HRP20120046T1 - Nerameksan za uporabu kod liječenja subakutnog tinitusa - Google Patents
Nerameksan za uporabu kod liječenja subakutnog tinitusa Download PDFInfo
- Publication number
- HRP20120046T1 HRP20120046T1 HR20120046T HRP20120046T HRP20120046T1 HR P20120046 T1 HRP20120046 T1 HR P20120046T1 HR 20120046 T HR20120046 T HR 20120046T HR P20120046 T HRP20120046 T HR P20120046T HR P20120046 T1 HRP20120046 T1 HR P20120046T1
- Authority
- HR
- Croatia
- Prior art keywords
- neramexane
- pharmaceutically acceptable
- acceptable salt
- use according
- tinnitus
- Prior art date
Links
- OGZQTTHDGQBLBT-UHFFFAOYSA-N neramexane Chemical compound CC1(C)CC(C)(C)CC(C)(N)C1 OGZQTTHDGQBLBT-UHFFFAOYSA-N 0.000 title claims abstract 22
- 229950004543 neramexane Drugs 0.000 title claims abstract 22
- 208000009205 Tinnitus Diseases 0.000 title claims abstract 14
- 231100000886 tinnitus Toxicity 0.000 title claims abstract 14
- 150000003839 salts Chemical class 0.000 claims abstract 21
- 230000002265 prevention Effects 0.000 claims abstract 4
- CLUKHUGGXSIGRX-UHFFFAOYSA-N methanesulfonic acid;1,3,3,5,5-pentamethylcyclohexan-1-amine Chemical group CS(O)(=O)=O.CC1(C)CC(C)(C)CC(C)(N)C1 CLUKHUGGXSIGRX-UHFFFAOYSA-N 0.000 claims 6
- 239000008177 pharmaceutical agent Substances 0.000 claims 4
- 239000000935 antidepressant agent Substances 0.000 claims 3
- 229940005513 antidepressants Drugs 0.000 claims 3
- 229940124834 selective serotonin reuptake inhibitor Drugs 0.000 claims 3
- 239000012896 selective serotonin reuptake inhibitor Substances 0.000 claims 3
- SFLSHLFXELFNJZ-QMMMGPOBSA-N (-)-norepinephrine Chemical compound NC[C@H](O)C1=CC=C(O)C(O)=C1 SFLSHLFXELFNJZ-QMMMGPOBSA-N 0.000 claims 2
- 206010011878 Deafness Diseases 0.000 claims 2
- 230000001430 anti-depressive effect Effects 0.000 claims 2
- 229940125713 antianxiety drug Drugs 0.000 claims 2
- 239000003937 drug carrier Substances 0.000 claims 2
- 238000009472 formulation Methods 0.000 claims 2
- 230000010370 hearing loss Effects 0.000 claims 2
- 231100000888 hearing loss Toxicity 0.000 claims 2
- 208000016354 hearing loss disease Diseases 0.000 claims 2
- 239000000203 mixture Substances 0.000 claims 2
- 229960002748 norepinephrine Drugs 0.000 claims 2
- SFLSHLFXELFNJZ-UHFFFAOYSA-N norepinephrine Natural products NCC(O)C1=CC=C(O)C(O)=C1 SFLSHLFXELFNJZ-UHFFFAOYSA-N 0.000 claims 2
- 239000000546 pharmaceutical excipient Substances 0.000 claims 2
- 229940094659 Dopamine reuptake inhibitor Drugs 0.000 claims 1
- 241001229135 Nassa Species 0.000 claims 1
- 239000005557 antagonist Substances 0.000 claims 1
- 239000002249 anxiolytic agent Substances 0.000 claims 1
- 239000003210 dopamine receptor blocking agent Substances 0.000 claims 1
- 239000000221 dopamine uptake inhibitor Substances 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 239000012729 immediate-release (IR) formulation Substances 0.000 claims 1
- 239000003112 inhibitor Substances 0.000 claims 1
- 239000003446 ligand Substances 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 239000002767 noradrenalin uptake inhibitor Substances 0.000 claims 1
- 230000002474 noradrenergic effect Effects 0.000 claims 1
- 229940127221 norepinephrine reuptake inhibitor Drugs 0.000 claims 1
- 239000003723 serotonin 1A agonist Substances 0.000 claims 1
- 230000002295 serotoninergic effect Effects 0.000 claims 1
- 238000013268 sustained release Methods 0.000 claims 1
- 239000012730 sustained-release form Substances 0.000 claims 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Otolaryngology (AREA)
- Neurosurgery (AREA)
- Hospice & Palliative Care (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Percussion Or Vibration Massage (AREA)
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US99339607P | 2007-09-12 | 2007-09-12 | |
| EP07253630 | 2007-09-12 | ||
| US6708308P | 2008-02-25 | 2008-02-25 | |
| US6693108P | 2008-02-25 | 2008-02-25 | |
| US6702608P | 2008-02-25 | 2008-02-25 | |
| EP08004776 | 2008-03-14 | ||
| EP08004778 | 2008-03-14 | ||
| EP08004777 | 2008-03-14 | ||
| PCT/EP2008/007421 WO2009033652A1 (en) | 2007-09-12 | 2008-09-10 | 1-amino-alkylcyclohexane derivatives for the treatment of cochlear tinnitus |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20120046T1 true HRP20120046T1 (hr) | 2012-02-29 |
Family
ID=40451596
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HR20120046T HRP20120046T1 (hr) | 2007-09-12 | 2012-01-16 | Nerameksan za uporabu kod liječenja subakutnog tinitusa |
Country Status (21)
| Country | Link |
|---|---|
| US (6) | US20110086916A1 (ko) |
| EP (6) | EP2200598A1 (ko) |
| JP (6) | JP5613053B2 (ko) |
| KR (4) | KR20100052556A (ko) |
| CN (4) | CN101801366A (ko) |
| AR (3) | AR071728A1 (ko) |
| AT (1) | ATE532507T1 (ko) |
| AU (4) | AU2008298017B2 (ko) |
| BR (2) | BRPI0816690A2 (ko) |
| CA (4) | CA2699209A1 (ko) |
| DK (1) | DK2200600T3 (ko) |
| ES (5) | ES2510565T3 (ko) |
| HR (1) | HRP20120046T1 (ko) |
| MX (4) | MX2010002733A (ko) |
| PL (1) | PL2200600T3 (ko) |
| PT (1) | PT2200600E (ko) |
| RU (1) | RU2011137131A (ko) |
| SI (1) | SI2200600T1 (ko) |
| TW (3) | TW200918042A (ko) |
| WO (4) | WO2009033650A1 (ko) |
| ZA (4) | ZA201001262B (ko) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL2200600T3 (pl) * | 2007-09-12 | 2012-04-30 | Merz Pharma Gmbh & Co Kgaa | Nerameksan do zastosowania w leczeniu podostrego szumu usznego |
| US20110294890A1 (en) * | 2010-05-28 | 2011-12-01 | Merz Pharma Gmbh & Co. Kgaa | Neramexane for the treatment or prevention of inner ear disorders |
| WO2011160839A1 (en) | 2010-06-24 | 2011-12-29 | Merz Pharma Gmbh & Co. Kgaa | Neramexane multiple unit dosage form |
| US20130296427A1 (en) * | 2011-01-20 | 2013-11-07 | Merz Pharma Gmbh & Co. Kgaa | Neramexane for the treatment or prevention of tinnitus related with stress or acute hearing loss |
| CA2904055A1 (en) * | 2013-03-06 | 2014-09-12 | Acorda Therapeutics, Inc. | Therapeutic dosing of a neuregulin or a fragment thereof for treatment or prophylaxis of heart failure |
| CN106535883A (zh) * | 2014-04-28 | 2017-03-22 | 杏林制药株式会社 | 耳鸣患者的治疗用药剂 |
| EP3138559A4 (en) * | 2014-04-28 | 2017-10-25 | Kyorin Pharmaceutical Co., Ltd. | Drug for treatment of tinnitus patients |
| CA2999467C (en) | 2014-10-23 | 2023-10-10 | Arena Pharmaceuticals, Inc. | Method of treating conditions related to the pgi2 receptor |
| PL3297628T3 (pl) * | 2015-05-18 | 2021-12-06 | Sensorion | Azasetron do stosowania w leczeniu niedosłuchu |
| KR101893604B1 (ko) | 2015-08-27 | 2018-08-30 | 경희대학교 산학협력단 | 칸디다 유틸리스 추출물을 포함하는 난청의 예방 또는 치료용 조성물 |
| CN105924362B (zh) * | 2016-02-05 | 2018-08-17 | 上海龙翔生物医药开发有限公司 | 芳香环丙基胺类化合物、其药学上可接受的盐、其制备方法及其用途 |
| CN110582271B (zh) | 2017-03-01 | 2022-06-14 | 阿瑞那制药公司 | 包含pgi2受体激动剂的组合物及其制备方法 |
| KR102268893B1 (ko) | 2020-01-16 | 2021-06-24 | 경북대학교 산학협력단 | 림노트릭스 속 knua002 균주를 포함하는 난청의 예방 또는 치료용 조성물 |
| CN111477199B (zh) * | 2020-04-02 | 2021-11-30 | 北京瑞迪欧文化传播有限责任公司 | 一种嵌入式音乐控制系统 |
Family Cites Families (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5811128A (en) | 1986-10-24 | 1998-09-22 | Southern Research Institute | Method for oral or rectal delivery of microencapsulated vaccines and compositions therefor |
| US4849222A (en) | 1987-03-24 | 1989-07-18 | The Procter & Gamble Company | Mixtures for treating hypercholesterolemia |
| JP2670680B2 (ja) | 1988-02-24 | 1997-10-29 | 株式会社ビーエムジー | 生理活性物質含有ポリ乳酸系微小球およびその製造法 |
| US5288502A (en) | 1991-10-16 | 1994-02-22 | The University Of Texas System | Preparation and uses of multi-phase microspheres |
| CA2172509C (en) | 1993-10-22 | 2010-08-24 | Jeffrey L. Cleland | Methods and compositions for microencapsulation of antigens for use as vaccines |
| DE19528388A1 (de) * | 1995-08-02 | 1997-02-06 | Hans Peter Prof Dr Med Zenner | Verwendung von Adamantan-Derivaten zur Behandlung von Erkrankungen des Innenohrs |
| AU4424697A (en) * | 1996-09-11 | 1998-04-02 | Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The | The use of functional n-methyl-d-aspartate antagonists to ameliorate or prevent aminoglycoside-induced ototoxicity |
| EP1009732B1 (en) * | 1997-06-30 | 2003-05-21 | MERZ + CO. GmbH & Co. | 1-amino-alkylcyclohexane nmda receptor antagonists |
| US6071966A (en) * | 1997-06-30 | 2000-06-06 | Merz + Co. Gmbh & Co. | 1-amino-alkylcyclohexane NMDA receptor antagonists |
| JP2003531187A (ja) * | 2000-04-26 | 2003-10-21 | ワーナー−ランバート・カンパニー、リミテッド、ライアビリティ、カンパニー | サブタイプ選択的ｎｍｄａ受容体アンタゴニストとしてのシクロヘキシルアミン誘導体 |
| DE10048969A1 (de) * | 2000-08-23 | 2002-03-14 | Mueller Schwefe Gerhard | Verwendung von Flupirtin zur Tinnitusbehandlung |
| US20030236288A1 (en) * | 2002-02-28 | 2003-12-25 | Karl Schoenafinger | Use of substituted 3-phenyl-5-alkoxy-3H-(1,3,4)-oxadizol-2-ones for inhibiting pancreatic lipase |
| JP2004021734A (ja) | 2002-06-18 | 2004-01-22 | Nokia Corp | キーパッドおよびキーパッドシステム |
| US7086532B2 (en) * | 2003-07-16 | 2006-08-08 | Allergan, Inc. | Titration/compliance pack with increasing doses |
| EP1545551A4 (en) * | 2002-09-06 | 2008-10-22 | Durect Corp | DISTRIBUTION OF MODULATORS OF THE GLUTAMAT-MEDIATED NEUROTRANSMISSION TO THE INNER EAR |
| DE10252665A1 (de) | 2002-11-11 | 2004-06-03 | Grünenthal GmbH | 4-Aminomethyl-1-aryl-cyclohexylamin-Derivate |
| EA010430B1 (ru) * | 2003-05-27 | 2008-08-29 | Форест Лэборэтериз, Инк. | Сочетание антагониста nmda-рецептора и селективного ингибитора обратного захвата серотонина для лечения депрессии и других психических расстройств |
| AR046314A1 (es) * | 2003-11-05 | 2005-11-30 | Merz Pharma Gmbh & Co Kgaa | Composiciones que comprenden ciclohexilaminas y aminoadamantanos |
| US20060002999A1 (en) | 2004-06-17 | 2006-01-05 | Forest Laboratories, Inc. | Immediate release formulations of 1-aminocyclohexane compounds, memantine and neramexane |
| KR20090033410A (ko) | 2004-06-17 | 2009-04-02 | 메르츠 파마 게엠베하 운트 코. 카가아 | 메만타인 또는 네라멕산의 직접 압축으로 제조된 마실수 있는 즉시 방출형 제제 |
| US20060205822A1 (en) * | 2004-12-22 | 2006-09-14 | Forest Laboratories, Inc. | 1-Aminocyclohexane derivatives for the treatment of multiple sclerosis, emotional lability and pseudobulbar affect |
| US20060264897A1 (en) * | 2005-01-24 | 2006-11-23 | Neurosystec Corporation | Apparatus and method for delivering therapeutic and/or other agents to the inner ear and to other tissues |
| WO2006096518A2 (en) * | 2005-03-04 | 2006-09-14 | Neurosystec Corporation | Improved gacyclidine formulations |
| TWI265036B (en) * | 2005-04-29 | 2006-11-01 | Guo-Ming Huang | Safety injector and method of operating the same |
| US8062205B2 (en) * | 2005-05-18 | 2011-11-22 | Gt Urological, Llc | Drug elution for implantable incontinence devices |
| CN1896729A (zh) | 2005-07-15 | 2007-01-17 | 复旦大学附属中山医院 | 纳米药物自组装双稳态量子线阵列及其制备方法 |
| US20070141148A1 (en) * | 2005-11-30 | 2007-06-21 | Merz Pharma Gmbh & Co. Kgaa | Neramexane MR matrix tablet |
| TW200819458A (en) * | 2006-06-23 | 2008-05-01 | Merz Pharma Gmbh & Co Kgaa | Metabotropic glutamate receptor modulators |
| PL2200600T3 (pl) * | 2007-09-12 | 2012-04-30 | Merz Pharma Gmbh & Co Kgaa | Nerameksan do zastosowania w leczeniu podostrego szumu usznego |
| TW201010691A (en) * | 2008-06-12 | 2010-03-16 | Merz Pharma Gmbh & Co Kgaa | 1-amino-alkylcyclohexane derivatives for the treatment of sleep disorders |
| TW201006463A (en) * | 2008-06-26 | 2010-02-16 | Merz Pharma Gmbh & Co Kgaa | Pharmaceutical compositions comprising aminocyclohexane derivatives |
| AU2009291244A1 (en) * | 2008-09-10 | 2010-03-18 | Merz Pharma Gmbh & Co. Kgaa | 1-amino-alkylcyclohexane derivatives for the treatment of cognitive impairment in tinnitus |
| US20110294890A1 (en) * | 2010-05-28 | 2011-12-01 | Merz Pharma Gmbh & Co. Kgaa | Neramexane for the treatment or prevention of inner ear disorders |
| US20130296427A1 (en) * | 2011-01-20 | 2013-11-07 | Merz Pharma Gmbh & Co. Kgaa | Neramexane for the treatment or prevention of tinnitus related with stress or acute hearing loss |
-
2008
- 2008-09-10 PL PL08801987T patent/PL2200600T3/pl unknown
- 2008-09-10 CN CN200880106973A patent/CN101801366A/zh active Pending
- 2008-09-10 EP EP08801984A patent/EP2200598A1/en not_active Withdrawn
- 2008-09-10 JP JP2010524392A patent/JP5613053B2/ja not_active Expired - Fee Related
- 2008-09-10 CN CN200880106975A patent/CN101795679A/zh active Pending
- 2008-09-10 MX MX2010002733A patent/MX2010002733A/es not_active Application Discontinuation
- 2008-09-10 US US12/733,577 patent/US20110086916A1/en not_active Abandoned
- 2008-09-10 WO PCT/EP2008/007419 patent/WO2009033650A1/en active Application Filing
- 2008-09-10 EP EP11005567.0A patent/EP2386299B1/en active Active
- 2008-09-10 US US12/733,646 patent/US9498450B2/en not_active Expired - Fee Related
- 2008-09-10 CA CA2699209A patent/CA2699209A1/en not_active Abandoned
- 2008-09-10 CA CA2699213A patent/CA2699213A1/en not_active Abandoned
- 2008-09-10 CA CA2699210A patent/CA2699210A1/en not_active Abandoned
- 2008-09-10 ES ES08801986.4T patent/ES2510565T3/es active Active
- 2008-09-10 US US12/733,582 patent/US9468610B2/en not_active Expired - Fee Related
- 2008-09-10 EP EP08801986.4A patent/EP2203163B1/en active Active
- 2008-09-10 AR ARP080103938A patent/AR071728A1/es not_active Application Discontinuation
- 2008-09-10 WO PCT/EP2008/007420 patent/WO2009033651A1/en active Application Filing
- 2008-09-10 EP EP08801987A patent/EP2200600B1/en active Active
- 2008-09-10 AU AU2008298017A patent/AU2008298017B2/en not_active Ceased
- 2008-09-10 EP EP08801985.6A patent/EP2200599B1/en active Active
- 2008-09-10 KR KR1020107007786A patent/KR20100052556A/ko not_active Application Discontinuation
- 2008-09-10 PT PT08801987T patent/PT2200600E/pt unknown
- 2008-09-10 AT AT08801987T patent/ATE532507T1/de active
- 2008-09-10 ES ES11005567.0T patent/ES2596262T3/es active Active
- 2008-09-10 TW TW097134699A patent/TW200918042A/zh unknown
- 2008-09-10 CA CA2699207A patent/CA2699207A1/en not_active Abandoned
- 2008-09-10 ES ES08801985.6T patent/ES2604945T3/es active Active
- 2008-09-10 JP JP2010524394A patent/JP5563460B2/ja not_active Expired - Fee Related
- 2008-09-10 WO PCT/EP2008/007421 patent/WO2009033652A1/en active Application Filing
- 2008-09-10 BR BRPI0816690A patent/BRPI0816690A2/pt not_active IP Right Cessation
- 2008-09-10 MX MX2010002734A patent/MX2010002734A/es not_active Application Discontinuation
- 2008-09-10 CN CN200880106925A patent/CN101801365A/zh active Pending
- 2008-09-10 BR BRPI0816712A patent/BRPI0816712A2/pt not_active IP Right Cessation
- 2008-09-10 CN CN200880106404A patent/CN101835469A/zh active Pending
- 2008-09-10 MX MX2010002736A patent/MX2010002736A/es not_active Application Discontinuation
- 2008-09-10 SI SI200830530T patent/SI2200600T1/sl unknown
- 2008-09-10 ES ES12006826.7T patent/ES2562709T3/es active Active
- 2008-09-10 KR KR1020107007787A patent/KR20100052557A/ko not_active Application Discontinuation
- 2008-09-10 TW TW097134705A patent/TW200922544A/zh unknown
- 2008-09-10 WO PCT/EP2008/007418 patent/WO2009033649A1/en active Application Filing
- 2008-09-10 US US12/733,645 patent/US8877814B2/en not_active Expired - Fee Related
- 2008-09-10 MX MX2010002735A patent/MX2010002735A/es unknown
- 2008-09-10 KR KR1020107007793A patent/KR20100052558A/ko not_active Application Discontinuation
- 2008-09-10 JP JP2010524393A patent/JP5612473B2/ja not_active Expired - Fee Related
- 2008-09-10 ES ES08801987T patent/ES2377253T3/es active Active
- 2008-09-10 AU AU2008298018A patent/AU2008298018C1/en not_active Ceased
- 2008-09-10 JP JP2010524395A patent/JP5563461B2/ja not_active Expired - Fee Related
- 2008-09-10 AR ARP080103936A patent/AR070025A1/es not_active Application Discontinuation
- 2008-09-10 KR KR1020107007795A patent/KR20100052559A/ko not_active Application Discontinuation
- 2008-09-10 AU AU2008298016A patent/AU2008298016B2/en not_active Ceased
- 2008-09-10 TW TW097134701A patent/TW200927087A/zh unknown
- 2008-09-10 AU AU2008298015A patent/AU2008298015B2/en not_active Ceased
- 2008-09-10 DK DK08801987.2T patent/DK2200600T3/da active
- 2008-09-10 EP EP12006826.7A patent/EP2548552B1/en active Active
- 2008-09-10 AR ARP080103937A patent/AR070026A1/es not_active Application Discontinuation
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2010
- 2010-02-22 ZA ZA2010/01262A patent/ZA201001262B/en unknown
- 2010-02-22 ZA ZA2010/01261A patent/ZA201001261B/en unknown
- 2010-02-22 ZA ZA2010/01264A patent/ZA201001264B/en unknown
- 2010-02-22 ZA ZA2010/01263A patent/ZA201001263B/en unknown
-
2011
- 2011-09-08 RU RU2011137131/15A patent/RU2011137131A/ru not_active Application Discontinuation
-
2012
- 2012-01-16 HR HR20120046T patent/HRP20120046T1/hr unknown
-
2014
- 2014-06-12 JP JP2014121268A patent/JP5784188B2/ja not_active Expired - Fee Related
- 2014-06-12 JP JP2014121269A patent/JP5784189B2/ja not_active Expired - Fee Related
- 2014-09-30 US US14/501,438 patent/US20150018425A1/en not_active Abandoned
-
2016
- 2016-10-12 US US15/291,527 patent/US20170027885A1/en not_active Abandoned
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