PT2760463T - Regulação de canais de sódio por proteínas plunc - Google Patents

Regulação de canais de sódio por proteínas plunc

Info

Publication number
PT2760463T
PT2760463T PT12833524T PT12833524T PT2760463T PT 2760463 T PT2760463 T PT 2760463T PT 12833524 T PT12833524 T PT 12833524T PT 12833524 T PT12833524 T PT 12833524T PT 2760463 T PT2760463 T PT 2760463T
Authority
PT
Portugal
Prior art keywords
regulation
sodium channels
plunc proteins
plunc
proteins
Prior art date
Application number
PT12833524T
Other languages
English (en)
Inventor
Tarran Robert
Jack Stutts Monroe
Donaldson Scott
Original Assignee
Univ North Carolina Chapel Hill
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ North Carolina Chapel Hill filed Critical Univ North Carolina Chapel Hill
Publication of PT2760463T publication Critical patent/PT2760463T/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pulmonology (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
PT12833524T 2011-09-20 2012-09-19 Regulação de canais de sódio por proteínas plunc PT2760463T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201161536647P 2011-09-20 2011-09-20

Publications (1)

Publication Number Publication Date
PT2760463T true PT2760463T (pt) 2019-02-27

Family

ID=47914825

Family Applications (1)

Application Number Title Priority Date Filing Date
PT12833524T PT2760463T (pt) 2011-09-20 2012-09-19 Regulação de canais de sódio por proteínas plunc

Country Status (13)

Country Link
US (2) US9127040B2 (pt)
EP (1) EP2760463B1 (pt)
AU (2) AU2012312520A1 (pt)
BR (1) BR112014006535A2 (pt)
CA (1) CA2849267A1 (pt)
DK (1) DK2760463T3 (pt)
ES (1) ES2716723T3 (pt)
HK (1) HK1200729A1 (pt)
HU (1) HUE041740T2 (pt)
IL (1) IL231614B (pt)
PL (1) PL2760463T3 (pt)
PT (1) PT2760463T (pt)
WO (1) WO2013043720A1 (pt)

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US10988454B2 (en) 2017-09-14 2021-04-27 Abbvie Overseas S.À.R.L. Modulators of the cystic fibrosis transmembrane conductance regulator protein and methods of use
WO2019193062A1 (en) 2018-04-03 2019-10-10 Abbvie S.Á.R.L Substituted pyrrolidines and their use
EP3747882A1 (en) 2019-06-03 2020-12-09 AbbVie Overseas S.à r.l. Prodrug modulators of the cystic fibrosis transmembrane conductance regulator protein and methods of use
WO2021011327A1 (en) 2019-07-12 2021-01-21 Orphomed, Inc. Compound for treating cystic fibrosis
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US20220213041A1 (en) 2021-01-06 2022-07-07 AbbVie Global Enterprises Ltd. Modulators of the Cystic Fibrosis Transmembrane Conductance Regulator Protein and Methods of Use
EP4314010A1 (en) * 2021-03-22 2024-02-07 The University of North Carolina at Chapel Hill Modified peptidomimetics and methods of use
KR20240076791A (ko) 2021-09-03 2024-05-30 젠자임 코포레이션 인돌 화합물 및 사용 방법
EP4396176A1 (en) 2021-09-03 2024-07-10 Genzyme Corporation Indole compounds and uses thereof in the treatement of cystic fibrosis
WO2024054845A1 (en) 2022-09-07 2024-03-14 Sionna Therapeutics Macrocycic compounds, compositions, and methods of using thereof
WO2024054851A1 (en) 2022-09-07 2024-03-14 Sionna Therapeutics Macrocyclic compounds, compositions and methods of using thereof
WO2024054840A1 (en) 2022-09-07 2024-03-14 Sionna Therapeutics Macrocyclic compounds, compositions, and methods of using thereof

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Also Published As

Publication number Publication date
ES2716723T3 (es) 2019-06-14
US9127040B2 (en) 2015-09-08
PL2760463T3 (pl) 2019-05-31
WO2013043720A1 (en) 2013-03-28
US20160159879A1 (en) 2016-06-09
AU2012312520A1 (en) 2014-05-08
HK1200729A1 (en) 2015-08-14
DK2760463T3 (en) 2019-03-18
IL231614B (en) 2019-02-28
AU2018200871A1 (en) 2018-02-22
BR112014006535A2 (pt) 2017-03-28
EP2760463A1 (en) 2014-08-06
HUE041740T2 (hu) 2019-05-28
IL231614A0 (en) 2014-05-28
US20140228276A1 (en) 2014-08-14
CA2849267A1 (en) 2013-03-28
EP2760463A4 (en) 2015-07-29
EP2760463B1 (en) 2018-11-21

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