conn. |
Use of a bacterial component to enhance targeted delivery of polynucleotides to cells
|
US6048837A
(en)
*
|
1994-08-17 |
2000-04-11 |
The Rockefeller University |
OB polypeptides as modulators of body weight
|
US6124439A
(en)
*
|
1994-08-17 |
2000-09-26 |
The Rockefeller University |
OB polypeptide antibodies and method of making
|
US6124448A
(en)
*
|
1994-08-17 |
2000-09-26 |
The Rockfeller University |
Nucleic acid primers and probes for the mammalian OB gene
|
US6471956B1
(en)
|
1994-08-17 |
2002-10-29 |
The Rockefeller University |
Ob polypeptides, modified forms and compositions thereto
|
US6001968A
(en)
|
1994-08-17 |
1999-12-14 |
The Rockefeller University |
OB polypeptides, modified forms and compositions
|
US6309853B1
(en)
|
1994-08-17 |
2001-10-30 |
The Rockfeller University |
Modulators of body weight, corresponding nucleic acids and proteins, and diagnostic and therapeutic uses thereof
|
US6350730B1
(en)
|
1994-08-17 |
2002-02-26 |
The Rockefeller University |
OB polypeptides and modified forms as modulators of body weight
|
US6962686B2
(en)
|
1994-10-12 |
2005-11-08 |
California Institute Of Technology |
Cell-specific gene delivery vehicles
|
US6232295B1
(en)
|
1994-10-12 |
2001-05-15 |
Jon Faiz Kayyem |
Cell-specific contrast agent and gene delivery vehicles
|
GB9422495D0
(en)
*
|
1994-11-08 |
1995-01-04 |
Medical Res Council |
DNA transfer method
|
US6221959B1
(en)
|
1994-11-18 |
2001-04-24 |
Supratek Pharma, Inc. |
Polynucleotide compositions
|
WO1996021036A2
(en)
*
|
1994-12-30 |
1996-07-11 |
Chiron Viagene, Inc. |
Nucleic acid condensing agents with reduced immunogenicity
|
US5795587A
(en)
|
1995-01-23 |
1998-08-18 |
University Of Pittsburgh |
Stable lipid-comprising drug delivery complexes and methods for their production
|
JPH11511112A
(ja)
|
1995-02-10 |
1999-09-28 |
ユニバーシティ・オブ・マサチューセッツ |
外因性化合物の送達
|
FR2730637B1
(fr)
*
|
1995-02-17 |
1997-03-28 |
Rhone Poulenc Rorer Sa |
Composition pharmaceutique contenant des acides nucleiques, et ses utilisations
|
US6420549B1
(en)
|
1995-06-06 |
2002-07-16 |
Isis Pharmaceuticals, Inc. |
Oligonucleotide analogs having modified dimers
|
US5646034A
(en)
*
|
1995-06-07 |
1997-07-08 |
Mamounas; Michael |
Increasing rAAV titer
|
US20030069173A1
(en)
*
|
1998-03-16 |
2003-04-10 |
Life Technologies, Inc. |
Peptide-enhanced transfections
|
JP4338106B2
(ja)
*
|
1995-06-07 |
2009-10-07 |
ライフ テクノロジーズ コーポレーション |
ペプチド増強カチオン脂質トランスフェクション
|
US6051429A
(en)
|
1995-06-07 |
2000-04-18 |
Life Technologies, Inc. |
Peptide-enhanced cationic lipid transfections
|
US6127116A
(en)
|
1995-08-29 |
2000-10-03 |
Washington University |
Functional DNA clone for hepatitis C virus (HCV) and uses thereof
|
US5744326A
(en)
*
|
1996-03-11 |
1998-04-28 |
The Immune Response Corporation |
Use of viral CIS-acting post-transcriptional regulatory sequences to increase expression of intronless genes containing near-consensus splice sites
|
CA2248538A1
(en)
*
|
1996-03-14 |
1997-09-18 |
The Immune Response Corporation |
Targeted delivery of genes encoding interferon
|
US5898031A
(en)
|
1996-06-06 |
1999-04-27 |
Isis Pharmaceuticals, Inc. |
Oligoribonucleotides for cleaving RNA
|
US9096636B2
(en)
|
1996-06-06 |
2015-08-04 |
Isis Pharmaceuticals, Inc. |
Chimeric oligomeric compounds and their use in gene modulation
|
US7812149B2
(en)
|
1996-06-06 |
2010-10-12 |
Isis Pharmaceuticals, Inc. |
2′-Fluoro substituted oligomeric compounds and compositions for use in gene modulations
|
US5679559A
(en)
*
|
1996-07-03 |
1997-10-21 |
University Of Utah Research Foundation |
Cationic polymer and lipoprotein-containing system for gene delivery
|
CN1181422A
(zh)
*
|
1996-10-31 |
1998-05-13 |
上海市肿瘤研究所 |
与生长因子受体结合的多肽所构建的基因转移载体
|
US6387700B1
(en)
|
1996-11-04 |
2002-05-14 |
The Reagents Of The University Of Michigan |
Cationic peptides, Cys-Trp-(LYS)n, for gene delivery
|
US5965441A
(en)
*
|
1996-11-13 |
1999-10-12 |
The General Hospital Coporation |
HSV/AAV hybrid amplicon vectors
|
FR2755976B1
(fr)
|
1996-11-15 |
1999-01-15 |
Idm Immuno Designed Molecules |
Nouveaux complexes d'acides nucleiques et de polymere substitue par des residus entrainant la destabilisation des membranes cellulaires
|
US7008776B1
(en)
|
1996-12-06 |
2006-03-07 |
Aventis Pharmaceuticals Inc. |
Compositions and methods for effecting the levels of high density lipoprotein (HDL) cholesterol and apolipoprotein AI very low density lipoprotein (VLDL) cholesterol and low density lipoprotein (LDL) cholesterol
|
US6153596A
(en)
*
|
1996-12-18 |
2000-11-28 |
Emory University |
Polycationic oligomers
|
US5969102A
(en)
|
1997-03-03 |
1999-10-19 |
St. Jude Children's Research Hospital |
Lymphocyte surface receptor that binds CAML, nucleic acids encoding the same and methods of use thereof
|
US7338759B1
(en)
|
1997-03-04 |
2008-03-04 |
Washington University |
HCV variants
|
US7049428B1
(en)
|
1998-03-04 |
2006-05-23 |
Washington University |
HCV variants
|
HUP0002922A3
(en)
|
1997-04-28 |
2003-03-28 |
Aventis Pharma Sa |
Adenovirus-mediated intratumoral delivery of an angiogenesis antagonist for the treatment of tumors
|
GB2341390B
(en)
*
|
1997-05-21 |
2000-11-08 |
Univ Leland Stanford Junior |
Composition and method for enhancing transport across biological membranes
|
US6958148B1
(en)
*
|
1998-01-20 |
2005-10-25 |
Pericor Science, Inc. |
Linkage of agents to body tissue using microparticles and transglutaminase
|
US6919076B1
(en)
|
1998-01-20 |
2005-07-19 |
Pericor Science, Inc. |
Conjugates of agents and transglutaminase substrate linking molecules
|
EP1054694A2
(en)
*
|
1998-02-13 |
2000-11-29 |
Selective Genetics, Inc. |
Concurrent flow mixing methods and apparatuses for the preparation of gene therapy vectors and compositions prepared thereby
|
US7101575B2
(en)
|
1998-03-19 |
2006-09-05 |
Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V. |
Production of nanocapsules and microcapsules by layer-wise polyelectrolyte self-assembly
|
EP1071472A4
(en)
*
|
1998-04-23 |
2002-04-17 |
Univ Michigan Technology Man W |
PEPTIDES FOR EFFICIENT GENE TRANSFER
|
US6169078B1
(en)
*
|
1998-05-12 |
2001-01-02 |
University Of Florida |
Materials and methods for the intracellular delivery of substances
|
US6171855B1
(en)
|
1998-05-28 |
2001-01-09 |
The Regents Of The University Of Michigan |
Vectors
|
US6927278B1
(en)
*
|
1998-09-01 |
2005-08-09 |
Trustees Of The University Of Pennsylvania |
Peptide scaffolds for transfer of molecules into eukaryotic cells
|
US6696089B2
(en)
|
1998-09-03 |
2004-02-24 |
Board Of Regents Of The University Of Nebraska |
Nanogel networks including polyion polymer fragments and biological agent compositions thereof
|
US6077709A
(en)
|
1998-09-29 |
2000-06-20 |
Isis Pharmaceuticals Inc. |
Antisense modulation of Survivin expression
|
ES2296419T3
(es)
|
1998-11-12 |
2008-04-16 |
Invitrogen Corporation |
Reactivos de transfeccion.
|
US6773911B1
(en)
|
1998-11-23 |
2004-08-10 |
Amgen Canada Inc. |
Apoptosis-inducing factor
|
US6395029B1
(en)
*
|
1999-01-19 |
2002-05-28 |
The Children's Hospital Of Philadelphia |
Sustained delivery of polyionic bioactive agents
|
US7098192B2
(en)
|
1999-04-08 |
2006-08-29 |
Isis Pharmaceuticals, Inc. |
Antisense oligonucleotide modulation of STAT3 expression
|
US6281005B1
(en)
|
1999-05-14 |
2001-08-28 |
Copernicus Therapeutics, Inc. |
Automated nucleic acid compaction device
|
US7049481B1
(en)
|
1999-05-21 |
2006-05-23 |
Board Of Control Of Michigan Technological University |
Cellulose synthase encoding polynucleotides and uses thereof
|
US7674951B1
(en)
|
1999-05-21 |
2010-03-09 |
Michigan Technological University |
Isolated cellulose synthase promoter regions
|
DE19929104A1
(de)
*
|
1999-06-24 |
2000-12-28 |
Aventis Pharma Gmbh |
Neue Vektorkomplexe und deren Verwendung für die Gentherapie
|
US6770740B1
(en)
|
1999-07-13 |
2004-08-03 |
The Regents Of The University Of Michigan |
Crosslinked DNA condensate compositions and gene delivery methods
|
DE19933506A1
(de)
*
|
1999-07-16 |
2001-01-25 |
Deutsches Krebsforsch |
Zelluläre Aufnahme von DNA
|
EP1209971A4
(en)
*
|
1999-08-20 |
2004-04-14 |
Mirus Corp |
POLYION COMPLEX LOAD INVERSION
|
US6593292B1
(en)
|
1999-08-24 |
2003-07-15 |
Cellgate, Inc. |
Compositions and methods for enhancing drug delivery across and into epithelial tissues
|
US6730293B1
(en)
|
1999-08-24 |
2004-05-04 |
Cellgate, Inc. |
Compositions and methods for treating inflammatory diseases of the skin
|
US6669951B2
(en)
|
1999-08-24 |
2003-12-30 |
Cellgate, Inc. |
Compositions and methods for enhancing drug delivery across and into epithelial tissues
|
US7229961B2
(en)
*
|
1999-08-24 |
2007-06-12 |
Cellgate, Inc. |
Compositions and methods for enhancing drug delivery across and into ocular tissues
|
US20010009759A1
(en)
*
|
1999-12-08 |
2001-07-26 |
Jsr Corporation |
Virus-binding particles, virus-separating reagent, separation of viruses, and detection of viruses
|
EP1242052A4
(en)
*
|
1999-12-29 |
2003-07-02 |
A James Mixson |
HISTIDIN COPOLYMER AND METHODS OF USE THEREOF
|
US7070807B2
(en)
*
|
1999-12-29 |
2006-07-04 |
Mixson A James |
Branched histidine copolymers and methods for using same
|
US20020055479A1
(en)
|
2000-01-18 |
2002-05-09 |
Cowsert Lex M. |
Antisense modulation of PTP1B expression
|
US6261840B1
(en)
|
2000-01-18 |
2001-07-17 |
Isis Pharmaceuticals, Inc. |
Antisense modulation of PTP1B expression
|
US20030134420A1
(en)
*
|
2000-02-18 |
2003-07-17 |
Lollo Charles Peter |
Methods and compositions for gene delivery
|
CA2402530C
(en)
|
2000-03-13 |
2014-01-14 |
Cornell Research Foundation, Inc. |
Blocking leukocyte emigration and inflammation by interfering with cd99
|
GB0018307D0
(en)
|
2000-07-26 |
2000-09-13 |
Aventis Pharm Prod Inc |
Polypeptides
|
AU5345901A
(en)
|
2000-04-13 |
2001-10-30 |
Univ Rockefeller |
Enhancement of antibody-mediated immune responses
|
US20020136732A1
(en)
*
|
2000-04-23 |
2002-09-26 |
Houston L. L. |
Compositions comprising carriers and transportable complexes
|
MXPA02011163A
(es)
|
2000-05-10 |
2004-08-19 |
Mayo Foundation |
Anticuerpos igm humanos con la capacidad de inducir remielinacion, y usos diagnosticos y terapeuticos de los mismos particularmente en el sistema nervioso central.
|
US6680172B1
(en)
|
2000-05-16 |
2004-01-20 |
Regents Of The University Of Michigan |
Treatments and markers for cancers of the central nervous system
|
US7355019B2
(en)
|
2000-06-06 |
2008-04-08 |
Sibtech, Inc. |
Cysteine-containing peptide tag for site-specific conjugation of proteins
|
ES2286133T3
(es)
|
2000-08-08 |
2007-12-01 |
St. Jude Children's Research Hospital |
Acidos nucleicos de polipeptidos de estreptococos del grupo b y composiciones terapeuticas y vacunas de los mismos.
|
US6846809B2
(en)
*
|
2000-09-25 |
2005-01-25 |
Board Of Regents, The University Of Texas System |
PEI: DNA vector formulations for in vitro and in vivo gene delivery
|
US20030166160A1
(en)
*
|
2001-09-06 |
2003-09-04 |
Hawley Stephen B. |
Compounds and molecular complexes comprising multiple binding regions directed to transcytotic ligands
|
WO2002028408A2
(en)
*
|
2000-10-02 |
2002-04-11 |
Arizeke Pharmaceuticals, Inc. |
Compositions and methods for the transport of biologically active agents across cellular barriers
|
US8105825B2
(en)
|
2000-10-03 |
2012-01-31 |
Intrexon Corporation |
Multiple inducible gene regulation system
|
DE10049010A1
(de)
*
|
2000-10-04 |
2002-04-18 |
Boehringer Ingelheim Int |
Transferrin-Polykation/DNS-Komplexe für die systemische Therapie von Tumorerkrankungen mit zytotoxischen Proteinen
|
CN100422210C
(zh)
|
2000-12-28 |
2008-10-01 |
Wyeth公司 |
来自肺炎链球菌的重组防护蛋白质
|
CA2445796C
(en)
|
2001-02-20 |
2014-09-16 |
Rheogene, Inc. |
Novel substitution mutant receptors and their use in a nuclear receptor-based inducible gene expression system
|
DK1572862T3
(da)
|
2001-02-20 |
2012-11-26 |
Intrexon Corp |
Kimære, retinoide x-receptorer og deres anvendelse i et hidtil ukendt ecdysonrecepttorbaseret inducerbart genekspressionssystem
|
EP1499349B1
(en)
|
2001-03-02 |
2009-11-18 |
The Rockefeller University |
Recombinant hybrid allergen constructs with reduced allergenicity that retain immunogenicity of the natural allergen
|
JP2004528309A
(ja)
*
|
2001-03-23 |
2004-09-16 |
ナプロ バイオセラピューティクス,インコーポレイテッド |
癌治療用分子複合体
|
US20030096748A1
(en)
*
|
2001-06-04 |
2003-05-22 |
The Regents Of The University Of Michigan |
Methods and compositions for the treatment of diseases associated with signal transduction aberrations
|
MXPA03011985A
(es)
|
2001-06-20 |
2004-03-26 |
Genentech Inc |
Composiciones y metodos para el diagnostico y tratamiento de tumores.
|
US7803915B2
(en)
|
2001-06-20 |
2010-09-28 |
Genentech, Inc. |
Antibody compositions for the diagnosis and treatment of tumor
|
CA2451643C
(en)
|
2001-06-21 |
2012-11-13 |
Isis Pharmaceuticals, Inc. |
Antisense modulation of superoxide dismutase 1, soluble expression
|
US7425545B2
(en)
|
2001-07-25 |
2008-09-16 |
Isis Pharmaceuticals, Inc. |
Modulation of C-reactive protein expression
|
US6964950B2
(en)
|
2001-07-25 |
2005-11-15 |
Isis Pharmaceuticals, Inc. |
Antisense modulation of C-reactive protein expression
|
US20030096772A1
(en)
|
2001-07-30 |
2003-05-22 |
Crooke Rosanne M. |
Antisense modulation of acyl CoA cholesterol acyltransferase-2 expression
|
US7407943B2
(en)
|
2001-08-01 |
2008-08-05 |
Isis Pharmaceuticals, Inc. |
Antisense modulation of apolipoprotein B expression
|
US7227014B2
(en)
|
2001-08-07 |
2007-06-05 |
Isis Pharmaceuticals, Inc. |
Antisense modulation of apolipoprotein (a) expression
|
KR101008758B1
(ko)
|
2001-09-18 |
2011-01-14 |
제넨테크, 인크. |
종양의 진단 및 치료를 위한 방법 및 이를 위한 조성물
|
AU2002334895B2
(en)
|
2001-10-09 |
2006-10-19 |
Isis Pharmaceuticals, Inc. |
Antisense modulation of insulin-like growth factor binding protein 5 expression
|
US6750019B2
(en)
|
2001-10-09 |
2004-06-15 |
Isis Pharmaceuticals, Inc. |
Antisense modulation of insulin-like growth factor binding protein 5 expression
|
MX339524B
(es)
|
2001-10-11 |
2016-05-30 |
Wyeth Corp |
Composiciones inmunogenicas novedosas para la prevencion y tratamiento de enfermedad meningococica.
|
CA2465860A1
(en)
|
2001-11-02 |
2004-04-22 |
Insert Therapeutics, Inc. |
Methods and compositions for therapeutic use of rna interference
|
US6965025B2
(en)
|
2001-12-10 |
2005-11-15 |
Isis Pharmaceuticals, Inc. |
Antisense modulation of connective tissue growth factor expression
|
EP2067472A1
(en)
|
2002-01-02 |
2009-06-10 |
Genentech, Inc. |
Compositions and methods for the diagnosis and treatment of tumor
|
US20030186916A1
(en)
*
|
2002-03-12 |
2003-10-02 |
Lei Yu |
Vector for transfection of eukaryotic cells
|
US20030180712A1
(en)
|
2002-03-20 |
2003-09-25 |
Biostratum Ab |
Inhibition of the beta3 subunit of L-type Ca2+ channels
|
WO2003086272A2
(en)
*
|
2002-04-16 |
2003-10-23 |
Kamada Ltd. |
Ultrapure transferrin for pharmaceutical compositions
|
NZ535925A
(en)
|
2002-04-16 |
2008-06-30 |
Genentech Inc |
An isolated antibody that binds to a particular polypeptide
|
US7199107B2
(en)
|
2002-05-23 |
2007-04-03 |
Isis Pharmaceuticals, Inc. |
Antisense modulation of kinesin-like 1 expression
|
US7074893B2
(en)
*
|
2002-06-03 |
2006-07-11 |
Regents Of The University Of Michigan |
Methods and compositions for the treatment of diseases associated with signal transduction aberrations
|
GB0215534D0
(en)
*
|
2002-07-04 |
2002-08-14 |
Ecole Polytech |
Selective photochemotherapy using oligonucleotide targeting agents
|
US7375093B2
(en)
|
2002-07-05 |
2008-05-20 |
Intrexon Corporation |
Ketone ligands for modulating the expression of exogenous genes via an ecdysone receptor complex
|
US7785608B2
(en)
|
2002-08-30 |
2010-08-31 |
Wyeth Holdings Corporation |
Immunogenic compositions for the prevention and treatment of meningococcal disease
|
CN1694959B
(zh)
|
2002-09-13 |
2013-09-18 |
雷普利瑟公司 |
非序列互补的抗病毒寡核苷酸
|
WO2004031350A2
(en)
|
2002-09-26 |
2004-04-15 |
Amgen, Inc. |
Modulation of forkhead box o1a expression
|
EP1560839A4
(en)
|
2002-11-05 |
2008-04-23 |
Isis Pharmaceuticals Inc |
CHIMERIC OLIGOMER COMPOUNDS AND THEIR USE IN GENE MODULATION
|
EP1578765A4
(en)
|
2002-11-05 |
2008-04-23 |
Isis Pharmaceuticals Inc |
OLIGOMERIC COMPOUNDS CONTAINING SUGAR SUBSTITUTE AND COMPOSITIONS FOR USE IN GENE MODULATION
|
SI2336318T1
(sl)
|
2002-11-13 |
2013-07-31 |
Genzyme Corporation |
Protismiselna modulacija ekspresije apolipoproteina B
|
AU2003294281B2
(en)
|
2002-11-13 |
2010-05-20 |
Kastle Therapeutics, Llc |
Antisense modulation of apolipoprotein B expression
|
US7144999B2
(en)
|
2002-11-23 |
2006-12-05 |
Isis Pharmaceuticals, Inc. |
Modulation of hypoxia-inducible factor 1 alpha expression
|
US7465708B2
(en)
|
2002-11-25 |
2008-12-16 |
Mixson A James |
Branched cationic copolymers and methods for antimicrobial use
|
US7304161B2
(en)
|
2003-02-10 |
2007-12-04 |
Intrexon Corporation |
Diaclhydrazine ligands for modulating the expression of exogenous genes in mammalian systems via an ecdysone receptor complex
|
US7468356B2
(en)
|
2003-02-11 |
2008-12-23 |
Antisense Therapeutics Ltd. |
Modulation of insulin like growth factor I receptor expression
|
US7803781B2
(en)
|
2003-02-28 |
2010-09-28 |
Isis Pharmaceuticals, Inc. |
Modulation of growth hormone receptor expression and insulin-like growth factor expression
|
US7456315B2
(en)
|
2003-02-28 |
2008-11-25 |
Intrexon Corporation |
Bioavailable diacylhydrazine ligands for modulating the expression of exogenous genes via an ecdysone receptor complex
|
US20040185559A1
(en)
|
2003-03-21 |
2004-09-23 |
Isis Pharmaceuticals Inc. |
Modulation of diacylglycerol acyltransferase 1 expression
|
US7598227B2
(en)
|
2003-04-16 |
2009-10-06 |
Isis Pharmaceuticals Inc. |
Modulation of apolipoprotein C-III expression
|
EP1620112A4
(en)
*
|
2003-04-17 |
2007-04-25 |
Univ Columbia |
DESMOGLEIN 4 IS A NEW GENUS INVOLVED IN HAIR GROWTH
|
US7399853B2
(en)
|
2003-04-28 |
2008-07-15 |
Isis Pharmaceuticals |
Modulation of glucagon receptor expression
|
BRPI0410886A
(pt)
|
2003-06-03 |
2006-07-04 |
Isis Pharmaceuticals Inc |
composto de filamento duplo, composição farmacêutica, sal farmaceuticamente aceitável, métodos de modificação do ácido nucleico que codifica a survivina humana, de inibição da expressão da suvivina em células ou tecidos, e de tratamento de uma condição associada com a expressão ou superexpressão da suvivina, e, oligonucleotìdeo de rnai de filamento único
|
EP1649061B1
(en)
|
2003-07-03 |
2010-08-25 |
University Of Medicine And Dentistry Of New Jersey |
Genes as diagnostic tools for autism
|
EP1648914A4
(en)
|
2003-07-31 |
2009-12-16 |
Regulus Therapeutics Inc |
OLIGOMERIC COMPOUNDS AND COMPOSITIONS USEFUL FOR MODULATING SMALL NON-CODING RNA
|
US7825235B2
(en)
|
2003-08-18 |
2010-11-02 |
Isis Pharmaceuticals, Inc. |
Modulation of diacylglycerol acyltransferase 2 expression
|
AU2004274942B2
(en)
|
2003-09-18 |
2008-02-28 |
Isis Pharmaceuticals, Inc. |
Modulation of eIF4E expression
|
CN1882602B
(zh)
|
2003-10-10 |
2011-02-09 |
阿尔卡米亚肿瘤股份有限公司 |
在疾病治疗中乙酰透明质酸合成的调节和降解
|
CA2543257C
(en)
|
2003-10-24 |
2013-12-31 |
Gencia Corporation |
Methods and compositions for delivering polynucleotides
|
US8062891B2
(en)
|
2003-10-24 |
2011-11-22 |
Gencia Corporation |
Nonviral vectors for delivering polynucleotides to plants
|
US8133733B2
(en)
|
2003-10-24 |
2012-03-13 |
Gencia Corporation |
Nonviral vectors for delivering polynucleotides to target tissues
|
US8507277B2
(en)
|
2003-10-24 |
2013-08-13 |
Gencia Corporation |
Nonviral vectors for delivering polynucleotides
|
US20090123468A1
(en)
|
2003-10-24 |
2009-05-14 |
Gencia Corporation |
Transducible polypeptides for modifying metabolism
|
US20050191653A1
(en)
|
2003-11-03 |
2005-09-01 |
Freier Susan M. |
Modulation of SGLT2 expression
|
EP2161283B1
(en)
|
2003-11-17 |
2014-06-04 |
Genentech, Inc. |
Compositions comprising antibodies against CD79b conjugated to a growth inhibitory agent or cytotoxic agent and methods for the treatment of tumor of hematopoietic origin
|
WO2005071080A2
(en)
|
2004-01-20 |
2005-08-04 |
Isis Pharmaceuticals, Inc. |
Modulation of glucocorticoid receptor expression
|
US7468431B2
(en)
|
2004-01-22 |
2008-12-23 |
Isis Pharmaceuticals, Inc. |
Modulation of eIF4E-BP2 expression
|
US8569474B2
(en)
|
2004-03-09 |
2013-10-29 |
Isis Pharmaceuticals, Inc. |
Double stranded constructs comprising one or more short strands hybridized to a longer strand
|
WO2005089268A2
(en)
|
2004-03-15 |
2005-09-29 |
Isis Pharmaceuticals, Inc. |
Compositions and methods for optimizing cleavage of rna by rnase h
|
DE102004013637A1
(de)
|
2004-03-19 |
2005-10-13 |
Capsulution Nanoscience Ag |
Verfahren zur Herstellung von CS-Partikeln und Mikrokapseln unter Verwendung poröser Template sowie CS-Partikel und Mikrokapseln
|
EP1730280B1
(en)
*
|
2004-03-26 |
2018-10-24 |
Curis, Inc. |
Rna interference modulators of hedgehog signaling and uses thereof
|
US20050244869A1
(en)
|
2004-04-05 |
2005-11-03 |
Brown-Driver Vickie L |
Modulation of transthyretin expression
|
EP2270513A3
(en)
|
2004-04-20 |
2011-04-06 |
Galapagos N.V. |
Methods, compositions and compound assays for inhibiting amyloid-beta protein production
|
EP1747462A2
(en)
|
2004-04-27 |
2007-01-31 |
Galapagos N.V. |
Methods, agents, and compound screening assays for inducing differentiation of undifferentiated mammalian cells into osteoblasts
|
US7935510B2
(en)
|
2004-04-30 |
2011-05-03 |
Intrexon Corporation |
Mutant receptors and their use in a nuclear receptor-based inducible gene expression system
|
US8394947B2
(en)
|
2004-06-03 |
2013-03-12 |
Isis Pharmaceuticals, Inc. |
Positionally modified siRNA constructs
|
US20090048192A1
(en)
*
|
2004-06-03 |
2009-02-19 |
Isis Pharmaceuticals, Inc. |
Double Strand Compositions Comprising Differentially Modified Strands for Use in Gene Modulation
|
EP2270160A1
(en)
|
2004-06-14 |
2011-01-05 |
Galapagos N.V. |
Methods for identification, and compounds useful for the treatment of degenerative and inflammatory diseases
|
TW200613554A
(en)
|
2004-06-17 |
2006-05-01 |
Wyeth Corp |
Plasmid having three complete transcriptional units and immunogenic compositions for inducing an immune response to HIV
|
US20070004658A1
(en)
|
2004-06-21 |
2007-01-04 |
Nick Vandeghinste |
Method and means for treatment of osteoarthritis
|
US7884086B2
(en)
|
2004-09-08 |
2011-02-08 |
Isis Pharmaceuticals, Inc. |
Conjugates for use in hepatocyte free uptake assays
|
EP1799825B1
(en)
*
|
2004-10-05 |
2011-06-29 |
The California Institute of Technology |
Aptamer regulated nucleic acids and uses thereof
|
US7485468B2
(en)
|
2004-10-15 |
2009-02-03 |
Galapagos Bv |
Molecular targets and compounds, and methods to identify the same, useful in the treatment of joint degenerative and inflammatory diseases
|
US8673268B2
(en)
|
2004-10-15 |
2014-03-18 |
Galapagos N.V. |
Molecular targets and compounds, and methods to identify the same, useful in the treatment of joint degenerative and inflammatory diseases
|
US9034650B2
(en)
|
2005-02-02 |
2015-05-19 |
Intrexon Corporation |
Site-specific serine recombinases and methods of their use
|
AU2006213686A1
(en)
|
2005-02-09 |
2006-08-17 |
Avi Bio Pharma, Inc. |
Antisense composition and method for treating muscle atrophy
|
BRPI0607985A2
(pt)
|
2005-03-10 |
2009-10-27 |
Genentech Inc |
modulador da dscr1, métodos de tratamento, método de melhoria de efeitos colaterais e método de inibição do crescimento de tumores
|
EP2360249A1
(en)
|
2005-03-31 |
2011-08-24 |
Calando Pharmaceuticals, Inc. |
Inhibitors of ribonucleotide reductase subunit 2 and uses thereof
|
US8088382B2
(en)
|
2005-07-05 |
2012-01-03 |
Cornell Research Foundation, Inc. |
Methods of inhibiting transendothelial migration of neutrophils and monocytes with anti-CD99L2 antibodies
|
WO2007019245A2
(en)
|
2005-08-03 |
2007-02-15 |
Board Of Control Of Michigan Technological University |
Methods for enhancing expression of secondary cell wall cellulose synthases in plants
|
EP1966377A2
(en)
|
2005-11-21 |
2008-09-10 |
Isis Pharmaceuticals, Inc. |
Modulation of eif4e-bp2 expression
|
WO2007089611A2
(en)
|
2006-01-26 |
2007-08-09 |
Isis Pharmaceuticals Inc. |
Compositions and their uses directed to huntingtin
|
CA2647277A1
(en)
|
2006-04-05 |
2007-11-08 |
Genentech, Inc. |
Method for using boc/cdo to modulate hedgehog signaling
|
EP2013344B1
(en)
|
2006-05-03 |
2012-08-29 |
Baltic Technology Development, Ltd. |
Antisense agents combining strongly bound base - modified oligonucleotide and artificial nuclease
|
US8198253B2
(en)
|
2006-07-19 |
2012-06-12 |
Isis Pharmaceuticals, Inc. |
Compositions and their uses directed to HBXIP
|
MX2009000976A
(es)
|
2006-07-28 |
2009-03-09 |
Sanofi Aventis |
Composicion y metodo para el tratamiento de tumores.
|
WO2008058291A2
(en)
|
2006-11-09 |
2008-05-15 |
California Institute Of Technology |
Modular aptamer-regulated ribozymes
|
WO2008073856A2
(en)
*
|
2006-12-08 |
2008-06-19 |
Massachusetts Institute Of Technology |
Delivery of nanoparticles and/or agents to cells
|
AR064642A1
(es)
|
2006-12-22 |
2009-04-15 |
Wyeth Corp |
Polinucleotido vector que lo comprende celula recombinante que comprende el vector polipeptido , anticuerpo , composicion que comprende el polinucleotido , vector , celula recombinante polipeptido o anticuerpo , uso de la composicion y metodo para preparar la composicion misma y preparar una composi
|
US8048998B2
(en)
*
|
2007-01-19 |
2011-11-01 |
Exiqon A/S |
Mediated cellular delivery of LNA oligonucleotides
|
EP2114981B1
(en)
|
2007-01-29 |
2013-05-08 |
Isis Pharmaceuticals, Inc. |
Compounds and methods for modulating protein expression
|
ES2379413T3
(es)
|
2007-02-22 |
2012-04-25 |
Genentech, Inc. |
Procedimientos para detectar la enfermedad inflamatoria del intestino
|
KR101583592B1
(ko)
*
|
2007-04-05 |
2016-01-12 |
심바이오텍 게젤샤프트 주어 포르슝 운트 엔트빅클룽 아우프 뎀 게비엣 데어 바이오테크놀로지 엠베하 |
비스-met 히스톤
|
MX2009012834A
(es)
|
2007-05-29 |
2010-05-17 |
Intrexon Corp |
Ligandos quirales de diacilhidrazina para modular la expresion de genes exogenos por medio de un complejo receptor de ecdisona.
|
EP2162747B1
(en)
|
2007-06-20 |
2014-04-30 |
Galapagos N.V. |
Molecular targets and methods to identify compounds for treating bone and joint degenerative diseases
|
WO2009011855A2
(en)
*
|
2007-07-16 |
2009-01-22 |
California Institute Of Technology |
Selection of nucleic acid-based sensor domains within nucleic acid switch platform
|
EP2185730A4
(en)
|
2007-08-23 |
2010-10-27 |
Intrexon Corp |
METHOD AND COMPOSITIONS FOR SICKNESS DIAGNOSIS
|
US8367815B2
(en)
*
|
2007-08-28 |
2013-02-05 |
California Institute Of Technology |
Modular polynucleotides for ligand-controlled regulatory systems
|
US20120165387A1
(en)
|
2007-08-28 |
2012-06-28 |
Smolke Christina D |
General composition framework for ligand-controlled RNA regulatory systems
|
US8865667B2
(en)
*
|
2007-09-12 |
2014-10-21 |
California Institute Of Technology |
Higher-order cellular information processing devices
|
KR20100068435A
(ko)
*
|
2007-09-17 |
2010-06-23 |
롬 앤드 하아스 컴패니 |
식물의 생리적 반응을 변형시키기 위한 조성물 및 방법
|
WO2009042971A2
(en)
|
2007-09-26 |
2009-04-02 |
Intrexon Corporation |
Synthetic 5'utrs, expression vectors, and methods for increasing transgene expression
|
NZ584848A
(en)
|
2007-09-28 |
2012-09-28 |
Intrexon Corp |
Therapeutic gene-switch constructs and bioreactors for the expression of biotherapeutic molecules, and uses thereof
|
MX2010003465A
(es)
|
2007-10-02 |
2010-07-05 |
Amgen Inc |
Incremento de eritropoyetina utilizando acidos nucleicos que hibridan para micro-arn y precursores de los mismos.
|
US7973019B1
(en)
|
2007-10-03 |
2011-07-05 |
Alcon Research, Ltd. |
Transferrin/transferrin receptor-mediated siRNA delivery
|
US20090123441A1
(en)
|
2007-10-08 |
2009-05-14 |
Intrexon Corporation |
Engineered Dendritic Cells and Uses for the Treatment of Cancer
|
WO2009065618A2
(de)
|
2007-11-22 |
2009-05-28 |
Biontex Laboratories Gmbh |
Verbesserung von transfektionsergebnissen nicht-viraler genliefersysteme durch beeinflussung des angeborenen immunsystems
|
DE102008023913A1
(de)
|
2008-05-16 |
2009-11-19 |
Biontex Laboratories Gmbh |
Verbesserung von Transfektionsergebnissen nicht-viraler Genliefersysteme durch Beeinflussung des angeborenen Immunsystems
|
DE102008016275A1
(de)
|
2008-03-28 |
2009-11-19 |
Biontex Laboratories Gmbh |
Verbesserung von Transfektionsergebnissen nicht-viraler Genliefersysteme durch Blockierung des angeborenen Immunsystems
|
DE102007056488A1
(de)
|
2007-11-22 |
2009-07-23 |
Biontex Laboratories Gmbh |
Steigerung von Transfektionseffizienzen nicht-viraler Genliefersysteme durch Blockierung des angeborenen Immunsystems
|
US9029524B2
(en)
*
|
2007-12-10 |
2015-05-12 |
California Institute Of Technology |
Signal activated RNA interference
|
EP2283133A2
(en)
|
2008-04-04 |
2011-02-16 |
Calando Pharmaceuticals, Inc. |
Compositions and use of epas1 inhibitors
|
US8093043B2
(en)
|
2008-06-04 |
2012-01-10 |
New York University |
β-TrCP1, β-TrCP2 and RSK1 or RSK2 inhibitors and methods for sensitizing target cells to apoptosis
|
US8815818B2
(en)
|
2008-07-18 |
2014-08-26 |
Rxi Pharmaceuticals Corporation |
Phagocytic cell delivery of RNAI
|
NZ601660A
(en)
|
2008-08-25 |
2014-05-30 |
Excaliard Pharmaceuticals Inc |
Antisense oligonucleotides directed against connective tissue growth factor and uses thereof
|
CA2736425A1
(en)
|
2008-09-11 |
2010-03-18 |
Galapagos Nv |
Method for identifying compounds useful for increasing the functional activity and cell surface expression of cf-associated mutant cystic fibrosis transmembrane conductance regulator
|
CN108165548B
(zh)
|
2008-09-22 |
2022-10-14 |
菲奥医药公司 |
减小大小的自递送RNAi化合物
|
KR20110081282A
(ko)
|
2008-11-05 |
2011-07-13 |
와이어쓰 엘엘씨 |
베타―용혈성 연쇄구균 (bhs) 질환의 예방을 위한 다성분 면역원성 조성물
|
RU2618688C2
(ru)
|
2008-12-04 |
2017-05-10 |
КьюРНА,Инк.,US |
Лечение связанных с геном-супрессором опухолей заболеваний посредством ингибирования природного транскрипта в антисмысловой ориентации относительно этого гена
|
JP6091752B2
(ja)
|
2008-12-04 |
2017-03-08 |
クルナ・インコーポレーテッド |
Epoに対する天然アンチセンス転写物の抑制によるエリスロポエチン(epo)関連疾患の治療
|
EP2370580B1
(en)
|
2008-12-04 |
2019-09-11 |
CuRNA, Inc. |
Treatment of sirtuin 1 (sirt1) related diseases by inhibition of natural antisense transcript to sirtuin 1
|
WO2010078536A1
(en)
|
2009-01-05 |
2010-07-08 |
Rxi Pharmaceuticals Corporation |
Inhibition of pcsk9 through rnai
|
WO2010090762A1
(en)
|
2009-02-04 |
2010-08-12 |
Rxi Pharmaceuticals Corporation |
Rna duplexes with single stranded phosphorothioate nucleotide regions for additional functionality
|
EP2216341A1
(en)
|
2009-02-10 |
2010-08-11 |
Novozymes Biopharma UK Limited |
Transferrin variants and conjugates
|
US20110319476A1
(en)
|
2009-02-12 |
2011-12-29 |
Opko Curna, Llc |
Treatment of glial cell derived neurotrophic factor (gdnf) related diseases by inhibition of natural antisense transcript to gdnf
|
HUE026280T2
(hu)
|
2009-02-12 |
2016-06-28 |
Curna Inc |
Agyi eredetû neutrotróf faktorral (brain-derived neurotrophic factor, BDNF) összefüggõ betegségek kezelése a BDNF-fel kapcsolatos természetes antiszensz transzkriptumok gátlása révén
|
US8329882B2
(en)
|
2009-02-18 |
2012-12-11 |
California Institute Of Technology |
Genetic control of mammalian cells with synthetic RNA regulatory systems
|
JP2012518181A
(ja)
|
2009-02-19 |
2012-08-09 |
ガラパゴス・ナムローゼ・フェンノートシャップ |
炎症を包含する疾患の診断及び治療に有用な同定方法及び化合物
|
EP2398481A2
(en)
|
2009-02-19 |
2011-12-28 |
Galapagos N.V. |
Methods for identifying and compounds useful for the diagnosis and treatment of diseases involving inflammation
|
EP2398479A2
(en)
|
2009-02-19 |
2011-12-28 |
Galapagos N.V. |
Methods for identifying and compounds useful for the diagnosis and treatment of diseases involving inflammation
|
US20110319317A1
(en)
|
2009-03-04 |
2011-12-29 |
Opko Curna, Llc |
Treatment of sirtuin 1 (sirt1) related diseases by inhibition of natural antisense transcript to sirt1
|
US9464287B2
(en)
|
2009-03-16 |
2016-10-11 |
Curna, Inc. |
Treatment of nuclear factor (erythroid-derived 2)-like 2 (NRF2) related diseases by inhibition of natural antisense transcript to NRF2
|
US9708604B2
(en)
|
2009-03-17 |
2017-07-18 |
Curna, Inc. |
Treatment of delta-like 1 homolog (DLK1) related diseases by inhibition of natural antisense transcript to DLK1
|
EP2414830A2
(en)
|
2009-03-31 |
2012-02-08 |
Robert Zimmermann |
Modulation of adipose triglyceride lipase for prevention and treatment of cachexia, loss of weight and muscle atrophy and methods of screening therefor
|
WO2010112569A1
(en)
|
2009-03-31 |
2010-10-07 |
Robert Zimmermann |
Modulation of adipose triglyceride lipase for prevention and treatment of cachexia, loss of weight and muscle atrophy and methods of screening therefor
|
WO2010115841A1
(en)
|
2009-04-01 |
2010-10-14 |
Galapagos Nv |
Methods and means for treatment of osteoarthritis
|
US9145555B2
(en)
|
2009-04-02 |
2015-09-29 |
California Institute Of Technology |
Integrated—ligand-responsive microRNAs
|
JP5822822B2
(ja)
|
2009-04-17 |
2015-11-24 |
ニューヨーク ユニバーシティ |
Tnfファミリー受容体を標的とし、tnf作用を拮抗するペプチド、その組成物、方法および使用
|
EP3248618A1
(en)
|
2009-04-22 |
2017-11-29 |
Massachusetts Institute Of Technology |
Innate immune suppression enables repeated delivery of long rna molecules
|
US8318690B2
(en)
|
2009-05-01 |
2012-11-27 |
Curna, Inc. |
Treatment of hemoglobin (HBF/HBG) related diseases by inhibition of natural antisense transcript to HBF/HBG
|
CA2761152A1
(en)
|
2009-05-06 |
2010-11-11 |
Opko Curna, Llc |
Treatment of lipid transport and metabolism gene related diseases by inhibition of natural antisense transcript to a lipid transport and metabolism gene
|
CN102803492B
(zh)
|
2009-05-06 |
2016-06-29 |
库尔纳公司 |
通过抑制针对三重四脯氨酸(ttp)的天然反义转录物来治疗ttp相关疾病
|
US8957037B2
(en)
|
2009-05-18 |
2015-02-17 |
Curna, Inc. |
Treatment of reprogramming factor related diseases by inhibition of natural antisense transcript to a reprogramming factor
|
JP2012527248A
(ja)
|
2009-05-22 |
2012-11-08 |
クルナ・インコーポレーテッド |
転写因子e3(tfe3)に対する天然アンチセンス転写物の阻害によるtfe3およびインスリン受容体基質2(irs2)関連疾患の処置
|
KR101704988B1
(ko)
|
2009-05-28 |
2017-02-08 |
큐알엔에이, 인크. |
항바이러스 유전자에 대한 천연 안티센스 전사체의 억제에 의한 항바이러스 유전자 관련된 질환의 치료
|
EP2443237B1
(en)
|
2009-06-16 |
2017-02-22 |
CuRNA, Inc. |
Treatment of collagen gene related diseases by inhibition of natural antisense transcript to a collagen gene
|
KR101702689B1
(ko)
|
2009-06-16 |
2017-02-06 |
큐알엔에이, 인크. |
Pon1에 대한 천연 안티센스 전사체의 억제에 의한 파라옥소나제 1(pon1) 관련된 질환의 치료
|
CN102597238B
(zh)
|
2009-06-24 |
2016-06-29 |
库尔纳公司 |
通过抑制针对肿瘤坏死因子受体2(tnfr2)的天然反义转录物来治疗tnfr2相关的疾病
|
CN102482672B
(zh)
|
2009-06-26 |
2016-11-09 |
库尔纳公司 |
通过抑制唐氏综合征基因的天然反义转录物治疗唐氏综合征基因相关疾病
|
WO2011015573A1
(en)
|
2009-08-03 |
2011-02-10 |
Galapagos Nv |
Molecular targets and compounds, and methods to identify the same, useful in the treatment of neurodegenerative diseases
|
WO2011015572A1
(en)
|
2009-08-03 |
2011-02-10 |
Galapagos Nv |
Molecular targets and compounds, and methods to identify the same, useful in the treatment of neurodegenerative diseases
|
EP2462229B1
(en)
|
2009-08-05 |
2016-05-11 |
CuRNA, Inc. |
Treatment of insulin gene (ins) related diseases by inhibition of natural antisense transcript to an insulin gene (ins)
|
US9023822B2
(en)
|
2009-08-25 |
2015-05-05 |
Curna, Inc. |
Treatment of 'IQ motif containing GTPase activating protein' (IQGAP) related diseases by inhibition of natural antisense transcript to IQGAP
|
DK2473522T3
(en)
|
2009-09-02 |
2016-11-28 |
Genentech Inc |
Smoothened MUTANT AND METHODS OF USING THE SAME
|
EP2488210A4
(en)
|
2009-10-12 |
2014-04-30 |
Smith Holdings Llc |
METHODS AND COMPOSITIONS FOR MODULATING GENE EXPRESSION USING IN VITO OR IN VITRO-ADMINISTERED OLIGONUCLEOTIDE MEDICAMENTS
|
WO2011050194A1
(en)
|
2009-10-22 |
2011-04-28 |
Genentech, Inc. |
Methods and compositions for modulating hepsin activation of macrophage-stimulating protein
|
US20120244169A1
(en)
|
2009-11-06 |
2012-09-27 |
Fibrogen, Inc. |
Treatment for Radiation-Induced Disorders
|
CA2781887C
(en)
|
2009-11-30 |
2018-03-27 |
Genentech, Inc. |
Compositions and methods for the diagnosis and treatment of tumor
|
WO2011070177A2
(en)
|
2009-12-11 |
2011-06-16 |
Baltic Technology Development, Ltd. |
Methods of facilitating neural cell survival using gdnf family ligand (gfl) mimetics or ret signaling pathway activators
|
KR101823702B1
(ko)
|
2009-12-16 |
2018-01-30 |
큐알엔에이, 인크. |
막 결합 전사 인자 펩티다제, 부위 1(mbtps1)에 대한 천연 안티센스 전사체의 억제에 의한 mbtps1 관련 질환의 치료
|
KR101793753B1
(ko)
|
2009-12-23 |
2017-11-03 |
큐알엔에이, 인크. |
커플링방지 단백질 2(ucp2)에 대한 천연 안티센스 전사체의 저해에 의한 ucp2 관련 질환의 치료
|
DK2516648T3
(en)
|
2009-12-23 |
2018-02-12 |
Curna Inc |
TREATMENT OF HEPATOCYTE GROWTH FACTOR (HGF) RELATED DISEASES BY INHIBITION OF NATURAL ANTISENSE TRANSCRIPT AGAINST HGF
|
CN102770540B
(zh)
|
2009-12-29 |
2017-06-23 |
库尔纳公司 |
通过抑制肿瘤蛋白63(p63)的天然反义转录物而治疗p63相关疾病
|
KR101838305B1
(ko)
|
2009-12-29 |
2018-03-13 |
큐알엔에이, 인크. |
NRF1(Nuclear Respiratory Factor 1)에 대한 천연 안티센스 전사체의 억제에 의한 핵 호흡 인자 1 관련된 질환의 치료
|
RU2611187C2
(ru)
|
2010-01-04 |
2017-02-21 |
Курна, Инк. |
Лечение заболеваний, связанных с интерферон-регуляторным фактором 8 (irf8), путем ингибирования природного антисмыслового транскрипта к irf8
|
CA2786056C
(en)
|
2010-01-06 |
2023-03-14 |
Curna, Inc. |
Treatment of pancreatic developmental gene related diseases by inhibition of natural antisense transcript to a pancreatic developmental gene
|
DK2524039T3
(en)
|
2010-01-11 |
2018-03-12 |
Curna Inc |
TREATMENT OF GENDER HORMON-BINDING GLOBULIN (SHBG) RELATED DISEASES BY INHIBITION OF NATURAL ANTISENCE TRANSCRIPTS TO SHBG
|
EP2525808A2
(en)
|
2010-01-19 |
2012-11-28 |
The Trustees Of Columbia University In The City Of New York |
Osteocalcin as a treatment for male reproductive disorders
|
US8946182B2
(en)
|
2010-01-25 |
2015-02-03 |
Curna, Inc. |
Treatment of RNASE H1 related diseases by inhibition of natural antisense transcript to RNASE H1
|
CN102844435B
(zh)
|
2010-02-22 |
2017-05-10 |
库尔纳公司 |
通过抑制吡咯啉‑5‑羧酸还原酶1(pycr1)的天然反义转录物而治疗pycr1相关疾病
|
CA2787657A1
(en)
|
2010-02-23 |
2011-09-01 |
Genentech, Inc. |
Compositions and methods for the diagnosis and treatment of tumor
|
KR102049161B1
(ko)
|
2010-03-23 |
2019-11-26 |
인트렉손 코포레이션 |
치료적 단백질을 조건부로 발현하는 벡터,상기 벡터를 포함하는 숙주 세포 및 이의 용도
|
US9080171B2
(en)
|
2010-03-24 |
2015-07-14 |
RXi Parmaceuticals Corporation |
Reduced size self-delivering RNAi compounds
|
CN102858979B
(zh)
|
2010-04-09 |
2018-01-26 |
库尔纳公司 |
通过抑制成纤维细胞生长因子21(fgf21)的天然反义转录物而治疗fgf21相关疾病
|
CA2994063A1
(en)
|
2010-04-29 |
2011-11-10 |
Ionis Pharmaceuticals, Inc. |
Modulation of transthyretin expression
|
BR112012028010A2
(pt)
|
2010-05-03 |
2017-09-26 |
Genentech Inc |
anticorpo isolado, célula, ácido nucleíco isolado, método de identificação de um primeiro anticorpo que se liga a um epítopo antigênico tat425 ligado or um anticorpo, métodos de inibir o crescimento de uma célula, de tratamento terapêutico de determinação da presença de uma proteína de tat425 e de diagnóstico da presença de um tumor em um mamífero
|
KR101936011B1
(ko)
|
2010-05-03 |
2019-01-07 |
큐알엔에이, 인크. |
시르투인 (sirt)에 대한 자연 안티센스 전사체의 저해에 의한 시르투인 (sirt) 관련된 질환의 치료
|
CN109593814A
(zh)
|
2010-05-12 |
2019-04-09 |
哥伦比亚大学纽约管理委员会 |
筛选分析、鉴别药剂的方法及药物组合物
|
TWI531370B
(zh)
|
2010-05-14 |
2016-05-01 |
可娜公司 |
藉由抑制par4天然反股轉錄本治療par4相關疾病
|
EP3299464B1
(en)
|
2010-05-26 |
2019-10-02 |
CuRNA, Inc. |
Treatment of atonal homolog 1 (atoh1) related diseases by inhibition of natural antisense transcript to atoh1
|
CA2805318A1
(en)
|
2010-07-14 |
2012-01-19 |
Curna, Inc. |
Treatment of discs large homolog (dlg) related diseases by inhibition of natural antisense transcript to dlg
|
CA2808975C
(en)
|
2010-08-23 |
2018-10-30 |
Wyeth Llc |
Stable formulations of neisseria meningitidis rlp2086 antigens
|
JP5976652B2
(ja)
|
2010-09-10 |
2016-08-24 |
ワイス・エルエルシー |
髄膜炎菌orf2086抗原の非脂質化変異体
|
EP2625197B1
(en)
|
2010-10-05 |
2016-06-29 |
Genentech, Inc. |
Mutant smoothened and methods of using the same
|
US8993533B2
(en)
|
2010-10-06 |
2015-03-31 |
Curna, Inc. |
Treatment of sialidase 4 (NEU4) related diseases by inhibition of natural antisense transcript to NEU4
|
JP6049623B2
(ja)
|
2010-10-22 |
2016-12-21 |
カッパーアールエヌエー,インコーポレイテッド |
α‐L‐イズロニダーゼ(IDUA)への天然アンチセンス転写物の阻害によるIDUA関連疾患の治療
|
US20130210893A1
(en)
|
2010-10-27 |
2013-08-15 |
Curna, Inc. |
Treatment of interferon-related developmental regulator 1 (ifrd1) related diseases by inhibition of natural antisense transcript to ifrd1
|
WO2012061811A2
(en)
|
2010-11-05 |
2012-05-10 |
Fibrogen, Inc. |
Treatment method for lung remodeling diseases
|
JP6071893B2
(ja)
|
2010-11-23 |
2017-02-01 |
カッパーアールエヌエー,インコーポレイテッド |
Nanogへの天然アンチセンス転写物の阻害によるnanog関連疾患の治療
|
PT2670411T
(pt)
|
2011-02-02 |
2019-06-18 |
Excaliard Pharmaceuticals Inc |
Compostos anti sentido visando um fator de crescimento do tecido conetivo (ctfg) para utilização num método de tratamento de queloides ou cicatrizes hipertróficas
|
WO2012109495A1
(en)
|
2011-02-09 |
2012-08-16 |
Metabolic Solutions Development Company, Llc |
Cellular targets of thiazolidinediones
|
JP6189754B2
(ja)
|
2011-03-04 |
2017-08-30 |
イントレキソン コーポレーション |
タンパク質を条件的に発現するベクター
|
WO2012142458A1
(en)
|
2011-04-13 |
2012-10-18 |
Isis Pharmaceuticals, Inc. |
Antisense modulation of ptp1b expression
|
US9593330B2
(en)
|
2011-06-09 |
2017-03-14 |
Curna, Inc. |
Treatment of frataxin (FXN) related diseases by inhibition of natural antisense transcript to FXN
|
WO2012174476A2
(en)
|
2011-06-16 |
2012-12-20 |
Isis Pharmaceuticals, Inc. |
Antisense modulation of fibroblast growth factor receptor 4 expression
|
FR2979919B1
(fr)
|
2011-09-12 |
2015-12-11 |
Centre Nat Rech Scient |
Genomes lentiviraux chimeriques non-integratifs comme vaccins innovants contre vih-1
|
US8865674B2
(en)
|
2011-09-20 |
2014-10-21 |
Isis Pharmaceuticals, Inc. |
Antisense modulation of GCGR expression
|
PT2760463T
(pt)
|
2011-09-20 |
2019-02-27 |
Univ North Carolina Chapel Hill |
Regulação de canais de sódio por proteínas plunc
|
FR2980801B1
(fr)
|
2011-09-29 |
2016-02-05 |
Centre Nat Rech Scient |
Utilisation de "polyketide synthases" de type iii (pks iii) recombinantes d'algues brunes marines
|
US20130085139A1
(en)
|
2011-10-04 |
2013-04-04 |
Royal Holloway And Bedford New College |
Oligomers
|
RU2014119787A
(ru)
|
2011-10-25 |
2015-12-10 |
Айсис Фармасьютикалс, Инк. |
Антисмысловая регуляция экспрессии gccr
|
CN104334187B
(zh)
|
2012-03-09 |
2017-04-05 |
辉瑞公司 |
脑膜炎双球菌组合物及其方法
|
SA115360586B1
(ar)
|
2012-03-09 |
2017-04-12 |
فايزر انك |
تركيبات لعلاج الالتهاب السحائي البكتيري وطرق لتحضيرها
|
KR20140136488A
(ko)
|
2012-03-15 |
2014-11-28 |
큐알엔에이, 인크. |
뇌 유래 신경영양 인자(bdnf)에 대한 천연 안티센스 전사체의 저해에 의한 뇌 유래 신경영양 인자(bdnf)관련 질환의 치료
|
WO2014041179A1
(en)
|
2012-09-17 |
2014-03-20 |
Chemedest Ltd. |
Treatment of peripheral neuropathy using gfr(alpha)3 type receptor agonists
|
RU2656162C2
(ru)
|
2012-10-22 |
2018-05-31 |
Фоунтейн Биофарма Инк. |
Антитела к интерлейкину 6 и их применение
|
WO2014076196A1
(en)
|
2012-11-15 |
2014-05-22 |
Santaris Pharma A/S |
Anti apob antisense conjugate compounds
|
JP6446377B2
(ja)
|
2013-03-08 |
2018-12-26 |
ファイザー・インク |
免疫原性融合ポリペプチド
|
EP2972322B1
(en)
|
2013-03-14 |
2019-03-06 |
Galapagos NV |
Molecular targets and compounds, and methods to identify the same, useful in the treatment of fibrotic diseases
|
WO2014139885A2
(en)
|
2013-03-14 |
2014-09-18 |
Galapagos Nv |
Molecular targets and compounds, and methods to identify the same, useful in the treatment of diseases associated with epithelial mesenchymal transition
|
US9952202B2
(en)
|
2013-03-14 |
2018-04-24 |
Galapagos Nv |
Methods of identifying compounds for the treatment of fibrosis by using S1PR5
|
US10052364B2
(en)
|
2013-03-15 |
2018-08-21 |
The Trustees Of Columbia University In The City Of New York |
Osteocalcin as a treatment for cognitive disorders
|
ES2862125T3
(es)
|
2013-06-13 |
2021-10-07 |
Antisense Therapeutics Ltd |
Terapia combinada para acromegalia
|
EP3041935A1
(en)
|
2013-09-05 |
2016-07-13 |
Sage Therapeutics, Inc. |
Antisense-induced exon2 inclusion in acid alpha-glucosidase
|
WO2015033251A2
(en)
|
2013-09-08 |
2015-03-12 |
Pfizer Inc. |
Neisseria meningitidis compositions and methods thereof
|
US10036020B2
(en)
|
2013-09-19 |
2018-07-31 |
The United States Of America, As Represented By The Secretary, Department Of Health & Human Services |
Compositions and methods for inhibiting JC virus (JCV)
|
WO2015116902A1
(en)
|
2014-01-31 |
2015-08-06 |
Genentech, Inc. |
G-protein coupled receptors in hedgehog signaling
|
US20170044232A1
(en)
|
2014-02-04 |
2017-02-16 |
Genentech, Inc. |
Mutant smoothened and methods of using the same
|
KR101605421B1
(ko)
|
2014-03-05 |
2016-03-23 |
국립암센터 |
B 세포 림프종 세포를 특이적으로 인지하는 단일클론항체 및 이의 용도
|
WO2015171918A2
(en)
|
2014-05-07 |
2015-11-12 |
Louisiana State University And Agricultural And Mechanical College |
Compositions and uses for treatment thereof
|
GB2526867A
(en)
|
2014-06-05 |
2015-12-09 |
Oxitec Ltd |
Gene expression system
|
CA2985344A1
(en)
|
2014-06-26 |
2015-12-30 |
The Trustees Of Columbia University In The City Of New York |
Inhibition of serotonin expression in gut enteroendocrine cells results in conversion to insulin-positive cells
|
EP3169310A1
(en)
|
2014-07-15 |
2017-05-24 |
Life Technologies Corporation |
Compositions with lipid aggregates and methods for efficient delivery of molecules to cells
|
WO2016033424A1
(en)
|
2014-08-29 |
2016-03-03 |
Genzyme Corporation |
Methods for the prevention and treatment of major adverse cardiovascular events using compounds that modulate apolipoprotein b
|
US11191811B2
(en)
|
2014-11-19 |
2021-12-07 |
The Trustees Of Columbia University In The City Of New York |
Osteocalcin as a treatment for frailty associated with aging
|
US10308705B2
(en)
|
2015-02-06 |
2019-06-04 |
The University Of North Carolina At Chapel Hill |
Optimized human clotting factor VIII gene expression cassettes and their use
|
CN107249626A
(zh)
|
2015-02-19 |
2017-10-13 |
辉瑞大药厂 |
脑膜炎奈瑟球菌组合物及其方法
|
MA41795A
(fr)
|
2015-03-18 |
2018-01-23 |
Sarepta Therapeutics Inc |
Exclusion d'un exon induite par des composés antisens dans la myostatine
|
US10849917B2
(en)
|
2015-06-01 |
2020-12-01 |
Sarepta Therapeutics, Inc. |
Antisense-induced exon exclusion in type VII collagen
|
WO2017058881A1
(en)
|
2015-09-28 |
2017-04-06 |
The Trustees Of Columbia University In The City Of New York |
Use of pentoxifylline with immune checkpoint-blockade therapies for the treatment of melanoma
|
EP3359668A4
(en)
|
2015-10-09 |
2019-06-05 |
Sarepta Therapeutics, Inc. |
COMPOSITIONS AND METHODS OF TREATING DUCHENNE MUSCLE DYSTROPHY AND ASSOCIATED ILLNESSES THEREOF
|
EP3347373A1
(en)
|
2015-10-10 |
2018-07-18 |
Intrexon Corporation |
Improved therapeutic control of proteolytically sensitive, destabilized forms of interleukin-12
|
EP3370734B1
(en)
|
2015-11-05 |
2023-01-04 |
Children's Hospital Los Angeles |
Antisense oligo for use in treating acute myeloid leukemia
|
CN106699889A
(zh)
|
2015-11-18 |
2017-05-24 |
礼进生物医药科技(上海)有限公司 |
抗pd-1抗体及其治疗用途
|
CN117683769A
(zh)
|
2015-12-23 |
2024-03-12 |
瑞普鲁卡私人有限公司 |
核酸寡聚体及其用途
|
AU2017213826A1
(en)
|
2016-02-04 |
2018-08-23 |
Curis, Inc. |
Mutant smoothened and methods of using the same
|
AU2017222450A1
(en)
|
2016-02-22 |
2018-09-27 |
The University Of North Carolina At Chapel Hill |
Peptide inhibitors of calcium channels
|
KR102522059B1
(ko)
|
2016-04-18 |
2023-04-14 |
사렙타 쎄러퓨틱스 인코퍼레이티드 |
안티센스 올리고머, 및 산성 알파-글루코시다제 유전자와 연관된 질환을 치료하기 위한 이의 사용 방법
|
BR112019002771A2
(pt)
|
2016-08-12 |
2019-05-14 |
Oxitec Ltd |
polinucleotídeo de módulo de controle de união de doublesex, sistema de expressão de gene, plasmídeo vetor de expressão, inseto geneticamente engenheirado, métodos para produzir insetos geneticamente engenheirados, para cultivar seletivamente insetos macho geneticamente engenheirados, para reduzir uma população de inseto selvagem, para criar um mosquito aedes aegypti transgênico e para detectar a presença de uma molécula de dna, local alvo cromossômico de aedes aegypti, mosquito aedes aegypti geneticamente engenheirado, molécula de dna, e, kit de detecção de dna.
|
BR112019009446A2
(pt)
|
2016-11-09 |
2019-07-30 |
Intrexon Corp |
construtos de expressão da frataxina
|
KR102567845B1
(ko)
|
2017-01-31 |
2023-08-17 |
화이자 인코포레이티드 |
네이세리아 메닌기티디스 조성물 및 그의 방법
|
WO2018209288A1
(en)
|
2017-05-12 |
2018-11-15 |
Massachusetts Institute Of Technology |
Argonaute protein-double stranded rna complexes and uses related thereto
|
US11999953B2
(en)
|
2017-09-13 |
2024-06-04 |
The Children's Medical Center Corporation |
Compositions and methods for treating transposon associated diseases
|
JP7394753B2
(ja)
|
2017-10-18 |
2023-12-08 |
サレプタ セラピューティクス, インコーポレイテッド |
アンチセンスオリゴマー化合物
|
KR101915949B1
(ko)
|
2018-01-09 |
2018-11-07 |
주식회사 쎌바이오텍 |
유전자 발현 카세트 및 그를 포함하는 발현벡터
|
AR117409A1
(es)
|
2018-03-29 |
2021-08-04 |
Oxitec Ltd |
Noctuidas autolimitantes
|
EP3772928A4
(en)
|
2018-04-06 |
2021-12-29 |
Children's Medical Center Corporation |
Compositions and methods for somatic cell reprogramming and modulating imprinting
|
CA3109209A1
(en)
|
2018-08-10 |
2020-02-13 |
Eutilex Co., Ltd. |
Chimeric antigen receptor that binds hla-dr and car-t cell
|
MA52650A1
(fr)
|
2018-08-14 |
2021-12-31 |
Oxitec Ltd |
Arthropodes mâles stériles à sélection automatique
|
BR112021012037A2
(pt)
|
2018-12-21 |
2021-11-03 |
Ose Immunotherapeutics |
Molécula anti-pd-1/il-7 bifuncional
|
US20220025050A1
(en)
|
2018-12-21 |
2022-01-27 |
Ose Immunotherapeutics |
Bifunctional molecule directed against human pd-1
|
EA202191763A1
(ru)
|
2018-12-21 |
2022-03-10 |
Озе Иммьюнотерапьютикс |
Бифункциональная молекула анти-pd-1/sirp
|
SG11202106347PA
(en)
|
2018-12-21 |
2021-07-29 |
Ose Immunotherapeutics |
Humanized anti-human-pd-1 antibody
|
WO2020165374A1
(en)
|
2019-02-14 |
2020-08-20 |
Ose Immunotherapeutics |
Bifunctional molecule comprising il-15ra
|
AU2020236937B2
(en)
|
2019-03-08 |
2023-06-15 |
Obsidian Therapeutics, Inc. |
CD40L compositions and methods for tunable regulation
|
EP3835421A1
(en)
|
2019-12-11 |
2021-06-16 |
Consejo Superior de Investigaciones Científicas (CSIC) |
Vectors for tissue specific transcriptomics
|
MX2022008415A
(es)
|
2020-01-08 |
2022-08-08 |
Obsidian Therapeutics Inc |
Composiciones y metodos para la regulacion ajustable de la transcripcion.
|
WO2021174742A1
(zh)
|
2020-03-06 |
2021-09-10 |
生物岛实验室 |
一种动物的制备方法
|
EP4240408A1
(en)
|
2020-11-05 |
2023-09-13 |
Neoimmunetech, Inc. |
Method of treating a tumor with a combination of an il-7 protein and a nucleotide vaccine
|
EP4019539A1
(en)
|
2020-12-22 |
2022-06-29 |
Consejo Superior de Investigaciones Científicas (CSIC) |
Recombinant bacterium and uses thereof
|
WO2022226291A1
(en)
|
2021-04-22 |
2022-10-27 |
Dana-Farber Cancer Institute, Inc. |
Compositions and methods for treating cancer
|